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Forensic Medicine

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https://www.readbyqxmd.com/read/28432962/gc-ms-quantitative-analysis-of-black-market-pharmaceutical-products-containing-anabolic-androgenic-steroids-seized-by-the-brazilian-federal-police
#1
Diana Brito da Justa Neves, Eloisa Dutra Caldas
The use of counterfeit or substandard medicines can have an important health impact, resulting in therapeutic failure, be toxic or even cause death. Anabolic steroids are a frequent target for counterfeiters worldwide, being the second most frequent counterfeited class in Brazil. The aims of this work were to optimize and validate a GC-MS method for the quantitative determination of anabolic steroids in tablet, aqueous suspension and oil solution forms, and to analyze pharmaceutical products sent to Brazilian Federal Police (BFP) for forensic analysis...
April 5, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28431271/investigation-of-pathology-malpractice-claims-in-china-from-2002-2015
#2
Yuan Li, Dong Gao, Meng Tu, Ying-Zhen Luo, Zhen-Hua Deng
OBJECTIVE: To examine pathology-related medical claims in China and identify the most common errors to result in such claims. METHOD: A retrospective analysis was performed of 71 forensic evaluation reports carried out in two Chinese institutes of forensic medicine between 2002 and 2015 due to suspicion of medical malpractice. The judicial outcomes of each case were also reviewed when available. RESULTS: Of 71 cases, 54 cases had judicial outcomes...
April 15, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28425888/-satisfa%C3%A3-%C3%A3-o-com-o-internato-m%C3%A3-dico-em-portugal
#3
Miguel Bigotte Vieira, Pedro Godinho, Nuno Gaibino, Raquel Dias, Agostinho Sousa, Inês Madanelo, Francisco Ribeiro-Mourão, Mariana Brandão, Sónia Duarte, Tiago Meirinhos, Ana Luísa Catarino, Cláudio Espírito Santo, Ricardo Caiado, Ricardo Marques, Ana Gonçalves Ferreira, Carlos Ramalheira, João Valente Jorge, Marta Losada, Mário Santos, Edson Oliveira, João Paulo Farias, José Manuel Silva
INTRODUCTION: In the last years, the global context of medical education and Medical Residency programs in Portugal suffered substantial changes. The primary objective of this study was to evaluate and characterize medical residents ́ satisfaction with medical residency programs in Portugal and to identify features that could be improved. MATERIAL AND METHODS: We utilized as model the survey Postgraduate Hospital Educational Environment Measure that has been developed in the United Kingdom and is speci cally targeted to medical residents...
December 30, 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28419893/carbon-monoxide-related-fatalities-a-60-year-single-institution-experience
#4
Martin Janík, Michaela Ublová, Štepánka Kučerová, Petr Hejna
OBJECTIVE: Though carbon monoxide (CO) poisonings account currently for a relatively small percentage of total non-natural deaths in Europe, they represent a serious public health burden and significant component of avoidable mortality in many countries. Our aim was to investigate long-term trends and to determine epidemiologic characteristics of the CO-related deaths in the Czech Republic, recorded at the Department of Forensic Medicine in Hradec Králové. METHODS: This was an autopsy-based single-centre retrospective cohort study of all fatalities caused by CO poisoning over six decades (1947-2006)...
April 13, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28418938/a-study-on-postmortem-wound-dating-by-gross-and-histopathological-examination-of-abrasions
#5
Javaregowda Vinay, Sathyanarayana Harish, Gouri S R Mangala, Basappa S Hugar
INTRODUCTION: Abrasions are the most common blunt force injuries. The precise dating of injury is extremely important in forensic medicine practice. As we know, the wound healing occurs in well-orchestrated sequence, consisting of inflammation, proliferation, and maturation.A study of occurrence of such phases will help in understanding the sequence of events in wound healing. In this context, this study of wound dating from gross and microscopic level was taken. MATERIALS AND METHODS: Postmortem study of wound dating by gross and histopathological examination of abrasions was carried out in the Department of Forensic Medicine, in M...
April 17, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28405674/-new-developments-in-molecularbiological-diagnostic
#6
Christine Mannhalter
Today, we have access to excellent and advanced molecular methods that are already widely used. This requires rules to control the quality of the methods as well as the laboratory. Both aspects will be discussed in the article. Following the isolation of nucleic acids they are used for genotyping which allows to address several questions: diagnosis of inherited diseases, inherited predispositions, forensic analyses, identification and typing of bacteria or viruses, elucidation of evolutionary aspects. Importantly, it has to be realized that the type and heterogeneity of phenotypically relevant mutations determines the method used for testing...
April 13, 2017: Hämostaseologie
https://www.readbyqxmd.com/read/28403803/metabolic-profile-of-flunitrazepam-clinical-and-forensic-toxicological-aspects
#7
Ricardo Jorge Dinis-Oliveira
BACKGROUND: Flunitrazepam is a potent hypnotic, sedative, and amnestic drug used to treat insomnia and as a pre-anesthetic agent. The illicit practice in drug-facilitated sexual assault has been implicating important clinical and forensic issues. OBJECTIVE: In this work the metabolism of flunitrazepam was fully reviewed. METHODS: Flunitrazepam and related known metabolizing enzymes and metabolites were searched in books and in PubMed (U.S...
April 7, 2017: Drug Metabolism Letters
https://www.readbyqxmd.com/read/28391742/the-use-of-human-samples-obtained-during-medicolegal-autopsies-in-research-an-introduction-to-current-conditions-and-initiatives-in-japan
#8
Takako Tsujimura-Ito, Yusuke Inoue, Kaori Muto, Ken-Ichi Yoshida
Background Leftover samples obtained during autopsies are extremely important basic materials for forensic research. However, there are no established practices for research-related use of obtained samples. Objective This study discusses good practice for the secondary use of samples collected during medicolegal autopsies. Methods A questionnaire was posted to all 76 departments of forensic medicine performing medicolegal autopsies in Japan, and 48 responses were received (response rate: 63.2%). As a secondary analysis, we surveyed information provided on department websites...
January 1, 2017: Medicine, Science, and the Law
https://www.readbyqxmd.com/read/28383611/training-in-occupational-medicine-jurisprudential-malfunctions-in-the-italian-system-and-european-perspectives
#9
L Cegolon, W C Heymann, C Xodo, J H Lange
BACKGROUND: To practice occupational health in Europe, a medical doctor must qualify in occupational medicine. This requires a period of postgraduate specialist medical training lasting a minimum of four years, in conformity with European regulations, to obtain a certificate of completion of training which is then mutually recognized within the entire European Union. DISCUSSION: In 2002 an Italian law allowed doctors specialized in public health medicine and legal/forensic medicine to also practice as consultants in occupational medicine in the country...
May 2017: Annali di Igiene: Medicina Preventiva e di Comunità
https://www.readbyqxmd.com/read/28362021/sexual-dimorphism-in-base-of-skull
#10
Anabel Amores-Ampuero
Sex determination is an important task in forensic medicine and physical anthropology. The aims of this study were to assess the presence of sexual dimorphism in the base of the skull and to compare the accuracy of sex estimation by this method with that achieved in other metric studies of this region. The sample comprised 109 individuals (53 males and 56 females) of known sex, age, and cause of death from San José cemetery in Granada (Spain). Six dimensions were analyzed and discriminant function analysis was performed...
January 26, 2017: Anthropologischer Anzeiger; Bericht über die Biologisch-anthropologische Literatur
https://www.readbyqxmd.com/read/28350333/molecular-imprinting-applications-in-forensic-science
#11
REVIEW
Erkut Yılmaz, Bora Garipcan, Hirak K Patra, Lokman Uzun
Producing molecular imprinting-based materials has received increasing attention due to recognition selectivity, stability, cast effectiveness, and ease of production in various forms for a wide range of applications. The molecular imprinting technique has a variety of applications in the areas of the food industry, environmental monitoring, and medicine for diverse purposes like sample pretreatment, sensing, and separation/purification. A versatile usage, stability and recognition capabilities also make them perfect candidates for use in forensic sciences...
March 28, 2017: Sensors
https://www.readbyqxmd.com/read/28342827/foreign-citizen-mortality-in-iceland-january-2006-december-2016
#12
S N Kunz, R Bingert
BACKGROUND: In recent years, tourism has become the number one account for foreign exchange income in Iceland, overtaking the fisheries industry and aluminium production. The rise of tourism has strongly affected Icelandic society in various sectors. With the increase of tourists visiting Iceland, the number of foreign citizens that died and were autopsied also rose. METHOD: Data were collected from the Department of Forensic Pathology at Landspitali University Hospital in Reykjavik for the period January 2006 - December 2016...
March 23, 2017: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/28326114/minnesota-multiphasic-personality-inventory-characteristics-of-parricide-offenders-with-schizophrenia-in-korea
#13
Sang Yeop Lee, Myung Ho Lim, Jangkyu Lee, Geumsook Shim, Yeon Kim, Jin Ah Do, Soo Jung Lee, Jong Hyuck Choi, Jae Woo Lee
OBJECTIVE: This study aims to examine the personality characteristics in parricide offenders, by using the Minnesota Multiphasic Personality Inventory (MMPI) test, which is commonly used in clinical medicine. METHODS: A total of 73 parricide offenders with schizophrenia who were admitted to National Forensic Hospital in Gongju city between September 2014 and February 2015, and 104 comparison schizophrenia patients who had been admitted to Dankook University Hospital in Cheonan city the same hospital, completed the Korean version of the MMPI...
March 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/28322729/reprint-of-standardisation-and-use-of-the-alcohol-biomarker-carbohydrate-deficient-transferrin-cdt
#14
Anders Helander, Jos Wielders, Raymond Anton, Torsten Arndt, Vincenza Bianchi, Jean Deenmamode, Jan-Olof Jeppsson, John B Whitfield, Cas Weykamp, François Schellenberg
Carbohydrate-deficient transferrin (CDT) is a glycoform profile of serum transferrin that increases in response to sustained high alcohol intake and over the last decades has become an important alcohol biomarker with clinical and forensic applications. However, the wide range of CDT measurement procedures has resulted in lack of uniform results and reference limits, and hampered comparison of results. In 2005, the IFCC therefore founded a special working group (WG) aiming for standardisation of CDT measurement...
March 18, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28298188/enrichment-activities-in-the-medical-school-psychiatry-programme-could-this-be-a-key-to-engaging-medical-students-in-psychiatry-a-study-from-a-high-secure-forensic-psychiatric-uk-hospital
#15
Anna-Marie Mortlock, Ignazio Puzzo, Sophie Taylor, Veena Kumari, Susan Young, Samrat Sengupta, Mrigendra Das
BACKGROUND: The majority of research studies on medical student attitudes toward psychiatry focus on influencing factors and the medical school experience. This study evaluates the effectiveness of a one-day visit to a high secure forensic psychiatric unit on medical students' attitudes towards psychiatry and also assesses career intentions and the factors influencing these. METHOD: Change in attitudes and career intention were measured by administering a questionnaire, which included the 30-item Attitudes Toward Psychiatry (ATP-30) survey, at the start (time 1) and end (time 2) of the one-day visit...
March 16, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28295603/rapid-abo-genotyping-by-high-speed-droplet-allele-specific-pcr-using-crude-samples
#16
Chiaki Taira, Kazuyuki Matsuda, Naoya Takeichi, Satomi Furukawa, Mitsutoshi Sugano, Takeshi Uehara, Nobuo Okumura, Takayuki Honda
BACKGROUND: ABO genotyping has common tools for personal identification of forensic and transplantation field. We developed a new method based on a droplet allele-specific PCR (droplet-AS-PCR) that enabled rapid PCR amplification. We attempted rapid ABO genotyping using crude DNA isolated from dried blood and buccal cells. METHODS: We designed allele-specific primers for three SNPs (at nucleotides 261, 526, and 803) in exons 6 and 7 of the ABO gene. We pretreated dried blood and buccal cells with proteinase K, and obtained crude DNAs without DNA purification...
March 13, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28295575/definition-and-assessment-of-disability-in-mental-disorders-under-the-perspective-of-the-international-classification-of-functioning-disability-and-health-icf
#17
Michael Linden
This article provides an overview of definitions and assessment instruments of disability, an important topic in the diagnosis and treatment of chronic illnesses, and in expert appraisals in social and forensic medicine. Health problems are manifested not only in symptoms, but also regularly in impairment or disability in everyday life, which is especially true for mental disorders. According to the International Classification of Functioning, Disability and Health (ICF) of the World Health Organization, disability can be understood as chronic suffering from symptoms of illness, or limitations of executing capacities, or inability to participate in selected areas of life...
March 14, 2017: Behavioral Sciences & the Law
https://www.readbyqxmd.com/read/28260754/anthropometric-study-of-face-on-bangladeshi-adult-garo-male
#18
A Kabir, M Khalil, S Z Sultana, S Choudhury, S Farjan, Z Ahmed, S Ajmery, E Z Epsi, R S Zisa, M Ismatsara
The present cross sectional descriptive type of study provides a standard for Bangladeshi Garo male regarding physiognomical face height, morphological face height and maximum facial breadth in Mymensingh Sadar, Haluaghat, Madhuopor Upazilas from July 2015 to June 2016. An attempt has been made out to find out correlation of stature with the parameters and to measure different face index. The current study also generates different face types on the basis of morphological face index. The study was done on 121 Garo male between 25-45 years of age in Bangladesh...
January 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28256255/the-evaluation-stage-of-the-hoeven-outcome-monitor-hom-towards-an-evidence-based-groundwork-in-forensic-mental-health
#19
Lobke H Keune, Vivienne de Vogel, Hjalmar J C van Marle
This study examined if a macro-, meso-, and micro outcome measurement instrument that constitutes the evaluation stage of a Dutch forensic psychiatric outcome monitor, the Hoeven Outcome Monitor (HOM), can provide a first step towards a more evidence based groundwork in forensic mental health. General, serious, very serious, special, and tbs meriting recidivism during treatment, after treatment, and overall were charted for forensic psychiatric patients discharged from a Dutch forensic psychiatric centre between 1999 and 2008 (N=164)...
February 27, 2017: International Journal of Law and Psychiatry
https://www.readbyqxmd.com/read/28255632/population-based-autopsy-study-of-traumatic-fatalities
#20
S Saar, A Lomp, J Laos, V Mihnovitš, R Šalkauskas, T Lustenberger, M Väli, U Lepner, P Talving
BACKGROUND: Injuries result in 5.8 million global fatalities annually and are the leading cause of death in younger individuals. Nevertheless, population-based autopsy investigations on traumatic deaths are scarce. We set out to study all consecutive autopsies on traumatic fatalities performed in a 5-year time segment in Estonia. METHODS: After the ethics review board approval, all consecutive autopsies after blunt or penetrating deaths occurring in prehospital or in-hospital settings between January 1, 2009, and December 31, 2013, were retrospectively reviewed using the National Forensic Medicine Database...
March 2, 2017: World Journal of Surgery
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