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https://www.readbyqxmd.com/read/28268933/on-efficient-meta-filtering-of-big-data
#1
Keith Dillon, Yu-Ping Wang
There is an explosion in the number of new approaches being developed for extracting information from biological data, creating a need for intelligent ways to utilize so many methods. We take a perspective based on viewing methods as filters which reject undesired data and which may have complementary and redundant performance. We consider approaches for efficiently combining such filters. We provide quantitative strategies for choosing which filters to use and the best order to apply them, based on viewing each filter as a coordinate transformation on performance metrics...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227139/on-efficient-meta-filtering-of-big-data
#2
Keith Dillon, Yu-Ping Wang, Keith Dillon, Yu-Ping Wang, Yu-Ping Wang, Keith Dillon
There is an explosion in the number of new approaches being developed for extracting information from biological data, creating a need for intelligent ways to utilize so many methods. We take a perspective based on viewing methods as filters which reject undesired data and which may have complementary and redundant performance. We consider approaches for efficiently combining such filters. We provide quantitative strategies for choosing which filters to use and the best order to apply them, based on viewing each filter as a coordinate transformation on performance metrics...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28188882/intelligibility-in-speech-maskers-with-a-binaural-cochlear-implant-sound-coding-strategy-inspired-by-the-contralateral-medial-olivocochlear-reflex
#3
Enrique A Lopez-Poveda, Almudena Eustaquio-Martín, Joshua S Stohl, Robert D Wolford, Reinhold Schatzer, José M Gorospe, Santiago Santa Cruz Ruiz, Fernando Benito, Blake S Wilson
We have recently proposed a binaural cochlear implant (CI) sound processing strategy inspired by the contralateral medial olivocochlear reflex (the MOC strategy) and shown that it improves intelligibility in steady-state noise (Lopez-Poveda et al., 2016, Ear Hear 37:e138-e148). The aim here was to evaluate possible speech-reception benefits of the MOC strategy for speech maskers, a more natural type of interferer. Speech reception thresholds (SRTs) were measured in six bilateral and two single-sided deaf CI users with the MOC strategy and with a standard (STD) strategy...
February 7, 2017: Hearing Research
https://www.readbyqxmd.com/read/28174613/banknote-recognition-investigating-processing-and-cognition-framework-using-competitive-neural-network
#4
Oyebade K Oyedotun, Adnan Khashman
Humans are apt at recognizing patterns and discovering even abstract features which are sometimes embedded therein. Our ability to use the banknotes in circulation for business transactions lies in the effortlessness with which we can recognize the different banknote denominations after seeing them over a period of time. More significant is that we can usually recognize these banknote denominations irrespective of what parts of the banknotes are exposed to us visually. Furthermore, our recognition ability is largely unaffected even when these banknotes are partially occluded...
February 2017: Cognitive Neurodynamics
https://www.readbyqxmd.com/read/28170227/analyte-responsive-hydrogels-intelligent-materials-for-biosensing-and-drug-delivery
#5
Heidi R Culver, John R Clegg, Nicholas A Peppas
Nature has mastered the art of molecular recognition. For example, using synergistic non-covalent interactions, proteins can distinguish between molecules and bind a partner with incredible affinity and specificity. Scientists have developed, and continue to develop, techniques to investigate and better understand molecular recognition. As a consequence, analyte-responsive hydrogels that mimic these recognitive processes have emerged as a class of intelligent materials. These materials are unique not only in the type of analyte to which they respond but also in how molecular recognition is achieved and how the hydrogel responds to the analyte...
February 7, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28110077/informational-masking-and-the-effects-of-differences-in-fundamental-frequency-and-fundamental-frequency-contour-on-phonetic-integration-in-a-formant-ensemble
#6
Robert J Summers, Peter J Bailey, Brian Roberts
This study explored the effects on speech intelligibility of across-formant differences in fundamental frequency (ΔF0) and F0 contour. Sentence-length speech analogues were presented dichotically (left = F1 + F3; right = F2), either alone or-because competition usually reveals grouping cues most clearly-accompanied in the left ear by a competitor for F2 (F2C) that listeners must reject to optimize recognition. F2C was created by inverting the F2 frequency contour. In experiment 1, all left-ear formants shared the same constant F0 and ΔF0F2 was 0 or ±4 semitones...
January 18, 2017: Hearing Research
https://www.readbyqxmd.com/read/28081117/interplay-between-public-attention-and-public-emotion-toward-multiple-social-issues-on-twitter
#7
Tai-Quan Peng, Guodao Sun, Yingcai Wu
This study aims to elucidate the intricate interplay between public attention and public emotion toward multiple social issues. A theoretical framework is developed based on three perspectives including endogenous affect hypothesis, affect transfer hypothesis, and affective intelligence theory. Large-scale longitudinal data with 265 million tweets on five social issues are analyzed using a time series analytical approach. Public attention on social issues can influence public emotion on the issue per se. Social issues interact with one another to attract public attention in both cooperative and competitive ways...
2017: PloS One
https://www.readbyqxmd.com/read/28073247/tuning-for-visible-fluorescence-and-near-infrared-phosphorescence-on-a-unimolecular-mechanically-sensitive-platform-via-adjustable-ch-%C3%AF-interaction
#8
Hongwei Wu, Pei Zhao, Xin Li, Wenbo Chen, Hans Ågren, Qing Zhang, Liangliang Zhu
CH-π interaction-assisted alignment of organic conjugated systems has played an important role to regulate molecular electronic and photophysical properties, whereas harnessing such a smart noncovalent interaction into the tuning of unimolecular complex emissive bands covering a wide spectral region remains a challenging research topic. Since the tuning for visible and near-infrared emissive properties in a single π-functional platform relates to its multicolor luminescent behaviors and potential superior application in analysis, bioimaging, and sensing, herein, we report a proportional control of the singlet and triplet emissions that cover visible and near-infrared spectral regions, respectively, can be straightforwardly achieved by CH-π interaction-assisted self-assembly at the unimolecular level...
February 1, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28055847/show-and-tell-lessons-learned-from-the-2015-mscoco-image-captioning-challenge
#9
Oriol Vinyals, Alexander Toshev, Samy Bengio, Dumitru Erhan
Automatically describing the content of an image is a fundamental problem in artificial intelligence that connects computer vision and natural language processing. In this paper, we present a generative model based on a deep recurrent architecture that combines recent advances in computer vision and machine translation and that can be used to generate natural sentences describing an image. The model is trained to maximize the likelihood of the target description sentence given the training image. Experiments on several datasets show the accuracy of the model and the fluency of the language it learns solely from image descriptions...
July 7, 2016: IEEE Transactions on Pattern Analysis and Machine Intelligence
https://www.readbyqxmd.com/read/28039373/a-model-of-the-superior-colliculus-predicts-fixation-locations-during-scene-viewing-and-visual-search
#10
Hossein Adeli, Françoise Vitu, Gregory J Zelinsky
Modern computational models of attention predict fixations using saliency maps and target maps, which prioritize locations for fixation based on feature contrast and target goals, respectively. But whereas many such models are biologically plausible, none have looked to the oculomotor system for design constraints or parameter specification. Conversely, although most models of saccade programming are tightly coupled to underlying neurophysiology, none have been tested using real-world stimuli and tasks. We combined the strengths of these two approaches in MASC, a model of attention in the superior colliculus (SC) that captures known neurophysiological constraints on saccade programming...
February 8, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27998135/luminescent-poly-vinyl-alcohol-carbon-quantum-dots-composites-with-tunable-water-induced-shape-memory-behavior-in-different-ph-and-temperature-environments
#11
Guanghui Yang, Xuejuan Wan, Yijin Liu, Rui Li, Yikun Su, Xierong Zeng, Jiaoning Tang
Luminescent water-induced shape memory polymer (SMP) composites with tunable shape recovery rate are developed by blending poly(vinyl alcohol) (PVA) and carbon quantum dots (CQDs). The oxygen and active hydrogen-rich CQDs can serve as extra physical cross-linking points in PVA via strong hydrogen bonding interaction, which largely improves the shape memory performances of PVA. At room temperature, water can successfully actuate the shape recovery of deformed PVA/CQDs composite. It is demonstrated that this water-induced shape recovery is mainly attributed to the plasticizing effect of water and its competitive hydrogen bonding...
December 21, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27933297/exhibitionist-eating-who-wins-eating-competitions
#12
Brian Wansink, Kevin M Kniffin
OBJECTIVE: How and why does competition and spectator involvement influence eating behaviors? The primary objective of this article is to explore the nature of competitive eating with the goal of identifying implications for other social situations. DESIGN: Study 1 investigated how many chicken wings were eaten by men and women in a 30-min eating competition when cheering spectators either were or were not present (compared to a control condition). The second study sought to explain Study 1's findings through a survey of 93 students who rated male or female competitive eaters (in randomized order) based on intelligence, attractiveness, health, strength, and how romantic they expected the eaters to be...
2016: Frontiers in Nutrition
https://www.readbyqxmd.com/read/27910965/notable-deals-in-the-pharmaceutical-industry-in-the-third-quarter-of-2016
#13
E Cruces
During the third quarter of 2016, Cortellis Competitive Intelligence had 865 new deals added as part of its ongoing coverage of pharmaceutical licensing activity. This figure shows similar deal activity compared with the same quarter of 2015 (934), and 21% less than the previous quarter, although they had similar disclosed financial sizes in comparison with the first half of 2016. This article will focus on a number of the most valuable and notable deals forged during the quarter, as well as a selection of deals from some of the most prolific deal makers...
October 2016: Drugs of Today
https://www.readbyqxmd.com/read/27910739/overview-on-therapeutic-applications-of-microparticulate-drug-delivery-systems
#14
REVIEW
Swarna Bale, Amit Khurana, A Shiva Shankar Reddy, Mandip Singh, Chandraiah Godugu
Research in novel drug delivery systems is being explored competitively in order to attain maximum therapeutic effect while minimizing the adverse effects. Despite several advancements in pharmaceutical formulations, one of the major challenges still persisting is sustained drug release. Microencapsulation enacts as an intelligent approach with a strong therapeutic impact and is in demand globally in medical technology due to its specific and attractive properties, including biocompatibility, stability, target specificity, uniform encapsulation, better compliance, and controlled and sustained release patterns that are responsible for diminishing the toxicity and dosage frequency...
2016: Critical Reviews in Therapeutic Drug Carrier Systems
https://www.readbyqxmd.com/read/27881894/competition-related-factors-directly-influence-preferences-for-facial-cues-of-dominance-in-allies
#15
Christopher D Watkins, Benedict C Jones
ABSTRACT: Alliance formation is a critical dimension of social intelligence in political, social and biological systems. As some allies may provide greater "leverage" than others during social conflict, the cognitive architecture that supports alliance formation in humans may be shaped by recent experience, for example in light of the outcomes of violent or non-violent forms intrasexual competition. Here we used experimental priming techniques to explore this issue. Consistent with our predictions, while men's preferences for dominant allies strengthened following losses (compared to victories) in violent intrasexual contests, women's preferences for dominant allies weakened following losses (compared to victories) in violent intrasexual contests...
2016: Behavioral Ecology and Sociobiology
https://www.readbyqxmd.com/read/27815130/informational-masking-and-the-effects-of-differences-in-fundamental-frequency-and-fundamental-frequency-contour-on-phonetic-integration-in-a-formant-ensemble
#16
Robert J Summers, Peter J Bailey, Brian Roberts
This study explored the effects on speech intelligibility of across-formant differences in fundamental frequency (ΔF0) and F0 contour. Sentence-length speech analogues were presented dichotically (left = F1+F3; right = F2), either alone or-because competition usually reveals grouping cues most clearly-accompanied in the left ear by a competitor for F2 (F2C) that listeners must reject to optimize recognition. F2C was created by inverting the F2 frequency contour. In experiment 1, all left-ear formants shared the same constant F0 and ΔF0F2 was 0 or ±4 semitones...
November 1, 2016: Hearing Research
https://www.readbyqxmd.com/read/27762047/a-responsive-battery-with-controlled-energy-release
#17
Xiaopeng Wang, Jian Gao, Zhihua Cheng, Nan Chen, Liangti Qu
A new type of responsive battery with the fascinating feature of pressure perceptibility has been developed, which can spontaneously, timely and reliably control the power outputs (e.g., current and voltage) in response to pressure changes. The device design is based on the structure of the Zn-air battery, in which graphene-coated sponge serves as pressure-sensitive air cathode that endows the whole system with the capability of self-controlled energy release. The responsive batteries exhibit superior battery performance with high open-circuit voltage (1...
November 14, 2016: Angewandte Chemie
https://www.readbyqxmd.com/read/27757452/spatial-organization-based-reciprocal-switching-of-enzyme-free-nucleic-acid-circuits
#18
Yidan Tang, Zhentong Zhu, Baiyang Lu, Bingling Li
We report a new nucleic acid sensing strategy through an intelligent design of spatial organization based reciprocal switching of catalytic hairpin assembly (CHA). The so-called SORS-CHA not only turns a well-designed CHA circuit into a relatively universal detector for any targeting sequence, but also guarantees a much enhanced signal resolution and a believability to minimize the misreading induced by unexpected signal drifts. With more trustworthy results, but a simpler sequence design, nucleic acid circuits could become competitive in real-world applications...
October 19, 2016: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/27757379/tourism-guide-cloud-service-quality-what-actually-delights-customers
#19
Shu-Ping Lin, Chen-Lung Yang, Han-Chung Pi, Thao-Minh Ho
BACKGROUND: The emergence of advanced IT and cloud services has beneficially supported the information-intensive tourism industry, simultaneously caused extreme competitions in attracting customers through building efficient service platforms. On response, numerous nations have implemented cloud platforms to provide value-added sightseeing information and personal intelligent service experiences. Despite these efforts, customers' actual perspectives have yet been sufficiently understood...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27722214/notable-deals-in-the-pharmaceutical-industry-in-the-second-quarter-of-2016
#20
P D'Souza
During the second quarter of 2016, Cortellis Competitive Intelligence had 1,014 new deals added as part of its ongoing coverage of pharmaceutical licensing activity. This was on par with the last quarter (1,011) and a substantial increase on the same quarter for the previous 1 year (659). This article will focus on highlighting a number of the most valuable and notable deals forged during the quarter, as well as a selection of deals from some of the most prolific deal makers. An update on milestone, options and terminated deals of significance will also be presented, along with an early outlook on the next quarter's pharmaceutical licensing activity...
August 2016: Drugs of Today
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