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https://www.readbyqxmd.com/read/29765399/a-seasonal-time-series-model-based-on-gene-expression-programming-for-predicting-financial-distress
#1
Ching-Hsue Cheng, Chia-Pang Chan, Jun-He Yang
The issue of financial distress prediction plays an important and challenging research topic in the financial field. Currently, there have been many methods for predicting firm bankruptcy and financial crisis, including the artificial intelligence and the traditional statistical methods, and the past studies have shown that the prediction result of the artificial intelligence method is better than the traditional statistical method. Financial statements are quarterly reports; hence, the financial crisis of companies is seasonal time-series data, and the attribute data affecting the financial distress of companies is nonlinear and nonstationary time-series data with fluctuations...
2018: Computational Intelligence and Neuroscience
https://www.readbyqxmd.com/read/29737828/light-activated-ros-responsive-nanoplatform-co-delivering-apatinib-and-doxorubicin-for-enhanced-chemo-photodynamic-therapy-of-multidrug-resistant-tumors
#2
Xiao Wei, Lingqiao Liu, Xing Guo, Yi Wang, Jingya Zhao, Shaobing Zhou
Cancer chemotherapy faces the problem of the multidrug resistance (MDR) of tumor cells, which is a puzzling issue that leads to treatment failure. To address it, an innovative approach is proposed to construct a light-activated reactive oxygen species (ROS)-responsive nanoplatform based on a protoporphyrin (PpIX)-conjugated and dual chemotherapeutics-loaded polymer micelle. This system combines chemotherapy and photodynamic therapy (PDT) to defeat the MDR of tumors. Such an intelligent nanocarrier can prolong the blood circulation due to the negatively charged polysaccharide component of chondroitin sulfate (CS) and subsequently being selectively internalized by DOX-resistant human breast cancer MCF-7 cells (MCF-7/ADR)...
May 8, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29734793/fast-sparse-coding-for-range-data-denoising-with-sparse-ridges-constraint
#3
Zhi Gao, Mingjie Lao, Yongsheng Sang, Fei Wen, Bharath Ramesh, Ruifang Zhai
Light detection and ranging (LiDAR) sensors have been widely deployed on intelligent systems such as unmanned ground vehicles (UGVs) and unmanned aerial vehicles (UAVs) to perform localization, obstacle detection, and navigation tasks. Thus, research into range data processing with competitive performance in terms of both accuracy and efficiency has attracted increasing attention. Sparse coding has revolutionized signal processing and led to state-of-the-art performance in a variety of applications. However, dictionary learning, which plays the central role in sparse coding techniques, is computationally demanding, resulting in its limited applicability in real-time systems...
May 6, 2018: Sensors
https://www.readbyqxmd.com/read/29734623/prognoses-of-diameter-and-height-of-trees-of-eucalyptus-using-artificial-intelligence
#4
Giovanni Correia Vieira, Adriano Ribeiro de Mendonça, Gilson Fernandes da Silva, Sidney Sára Zanetti, Mayra Marques da Silva, Alexandre Rosa Dos Santos
Models of individual trees are composed of sub-models that generally estimate competition, mortality, and growth in height and diameter of each tree. They are usually adopted when we want more detailed information to estimate forest multiproduct. In these models, estimates of growth in diameter at 1.30m above the ground (DBH) and total height (H) are obtained by regression analysis. Recently, artificial intelligence techniques (AIT) have been used with satisfactory performance in forest measurement. Therefore, the objective of this study was to evaluate the performance of two AIT, artificial neural networks and adaptive neuro-fuzzy inference system, to estimate the growth in DBH and H of eucalyptus trees...
April 1, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29611291/multistimuli-responsive-core-shell-nanoplatform-constructed-from-fe-3-o-4-mof-equipped-with-pillar-6-arene-nanovalves
#5
Ming-Xue Wu, Jia Gao, Fang Wang, Jie Yang, Nan Song, Xiaoyu Jin, Peng Mi, Jian Tian, Jiayan Luo, Feng Liang, Ying-Wei Yang
An intelligent theranostic nanoplatform based on nanovalve operated metal-organic framework (MOF) core-shell hybrids, incorporating tumorous microenvironment-triggered drug release, magnetic resonance imaging (MRI) guidance, sustained release, and effective chemotherapy in one pot is reported. The core-shell hybrids are constructed by an in situ growth method, in which Fe3 O4 particles with superior abilities of MRI and magnetic separation form the core and UiO-66 MOF with high loading capacity compose the shell, and then are surface-installed with pillararene-based pseudorotaxanes as tightness-adjustable nanovalves...
April 3, 2018: Small
https://www.readbyqxmd.com/read/29577971/can-we-accelerate-medicinal-chemistry-by-augmenting-the-chemist-with-big-data-and-artificial-intelligence
#6
REVIEW
Edward J Griffen, Alexander G Dossetter, Andrew G Leach, Shane Montague
AI comes to lead optimization: medicinal chemistry in all disease areas can be accelerated by exploiting our pre-competitive knowledge in an unbiased way.
March 22, 2018: Drug Discovery Today
https://www.readbyqxmd.com/read/29546896/oxygen-vacancy-migration-diffusion-induced-synaptic-plasticity-in-a-single-titanate-nanobelt
#7
Ming Xiao, Daozhi Shen, Kevin P Musselman, Walter W Duley, Y Norman Zhou
Neuromorphic computational systems that emulate biological synapses in the human brain are fundamental in the development of artificial intelligence protocols beyond the standard von Neumann architecture. Such systems require new types of building blocks, such as memristors that access a quasi-continuous and wide range of conductive states, which is still an obstacle for the realization of high-efficiency and large-capacity learning in neuromorphoric simulation. Here, we introduce hydrogen and sodium titanate nanobelts, the intermediate products of hydrothermal synthesis of TiO2 nanobelts, to emulate the synaptic behavior...
March 16, 2018: Nanoscale
https://www.readbyqxmd.com/read/29544306/b1-b2-phase-transition-mechanism-and-pathway-of-pbs-under-pressure
#8
Adebayo A Adeleke, Yansun Yao
Experimental studies at finite Pressure-Temperature (P-T) conditions and a theoretical study at 0 K of the phase transition in lead sulphide (PbS) have been inconclusive. Many studies that have been done to understand structural transformation in PbS can broadly be classified into two main ideological streams-one with Pnma and another with Cmcm orthorhombic intermediate phase. To foster better understanding of this phenomenon, we present the result of the first-principles study of phase transition in PbS at finite temperature...
March 14, 2018: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29526014/judaism-as-a-group-evolutionary-strategy-a-critical-analysis-of-kevin-macdonald-s-theory
#9
Nathan Cofnas
MacDonald argues that a suite of genetic and cultural adaptations among Jews constitutes a "group evolutionary strategy." Their supposed genetic adaptations include, most notably, high intelligence, conscientiousness, and ethnocentrism. According to this thesis, several major intellectual and political movements, such as Boasian anthropology, Freudian psychoanalysis, and multiculturalism, were consciously or unconsciously designed by Jews to (a) promote collectivism and group continuity among themselves in Israel and the diaspora and (b) undermine the cohesion of gentile populations, thus increasing the competitive advantage of Jews and weakening organized gentile resistance (i...
June 2018: Human Nature: An Interdisciplinary Biosocial Perspective
https://www.readbyqxmd.com/read/29405194/-the-significance-of-student-competitions-for-the-development-of-motivation-for-education-and-the-acquisition-of-professional-competences-in-the-students-the-department-of-forensic-medical-expertise-of-the-sechenovsky-university
#10
Yu I Pigolkin, Yu V Lomakin, E N Leonova
Russia joined the Bologna process in 2003 and since that time has become integrated into the unified European educational space. The key element of the new form of the higher education process is the self-guided unsupervised work of the students. Motivation is needed to promote the involvement of the students in the educational process which implies the necessity of the goal-oriented initiative for the acquisition of professional knowledge and practical experience in the field of forensic medicine. To achieve this goal, the Department of Forensic Medicine of I...
2018: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/29404491/remodeling-the-model-for-end-stage-liver-disease-for-predicting-mortality-risk-in-critically-ill-patients-with-cirrhosis-and-acute-kidney-injury
#11
Xiao-Dong Zhou, Qin-Fen Chen, Dan-Qin Sun, Chen-Fei Zheng, Dong-Jie Liang, Jian Zhou, Song-Jie Wang, Wen-Yue Liu, Sven Van Poucke, Xiao-Dong Wang, Ke-Qing Shi, Wei-Jian Huang, Ming-Hua Zheng
Serum creatinine measurement demonstrates a poor specificity and sensitivity for the early diagnosis of acute kidney injury (AKI) in patients with cirrhosis. The existing model for end-stage liver disease (MELD) score reveals multiple pitfalls in critically ill patients with cirrhosis and acute kidney injury (CAKI). The aim of this study was to re-evaluate the role of creatinine values in the existing MELD score and to develop a novel score for CAKI, named the "acute kidney injury-model for end-stage liver disease score" (AKI-MELD score)...
October 2017: Hepatology communications
https://www.readbyqxmd.com/read/29341027/developing-deep-learning-applications-for-life-science-and-pharma-industry
#12
Daniel Siegismund, Vasily Tolkachev, Stephan Heyse, Beate Sick, Oliver Duerr, Stephan Steigele
Deep Learning has boosted artificial intelligence over the past 5 years and is seen now as one of the major technological innovation areas, predicted to replace lots of repetitive, but complex tasks of human labor within the next decade. It is also expected to be 'game changing' for research activities in pharma and life sciences, where large sets of similar yet complex data samples are systematically analyzed. Deep learning is currently conquering formerly expert domains especially in areas requiring perception, previously not amenable to standard machine learning...
January 16, 2018: Drug Research
https://www.readbyqxmd.com/read/29330442/competition-among-the-attentional-networks-due-to-resource-reduction-in-tibetan-indigenous-residents-evidence-from-event-related-potentials
#13
Delong Zhang, Xinjuan Zhang, Hailin Ma, Yan Wang, Huifang Ma, Ming Liu
This study used the attention network test (ANT) to evaluate the alerting, orienting, and executive network efficiencies of attention related to indigenous residents who were born and raised until early adulthood in different high-altitude areas (2900-m, 3700-m, and 4200-m) at the same location (3700-m) where these residents had been living for approximately 2 years in Tibet. We further applied the event-related potential (ERP) method to identify the underlying neurophysiological basis. Based on the ANT, we found that, in the 4200-m residents, executive function was increased but the orienting function was decreased, and the executive and orienting network scores were oppositely correlated...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29286057/notable-licensing-deals-in-the-biopharma-industry-in-the-third-quarter-of-2017
#14
P D'Souza
During the third quarter of 2017, Cortellis Competitive Intelligence registered 949 new deals (excluding mergers and acquisitions) added as part of its ongoing coverage of pharmaceutical licensing activity compared to 1,007 in Q2 this year and 1,023 in Q3 the previous year.
October 2017: Drugs of Today
https://www.readbyqxmd.com/read/29283966/undertriage-in-trauma-does-an-organized-trauma-network-capture-the-major-trauma-victim-a-statewide-analysis
#15
Michael A Horst, Shreya Jammula, Brian W Gross, Alan D Cook, Eric H Bradburn, Juliet Altenburg, Danielle Von Nieda, Madison Morgan, Frederick B Rogers
BACKGROUND: Proper triage of critically injured trauma patients to accredited trauma centers (TCs) is essential for survival and patient outcomes. We sought to determine the percentage of patients meeting trauma criteria who received care at non-TCs (NTCs) within the statewide trauma system that exists in the state of Pennsylvania. We hypothesized that a substantial proportion of the trauma population would be undertriaged to NTCs with undertriage rates (UTR) decreasing with increasing severity of injury...
March 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29238546/receptor-uptake-arrays-for-vitamin-b-12-siderophores-and-glycans-shape-bacterial-communities
#16
REVIEW
Steven A Frank
Molecular variants of vitamin B12 , siderophores, and glycans occur. To take up variant forms, bacteria may express an array of receptors. The gut microbe Bacteroides thetaiotaomicron has three different receptors to take up variants of vitamin B12 and 88 receptors to take up various glycans. The design of receptor arrays reflects key processes that shape cellular evolution. Competition may focus each species on a subset of the available nutrient diversity. Some gut bacteria can take up only a narrow range of carbohydrates, whereas species such as B...
December 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/29232907/a-game-theory-based-incentive-framework-for-an-intelligent-traffic-system-as-part-of-a-smart-city-initiative
#17
Haibo Mei, Stefan Poslad, Shuang Du
Intelligent Transportation Systems (ITSs) can be applied to inform and incentivize travellers to help them make cognizant choices concerning their trip routes and transport modality use for their daily travel whilst achieving more sustainable societal and transport authority goals. However, in practice, it is challenging for an ITS to enable incentive generation that is context-driven and personalized, whilst supporting multi-dimensional travel goals. This is because an ITS has to address the situation where different travellers have different travel preferences and constraints for route and modality, in the face of dynamically-varying traffic conditions...
December 11, 2017: Sensors
https://www.readbyqxmd.com/read/29206159/energy-management-in-smart-cities-based-on-internet-of-things-peak-demand-reduction-and-energy-savings
#18
Chinmaya Mahapatra, Akshaya Kumar Moharana, Victor C M Leung
Around the globe, innovation with integrating information and communication technologies (ICT) with physical infrastructure is a top priority for governments in pursuing smart, green living to improve energy efficiency, protect the environment, improve the quality of life, and bolster economy competitiveness. Cities today faces multifarious challenges, among which energy efficiency of homes and residential dwellings is a key requirement. Achieving it successfully with the help of intelligent sensors and contextual systems would help build smart cities of the future...
December 5, 2017: Sensors
https://www.readbyqxmd.com/read/29168131/the-relationship-between-spiritual-intelligence-and-aggression-among-elite-wrestlers-in-hamadan-province-of-iran
#19
Javad Karimi, Mohammad Mohammadi
The purpose of this study was to investigate the relationship between spiritual intelligence and aggression among elite wrestlers of adolescent age group. The present study was descriptive of correlation type in terms of method and applied in terms of purpose. The population of this research was the elite wrestlers of adolescents age group aged 14-17 (mean and SD of 15.27 ± 1.33) using the convenient sampling method for adolescent wrestling teams of Hamedan clubs selected as samples. To measure variables, King's spiritual intelligence scale and Bass and Perry aggression questionnaire were used...
November 22, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/29161013/intelligent-peptide-gathering-mechanical-arm-tames-wild-trojan-horse-peptides-for-the-controlled-delivery-of-cancer-nanotherapeutics
#20
Nian-Qiu Shi, Yan Li, Yong Zhang, Nan Shen, Ling Qi, Shu-Ran Wang, Xian-Rong Qi
Cell-penetrating peptides (CPPs), also called "Trojan-Horse" peptides, have been used for facilitating intracellular delivery of numerous diverse cargoes and even nanocarriers. However, the lack of targeting specificity ("wildness" or nonselectivity) of CPP-nanocarriers remains an intractable challenge for many in vivo applications. In this work, we used an intelligent "peptide-gathering mechanical arm" (Int PMA) to curb CPPs' wildness and enhance the selectivity of R9 -liposome-based cargo delivery for tumor targeting...
December 6, 2017: ACS Applied Materials & Interfaces
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