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robotic single site

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https://www.readbyqxmd.com/read/28086908/hiv-integration-sites-in-latently-infected-cell-lines-evidence-of-ongoing-replication
#1
Jori Symons, Abha Chopra, Eva Malantinkova, Ward De Spiegelaere, Shay Leary, Don Cooper, Chike O Abana, Ajantha Rhodes, Simin D Rezaei, Linos Vandekerckhove, Simon Mallal, Sharon R Lewin, Paul U Cameron
BACKGROUND: Assessing the location and frequency of HIV integration sites in latently infected cells can potentially inform our understanding of how HIV persists during combination antiretroviral therapy. We developed a novel high throughput sequencing method to evaluate HIV integration sites in latently infected cell lines to determine whether there was virus replication or clonal expansion in these cell lines observed as multiple integration events at the same position. RESULTS: We modified a previously reported method using random DNA shearing and PCR to allow for high throughput robotic processing to identify the site and frequency of HIV integration in latently infected cell lines...
January 13, 2017: Retrovirology
https://www.readbyqxmd.com/read/28078466/does-stoma-site-specimen-extraction-increase-postoperative-ileostomy-complication-rates
#2
Wanglin Li, Cigdem Benlice, Luca Stocchi, Hermann Kessler, Emre Gorgun, Meagan Costedio
BACKGROUND: Minimizing incisions has the potential to decrease hernia formation and wound complications following laparoscopic surgery. It is currently unknown if using the stoma site for specimen extraction affects outcomes. This study aims to evaluate the impact of stoma site extraction on postoperative complication rates in laparoscopic colorectal surgery. METHODS: After IRB approval, a retrospective comparative review of 738 consecutive patients (405 M) who underwent laparoscopic colorectal surgery with ileostomy between January 2008 and December 2014 was performed...
January 11, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28058471/a-comparative-study-of-outcomes-between-single-site-robotic-and-multi-port-laparoscopic-cholecystectomy-an-experience-from-a-tertiary-care-center
#3
Banujan Balachandran, Theadore A Hufford, Taha Mustafa, Kunal Kochar, Suela Sulo, Joubin Khorsand
BACKGROUND: The aim of this study was to compare the outcomes of single-site robotic cholecystectomy with multi-port laparoscopic cholecystectomy within a high-volume tertiary health care center. METHODS: A retrospective analysis of prospectively maintained data was conducted on patients undergoing single-site robotic cholecystectomy or multi-port laparoscopic cholecystectomy between October 2011 and July 2014. A single surgeon performed all the surgeries included in the study...
January 5, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28038476/single-site-robotic-radical-hysterectomy-and-sentinel-lymphnode-biopsy-in-cervical-cancer-a-case-report
#4
Alexandre Silva E Silva, Rodrigo Pinto Fernandes, Marcia Pereira de Araujo, João Paulo Mancusi de Carvalho, Filomena Marino Carvalho, Giovani Mastrantônio Favero, Jesus Paula Carvalho
Robotic surgeries for cervical cancer have several advantages compared with laparotomic or laparoscopic surgeries. Robotic single-site surgery has many advantages compared with the multiport approach, but its safety and feasibility are not established in radical oncologic surgeries. We report a case of a Federation of Gynecology and Obstetrics (FIGO) stage IB1 cervical carcinoma whose radical hysterectomy, sentinel lymph node mapping, and lymph node dissection were entirely performed by robotic single-site approach...
December 30, 2016: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/28034772/incidence-and-outcomes-of-ventral-hernia-repair-after-robotic-retropubic-prostatectomy-a-retrospective-cohort-of-570-consecutive-cases
#5
A Ashfaq, K Ahmadieh, A A Shah, E M Garvey, A B Chapital, D J Johnson, K L Harold
BACKGROUND: Robotic retropubic prostatectomy (RRP) has become one of the most commonly performed robotic procedures in the United States. Ventral hernia (VH) has been increasingly recognized as an important complication after laparoscopic procedures, in general. However, data related to VH after robotic procedures is relatively scarce, especially after RRP. With increasing popularity of RRP, the purpose of this study was to look at the incidence of VH and outcomes of ventral hernia repair (VHR) after RRP...
December 26, 2016: International Journal of Surgery
https://www.readbyqxmd.com/read/28011096/minimally-invasive-radical-hysterectomy-for-cervical-cancer-is-associated-with-reduced-morbidity-and-similar-survival-outcomes-compared-with-laparotomy
#6
Elisabeth Diver, Emily Hinchcliff, Allison Gockley, Alexander Melamed, Leah Contrino, Sarah Feldman, Whitfield Growdon
STUDY OBJECTIVE: In cervical cancer, there are limited randomized trials to indicate whether patient outcomes are equivalent after radical hysterectomy (RH) via minimally invasive (MIS) or traditional laparotomy (XL) approach. The aim of this study was to assess patient outcomes of women with cervical cancer undergoing upfront RH at two large academic institutions to determine if mode of surgery affects patient outcomes. DESIGN: A retrospective cohort study Design classification: Canadian Task Force Classification II-1 SETTING: Two academic medical institutions in the United States from 2000 to 2013 PATIENTS: Women undergoing upfront RH for cervical cancer INTERVENTION: Minimally invasive techniques (laparoscopic and robotic) for RH, as compared with XL MEASUREMENTS AND MAIN RESULTS: 383 women met eligibility requirements...
December 20, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27992297/single-port-robotic-cholecystectomy-in-pediatric-patients-single-institution-experience
#7
Armando Rosales-Velderrain, Fuad Alkhoury
INTRODUCTION: Modifications to conventional laparoscopic cholecystectomy are aimed to decrease abdominal pain and improve cosmetic results. Single-port robotic cholecystectomy is a safe and feasible approach that has been reported in adults, though reports are limited in children. This study aims to report our experience with single-port robotic cholecystectomy in children, and to evaluate the safety, feasibility, and outcomes of this approach. METHODS: After single-port robotic approach was available at our institution, we prospectively followed our patients who underwent a single-port robotic cholecystectomy from March 2013 to May 2015 in our children's hospital...
December 19, 2016: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/27987068/single-site-robotic-assisted-apical-lateral-suspension-ss-r-als-for-advanced-pelvic-organ-prolapse-first-case-reported
#8
Andrea Giannini, Eleonora Russo, Paolo Mannella, Tommaso Simoncini
While single-port laparoscopy for gynecological surgery is technically challenging, the Da Vinci Single-Site(®) robotic surgery platform may help to overcome some of the difficulties of this rapidly evolving technique. The authors of this article present the first case of single-incision, robotic apical lateral suspension (R-ALS) using this device in pelvic organ prolapse (POP) surgery. A 71-year-old female with advanced symptomatic anterior and apical prolapse (POP-Q stage III/III) was operated with a single-site approach using the Da Vinci Single-Site(®) robotic surgery device...
December 17, 2016: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/27981823/robotic-single-port-cholecystectomy-current-data-and-future-perspectives
#9
Anastasios Angelou, Athanasios Skarmoutsos, Georgios A Margonis, Demetrios Moris, Christos Tsigris, Emmanouil Pikoulis
INTRODUCTION: Minimally invasive techniques are used more and more frequently. Since conventional laparoscopic approach has been the gold standard, surgeons in their effort to further reduce the invasiveness of conventional laparoscopic cholecystectomy have adopted Single Incision approach. The widespread adoption of robotics has led to the inevitable hybridization of robotic technology with laparoendoscopic single-site surgery (LESS). As a result, employment of the da Vinci surgical system may allow greater surgical maneuverability, improving ergonomics...
December 16, 2016: Minerva Chirurgica
https://www.readbyqxmd.com/read/27878458/totally-extraperitoneal-tep-bilateral-hernioplasty-using-the-single-site%C3%A2-robotic-da-vinci-platform-dv-ss-tep-description-of-the-technique-and-preliminary-results
#10
A Cestari, A C Galli, M N Sangalli, M Zanoni, M Ferrari, G Roviaro
PURPOSE: Laparoendoscopic single site totally extraperitoneal (TEP) hernia repair showed to be a feasible alternative to conventional laparoscopic hernia repair; nevertheless single site surgery, with the loss of instruments triangulation can be a demanding procedure. To overcome those hurdles, the Single Site® (SS) platform of the da Vinci (DV) Si robotic system enables to perform surgical procedures through a 25-mm skin incision, with a stable 3D vision and restoring an adequate triangulation of the surgical instruments...
November 22, 2016: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/27867846/what-s-the-best-minimal-invasive-approach-to-pediatric-nephrectomy-and-heminephrectomy-conventional-laparoscopy-cl-single-site-less-or-robotics-ras
#11
REVIEW
Holger Till, Ali Basharkhah, Andras Hock
BACKGROUND: Conventional laparoscopy (CL) using 3-5 mm ports has become the goldstandard for pediatric nephrectomy (N), heminephrectomy (HN) and heminephrecto-ureterectomy (HNU) for many years now. Recently the spectrum of minimal invasive surgery (MIS) has been extended by variants like laparoendoscopic single-site surgery (LESS) or robot-assisted surgery (RAS). However such technical developments tend to drive surgical euphoria and feasibility studies, but may miss adequate academic research about function and proven patients' benefits...
October 2016: Translational pediatrics
https://www.readbyqxmd.com/read/27867048/feasibiility-and-learning-curve-of-robotic-laparo-endoscopic-single-site-surgery-in-gynecology
#12
Alexandre Buckley de Meritens, Julia Kim, Helen Dinkelspiel, Eloise Chapman-Davis, Thomas Caputo, Kevin Holcomb
Single-site laparoscopy has proven to be a desirable option for patients undergoing gynecologic surgery with some studies indicating improved cosmesis and less perioperative pain compared to standard approaches. This study describes the safety and feasibility of a novel robotic laparo-endoscopic single-site surgery (R-LESS) platform as it is incorporated into a surgeon's practice with extensive multiport robotic surgical experience but limited laparo-endoscopic single-site experience. We reviewed 83 women undergoing R-LESS by a single surgeon from September 2013 through August 2015...
November 17, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27864724/cosmesis-patient-satisfaction-and-quality-of-life-after-da-vinci-single-site-cholecystectomy-and-multiport-laparoscopic-cholecystectomy-short-term-results-from-a-prospective-multicenter-randomized-controlled-trial
#13
Omar Yusef Kudsi, Andres Castellanos, Srinivas Kaza, Justin McCarty, Eugene Dickens, David Martin, Frederick M Tiesenga, Konstantinos Konstantinidis, Petros Hirides, Shilpa Mehendale, Anthony Gonzalez
BACKGROUND: Single-incision laparoscopic cholecystectomy evolved from the traditional multiport laparoscopic technique. Prior trials have demonstrated improved cosmesis with the single-incision technique. Robotic single-site surgery minimizes the technical difficulties associated with laparoscopic single-incision approach. This is the first prospective, randomized, controlled study comparing robotic single-site cholecystectomy (RSSC) and multiport laparoscopic cholecystectomy (MPLC) in terms of cosmesis and patient satisfaction...
November 18, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27860142/single-incision-robotic-cholecystectomy-a-special-emphasis-on-utilization-of-transparent-glove-ports-to-overcome-limitations-of-single-site-port
#14
Hongeun Lee, Doo-Ho Lee, Hongbeom Kim, Youngmin Han, Sun-Whe Kim, Jin-Young Jang
BACKGROUND: The current robotic platform overcomes some limitations of single-incision laparoscopic cholecystectomy (SILC), however, whether robotic surgery is a safe and feasible approach must be investigated. METHODS: Patients referred for elective surgery willing to undergo single-incision robotic cholecystectomy (SIRC) by consent were enrolled. All procedures were performed by the same team using the same surgical equipment. RESULTS: Thirty patients underwent SIRC...
November 17, 2016: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://www.readbyqxmd.com/read/27856385/wound-infiltration-with-extended-release-versus-short-acting-bupivacaine-before-laparoscopic-hysterectomy-a-randomized-controlled-trial
#15
Kenneth I Barron, Georgine M Lamvu, R Cole Schmidt, Matthew Fisk, Emily Blanton, Insiyyah Patanwala
STUDY OBJECTIVE: To evaluate if pre-incision infiltration with extended-release liposomal bupivacaine provides improved overall pain relief compared to 0.25% bupivacaine after laparoscopic or robotic-assisted hysterectomy. DESIGN: Single center double-masked randomized controlled trial (Canadian Task Force Classification I). SETTING: Tertiary-care community hospital PATIENTS: Patients recruited from July 2015 through January 2016. Sixty-four patients were randomized and 59 were analyzed for the primary outcome...
November 14, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27815041/feasibility-of-robotic-assisted-laparoendoscopic-single-site-surgery-in-the-gynecologic-oncology-setting
#16
Lea A Moukarzel, Amanda N Fader, Edward J Tanner
STUDY OBJECTIVE: To assess the feasibility of incorporating robotic laparoendoscopic single-site (R-LESS) surgery into gynecologic oncology care. DESIGN: Retrospective study (Canadian Task Force classification II-3). SETTING: Academic university hospital. PATIENTS: Patients undergoing R-LESS hysterectomy for gynecologic malignancies, preinvasive disease, or risk reduction performed by a single gynecologic oncologist between 2014 and 2016...
November 1, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27796599/robotic-assisted-colorectal-surgery-in-obese-patients-a-case-matched-series
#17
Jeffrey N Harr, Samuel Luka, Aman Kankaria, Yen-Yi Juo, Samir Agarwal, Vincent Obias
BACKGROUND: Reports demonstrate laparoscopic colorectal surgery in obese patients is associated with higher conversion to laparotomy and complication rates. While several advantages of robotic-assisted surgery have been reported, outcomes in obese patients have not been adequately studied. Therefore, this study compares outcomes of robotic-assisted surgery in non-obese and obese patients. METHODS: A retrospective review of 331 consecutive robotic procedures performed at a single institution between 2009 and 2015 was performed...
October 27, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27774510/robotic-qm-mm-driven-maturation-of-antibody-combining-sites
#18
Ivan V Smirnov, Andrey V Golovin, Spyros D Chatziefthimiou, Anastasiya V Stepanova, Yingjie Peng, Olga I Zolotareva, Alexey A Belogurov, Inna N Kurkova, Natalie A Ponomarenko, Matthias Wilmanns, G Michael Blackburn, Alexander G Gabibov, Richard A Lerner
In vitro selection of antibodies from large repertoires of immunoglobulin (Ig) combining sites using combinatorial libraries is a powerful tool, with great potential for generating in vivo scavengers for toxins. However, addition of a maturation function is necessary to enable these selected antibodies to more closely mimic the full mammalian immune response. We approached this goal using quantum mechanics/molecular mechanics (QM/MM) calculations to achieve maturation in silico. We preselected A17, an Ig template, from a naïve library for its ability to disarm a toxic pesticide related to organophosphorus nerve agents...
October 2016: Science Advances
https://www.readbyqxmd.com/read/27766718/transoral-robotic-surgery-implementation-as-a-tool-in-head-and-neck-surgery-a-single-centre-australian-experience
#19
Nir Hirshoren, Olivia Ruskin, Tsien Fua, Stephen Kleid, Matthew Magarey, Benjamin Dixon
BACKGROUND: Transoral robotic surgery (TORS) is now a well-validated technique for resection of head and neck cancers. Benefits include reduced patient morbidity, swallowing preservation and rationalization of adjuvant therapies. METHODS: This was a single-centre, retrospective review of 35 patients who underwent TORS of oro-, retro- and parapharyngeal tumours between March 2014 and August 2015. Outcome measures included resection margins, swallowing function and impact on post-operative radiotherapy...
October 21, 2016: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/27757400/single-port-plus-an-additional-port-robotic-complete-mesocolic-excision-and-intracorporeal-anastomosis-using-a-robotic-stapler-for-right-sided-colon-cancer
#20
Sung Uk Bae, Woon Kyung Jeong, Seong Kyu Baek
The concept of complete mesocolic excision and central vascular ligation for colonic cancer has been recently introduced. The paper describes a technique of right-sided complete mesocolic excision and intracorporeal anastomosis by using a single-port robotic approach with an additional conventional robotic port. We performed a single-port plus an additional port robotic surgery using the Da Vinci Single-Site platform via the Pfannenstiel incision and the wristed robotic instruments via an additional robotic port in the left lower quadrant...
October 2016: Annals of Surgical Treatment and Research
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