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https://www.readbyqxmd.com/read/28944730/optimization-of-medication-use-at-accountable-care-organizations
#1
Chrisanne Wilks, Erik Krisle, Kimberly Westrich, Kristina Lunner, David Muhlestein, Robert Dubois
BACKGROUND: Optimized medication use involves the effective use of medications for better outcomes, improved patient experience, and lower costs. Few studies systematically gather data on the actions accountable care organizations (ACOs) have taken to optimize medication use. OBJECTIVES: To (a) assess how ACOs optimize medication use; (b) establish an association between efforts to optimize medication use and achievement on financial and quality metrics; (c) identify organizational factors that correlate with optimized medication use; and (d) identify barriers to optimized medication use...
October 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28944728/performance-based-risk-sharing-arrangements-u-s-payer-experience
#2
Joseph A Goble, Brian Ung, Sascha van Boemmel-Wegmann, Robert P Navarro, Andrew Parece
BACKGROUND: As a result of global concern about rising drug costs, many U.S. payers and European agencies such as the National Health Service have partnered with pharmaceutical companies in performance-based risk-sharing arrangements (PBRSAs) by which manufacturers share financial risk with health care purchasing entities and authorities. However, PBRSAs present many administrative and legal challenges that have minimized successful contract experiences in the United States. OBJECTIVE: To (a) identify drug and disease characteristics and contract components that contribute to successful PBRSA experiences and the primary barriers to PBRSA execution and (b) explore solutions to facilitate contract negotiation and execution...
October 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28944687/heavy-drinking-among-individuals-with-hiv-who-drinks-despite-knowledge-of-the-risk
#3
Jennifer C Elliott, Malka Stohl, Deborah S Hasin
Heavy drinking can cause medical problems for individuals with HIV, and drinking despite medical contraindications indicates problem use. However, little is known about which individuals with HIV drink despite knowledge of health problems. This study utilizes two subsamples of individuals with HIV from the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III): those reporting at least one drink (a) in their lifetime (n = 205) or (b) in the past year (n = 166). Participants reported on drinking despite health problems and psychopathology in the past year and in their lifetime, and family history of alcohol problems...
September 25, 2017: AIDS Care
https://www.readbyqxmd.com/read/28942288/differences-in-behavioral-health-disorders-and-unmet-treatment-needs-between-medical-marijuana-users-and-recreational-marijuana-users-results-from-a-national-adult-sample
#4
Ji-Yeun Park, Li-Tzy Wu
BACKGROUND: Available data suggest that medical marijuana users may have more mental health problems than recreational marijuana users. There is limited information about differences in behavioral health disorders and unmet treatment needs between medical and recreational marijuana users. METHODS: We compared past-year prevalence of behavioral health disorders and unmet treatment needs across three marijuana subgroups (recreational use only, medical use only, and both)...
September 14, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28941090/estimating-treatment-coverage-for-people-with-substance-use-disorders-an-analysis-of-data-from-the-world-mental-health-surveys
#5
Louisa Degenhardt, Meyer Glantz, Sara Evans-Lacko, Ekaterina Sadikova, Nancy Sampson, Graham Thornicroft, Sergio Aguilar-Gaxiola, Ali Al-Hamzawi, Jordi Alonso, Laura Helena Andrade, Ronny Bruffaerts, Brendan Bunting, Evelyn J Bromet, José Miguel Caldas de Almeida, Giovanni de Girolamo, Silvia Florescu, Oye Gureje, Josep Maria Haro, Yueqin Huang, Aimee Karam, Elie G Karam, Andrzej Kiejna, Sing Lee, Jean-Pierre Lepine, Daphna Levinson, Maria Elena Medina-Mora, Yosikazu Nakamura, Fernando Navarro-Mateu, Beth-Ellen Pennell, José Posada-Villa, Kate Scott, Dan J Stein, Margreet Ten Have, Yolanda Torres, Zahari Zarkov, Somnath Chatterji, Ronald C Kessler
Substance use is a major cause of disability globally. This has been recognized in the recent United Nations Sustainable Development Goals (SDGs), in which treatment coverage for substance use disorders is identified as one of the indicators. There have been no estimates of this treatment coverage cross-nationally, making it difficult to know what is the baseline for that SDG target. Here we report data from the World Health Organization (WHO)'s World Mental Health Surveys (WMHS), based on representative community household surveys in 26 countries...
October 2017: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
https://www.readbyqxmd.com/read/28941007/leveraging-population-based-clinical-quantitative-phenotyping-for-drug-repositioning
#6
Adam S Brown, Danielle Rasooly, Chirag J Patel
Computational drug repositioning methods can scalably nominate approved drugs for new diseases, with reduced risk of unforeseen side effects. The majority of methods eschew individual-level phenotypes despite the promise of biomarker-driven repositioning. In this study, we propose a framework for discovering serendipitous interactions between drugs and routine clinical phenotypes in cross-sectional observational studies. Key to our strategy is the use of a healthy and non-diabetic population derived from the National Health and Nutrition Examination Survey, mitigating risk for confounding by indication...
September 22, 2017: CPT: Pharmacometrics & Systems Pharmacology
https://www.readbyqxmd.com/read/28935385/digital-self-harm-among-adolescents
#7
Justin W Patchin, Sameer Hinduja
PURPOSE: Despite increased media and scholarly attention to digital forms of aggression directed toward adolescents by their peers (e.g., cyberbullying), very little research has explored digital aggression directed toward oneself. "Digital self-harm" is the anonymous online posting, sending, or otherwise sharing of hurtful content about oneself. The current study examined the extent of digital self-harm among adolescents. METHODS: Survey data were obtained in 2016 from a nationally representative sample of 5,593 American middle and high school students (12-17 years old)...
September 18, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28930065/trends-in-perceived-access-to-marijuana-among-adolescents-in-the-united-states-2002-2015
#8
Christopher P Salas-Wright, Sehun Oh, Trenette Clark Goings, Michael G Vaughn
OBJECTIVE: There is concern that changes in marijuana-related policy and public opinion may lead to increased access to marijuana among young people in the United States. However, little research has been conducted on changes in youth's perceptions of marijuana access, and studies have yet to systematically examine trends in perceived access across key sociodemographic and externalizing behavioral subgroups. METHOD: Using population-based data collected between 2002 and 2015 as part of the National Survey on Drug Use and Health, we examined trends in perceived marijuana access among non-Hispanic White, African American, and Hispanic adolescents (ages 12-17, n = 221,412)...
September 2017: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/28927405/the-use-of-respondent-driven-sampling-to-assess-malaria-knowledge-treatment-seeking-behaviours-and-preventive-practices-among-mobile-and-migrant-populations-in-a-setting-of-artemisinin-resistance-in-western-cambodia
#9
Po Ly, Julie Thwing, Colleen McGinn, Cesia E Quintero, Narann Top-Samphor, Najibullah Habib, Jack S Richards, Sara E Canavati, Seshu Babu Vinjamuri, Chea Nguon
BACKGROUND: Multi-drug-resistant Plasmodium falciparum threatens malaria elimination efforts in Cambodia and the Greater Mekong Subregion (GMS). Malaria burden in the GMS is higher among certain high-risk demographic groups in Cambodia, especially among migrant and mobile populations (MMPs). This respondent driven sampling (RDS) study was conducted in order to determine malaria knowledge, treatment-seeking behaviours and preventive practices among two MMP groups in Western Cambodia. METHODS: An RDS survey of MMPs was implemented in four purposively-selected communes along the Thai-Cambodia border; two in Veal Veang District and two in Pailin Province, chosen due to their sizeable MMP groups, their convenience of access, and their proximity to Thailand, which allowed for comparison with RDS studies in Thailand...
September 19, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28921407/combat-exposure-emotional-and-physical-role-limitations-and-substance-use-among-male-united-states-army-reserve-and-national-guard-soldiers
#10
R A Hoopsick, B M Vest, D L Homish, G G Homish
PURPOSE: Combat-exposed soldiers are at an increased risk for health problems that diminish quality of life (QOL) and substance use. We explored the cross-sectional associations between combat exposure and two measures of QOL, and the effect of substance use on those associations. METHODS: Data are from the baseline wave of Operation: SAFETY, an ongoing survey-based study of United States Army Reserve/National Guard (USAR/NG) soldiers and their partners. Our sample consisted of male USAR/NG soldiers with a history of deployment (N = 248)...
September 18, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28919116/global-regional-and-national-age-sex-specific-mortality-for-264-causes-of-death-1980-2016-a-systematic-analysis-for-the-global-burden-of-disease-study-2016
#11
(no author information available yet)
BACKGROUND: Monitoring levels and trends in premature mortality is crucial to understanding how societies can address prominent sources of early death. The Global Burden of Disease 2016 Study (GBD 2016) provides a comprehensive assessment of cause-specific mortality for 264 causes in 195 locations from 1980 to 2016. This assessment includes evaluation of the expected epidemiological transition with changes in development and where local patterns deviate from these trends. METHODS: We estimated cause-specific deaths and years of life lost (YLLs) by age, sex, geography, and year...
September 16, 2017: Lancet
https://www.readbyqxmd.com/read/28918239/cigarette-smoking-quit-rates-among-adults-with-and-without-alcohol-use-disorders-and-heavy-alcohol-use-2002-2015-a-representative-sample-of-the-united-states-population
#12
Andrea H Weinberger, Misato Gbedemah, Renee D Goodwin
BACKGROUND: While the overall smoking quit rate has increased over time, it is not known whether the quit rate has also increased among persons with alcohol use disorders (AUDs) or heavy alcohol use (HAU). The current study examined quit rates among adults with and without AUDs and HAU over a 12-year period in a representative sample of US adults. METHODS: Data were drawn from the National Household Survey on Drug Use, an annual cross-sectional study of US persons...
August 5, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28915227/dietary-sodium-intake-among-us-adults-with-hypertension-1999-2012
#13
Elena V Dolmatova, Kasra Moazzami, Sameer Bansilal
OBJECTIVE: Excess sodium consumption has strong links with hypertension and cardiovascular disease with Food and Drug Association calling to limit sodium intake. However, little is known regarding the trends of sodium intake among hypertensive patients in the United States. METHODS: Data from The National Health and Nutrition Examination Survey (1999-2012) were used to identify adults older than 20 years with self-reported hypertension. Sodium intake was measured through 24-h dietary recall...
September 14, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28911662/pharmacokinetic-interactions-of-herbal-medicines-for-the-treatment-of-chronic-hepatitis
#14
REVIEW
Tun-Pin Hsueh, Wan-Ling Lin, Tung-Hu Tsai
Chronic liver disease is a serious global health problem, and an increasing number of patients are seeking alternative medicines or complementary treatment. Herbal medicines account for 16.8% of patients with chronic liver disease who use complementary and alternative therapies. A survey of the National Health Insurance Research Database in Taiwan reported that Long-Dan-Xie-Gan-Tang, Jia-Wei-Xia-Yao-San, and Xiao-Chai-Hu-Tang (Sho-saiko-to) were the most frequent formula prescriptions for chronic hepatitis used by traditional Chinese medicine physicians...
April 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28910259/estimation-of-smoking-prevalence-in-canada-implications-of-survey-characteristics-in-the-cchs-and-ctums-ctads
#15
Thierry Gagné
One of the main enterprises associated with tobacco control is surveillance, that is, to measure and follow over time the extent of smoking among the Canadian population. While surveillance systems have been in place for more than 50 years, knowing the exact prevalence of smoking in Canada continues to be a complex matter and understanding its estimation requires a critical appreciation of our national surveys' idiosyncrasies. This commentary describes the two Statistics Canada surveys that are most commonly used to examine smoking prevalence in this country: the Canadian Community Health Survey (CCHS) and the Canadian Tobacco, Alcohol and Drugs Survey (CTADS)...
September 14, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/28898808/associations-between-statewide-prescription-drug-monitoring-program-pdmp-requirement-and-physician-patterns-of-prescribing-opioid-analgesics-for-patients-with-non-cancer-chronic-pain
#16
Hsien-Chang Lin, Zhi Wang, Carol Boyd, Linda Simoni-Wastila, Anne Buu
OBJECTIVE: State-level prescription drug monitoring programs (PDMPs) have been implemented in most states. PDMPs enable registered prescribers to obtain real-time information on patients' prescription history to reduce non-medical use of controlled drugs. This study examined whether PDMP implementation and different levels of PDMP requirements were associated with physicians' patterns of prescribing opioid analgesics for patients with non-cancer chronic pain. METHODS: This is a secondary analysis study using cross-sectional national data...
September 5, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28898565/the-projected-burden-of-osteoarthritis-and-rheumatoid-arthritis-in-australia-a-population-level-analysis
#17
Ilana N Ackerman, Clare Pratt, Alexandra Gorelik, Danny Liew
OBJECTIVE: To forecast the prevalence and direct healthcare costs of osteoarthritis (OA) and rheumatoid arthritis (RA) in Australia to the year 2030. METHODS: An epidemiological model of the Australian population was developed. Data on the national prevalence of OA and RA were obtained from the Australian Bureau of Statistics (ABS) 2014-2015 National Health Survey. Future prevalence was estimated using ABS population projections for 2020, 2025 and 2030. Available government data on direct healthcare expenditure for OA and RA were modelled to forecast costs (in AUD) for the years 2020, 2025 and 2030, from the perspective of the Australian public healthcare system...
September 12, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28895798/nonmedical-opioid-use-in-relation-to-recency-of-heroin-use-in-a-nationally-representative-sample-of-adults-in-the-united-states
#18
Joseph J Palamar, Jenni A Shearston
Nonmedical opioid use has been linked to lifetime heroin use; however, research is needed to examine associations between nonmedical opioid use and current or recent heroin use, as current users appear to be at highest risk for harm. Data were from a nationally representative sample of non-institutionalized adults (age 18-64) in households participating in the National Survey of Drug Use and Health who reported lifetime heroin use (2005-2014, N = 7,111). We examined associations between frequency and recency of nonmedical opioid use and recency of heroin use...
September 12, 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28890020/the-national-cost-of-asthma-among-school-aged-children-in-the-united%C3%A2-states
#19
Patrick W Sullivan, Vahram Ghushchyan, Prakash Navaratnam, Howard S Friedman, Abhishek Kavati, Benjamin Ortiz, Bob Lanier
BACKGROUND: Recent research has quantified the national health care resource use (HCRU) and health care expenditure (HCE) burden associated with adult asthma; however, estimates specific to school-aged children are more than 2 decades old. OBJECTIVE: To estimate the national HCRU and HCEs attributable to asthma among school-aged children in the United States. METHODS: This was a cross-sectional retrospective analysis of school-aged children (aged 6-17 years) in the nationally representative 2007-2013 Medical Expenditure Panel Survey...
September 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28883985/local-stakeholders-perceptions-of-community-sensitization-for-school-based-deworming-programme-in-kenya
#20
D W Njomo, J Masaku, F Mwende, G Odhiambo, R Musuva, E Matey, I G Thuita, J H Kihara
BACKGROUND: In Kenya, the National School-Based Deworming Programme (NSBDP) for soil-transmitted helminthes and schistosomiasis in prioritized areas has been going on since the year 2012. By the year 2013 over 6 million School Age Children (SAC) had been treated. A community sensitization supplement containing key messages and answers to frequently asked questions was developed as a guiding tool. Awareness creation methods used include county sensitization meetings, stakeholder forums, town criers and posters...
2017: Tropical Diseases, Travel Medicine and Vaccines
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