keyword
MENU ▼
Read by QxMD icon Read
search

Indirect Aggression

keyword
https://www.readbyqxmd.com/read/28073033/situating-violent-ideations-within-the-landscape-of-mental-health-associations-between-violent-ideations-and-dimensions-of-mental-health
#1
Aja Louise Murray, Manuel Eisner, Ingrid Obsuth, Denis Ribeaud
Violent ideations occur more frequently in individuals with mental health problems. They may be of interest in clinical contexts as possible indicators of dangerousness, as corollaries of mental health problems, as candidate treatment targets and as potentially playing a role in perpetuation or onset of symptoms. In spite of their relevance to mental health, some fundamental questions about their place within the broader landscape of mental health problems remain unanswered. To provide a basic characterisation of the relations between violent ideations and dimensions of mental health and provide a foundation for future research in this area we factor analysed a measure of violent ideations and an omnibus measure of mental health dimensions in a normative sample of 1306 youth (at age 17)...
January 3, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28052762/indirect-treatment-comparison-of-dabrafenib-plus-trametinib-versus-vemurafenib-plus-cobimetinib-in-previously-untreated-metastatic-melanoma-patients
#2
Adil Daud, Japinder Gill, Sheily Kamra, Lei Chen, Amit Ahuja
BACKGROUND: Metastatic melanoma is an aggressive form of skin cancer with a high mortality rate and the fastest growing global incidence rate of all malignancies. The introduction of BRAF/MEK inhibitor combinations has yielded significant increases in PFS and OS for melanoma. However, at present, no direct comparisons between different BRAF/MEK combinations have been conducted. In light of this, an indirect treatment comparison was performed between two BRAF/MEK inhibitor combination therapies for metastatic melanoma, dabrafenib plus trametinib and vemurafenib plus cobimetinib, in order to understand the relative efficacy and toxicity profiles of these therapies...
January 4, 2017: Journal of Hematology & Oncology
https://www.readbyqxmd.com/read/28045283/classroom-level-adversity-associations-with-children-s-internalizing-and-externalizing-behaviors-across-elementary-school
#3
Tashia Abry, Crystal I Bryce, Jodi Swanson, Robert H Bradley, Richard A Fabes, Robert F Corwyn
Concerns regarding the social-behavioral maladjustment of U.S. youth have spurred efforts among educators and policymakers to identify and remedy educational contexts that exacerbate children's anxiety, depression, aggression, and misconduct. However, investigations of the influence of collective classroom student characteristics on individuals' social-behavioral functioning are few. The present study examined concurrent and longitudinal relations between adversity factors facing the collective classroom student group and levels of children's internalizing and externalizing behaviors across the elementary school years, and whether the pattern of relations differed for girls and boys...
January 2, 2017: Developmental Psychology
https://www.readbyqxmd.com/read/28031080/the-interaction-between-monoamine-oxidase-a-and-punitive-discipline-in-the-development-of-antisocial-behavior-mediation-by-maladaptive-social-information-processing
#4
Chardée A Galán, Daniel Ewon Choe, Erika E Forbes, Daniel S Shaw
Previous studies demonstrate that boys' monoamine oxidase A (MAOA) genotype interacts with adverse rearing environments in early childhood, including punitive discipline, to predict later antisocial behavior. Yet the mechanisms by which MAOA and punitive parenting interact during childhood to amplify risk for antisocial behavior are not well understood. In the present study, hostile attributional bias and aggressive response generation during middle childhood, salient aspects of maladaptive social information processing, were tested as possible mediators of this relation in a sample of 187 low-income men followed prospectively from infancy into early adulthood...
December 29, 2016: Development and Psychopathology
https://www.readbyqxmd.com/read/28007644/association-between-htr1b-alleles-and-suicidal-ideation-in-individuals-with-major-depressive-disorder
#5
Wei-Tsung Kao, Ming-Chang Yang, For-Wey Lung
Serotonin receptors, also known as 5-hydroxytryptamine receptors (HTRs), play a role in individuals' vulnerability to major depressive disorders (MDDs) and/or suicide attempts. In the first part of the study, we recruited 789 Taiwanese participants, which included 285 MDD patients, 191 MDD patients with a history of suicide attempts (MS), and 313 controls. The three groups were genotyped to identify HTR single nucleotide polymorphisms (SNPs) and we analyzed the correlations among the three groups. In the second part of the study, which involved a functional test of HTR1B allelic and haplotype variants, another 113 MDD patients were recruited...
December 19, 2016: Neuroscience Letters
https://www.readbyqxmd.com/read/27992551/affluence-and-private-health-insurance-influence-treatment-and-survival-in-non-hodgkin-s-lymphoma
#6
Harry Comber, Marianna De Camargo Cancela, Trutz Haase, Howard Johnson, Linda Sharp, Jonathan Pratschke
BACKGROUND: The aim of this study was to investigate inequalities in survival for non-Hodgkin's lymphoma (NHL), distinguishing between direct and indirect effects of patient, social and process-of-care factors. METHODS: All cases of NHL diagnosed in Ireland in 2004-2008 were included. Variables describing patient, cancer, stage and process of care were included in a discrete-time model of survival using Structural Equation Modelling software. RESULTS: Emergency admissions were more common in patients with co-morbid conditions or with more aggressive cancers, and less frequent for patients from more affluent areas...
2016: PloS One
https://www.readbyqxmd.com/read/27992079/expression-of-claudin-11-by-tumor-cells-in-cutaneous-squamous-cell-carcinoma-is-dependent-on-the-activity-of-p38%C3%AE
#7
Liisa Nissinen, Elina Siljamäki, Pilvi Riihilä, Minna Piipponen, Mehdi Farshchian, Atte Kivisaari, Markku Kallajoki, Laura Raiko, Juha Peltonen, Sirkku Peltonen, Veli-Matti Kähäri
The incidence of cutaneous squamous cell carcinoma (cSCC) is rapidly increasing and the prognosis of patients with metastatic disease is poor. There is an emerging need to identify molecular markers for predicting aggressive behavior of cSCC. Here, we have examined the role of tight junction components in the progression of cSCC. The expression pattern of mRNAs for tight junction components was determined with RNA sequencing and oligonucleotide array-based expression analysis from cSCC cell lines (n=8) and normal human epidermal keratinocytes (NHEK, n=5)...
December 19, 2016: Experimental Dermatology
https://www.readbyqxmd.com/read/27902950/harsh-parenting-and-peer-acceptance-in-chinese-early-adolescents-three-child-aggression-subtypes-as-mediators-and-child-gender-as-moderator
#8
Mingzhong Wang
This study examined the mediating roles of three types of child aggression in the relation between harsh parenting and Chinese early adolescents' peer acceptance as well as the moderating role of child gender on this indirect relation. 833 children (mean age=13.58, 352 girls) with their parents were recruited as participants from two junior high schools in Shandong Province, People's Republic of China. The results showed that paternal harsh parenting was only associated with boys' aggressive behaviors and maternal harsh parenting was only associated with boys' and girls' verbal aggression...
January 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/27871720/-guidelines-for-the-prescription-of-mood-stabilizers-for-adolescents-a-literature-review
#9
G Munch, N Godart
INTRODUCTION: Adolescence is a unique phase of the human developmental process. In adolescents, psychotropic medications may have different efficacy and tolerance profiles compared to those at other stages of the lifespan. Mood stabilizers are a complex pharmacological category including lithium, some anticonvulsants, and some second generation antipsychotics. Focusing on this class of pharmacological agents, we aim to answer the following questions: in which indications and according to which modalities should mood stabilizers be prescribed during adolescence? METHODS: Information was sought from the websites of the French Haute Autorité de santé (HAS) and Agence nationale de sécurité du médicament et des produits de santé (ANSM), the American Food and Drug Administration (FDA) and the British National Institute for Health and Clinical Excellence (NICE)...
November 18, 2016: L'Encéphale
https://www.readbyqxmd.com/read/27866948/pulmonary-embolism-rates-following-total-hip-arthroplasty-with-prophylactic-anticoagulation-some-pulmonary-emboli-cannot-be-avoided
#10
Jay R Lieberman, Vincent Cheng, Mark P Cote
BACKGROUND: A symptomatic pulmonary embolism (PE) after total joint arthroplasty has been described as a "never event." Despite potent anticoagulants and improvements in patient care, PE continues to occur following total hip arthroplasty (THA). This study evaluates symptomatic PE rates over time in THA patients enrolled in multicenter randomized clinical trials (RCTs) assessing the efficacy of venous thromboembolism prophylaxis regimens. METHODS: The MEDLINE and Cochrane Central Register of Controlled Trials were searched to identify clinical trials assessing prophylactic anticoagulation in patients undergoing THA between January 1995 and December 2015...
September 28, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/27856663/stable-activation-of-fibroblasts-in-rheumatic-arthritis-causes-and-consequences
#11
REVIEW
Adelheid Korb-Pap, Jessica Bertrand, Joanna Sherwood, Thomas Pap
The progressive destruction of articular cartilage is a hallmark of RA, a systemic autoimmune disease predominantly affecting synovial joints that often results in severe disability. Fibroblast-like synoviocytes (FLSs) have been demonstrated to play a key role in both the initiation and perpetuation of the disease. During RA pathogenesis, FLSs acquire a permanently aggressive, tumour-like phenotype that mediates cartilage destruction both directly and indirectly. This short review summarizes the recent advances in the understanding of FLS cellular transformation during RA, as well as the consequences for disease progression and for novel treatment strategies...
December 2016: Rheumatology
https://www.readbyqxmd.com/read/27843576/micrornas-interfere-with-dna-methylation-in-rheumatoid-arthritis-synovial-fibroblasts
#12
Niharika Gaur, Emmanuel Karouzakis, Selene Glück, Edvardas Bagdonas, Astrid Jüngel, Beat A Michel, Renate E Gay, Steffen Gay, Mojca Frank-Bertoncelj, Michel Neidhart
BACKGROUND: The DNA of rheumatoid arthritis synovial fibroblasts (RASF) is globally hypomethylated; this contributes to an aggressive behaviour. In an attempt to remethylate these cells, we supplemented with methyl donors. We investigated the possible interference of microRNAs (miRs). MATERIAL AND METHODS: RASF were treated with L-methionine or betaine. Transcripts of de novo methyltransferases (DNMTs) and miRs were measured by real-time PCR, and a transcription PCR array was performed...
2016: RMD Open
https://www.readbyqxmd.com/read/27831734/relations-between-traumatic-stress-dimensions-of-impulsivity-and-reactive-and-appetitive-aggression-in-individuals-with-refugee-status
#13
Mareike Augsburger, Katalin Dohrmann, Maggie Schauer, Thomas Elbert
Objective: Traumatic stressors and other forms of adversities, especially when experienced during childhood, shape aggressive behavior. Effects of differential dimensions of impulsivity on the relationship between psychological trauma, reactive aggression (defensive survival response to threat), and appetitive aggression (the pleasure of attacking and fighting) have not yet been assessed. Method: Using structural equation modeling, we sought to uncover precursors of reactive and appetitive aggression investigating a sample of 94 adult individuals with refugee status...
November 10, 2016: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/27831608/-aggressive-and-prosocial-behaviors-among-schoolchildren-living-in-environments-with-high-levels-of-poverty
#14
José William Martínez, José Rafael Tovar Cuevas, Andrés Felipe Ochoa Muñoz
Objetives.: To assess the levels of direct and indirect aggression and prosocial behaviors among schoolchildren at public schools located in 13 municipalities of an intermediate region of Colombia. Materials and Methods.: A total of 2,785 children aged 3-11 years were assessed using an instrument validated for the Colombian population that measures aggression and prosocial behavior via direct observations of schoolteachers. Results.: Boys predominantly exhibited behaviors associated with direct aggression (22...
July 2016: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/27817219/current-complications-and-treatment-of-aspirin-exacerbated-respiratory-disease
#15
Kevin A Cook, Donald D Stevenson
Aspirin-exacerbated respiratory disease is defined by the clinical tetrad of aspirin sensitivity, nasal polyps, asthma, and chronic rhinosinusitis. Patients experience acute upper and lower airway reactions with exposure to aspirin and other cyclooxygenase-1 inhibiting medications. However, airway inflammation and disease progression occur even in the absence of exposure to these medications, often leading to aggressive polyp formation and need for systemic corticosteroids to treat exacerbations in asthma and rhinosinusitis...
November 17, 2016: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/27812416/baseline-reef-health-surveys-at-bangka-island-north-sulawesi-indonesia-reveal-new-threats
#16
Massimo Ponti, Francesca Fratangeli, Nicolò Dondi, Marco Segre Reinach, Clara Serra, Michael J Sweet
Worldwide coral reef decline appears to be accompanied by an increase in the spread of hard coral diseases. However, whether this is the result of increased direct and indirect human disturbances and/or an increase in natural stresses remains poorly understood. The provision of baseline surveys for monitoring coral health status lays the foundations to assess the effects of any such anthropogenic and/or natural effects on reefs. Therefore, the objectives of this present study were to provide a coral health baseline in a poorly studied area, and to investigate possible correlations between coral health and the level of anthropogenic and natural disturbances...
2016: PeerJ
https://www.readbyqxmd.com/read/27810636/interactions-with-community-members-and-institutions-preventive-pathways-for-child-maltreatment
#17
Yiwen Cao, Kathryn Maguire-Jack
Parents interact with their environment in important ways that may impact their ability to parent their children positively. The current study uses data from the age 3 wave of the Fragile Families and Child Wellbeing study to investigate whether neighborhood processes and community participation relate to internal control, and whether these three variables are associated with child maltreatment behaviors. Using structural equation modeling, the direct and indirect effects of the environment (neighborhood disorder, social control, and social cohesion) and community participation on child maltreatment are tested...
December 2016: Child Abuse & Neglect
https://www.readbyqxmd.com/read/27795443/jund-ap-1-antagonizes-the-induction-of-dapk1-to-promote-the-survival-of-v-src-transformed-cells
#18
Bart M Maślikowski, Lizhen Wang, Ying Wu, Ben Fielding, Pierre-André Bédard
: The increase in AP-1 activity is a hallmark of cell transformation by tyrosine kinases. Previously, we reported that blocking AP-1 using the c-Jun dominant negative mutant TAM67 induced senescence, adipogenesis, or apoptosis in v-Src-transformed chicken embryo fibroblasts (CEFs) whereas inhibition of JunD by short hairpin RNA (shRNA) specifically induced apoptosis. To investigate the role of AP-1 in Src-mediated transformation, we undertook a gene profiling study to characterize the transcriptomes of v-Src-transformed CEFs expressing either TAM67 or the JunD shRNA...
January 1, 2017: Journal of Virology
https://www.readbyqxmd.com/read/27787569/-cardiopulmonary-resuscitation-in-cardiac-arrest-following-trauma
#19
B A Leidel, K-G Kanz
For decades, survival rates of cardiac arrest following trauma were reported between 0 and 2 %. Since 2005, survival rates have increased with a wide range up to 39 % and good neurological recovery in every second person injured for unknown reasons. Especially in children, high survival rates with good neurologic outcomes are published. Resuscitation following traumatic cardiac arrest differs significantly from nontraumatic causes. Paramount is treatment of reversible causes, which include massive bleeding, hypoxia, tension pneumothorax, and pericardial tamponade...
October 27, 2016: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://www.readbyqxmd.com/read/27771387/hdv-rna-replication-is-associated-with-hbv-repression-and-interferon-stimulated-genes-induction-in-super-infected-hepatocytes
#20
Dulce Alfaiate, Julie Lucifora, Natali Abeywickrama-Samarakoon, Maud Michelet, Barbara Testoni, Jean-Claude Cortay, Camille Sureau, Fabien Zoulim, Paul Dény, David Durantel
Hepatitis D virus (HDV) super-infection of Hepatitis B virus (HBV)-infected patients is the most aggressive form of viral hepatitis. HDV infection is not susceptible to direct anti-HBV drugs, and only suboptimal antiviral responses are obtained with interferon (IFN)-alpha-based therapy. To get insights on HDV replication and interplay with HBV in physiologically relevant hepatocytes, differentiated HepaRG (dHepaRG) cells, previously infected or not with HBV, were infected with HDV, and viral markers were extensively analyzed...
October 19, 2016: Antiviral Research
keyword
keyword
57458
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"