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https://www.readbyqxmd.com/read/28214943/comparison-of-mesh-fixation-and-non-fixation-in-laparoscopic-totally-extraperitoneal-inguinal-hernia-repair
#1
K Buyukasik, A Ari, B Akce, C Tatar, O Segmen, H Bektas
PURPOSE: The purpose of this study was to compare laparoscopic total extraperitoneal (TEP) hernia repair procedures with or without mesh fixation for non-recurrent inguinal hernia. METHODS: 100 male patients with non-recurrent inguinal hernia (62 unilateral and 38 bilateral) were included in the study. The patients were randomly assigned to either the mesh fixation group (n = 50) or the mesh non-fixation group (n = 50). The operative and follow-up data of the two groups were analyzed and compared in terms of recurrence rates, postoperative pain, length of hospital stay, and postoperative changes in testicular arterial blood flow...
February 18, 2017: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/28214572/clinical-relevance-of-oxidation-reduction-potential-in-the-evaluation-of-male-infertility
#2
Ashok Agarwal, Siew May Wang
Objectives To evaluate 1) the relationship between oxidation-reduction potential (ORP) and abnormal sperm quality, 2) changes in ORP and sperm parameters over time, in search of a potential surrogate marker of poor sperm quality that may assist in the diagnosis of oxidative stress- related male infertility. Methods 194 infertile men were included and 28 patients were identified to have repeated semen analyses and ORP measurements. The semen samples obtained were categorized into normal and abnormal sperm parameters based on the World Health Organization (WHO) 5(th) edition guidelines...
February 15, 2017: Urology
https://www.readbyqxmd.com/read/28214493/the-value-of-near-infrared-spectroscopy-for-the-assessment-of-calf-muscle-function-in-venous-patients
#3
Spyros N Vasdekis, Ioannis Tzemailas, Constantine N Antonopoulos, Sotiria Mastoraki, George K Mantas, Andreas Lazaris
OBJECTIVE: Near-infrared spectroscopy (NIRS) is a noninvasive technique with the potential to determine the degree of tissue oxygenation. The aim of the current study was to investigate the use of NIRS as a reliable method of detecting calf muscle pump dysfunction in groups of patients with venous disease. METHODS: Patients with superficial venous insufficiency (SVI) or history of deep venous thrombosis (DVT) were classified according to the comprehensive classification system for chronic venous disorders (clinical class, etiology, anatomy, and pathophysiology) and compared with controls (GROUP variable)...
March 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28214393/flow-cytometric-bacterial-cell-counts-challenge-conventional-heterotrophic-plate-counts-for-routine-microbiological-drinking-water-monitoring
#4
REVIEW
S Van Nevel, S Koetzsch, C R Proctor, M D Besmer, E I Prest, J S Vrouwenvelder, A Knezev, N Boon, F Hammes
Drinking water utilities and researchers continue to rely on the century-old heterotrophic plate counts (HPC) method for routine assessment of general microbiological water quality. Bacterial cell counting with flow cytometry (FCM) is one of a number of alternative methods that challenge this status quo and provide an opportunity for improved water quality monitoring. After more than a decade of application in drinking water research, FCM methodology is optimised and established for routine application, supported by a considerable amount of data from multiple full-scale studies...
February 8, 2017: Water Research
https://www.readbyqxmd.com/read/28213959/combining-induced-pluripotent-stem-cells-and-genome-editing-technologies-for-clinical-applications
#5
Chia-Yu Chang, Hsiao-Chien Ting, Hong-Lin Su, Jing-Ren Jeng
In this review, we introduce current developments in induced pluripotent stem cells (iPSCs), site-specific nuclease (SSN)-mediated genome editing tools, and the combined application of these two novel technologies in biomedical research and therapeutic trials. The sustainable pluripotent property of iPSCs in vitro not only provides unlimited cell sources for basic research but also benefits precision medicines for human diseases. In addition, rapidly evolving SSN tools efficiently tailor genetic manipulations for exploring gene functions and can be utilized to correct genetic defects of congenital diseases in the near future...
February 17, 2017: Cell Transplantation
https://www.readbyqxmd.com/read/28213707/hydropower-reservoirs-cytotoxic-and-genotoxic-assessment-using-the-allium-cepa-root-model
#6
Cassiano Lazarotto Rambo, Patrícia Zanotelli, Daniela Dalegrave, Dinara De Nez, Jozimar Szczepanik, Fábio Carazek, Francini Franscescon, Denis Broock Rosemberg, Anna Maria Siebel, Jacir Dal Magro
Hydropower offers a reliable source of electricity in several countries, and Brazil supplies its energy needs almost entirely through hydropower plants. Nevertheless, hydropower plants comprise large buildings and water reservoirs and dams, resulting in huge ecological disruptions. Here, we analyzed the impact of four hydropower reservoirs construction in metals and pesticides incidence and the cytotoxic and genotoxic potential of sediment elutriate of rivers from southern Brazil. Our analyses have evidenced the elevated incidence of different metals (lead, iron, cadmium, and chrome) and pesticides (methyl parathion, atrazine, and 2,4-dichlorophenoxyacetic acid)...
February 17, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28213563/development-and-validation-of-a-patient-reported-outcome-instrument-for-skin-involvement-in-patients-with-systemic-sclerosis
#7
Ada Man, Jeannette K Correa, Jessica Ziemek, Robert W Simms, David T Felson, Robert Lafyatis
OBJECTIVES: We developed a patient-reported outcome (PRO) instrument to assess the skin-related quality of life in patients with systemic sclerosis (SSc). METHODS: Participants with SSc provided input on skin-related health effects through focus groups. We developed items for scleroderma skin PRO (SSPRO) to encompass these effects. Further consideration from cognitive interviews and an expert panel led to reduction and modification of items. A 22-item SSPRO was field tested...
February 17, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28213339/classifying-empirically-valid-and-clinically-meaningful-change-in-eating-disorders-using-the-eating-disorders-inventory-version-2-edi-2
#8
David Clinton, Andreas Birgegård
The study examined the ability of the EDI-2 to classify empirically valid and clinically meaningful change using clinical significance and the Reliable Change Index (CS/RCI), and compared CS/RCI to classification based on diagnostic change. Eating disorder (ED) patients (N=363) were assessed at intake and after 36months on measures of ED and psychiatric symptoms, self-image, interpersonal relationships, treatment satisfaction and general outcome. Patients were categorized using a four-way classification scheme as "Deteriorated", "Unchanged", "Improved" or "No ED"; and using a two-way classification scheme as either in remission or not in remission...
February 9, 2017: Eating Behaviors
https://www.readbyqxmd.com/read/28213338/a-uniaxial-cyclic-compression-method-for-characterizing-the-rheological-and-textural-behaviors-of-mechanically-dewatered-sewage-sludge
#9
Fenglin Liang, Martial Sauceau, Gilles Dusserre, Patricia Arlabosse
The mechanically dewatered sewage sludge with total solid content around 20% on a weight basis is very similar to yield stress fluid, its complex transition between solid and fluid states is not perfectly reversible and especially challenging in terms of pumping, land spreading and drying. To characterize the rheological and textural properties of highly concentrated sludge, a specific methodology based on uniaxial single and cyclic compression tests is developed. Three types of sludge samples (fresh original, fresh premixed and aged original ones) are extruded into cylinders and pressed between two parallel plates using a material testing machine...
February 7, 2017: Water Research
https://www.readbyqxmd.com/read/28213327/visualizing-bpa-by-molecularly-imprinted-ratiometric-fluorescence-sensor-based-on-dual-emission-nanoparticles
#10
Hongzhi Lu, Shoufang Xu
Construction of ratiometric fluorescent probe often involved in tedious multistep preparation or complicated coupling or chemical modification process. The emergence of dual emission fluorescent nanoparticles would simplify the construction process and avoids the tedious chemical coupling. Herein, we reported a facile strategy to prepare ratiometric fluorescence molecularly imprinted sensor based on dual emission nanoparticles (d-NPs) which comprised of carbon dots and gold nanoclusters for detection of Bisphenol A (BPA)...
February 11, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28213323/growth-inhibition-and-efficiency-of-the-antioxidant-system-in-spring-barley-and-common-radish-grown-on-soil-polluted-ionic-liquids-with-iodide-anions
#11
Robert Biczak, Martyna Śnioszek, Arkadiusz Telesiński, Barbara Pawłowska
Ionic liquids (ILs) constitute a huge group of substances that are increasingly common in the commercial use. This situation may lead to the contamination of the soil environment which being the basic of plants vegetation. This paper presents the effect of four ILs with I(-) anion on the growth and development of spring barley (Hordeum vulgare) and common radish (Raphanus sativus L. subvar. radicula Pers) and changes in metabolism of the plants. Seedlings of spring barley and common radish cultivated on soil with increasing ILs concentration exhibited typical phytotoxicity symptoms...
February 14, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28212721/an-exploration-of-the-mechanisms-of-change-following-an-integrated-group-intervention-for-stuttering-as-perceived-by-school-aged-children-who-stutter-cws
#12
Sarah Caughter, Sandra Dunsmuir
PURPOSE: To explore the process of change and role of resilience following an integrated group intervention for children who stutter (CWS). METHOD: Using an exploratory multiple case study design, this research sought to identify the most significant changes perceived by seven participants following therapy, the mechanisms of change, and the role of resilience in the process of change. Quantitative measurements of resilience were combined with qualitative analysis of semi-structured interviews...
March 2017: Journal of Fluency Disorders
https://www.readbyqxmd.com/read/28212644/assessment-of-educational-needs-and-quality-of-life-of-chronic-hepatitis-patients
#13
Ming-Chuan Chen, Hung-Chang Hung, Hsiu-Ju Chang, Sheng-Shun Yang, Wen-Chen Tsai, Shu-Chuan Chang
BACKGROUND: Patient education is crucial in improving the health-related quality of life (HRQOL) of patients. At the same, understanding the concerns and needs of patients is essential in providing appropriate education. This study assessed the educational needs and HRQOL experienced by chronic hepatitis patients. METHODS: We developed structured questionnaires with satisfactory validity and reliability to assess the educational needs of patients. HROQL was measured using a generic Short Form 36 (SF-36) and a liver disease-specific Chronic Liver Disease Questionnaire (CLDQ)...
February 17, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28212389/application-of-calibrated-forceps-for-assessing-mechanical-nociception-with-high-time-resolution-in-mice
#14
Hideki Kashiwadani, Yuichi Kanmura, Tomoyuki Kuwaki
In order to investigate the basic physiological mechanisms of pain and the anti-nociceptive effects of analgesics, development of pain assays in mice is critical due to the advances of genetic manipulation techniques. The von Frey hairs/Semmes-Weinstein monofilaments test (von Frey test) has long been applied to examine mechanical nociception in mice. Though the von Frey test is a well-established and standardized method, it is inappropriate to assess a rapid change in the nociceptive threshold because voluntary resting/sleeping states are necessary to examine the response...
2017: PloS One
https://www.readbyqxmd.com/read/28212312/genome-wide-prediction-of-dna-methylation-using-dna-composition-and-sequence-complexity-in-human
#15
Chengchao Wu, Shixin Yao, Xinghao Li, Chujia Chen, Xuehai Hu
DNA methylation plays a significant role in transcriptional regulation by repressing activity. Change of the DNA methylation level is an important factor affecting the expression of target genes and downstream phenotypes. Because current experimental technologies can only assay a small proportion of CpG sites in the human genome, it is urgent to develop reliable computational models for predicting genome-wide DNA methylation. Here, we proposed a novel algorithm that accurately extracted sequence complexity features (seven features) and developed a support-vector-machine-based prediction model with integration of the reported DNA composition features (trinucleotide frequency and GC content, 65 features) by utilizing the methylation profiles of embryonic stem cells in human...
February 16, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28211843/performance-and-metabolic-demand-of-a-new-repeated-sprint-ability-test-in-basketball-players-does-the-number-of-changes-of-direction-matter
#16
Alessandro M Zagatto, Luca P Ardigò, Fabio A Barbieri, Fabio Milioni, Antonio Dello Iacono, Bruno H F Camargo, Johnny Padulo
This study compared two repeated-sprint ability tests in basketball players. Both tests included 10×30-m sprints, with the difference that the previously validated test (RSA2COD) featured two changes of direction (COD) per sprint, while the experimental test (RSA5COD) featured five CODs per sprint. Tests` performances and metabolic demands were specifically assessed in 20 basketball players. Firstly, RSA5COD test-retest reliability was investigated. Then RSA2COD, RSA5COD sprint times, peak speeds, oxygen uptake (VO2) and post-test blood lactate concentration [La] were measured...
November 5, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28211185/a-comparison-of-goldmann-iii-v-and-spatially-equated-test-stimuli-in-visual-field-testing-the-importance-of-complete-and-partial-spatial-summation
#17
Jack Phu, Sieu K Khuu, Barbara Zangerl, Michael Kalloniatis
PURPOSE: Goldmann size V (GV) test stimuli are less variable with a greater dynamic range and have been proposed for measuring contrast sensitivity instead of size III (GIII). Since GIII and GV operate within partial summation, we hypothesise that actual GV (aGV) thresholds could predict GIII (pGIII) thresholds, facilitating comparisons between actual GIII (aGIII) thresholds with pGIII thresholds derived from smaller GV variances. We test the suitability of GV for detecting visual field (VF) loss in patients with early glaucoma, and examine eccentricity-dependent effects of number and depth of defects...
March 2017: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/28211058/a-feasibility-study-of-a-hybrid-breast-immobilization-system-for-early-breast-cancer-in-proton-beam-therapy
#18
Takeshi Arimura, Takashi Ogino, Takashi Yoshiura, Mitsugi Matsuyama, Naoaki Kondo, Hideki Miyazaki, Akari Sakuragi, Takayuki Ohara, Etsuyo Ogo, Yoshio Hishikawa
PURPOSE: We aimed to develop a new breast-immobilizing system for proton beam therapy (PBT) of early breast cancer (EBC) that would provide the optimum breast shape during the treatment as well as increased fixation reliability by reducing the influence of respiratory movement. METHODS: The breast-immobilizing system (HyBIS; Hybrid Breast-Immobilizing System) consists of a whole body immobilization system (WBIS), position converting device (to change patient position), photo scanning system, breast cup (made using a three-dimensional printer), breast cup fitting apparatus, breast cup holding device (to ensure the breast remains lifted in the supine position), and dedicated stretcher fixed to the WBIS (to carry the patient)...
February 16, 2017: Medical Physics
https://www.readbyqxmd.com/read/28210936/does-obesity-affect-the-non-invasive-measurement-of-cardiac-output-performed-by-electrical-cardiometry-in-children-and-adolescents
#19
Luis Altamirano-Diaz, Eva Welisch, Ralf Rauch, Michael Miller, Teresa Sohee Park, Kambiz Norozi
Electrical cardiometry (EC) is a non-invasive and inexpensive method for hemodynamic assessment and monitoring. However, its feasibility for widespread clinical use, especially for the obese population, has yet to be determined. In this study, we evaluated the agreement and reliability of EC compared to transthoracic Doppler echocardiography (TTE) in normal, overweight, and obese children and adolescents. We measured stroke volume (SV) and cardiac output (CO) of 131 participants using EC and TTE simultaneously...
February 17, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28210480/cross-cultural-psychometric-evaluation-of-the-dutch-mcgill-qol-questionnaire-for-breast-cancer-patients
#20
T De Vrieze, D Coeck, H Verbelen, N Devoogdt, W Tjalma, N Gebruers
AIM OF THE STUDY: Assessing the cross-cultural psychometric properties of the Dutch-MQoL for breast cancer patients. METHODS: 26 patients were recruited at the Antwerp University Hospital. Eligible patients filled in the MQoL on different moments in time in order to evaluate clinimetric properties. To determine the validity; MQoL was correlated to the EORTC QLQ-C30. Internal consistency was analysed using Cronbach's and test-retest reliability was determined by ICC...
December 2016: Facts, Views & Vision in ObGyn
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