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https://www.readbyqxmd.com/read/28346795/understanding-the-emission-impacts-of-hov-to-hot-lane-conversions-experience-from-atlanta-ga
#1
Yanzhi Ann Xu, Haobing Liu, Michael O Rodgers, Angshuman Guin, Michael Hunter, Adnan Sheikh, Randall L Guensler
Converting a congested High Occupancy Vehicle (HOV) lane into a High Occupancy Toll (HOT) lane is a viable option for improving travel time reliability for carpools and buses that use the managed lane. However, the emission impacts of HOV-to-HOT-conversions are not well understood. The lack of emissions impact quantification for HOT conversions creates a policy challenge for agencies making transportation funding choices. The goal of this paper is to evaluate the case study before-and-after changes in vehicle emissions for the Atlanta, GA I-85 HOV/HOT lane conversion project, implemented in October, 2011...
March 27, 2017: Journal of the Air & Waste Management Association
https://www.readbyqxmd.com/read/28346696/do-people-trust-dentists-development-of-the-dentist-trust-scale
#2
Jason M Armfield, Manon Ketting, Sergio Chrisopoulos, Sarah R Baker
BACKGROUND: This study aimed to adapt a measure of trust in physicians generally to trust in dentists and to assess the reliability and validity of the measure. METHODS: Questionnaire data were collected from a simple random sample of 596 Australian adults. The 11-item General Trust in Physicians Scale (Hall et al., 2002) was modified to apply to dentists. RESULTS: The Dentist Trust Scale (DTS) had good internal consistency (Cronbach's alpha = 0...
March 27, 2017: Australian Dental Journal
https://www.readbyqxmd.com/read/28346535/caudwell-xtreme-everest-a-prospective-study-of-the-effects-of-environmental-hypoxia-on-cognitive-functioning
#3
Konstadina Griva, Jan Stygall, Mark H Wilson, Daniel Martin, Denny Levett, Kay Mitchell, Monty Mythen, Hugh E Montgomery, Mike P Grocott, Golnar Aref-Adib, Mark Edsell, Tracie Plant, Chris Imray, Debbie Cooke, Jane Harrington, Maryam Khosravi, Stanton P Newman
BACKGROUND: The neuropsychological consequences of exposure to environmental hypobaric hypoxia (EHH) remain unclear. We thus investigated them in a large group of healthy volunteers who trekked to Mount Everest base camp (5,300 m). METHODS: A neuropsychological (NP) test battery assessing memory, language, attention, and executive function was administered to 198 participants (age 44.5±13.7 years; 60% male). These were studied at baseline (sea level), 3,500 m (Namche Bazaar), 5,300 m (Everest Base Camp) and on return to 1,300 m (Kathmandu) (attrition rate 23...
2017: PloS One
https://www.readbyqxmd.com/read/28345847/five-year-survival-is-not-a-useful-measure-for-cancer-control-in-the-population-an-analysis-based-on-uk-data
#4
Si Qi Li, Xiong Fei Pan, Michael Saheb Kashaf, Qing Ping Xue, Hui Jing Luo, Yan Yan Wang, Ying Wen, Chun Xia Yang
Background: Five-year survival is an important metric for progress in cancer control broadly used both in the cancer literature and by the public. In order to assess its validity and relation to other common metrics, we analyzed the relationship between 5-year survival, incidence and mortality using publicly available cancer registry data from England and Wales. Methods: Five-year survival, incidence and mortality data were obtained from the online database of a registered charity, Cancer Research UK. We extracted sex-specific age-standardized mortality, incidence, and 5-year survivalfor16 types of cancer over the period from 1976 to 1995...
February 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28345508/use-of-a-novel-portable-led-based-capillary-refill-time-simulator-within-a-disaster-triage-context
#5
Todd P Chang, Genevieve Santillanes, Ilene Claudius, Phung K Pham, James Koved, John Cheyne, Marianne Gausche-Hill, Amy H Kaji, Saranya Srinivasan, J Joelle Donofrio, Cynthia Bir
Introduction A simple, portable capillary refill time (CRT) simulator is not commercially available. This device would be useful in mass-casualty simulations with multiple volunteers or mannequins depicting a variety of clinical findings and CRTs. The objective of this study was to develop and evaluate a prototype CRT simulator in a disaster simulation context. METHODS: A CRT prototype simulator was developed by embedding a pressure-sensitive piezo crystal, and a single red light-emitting diode (LED) light was embedded, within a flesh-toned resin...
March 27, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28345503/physical-fitness-and-shapes-of-subcortical-brain-structures-in-children
#6
Francisco B Ortega, Daniel Campos, Cristina Cadenas-Sanchez, Signe Altmäe, Cristina Martínez-Zaldívar, Miguel Martín-Matillas, Andrés Catena, Cristina Campoy
A few studies have recently reported that higher cardiorespiratory fitness is associated with higher volumes of subcortical brain structures in children. It is, however, unknown how different fitness measures relate to shapes of subcortical brain nuclei. We aimed to examine the association of the main health-related physical fitness components with shapes of subcortical brain structures in a sample of forty-four Spanish children aged 9·7 (sd 0·2) years from the NUtraceuticals for a HEALthier life project...
March 27, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28345139/utility-of-%C3%AE-hcg-monitoring-in-the-follow-up-of-medical-management-of-miscarriage
#7
Scott G Petersen, Anneliese R Perkins, Kristen S Gibbons, Julia I Bertolone, Kassam Mahomed
OBJECTIVE: To evaluate the percentage change in total βeta-unit human chorionic gonadotropin (βhCG) levels (%ΔβhCG) in the prediction of treatment outcomes following intravaginal misoprostol for missed miscarriage before 13 weeks. METHODS: A secondary analysis of a randomised controlled study of medical management of miscarriage was performed. Total βhCG levels were collected before misoprostol (baseline) and after a planned seven day interval (follow-up), when a transvaginal ultrasound (TVUS) reported a gestational sac as present or not...
March 27, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28345033/improved-estimates-of-ocean-heat-content-from-1960-to-2015
#8
Lijing Cheng, Kevin E Trenberth, John Fasullo, Tim Boyer, John Abraham, Jiang Zhu
Earth's energy imbalance (EEI) drives the ongoing global warming and can best be assessed across the historical record (that is, since 1960) from ocean heat content (OHC) changes. An accurate assessment of OHC is a challenge, mainly because of insufficient and irregular data coverage. We provide updated OHC estimates with the goal of minimizing associated sampling error. We performed a subsample test, in which subsets of data during the data-rich Argo era are colocated with locations of earlier ocean observations, to quantify this error...
March 2017: Science Advances
https://www.readbyqxmd.com/read/28344464/the-biomechanics-of-standing-start-and-initial-acceleration-reliability-of-the-key-determining-kinematics
#9
Regan J Standing, Peter S Maulder
The reliability of the key determining kinematic variables associated with short sprint performance provide insight into how and why movement may vary between individual trials. Currently, literature surrounding these determinants is scarce when investigating the first three strides of a sprint. The purpose of this study was to investigate the reliability of sprint acceleration and the key kinematic determinants involved during the first three steps of the movement. The aim was to use a practical method of kinematic analysis to help explain why changes may occur in sprint performance via the use of correlative statistics and to provide reference values for intervention research to make conclusions about their change scores...
March 2017: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/28343983/comprehensive-cell-surface-protein-profiling-identifies-specific-markers-of-human-naive-and-primed-pluripotent-states
#10
Amanda J Collier, Sarita P Panula, John Paul Schell, Peter Chovanec, Alvaro Plaza Reyes, Sophie Petropoulos, Anne E Corcoran, Rachael Walker, Iyadh Douagi, Fredrik Lanner, Peter J Rugg-Gunn
Human pluripotent stem cells (PSCs) exist in naive and primed states and provide important models to investigate the earliest stages of human development. Naive cells can be obtained through primed-to-naive resetting, but there are no reliable methods to prospectively isolate unmodified naive cells during this process. Here we report comprehensive profiling of cell surface proteins by flow cytometry in naive and primed human PSCs. Several naive-specific, but not primed-specific, proteins were also expressed by pluripotent cells in the human preimplantation embryo...
March 21, 2017: Cell Stem Cell
https://www.readbyqxmd.com/read/28343619/translation-and-validation-of-neck-bournemouth-questionnaire-to-brazilian-portuguese
#11
Danilo Harudy Kamonseki, Luísa Cedin, Jaqueline Tavares-Preto, Beatriz de Oliveira Peixoto, Sandro Rostelato-Ferreira
OBJECTIVE: To translate the Neck Bournemouth Questionnaire to Brazilian Portuguese, cross-culturally adapt, and to verify its validity and its reliability. METHODS: The development of the Brazilian version of Neck Bournemouth Questionnaire (Brazil-NBQ) was based on the guideline proposed by Guillemin. The applied process consisted of translation, back-translation, committee review and pre-test. Sixty-one volunteers presenting neck pain participated in this study...
March 2017: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/28343292/psychometric-validation-of-the-heart-failure-caregiver-questionnaire-hf-cq-%C3%A2
#12
Anna Strömberg, Nicola Bonner, Laura Grant, Bryan Bennett, Misook L Chung, Tiny Jaarsma, Marie Louise Luttik, Eldrin F Lewis, Frederico Calado, Celine Deschaseaux
BACKGROUND: The Heart Failure Caregiver Questionnaire (HF-CQ(®)) was developed to assess subjective outcomes of heart failure caregivers. The HF-CQ(®) comprises 21 questions on three domains, namely physical, emotional/psychological and lifestyle. The objective of this study was to evaluate the psychometric properties of the HF-CQ(®). METHODS: Patients (n = 150) with heart failure and their primary caregivers (n = 150) were recruited from 11 sites in USA...
March 25, 2017: Patient
https://www.readbyqxmd.com/read/28343049/stabilisation-of-spent-mushroom-substrate-for-application-as-a-plant-growth-promoting-organic-amendment
#13
Fabiana S Paula, Enrico Tatti, Florence Abram, Jude Wilson, Vincent O'Flaherty
Over three million tonnes of spent mushroom substrate (SMS) are produced in Europe every year as a by-product of the cultivation of Agaricus bisporus. The management of SMS has become an increasing challenge for the mushroom production industry, and finding environmentally and economically sustainable solutions for this organic residue is, therefore, highly desirable. Due to its physical properties and nutrient content, SMS has great potential to be employed in agricultural and horticultural sectors, and further contribute to reduce the use of non-renewable resources, such as peat...
March 23, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28342698/targeted-exome-sequencing-and-chromosomal-microarray-for-the-molecular-diagnosis-of-nevoid-basal-cell-carcinoma-syndrome
#14
Yoshihiro Matsudate, Takuya Naruto, Yumiko Hayashi, Mitsuyoshi Minami, Mikiko Tohyama, Kenji Yokota, Daisuke Yamada, Issei Imoto, Yoshiaki Kubo
BACKGROUND: Nevoid basal cell carcinoma syndrome (NBCCS) is an autosomal dominant disorder mainly caused by heterozygous mutations of PTCH1. In addition to characteristic clinical features, detection of a mutation in causative genes is reliable for the diagnosis of NBCCS; however, no mutations have been identified in some patients using conventional methods. OBJECTIVE: To improve the method for the molecular diagnosis of NBCCS. METHODS: We performed targeted exome sequencing (TES) analysis using a multi-gene panel, including PTCH1, PTCH2, SUFU, and other sonic hedgehog signaling pathway-related genes, based on next-generation sequencing (NGS) technology in 8 cases in whom possible causative mutations were not detected by previously performed conventional analysis and 2 recent cases of NBCCS...
March 11, 2017: Journal of Dermatological Science
https://www.readbyqxmd.com/read/28342558/high-intensity-focused-ultrasound-as-first-line-treatment-in-patients-with-chronic-angle-closure-glaucoma-at-risk-for-malignant-glaucoma
#15
M Graber, Z Khoueir, A Beauchet, N Benhatchi, S Hammoud, Y Lachkar
PURPOSE: Evaluation of high intensity focused ultrasound (HIFU) transscleral cyclocoagulation as an alternative to trabeculectomy in the treatment of refractory chronic angle closure glaucoma (CACG). METHODS: This prospective one armed single center pilot study was conducted on patients with medically uncontrolled CACG who underwent high intensity focused ultrasound (HIFU) cyclocoagulation as first line surgical treatment, using the Eye-OP1 HIFU device (Eyetechcare-Rillieux-la-Pape, France) driven by ultrasound biomicroscopic (UBM) ciliary body localization...
March 22, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28342260/neural-decoding-of-visual-stimuli-varies-with-fluctuations-in-global-network-efficiency
#16
Luca Cocchi, Zhengyi Yang, Andrew Zalesky, Johannes Stelzer, Luke J Hearne, Leonardo L Gollo, Jason B Mattingley
Functional magnetic resonance imaging (fMRI) studies have shown that neural activity fluctuates spontaneously between different states of global synchronization over a timescale of several seconds. Such fluctuations generate transient states of high and low correlation across distributed cortical areas. It has been hypothesized that such fluctuations in global efficiency might alter patterns of activity in local neuronal populations elicited by changes in incoming sensory stimuli. To test this prediction, we used a linear decoder to discriminate patterns of neural activity elicited by face and motion stimuli presented periodically while participants underwent time-resolved fMRI...
March 25, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28342236/resolving-protein-structure-function-binding-site-relationships-from-a-binding-site-similarity-network-perspective
#17
Richa Mudgal, Narayanaswamy Srinivasan, Nagasuma Chandra
Functional annotation is seldom straightforward with complexities arising due to functional divergence in protein families or functional convergence between non-homologous protein families, leading to mis-annotations. An enzyme may contain multiple domains and not all domains may be involved in a given function, adding to the complexity in function annotation. To address this, we use binding site information from bound cognate ligands and catalytic residues, since it can help in resolving fold-function relationships at a finer level and with higher confidence...
March 25, 2017: Proteins
https://www.readbyqxmd.com/read/28342225/japanese-version-of-the-family-dermatology-life-quality-index-translation-and-validation
#18
Yuko Higaki, Masaru Tanaka, Yuko Futei, Toshiko Kamo, Mohammad Khurshid Azam Basra, Andrew Yule Finlay
Skin conditions affect the quality of life (QoL) of patients and their family. To assess family members' QoL, a questionnaire uniquely designed for family members is necessary. We translated the Family Dermatology Life Quality Index (FDLQI), originally created and validated by Basra et al., into Japanese, and evaluated its reliability and validity. For psychometric evaluations, 150 dermatology patients and their family members were included. The Japanese version of the FDLQI showed high test-retest reliability (intraclass correlation coefficient = 0...
March 24, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28341993/a-method-for-preparing-silver-nanoparticle-suspensions-in-bulk-for-ecotoxicity-testing-and-ecological-risk-assessment
#19
Jonathan D Martin, Lena Telgmann, Chris D Metcalfe
Methods are needed to prepare stable suspensions of engineered nanoparticles in aqueous matrixes for ecotoxicity testing and ecological risk assessments. We developed a novel method of preparing large volumes of silver nanoparticles (AgNP) in suspension using a commercially available rotor-stator dispersion mill. AgNP in powder form (PVP capped, 30-50 nm) was suspended in deionized water and natural lake water at 1 g/L and the addition of 0.025% (w/v) gum arabic (GA) increased stability over 2 weeks after preparation...
March 24, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28341468/cause-and-predictability-for-the-severe-haze-pollution-in-downtown-beijing-in-november-december-2015
#20
Ziyin Zhang, Daoyi Gong, Rui Mao, Seong-Joong Kim, Jing Xu, Xiujuan Zhao, Zhiqiang Ma
Based on the hourly PM2.5 concentrations, meteorological variable records and ERA-Interim reanalysis data, a series of diagnostic analyses were conducted to explore the possible meteorological causes for the severe haze pollution that occurred in Beijing in November-December 2015. Using the online-coupled WRF-Chem model and GFS data, the predictability of hourly and daily PM2.5 concentrations was evaluated. The results showed that, in the context of pollutant emission, the severe haze pollution in downtown Beijing in November-December 2015 was primarily attributed to anomalous local meteorological conditions, which were caused and strengthened by anomalous large-scale atmospheric circulations...
March 21, 2017: Science of the Total Environment
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