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https://www.readbyqxmd.com/read/27910749/role-of-toll-like-receptors-in-hepatitis-c-virus-pathogenesis-and-treatment
#1
Usman Ali Ashfaq, Muhammad Sarfaraz Iqbal, Saba Khaliq
Viral infections are rising every day, and viruses appear to be the most dangerous pathogens in the world. Hepatitis C virus (HCV) is accepted as one of the major destructive factors of promoting severe hepatic disorders by infecting more than 180 million individuals throughout the world. Chronic infection caused by HCV poses a serious global health emergency and appears to be a powerful threat to humanity. Almost 20 years have passed since the disclosure of HCV, but even now, treatment preferences remain limited...
2016: Critical Reviews in Eukaryotic Gene Expression
https://www.readbyqxmd.com/read/27908844/quittr-the-design-of-a-video-game-to-support-smoking-cessation
#2
Ivan Bindoff, Kristy de Salas, Gregory Peterson, Tristan Ling, Ian Lewis, Lindsay Wells, Peter Gee, Stuart G Ferguson
BACKGROUND: Smoking is recognized as the largest, single, preventable cause of death and disease in the developed world. While the majority of smokers report wanting to quit, and many try each year, smokers find it difficult to maintain long-term abstinence. Behavioral support, such as education, advice, goal-setting, and encouragement, is known to be beneficial in improving the likelihood of succeeding in a quit attempt, but it remains difficult to effectively deliver this behavioral support and keep the patient engaged with the process for a sufficient duration...
December 1, 2016: JMIR Serious Games
https://www.readbyqxmd.com/read/27900653/a-survey-of-authentication-schemes-in-telecare-medicine-information-systems
#3
Muhammad Umair Aslam, Abdelouahid Derhab, Kashif Saleem, Haider Abbas, Mehmet Orgun, Waseem Iqbal, Baber Aslam
E-Healthcare is an emerging field that provides mobility to its users. The protected health information of the users are stored at a remote server (Telecare Medical Information System) and can be accessed by the users at anytime. Many authentication protocols have been proposed to ensure the secure authenticated access to the Telecare Medical Information System. These protocols are designed to provide certain properties such as: anonymity, untraceability, unlinkability, privacy, confidentiality, availability and integrity...
January 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/27894307/regional-health-workforce-monitoring-as-governance-innovation-a-german-model-to-coordinate-sectoral-demand-skill-mix-and-mobility
#4
E Kuhlmann, O Lauxen, C Larsen
BACKGROUND: As health workforce policy is gaining momentum, data sources and monitoring systems have significantly improved in the European Union and internationally. Yet data remain poorly connected to policy-making and implementation and often do not adequately support integrated approaches. This brings the importance of governance and the need for innovation into play. CASE: The present case study introduces a regional health workforce monitor in the German Federal State of Rhineland-Palatinate and seeks to explore the capacity of monitoring to innovate health workforce governance...
November 28, 2016: Human Resources for Health
https://www.readbyqxmd.com/read/27892525/sxt-r391-integrative-and-conjugative-elements-in-proteus-species-reveal-abundant-genetic-diversity-and-multidrug-resistance
#5
Xinyue Li, Yu Du, Pengcheng Du, Hang Dai, Yujie Fang, Zhenpeng Li, Na Lv, Baoli Zhu, Biao Kan, Duochun Wang
SXT/R391 integrative and conjugative elements (ICEs) are self-transmissible mobile genetic elements that are found in most members of Enterobacteriaceae. Here, we determined fifteen SXT/R391 ICEs carried by Proteus isolates from food (4.2%) and diarrhoea patients (17.3%). BLASTn searches against GenBank showed that the fifteen SXT/R391 ICEs were closely related to that from different Enterobacteriaceae species, including Proteus mirabilis. Using core gene phylogenetic analysis, the fifteen SXT/R391 ICEs were grouped into six distinct clusters, including a dominant cluster and three clusters that have not been previously reported in Proteus isolates...
November 28, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27891356/attitudes-and-perceptions-of-medical-undergraduates-towards-mobile-learning-m-learning
#6
Rakesh Narayan Patil, Balaji D Almale, Mrunal Patil, Amit Gujrathi, Supriya Dhakne-Palwe, Anuradha R Patil, Shriram Gosavi
INTRODUCTION: Mobile technology is one of the latest extensions of technological innovations that can be integrated into medical education. With the aid of these devices, students learn faster outside the classroom by having quick access to the internet and easy retrieval of required health related learning resources to keep alongside of recent trend and development. In medicine practice one has to continuously update his/her medical knowledge and mobile learning will serve as a tool for self-directed learning...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27887610/integral-strategy-to-supportive-care-in-breast-cancer-survivors-through-occupational-therapy-and-a-m-health-system-design-of-a-randomized-clinical-trial
#7
Mario Lozano-Lozano, Lydia Martín-Martín, Noelia Galiano-Castillo, Francisco Álvarez-Salvago, Irene Cantarero-Villanueva, Carolina Fernández-Lao, Carmen Sánchez-Salado, Manuel Arroyo-Morales
BACKGROUND: Technological support using e-health mobile applications (m-health) is a promising strategy to improve the adherence to healthy lifestyles in breast cancer survivors (excess in energy intake or low physical activity are determinants of the risk of recurrence, second cancers and cancer mortality). Moreover, cancer rehabilitation programs supervised by health professionals are needed due to the inherent characteristics of these breast cancer patients. Our main objective is to compare the clinical efficacy of a m-health lifestyle intervention system alone versus an integral strategy to improve Quality of Life in breast cancer survivors...
November 25, 2016: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/27884440/re-infection-with-fasciola-gigantica-6-month-post-treatment-with-triclabendazole-in-cattle-from-mobile-pastoralist-husbandry-systems-at-lake-chad
#8
Helena Greter, Annour A Batil, Idriss O Alfaroukh, Felix Grimm, Bongo N Ngandolo, Jennifer Keiser, Jürg Utzinger, Jakob Zinsstag, Jan Hattendorf
At Lake Chad in central Africa, livestock fascioliasis caused by Fasciola gigantica represents a major veterinary health problem, particularly in cattle reared in mobile pastoralist husbandry systems. We assessed re-infection after a single dose of triclabendazole with fascioliasis in cattle in a mobile pastoralist setting towards the end of the dry season. Within the cattle herds of 14 groups of mobile pastoralists, 375 cattle were randomly selected. A faecal sample was obtained from each animal to determine the prevalence of F...
October 30, 2016: Veterinary Parasitology
https://www.readbyqxmd.com/read/27852423/collaboration-between-non-governmental-organizations-and-public-services-in-health-a-qualitative-case-study-from-rural-ecuador
#9
Olivia Biermann, Martin Eckhardt, Siw Carlfjord, Magnus Falk, Birger C Forsberg
BACKGROUND: Non-governmental organizations (NGOs) have a key role in improving health in low- and middle-income countries. Their work needs to be synergistic, complementary to public services, and rooted in community mobilization and collective action. The study explores how an NGO and its health services are perceived by the population that it serves, and how it can contribute to reducing barriers to care. DESIGN: A qualitative exploratory study was conducted in remote Ecuador, characterized by its widespread poverty and lack of official governance...
2016: Global Health Action
https://www.readbyqxmd.com/read/27833678/telehealth-enabled-emergency-medical-services-program-reduces-ambulance-transport-to-urban-emergency-departments
#10
James R Langabeer, Michael Gonzalez, Diaa Alqusairi, Tiffany Champagne-Langabeer, Adria Jackson, Jennifer Mikhail, David Persse
INTRODUCTION: Emergency medical services (EMS) agencies transport a significant majority of patients with low acuity and non-emergent conditions to local emergency departments (ED), affecting the entire emergency care system's capacity and performance. Opportunities exist for alternative models that integrate technology, telehealth, and more appropriately aligned patient navigation. While a limited number of programs have evolved recently, no empirical evidence exists for their efficacy...
November 2016: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27830250/all-that-glitters-is-not-gold-consumer-health-informatics-and-education-in-the-era-of-social-media-and-health-apps-findings-from-the-yearbook-2016-section-on-consumer-health-informatics
#11
L Fernandez-Luque, P Staccini
OBJECTIVE: To summarize the state of the art published during the year 2015 in the areas related to consumer health informatics and education with a special emphasis on unintended consequences of applying mobile and social media technologies in that domain. METHODS: We conducted a systematic review of articles published in PubMed with a predefined set of queries, which lead to the selection of over 700 potential relevant articles. Section editors screened those papers on the title, abstract, and finally complete paper basis, taking into account the papers' relevance for the section topic...
November 10, 2016: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/27827529/a-design-thinking-approach-to-primary-ovarian-insufficiency
#12
Lisa A Martin, Alison G Porter, Vincent A Pelligrini, Peter A Schnatz, Xuezhi Jiang, Nicole Kleinstreuer, Janet E Hall, Sarah Verbiest, Jill Olmstead, Ryan Fair, Alberto Falorni, Luca Persani, Aleksandar Rajkovic, Khanjan Mehta, Lawrence M Nelson
Most clinicians are not prepared to provide integrated personal care to address all the clinical needs of women with primary ovarian insufficiency. Design thinking is an engineering methodology used to develop and evaluate novel concepts for systems operation. Here we articulate the need for a seamlessly integrated mobile health system to support genomic research as well as patient care. We also review the pathophysiology and management of primary ovarian insufficiency. Molecular understanding regarding the pathogenesis is essential to developing strategies for prevention, earlier diagnosis, and appropriate management of the disorder...
November 9, 2016: Panminerva Medica
https://www.readbyqxmd.com/read/27820878/integrated-versus-non-integrated-orbital-implants-for-treating-anophthalmic-sockets
#13
REVIEW
Silvana Schellini, Regina El Dib, Leandro Re Silva, Joyce G Farat, Yuqing Zhang, Eliane C Jorge
BACKGROUND: Anophthalmia is the absence of one or both eyes, and it can be congenital (i.e. a birth defect) or acquired later in life. There are two main types of orbital implant: integrated, whereby the implant receives a blood supply from the body that allows for the integration of the prosthesis within the tissue; and non-integrated, where the implant remains separate. Despite the remarkable progress in anophthalmic socket reconstruction and in the development of various types of implants, there are still uncertainties about the real roles of integrated (hydroxyapatite (HA), porous polyethylene (PP), composites) and non-integrated (polymethylmethacrylate (PMMA)/acrylic and silicone) orbital implants in anophthalmic socket treatment...
November 7, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27815232/enhancing-self-efficacy-for-help-seeking-among-transition-aged-youth-in-postsecondary-settings-with-mental-health-and-or-substance-use-concerns-using-crowd-sourced-online-and-mobile-technologies-the-thought-spot-protocol
#14
David Wiljer, Alexxa Abi-Jaoude, Andrew Johnson, Genevieve Ferguson, Marcos Sanches, Andrea Levinson, Janine Robb, Olivia Heffernan, Tyson Herzog, Gloria Chaim, Kristin Cleverley, Gunther Eysenbach, Joanna Henderson, Jeffrey S Hoch, Elisa Hollenberg, Huan Jiang, Wanrudee Isaranuwatchai, Marcus Law, Sarah Sharpe, Tim Tripp, Aristotle Voineskos
BACKGROUND: Seventy percent of lifetime cases of mental illness emerge prior to age 24. While early detection and intervention can address approximately 70% of child and youth cases of mental health concerns, the majority of youth with mental health concerns do not receive the services they need. OBJECTIVE: The objective of this paper is to describe the protocol for optimizing and evaluating Thought Spot, a Web- and mobile-based platform cocreated with end users that is designed to improve the ability of students to access mental health and substance use services...
November 4, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27814893/social-determinants-and-lifestyles-integrating-environmental-and-public-health-perspectives
#15
REVIEW
H Graham, P C L White
OBJECTIVE: Industrialization and urbanization have been associated with an epidemiological transition, from communicable to non-communicable disease, and a geological transition that is moving the planet beyond the stable Holocene epoch in which human societies have prospered. The lifestyles of high-income countries are major drivers of these twin processes. Our objective is to highlight the common causes of chronic disease and environmental change and, thereby, contribute to shared perspectives across public health and the environment...
November 1, 2016: Public Health
https://www.readbyqxmd.com/read/27814455/mobile-devices-for-the-remote-acquisition-of-physiological-and-behavioral-biomarkers-in-psychiatric-clinical-research
#16
Zachary W Adams, Erin A McClure, Kevin M Gray, Carla Kmett Danielson, Frank A Treiber, Kenneth J Ruggiero
Psychiatric disorders are linked to a variety of biological, psychological, and contextual causes and consequences. Laboratory studies have elucidated the importance of several key physiological and behavioral biomarkers in the study of psychiatric disorders, but much less is known about the role of these biomarkers in naturalistic settings. These gaps are largely driven by methodological barriers to assessing biomarker data rapidly, reliably, and frequently outside the clinic or laboratory. Mobile health (mHealth) tools offer new opportunities to study relevant biomarkers in concert with other types of data (e...
October 22, 2016: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/27812798/choosing-between-responsive-design-websites-versus-mobile-apps-for-your-mobile-behavioral-intervention-presenting-four-case-studies
#17
Gabrielle M Turner-McGrievy, Sarah B Hales, Danielle E Schoffman, Homay Valafar, Keith Brazendale, R Glenn Weaver, Michael W Beets, Michael D Wirth, Nitin Shivappa, Trisha Mandes, James R Hébert, Sara Wilcox, Andrew Hester, Matthew J McGrievy
Both mobile apps and responsive-design websites (web apps) can be used to deliver mobile health (mHealth) interventions, but it can be difficult to discern which to use in research. The goal of this paper is to present four case studies from behavioral interventions that developed either a mobile app or a web app for research and present an information table to help researchers determine which mobile option would work best for them. Four behavioral intervention case studies (two developed a mobile app, and two developed a web app) presented include time, cost, and expertise...
November 3, 2016: Translational Behavioral Medicine
https://www.readbyqxmd.com/read/27811164/engaging-adolescents-through-participatory-and-qualitative-research-methods-to-develop-a-digital-communication-intervention-to-reduce-adolescent-obesity
#18
William C Livingood, David Monticalvo, Jay M Bernhardt, Kelli T Wells, Todd Harris, Kadra Kee, Johnathan Hayes, Donald George, Lynn D Woodhouse
Background The complexity of the childhood obesity epidemic requires the application of community-based participatory research (CBPR) in a manner that can transcend multiple communities of stakeholders, including youth, the broader community, and the community of health care providers. Aim To (a) describe participatory processes for engaging youth within context of CBPR and broader community, (b) share youth-engaged research findings related to the use of digital communication and implications for adolescent obesity intervention research, and (c) describe and discuss lessons learned from participatory approaches...
November 2, 2016: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/27808084/-use-of-the-smartphone-to-promote-healthy-habits-among-teen-agers-spain
#19
Carme Carrion, Liliana Arroyo Moliner, Conxa Castell, Elisa Puigdomènech, Santiago Felipe Gómez, Laia Domingo, Mireia Espallargues
OBJECTIVE: The PEGASO Project aims to design a technological system aimed at European adolescents to promote healthy lifestyles. The objective was to explore teenagers and their parents and teachers perceptions with regards to mobile technology use in promoting a healthier lifestyle, in terms of food and physical activity. METHODS: Qualitative study based on primary data obtained through four focus groups analysis (three teenager groups between 13 and 15 y and 1 parent/teacher group)...
November 3, 2016: Revista Española de Salud Pública
https://www.readbyqxmd.com/read/27803949/usability-and-workflow-evaluation-of-rheumatic-disease-activity-ready-a-mobile-application-for-rheumatology-patients-and-providers
#20
Po-Yin Yen, Barbara Lara, Marcelo Lopetegui, Aseem Bharat, Stacy Ardoin, Bernadette Johnson, Puneet Mathur, Peter J Embi, Jeffrey R Curtis
BACKGROUND: RhEumAtic Disease activitY (READY) is a mobile health (mHealth) application that aims to create a shared platform integrating data from both patients and physicians, with a particular emphasis on arthritis disease activity. METHODS: We made READY available on an iPad and pilot implemented it at a rheumatology outpatient clinic. We conducted 1) a usability evaluation study to explore patients' and physicians' interactions with READY, and 2) a time motion study (TMS) to observe the clinical workflow before and after the implementation...
November 2, 2016: Applied Clinical Informatics
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