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Orbital tumor

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https://www.readbyqxmd.com/read/27913089/a-combined-one-stage-surgical-approach-of-orbital-tumor-debulking-lid-reconstruction-and-ptosis-repair-in-children-with-orbitotemporal-neurofibromatosis
#1
Shay Keren, Gad Dotan, Ran Ben-Cnaan, Leah Leibovitch, Igal Leibovitch
BACKGROUND AND AIM: To describe a series of children with neurofibromatosis type 1 (NF1) and a plexiform neurofibroma of the orbit with ptosis who underwent a combined one-stage surgery for tumor debulking, lid reconstruction, and ptosis repair. METHODS: A retrospective review of 6 cases of combined one-step surgeries for orbital plexiform neurofibroma with ptosis. RESULTS: The study included 6 children (4 boys, mean age 3.4 years). Follow-up time was at least 9 months...
November 11, 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/27906855/periocular-basal-cell-carcinoma-predictors-for-recurrence-and-infiltration-of-the-orbit
#2
Alena Furdova, Pavol Lukacko
PURPOSE: To present the proportion of patients with periocular basal cell carcinoma (BCC) who underwent orbital exenteration and to evaluate the significance of the risk factors. DESIGN: Retrospective, comparative, interventional case series. METHODS: Data of all patients with BCC between 2008 and 2014 were reviewed for patient demographics, previous treatment options, tumor localization, and histopathologic subtype. RESULTS: In group of 256 patients, orbital exenteration underwent 7 patients (2...
November 30, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27905347/an-interesting-case-of-angiogenesis-in-cavernous-hemangioma
#3
Dipankar Das, Kasturi Bhattacharjee, Panna Deka, Harsha Bhattacharjee, Diva Kant Misra, Akanksha Koul, Deepika Kapoor, Apurba Deka
Cavernous hemangioma is the most common orbital tumor in adult. There is lot of literatures for clinicopathological features of this tumor. These tumors had been studied for the model of angiogenesis in many of the experimental setups. We present a case of 34-year-old male with this tumor in the left eye with computerized tomography evidence. Postsurgical laboratory findings gave interesting evidence of tumor angiogenesis with tumor endothelial cells and sprouting of the small vessels endothelial cells. Podosome rosette could be conceptualized from the characteristic patterns seen in the tumor...
October 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27902954/multi-recurrent-invasive-ameloblastoma-a-surgical-challenge
#4
Fatemah Faras, Fawaz Abo-Alhassan, Yona Israël, Barbara Hersant, Jean-Paul Meningaud
INTRODUCTION: Ameloblastomas are rare head and neck tumors, and yet the most common odontogenic neoplasms. They account for 1% and 11% of all head and neck and odontogenic tumors respectively. Embryologically, they originate from remnants of odontogenic epithelium. Their aggressive, destructive nature, as well as their anticipated high rate of recurrence, even after en bloc resection, poses a surgical predicament. PRESENTATION: We present a case of a 56 year-old Asian female with a multi-recurrent invasive ameloblastoma...
November 21, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27874325/mixed-beam-murine-harderian-gland-tumorigenesis-predicted-dose-effect-relationships-if-neither-synergism-nor-antagonism-occurs
#5
Nopphon Siranart, Eleanor A Blakely, Alden Cheng, Naval Handa, Rainer K Sachs
Complex mixed radiation fields exist in interplanetary space, and little is known about their late effects on space travelers. In silico synergy analysis default predictions are useful when planning relevant mixed-ion-beam experiments and interpreting their results. These predictions are based on individual dose-effect relationships (IDER) for each component of the mixed-ion beam, assuming no synergy or antagonism. For example, a default hypothesis of simple effect additivity has often been used throughout the study of biology...
November 22, 2016: Radiation Research
https://www.readbyqxmd.com/read/27866322/rare-case-of-an-ancient-craniofacial-osteosarcoma-with-probable-surgical-intervention
#6
Erika Molnár, Michael Schultz, Tyede H Schmidt-Schultz, Antónia Marcsik, Krisztina Buczkó, Péter Zádori, Gergely Biró, Zsolt Bernert, Daniel Baumhoer, Tamás Hajdu
Osteosarcoma is the most common primary malignant bone tumor both today and in antiquity. Nevertheless, it is a comparatively rare tumor. This paper describes a case of a highly aggressive craniofacial lesion from the 11th-12th centuries AD, most likely representing osteosarcoma. During the paleopathological study, macroscopic, endoscopic, radiological, scanning-electron and light microscopic investigations were performed. The skull of the approximately 40-50 year-old female revealed several pathological findings...
November 19, 2016: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/27861307/epibulbar-plasmacytoma-masquerading-as-subconjunctival-hemorrhage-in-a-patient-with-multiple-myeloma
#7
Amanda Bradley, Amy Estes, Lane Ulrich, Dilip Thomas, David Gay
PURPOSE: We report a 75-year-old woman with a history of multiple myeloma immunoglobulin D (IgD) variant, who presented with an epibulbar plasmacytoma masquerading as a subconjunctival hemorrhage. METHODS: Magnetic resonance imaging of the brain and orbits with and without contrast was obtained and surgical biopsy of the subconjunctival lesion was performed; histopathology confirmed the diagnosis of plasmacytoma. RESULTS: Subconjunctival biopsy revealed a plasma cell neoplasm infiltrate in the episcleral layer...
November 16, 2016: Cornea
https://www.readbyqxmd.com/read/27857873/superolateral-orbitotomy-for-intraorbital-tumors-comparison-with-the-conventional-approach
#8
Mine Seiichiro, Higuchi Yoshinori, Horiguchi Kentaro, Saeki Naokatu
Objectives This study aims to compare the surgical and functional outcomes of superolateral orbitotomy (group A) and conventional superior orbitotomy (group B) for benign orbital tumors. Design A retrospective review of 31 consecutive orbital tumor surgeries with the fronto-orbital approach was conducted. Setting Procedures were performed at two institutions by a single surgeon. Participants A total of 31 orbital tumor patients participated in this study. Overall, 11 intraconal and 2 extraconal tumors in group A and 11 intraconal and 7 extraconal tumors in group B were resected by superolateral orbitotomy, respectively...
December 2016: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/27853024/extraskeletal-osteosarcoma-of-the-orbit-a-clinicopathologic-case-report-and-review-of-literature
#9
V M D S de Maeyer, P A F A Kestelyn, Akash D Shah, C M Van Den Broecke, H G N Denys, C E Decock
Primary extraskeletal osteosarcoma (EOS) is an extremely rare malignancy. In this report, the clinical course of a 32-year-old man presenting with proptoses is described. Medical history included Hirschsprung disease (HD), horseshoe kidney, azoospermia, and vertebral anomalies. Imaging of the orbit showed an oval, well-defined heterogeneous mass adjacent to the lateral wall of the orbit. The patient underwent a lateral orbitotomy and complete excision of the mass. The mass was not attached to the bone. Histopathologic and immunohistochemical examination confirmed the diagnosis of an EOS...
September 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27847741/retiform-hemangioendothelioma-in-the-infratemporal-fossa-and-buccal-area-a-case-report-and-literature-review
#10
Il-Kyu Kim, Hyun-Young Cho, Bum-Sang Jung, Sang-Pill Pae, Hyun-Woo Cho, Ji-Hoon Seo, Seung-Hoon Park
We report a case of retiform hemangioendothelioma (RH) located in the infratemporal fossa and buccal area in a 13-year-old Korean boy. The tumor originated from the sphenoid bone of the infratemporal fossa area and spread into the cavernous sinus, orbital apex, and retro-nasal area with bone destruction of the pterygoid process. Tumor resection was conducted via Le Fort I osteotomy and partial maxillectomy to approach the infratemporal fossa and retro-nasal area. The diagnosis of RH was confirmed after surgery...
October 2016: Journal of the Korean Association of Oral and Maxillofacial Surgeons
https://www.readbyqxmd.com/read/27844410/the-great-mimicker-metastatic-breast-carcinoma-to-the-head-and-neck-with-emphasis-on-unusual-clinical-and-pathologic-features
#11
Dikson Dibe Gondim, Rebecca Chernock, Samir El-Mofty, James S Lewis
Distant metastases are relatively common in breast cancer, but spread to the head and neck region is uncommon and can be diagnostically challenging. Pathology databases of two academic hospitals were searched for patients. The diagnoses were by morphologic comparison with the primary breast specimen (when available) or through the use of immunohistochemical stains characteristic of breast carcinoma (cytokeratin 7, mammaglobin, GCDFP15, and/or GATA3 positive-excluding new primary tumors at the respective head and neck sites)...
November 14, 2016: Head and Neck Pathology
https://www.readbyqxmd.com/read/27831979/large-frontoorbital-osteoma-causing-ptosis
#12
Nurdoğan Ata, Mesut Sabri Tezer, Ersen Koç, Gültekin Övet, Ömer Erdur
Osteomas are the most frequent benign tumor of the paranasal sinuses. The commonest site is the frontal sinus but intraorbital extension of frontal osteoma is rare. Here, the authors report a 15-year-old adolescent boy who presented with left superior orbital rim swelling and ptosis. Waters radiography and computed tomographic scan revealed a bone density mass in the left frontal sinus with upper orbital wall extension. The tumor was removed via open eyebrow incision. The histopathologic evaluation was consistent with osteoma...
November 9, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27826936/ocular-surface-squamous-neoplasia-as-the-initial-presenting-sign-of-human-immunodeficiency-virus-infection-in-60-asian-indian-patients
#13
Swathi Kaliki, Saurabh Kamal, Saba Fatima
PURPOSE: To study the importance of routine human immunodeficiency virus (HIV) screening in patients with ocular surface squamous neoplasia (OSSN) and describe their clinical features and management. METHODS: Retrospective study. RESULTS: Of 228 cases of OSSN screened for HIV by enzyme-linked immunosorbent assay, 86 (38%) patients were HIV positive. Of these 86 patients, 60 (70%) were unaware of their HIV-positive status prior to HIV screening...
November 8, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27818811/first-report-of-aids-related-burkitt-s-lymphoma-presenting-as-bilateral-orbital-masses
#14
Monica Alves de Almeida, Juliana Nesi Cardoso Migliano Porto, Ana Carolina de Brito Lyra, Luiz Arthur Calheiros Leite, Rodrigo Panno Basilio-de-Oliveira, Rogério Neves-Motta, Andréa Ramos Correa, Fernando Raphael de Almeida Ferry, Walter de Araujo Eyer-Silva, Ronaldo Grechi Pacheco
Burkitt's lymphoma (BL) is an aggressive B-cell non-Hodgkin's lymphoma and one of the fastest growing tumors in humans. It is an acquired immunodeficiency syndrome- (AIDS-) defining disease and occurs with relatively preserved CD4 cell counts. It rarely affects the orbital region in the setting of AIDS. We report unusual presentation of a fatal case of AIDS-associated BL in a 42-year-old female patient with severe CD4 cell depletion who presented with dramatic fast growing (within days) bilateral orbital masses leading to striking facial deformities...
2016: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/27818205/histopathologic-analysis-of-trans-vitreal-fine-needle-aspiration-biopsy-needle-tracts-for-uveal-melanoma
#15
Ryan S Kim, Patricia Chevez-Barrios, Maria E Bretana, Tien P Wong, Bin S Teh, Amy C Schefler
PURPOSE: Perform the first in vivo examination of fine needle aspiration biopsy scleral tracts to determine the incidence of iatrogenic extension of tumor cells. DESIGN: A prospective, consecutive, observational case series. METHODS: Setting: Clinical/surgical setting at Retina Consultants of Houston and Houston Methodist Hospital, Houston, TX. PARTICIPANTS: Ten patients who were scheduled for enucleation as primary treatment for uveal melanoma...
November 3, 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27811130/impact-of-neuroradiology-based-peer-review-on-head-and-neck-radiotherapy-target-delineation
#16
S Braunstein, C M Glastonbury, J Chen, J M Quivey, S S Yom
BACKGROUND AND PURPOSE: While standard guidelines assist in target delineation for head and neck radiation therapy planning, the complex anatomy, varying patterns of spread, unusual or advanced presentations, and high risk of treatment-related toxicities produce continuous interpretive challenges. In 2007, we instituted weekly treatment planning quality assurance rounds as a joint enterprise of head and neck radiation oncology and neuroradiology. Here we describe its impact on head and neck radiation therapy target delineation...
November 3, 2016: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/27800245/chemotherapy-in-retinoblastoma-current-approaches
#17
REVIEW
Özge Yanık, Kaan Gündüz, Kıvılcım Yavuz, Nurdan Taçyıldız, Emel Ünal
Retinoblastoma (RB) is the most common childhood malignant intraocular tumor. Although enucleation and external beam radiotherapy have been historically used, today the most commonly used eye-sparing approach is chemotherapy. Chemotherapy can be used in both intraocular and extraocular RB cases. Chemotherapeutic agents may be applied in different ways, including systemic, subconjunctival, intra-arterial and intravitreal routes. The main purposes of application of systemic therapy are to reduce the tumor size for local treatment (chemoreduction), or to reduce the risk of metastasis after enucleation surgery (adjuvant therapy)...
December 2015: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/27799732/orbital-exenteration-in-immunodeficiency-virus-infected-patients
#18
Kagmeni Giles, Yannick Bilong, Nomo Arlette, Nanfack Chantal, Bella Assumpta Lucienne
BACKGROUND: Orbital exenteration (OE) is a disfiguring procedure most commonly performed for locally advanced and potentially life-threatening periorbital malignancies. METHODS: We retrospectively reviewed records of 11 consecutive HIV patients who underwent OE for invasive orbital malignancy at our institution from January 2005 to December 2015. Patient demographic and clinic data and histopathology of the tumor were analyzed. RESULTS: There were eight (72...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27792048/primary-gliosarcoma-of-the-optic-nerve-a-unique-adult-optic-pathway-glioma
#19
Patrick J Cimino, Yevgeniy V Sychev, Luis F Gonzalez-Cuyar, Raghu C Mudumbai, C Dirk Keene
A 90-year-old woman presented with 1-year history of right-sided progressive proptosis, neovascular glaucoma, blindness, and worsening ocular pain. No funduscopic examination was possible because of a corneal opacity. Head CT scan without contrast demonstrated a heterogeneous 4.1 cm (anterior-posterior) by 1.7 cm (transverse) cylindrical mass arising in the right optic nerve and extending from the retrobulbar globe to the optic canal. She underwent palliative enucleation with subtotal resection of the orbital optic nerve and tumor...
October 11, 2016: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27790116/bilateral-choroidal-metastases-from-lung-adenocarcinoma-a-case-report
#20
Hasan Ergenc, Attila Onmez, Ezgi Oymak, Ramiser Tanriseven, Erkan Celik, Funda Ebru Onmez, Ali Tamer, Meltem Baykara
The most common malignancy of the eye is metastatic tumors, with choroidal metastases being the majority of them. In women, breast cancer is the most common cause of orbital metastases, and in men, it is lung cancer. Despite the fact that there are efficient treatment options for orbital metastases, the benefit of procedures to detect choroidal metastases is debatable due to the quick progression and poor prognosis of lung cancer. In choroidal metastases resulting from lung cancer, patients are usually presented with decreased sight...
September 2016: Case Reports in Oncology
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