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Endometriosis laparoscopy

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https://www.readbyqxmd.com/read/28093048/myofibroblasts-are-evidence-of-chronic-tissue-microtrauma-at-the-endometrial-myometrial-junctional-zone-in-uteri-with-adenomyosis
#1
Mohamed Gamal Ibrahim, Martin Sillem, Johanna Plendl, Vito Chiantera, Jalid Sehouli, Sylvia Mechsner
BACKGROUND: Adenomyosis (AM) uteri exhibit hyperperistalsis. The latter causes a chronic tissue trauma at the endometrial-myometrial junctional zone (EMJZ). Upon tissue trauma, microdehiscences in the myometrium facilitate the translocation of basal endometrial fragments into the myometrium. There, a metaplasia (mediated by transforming growth factor β1 [TGFβ1] and connective tissue growth factor [CTGF]) occurs and AM lesions develop. The abundance of myofibroblasts in a tissue hallmarks metaplasia and points to a tissue microtrauma...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28069481/thoracic-endometriosis-syndrome-association-with-pelvic-endometriosis-and-fertility-status
#2
Jessica Ottolina, Francesca De Stefano, Paola Viganò, Paola Ciriaco, Piero Zannini, Massimo Candiani
STUDY OBJECTIVE: Thoracic endometriosis syndrome (TES), characterized mainly by catamenial pneumothorax, represents a relevant condition in patients affected by endometriosis. However, few studies have analyzed this condition under the gynecological point of view, in terms of characteristic of endometriosis and fertility status of affected women. In our study, we evaluate the association between catamenial pneumothorax, pelvic endometriosis and the fertility status of the patients. DESIGN: Retrospective study of 16 patients treated for catamenial pneumothorax between January 2001 and January 2014 at the Thoracic Surgery Department of San Raffaele Scientific Institute...
January 6, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28042542/oxidative-stress-statues-in-serum-and-follicular-fluid-of-women-with-endometriosis
#3
Nahid Nasiri, Ashraf Moini, Poopak Eftekhari-Yazdi, Leila Karimian, Reza Salman-Yazdi, Arezoo Arabipoor
OBJECTIVE: This study aimed to evaluate the levels of two oxidative stress (OS) markers including lipid peroxide (LPO) and total antioxidant capacity (TAC) in both serum and follicular fluid (FF) of women with endometriosis after puncture. MATERIALS AND METHODS: In this cross-sectional study, a total number of sixty-three women younger than 40 years old with laparoscopy (gold standard for endometriosis diagnosis) indication underwent in vitro fertilization (IVF) program in the Royan Institute, Tehran, Iran from September 2013 to October 2014...
2017: Cell Journal
https://www.readbyqxmd.com/read/28031375/urinary-phytoestrogen-concentrations-are-not-associated-with-incident-endometriosis-in-premenopausal-women
#4
Sunni L Mumford, Jennifer Weck, Kurunthachalam Kannan, Germaine M Buck Louis
BACKGROUND: Phytoestrogens have been associated with subtle hormonal changes, but their effects on endometriosis are largely unknown. OBJECTIVE: We assessed the association between urinary concentrations of phytoestrogens and incident endometriosis. METHODS: We included an operative sample of 495 premenopausal women aged 18-44 y undergoing laparoscopies and laparotomies at 14 clinical sites between 2007 and 2009 and a general population sample of 131 women from the same geographic area who were matched on age and menstruation status...
December 28, 2016: Journal of Nutrition
https://www.readbyqxmd.com/read/28007589/rectovaginal-splenosis-an-unexpected-cause-of-dyspareunia-approached-by-laparoscopy
#5
Hélder Ferreira, Cristina Maciel, Alexandre Morgado, António Pereira
STUDY OBJECTIVE: To demonstrate the technique of laparoscopic approach in a rare case of rectovaginal splenosis with severe dyspareunia and dyschesia. DESIGN: A step-by-step explanation of the patient's condition, diagnosis, surgical technique, and postoperative results. SETTING: Splenosis consists of ectopic functioning splenic tissue that can be located anywhere within the abdomen or pelvis. Fragments are often multiple and range in diameter from a few millimeters to a few centimeters...
December 19, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28003801/deep-infiltrating-endometriosis-affecting-the-urinary-tract-surgical-treatment-and-fertility-outcomes-in-2004-2013
#6
Liisu Saavalainen, Oskari Heikinheimo, Aila Tiitinen, Päivi Härkki
Urinary tract endometriosis (UTE) is a rare form of deep infiltrating endometriosis. We studied the operative treatment of UTE and evaluated postoperative recurrences and fertility outcomes. This is a retrospective cohort study of 53 women who underwent operative treatment for UTE in 2004-2013 at Helsinki University Hospital, and were followed-up until the end of 2014. The data were gathered from the hospital's electronic database. The main outcome measures were complications, reoperations, postoperative pregnancies, and deliveries...
2016: Gynecological Surgery
https://www.readbyqxmd.com/read/27992932/endometriosis-in-the-adolescent-patient
#7
Mallory A Stuparich, Nicole M Donnellan, Joseph S Sanfilippo
The recognition and management of endometriosis in the adolescent patient is challenging. A strong clinical suspicion for endometriosis should be maintained in the adolescent who suffers from acyclic pelvic pain as well as absenteeism from school and lack of participation in daily activities. Risk factors include the presence of an obstructive Mullerian anomaly, a family history of endometriosis, and conditions that prolong exposure to endogenous and exogenous estrogens. Empiric medical therapy with nonsteroidal anti-inflammatory drugs and combined oral contraceptive pills may be considered in most adolescents with endometriosis...
December 19, 2016: Seminars in Reproductive Medicine
https://www.readbyqxmd.com/read/27988516/laparoscopic-extravesical-submucosal-tunneling-ureteroneocystostomy-combined-with-psoas-hitch-for-medium-length-distal-ureteral-defects-in-adults
#8
Huijie Gong, Yiqin Lu, Yongji Yan, Zhenqi Wu, Wenfeng Gao, Haisheng Cheng, Yabing Wu, Yanfeng Li, Xuetao Ma, Jingbo Liu, Linfeng Dai
OBJECTIVE: This study aims to describe the technique and feasibility of laparoscopic submucosal tunneling ureteroneocystostomy in combination with psoas hitch to restore urinary tract continuity in patients showing medium-length distal ureteral defects. MATERIALS AND METHODS: From January 2012 to April 2016, a total of 13 patients (4 males and 9 females) with a mean age of 37 years were performed with the laparoscopic operation of ureteral submucosal tunneling reimplantation combined with psoas hitch...
December 17, 2016: Urologia Internationalis
https://www.readbyqxmd.com/read/27987404/diagnostic-accuracy-of-cancer-antigen-125-ca125-for-endometriosis-in-symptomatic-women-a-multi-center-study
#9
Martin Hirsch, James M N Duffy, Christine S Deguara, Colin J Davis, Khalid S Khan
STUDY OBJECTIVE: To assess the diagnostic accuracy of serum Cancer Antigen 125 (CA 125)≥30units/milliliter (u/ml) for diagnosing endometriosis in symptomatic women. STUDY DESIGN: Prospective observational cohort study including patients with symptoms of pelvic pain or subfertility undergoing elective diagnostic laparoscopy at two tertiary referral hospitals. We excluded patients suspected to have other gynecological pathology. We evaluated the accuracy of serum CA 125 (index test) with histologically confirmed endometriosis (reference standard)...
December 5, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27986972/effects-of-vitamin-d-on-endometriosis-related-pain-a-double-blind-clinical-trial
#10
Fariba Almassinokiani, Sepideh Khodaverdi, Masoud Solaymani-Dodaran, Peyman Akbari, Abdolreza Pazouki
BACKGROUND Endometriosis is a disabling disease of reproductive-age women. Dysmenorrhea, dyspareunia, and pelvic pain are the main symptoms of endometriosis. Its etiology is not clear. Endometriosis may have various causes, including vitamin D deficiency, but its effect is controversial. MATERIAL AND METHODS In this double-blind clinical trial, we enrolled patients with endometriosis diagnosed and treated by laparoscopy, with scores of at least 3 for of dysmenorrhea and/or pelvic pain at 8 weeks after surgical treatment...
December 17, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27984749/laparoscopic-management-of-ureteral-endometriosis-a-systematic-review
#11
REVIEW
J Cavaco-Gomes, M Martinho, J Gilabert-Aguilar, J Gilabert-Estélles
The optimal management of ureteral endometriosis (UE) is not yet well defined. The choice on surgical approach and type of procedure has been based both on surgeons' experience and the location and depth of the lesion. The aim of this study was to review evidence about laparoscopic management of ureteral endometriosis, including preoperative evaluation, surgical details and postoperative follow-up. PubMed Central and SCOPUS databases were searched to identify studies reporting cases of laparoscopically managed ureteral endometriosis and including data regarding preoperative findings, surgical interventions and postoperative follow-up...
December 12, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27932523/treatment-of-recurrent-ovarian-cysts-and-primary-infertility-by-iranian-traditional-medicine-a-case-report
#12
Mehdi Salehi, Mohammad Setayesh, Roshanak Mokaberinejad
Infertility is a medical and psychosocial problem with a high prevalence. There are different treatments for this problem in Iranian traditional medicine. A 28-year-old woman presented with the complaints of 4 emergency operations of the left ovarian cyst during 4 years and infertility. Diagnostic laparoscopy showed an ovarian cyst, adhesion, and endometriosis. Hysteroscopy was unremarkable. After 2 months of letrozole administration, the ovarian cyst ruptured again. Considering the failure of conventional treatments, Iranian traditional medicine products were administered to the patient...
December 8, 2016: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/27920341/serum-mir-451a-levels-are-significantly-elevated-in-women-with-endometriosis-and-recapitulated-in-baboons-papio-anubis-with-experimentally-induced-disease
#13
Warren B Nothnick, Tommaso Falcone, Niraj Joshi, Asgerally T Fazleabas, Amanda Graham
We have previously demonstrated that human microRNA-451a (miR-451a) endometriotic lesion expression is significantly higher compared to that of the corresponding eutopic endometrium. The objective of the current study was to examine the relationship between lesion and serum content of miR-451a and to determine the utility of serum miR-451a in distinguishing between women with and without visible signs of endometriosis. Eighty-one participants were enrolled in this study, 41 with confirmed endometriosis and 40 without visible signs of endometriosis at laparoscopy (n = 20) or symptoms of endometriosis (pain, infertility n = 20)...
December 5, 2016: Reproductive Sciences
https://www.readbyqxmd.com/read/27912770/endometriosis-associated-clear-cell-carcinoma-arising-in-caesarean-section-scar-a-case-report-and-review-of-the-literature
#14
Gabriella Ferrandina, Eleonora Palluzzi, Francesco Fanfani, Stefano Gentileschi, Anna Lia Valentini, Maria Vittoria Mattoli, Ilaria Pennacchia, Giovanni Scambia, Gianfranco Zannoni
BACKGROUND: Malignant transformation has been reported in approximately 1% of the endometriosis cases; herein, we report a case of clear cell endometrial carcinoma arising from endometriosis foci located within a caesarean section scar. CASE PRESENTATION: In November 2014, a Caucasian, 44-year-old woman was transferred to our institution because of severe respiratory failure due to massive lung embolism and rapid enlargement of a subcutaneous suprapubic mass. Abdomino-pelvic magnetic resonance showed a 10...
December 3, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27896253/study-of-dienogest-for-dysmenorrhea-and-pelvic-pain-associated-with-endometriosis
#15
Soo Ah Kim, Mi Jung Um, Han Kyoung Kim, Suk Jin Kim, Seo Ju Moon, Hyuk Jung
OBJECTIVE: To evaluate the effect of orally administered dienogest (DNG) for dysmenorrhea and pelvic pain associated with endometriosis. METHODS: For this study we recruited 89 patients with dysmenorrhea and pelvic pain associated with endometriosis diagnosed by laparoscopy. All patients complained of persistent dysmenorrhea and pelvic pain despite surgical treatment 6 months previously. After 6 months of DNG treatment, we used a 0 to 3 point verbal rating scale to measure the severity of disability in daily life due to dysmenorrhea and pelvic pain, and the use of analgesics...
November 2016: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/27856389/mini-laparoscopy-of-removal-partial-adnexae-at-the-time-of-hysterectomy
#16
António Gutierrez Setúbal, João Sequeira Alves, Olga Lavado, Joana Faria
STUDY OBJECTIVE: To describe our technique of mini laparoscopic adnexectomy or salpingectomy at the time of total laparoscopic hysterectomy DESIGN: Step-by-step video explanation of our technique SETTING: The advantages of laparoscopic surgery have been widely recognised in the past two decades: improved vision, exposure, reduction in operative trauma because of smaller incisions and more gentle tissue´s handling, that result in a faster postoperative recovery. The technology development has allowed the use of smaller caliber instruments while maintaining the high standard surgical performance...
November 14, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27793377/pathophysiologic-processes-have-an-impact-on-the-plasma-metabolomic-signature-of-endometriosis-patients
#17
Sara Vicente-Muñoz, Inmaculada Morcillo, Leonor Puchades-Carrasco, Vicente Payá, Antonio Pellicer, Antonio Pineda-Lucena
OBJECTIVE: To evaluate potential variations in the plasma metabolomic profile of endometriosis patients as a consequence of pathophysiologic alterations associated with this disorder. DESIGN: Prospective study. For each subject, a plasma sample was collected after overnight fasting and before surgery. SETTING: University medical center. PATIENT(S): The clinical cohort included 50 endometriosis patients, diagnosed at early (n = 6) and advanced (n = 44) stages of the disease, and 23 healthy women...
December 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27760569/abdominal-ectopic-pregnancy-after-in-vitro-fertilization-and-single-embryo-transfer-a-case-report-and-systematic-review
#18
REVIEW
Nicole Yoder, Reshef Tal, J Ryan Martin
BACKGROUND: Ectopic pregnancy is the leading cause of maternal morbidity and mortality during the first trimester and the incidence increases dramatically with assisted-reproductive technology (ART), occurring in approximately 1.5-2.1 % of patients undergoing in-vitro fertilization (IVF). Abdominal ectopic pregnancy is a rare yet clinically significant form of ectopic pregnancy due to potentially high maternal morbidity. While risk factors for ectopic pregnancy after IVF have been studied, very little is known about risk factors specific for abdominal ectopic pregnancy...
October 19, 2016: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/27729562/bone-marrow-stem-cell-chemotactic-activity-is-induced-by-elevated-cxcl12-in-endometriosis
#19
Irene Moridi, Ramanaiah Mamillapalli, Emine Cosar, Gulcin Sahin Ersoy, Hugh S Taylor
Endometriosis is an inflammatory gynecological disorder caused by the growth of endometrial tissue outside the uterus. Endometriosis produces chemokines, including CXCL12, that attract bone marrow cells to the lesions. In this study, we describe the expression, localization, and chemotactic activity of CXCL12 in endometriotic lesions. Biopsies were collected both from women with endometriosis undergoing laparoscopy and control endometrium from women without endometriosis. Expression of CXCl12 and CXCR4 messenger RNA was increased approximately 4- and 6-fold, respectively, in endometriosis compared to eutopic endometrium...
October 11, 2016: Reproductive Sciences
https://www.readbyqxmd.com/read/27726474/augmented-angiogenic-factors-expression-via-fp-signaling-pathways-in-peritoneal-endometriosis
#20
Halima Rakhila, Mahera Al-Akoum, Charles Doillon, Nicolas Lacroix-Pépin, Mathieu Leboeuf, Madeleine Lemyre, Ali Akoum, Marc Pouliot
CONTEXT: Angiogenesis is required for ectopic endometrial tissue growth. Our previous studies showed that prostaglandin F2α (PGF2α) biosynthetic enzymes and receptor were markedly elevated in endometriotic lesions and that PGF2α is a potent angiogenic factor in endothelial cells. OBJECTIVE: We sought to determine whether or not the F-prostanoid receptor modulates angiogenesis in ectopic stromal cells. DESIGN: Release of angiogenic factors by ectopic endometrial stromal cell primary cultures stimulated with PGF2αand exposed to agents that target PGF2α signaling was assessed...
December 2016: Journal of Clinical Endocrinology and Metabolism
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