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https://www.readbyqxmd.com/read/28446682/smartphone-controlled-optogenetically-engineered-cells-enable-semiautomatic-glucose-homeostasis-in-diabetic-mice
#1
REVIEW
Jiawei Shao, Shuai Xue, Guiling Yu, Yuanhuan Yu, Xueping Yang, Yu Bai, Sucheng Zhu, Linfeng Yang, Jianli Yin, Yidan Wang, Shuyong Liao, Sanwei Guo, Mingqi Xie, Martin Fussenegger, Haifeng Ye
With the increasingly dominant role of smartphones in our lives, mobile health care systems integrating advanced point-of-care technologies to manage chronic diseases are gaining attention. Using a multidisciplinary design principle coupling electrical engineering, software development, and synthetic biology, we have engineered a technological infrastructure enabling the smartphone-assisted semiautomatic treatment of diabetes in mice. A custom-designed home server SmartController was programmed to process wireless signals, enabling a smartphone to regulate hormone production by optically engineered cells implanted in diabetic mice via a far-red light (FRL)-responsive optogenetic interface...
April 26, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/28442456/the-malaria-system-microapp-a-new-mobile-device-based-tool-for-malaria-diagnosis
#2
Allisson Dantas Oliveira, Clara Prats, Mateu Espasa, Francesc Zarzuela Serrat, Cristina Montañola Sales, Aroa Silgado, Daniel Lopez Codina, Mercia Eliane Arruda, Jordi Gomez I Prat, Jones Albuquerque
BACKGROUND: Malaria is a public health problem that affects remote areas worldwide. Climate change has contributed to the problem by allowing for the survival of Anopheles in previously uninhabited areas. As such, several groups have made developing news systems for the automated diagnosis of malaria a priority. OBJECTIVE: The objective of this study was to develop a new, automated, mobile device-based diagnostic system for malaria. The system uses Giemsa-stained peripheral blood samples combined with light microscopy to identify the Plasmodium falciparum species in the ring stage of development...
April 25, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28438939/emergence-and-evolution-of-multidrug-resistant-klebsiella-pneumoniae-with-both-blakpc-and-blactx-m-integrated-in-chromosome
#3
Weihua Huang, Guiqing Wang, Robert Sebra, Jian Zhuge, Changhong Yin, Maria E Aguero-Rosenfeld, Audrey N Schuetz, Nevenka Dimitrova, John T Fallon
The extended-spectrum β-lactamase (ESBL)- and Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae represent serious and urgent threats to public health. In a retrospective study of multidrug-resistant K. pneumoniae, we identified three clinical isolates, CN1, CR14 and NY9, carrying both blaCTX-M and blaKPC genes. The complete genomes of these three K. pneumoniae isolates were de novo assembled by using both short- and long-read whole-genome sequencing. In CR14 and NY9, blaCTX-M and blaKPC were carried on two different plasmids...
April 24, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28438218/malaria-elimination-in-lao-pdr-the-challenges-associated-with-population-mobility
#4
REVIEW
Sengchanh Kounnavong, Deyer Gopinath, Bouasy Hongvanthong, Chanthalone Khamkong, Odai Sichanthongthip
Although the Lao People's Democratic Republic (Lao PDR) is comparatively small landlocked country with patterns of both in- and out-migration, its human migration situation has been poorly studied. This is despite all of the country's 18 provinces sharing both official and unofficial border checkpoints with neighboring countries. Economic reforms in the last decade have seen a gradual increase in the promotion of foreign investment, and main towns and transportation networks have been expanding thus offering new opportunities for livelihoods and economic activities...
April 25, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28435321/a-behavioral-medicine-intervention-for-community-dwelling-older-adults-with-chronic-musculoskeletal-pain-protocol-for-a-randomized-controlled-trial
#5
Sara Cederbom, Eva Denison, Astrid Bergland
BACKGROUND: Chronic musculoskeletal pain is a major health problem among older adults, particularly those who live alone and/or those who are dependent on formal care. Chronic pain is associated with mobility problems, falls, fear of falling, catastrophizing thoughts, and a lower quality of life. Research shows that physical therapy interventions based on behavioral medicine approaches are beneficial for middle-aged adults with chronic pain. However, there appears to be no previous randomized controlled trials (RCTs) based on this theoretical framework that have examined the effect on older adults with chronic musculoskeletal pain who live alone at home and are dependent on formal care to manage their everyday lives...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28428734/defining-a-staged-based-process-for-economic-and-financial-evaluations-of-mhealth-programs
#6
Amnesty E LeFevre, Samuel D Shillcutt, Sean Broomhead, Alain B Labrique, Tom Jones
Mobile and wireless technology for health (mHealth) has the potential to improve health outcomes by addressing critical health systems constraints that impede coverage, utilization, and effectiveness of health services. To date, few mHealth programs have been implemented at scale and there remains a paucity of evidence on their effectiveness and value for money. This paper aims to improve understanding among mHealth program managers and key stakeholders of how to select methods for economic evaluation (comparative analysis for determining value for money) and financial evaluation (determination of the cost of implementing an intervention, estimation of costs for sustaining or expanding an intervention, and assessment of its affordability)...
2017: Cost Effectiveness and Resource Allocation: C/E
https://www.readbyqxmd.com/read/28428158/mobile-application-to-promote-adherence-to-oral-chemotherapy-and-symptom-management-a-protocol-for-design-and-development
#7
Joel Nathan Fishbein, Lauren Ellen Nisotel, James John MacDonald, Nicole Amoyal Pensak, Jamie Michele Jacobs, Clare Flanagan, Kamal Jethwani, Joseph Andrew Greer
BACKGROUND: Oral chemotherapy is increasingly used in place of traditional intravenous chemotherapy to treat patients with cancer. While oral chemotherapy includes benefits such as ease of administration, convenience, and minimization of invasive infusions, patients receive less oversight, support, and symptom monitoring from clinicians. Additionally, adherence is a well-documented challenge for patients with cancer prescribed oral chemotherapy regimens. With the ever-growing presence of smartphones and potential for efficacious behavioral intervention technology, we created a mobile health intervention for medication and symptom management...
April 20, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28428155/using-persuasive-technology-to-increase-physical-activity-in-people-with-chronic-obstructive-pulmonary-disease-by-encouraging-regular-walking-a-mixed-methods-study-exploring-opinions-and-preferences
#8
Yvonne Kiera Bartlett, Thomas L Webb, Mark S Hawley
BACKGROUND: People with chronic obstructive pulmonary disease (PwCOPD) often experience breathlessness and fatigue, making physical activity challenging. Although many persuasive technologies (such as mobile phone apps) have been designed to support physical activity among members of the general population, current technologies aimed at PwCOPD are underdeveloped and only use a limited range of persuasive technology design principles. OBJECTIVE: The aim of this study was to explore how acceptable different persuasive technology design principles were considered to be in supporting and encouraging physical activity among PwCOPD...
April 20, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28423815/mobile-medical-apps-and-mhealth-devices-a-framework-to-build-medical-apps-and-mhealth-devices-in-an-ethical-manner-to-promote-safer-use-a-literature-review
#9
Mary Sharp, Declan O'Sullivan
This paper presents a preliminary literature review in the area of ethics in the development of Mobile Medical Apps and mHealth. The review included both direct health apps and also apps marketed under the area of well-being in addition to mHealth devices. The following words and combinations of them were used to carry out the search for publications, mHealth, Apps, Ethics. The search engines used were Google Scholar, and PubMed. The paper is restricted to publications since 2012. The total number of papers found was 1,920 of which 84 were reviewed...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28423744/design-and-validation-of-a-platform-to-evaluate-mhealth-apps
#10
Daniel Philpott, Aziz Guergachi, Karim Keshavjee
Emerging technologies show great potential in the field of patient care. One such technology is mobile heath applications (mhealth apps), which have exploded in number and variety in recent years, and offer great promise in the ability to collect and monitor patient health data. Despite their apparent success in proliferation and user adoption, these applications struggle to integrate into the primary care system and there is scant information regarding their efficacy to effect patient behavior and consequently health outcomes...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28421308/an-intelligent-remote-monitoring-system-for-total-knee-arthroplasty-patients
#11
Yunus Msayib, Patrick Gaydecki, Michael Callaghan, Nicola Dale, Sheheera Ismail
For the first six weeks following total knee arthroplasty (TKA), a patient will attend an outpatient clinic typically seen twice weekly. Here, an exercise regime is performed and improvement assessed using a hand held goniometer that measures the maximum angle of knee flexion, an important metric of progress. Additionally a series of daily exercises is performed at home, recorded in a diary. This protocol has problems. Patients must attend the hospital with assistance since they are not permitted to drive for six weeks following the procedure; appointments are sometimes missed; there are occasionally not enough physiotherapy appointment available; furthermore, it is difficult to be sure that patients are compliant with their exercises at home...
June 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28420401/using-media-to-impact-health-policy-making-an-integrative-systematic-review
#12
REVIEW
Lama Bou-Karroum, Fadi El-Jardali, Nour Hemadi, Yasmine Faraj, Utkarsh Ojha, Maher Shahrour, Andrea Darzi, Maha Ali, Carine Doumit, Etienne V Langlois, Jad Melki, Gladys Honein AbouHaidar, Elie A Akl
INTRODUCTION: Media interventions can potentially play a major role in influencing health policies. This integrative systematic review aimed to assess the effects of planned media interventions-including social media-on the health policy-making process. METHODS: Eligible study designs included randomized and non-randomized designs, economic studies, process evaluation studies, stakeholder analyses, qualitative methods, and case studies. We electronically searched Medline, EMBASE, Communication and Mass Media Complete, Cochrane Central Register of Controlled Trials, and the WHO Global Health Library...
April 18, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28419529/critical-discourse-analysis-of-social-justice-in-nursing-s-foundational-documents
#13
Claire P Valderama-Wallace
OBJECTIVE: Social inequities threaten the health of the global population. A superficial acknowledgement of social justice by nursing's foundational documents may limit the degree to which nurses view injustice as relevant to nursing practice and education. The purpose was to examine conceptualizations of social justice and connections to broader contexts in the most recent editions. DESIGN: Critical discourse analysis examines and uncovers dynamics related to power, language, and inequality within the American Nurses Association's Code of Ethics, Scope and Standards of Practice, and Social Policy Statement...
April 17, 2017: Public Health Nursing
https://www.readbyqxmd.com/read/28413725/trypanosoma-cruzi-reservoir-triatomine-vector-co-occurrence-networks-reveal-meta-community-effects-by-synanthropic-mammals-on-geographic-dispersal
#14
Carlos N Ibarra-Cerdeña, Leopoldo Valiente-Banuet, Víctor Sánchez-Cordero, Christopher R Stephens, Janine M Ramsey
Contemporary patterns of land use and global climate change are modifying regional pools of parasite host species. The impact of host community changes on human disease risk, however, is difficult to assess due to a lack of information about zoonotic parasite host assemblages. We have used a recently developed method to infer parasite-host interactions for Chagas Disease (CD) from vector-host co-occurrence networks. Vector-host networks were constructed to analyze topological characteristics of the network and ecological traits of species' nodes, which could provide information regarding parasite regional dispersal in Mexico...
2017: PeerJ
https://www.readbyqxmd.com/read/28410174/pilot-and-feasibility-test-of-a-mobile-health-supported-behavioral-counseling-intervention-for-weight-management-among-breast-cancer-survivors
#15
Lisa M Quintiliani, Devin M Mann, Marissa Puputti, Emily Quinn, Deborah J Bowen
BACKGROUND: Health behavior and weight management interventions for cancer survivors have the potential to prevent future cancer recurrence and improve long-term health; however, their translation can be limited if the intervention is complex and involves high participant burden. Mobile health (mHealth) offers a delivery modality to integrate interventions into daily life routines. OBJECTIVE: The objective of this study was to evaluate the effects of a one-group trial with a pre-post evaluation design on engagement (use and acceptability), physiological (weight), behavioral (diet and physical activity), and other secondary outcomes...
May 9, 2016: JMIR Cancer
https://www.readbyqxmd.com/read/28409149/collaborative-implementation-strategy-for-newborn-resuscitation-and-essential-care-training-in-the-dominican-republic
#16
REVIEW
Alexandra Leader, Claudia Cadet, Davina Lazala, Wanny Roa, Olga Arroyo, Lloyd Jensen
BACKGROUND: Neonatal mortality accounts for 45% of under-5 mortality worldwide, with 98% of newborn deaths occurring in developing countries. The Dominican Republic (DR) demonstrates one of the highest neonatal mortality rates in Latin America despite broad access to care. Strategies to support professional capacity building and strengthen the local health care system are needed to improve neonatal outcomes in the DR. RATIONALE: Helping babies breathe (HBB) and essential care for every baby (ECEB) are evidence-based newborn resuscitation and essential care training programs that have been shown to improve providers' confidence, knowledge, and clinical skills...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28408361/design-of-a-mobile-app-for-nutrition-education-trec-lifestyle-and-formative-evaluation-with-families-of-overweight-children
#17
Silvia Gabrielli, Marco Dianti, Rosa Maimone, Marta Betta, Lorena Filippi, Monica Ghezzi, Stefano Forti
BACKGROUND: Nutrition and diet apps represent today a popular area of mobile health (mHealth), offering the possibility of delivering behavior change (BC) interventions for healthy eating and weight management in a scalable and cost-effective way. However, if commercial apps for pediatric weight management fail to retain users because of a lack of theoretical background and evidence-based content, mHealth apps that are more evidence-based are found less engaging and popular among consumers...
April 13, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28404468/assessing-the-impact-of-a-program-for-late-surgical-intervention-in-early-blind-children
#18
A Kalia, T Gandhi, G Chatterjee, P Swami, H Dhillon, S Bi, N Chauhan, S D Gupta, P Sharma, S Sood, S Ganesh, U Mathur, P Sinha
OBJECTIVE: Many blind children in the developing world are unable to obtain timely treatment due to lack of financial and medical resources. Can public health programs that identify and treat such children several years after the onset of blindness enhance their quality of life? The notion that visual development is subject to an early 'critical period' argues against this possibility. However, there are inadequate empirical data from humans on this issue. To address this need, we examined the quality of life of children living in India and who were treated for early-onset blindness (before one year of age), due to cataracts or corneal opacities...
May 2017: Public Health
https://www.readbyqxmd.com/read/28403865/implementing-360%C3%A2-quantified-self-for-childhood-obesity-feasibility-study-and-experiences-from-a-weight-loss-camp-in-qatar
#19
Luis Fernandez-Luque, Meghna Singh, Ferda Ofli, Yelena A Mejova, Ingmar Weber, Michael Aupetit, Sahar Karim Jreige, Ahmed Elmagarmid, Jaideep Srivastava, Mohamed Ahmedna
BACKGROUND: The explosion of consumer electronics and social media are facilitating the rise of the Quantified Self (QS) movement where millions of users are tracking various aspects of their daily life using social media, mobile technology, and wearable devices. Data from mobile phones, wearables and social media can facilitate a better understanding of the health behaviors of individuals. At the same time, there is an unprecedented increase in childhood obesity rates worldwide. This is a cause for grave concern due to its potential long-term health consequences (e...
April 13, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28400355/mobile-phone-delivered-cognitive-behavioral-therapy-for-insomnia-a-randomized-waitlist-controlled-trial
#20
Corine Hg Horsch, Jaap Lancee, Fiemke Griffioen-Both, Sandor Spruit, Siska Fitrianie, Mark A Neerincx, Robbert Jan Beun, Willem-Paul Brinkman
BACKGROUND: This study is one of the first randomized controlled trials investigating cognitive behavioral therapy for insomnia (CBT-I) delivered by a fully automated mobile phone app. Such an app can potentially increase the accessibility of insomnia treatment for the 10% of people who have insomnia. OBJECTIVE: The objective of our study was to investigate the efficacy of CBT-I delivered via the Sleepcare mobile phone app, compared with a waitlist control group, in a randomized controlled trial...
April 11, 2017: Journal of Medical Internet Research
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