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Ca 125 endometriosis

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https://www.readbyqxmd.com/read/29155007/rare-obstructive-mullerian-anomaly-with-endometriosis-and-elevated-ca-125
#1
Christina H Suh, Yi-Horng Lee, Adrian C Balica
No abstract text is available yet for this article.
November 15, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29077705/effects-of-acupuncture-for-the-treatment-of-endometriosis-related-pain-a-systematic-review-and-meta-analysis
#2
Yang Xu, Wenli Zhao, Te Li, Ye Zhao, Huaien Bu, Shilin Song
BACKGROUND: Endometriosis is a multifactorial, oestrogen-dependent, inflammatory, gynaecological condition that can result in long-lasting visceral pelvic pain and infertility. Acupuncture could be an effective treatment for endometriosis and may relieve pain. Our aim in the present study was to determine the effectiveness of acupuncture as a treatment for endometriosis-related pain. METHODS: In December 2016, six databases were searched for randomised controlled trials that determined the effectiveness of acupuncture in the treatment of endometriosis-related pain...
2017: PloS One
https://www.readbyqxmd.com/read/29017382/which-factors-are-associated-with-the-recurrence-of-endometrioma-after-cystectomy
#3
Mehmet Küçükbaş, Meryem Kurek Eken, Gülşah İlhan, Taylan Şenol, Dilşad Herkiloğlu, Bilge Kapudere
Endometrioma is the most common form of endometriosis and is a sign of wide-spread disease in symptomatic patients. Medical treatment options can be successful in endometrioma smaller than 1 cm, but ineffective for growing and symptomatic endometriomas. Conservative surgical interventions that preserve fertility, such as laparoscopic removal or destruction of endometriotic tissue or aspiration of cystic content are typically used to treat the condition. One of the most frustrating aspects of endometrioma treatment is disease recurrence...
October 10, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28808611/red-snappers-and-red-herrings-pelvic-tuberculosis-causing-elevated-ca-125-and-mimicking-advanced-ovarian-cancer-a-case-report-and-literature-review
#4
Johnnie Alphonse Yates, Olivia Ann Collis, Thanasak Sueblinvong, Tarquin Kamakana Collis
Female genital tuberculosis (FGTB) is a form of extra-pulmonary tuberculosis that has been primarily described in developing countries, where it is an important cause of infertility, ectopic pregnancy, and miscarriage. FGTB is rare in the United States and because its clinical presentation is non-specific and often insidious, FGTB may be misdiagnosed as a gynecologic malignancy or endometriosis. The tendency of tuberculosis to dramatically increase serum CA 125 levels contributes to the potential for FGTB to be mistaken for ovarian cancer in particular...
August 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/28660213/how-to-use-ca-125-more-effectively-in-the-diagnosis-of-deep-endometriosis
#5
Marco Aurelio Pinho Oliveira, Thiers Soares Raymundo, Leila Cristina Soares, Thiago Rodrigues Dantas Pereira, Alessandra Viviane Evangelista Demôro
Deep infiltrative endometriosis (DIE) is a severe form of the disease. The median time interval from the onset of symptoms to diagnosis of endometriosis is around 8 years. In this prospective study patients were divided into two groups: cases (34 DIE patients) and control (20 tubal ligation patients). The main objective of this study was to evaluate the performance of CA-125 measurement in the menstrual and midcycle phases of the cycle, as well as the difference in its levels between the two phases, for the early diagnosis of DIE...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28545269/-risk-factors-of-endometriosis-associated-ovarian-carcinoma-in-women-aged-45-years-and-older
#6
Z X He, S Wang, Z F Li, L Zhu, J H Leng, J H Lang
Obiective: To explore the risk factors of endometriosis-associated ovarian cancer (EAOC) in women with ovarian endometriosis aged 45 years and older in China. Methods: The medical records of total 1 038 women aged 45 years and older with a surgicopathological diagnosis of ovarian endometriosis treated at Peking Union Medical College Hospital from December 1994 to December 2014 were reviewed. Histology evaluation determined ovarian endometriosis with (n=30) or without (n=1 008) ovarian cancer. Results: (1) There were 30 (2...
May 25, 2017: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/28355687/-clinical-analysis-of-pelvic-abscess-with-endometriosis
#7
Y T Liu, H H Shi, X Yu, S Wang, Q B Fan, H Y Liu
Objective: To investigate the clinical features, diagnosis and treatments of pelvic abscess with endometriosis. Methods: A retrospective analysis was performed on 129 cases of pelvic abscess in Peking Union Medical College Hospital from January 2000 to January 2016. Among them, 34 women with endometriosis were divided into the study group and the others were in the control group. The clinical characteristics, therapeutic regimens and outcomes were compared. Results: (1) General conditions: there were no statistic differences between the two groups in age, WBC, serum CA(125), intrauterine device in use, pelvic inflammatory disease history; while incidence rates of dysmenorrhea (65%, 22/34) and infertility (21%, 7/34) in the study group were higher than those in the control group (all P<0...
March 25, 2017: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/28271701/an-update-on-the-biological-markers-of-endometriosis
#8
Razvan Socolov, Demetra Socolov, Allia Sindilar, Ioana Pavaleanu
BACKGROUND: Endometriosis is a disease that affects 7-10% of reproductive-age women. When its diagnosis is delayed, its management becomes more difficult. Both for earlier detection and for therapeutic follow-up, discovering noninvasive biological markers with good specificity for this disease is a promising aspect of its research. We analyzed the recent data in the literature regarding these markers to determine which were worth following. MATERIALS AND METHODS: This literature review focused on medical data reported in the last 6 years (2011-2016)...
March 7, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28254227/unexpected-epithelial-ovarian-cancers-arising-from-presumed-endometrioma-a-10-year-retrospective-analysis
#9
Hsin-Hong Kuo, Chen-Ying Huang, Shir-Hwa Ueng, Kuan-Gen Huang, Chyi-Long Lee, Chih-Feng Yen
OBJECTIVE: To evaluate the incidence and prognosis of unexpected epithelial ovarian cancers (EOCs) occurring in presumed benign endometrioma. MATERIALS AND METHODS: Patients who underwent primary surgery at Chang Gung Memorial Hospital between November 2003 and October 2013 were searched with the Systematized Nomenclature of Medicine code followed by chart review. RESULTS: The incidence of unexpected EOCs in presumed ovarian endometrioma was 0...
February 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28008424/correlation-of-ca-125-serum-level-and-clinico-pathological-characteristic-of-patients-with-endometriosis
#10
Mojgan Karimi-Zarchi, Najmeh Dehshiri-Zadeh, Leili Sekhavat, Fahime Nosouhi
BACKGROUND: Cancer antigen 125 (CA-125) is a glycoprotein biomarker that is used in women with pelvic masses such as endometriosis and maybe is useful in practice of patients suspicious to endometriosis. OBJECTIVE: The aim of this study was to evaluate the association between preoperative serum CA-125 levels and clinic pathological characteristic in women with endometriosis, and find out the best serum CA-125 levels cut-off in pre and post menopause women. MATERIALS AND METHODS: Serum CA-125 levels in 87 women aged 21-54 years suspected to endometriosis with pelvic pain, dysmenorrhea, or dyspareunia were measured preoperatively...
November 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27987404/diagnostic-accuracy-of-cancer-antigen-125-ca125-for-endometriosis-in-symptomatic-women-a-multi-center-study
#11
Martin Hirsch, James M N Duffy, Christine S Deguara, Colin J Davis, Khalid S Khan
STUDY OBJECTIVE: To assess the diagnostic accuracy of serum Cancer Antigen 125 (CA 125)≥30units/milliliter (u/ml) for diagnosing endometriosis in symptomatic women. STUDY DESIGN: Prospective observational cohort study including patients with symptoms of pelvic pain or subfertility undergoing elective diagnostic laparoscopy at two tertiary referral hospitals. We excluded patients suspected to have other gynecological pathology. We evaluated the accuracy of serum CA 125 (index test) with histologically confirmed endometriosis (reference standard)...
March 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27912770/endometriosis-associated-clear-cell-carcinoma-arising-in-caesarean-section-scar-a-case-report-and-review-of-the-literature
#12
REVIEW
Gabriella Ferrandina, Eleonora Palluzzi, Francesco Fanfani, Stefano Gentileschi, Anna Lia Valentini, Maria Vittoria Mattoli, Ilaria Pennacchia, Giovanni Scambia, Gianfranco Zannoni
BACKGROUND: Malignant transformation has been reported in approximately 1% of the endometriosis cases; herein, we report a case of clear cell endometrial carcinoma arising from endometriosis foci located within a caesarean section scar. CASE PRESENTATION: In November 2014, a Caucasian, 44-year-old woman was transferred to our institution because of severe respiratory failure due to massive lung embolism and rapid enlargement of a subcutaneous suprapubic mass. Abdomino-pelvic magnetic resonance showed a 10...
December 3, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27745918/prognostic-value-of-endometriosis-in-patients-with-stage-i-ovarian-clear-cell-carcinoma-experiences-at-three-academic-institutions
#13
MULTICENTER STUDY
Huimin Bai, Dongyan Cao, Fang Yuan, Guihua Sha, Jiaxin Yang, Jie Chen, Yue Wang, Zhenyu Zhang, Keng Shen
OBJECTIVES: To investigate the prognostic value of endometriosis in patients with stage I ovarian clear cell carcinoma (OCCC). METHODS: The medical records of patients with stage I OCCC who had undergone complete staging surgery followed by systemic chemotherapy were retrospectively reviewed. RESULTS: A total of 237 women were included in this study. Univariate analysis revealed that the patients with endometriosis-associated ovarian carcinoma (EAOC) had significantly improved recurrence-free survival (RFS) and overall survival (OS) than those without EAOC (5-year RFS: 91...
December 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/27678941/endometriosis-presenting-with-massive-ascites-and-an-elevated-ca-125
#14
S Farag, L Nguyen, T Kalir, D Fishman
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27602187/evaluation-of-he4-ca-125-risk-of-ovarian-malignancy-algorithm-roma-and-risk-of-malignancy-index-rmi-in-the-preoperative-assessment-of-patients-with-adnexal-mass
#15
Khawla Al Musalhi, Manal Al Kindi, Faiza Al Aisary, Fatma Ramadhan, Thuraya Al Rawahi, Khalsa Al Hatali, Waad-Allah Mula-Abed
OBJECTIVES: To evaluate the validity and compare the performance of cancer antigen-125 (CA-125), human epididymis protein 4 (HE4), the risk of malignancy index (RMI), and the risk of ovarian malignancy algorithm (ROMA) in the diagnosis of ovarian cancer in patients with ovarian lesions discovered during their preoperative work-up investigations. METHODS: This prospective, cross-sectional study looked at patients who attended the gynecology department at the Royal Hospital, Muscat, from 1 March 2014 to 30 April 2015, for the evaluation of an ovarian lesion...
September 2016: Oman Medical Journal
https://www.readbyqxmd.com/read/27485360/panel-of-autoimmune-markers-for-noninvasive-diagnosis-of-minimal-mild-endometriosis
#16
MULTICENTER STUDY
Rahul Gajbhiye, Trupti Bendigeri, Arun Ghuge, Kashmira Bhusane, Shahina Begum, Neeta Warty, Raj Sawant, Kedar Padte, Anil Humane, Pramathes Dasmahapatra, Anahita Chauhan, Shagufta Khan
Endometriosis, characterized by the presence of endometrial-like tissue at extrauterine sites, is a common, chronic, estrogen-dependent, inflammatory condition associated with pelvic pain, subfertility, dysmenorrhea, and dyspareunia, affecting about 10% of reproductive-age women in any population. The diagnosis of endometriosis is usually delayed on an average by 8 to 11 years leading to significant consequences in terms of disease progression. The current study was aimed to validate enzyme-linked immunosorbent assay based on the epitopes of stomatin-like protein 2, tropomodulin 3 (TMOD3), and tropomyosin 3 (TPM3) for diagnosis of minimal-mild endometriosis (revised American Fertility Society Classification (rAFS) stage I-II) and to compare the performance with the reported markers: cancer antigen (CA) 125, CA19-9, α-enolase, Serine/threonine-protein kinase (PDIK1L), and syntaxin 5...
March 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/27405583/combination-of-the-non-invasive-tests-for-the-diagnosis-of-endometriosis
#17
REVIEW
Vicki Nisenblat, Lucy Prentice, Patrick M M Bossuyt, Cindy Farquhar, M Louise Hull, Neil Johnson
BACKGROUND: About 10% of women of reproductive age suffer from endometriosis, a costly chronic disease causing pelvic pain and subfertility. Laparoscopy is the gold standard diagnostic test for endometriosis, but is expensive and carries surgical risks. Currently, there are no non-invasive tests available in clinical practice to accurately diagnose endometriosis. This review assessed the diagnostic accuracy of combinations of different non-invasive testing modalities for endometriosis and provided a summary of all the reviews in the non-invasive tests for endometriosis series...
July 13, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27330011/endometriosis-leads-to-an-increased-trefoil-factor-3-concentration-in-the-peritoneal-cavity-but-does-not-alter-systemic-levels
#18
Diana Henze, Wolf-Dietrich Doecke, Daniela Hornung, Inoncent Agueusop, Oliver von Ahsen, Kathrin Machens, Arndt A Schmitz, Isabella Gashaw
This study analyzed whether trefoil factor 3 (TFF3) is locally elevated and correlated with common biomarkers and inflammatory processes in endometriosis. Peritoneal fluid (PF) was obtained from 50 women and serum from 124 women with or without endometriosis. Experimental endometriosis was induced in female C57BL/6 mice by syngeneic transplantation of uterine tissue to the abdominal wall. Levels of TFF3 in PF of women with endometriosis were significantly increased ( P < .05) and correlated with local levels of known biomarkers for endometriosis: cancer antigen (CA) 125, CA-19-9, interleukin 8, monocyte chemotactic protein 1, and matrix metalloproteinase 7...
February 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/27173590/diagnostic-accuracy-of-cancer-antigen-125-for%C3%A2-endometriosis-a-systematic-review-and-meta-analysis
#19
REVIEW
M Hirsch, Jmn Duffy, C J Davis, M Nieves Plana, K S Khan
BACKGROUND: The development of a non-invasive and accurate diagnostic biomarker for endometriosis is urgently needed. OBJECTIVE: Evaluate the diagnostic accuracy of serum cancer antigen 125 (CA 125) for endometriosis. SEARCH STRATEGY: We searched EMBASE, MEDLINE, and Web of Science from inception to January 2016. SELECTION CRITERIA: Diagnostic accuracy studies of serum CA 125 (index test) for histologically confirmed endometriosis (reference standard) were included...
October 2016: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27132058/blood-biomarkers-for-the-non-invasive-diagnosis-of-endometriosis
#20
REVIEW
Vicki Nisenblat, Patrick M M Bossuyt, Rabia Shaikh, Cindy Farquhar, Vanessa Jordan, Carola S Scheffers, Ben Willem J Mol, Neil Johnson, M Louise Hull
BACKGROUND: About 10% of reproductive-aged women suffer from endometriosis, a costly chronic disease causing pelvic pain and subfertility. Laparoscopy is the gold standard diagnostic test for endometriosis, but is expensive and carries surgical risks. Currently, there are no non-invasive or minimally invasive tests available in clinical practice to accurately diagnose endometriosis. Although other reviews have assessed the ability of blood tests to diagnose endometriosis, this is the first review to use Cochrane methods, providing an update on the rapidly expanding literature in this field...
May 1, 2016: Cochrane Database of Systematic Reviews
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