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Endometriosis laparoscopy

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https://www.readbyqxmd.com/read/29628331/prediction-of-endometriosis-fertility-index-in-patients-with-endometriosis-associated-infertility-after-laparoscopic-treatment
#1
Xianghui Zhang, Dong Liu, Wei Huang, Qiushi Wang, Xue Feng, Jing Tan
The effect of endometriosis on fecundity is unclear. Although surgery plays a vital role in the treatment of related infertility, pregnancy outcomes after laparoscopy are poorly correlated with the currently used staging system. To address this, the Endometriosis Fertility Index (EFI) was developed. This retrospective study was designed to assess the predictive value of the EFI for patients with endometriosis-associated infertility. A total of 1325 patients with endometriosis-associated infertility were eligible for inclusion, 1097 of whom were successfully interviewed and 228 lost to follow-up (17...
March 27, 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29621955/the-hyaluronic-acid-system-is-intact-in-menstrual-endometrial-cells-in-women-with-and-without-endometriosis
#2
Jennifer F Knudtson, Jessica E McLaughlin, Marlen Tellez Santos, Peter A Binkley, Rajeshwar R Tekmal, Robert S Schenken
OBJECTIVE: To characterize the production and degradation of hyaluronic acid (HA) in menstrual endometrial epithelial cells (EECs) and endometrial stromal cells (ESCs) in women with and without endometriosis. To identify the presence of CD44, the primary receptor of HA, in menstrual EECs and ESCs in women with and without endometriosis. DESIGN: In vitro study. SETTING: Academic center. PATIENT(S): Deidentified patient samples from women with and without endometriosis...
January 1, 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29609032/surgical-excision-versus-ablation-for-superficial-endometriosis-associated-pain-a-randomized-controlled-trial
#3
Kristin Riley, Andrea Benton, Timothy A Deimling, Allen R Kunselman, Gerald J Harkins
STUDY OBJECTIVE: To compare surgical excision and ablation of endometriosis for treatment of chronic pelvic pain. DESIGN: Canadian task force Category I - randomized clinical trial with 12-month follow-up. SETTING: Single academic tertiary care hospital. PATIENTS: Women with minimal to mild endometriosis undergoing laparoscopy. INTERVENTIONS: Excision or ablation of superficial endometriosis at the time of robot-assisted laparoscopy...
March 30, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29587611/serum-microrna-biomarkers-regulated-by-simvastatin-in-a-primate-model-of-ems
#4
Emine Cosar, Ramanaiah Mamillapalli, Irene Moridi, Antoni Duleba, Hugh S Taylor
Endometriosis (EMS) is a chronic inflammatory and estrogen-dependent disease that causes pain and infertility in reproductive-aged women. Due to the delay in diagnosis, there is a pressing need for accurate biomarkers. Detection of serum noncoding RNA molecules such as microRNAs (miRNAs) shows promise as a noninvasive diagnostic strategy; we previously identified miRNAs that are highly sensitive and specific biomarkers for the disease. In this study, we investigate the expression of these miRNAs in a nonhuman primate model of EMS...
January 1, 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29573627/intraoperative-enhanced-imaging-for-detection-of-endometriosis-a-systematic-review-of-the-literature
#5
REVIEW
Mahdi Al-Taher, Shugi Hsien, Rutger M Schols, Nehalennia Van Hanegem, Nicole D Bouvy, Gerard A J Dunselman, Laurents P S Stassen
The diagnosis of peritoneal endometriosis during laparoscopy may be difficult due to the polymorphic aspects of the lesions. Enhanced imaging using contrast agents has potential to provide a better identification of peritoneal endometriosis. The aim of this systematic review is to provide an overview of the literature on what is known about the intraoperative laparoscopic visual enhancement of peritoneal endometriosis using contrast agents. A systematic review was done of studies about enhanced imaging during laparoscopy for endometriosis using contrast agents...
March 15, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29564318/postoperative-outcomes-of-natural-orifice-transluminal-endoscopic-surgery-assisted-vaginal-hysterectomy-and-conventional-laparoscopic-assisted-vaginal-hysterectomy-a-comparative-study
#6
Seong Hee Kim, Chan Hee Jin, In Taek Hwang, Jun Sook Park, Jung Hwan Shin, Dae Woon Kim, Yong Soo Seo, Jee Nah Sohn, Yun Seok Yang
Objective: The present study aimed to determine the differences in outcomes between natural orifice transluminal endoscopic surgery-assisted vaginal hysterectomy (NAVH) and conventional laparoscopy-assisted vaginal hysterectomy (LAVH). Methods: We retrospectively reviewed the charts of patients who between July 2012 and September 2015, were diagnosed as having benign uterine disease such as uterine myoma, endometriosis, or adenomyosis and managed via NAVH or LAVH in a single-center (Eulji University Hospital)...
March 2018: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/29551300/-first-line-management-without-ivf-of-infertility-related-to-endometriosis-result-of-medical-therapy-results-of-ovarian-superovulation-results-of-intrauterine-insemination-cngof-has-endometriosis-guidelines
#7
J Boujenah, P Santulli, E Mathieu-d'Argent, C Decanter, C Chauffour, P Poncelet
INTRODUCTION: Using the structured methodology of French guidelines (HAS-CNGOF), the aim of this chapter was to formulate good practice points (GPP), in relation to optimal non-ART management of endometriosis related to infertility, based on the best available evidence in the literature. MATERIALS AND METHODS: This guideline was produced by a group of experts in the field including a thorough systematic search of the literature (from January 1980 to March 2017)...
March 15, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29548642/a-focus-on-the-distinctions-and-current-evidence-of-endometriosis-in-adolescents
#8
REVIEW
Vincenzo de Sanctis, Michail Matalliotakis, Ashraf T Soliman, Heba Elsefdy, Salvatore Di Maio, Bernadette Fiscina
Endometriosis (EM) occurring in adolescents presents distinct clinical and histologic characteristics compared to the disease in women. Because the symptoms of EM are nonspecific, often overlapping with those experienced in a range of gynecological and gastrointestinal conditions, the process of reaching a diagnosis of EM is often delayed. The diagnosis of EM is suspected depending on the history and the symptoms and signs, is corroborated by physical examination and imaging techniques, and is finally proved by histological examination of specimens collected during laparoscopy...
February 19, 2018: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29548620/-epidemiology-and-diagnosis-strategy-cngof-has-endometriosis-guidelines
#9
A Fauconnier, B Borghese, C Huchon, I Thomassin-Naggara, C-A Philip, T Gauthier, N Bourdel, A Denouel, A Torre, P Collinet, M Canis, X Fritel
Based on the best evidence available, we have provided guidelines for clinical practice to target the nature of endometriosis as a disease, the consequences of its natural history on management, and the clinical and imaging evaluation of the disease according to the level of care (primary care, specialized or referral). The frequency of endometriosis is unknown in the general population; endometriosis requires management when it causes symptoms (pain, infertility) or when it affect the function of an organ...
March 13, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29534879/-surgical-management-of-deep-endometriosis-with-colorectal-involvement-cngof-has-endometriosis-guidelines
#10
M Ballester, H Roman
Deep endometriosis with colorectal involvement is considered one of the most severe forms of the disease due to its impact on patients' quality of life and fertility but also by the difficulties encountered by the clinicians when proposing a therapeutic strategy. Although the literature is very rich, evidence based medicine remains poor explaining the great heterogeneity concerning the management of such patients. Surgery therefore remains a therapeutic option. It improves the intensity of gynecological, digestive and general symptoms and the quality of life...
March 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29530560/-diagnosis-accuracy-of-endoscopy-laparoscopy-hysteroscopy-fertiloscopy-cystoscopy-colonoscopy-in-case-of-endometriosis-cngof-has-endometriosis-guidelines
#11
A Tardieu, F Sire, T Gauthier
OBJECTIVE: To provide clinical practice guidelines from the French college of obstetrics and gynecology (CNGOF) with the Haute Autorité de santé (HAS), based on the best evidence available, concerning the diagnosis accuracy of endoscopy (laparoscopy, hysteroscopy, fertiloscopy, cystoscopy, colonoscopy) in case of endometriosis. MATERIAL AND METHODS: English and French review of literature about the diagnosis accuracy of endoscopy in case of endometriosis. RESULTS AND CONCLUSION: Laparoscopy is useful in case of suspected endometriosis in patients with symptoms or infertility when appropriate preoperative assessment is negative (grade C)...
March 9, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29530553/-extragenital-endometriosis-parietal-thoracic-diaphragmatic-and-nervous-lesions-cngof-has-endometriosis-guidelines
#12
B Merlot, S Ploteau, A Abergel, C Rubob, C Hocke, M Canis, X Fritel, H Roman, P Collinet
According to some studies, extragenital endometriosis represents 5% of the localisations. Its prevalence seems to be underestimated. The extra pelvic localisation can make the diagnosis more difficult. Nevertheless, the recurrent and catamenial symptomatology can evoke this pathology. Surgery seems to be the unique efficient treatment for parietal lesions. Pain linked to nervous lesions (peripheric and sacral roots) seems to be underestimated and difficult to diagnose because of various localisations. Neurolysis seems to have encouraging results...
March 9, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29524590/evaluation-validation-and-refinement-of-noninvasive-diagnostic-biomarkers-for-endometriosis-endomarker-a-protocol-to-phenotype-bio-specimens-for-discovery-and-validation
#13
Kurt Barnhart, Linda Giudice, Steve Young, Tracey Thomas, Michael P Diamond, James Segars, Wahid A Youssef, Stephen Krawetz, Nanette Santoro, Esther Eisenberg, Heping Zhang
OBJECTIVE: Endometriosis is a chronic, estrogen dependent condition that affects 5-10% of reproductive aged women and is associated with pelvic pain and infertility. As the approach to therapy shifts from surgical ablation to pharmacological control, a non-surgical mode of diagnosis would be desirable. The ENDOmarker study was designed by the NICHD Reproductive Medicine Network (RMN) to obtain well characterized and phenotyped bio specimens in a standardized fashion from women with and without endometriosis...
March 7, 2018: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29523392/endometriosis-endometrioma-and-art-results-current-understanding-and-recommended-practices
#14
REVIEW
Federico Prefumo, A Cristina Rossi
Endometriosis and infertility are linked in a complex relationship, and a number of different pathogenetic mechanisms may associate the two. Endometriosis is diagnosed in 6-8% of women undergoing ART. Women with endometriosis appear to have similar ART outcomes compared to controls in terms of live birth rates, despite a lower oocyte quality. Laparoscopy should not be routinely performed before ART with the only aim to diagnose mild or moderate endometriosis, but if the latter is found, surgical removal can be considered, as it might improve pregnancy rates...
February 15, 2018: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29510965/-minimal-and-mild-endometriosis-impact-of-the-laparoscopic-surgery-on-pelvic-pain-and-fertility-cngof-has-endometriosis-guidelines
#15
S Ploteau, B Merlot, H Roman, M Canis, P Collinet, X Fritel
Minimal and mild endometriosis (stage 1 and 2 AFSR) can lead to chronic pelvic pain and infertility but can also exist in asymptomatic patients. The prevalence of asymptomatic patients with minimal and mild endometriosis is not clear but typical endometriosis lesions are found in about 5 to 10% of asymptomatic women and more than 50% of painful and/or infertile women. Laparoscopic treatment of minimal and mild endometriotic lesions is justified in case of pelvic pain because their destruction decrease significatively the pain compared with diagnostic laparoscopy alone...
March 3, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29492476/does-laparoscopy-still-has-a-role-in-modern-fertility-practice
#16
Ahmad Mahran, Ahmed R Abdelraheim, Abdelrahman Eissa, Mohamed Gadelrab
Background: More than 3 decades after the introduction of in vitro fertilization (IVF) and despite the improved success rates of assisted reproductive technologies, the argument for performing laparoscopy as a part of the infertility workup still stands. Objective: To evaluate the role of laparoscopy±hysteroscopy in diagnosis and management of infertility in our setting in view of modern fertility practice. Materials and Methods: This case control study was carried out on 600 infertile women subjected to laparoscopy or combined laparoscopy and hysteroscopy at endoscopy unit in Minia University Hospital, Egypt during the period from January 2012 to December 2014...
December 2017: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/29465552/diagnostic-accuracy-of-magnetic-resonance-imaging-transvaginal-and-transrectal-ultrasonography-in-deep-infiltrating-endometriosis
#17
Saeed Alborzi, Alireza Rasekhi, Zahra Shomali, Gooya Madadi, Mahshid Alborzi, Mahboobeh Kazemi, Azam Hosseini Nohandani
To determine the diagnostic accuracy of pelvic magnetic resonance imaging (MRI), transvaginal sonography (TVS), and transrectal sonography (TRS) in diagnosis of deep infiltrating endometriosis (DIE).This diagnostic accuracy study was conducted during a 2-year period including a total number of 317 patients with signs and symptoms of endometriosis. All the patients were evaluated by pelvic MRI, TVS, and TRS in the same center. The criterion standard was considered to be the laparoscopy and histopathologic examination...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29463003/the-mirna-mirage-how-close-are-we-to-finding-a-non-invasive-diagnostic-biomarker-in-endometriosis-a-systematic-review
#18
REVIEW
Swati Agrawal, Thomas Tapmeier, Nilufer Rahmioglu, Shona Kirtley, Krina Zondervan, Christian Becker
BACKGROUND: Endometriosis is a common disorder of the reproductive age group, characterised by the presence of ectopic endometrial tissue. The disease not only causes enormous suffering to the affected women, but also brings a tremendous medical and economic burden to bear on society. There is a long lag phase between the onset and diagnosis of the disease, mainly due to its non-specific symptoms and the lack of a non-invasive test. Endometriosis can only be diagnosed invasively by laparoscopy...
February 17, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29462326/secreted-frizzled-related-protein-2-sfrp2-expression-promotes-lesion-proliferation-via-canonical-wnt-signaling-and-indicates-lesion-borders-in-extraovarian-endometriosis
#19
T Heinosalo, M Gabriel, L Kallio, P Adhikari, K Huhtinen, T D Laajala, E Kaikkonen, A Mehmood, P Suvitie, H Kujari, T Aittokallio, A Perheentupa, M Poutanen
STUDY QUESTION: What is the role of SFRP2 in endometriosis? SUMMARY ANSWER: SFRP2 acts as a canonical WNT/CTNNB1 signaling agonist in endometriosis, regulating endometriosis lesion growth and indicating endometriosis lesion borders together with CTNNB1 (also known as beta catenin). WHAT IS KNOWN ALREADY: Endometriosis is a common, chronic disease that affects women of reproductive age, causing pain and infertility, and has significant economic impact on national health systems...
February 15, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29455621/optimization-of-endometrial-decidualization-in-the-menstruating-mouse-model-for-preclinical-endometriosis-research
#20
Daniëlle Peterse, Katrien De Clercq, Chloë Goossens, M Mercedes Binda, F O Dorien, Philippa Saunders, Joris Vriens, Amelie Fassbender, Thomas M D'Hooghe
BACKGROUND: To induce endometrial decidualization in rodents, an intrauterine oil stimulus can be delivered via the nontraumatic vagina or via the traumatic laparotomy. However, there is considerable variation in amount of decidualization using these inducing methods. Therefore, we studied which oil delivery route could achieve the highest rate of endometrial decidualization along the full length of both uterine horns. METHODS: To induce decidualization, ovariectomized C57Bl/6J mice were injected with estrogen (100 ng/day; 3 days)...
January 1, 2018: Reproductive Sciences
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