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Orbital tumors

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https://www.readbyqxmd.com/read/29219959/primary-orbital-ewing-sarcoma-family-of-tumors-a-study-of-12-cases
#1
S Kaliki, S G Rathi, V A R Palkonda
PurposeThe purpose of this study is to discuss the clinical presentation, management, and outcomes of patients with primary orbital Ewing sarcoma family of tumors (ESFTs).Patients and methodsRetrospective study of 12 patients with biopsy-proven primary orbital ESFT.ResultsThe mean age at presentation of primary orbital ESFT was 12 years (median, 8 years; range, 5 months to 28 years). There were seven (58%) females and five (42%) males. The presenting complaints included proptosis (n=10; 83%) and swelling in the upper eyelid (n=2; 17%)...
December 8, 2017: Eye
https://www.readbyqxmd.com/read/29215408/18f-fdg-pet-ct-findings-of-mesenchymal-chondrosarcoma-of-the-orbit
#2
Mitsuteru Tsuchiya, Takayuki Masui, Yoshiro Otsuki, Harumi Sakahara
Mesenchymal chondrosarcoma of the orbit is an extremely rare and aggressive tumor. We report image findings of F-fluorodeoxyglucose (FDG) positron emission/computed tomography (PET/CT) in 2 cases, one primary case and one recurrent case. The F-FDG PET/CT images revealed high uptake with an SUVmax of 6.7 and 11.7, respectively. In both cases, the HEY1-CoA2 gene fusion was positive. The high uptake of F-FDG in mesenchymal chondrosarcoma of the orbit well suggests the malignancy of this tumor.
December 5, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29204171/magnetic-resonance-imaging-metal-artifact-reduction-for-eye-plaque-patient-with-dental-braces
#3
H Michael Gach, Stacie L Mackey, Sana Rehman, Mo Kadbi, Jacqueline E Zoberi, Jose Garcia-Ramirez, Perry W Grigsby
Purpose: To determine if metal artifact reduction can minimize magnetic susceptibility artifacts in the orbits for an eye plaque brachytherapy patient with metallic dental braces. Material and methods: A 62-year-old female patient with a choroidal melanoma in the right eye received a 1.5 T magnetic resonance imaging (MRI) simulation for 3D eye plaque brachytherapy planning. The protocol included conventional 3D T1-weighted and 2D T2-weighted MRIs. A vendor-supplied T2-weighted metal artifact reduction sequence was added to the protocol to reduce magnetic susceptibility artifacts from the metallic dental braces...
October 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29204167/interstitial-brachytherapy-for-orbital-soft-tissue-sarcoma-an-innovative-technique
#4
Siddhartha Laskar, Avinash Pilar, Nehal Khanna, Yogesh Ghadi
Purpose: To report an innovative technique of interstitial brachytherapy developed for treatment of orbital soft tissue tumors. Material and methods: A 4-month-old child diagnosed with rhabdomyosarcoma of orbit was treated with multiagent chemotherapy (CTh) and brachytherapy. Pre-planning computed tomography (CT) images were obtained and clinical target volume (CTV) was defined using the pre-treatment magnetic resonance imaging (MRI). Brachytherapy plan was generated for deciding optimal catheter placement...
October 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29147770/-infantile-hemangioma-of-the-eyelid
#5
F Lang, U P Press
Hemangiomas are one of the most common vascular tumors in infancy. In most cases no therapy is necessary and spontaneous regression is observed; however, if they arise in the periocular region, immediate action is required as rapid growth frequently leads to obstruction of the visual field with the risk of developing amblyopia and orbital suppression up to permanent disfigurement and stigmatization of those affected. Novel pharmaceutical treatment options led to a significant paradigm shift in the treatment of pediatric hemangiomas...
November 16, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29144839/distinguishing-benign-from-malignant-circumscribed-orbital-tumors-in-children
#6
Yufei Tu, Frederick A Jakobiec, Katherine Leung, Suzanne K Freitag
An orbital neoplasm in children is an uncommon clinical finding. Clinical suspicion should be based on many factors, including its location, the nature of onset, associated systemic signs and symptoms, family and social histories, examination findings, and radiographic characteristics. We present two cases of young children of similar age with a rapid-onset orbital mass. In both cases, a circumscribed round lesion was found in the superomedial orbit. An orbital schwannoma, a benign and usually slow growing tumor, was found in the first patient...
November 16, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/29135804/surgical-management-of-tumors-involving-meckel-s-cave-and-cavernous-sinus-role-of-an-extended-middle-fossa-and-lateral-sphenoidectomy-approach
#7
Daniel Q Sun, Arnold H Menezes, Matthew A Howard, Bruce J Gantz, David M Hasan, Marlan R Hansen
OBJECTIVE: To study the indications and outcomes of lateral sphenoidectomy as part of a combined skull base approach in the treatment of tumors involving Meckel's cave (MC) and cavernous sinus (CS). STUDY DESIGN: Retrospective patient series. SETTING: Tertiary referral center. PATIENTS: Twenty-two consecutive patients (mean age: 45 yr, range: 16-76) who underwent transzygomatic, extended middle fossa approaches for tumors involving MC and CS...
November 13, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29131914/pediatric-orbital-primitive-neuroectodermal-tumors
#8
Tayyab Afghani, Hassan Mansoor, Syed Naeem Raza Hamdani
PURPOSE: To present the clinical, radiological, histopathological, immunohistochemical features and the follow-up of orbital primitive neuroectodermal tumors (PNETs) in pediatric patients along with a review of the literature. METHODS: A retrospective analysis of all diagnosed cases of orbital PNET was done. Patients' ophthalmic findings, imaging, immunohistochemistry, metastatic work-up, treatment, globe salvation, and survival were documented and a mini literature review of orbital PNET was performed...
November 11, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29121219/clinicopathological-features-of-ocular-adnexal-mantle-cell-lymphoma-in-an-international-multicenter-cohort
#9
Marina K H Knudsen, Peter K Rasmussen, Sarah E Coupland, Bita Esmaeli, Paul T Finger, Gerardo F Graue, Hans E Grossniklaus, Jwu Jin Khong, Penny A McKelvie, Kaustubh Mulay, Elisabeth Ralfkiaer, Lene D Sjö, Geeta K Vemuganti, Bradley A Thuro, Jeremy Curtin, Steffen Heegaard
Importance: To our knowledge, the clinical features of ocular adnexal mantle-cell lymphoma (OA-MCL) have not previously been evaluated in a large multicenter cohort. Objective: To characterize the clinical features of OA-MCL. Design, Setting, and Participants: This retrospective multicenter study included patient data collected from January 1, 1980, through December 31, 2015, at 6 eye cancer centers in 4 countries. Medical records of 55 patients with OA-MCL were reviewed; the median length of follow-up was 33 months...
November 9, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29114305/frontal-mucocele-mimicking-a-frontal-subcutaneous-tumor
#10
Ellath Valappil Bijith, Shaju Mathew, Krishnaswamy Mahadevan
Mucoceles are chronic, expanding, mucosa lined pathology of the paranasal sinuses. Frontal mucocele usually presents with the visual complaints such as diplopia, diminution of vision, visual field defect, ptosis, orbital swelling, retro-orbital pain, displacement of eye globe, and proptosis. Very rarely, it can be present as a subcutaneous swelling. This article presents a 58-year-old male patient presenting with an asymptomatic periorbital swelling and a painless forehead mass of 3 years duration. There was a partial ptosis, and an elongated, soft, subcutaneous mass over the forehead...
October 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29101614/visual-outcome-after-endoscopic-third-ventriculostomy-for-hydrocephalus
#11
Ji-Ho Jung, Yong-Hyun Chai, Shin Jung, In-Young Kim, Woo-Youl Jang, Kyung-Sub Moon, Seul-Kee Kim, Sangjoon Chong, Seung-Ki Kim, Tae-Young Jung
PURPOSE: Hydrocephalus-related symptoms are mostly improved after successful endoscopic third ventriculostomy (ETV). However, visual symptoms can be different. This study was focused on visual symptoms. We analyzed the magnetic resonance images (MRI) of the orbit and visual outcomes. METHODS: From August 2006 to November 2016, 50 patients with hydrocephalus underwent ETV. The male-to-female ratio was 33:17, and the median age was 61 years (range, 5-74 years). There were 18 pediatric and 32 adult patients...
November 3, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29093739/aggressive-adenoid-cystic-carcinoma-of-maxillary-sinus-in-a-43-year-old-male-rare-case-report-and-review-of-literature
#12
Koorosh Rahmani, Shokouh Taghipour Zahir, Mohammad Baghi Yazdi, Alireza Navabazam
Adenoid cystic carcinoma (ACC) is a rare malignant tumor, mostly involving the minor salivary glands. Herein, we present a case of ACC in a 43-year-old man with symptoms of dental abscess as the initial presentation of the tumor. In spiral computed tomography (CT) scan, soft tissue mass with the erosion of maxillary sinus wall on the right side of the alveolar ridge was evident. Histopathological examination of the excised tumor with immunohistochemical studies (C-kit, Vimentin, pan-cytokeratin, p53, p63, and ki67 positive reaction) confirmed grade 2 ACC in the maxillary sinus...
2017: Case Reports in Medicine
https://www.readbyqxmd.com/read/29076466/-a-supraorbital-trans-eyebrow-approach-in-surgery-of-chiasmatic-sellar-and-anterior-cranial-fossa-tumors
#13
A G Alekseev, A A Pichugin, V I Danilov
OBJECTIVE: to analyze 31 resections of chiasmatic-sellar region (CSR) and anterior cranial fossa (ACF) tumors using the supraorbital trans-eyebrow approach (STA). MATERIAL AND METHODS: We analyzed medical histories of 31 patients who underwent tumor resection using STA in the period between October 2013 and April 2017. We analyzed the age and gender of patients, size and location of the tumor, presence of a neurological deficit, vision and olfactory functions before and after surgery, surgery duration, amount of intraoperative blood loss, rate of frontal sinus trephination and nasal liquorrhea, hemorrhagic and ischemic complications after surgery, Simpson grade of tumor resection, patient's condition before and after surgery (Glasgow Outcome Scale and Karnofsky Scale), and degree of patient satisfaction with the cosmetic result of surgery...
2017: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
https://www.readbyqxmd.com/read/29072521/orbital-fat-regeneration-following-hormonal-treatment-of-metastatic-breast-carcinoma
#14
Ramzi M Alameddine, Audrey C Ko, Masashi Mimura, Barbara A Parker, Jonathan H Lin, Bobby S Korn, Don O Kikkawa
Enophthalmos in the setting of breast cancer metastatic to the orbit results primarily from the disease pathogenesis, or secondary to treatment effects. Orbital volume restoration and fat regeneration following endocrine treatment monotherapy has not been previously reported. A 76- year-old previously healthy female presented with progressive right enophthalmos secondary to metastatic lobular breast carcinoma. Treatment with an aromatase inhibitor (letrozole) resulted in tumor regression and orbital fat restoration with a corresponding improvement in orbital volume and enophthalmos on clinical exam...
October 26, 2017: Orbit
https://www.readbyqxmd.com/read/29071276/small-choroidal-melanoma-revealed-by-a-large-extrascleral-extension
#15
Stéphanie Lemaître, Mathieu Zmuda, Pierre Vincent Jacomet, Christine Lévy-Gabriel, Rémi Dendale, Olivier Berges, Paul Fréneaux, Pascale Mariani, Laurence Desjardins, Olivier Galatoire, Nathalie Cassoux
AIMS: Orbital extraocular extension of choroidal melanoma is very rare with small melanomas. We report the case of a patient whose small choroidal melanoma was initially overlooked and was revealed by a large extrascleral extension. METHODS: A 48-year-old Caucasian woman presented with sudden total visual loss in the right eye. Multicolor imaging of the fundus showed right optic disc edema and an orange and green lesion near the optic disc. The diagnosis of unilateral optic neuritis was made...
September 2017: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/29061289/importance-of-neoadjuvant-chemotherapy-in-olfactory-neuroblastoma-treatment-series-report-and-literature-review
#16
Ricardo Bartel, Xavier Gonzalez-Compta, Enric Cisa, Francesc Cruellas, Alberto Torres, Aleix Rovira, Manel Manos
INTRODUCTION AND OBJECTIVES: Olfactory neuroblastoma (ONB) is a rare entity that constitutes less than 5% of nasosinusal malignancies. Mainstream treatment consists in surgical resection+/-adjuvant radiotherapy. By exposing results observed with apparition of new therapeutic options as neoadjuvant chemotherapy, the objective is to evaluate a series and a review of the current literature. METHODS: A retrospective review was conducted including patients diagnosed and followed-up for ONB from 2008 to 2015 in our institution...
October 20, 2017: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/29059312/conjunctival-melanoma-in-chinese-patients-local-recurrence-metastasis-mortality-and-comparisons-with-caucasian-patients
#17
COMPARATIVE STUDY
Chuandi Zhou, Yuxin Wang, Renbing Jia, Xianqun Fan
Purpose: To evaluate the prognosis in Chinese patients with conjunctival melanoma and determine its predictors. Further, to explore the racial differences in clinical characteristics and outcomes between Chinese and Caucasian patients. Methods: This cohort study included 57 eyes of 57 consecutive patients with pathologically verified conjunctival melanoma between 1996 and 2016. Medical records were reviewed for factors associated with the local recurrence, metastasis, and tumor-related mortality...
October 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29053040/intraconal-gauze-mass-an-unusual-complication-of-orbital-fracture-repair-a-case-report
#18
Fabiana Batista Caetano, Ana Filipa Duarte, Fernando Chahud, Murilo Bicudo Cintra, Antonio Augusto Velasco E Cruz
Gossypiboma and textiloma are terms used to describe tumor-like masses caused by retained gauze or surgical sponges after any operation. It is a rare surgical complication, usually difficult to diagnose due to its variable clinical presentation and nonstandard radiological appearance. We describe here a rare case of orbital gossypiboma in a child after surgical correction of an orbital blowout fracture.
October 20, 2017: Orbit
https://www.readbyqxmd.com/read/29049099/spontaneous-rupture-of-lacrimal-gland-pleomorphic-adenoma-pivotal-role-in-masquerading-orbital-cellulitis
#19
Farzad Pakdel, Niloofar Pirmarzdashti, Sasan Soltani, Zohreh Nozarian, Fahimeh Asadi Amoli, Abolfazl Kassaee
The authors aim to report a 68-year-old patient presenting with acute swelling and redness of orbital area diagnosed initially as orbital cellulitis. Surgical excision was decided based on clinical and imaging findings with the diagnosis of pleomorphic adenoma of the lacrimal gland. Lacrimal gland pleomorphic adenoma usually presents with painless gradual swelling of upper eyelid. In an exceptionally rare circumstance, this case showed acute orbital inflammation, and imaging findings of orbital inflammation mostly focused around the cystic space of the lacrimal gland tumor...
October 14, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29039986/orbital-exenteration-institutional-review-of-evolving-trends-in-indications-and-rehabilitation-techniques
#20
Hayyam Kiratli, İrem Koç
PURPOSE: To determine the changes in indications for orbital exenteration over 20 years and to assess its impact on patient survival. Evolving techniques of rehabilitation of the orbit in our institution were also evaluated. METHODS: This was a retrospective review of hospital records of patients who underwent orbital exenteration from 1995 to 2015 in a tertiary care center. Data extracted included primary location of the tumor, preoperative treatments, interval between initial diagnosis and exenteration, status of surgical margins, presence of metastatic disease, and postoperative survival...
October 17, 2017: Orbit
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