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Ischemic optic neuropathy

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https://www.readbyqxmd.com/read/29338755/hyperhomocysteinemia-in-bilateral-anterior-ischemic-optic-neuropathy-after-conventional-coronary-artery-bypass-graft-a-case-report
#1
A Niro, G Sborgia, A Sborgia, G Alessio
BACKGROUND: The incidence of anterior ischemic optic neuropathy after coronary artery bypass graft procedures ranges from 1.3 to 0.25%. The mechanisms of anterior ischemic optic neuropathy after cardiovascular procedures remain undefined but many systemic and related-to-surgery risk factors could underlie anterior ischemic optic neuropathy. In this case, we report a rare presentation of a bilateral anterior ischemic optic neuropathy after coronary artery bypass graft and speculate on the preoperative hyperhomocysteinemia as an independent risk factor for anterior ischemic optic neuropathy...
January 17, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29330063/risk-of-ischemic-kidney-injury-in-patients-with-nonarteritic-anterior-ischemic-optic-neuropathy-a-nationwide-population-based-study
#2
Ju-Yeun Lee, Kyung-Ah Park, Sei Yeul Oh
PURPOSE: To investigate the risk of acute tubular necrosis (ATN) in patients with nonarteritic anterior ischemic optic neuropathy (NAION). DESIGN: Population-based cohort study METHODS: This is a nationwide, population-based, retrospective study using data from the Korean national health claims database from 2011 through 2015. Patients with NAION and randomly selected control subjects from the entire Korean population were enrolled. A log rank analysis was used to evaluate a risk of ATN in the group of patients with NAION (study group) compared to an age-, sex-, and comorbidities-matched control group...
January 9, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29320503/pattern-of-peripapillary-capillary-density-loss-in-ischemic-optic-neuropathy-compared-to-that-in-primary-open-angle-glaucoma
#3
Masoud Aghsaei Fard, Yanin Suwan, Sasan Moghimi, Lawrence S Geyman, Toco Y Chui, Richard B Rosen, Robert Ritch
PURPOSE: Both non-arteritic anterior ischemic optic neuropathy (NAION) and primary open-angle glaucoma (POAG) damage retinal ganglion cell axons, which are perfused by the radial peripapillary capillaries. To evaluate the pattern of ischemia, we compared peripapillary capillary density (PCD) in NAION eyes to POAG eyes matched for visual field mean deviation and retinal nerve fiber layer thickness. METHODS: 31 chronic NAION (>6 months after the acute event) and unaffected fellow eyes (31 subjects), 42 moderate and severe POAG eyes (27 subjects), and 77 control eyes (46 healthy subjects) were imaged with a commercial optical coherence tomography angiography system (AngioVue, Avanti RTVue-XR, Optovue, CA) at two academic institutions...
2018: PloS One
https://www.readbyqxmd.com/read/29290461/oculomotor-palsy-in-diabetics
#4
H Lajmi, W Hmaied, W Ben Jalel, Z Chelly, A Ben Yakhlef, F Ben Zineb, L El Fekih
INTRODUCTION: Oculomotor palsy is one of the most frequent neuro-ophthalmologic complications of diabetic patients. It generates less interest in the literature than the other ocular manifestations. Our goal was to study the clinical, epidemiological, therapeutic and prognostic characteristics of oculomotor palsy in the diabetic. METHODS: This is a retrospective study of 24 diabetic patients with oculomotor palsy. The ophthalmological examination emphasized ocular motility...
December 28, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29260500/baseline-demographics-clinical-features-and-treatment-protocols-of-240-patients-with-optic-neuropathy-experiences-from-a-neuro-ophthalmological-clinic-in-the-aegean-region-of-turkey
#5
Omer Karti, Dilek Top Karti, İlay Hilal Kilic, Figen Gokcay, Nese Celebisoy
PURPOSE: To analyze the demographic patterns, clinical characteristics, and treatment protocols of optic neuropathies. MATERIALS AND METHODS: The hospital data of patients with optic neuropathy admitted to the Department of Neuro-ophthalmology in a tertiary referral center in Turkey between January 2010 to January 2017 were retrospectively analyzed. Demographic patterns, clinical features, treatment protocols, and the natural disease courses were assessed. RESULTS: The total number of patients with optic neuropathy seen over this period was 240, which consist of 43 with idiopathic optic neuritis (17...
December 19, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/29260067/severe-bilateral-optic-nerve-and-retinal-hypoperfusion-in-a-patient-with-acute-respiratory-distress-syndrome-and-septic-shock
#6
Wei Gui, Erika Tanaka Friesen, Laura Bonelli, Ye Elaine Wang, Anthony C Arnold
Purpose: To report a case of bilateral central retinal artery occlusion with both anterior and posterior ischemic optic neuropathy. Observations: A 65-year-old Caucasian woman presented with acute respiratory distress syndrome and septic shock. After treatment with vasopressors and prolonged prone positioning, she was noted to be bilaterally completely blind on hospitalization day 12. Evaluation revealed evidence of bilateral central retinal artery occlusion and bilateral ischemic optic neuropathy...
June 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29260058/a-case-of-non-arteritic-anterior-ischemic-optic-neuropathy-after-completion-of-harvoni-therapy
#7
Niranjan Manoharan, Prem Sagar Subramanian
Purpose: To report the first reported case of non-arteritic anterior ischemic optic neuropathy (NAION) associated with the use of Harvoni (Gilead Sciences, Foster City, CA, USA), a newly approved treatment for Hepatitis C. Observations: We report a case of NAION in a hepatitis C patient who completed Harvoni therapy just prior to presentation. Harvoni was suspected to be the causative agent given a lack of NAION risk factors in an otherwise healthy young patient...
June 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29243035/systemic-lupus-erythematosus-and-ocular-involvement-an-overview
#8
REVIEW
Rosanna Dammacco
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease of undefined etiology and with remarkably heterogeneous clinical features. Virtually any organ system can be affected, including the eye. SLE-related eye involvement can be diagnosed in approximately one-third of the patients and is usually indicative of disease activity. An early diagnosis and the adoption of suitable therapeutic measures are necessary to prevent sight-threatening consequences, especially in patients with juvenile SLE. Periocular lesions, such as eyelid involvement and orbital inflammation, are relatively rare and, in case of orbital masses, may require a biopsy control...
December 14, 2017: Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/29231347/-study-on-electroacupuncture-along-the-visual-conductive-pathway-for-ocular-cell-apoptosis-in-anterior-ischemic-optic-neuropathy
#9
Ying Wang, Hui Guo, Zide Zhao, Lina Yu, Peng Bai
OBJECTIVE: To study the protective effect of electroacupuncture (EA) along the visual conductive pathway for the optic nerve tissue of anterior ischemic optic neuropathy (AION) in terms of the structure and apoptosis. METHODS: The AION model of right eye was established with laser in 48 New Zealand white ear rabbits. All rabbits were randomly divided into a model group, an acupuncture group and an acupuncture combined with EA group, 16 rabbits in each one. Other 16 normal left eyes were selected as a blank group...
August 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29227256/-psychogenic-factors-in-the-pathogenesis-of-anterior-ischemic-optic-neuropathy-review
#10
B Ahmadyarova, Y Shusterov, M Lyubchenko
The purpose of this systematic review is to describe the influence of psychogenic factors on the pathogenesis and course of anterior ischemic optic neuropathy (AION). Analysis of randomized clinical trials published in the journal indexed in PubMed in the period from 1978 to 2016, devoted to the study of the influence of various factors on the epidemiology, pathogenesis and course of AION. The review of the literature presents basic information on the psychogenic factors that affect the course of AION and the areas of clinical application of the data under study...
November 2017: Georgian Medical News
https://www.readbyqxmd.com/read/29222573/incidence-and-causes-of-overdiagnosis-of-optic-neuritis
#11
Leanne Stunkel, Nathan H Kung, Bradley Wilson, Collin M McClelland, Gregory P Van Stavern
Importance: Diagnostic error is an important source of medical error. Overdiagnosis of optic neuritis may prompt unnecessary and costly diagnostic tests, procedures, and treatments. Objective: To assess the incidence of and characterize factors contributing to overdiagnosis of acute optic neuritis. Design, Setting, and Participants: In this retrospective clinic-based cross-sectional study of new patient encounters, 122 patients referred for acute optic neuritis at a university-based Midwestern neuro-ophthalmology clinic between January 2014 and October 2016 were studied...
December 7, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29215388/case-of-bilateral-sequential-nonarteritic-ischemic-optic-neuropathy-after-rechallenge-with-sildenafil
#12
Anastasia Neufeld, Judith Warner
No abstract text is available yet for this article.
December 5, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29195504/blinded-by-zika-a-missed-hiv-diagnosis-that-resulted-in-optic-neuropathy-and-blindness-a-case-report
#13
Tiffany Hirschel, Heimo Steffen, Victor Pecoul, Alexandra Calmy
BACKGROUND: Typical symptoms of an acute human immunodeficiency virus (HIV) infections like fever and rash are not specific and can be caused by a multitude of other pathogens, such as Zika or rickettsiosis. Up to 30% of primary HIV infection do not present with the typical flu-like symptoms and thus represent a diagnostic challenge. In this report, we describe a rare case of optic neuropathy as the initial presentation of primary HIV infection, which resulted in irreversible blindness...
December 1, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29191536/the-enigma-of-orbital-compartment-syndrome-after-lumbar-spine-surgery-in-the-prone-position-case-report-and-literature-review
#14
Jorge Luiz Amorim Correa, Marcus André Acioly
Perioperative visual loss (POVL) after spinal surgery is a devastating complication for both the patient and the surgical team. Two major causes are known: ischemic optic neuropathy (ION) and central retinal artery occlusion (CRAO). The traditional understanding of CRAO has been consistently related to the occurrence of periocular trauma and signs of increased intraorbital pressure in addition to visual loss. Such orbital signs are, however, not a feature of any common POVL syndrome. A 55-year-old woman underwent prolonged lumbar decompression and fusion for spinal stenosis under general anesthesia in the prone position...
November 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29184605/the-risk-of-ischemic-optic-neuropathy-post-phacoemulsification-cataract-surgery
#15
Mousa Victor Al-Madani, Nancy Khalaf Al-Raqqad, Naser Abdallah Al-Fgarra, Amal Mousa Al-Thawaby, Ahmed Abdelra'of Jaafar
Introduction: The aim was to study the risk of non arteritic ischemic optic neuropathy after phacoemulsification cataract surgery. Methods: This study was conducted at King Hussein Medical Center during the period between January 2015 and July 2016. Patients attending ophthalmology clinic complaining of decreased vision due to lens opacity were evaluated. Patients were divided into two groups. First group included patients with no medical illness and second group included patients with diabetes mellitus, hypertension or hyperlipidemia...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/29168365/evaluation-of-choroidal-thickness-measurements-in-pediatric-obstructive-sleep-apnea-syndrome-patients
#16
Cem Bayraktar, Ali Şimşek
Bayraktar C, Şimşek A. Evaluation of choroidal thickness measurements in pediatric obstructive sleep apnea syndrome patients. Turk J Pediatr 2017; 59: 62-67. Choroidal vascular impairment and obstructive sleep apnea syndrome (OSAS) related disorders have been shown in adults, but there have been no investigations with regard to the choroidal thickness measurements in children with OSAS. Our aim was to investigate this relationship in the early childhood period, which correlates with OSAS peak incidence due to adenotonsillar enlargement...
2017: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/29144506/soluble-p-selectin-promotes-retinal-ganglion-cell-survival-through-activation-of-nrf2-signaling-after-ischemia-injury
#17
Kishan Kapupara, Yao-Tseng Wen, Rong-Kung Tsai, Shun-Ping Huang
Retinal ischemic injuries play an important role in the pathogenesis of several eye disorders. Inflammation and oxidative stress are key players in ischemic injuries. Following retinal ischemia, vascular endothelial cells and leukocytes express several inflammatory adhesion receptors, such as selectins and cell adhesion molecules. P-selectin stimulates leukocyte recruitment to platelet aggregates and has an important role in vascular homeostasis and inflammatory leukocyte extravasation. Soluble P-selectin can be neuroprotective through competitive binding to the receptors of endogenous P-selectin molecules...
November 16, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/29140815/neuroimaging-diagnostic-and-monitoring-approaches-in-ophthalmology
#18
Bart K Chwalisz, Marc A Bouffard, Sashank Prasad, Dean M Cestari
PURPOSE OF REVIEW: We review new applications of optical coherence tomography (OCT) technology in neuro-ophthalmology. We also describe new technologies for visualizing the extracranial vessels in the diagnosis of giant cell arteritis (GCA). RECENT FINDINGS: Newer OCT modalities are expanding the evaluation of the optic disc, and are being applied to a number of neurologic conditions such as demyelinating and neurodegenerative disease. Swept-source OCT and enhanced-depth imaging OCT are refining the fine-grained analysis of the optic nerve head in the diagnosis of papilledema and optic nerve drusen...
February 2018: Current Opinion in Neurology
https://www.readbyqxmd.com/read/29135814/neuro-ophthalmology-at-a-tertiary-eye-care-centre-in-india
#19
Rebika Dhiman, Digvijay Singh, Shiva P Gantayala, Vaitheeswaran L Ganesan, Pradeep Sharma, Rohit Saxena
BACKGROUND: Neuro-ophthalmology as a specialty is underdeveloped in India. The aim of our study was to determine the spectrum and profile of patients presenting to a tertiary eye care center with neuro-ophthalmic disorders. METHODS: A retrospective hospital-based study was conducted, and records of all patients seen at the neuro-ophthalmology clinic of Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India, over a 1-year period were retrieved and evaluated...
November 9, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29130572/ischemic-optic-neuropathy-in-a-dog-with-acute-bilateral-blindness-and-primary-systemic-hypertension
#20
L Mari, R Stavinohova, E Dominguez, J Premont, J Oliver, L De Risio
A 6-year-old neutered female Jack Russell terrier was investigated for sudden onset prechiasmatic bilateral blindness, left circling, reduced proprioception in the right pelvic limb and right facial allodynia. Electroretinography was normal. Magnetic resonance imaging (MRI) examination revealed that the right optic nerve and the optic chiasm were hyperintense on diffusion weighted imaging and hypointense on apparent diffusion coefficient map consistent with ischemic optic neuropathy. A concurrent lacunar infarct was detected in the left rostral colliculus...
November 12, 2017: Journal of Veterinary Internal Medicine
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