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Orbital tumors

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https://www.readbyqxmd.com/read/29667174/impact-of-prior-cancer-history-on-the-overall-survival-of-patients-newly-diagnosed-with-cancer-a-pan-cancer-analysis-of-the-seer-database
#1
Huaqiang Zhou, Yan Huang, Zeting Qiu, Hongyun Zhao, Wenfeng Fang, Yunpeng Yang, Yuanyuan Zhao, Xue Hou, Yuxiang Ma, Shaodong Hong, Ting Zhou, Yaxiong Zhang, Li Zhang
The population of cancer survivors with prior cancer is rapidly growing. Whether a prior cancer diagnosis interferes with outcome is unknown. We conducted a pan-cancer analysis to determine the impact of prior cancer history for patients newly diagnosed with cancer. We identified 20 types of primary solid tumors between 2004 to 2008 in the Surveillance, Epidemiology, and End Results (SEER) database. Demographic and clinicopathologic variables were compared by chi-squared test and t-test as appropriate. The propensity score-adjusted Kaplan-Meier method and Cox proportional hazards models were used to evaluate the impact of prior cancer on overall survival (OS)...
April 18, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29657677/immunoglobulin-g4-related-disease-an-update
#2
REVIEW
Abdullah Al-Mujaini, Murtadha Al-Khabori, Kashinatha Shenoy, Upender Wali
Immunoglobulin G4-related disease (IgG4-RD) is an increasingly recognized immune-mediated condition comprised of a collection of disorders that share specific pathological, serological, and clinical features. IgG4-RD is a fibroinflammatory condition with a tendency to form tumors with inflammatory infiltrate with IgG4 rich plasma cells and elevation of serum IgG4, which may affect virtually every organ and tissue. IgG4-related ophthalmic disease may present as dacryoadenitis, myositis, or involvement of other orbital tissue...
March 2018: Oman Medical Journal
https://www.readbyqxmd.com/read/29651818/effects-on-periocular-tissues-after-proton-beam-radiation-therapy-for-intraocular-tumors
#3
Youn Joo Choi, Tae Wan Kim, Suzy Kim, Hokyung Choung, Min Joung Lee, Namju Kim, Sang In Khwarg, Young Suk Yu
BACKGROUND: To present our experience on orbital and periorbital tissue changes after proton beam radiation therapy (PBRT) in patients with intraocular tumors, apart from treatment outcomes and disease control. METHODS: Medical records of 6 patients with intraocular tumors who had been treated with PBRT and referred to oculoplasty clinics of two medical centers (Seoul National University Hospital and Seoul Metropolitan Government-Seoul National University Boramae Medical Center) from October 2007 to September 2014 were retrospectively reviewed...
April 16, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29649644/endoscopic-transseptal-approach-with-a-bilateral-nasoseptal-flap-in-challenging-skull-base-tumors
#4
Do Hyun Kim, Yong-Kil Hong, Sin-Soo Jeun, Jae-Sung Park, Soo Whan Kim, Jin Hee Cho, Yong Jin Park, Sung Won Kim
OBJECTIVE: To examine the utility of an endoscopic transseptal approach and the creation of a bilateral nasoseptal flap using a two-nostrils/four-hands technique in patients with challenging skull-base tumors. METHODS: The medical records of patients operated on via an endoscopic transseptal approach between 2009 and 2017 were retrospectively reviewed. Two patients with ossifying fibroma, two with orbital hemangioma, two with trigeminal nerve schwannoma, and one patient each with juvenile angiofibroma, meningioma, and myxofibrosarcoma were included in the study...
April 9, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29643671/role-of-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-in-various-orbital-malignancies
#5
Aravintho Natarajan, Piyush Chandra, Nilendu Purandare, Archi Agrawal, Sneha Shah, Ameya Puranik, Venkatesh Rangarajan
Orbital swelling comprises wide spectrum of pseudotumors, benign and malignant tumor. Malignant tumor may be primary or secondary tumor, and they constitute about 36% of orbital tumors in adult. Fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) scan is extensively used in hematological malignancies and in solid tumors for staging, treatment response, and restaging. Recently, the use of FDG-PET/CT in orbital malignancies has gained importance. The aim of this pictorial essay is to illustrate few important orbital malignancies detected in F-18 FDG-PET/CT and discuss its role in assessing the primary lesion and associated systemic finding...
April 2018: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/29643662/retinoblastoma-in-an-adult
#6
Vasudha Garg, Ashumi Gupta, Sonam K Pruthi, Pratima Khare
Retinoblastoma is a rare malignant tumor of the retina usually seen in children before 5 years of age. The tumor is extremely rare in adults. We report here an unusual case of retinoblastoma in a 55-year-old adult female who presented to us with an orbital mass at a late stage of the disease. Detailed laboratory investigations and imaging studies could not make a precise diagnosis. The treating ophthalmologist suspected primary intraocular tumor, metastatic carcinoma, malignant melanoma, or lymphoma and referred the patient for fine needle aspiration cytology (FNAC)...
April 2018: Journal of Cytology
https://www.readbyqxmd.com/read/29626183/primary-basosquamous-carcinoma-of-the-lower-eyelid-with-ocular-invasion-a-case-report
#7
Georgios Ouilson Papadopoulos, Eleni Charitonidi, Nikolaos Filippou, Domna Fanidou, Dimitrios Filippou, Panagiotis Scandalakis
INTRODUCTION: Ocular invasion is extremely rare for a primary eyelid Basosquamous Carcinoma (BSC). It can however occur in neglected cases if the clinical signs are overseen and the BSC is misdiagnosed for a less aggressive skin carcinoma. MATERIALS AND METHODS: A 58-year-old man suffering from an inferior eyelid BSC that had been neglected for 7 years was referred to our clinic. A local infiltration of the maxillary sinus and the contents of the orbit by the tumor was discovered, and he was managed with a left orbital exenteration and resection of the involved orbital bone...
March 26, 2018: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/29609437/intraosseous-hemangioma-of-the-orbit
#8
June Seok Choi, Yong Chan Bae, Gyu Bin Kang, Kyung-Un Choi
Intraosseous hemangioma is an extremely rare tumor that accounts for 1% or fewer of all osseous tumors. The most common sites of its occurrence are the vertebral column and calvaria. Occurrence in a facial bone is very rare. The authors aim to report a case of the surgical treatment of intraosseous hemangioma occurring in the periorbital region, which is a very rare site of occurrence and to introduce our own experiences with the diagnosis and treatment of this condition along with a literature review. A 73-year-old male patient visited our hospital with the chief complaint of a mass touching the left orbital rim...
March 2018: Archives of Craniofacial Surgery
https://www.readbyqxmd.com/read/29606119/invasive-meningococcal-disease-due-to-a-non-capsulated-neisseria-meningitidis-strain-in-a-patient-with-igg4-related-disease
#9
Shun Kurose, Kyoko Onozawa, Hiroshi Yoshikawa, Kenichiro Yaita, Hideyuki Takahashi, Nobuyuki Shimono, Yoji Nagasaki
BACKGROUND: Invasive Meningococcal Disease (IMD) is a rare and critical disease in Japan. Most of these cases are caused by capsulated Neisseria meningitidis strains. Non-capsulated (non-typable) strains are considered relatively low-pathogenic and can colonize in the nasopharynx of healthy children and young adults. As far as could be ascertained, only twelve IMD cases due to non-capsulated strains have been reported in the literature. No clear risk factors could be identified in a literature review (unknown or immunocompetent, seven cases; C6 deficiency, three cases)...
April 2, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29606049/transbasal-versus-endoscopic-endonasal-versus-combined-approaches-for-olfactory-groove-meningiomas-importance-of-approach-selection
#10
James K Liu, Nicole A Silva, Ilesha A Sevak, Jean Anderson Eloy
OBJECTIVE There has been much debate regarding the optimal surgical approach for resecting olfactory groove meningiomas (OGMs). In this paper, the authors analyzed the factors involved in approach selection and reviewed the surgical outcomes in a series of OGMs. METHODS A retrospective review of 28 consecutive OGMs from a prospective database was conducted. Each tumor was treated via one of 3 approaches: transbasal approach (n = 15), pure endoscopic endonasal approach (EEA; n = 5), and combined (endoscope-assisted) transbasal-EEA (n = 8)...
April 2018: Neurosurgical Focus
https://www.readbyqxmd.com/read/29603576/incidence-of-head-and-neck-cancer-in-children-a-danish-nationwide-study-from-1978-to-2014
#11
Christian Grønhøj, Lisa Hjalgrim, Kathrine K Jakobsen, Birgitte Charabi, Christian Mirian, Gunnar H Laier, Katalin Kiss, Catherine Rechnitzer, Jeppe Friborg, Christian von Buchwald, Thomas Hjuler
BACKGROUND: Pediatric head and neck malignancies are rare and only a few descriptive epidemiological studies have been published. Using unique nationwide registries, we report age-specific incidence rates of head and neck cancer (HNC) among children during four decades. METHODS: Data were obtained from the Danish Cancer Registry. We included children aged 0-14 years diagnosed between January 1, 1978 and December 31, 2014 with extra-orbital, nonskin and nonbone HNC...
March 30, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29589985/a-giant-dermoid-cyst-of-the-orbit
#12
Bipasha Mukherjee, Akruti Desai
To describe a unique case of a non-germinomatous germ cell tumor, a giant orbital dermoid, present in adulthood. A 31-year-old male presented in our clinic with gradual, painless, progressive proptosis in the left eye since 28 years associated with gradual loss of vision. The left eye showed gross proptosis. Ocular structures could not be made out. Computed tomography scan showed a well-circumscribed oval heterogeneous mixed solid and cystic lesion completely filling the left orbit with calcification. The differential diagnosis was that of either teratoma or optic nerve glioma...
March 28, 2018: Orbit
https://www.readbyqxmd.com/read/29588898/low-subfrontal-dural-opening-for-anterior-clinoid-meningioma
#13
Michael R Chicoine
Introduction  A variety of dural openings are described for frontal-temporal and cranio-orbital craniotomies. As with any surgical technique, the goal is to optimally and safely address the pathology, minimize normal anatomy disruption, and optimize postoperative recovery. This study reports a modified dural opening for frontal-temporal approaches which minimizes brain exposure while facilitating visualization for neoplastic and vascular lesions of the anterior clinoid, supra- and parasellar and adjacent regions...
April 2018: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/29588895/expanded-endoscopic-transsphenoidal-resection-of-tuberculum-sella-meningioma-invading-the-optic-canal
#14
Georgios Klironomos, Margherita Bruni, Amir R Dehdashti
A 61-year-old male patient presented with recurrent malignant meningioma involving the left optic canal and decreased vision from the left eye. The patient had undergone orbital exenteration on the right 2 years ago. The decision to treat the patient was made based on the significant vision deterioration and rapid tumor growth. Endoscopic transsphenoidal approach considered the most suitable route due to the inferomedial invasion of the optic canal. Gross total removal was achieved and the patient's vision improved postoperatively...
April 2018: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/29588883/resection-of-a-retrochiasmatic-craniopharyngioma-by-combined-modified-orbital-craniotomy-and-transnasal-endoscopic-techniques
#15
Nirav J Patel, Ian Dunn
A 20-year-old patient presented with hydrocephalus but intact vision and hormone function. The MRI showed a large seller, suprasellar and third ventricular mass. We chose a combined approach utilizing the translyvian, lamina terminals route, with a possible interhemispheric approach. But, we also utilized a transnasal endoscopic approach for the tumor that remained below the diaphragma sellae. The patient did well, with complete tumor resection via a staged approach, but did require hormone replacement. The link to the video can be found at: https://youtu...
April 2018: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/29587486/cyberknife-radiotherapy-for-orbital-metastases-a-single-center-experience-on-24-lesions
#16
Giulia Riva, Matteo Augugliaro, Gaia Piperno, Annamaria Ferrari, Elena Rondi, Sabrina Vigorito, Delia Ciardo, Roberto Orecchia, Barbara Alicja Jereczek-Fossa
OBJECTIVES: To evaluate the feasibility, in terms of acute toxicity and symptom control, of CyberKnife (Accuray, Sunnyvale, CA)-based stereotactic radiotherapy (CyberKnife-SRT) for metastatic orbital lesions. METHODS: This retrospective study included patients with symptomatic metastases wholly located within the orbit. Palliative radiation treatment was performed using CyberKnife image-guided technology. Gross tumor volume was defined on a pre-radiotherapy magnetic resonance imaging...
March 1, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29579639/generation-of-a-human-induced-pluripotent-stem-cell-line-vrfi001-a-from-orbital-adipose-tissue-of-a-bilateral-retinoblastoma-patient-with-heterozygous-rb1-gene-deletion
#17
Ambily Vincent, Vikas Khetan, Pukhraj Rishi, Ganesan Suganeswari, Subramanian Krishnakumar, Uma Maheswari Krishnan, Sowmya Parameswaran
Retinoblastoma (RB) is a pediatric intraocular tumor caused by mutations in retinoblastoma (RB1) gene. We have generated induced pluripotent stem cell line VRFi001-A from a bilateral retinoblastoma patient with heterozygous RB1 gene deletion. The iPSC line VRFi001-A retained the mutation and expressed pluripotency markers, had a normal karyotype and was capable of trilineage differentiation.
March 19, 2018: Stem Cell Research
https://www.readbyqxmd.com/read/29573857/-oculoplastic-complications-of-the-excision-of-meningiomas-with-orbital-extension
#18
N Stoll, P Paquis, M Lonjon, S Baillif, J Lagier
INTRODUCTION: Meningiomas with orbital extension are the most frequent benign orbital tumors. The few studies available on the postoperative complications of their excision focus on the postoperative evolution of proptosis, visual acuity and visual field deficits. The goal of our study was to highlight the oculoplastic complications secondary to their excision. MATERIAL AND METHOD: We identified all cases of meningiomas with orbital extension undergoing excision either neurosurgically or via an orbital approach in the ophthalmology and neurosurgery departments of Pasteur university medical center in Nice between February 2011 and January 2017...
March 21, 2018: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29564405/orbital-invasion-of-ameloblastoma-a-systematic-review-apropos-of-a-rare-entity
#19
REVIEW
Mohammad-Ali Abtahi, Alireza Zandi, Hassan Razmjoo, Sara Ghaffari, Seyed-Mojtaba Abtahi, Hamidreza Jahanbani-Ardakani, Zahra Kasaei, Samira Kasaei-Koupaei, Sepideh Sajjadi, Seyed-Ali Sonbolestan, Seyed-Hossein Abtahi
Purpose: Ameloblastoma is a non-encapsulated and slow-growing tumor with high recurrence rate. Orbital involvement by this neoplasm is an extremely rare entity. In this study, we present a systematic review on this situation along with clinical and paraclinical features of a case. Methods: An electronic search was conducted on major medical sources. Data of the cases in the literature in addition to our own case were extracted, summarized, and statistically analyzed...
March 2018: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/29563690/eyelid-sebaceous-gland-carcinoma-varied-presentations-and-reconstruction-outcome
#20
Syed Ali Raza Rizvi, Md Shahid Alam, Kafil Akhtar
PURPOSE: To analyze varying clinical presentations, histopathological features, and management outcome of sebaceous gland carcinoma (SGC) of the eyelid. MATERIALS AND METHODS: We retrospectively reviewed medical records of 30 patients with histologically proven cases of SGC of eyelid treated at tertiary care hospital. RESULTS: Patients were in the age group of 28-80 years, among which 18 (60%) were females and 12 (40%) were males. Mean follow-up period was 29...
January 2018: Oman Journal of Ophthalmology
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