keyword
https://read.qxmd.com/read/38537041/primary-basal-cell-carcinoma-of-the-caruncle-case-report-and-review-of-the-literature
#1
Elizabeth Cecilia Roque-Choque, Jorge Ramiro Villalobos-Espinoza, Isabel Silva-Ocas, Rosa Alvarado-Villacorta, Pedro Muro-Mansilla
We present a rare case of primary caruncle basal cell carcinoma (BCC), a condition with limited occurrences. Our patient, an 80-year-old woman without prior ocular pathological history, presented a 2x2mm pedunculated blackish nodular lesion on the caruncle of her left eye, without local conjunctival or cutaneous involvement. Histological analysis following complete excision confirmed the presence of basal cell carcinoma within the caruncle. Over a span of 30 months, no recurrence has been observed. While scant cases are documented in the literature, we conducted a review of these instances...
2024: Arquivos Brasileiros de Oftalmologia
https://read.qxmd.com/read/38534161/surgical-management-of-complex-skull-base-tumor-using-preoperative-multimodal-image-fusion-technology
#2
JOURNAL ARTICLE
Zhi-Heng Jian, Peng Chen, Yu Li, Chang-Chun Liao, Xin-Feng Yi, Run-Gen Zhan, Gang Chen
OBJECTIVE: To review our single-institution experience in the surgical management of complex skull base tumors using multimodal image fusion technology. METHODS: From October 2019 to January 2022, 7 cases of complex skull base tumors that performed preoperative multimodal image fusion in Zhuhai People's Hospital neurosurgery department were involved in this study. The image data were uploaded to the GE AW workstation. Corresponding image sequences were opened in the workstation to complete registration fusion and 3D reconstruction...
March 27, 2024: Journal of Craniofacial Surgery
https://read.qxmd.com/read/38534054/successful-treatment-of-refractory-orbital-plasmacytoma-with-chimeric-antigen-receptor-t-cell-therapy-a-case-report-and-review-of-the-literature
#3
JOURNAL ARTICLE
Rebecca Z Lin, Tracy Lu, Natalie Homer, Clara J Men
Orbital plasmacytoma is a rare plasma cell tumor that may arise as an aggressive form of extramedullary multiple myeloma. Treatment modalities include surgical excision, radiation, and chemotherapy. Chimeric antigen receptor T cell therapy is currently reserved for refractory disease. The authors present a case of a 69-year-old woman with an extensive orbital plasmacytoma refractory to multimodal therapy who was treated with idecabtagene vicleucel chimeric antigen receptor T cell therapy. Four days after infusion, the patient exhibited grade 1 cytokine release syndrome, which resolved with tocilizumab...
March 21, 2024: Ophthalmic Plastic and Reconstructive Surgery
https://read.qxmd.com/read/38534052/multispecialty-management-of-metastatic-colon-adenocarcinoma-involving-the-extraocular-muscles-primary-excision-and-simultaneous-treatment-of-strabismus-with-a-review-of-the-literature
#4
JOURNAL ARTICLE
Fereshteh Azad, Tassapol Singalavanija, Robert Beaulieu, Federica Mingardo, Steven M Archer, Victor Maurice Elner, Hakan Demirci
Metastatic colon adenocarcinoma involving the extraocular muscles is extremely rare. It usually develops following the diagnosis of the systemic disease and therefore, management and treatment require a multispecialty approach. Within this manuscript, we provide a summary of cases of orbital metastasis secondary to colon cancer. We further discuss a detailed case of a 42-year-old male patient who developed recent-onset diplopia in the left gaze. Orbital CT imaging showed a localized, well-circumscribed enlargement of the right medial rectus muscle...
March 21, 2024: Ophthalmic Plastic and Reconstructive Surgery
https://read.qxmd.com/read/38530952/a-case-series-of-choroidal-and-orbital-neuroendocrine-tumors-metastasis-2-patients-treated-with-prrt
#5
JOURNAL ARTICLE
Tony Zibo Zhuang, Chris Bergstrom, Bassel F El-Rayes, Walid L Shaib
Neuroendocrine tumors are rare cancers with heterogenous histologies, response to treatments and prognoses. Majority of these cancers originate in the gastrointestinal tract and metastasize to the liver. We are reporting 5 patients with low-grade neuroendocrine tumor disease with rare metastases to the choroids. Two of the patients were treated with peptide receptor radionuclide therapy (Lutitium-177). This is the first report confirming PRRT safety in patients with low grade NET with ocular metastases.
March 14, 2024: Pancreas
https://read.qxmd.com/read/38529002/superior-oblique-muscle-extramedullary-plasmacytoma-in-a-patient-with-multiple-myeloma-and-a-review-of-literature
#6
Amirreza Veisi, Kimia Daneshvar, Sadid Hooshmandi, Maryam Najafi, Peyman Mohammadi Torbati, Kiana Hassanpour
INTRODUCTION: Multiple myeloma (MM), a plasma cell malignancy, is a systemic disease affecting various body organs. Plasmacytoma of bone and extramedullary disease (EMD) are presentations of MM. EMD is usually the sign of a more aggressive form of the disease. Herein, we report a patient with refractory MM presenting with extramedullary plasmacytoma in the superior oblique (SO) muscle. CASE PRESENTATION: A 51-year-old female presented complaining of gradual protrusion of the left eye and ocular pain from 20 days prior...
2024: Case Reports in Ophthalmology
https://read.qxmd.com/read/38526143/distinguishing-spheno-orbital-metastatic-prostate-cancer-mimicking-a-meningioma-using-novel-18-f-psma-pet-ct-imaging
#7
JOURNAL ARTICLE
Yilin Feng, Carolina A Chiou, Anna M Stagner, Yuh-Shin Chang, Suzanne K Freitag
A 78-year-old man presented with acute-onset left temporal pain, eyelid swelling, and double vision. Computed tomography (CT) demonstrated a left sphenoid wing mass with extra-osseous intra-orbital and intracranial extension, thought to be a typical sphenoid wing meningioma by the primary team. The patient was admitted for an urgent craniotomy, which was planned for the following day. However, upon consultation with ophthalmic plastic surgery, concern was raised for an alternative diagnosis given the atypical timeline, inflammatory changes, and uncharacteristic imaging findings of mixed lytic and sclerotic bony changes without hyperostosis on CT and extensive peri-lesional dural thickening and enhancement on magnetic resonance imaging...
March 25, 2024: Orbit
https://read.qxmd.com/read/38524010/eye-plaque-brachytherapy-for-choroidal-malignant-melanoma-a-case-report-on-the-use-of-innovative-technology-to-expand-access-improve-practice-and-enhance-outcomes
#8
Paul Mobit, Claus Chunli Yang, Mary R Nittala, Rui He, Hiba Z Ahmed, Gary Shultz, Albert Lin, Srinivasan Vijayakumar
Our institute established an eye plaque interstitial brachytherapy (EPIBT) program in 2007 using the Collaborative Ocular Melanoma Study (COMS) eye plaque. In this case report, we demonstrated an eye plaque treatment planned and executed using Eye Physics Plaque (Los Alamitos, CA) for a 72-year-old male patient with an extra-large tumor with a maximum width of 18.6 mm and height of 13.7 mm. The use of a customized eye plaque, manufactured through three-dimensional (3D) printing, has empowered us to plan and administer treatment for this patient with uveal melanoma...
February 2024: Curēus
https://read.qxmd.com/read/38523992/a-calcifying-odontogenic-cyst-with-compound-odontoma-in-the-maxillary-sinus-a-case-report-in-a-pediatric-patient
#9
Rodrigo A Oliveira, Ana C Maurício, Maria L Sacramento, Jorge Pinheiro, Mariana Moreira
Calcifying odontogenic cysts (COCs) exhibit a diverse clinical course, commonly developing between the second and third decades of life, displaying no gender predilection. A 15-year-old female without medical history was under observation for a mixed lesion in the maxilla associated with an impacted tooth. She presented to the emergency department with sudden onset and worsening swelling of the left midface. Radiographic findings in the panoramic radiograph and a CT scan revealed a well-circumscribed mixed lesion localized in the left maxilla, extending into the left maxillary sinus and reaching the orbital floor...
February 2024: Curēus
https://read.qxmd.com/read/38522979/pediatric-orbital-and-skull-base-pathology
#10
REVIEW
Dominic Nistal, Amy Lee, Jacob Ruzevick
Pediatric orbital and skull base pathologies encompass a spectrum of inflammatory, sporadic, syndromic, and neoplastic processes that require a broad and complex clinical approach for both medical and surgical treatment. Given their complexity and often multicompartment involvement, a multidisciplinary approach for diagnosis, patient and family counseling, and ultimately treatment provides the best patient satisfaction and clinical outcomes. Advances in minimally invasive surgical approaches, including endoscopic endonasal and transorbital approaches allows for more targeted surgical approaches through smaller corridors beyond more classic transcranial or transracial approaches...
March 23, 2024: Oral and Maxillofacial Surgery Clinics of North America
https://read.qxmd.com/read/38515557/treatment-of-cicatricial-lower-eyelid-ectropion-with-suture-of-horner-muscle-combined-with-fascia-transplantation
#11
JOURNAL ARTICLE
Kento Takaya, Shigeki Sakai, Kazuo Kishi
This case series aimed to describe a new technique for correcting contractures and deformities that reliably addresses lacrimal punctum deviation and severe cicatricial lower eyelid ectropion. This was a technical description and a retrospective interventional case series. Eyelid ectropion and lacrimal punctum deviation were treated surgically by grafting the fascia lata and suturing the tarsus-Horner muscle. In total, three patients underwent this surgery: one for burns, one for lower eyelid tumor resection, and the other for an orbital floor fracture following a motorcycle accident, all resulting in ectropion...
March 2024: Plastic and Reconstructive Surgery. Global Open
https://read.qxmd.com/read/38513708/reconstruction-of-orbital-exenteration-defects-with-cross-median-forehead-flaps
#12
JOURNAL ARTICLE
Sven H Baum, Mohammad Al-Bayati, Christopher Mohr, Roman Pförtner
The aim of this study was to examine the role of forehead flaps in the reconstruction of orbital defects after exenteration. Patients undergoing orbital exenteration and reconstruction using median forehead flaps from January 2002 to August 2019 were enrolled in this retrospective study. All the patients were evaluated for wound complications, functional results, and tumor relapse. In total, 105 patients completed the study. Twenty-nine complications in 24 of these patients were assessed. The most common complications were wound dehiscence (11%), partial necrosis of the flap (6%), and bleeding (4%)...
March 21, 2024: Facial Plastic Surgery: FPS
https://read.qxmd.com/read/38505973/nanoassemblies-of-heptamethine-cyanine-dye-initiated-poly-amino-acid-enhance-ros-generation-for-effective-antitumour-phototherapy
#13
JOURNAL ARTICLE
Pengwen Chen, Shangwei Li, Zhining Xu, Horacio Cabral
Phototherapy shows great potential for pinpoint tumour treatment. Heptamethine cyanine dyes like IR783 have high potential as agents for antitumour phototherapy due to their inherent tumour targeting ability, though their effectiveness in vivo is unsatisfactory for clinical translation. To overcome this limitation, we present an innovative strategy involving IR783-based polymeric nanoassemblies that improve the dye's performance as an antitumoural photosensitizer. In the formulation, IR783 is modified with cysteamine and used to initiate the ring-opening polymerization (ROP) of the N -carboxyanhydride of benzyl-L-aspartate (BLA), resulting in IR783-installed poly(BLA)...
March 20, 2024: Nanoscale Horizons: the Home for Rapid Reports of Exceptional Significance in Nanoscience and Nanotechnolgy
https://read.qxmd.com/read/38504671/maxillary-ameloblastoma-with-local-recurrence-orbital-invasion-and-systemic-metastases-a-case-report-and-review-of-the-literature
#14
Taylor J Linaburg, Javiera Araya, César A Briceño
INTRODUCTION: Maxillary ameloblastoma is a rare, slow-growing odontogenic tumor that can recur after surgical excision, be locally aggressive, and rarely develop systemic metastases. We describe the course and management of a patient with recurrent maxillary ameloblastoma with orbital invasion and systemic metastases, the fourth case of its kind to be described in the literature. CASE PRESENTATION: A 50-year-old female presented with left hyperglobus. A diagnosis of maxillary ameloblastoma was made based on biopsy and neuroimaging with MRI and CT...
2024: Case Reports in Ophthalmology
https://read.qxmd.com/read/38504646/new-onset-vision-impairment-in-children-magnetic-resonance-imaging-findings-by-age-groups
#15
JOURNAL ARTICLE
Esra Çıvgın, Semra Duran, Izzet Selçuk Parlak, Başak Gülleroğlu, İnci Elif Erbahçeci Timur, Özge Dedeoğlu, Ayşe Seçil Yücel Ekşioğlu
INTRODUCTION: Non-traumatic visual impairment is rare in the pediatric population, but early diagnosis and treatment of the cause is crucial to prevent long-term consequences affecting children's neurocognitive development. The authors aim to determine the most common causes of non-traumatic visual impairment in pediatric patients according to age groups by magnetic resonance imaging (MRI). METHODS: Images of patients who underwent contrast-enhanced cranial and orbital MRI for new-onset visual impairment between June 2019 and June 2022 were retrospectively reviewed...
March 20, 2024: Journal of Child Neurology
https://read.qxmd.com/read/38502351/gross-total-resection-in-optic-nerve-sheath-meningiomas-minimally-invasive-and-cosmetic-pleasing
#16
JOURNAL ARTICLE
Qin Dai, Xinyu Li, Yenan Fang, Bingyan Shen, Jinfei Wei, Qiqi Xie, Wencan Wu, Min Wang
PURPOSE: The optic nerve sheath meningioma (ONSM) is one of the most challenging tumors in orbital surgery. From the perspective of mental health and patient needs, we analyzed the necessity and importance of the endoscopic transnasal approach (ETA) combined with optic nerve transection (ONT) in gross-total resection (GTR) in ONSM patients with residual vision and aim to broaden the use of ONT for specific people. METHODS: The authors included patients with ONSMs who were treated between 2014 and 2022...
March 19, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38500295/neoadjuvant-chemotherapy-alone-or-combined-with-egfr-directed-targeted-therapy-or-anti-pd-1-immunotherapy-for-locally-advanced-lacrimal-sac-and-nasolacrimal-duct-carcinomas
#17
JOURNAL ARTICLE
Jeremy Goldfarb, Janet Fan, Luana Guimaraes de Sousa, Neal Akhave, Jeffrey Myers, Ryan Goepfert, Krish Manisundaram, Jiawei Zhao, Steven J Frank, Amy Moreno, Renata Ferrarotto, Bita Esmaeli
BACKGROUND/AIMS: We describe our findings in patients with locally advanced lacrimal sac and nasolacrimal duct (NLD) carcinoma who received neoadjuvant systemic therapy. METHODS: We identified patients with locally advanced primary lacrimal sac/NLD carcinoma treated with neoadjuvant systemic intravenous therapy at our institution during 2017-2019. RESULTS: The study included seven patients, four men and three women; the mean age was 60.4 years (range: 43-76)...
March 18, 2024: Seminars in Ophthalmology
https://read.qxmd.com/read/38497054/combining-surgery-radiotherapy-and-topical-chemotherapy-to-prevent-primary-orbital-exenteration-for-atypical-caruncular-melanoma-a-case-report
#18
Cédric De Landsheer, Valentien Merlevede, Celine Jacobs, Jo Van Dorpe, Julie De Zaeytijd, Virginie G S Ninclaus, Dimitri Roels
INTRODUCTION: This case report demonstrates the possibility of successful eye and vision-sparing therapy for caruncular melanoma. CASE PRESENTATION: We present an atypical presentation of a caruncular melanoma. After excisional biopsy, residual flat conjunctival melanosis resolved using topical chemotherapy (5-fluorouracil), which was well tolerated. Relapse of the melanoma was treated with external beam radiotherapy, but the tumor grew despite treatment. Eighteen months after complete excision of the relapsed melanoma, the patient remains tumor-free while the eye and its function remain preserved...
2024: Case Reports in Ophthalmology
https://read.qxmd.com/read/38492512/endoscopic-endonasal-approach-for-olfactory-groove-meningioma-resection-strategies-and-outcomes-in-a-retrospective-case-series
#19
JOURNAL ARTICLE
Amy J Wang, Christine K Lee, Max Blanch, Pratik A Talati, Stacey T Gray, Benjamin S Bleier, George A Scangas, Eric H Holbrook, William T Curry
OBJECTIVE: Though the endoscopic endonasal approach (EEA) is a widely accepted treatment for skull base tumors, the specific use of EEA for olfactory groove meningiomas (OGMs) is debated, with variable outcomes reported in the literature. We review the surgical results of OGM resections for one surgeon including the operative approach, surgical nuances, and outcomes, with a focus on factors relating to patient selection which favor EEA over transcranial approaches. METHODS: We retrospectively reviewed thirteen cases of endoscopic endonasal resection of olfactory groove meningiomas...
March 15, 2024: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://read.qxmd.com/read/38488786/superior-orbital-rim-grinding-as-a-novel-surgical-technique-to-approach-superior-and-posterior-orbital-tumors
#20
JOURNAL ARTICLE
Agustina L Mena, Constanza Mansur, Margarita Isa, Patricio Thompson, Rodolfo L Vigo
PURPOSE: To describe a novel surgical technique aimed to approach those orbital lesions located superior and posterior to the equator of the globe. METHODS: We describe a novel surgical technique that was performed in four patients to approach intraorbital tumors superiorly and posteriorly located. This technique was completed through an upper eyelid skin crease followed by grinding the superior orbital rim to achieve complete removal of the lesions. RESULTS: Complete removal of the lesion was accomplished in every case...
March 15, 2024: Orbit
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