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Endometriosis laparoscopy

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https://www.readbyqxmd.com/read/28345488/deep-infiltrating-endometriosis-and-endometrial-adenocarcinoma-express-high-levels-of-myostatin-and-its-receptors-messenger-rnas
#1
Patrizia Carrarelli, Lucia Funghi, Pasquapina Ciarmela, Gabriele Centini, Fernando M Reis, Cynthia Dela Cruz, Alberto Mattei, Silvia Vannuccini, Felice Petraglia
Myostatin is a growth factor member of the transforming growth factor β superfamily, which is known to play major roles in cell proliferation and differentiation. The present study investigated the messenger RNA (mRNA) expression of myostatin and myostatin receptors (activin receptor-like kinase 4 [ALK4], transforming growth factor (TGF)-β type I receptor kinase [ALK5] and activin receptor type IIB [ActRIIB]) in endometrium of healthy women during menstrual cycle as well as in benign (endometriosis, polyps) and malignant (endometrial adenocarcinoma) conditions...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28342392/value-of-the-68-ga-dotatate-pet-ct-in-the-diagnosis-of-endometriosis-a-pilot-study
#2
M Fastrez, C Artigas, N Sirtaine, Z Wimana, M Caillet, S Rozenberg, P Flamen
OBJECTIVE: The non-invasive diagnosis of endometriosis remains challenging. Recent data suggested that somatostatin might be involved in its pathogenesis. High sensitive visualization of somatostatin receptors expression is possible using PET-CT imaging after the administration of a (68)Ga-labeled somatostatin analog (DOTATATE) that will bind to the somatostatin receptor sub-types 2 and 5. The aim of the present study was to assess the usefulness of (68)Ga-DOTATATE PET-CT in the diagnosis of endometriosis...
March 16, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28333337/tubal-anastomosis-after-previous-sterilization-a-systematic-review
#3
Jacoba A H van Seeters, Su Jen Chua, Ben W J Mol, Carolien A M Koks
BACKGROUND: Female sterilization is one of the most common contraceptive methods. A small number of women, however, opt for reversal of sterilization procedures after they experience regret. Procedures can be performed by laparotomy or laparoscopy, with or without robotic assistance. Another commonly utilized alternative is IVF. The choice between surgery and IVF is often influenced by reimbursement politics for that particular geographic location. OBJECTIVE AND RATIONALE: We evaluated the fertility outcomes of different surgical methods available for the reversal of female sterilization, compared these to IVF and assessed the prognostic factors for success...
February 22, 2017: Human Reproduction Update
https://www.readbyqxmd.com/read/28333221/surgical-treatment-of-adhesion-related-chronic-abdominal-and-pelvic-pain-after-gynaecological-and-general-surgery-a-systematic-review-and-meta-analysis
#4
Barend A van den Beukel, Roy de Ree, Suzanne van Leuven, Erica A Bakkum, Chema Strik, Harry van Goor, Richard P G Ten Broek
BACKGROUND: Chronic pain is a frequent post-operative complication, affecting ~20-40% of patients who have undergone surgery of the female genital or alimentary tract. Chronic pain is an important risk factor for diminished quality of life after surgery. Adhesions are frequently associated with chronic post-operative pain; however, surgical treatment of adhesion-related pain is controversial. OBJECTIVE AND RATIONALE: The aim of this study was to investigate the efficacy and harms of surgical interventions for chronic post-operative pain attributable to adhesions...
March 2, 2017: Human Reproduction Update
https://www.readbyqxmd.com/read/28333208/soluble-vcam-1-soluble-icam-1-ratio-is-a-promising-biomarker-for-diagnosing-endometriosis
#5
L Kuessel, R Wenzl, K Proestling, S Balendran, P Pateisky, Yotova, G Yerlikaya, B Streubel, H Husslein
STUDY QUESTION: Do cell adhesion molecules play a role in endometriosis, and can they be used as a biomarker for diagnosing endometriosis? SUMMARY ANSWER: Altered expression of vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1) in the endometrium and peritoneum may play a key role in endometriosis and the soluble VCAM-1/soluble ICAM-1 ratio is a promising biomarker. WHAT IS KNOWN ALREADY: Cell adhesion molecules are cell surface proteins that mediate cellular adherence, inflammatory and immune responses, and cancer-related biological processes...
February 23, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28290209/plasma-brain-derived-neurotrophic-factor-in-women-with-pelvic-pain-a-potential-biomarker-for-endometriosis
#6
Ana L Rocha, Erica L Vieira, Márcia C Ferreira, Laura M Maia, Antonio L Teixeira, Fernando M Reis
AIM: To test whether plasma BDNF levels are useful to predict the presence of endometriosis in women with pelvic pain. PATIENTS & METHODS: Prospective cross-sectional study including 67 consecutive women aged 24-49 years, scheduled for laparoscopy due to chronic pelvic pain. Preoperative plasma samples were assayed for BDNF using a commercial enzyme immunoassay. RESULTS: Women with ovarian endometrioma had higher preoperative plasma BDNF (1063 ± 157 pg/ml) compared with women with other benign ovarian tumors (537 ± 131 pg/ml, F = 2...
March 14, 2017: Biomarkers in Medicine
https://www.readbyqxmd.com/read/28288013/new-developments-in-surgery-for-endometriosis-and-pelvic-pain
#7
Thanh Ha Luu, M Jean Uy-Kroh
Endometriosis is a common disease affecting reproductive age women. Pain is one of the most common symptoms associated with endometriosis. When medical therapy has failed or in known deeply infiltrating endometriosis, surgical management is warranted. Laparoscopy is the gold standard for diagnosis and treatment of endometriosis. Recent developments in surgery have shown the feasibility of robotic surgery for endometriosis, although these methods have not been shown to be superior to conventional laparoscopy...
March 10, 2017: Clinical Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28271700/the-actual-role-of-robotics-in-the-management-of-endometriosis
#8
Vito Cela, Maria E Obino, Claudia Sergiampietri, Giovanna Simi, Francesca Papini, Sara Pinelli, Letizia Freschi, Paolo G Artini
The advent of robot-assisted laparoscopy (RAL) represents an important innovation and has opened new perspectives for treatment of endometriosis, in particular in deep infiltrating endometriosis (DIE). RAL could offer several technical advantages in treating this complex disease, such as 3D vision, tremor filtration and better surgical ergonomy, would be able to improve surgical performances without increasing in surgical time, blood loss, intra- and postoperative complications and it reduces the rates of conversion to laparotomy...
March 7, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28270880/colonic-endometriosis-dig-deeper-for-diagnosis
#9
Kanthi Rekha Badipatla, Anisha Vupputuri, Masooma Niazi, Marie-Nirva Blaise, Suresh Kumar Nayudu
Endometriosis is a common gynecological condition wherein there is an ectopic implantation of the uterine endometrial tissue. While several diagnostic modalities are described for the condition, laparoscopy remains the gold standard. There is still an undiscovered area to diagnose colonic endometriosis at an earlier stage. We present a case report of a reproductive age woman with cyclical rectal bleeding diagnosed with colonic endometriosis with colonoscopy and biopsy using saline injection lift and sampling technique...
February 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28263049/is-there-a-role-of-single-port-laparoscopy-in-the-treatment-of-endometriosis
#10
Angelos Daniilidis, Kimon Chatzistamatiou, Efstratios Assimakopoulos
BACKGROUND: Endometriosis is among the most common benign gynecological conditions, and it affects 6-15% of women of reproductive. During recent decades, minimally invasive surgical techniques, and especially laparoscopy, have gained significant ground concerning the treatment of gynecological disorders. To date, laparoscopy is considered the gold standard for the diagnosis and treatment of endometriosis. METHODS: Available papers in Pub Med and Scopus data base, written in English language have been used for the current narrative review...
March 6, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28254679/laparoscopic-uterovaginal-anastomosis-for-congenital-isolated-cervical-agenesis-a-case-report
#11
G Scibilia, B Pecorino, I Pagano, P Scollo
Management of cervical agenesis is a challenge owing to the complexity of the malformation and the difficulty in restoring and preserving fertility. We propose a minimally invasive fertility-sparing surgery for a 17-year-old woman with congenital cervical agenesis and normal vagina and uterus confirmed by vaginoscopy. The patient was admitted for primary amenorrhea, haematometra, and cyclic pelvic pain. She had previous laparoscopies for ovarian endometriosis. Our surgical approach involved the creation of isthmus-vaginal anastomosis with utero-vaginal reconnection...
February 22, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28254227/unexpected-epithelial-ovarian-cancers-arising-from-presumed-endometrioma-a-10-year-retrospective-analysis
#12
Hsin-Hong Kuo, Chen-Ying Huang, Shir-Hwa Ueng, Kuan-Gen Huang, Chyi-Long Lee, Chih-Feng Yen
OBJECTIVE: To evaluate the incidence and prognosis of unexpected epithelial ovarian cancers (EOCs) occurring in presumed benign endometrioma. MATERIALS AND METHODS: Patients who underwent primary surgery at Chang Gung Memorial Hospital between November 2003 and October 2013 were searched with the Systematized Nomenclature of Medicine code followed by chart review. RESULTS: The incidence of unexpected EOCs in presumed ovarian endometrioma was 0...
February 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28238489/laparoscopy-vs-robotic-surgery-for-endometriosis-larose-a-multicenter-randomized-controlled-trial
#13
Enrique Soto, Thanh Ha Luu, Xiaobo Liu, Javier F Magrina, Megan N Wasson, Jon I Einarsson, Sarah L Cohen, Tommaso Falcone
OBJECTIVE: To determine whether the use of the robot for surgical treatment of endometriosis is better than traditional laparoscopy in terms of operative length, perioperative parameters, and quality of life outcomes. DESIGN: Multicenter, randomized clinical trial. SETTING: University teaching hospitals. PATIENT(S): Women aged >18 years with suspected endometriosis who elected to undergo surgical management. INTERVENTION(S): Randomization to conventional or robot-assisted laparoscopic removal of endometriosis...
February 23, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28216913/female-sexual-dysfunction-in-patients-with-endometriosis-indian-scenario
#14
Vineet V Mishra, Sakshi Nanda, Khushali Gandhi, Rohina Aggarwal, Sumesh Choudhary, Raveendra Gondhali
BACKGROUND: Female sexual dysfunction (FSD) in Indian women is often overlooked due to cultural beliefs and considered as social taboos. Sexuality is an important and integral part of life. There are many causes of sexual dysfunction, but the prevalence of FSD in endometriotic patients is still underdiagnosed. MATERIALS AND METHODS: Study design - Cross-sectional observational study conducted at tertiary care center, from June 2015 to March 2016. Sample size - Fifty-one patients in reproductive age group (18-47 years) who were diagnosed with endometriosis on diagnostic laparoscopy were included...
October 2016: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/28194637/robotic-assisted-laparoscopy-in-reproductive-surgery-a-contemporary-review
#15
REVIEW
Jayapriya Jayakumaran, Sejal D Patel, Bhushan K Gangrade, Deepa Maheswari Narasimhulu, Soundarya Ramanatha Pandian, Celso Silva
Robotic surgery is a conceptual fusion of the conventional open surgery and the minimally invasive laparoscopic surgery. We reviewed the current role of robotic-assisted laparoscopy in the field of reproductive surgery by a literature search in PubMed database. We analyzed the reported advantages and limitations of the use of robotics in reproductive surgeries like myomectomy, tubal reanastomosis, endometriosis, ovarian tissue cryopreservation, and ovarian transposition. Overall, robotic assistance in reproductive surgery resulted in decreased blood loss, less post-operative pain, shorter hospital stay, and faster convalescence, whereas reproductive outcomes were similar to open/laparoscopic approaches...
February 14, 2017: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/28174513/cervical-mucus-proteome-in-endometriosis
#16
Giuseppe Grande, Federica Vincenzoni, Domenico Milardi, Giuseppina Pompa, Domenico Ricciardi, Erika Fruscella, Francesca Mancini, Alfredo Pontecorvi, Massimo Castagnola, Riccardo Marana
BACKGROUND: Endometriosis is a chronic gynecological inflammatory disease characterized by the presence of functional endometrial glands and stroma outside of the uterine cavity. It affects 7-10% of women of reproductive age and up to 50% of women with infertility. The current gold standard for the diagnosis combines laparoscopic evaluation and biopsy of the visualized lesions. However, laparoscopy requires general anesthesia and developed surgical skills and it has a high procedural cost...
2017: Clinical Proteomics
https://www.readbyqxmd.com/read/28124530/cystoscopy-assisted-laparoscopy-for-bladder-endometriosis-modified-light-to-light-technique-for-bladder-preservation
#17
Rafael Mamprin Stopiglia, Ubirajara Ferreira, Daniel Gustavo Faundes, Carlos Alberto Petta
INTRODUCTION: Endometriosis is a disease with causes still unclear, affecting approximately 15% of women of reproductive age, and in 1%-2% of whom it may involve the urinary tract. The bladder is the organ most frequently affected by endometriosis, observed around 85% of the cases. In such cases, the most effective treatment is partial cystectomy, especially via videolaparoscopy. Study Objective, Design, Size and Duration: In order to identify and delimit the extent of the intravesical endometriosis lesion, to determine the resection limits, as well as to perform an optimal reconstruction of the organ aiming for its maximum preservation, we performed a cystoscopy simultaneously with the surgery, employing a modified light-tolight technique in 25 consecutive patients, from September 2006 to May 2012...
January 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28093048/myofibroblasts-are-evidence-of-chronic-tissue-microtrauma-at-the-endometrial-myometrial-junctional-zone-in-uteri-with-adenomyosis
#18
Mohamed Gamal Ibrahim, Martin Sillem, Johanna Plendl, Vito Chiantera, Jalid Sehouli, Sylvia Mechsner
BACKGROUND: Adenomyosis (AM) uteri exhibit hyperperistalsis. The latter causes a chronic tissue trauma at the endometrial-myometrial junctional zone (EMJZ). Upon tissue trauma, microdehiscences in the myometrium facilitate the translocation of basal endometrial fragments into the myometrium. There, a metaplasia (mediated by transforming growth factor β1 [TGFβ1] and connective tissue growth factor [CTGF]) occurs and AM lesions develop. The abundance of myofibroblasts in a tissue hallmarks metaplasia and points to a tissue microtrauma...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28069481/thoracic-endometriosis-syndrome-association-with-pelvic-endometriosis-and-fertility-status
#19
Jessica Ottolina, Francesca De Stefano, Paola Viganò, Paola Ciriaco, Piero Zannini, Massimo Candiani
STUDY OBJECTIVE: To evaluate associations among catamenial pneumothorax, pelvic endometriosis, and fertility status. DESIGN: Retrospective study (Canadian Task Force classification II-2). SETTING: Departments of Thoracic Surgery and Obstetrics and Gynecology, San Raffaele Hospital, Milan, Italy. PATIENTS: Sixteen females referred to the Department of Thoracic Surgery for treatment of spontaneous pneumothorax between January 2001 and January 2014 and referred to the outpatient clinic for gynecologic follow-up...
March 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28042542/oxidative-stress-statues-in-serum-and-follicular-fluid-of-women-with-endometriosis
#20
Nahid Nasiri, Ashraf Moini, Poopak Eftekhari-Yazdi, Leila Karimian, Reza Salman-Yazdi, Arezoo Arabipoor
OBJECTIVE: This study aimed to evaluate the levels of two oxidative stress (OS) markers including lipid peroxide (LPO) and total antioxidant capacity (TAC) in both serum and follicular fluid (FF) of women with endometriosis after puncture. MATERIALS AND METHODS: In this cross-sectional study, a total number of sixty-three women younger than 40 years old with laparoscopy (gold standard for endometriosis diagnosis) indication underwent in vitro fertilization (IVF) program in the Royan Institute, Tehran, Iran from September 2013 to October 2014...
2017: Cell Journal
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