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https://www.readbyqxmd.com/read/28916478/a-retrospective-study-of-pulseless-electrical-activity-bedside-ultrasound-identifies-interventions-during-resuscitation-associated-with-improved-survival-to-hospital-admission-a-reason-study
#1
Romolo Gaspari, Anthony Weekes, Srikar Adhikari, Vicki Noble, Jason T Nomura, Daniel Theodoro, Michael Woo, Paul Atkinson, David Blehar, Samuel Brown, Terrell Caffery, Emily Douglass, Jacqueline Fraser, Christine Haines, Samuel Lam, Michael Lanspa, Margaret Lewis, Otto Liebmann, Alexander Limkakeng, Fernando Lopez, Elke Platz, Michelle Mendoza, Hal Minnigan, Christopher Moore, Joseph Novik, Louise Rang, Will Scruggs, Christopher Raio
OBJECTIVE: Our objective was to determine whether organized or disorganized cardiac activity is associated with increased survival in patients who present in pulseless electrical activity (PEA) treated with either 1) standard advanced cardiac life support (ACLS) medications or 2) other interventions. METHODS: This was a secondary analysis of a prospective, multi-center observational study utilizing ultrasound in out-of-hospital or inemergency department PEA arrest...
September 12, 2017: Resuscitation
https://www.readbyqxmd.com/read/28914401/2017-hrs-ehra-ecas-aphrs-solaece-expert-consensus-statement-on-catheter-and-surgical-ablation-of-atrial-fibrillation-executive-summary
#2
Hugh Calkins, Gerhard Hindricks, Riccardo Cappato, Young-Hoon Kim, Eduardo B Saad, Luis Aguinaga, Joseph G Akar, Vinay Badhwar, Josep Brugada, John Camm, Peng-Sheng Chen, Shih-Ann Chen, Mina K Chung, Jens Cosedis Nielsen, Anne B Curtis, D Wyn Davies, John D Day, André d'Avila, N M S Natasja de Groot, Luigi Di Biase, Mattias Duytschaever, James R Edgerton, Kenneth A Ellenbogen, Patrick T Ellinor, Sabine Ernst, Guilherme Fenelon, Edward P Gerstenfeld, David E Haines, Michel Haissaguerre, Robert H Helm, Elaine Hylek, Warren M Jackman, Jose Jalife, Jonathan M Kalman, Josef Kautzner, Hans Kottkamp, Karl Heinz Kuck, Koichiro Kumagai, Richard Lee, Thorsten Lewalter, Bruce D Lindsay, Laurent Macle, Moussa Mansour, Francis E Marchlinski, Gregory F Michaud, Hiroshi Nakagawa, Andrea Natale, Stanley Nattel, Ken Okumura, Douglas Packer, Evgeny Pokushalov, Matthew R Reynolds, Prashanthan Sanders, Mauricio Scanavacca, Richard Schilling, Claudio Tondo, Hsuan-Ming Tsao, Atul Verma, David J Wilber, Teiichi Yamane
No abstract text is available yet for this article.
September 15, 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/28911131/addressing-challenges-to-human-health-in-the-anthropocene-epoch-an-overview-of-the-findings-of-the-rockefeller-lancet-commission-on-planetary-health
#3
Andy Haines
No abstract text is available yet for this article.
September 1, 2017: International Health
https://www.readbyqxmd.com/read/28910248/parents-online-discussions-about-children-s-dental-caries-a-critical-content-analysis
#4
Avery Milne, Cynthia A Weijs, Rebecca J Haines-Saah, Lindsay McLaren
OBJECTIVES: Through an analysis of postings to an online parenting forum, we aimed to explore the many ways in which parents orient to (i.e., take up, challenge, re-articulate) information about child dental health in the context of their online interactions. Our analysis is anchored in Nettleton's theoretical work on dental authority and power, which we apply in a digital context. METHODS: We examined discussion threads from the public online forums on BabyCenter Canada...
September 14, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/28906233/marijuana-use-and-perceptions-of-risk-and-harm-a-survey-among-canadians-in-2016
#5
Eldon Spackman, Rebecca Haines-Saah, Vishva M Danthurebandara, Laura E Dowsett, Tom Noseworthy, Fiona M Clement
OBJECTIVES: To describe marijuana use by Canadians and their perceptions of risk and harm. DESIGN: A cross-sectional, structured, online and telephone survey. PARTICIPANTS: A nationally representative sample of Canadians. METHODS: This survey used random probability sampling and targeted respondents based on age, sex, region and their expected response rate. RESULTS: Of the 20% of respondents reporting marijuana use in the past 12 months, they were more likely to be younger and male...
August 2017: Healthcare Policy, Politiques de Santé
https://www.readbyqxmd.com/read/28904814/factors-impacting-perceived-safety-among-staff-working-on-mental-health-wards
#6
Alina Haines, Andrew Brown, Rhiannah McCabe, Michelle Rogerson, Richard Whittington
BACKGROUND: Safety at work is a core issue for mental health staff working on in-patient units. At present, there is a limited theoretical base regarding which factors may affect staff perceptions of safety. AIMS: This study attempted to identify which factors affect perceived staff safety working on in-patient mental health wards. METHOD: A cross-sectional design was employed across 101 forensic and non-forensic mental health wards, over seven National Health Service trusts nationally...
September 2017: BJPsych Open
https://www.readbyqxmd.com/read/28904673/mutations-in-rpob-and-katg-genes-of-multidrug-resistant-mycobacterium-tuberculosis-undetectable-using-genotyping-diagnostic-methods
#7
Faustinos Tatenda Takawira, Racheal Shamiso Dube Mandishora, Zephaniah Dhlamini, Ellen Munemo, Babill Stray-Pedersen
INTRODUCTION: Tuberculosis remains the leading causes of death worldwide with frequencies of mutations in rifampicin and isoniazid resistant Mycobacterium tuberculosis isolates varying according to geographical location. There is limited information in Zimbabwe on specific antibiotic resistance gene mutation patterns in MTB and hence, increased rate of discordant results and mortality due to inappropriate antibiotic prescriptions. The rpoB and katG genes molecular markers are used for detecting rifampicin and isoniazid resistance respectively...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28901173/cyclin-d2-is-a-critical-mediator-of-exercise-induced-cardiac-hypertrophy
#8
Stephen W Luckey, Chris D Haines, John P Konhilas, Elizabeth D Luczak, Antke Messmer-Kratzsch, Leslie A Leinwand
A number of signaling pathways underlying pathological cardiac hypertrophy have been identified. However, few studies have probed the functional significance of these signaling pathways in the context of exercise or physiological pathways. Exercise studies were performed on females from six different genetic mouse models that have been shown to exhibit alterations in pathological cardiac adaptation and hypertrophy. These include mice expressing constitutively active glycogen synthase kinase-3β (GSK-3βS9A), an inhibitor of CaMK II (AC3-I), both GSK-3βS9A and AC3-I (GSK-3βS9A/AC3-I), constitutively active Akt (myrAkt), mice deficient in MAPK/ERK kinase kinase-1 (MEKK1(-/-)), and mice deficient in cyclin D2 (cyclin D2(-/-))...
January 1, 2017: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28898465/polar-electrode-bridged-electroluminescent-displays-2d-sensors-remotely-communicating-optically
#9
Xiuru Xu, Dan Hu, Lijia Yan, Shaoli Fang, Clifton Shen, Yueh-Lin Loo, Yuan Lin, Carter S Haines, Na Li, Anvar A Zakhidov, Hong Meng, Ray H Baughman, Wei Huang
A novel geometry for electroluminescent devices, which does not require transparent electrodes for electrical input, is demonstrated, theoretically analyzed, and experimentally characterized. Instead of emitting light through a conventional electrode, light emission occurs through a polar liquid or solid and input electrical electrodes are coplanar, rather than stacked in a sandwich configuration. This new device concept is scalable and easily deployed for a range of modular alternating-current-powered electroluminescent light sources and light-emitting sensing devices...
September 12, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28889213/robotic-approach-to-resection-of-villous-adenoma-of-the-urachus-a-case-report-and-literature-review
#10
Annie Chen, Julio Chong, Quisheng Si, Kenneth Haines, Reza Mehrazin
Very few cases of villous adenomas of the bladder or urinary tract have been described. To our knowledge this is the first account of resection of an urachal villous adenoma via robotic laparoscopy, which is a safe and efficacious surgical approach. At this time, there is not enough evidence to suggest that progression of disease to carcinoma is the typical course. Nonetheless, follow-up cystoscopy is recommended after complete removal of the adenoma to monitor for recurrence. This case report reviews the current literature and describes a novel approach to treatment of this exceedingly rare entity...
September 9, 2017: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/28873592/statistical-interpretation-of-chromatic-indicators-in-correlation-to-phytochemical-profile-of-a-sulfur-dioxide-free-mulberry-morus-nigra-wine-submitted-to-non-thermal-maturation-processes
#11
William Tchabo, Yongkun Ma, Emmanuel Kwaw, Haining Zhang, Lulu Xiao, Maurice T Apaliya
The four different methods of color measurement of wine proposed by Boulton, Giusti, Glories and Commission International de l'Eclairage (CIE) were applied to assess the statistical relationship between the phytochemical profile and chromatic characteristics of sulfur dioxide-free mulberry (Morus nigra) wine submitted to non-thermal maturation processes. The alteration in chromatic properties and phenolic composition of non-thermal aged mulberry wine were examined, aided by the used of Pearson correlation, cluster and principal component analysis...
January 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/28872570/when-fever-leukocytosis-and-right-lower-quadrant-pain-is-not-appendicitis
#12
Jeanette Kurbedin, Lawrence Haines, Marla C Levine, Eitan Dickman
Mesenteric cystic lymphangioma (MCL) is an uncommon, benign, slow-growing abdominal tumor that is derived from the lymphatic vessels (World J Gastroenterol. 2012;18:6328-6332, Radiographics. 1994;14:729-737). It is most often diagnosed in the head and neck of affected children. Rarely, a lymphangioma can develop within the small bowel (Pan Afr Med J. 2012;12:7). The clinical presentation of patients with an abdominal MCL can range from asymptomatic to acute abdominal pain (J Korean Surg Soc. 2012;83:102-106)...
September 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28870693/therapeutic-targeting-of-taz-and-yap-by-dimethyl-fumarate-in-systemic-sclerosis-fibrosis
#13
Tetsuo Toyama, Agnieszka P Looney, Brendon M Baker, Lukasz Stawski, Paul Haines, Robert Simms, Aleksander D Szymaniak, Xaralabos Varelas, Maria Trojanowska
Systemic sclerosis (scleroderma, SSc) is a devastating fibrotic disease with few treatment options. Fumaric acid esters, including dimethyl fumarate (DMF, Tecfidera®) have shown therapeutic effects in several disease models, prompting us to determine whether DMF is effective as a treatment for SSc dermal fibrosis. We found that DMF blocks the pro-fibrotic effects of TGFβ in SSc skin fibroblasts. Mechanistically, we found that DMF treatment reduced nuclear localization of TAZ and YAP proteins via inhibition of PI3-K/Akt1 pathway...
September 1, 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/28854578/the-molecular-genetics-of-eye-diseases
#14
Jonathan L Haines, Val C Sheffield
No abstract text is available yet for this article.
August 1, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28853718/genetic-correlations-between-intraocular-pressure-blood-pressure-and-primary-open-angle-glaucoma-a-multi-cohort-analysis
#15
Hugues Aschard, Jae H Kang, Adriana I Iglesias, Pirro Hysi, Jessica N Cooke Bailey, Anthony P Khawaja, R Rand Allingham, Allison Ashley-Koch, Richard K Lee, Sayoko E Moroi, Murray H Brilliant, Gadi Wollstein, Joel S Schuman, John H Fingert, Donald L Budenz, Tony Realini, Terry Gaasterland, William K Scott, Kuldev Singh, Arthur J Sit, Robert P Igo, Yeunjoo E Song, Lisa Hark, Robert Ritch, Douglas J Rhee, Vikas Gulati, Shane Haven, Douglas Vollrath, Donald J Zack, Felipe Medeiros, Robert N Weinreb, Ching-Yu Cheng, Daniel I Chasman, William G Christen, Margaret A Pericak-Vance, Yutao Liu, Peter Kraft, Julia E Richards, Bernard A Rosner, Michael A Hauser, Caroline C W Klaver, Cornelia M vanDuijn, Jonathan Haines, Janey L Wiggs, Louis R Pasquale
Primary open-angle glaucoma (POAG) is the most common chronic optic neuropathy worldwide. Epidemiological studies show a robust positive relation between intraocular pressure (IOP) and POAG and modest positive association between IOP and blood pressure (BP), while the relation between BP and POAG is controversial. The International Glaucoma Genetics Consortium (n=27 558), the International Consortium on Blood Pressure (n=69 395), and the National Eye Institute Glaucoma Human Genetics Collaboration Heritable Overall Operational Database (n=37 333), represent genome-wide data sets for IOP, BP traits and POAG, respectively...
August 30, 2017: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/28851255/comparison-of-radial-access-versus-femoral-access-with-the-use-of-a-vascular-closure-device-for-the-prevention-of-vascular-complications-and-mortality-after-percutaneous-coronary-intervention
#16
Arno Téblick, Wies Vanderbruggen, Tom Vandendriessche, Johan Bosmans, Steven Els Frans Haine, Hielko Miljoen, Vincent Segers, Kristien Wouters, Christiaan Vrints, Marc J Claeys
BACKGROUND: Radial access (RA) and vascular closure devices (VCD) have been shown to be superior to transfemoral access (TFA) with regard to the prevention of vascular complications after percutaneous coronary intervention (PCI). OBJECTIVE: The present study evaluates whether RA is associated with less vascular complications and a lower mortality than VCD. METHODS: A total of 6999 consecutive PCI patients were studied through a single-centre prospective registry from January 2011 to August 2015...
August 29, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28844361/a-randomized-controlled-study-comparing-internet-based-cognitive-behavioral-therapy-and-counselling-by-standard-care-for-fear-of-birth-a-study-protocol
#17
Elin Ternström, Ingegerd Hildingsson, Helen Haines, Annika Karlström, Örjan Sundin, Johanna Ekdahl, Birgitta Segeblad, Birgitta Larsson, Elisabet Rondung, Christine Rubertsson
Fear of birth is a concern that requires evidence based treatment. The aim of this study is to present the protocol of a randomized controlled multi-center trial to compare internet-based cognitive therapy with counseling as standard care for pregnant women reporting fear of birth. Participants will be recruited in mid-pregnancy. Women who score 60 or above on the Fear of Birth Scale will be offered to participate in this study. Data will be collected by questionnaires including validated instruments at baseline and follow-ups at gestational weeks 30 and 36, two months and one year after birth...
October 2017: Sexual & Reproductive Healthcare: Official Journal of the Swedish Association of Midwives
https://www.readbyqxmd.com/read/28839275/fitness-consequences-of-peak-reproductive-effort-in-a-resource-pulse-system
#18
Anni Hämäläinen, Andrew G McAdam, Ben Dantzer, Jeffrey E Lane, Jessica A Haines, Murray M Humphries, Stan Boutin
The age trajectory of reproductive performance of many iteroparous species features an early - life increase in performance followed by a late - life senescent decline. The largest contribution of lifetime reproductive success is therefore gained at the age at which reproductive performance peaks. Using long term data on North American red squirrels we show that the environmental conditions individuals encountered could cause variation among individuals in the "height" and timing of this peak, contributing to life history variation and fitness in this population that experiences irregular resource pulses...
August 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28839100/platelet-clec-2-protects-against-lung-injury-via-effects-of-its-ligand-podoplanin-on-inflammatory-alveolar-macrophages-in-the-mouse
#19
Sian Lax, Julie Rayes, Surasak Wichaiyo, Elizabeth J Haining, Kate Lowe, Beata Grygielska, Ryan Laloo, Per Flodby, Zea Borok, Edward D Crandall, David Thickett, Steve P Watson
There is no therapeutic intervention proven to prevent the acute respiratory syndrome (ARDS). Novel mechanistic insights into the pathophysiology of ARDS are therefore required. Platelets are implicated in regulating many of the pathogenic processes which occur during ARDS, however the mechanisms remain elusive. The platelet receptor C-type lectin-like 2 (CLEC-2) has been shown to regulate vascular integrity at sites of acute inflammation. Therefore, the purpose of this study was to establish the role of CLEC-2 and its ligand podoplanin in a mouse model of ARDS...
August 24, 2017: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/28839068/harvesting-electrical-energy-from-carbon-nanotube-yarn-twist
#20
Shi Hyeong Kim, Carter S Haines, Na Li, Keon Jung Kim, Tae Jin Mun, Changsoon Choi, Jiangtao Di, Young Jun Oh, Juan Pablo Oviedo, Julia Bykova, Shaoli Fang, Nan Jiang, Zunfeng Liu, Run Wang, Prashant Kumar, Rui Qiao, Shashank Priya, Kyeongjae Cho, Moon Kim, Matthew Steven Lucas, Lawrence F Drummy, Benji Maruyama, Dong Youn Lee, Xavier Lepró, Enlai Gao, Dawood Albarq, Raquel Ovalle-Robles, Seon Jeong Kim, Ray H Baughman
Mechanical energy harvesters are needed for diverse applications, including self-powered wireless sensors, structural and human health monitoring systems, and the extraction of energy from ocean waves. We report carbon nanotube yarn harvesters that electrochemically convert tensile or torsional mechanical energy into electrical energy without requiring an external bias voltage. Stretching coiled yarns generated 250 watts per kilogram of peak electrical power when cycled up to 30 hertz, as well as up to 41.2 joules per kilogram of electrical energy per mechanical cycle, when normalized to harvester yarn weight...
August 25, 2017: Science
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