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https://www.readbyqxmd.com/read/29027307/transient-amniotic-fluid-leakage-after-fetoscopic-laser-photocoagulation-for-twin-twin-transfusion-syndrome
#1
Shiyo Ota, Keisuke Ishii, Hiroshi Kawamura, Aki Mabuchi, Ryo Yamamoto, Shusaku Hayashi, Takeshi Kanagawa, Nobuaki Mitsuda
AIM: Iatrogenic premature rupture of membrane (PROM) is one of the major complications related to fetoscopic laser photocoagulation (FLP) for twin-twin transfusion syndrome (TTTS). However, amniotic fluid leakage (AFL) sometimes spontaneously disappears. This study evaluated the incidence and clinical characteristics of transient AFL after FLP. METHODS: We retrospectively reviewed pregnancies that underwent FLP for TTTS at a single center. Patients with apparent AFL within 2 weeks after FLP were divided into two groups: transient AFL, defined by the disappearance of fluid leakage within a week; and PROM, if AFL persisted continuously for more than a week or premature birth occurred, including miscarriage, within a week of the first symptom of AFL...
October 13, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29026569/sudden-maternal-hypoxemia-during-elective-cesarean-section-in-a-woman-with-placenta-previa
#2
Takeshi Umazume, Satoshi Hayasaka, Fumi Kato, Satoshi Ishikawa, Mamoru Morikawa, Hisanori Minakami
There have been no reports regarding imaging-documented bronchospasm in patients with amniotic fluid embolism (AFE). In a woman with scheduled cesarean section for placenta previa, transient bronchospasm and pulmonary hypertension were documented explaining a sudden drop in SpO2. Mild AFE was the most likely diagnosis in this patient.
October 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/29020827/the-frequency-and-clinical-significance-of-intra-amniotic-inflammation-in-twin-pregnancies-with-preterm-labor-and-intact-membranes
#3
Kyung Joon Oh, Joon-Seok Hong, Roberto Romero, Bo Hyun Yoon
OBJECTIVE: The objective of this study is to evaluate the frequency and clinical significance of intra-amniotic inflammation in twin pregnancies with preterm labor and intact membranes. STUDY DESIGN: Amniotic fluid (AF) was retrieved from both sacs in 90 twin gestations with preterm labor and intact membranes (gestational age between 20 and 34 6/7 weeks). Preterm labor was defined as the presence of painful regular uterine contractions, with a frequency of at least 2 every 10 min, requiring hospitalization...
October 11, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29020816/predictors-of-adverse-perinatal-outcomes-in-intrahepatic-cholestasis-of-pregnancy-with-dichorionic-diamniotic-twin-pregnancies
#4
Youwen Mei, Lan Gao, Yonghong Lin, Dan Luo, Xine Zhou, Li He
OBJECTIVE: The aim of our study was to investigate the predictors of adverse perinatal outcomes in intrahepatic cholestasis of pregnancy (ICP) with dichorionic diamniotic (DCDA) twin pregnancies. METHODS: This study was a retrospective study of women diagnosed with ICP and DCDA twin pregnancies in Chengdu's women and children's central hospital. These patients were subdivided into mild and severe ICP groups according to total bile acid (TBA) level. The clinical characteristics and perinatal outcomes were collected and compared between the two groups...
October 11, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29020781/-the-finding-of-isolated-oligohydramnios-after-37th-week-of%C3%A2-gestation-and-its-association-with-perinatal-outcome
#5
J Hederlingová, M Redecha, J Záhumenský
OBJECTIVE: The objective of this study is to determinate the influence of oligohydramnios on perinatal outcome in term pregnancies. DESIGN: Retrospective case-control study. SETTING: II. Gynecologic Obstetrics Department, Comenius University, Bratislava. METHODS: Authors analysed a group of 372 single pregnancies after completed 37th week of gestation in years 2011 to 2015 with sonographic diagnosis of isolated oligohydramnios...
2017: Ceská Gynekologie
https://www.readbyqxmd.com/read/29016591/caesarean-section-during-second-stage-of-labor-in-a-tertiary-centre
#6
Padma Gurung, Sameer Malla, Sushma Lama, Anagha Malla, Alka Singh
BACKGROUND: There is an alarming rise in caesarean section leading to increased adverse outcomes for both the mother and fetus when compared with vaginal delivery. Within this increasing caesarean section rate, there is a concerning increase in the rate of second stage caesarean section. This study highlight the feto-maternal outcome of caesarean section in second stage of labour. METHODS: This was a retrospective cohort review of all women with a singleton, cephalic fetus at term delivered by caesarean section in the second stage of labor between April 1, 2013 and March 30, 2017 at Patan Academy of Health Sciences...
September 8, 2017: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/28990592/maternal-and-fetal-genetic-contribution-to-gestational-weight-gain
#7
N M Warrington, R Richmond, B Fenstra, R Myhre, R Gaillard, L Paternoster, C A Wang, R N Beaumont, S Das, M Murcia, S J Barton, A Espinosa, E Thiering, M Atalay, N Pitkänen, I Ntalla, A E Jonsson, R Freathy, V Karhunen, C M T Tiesler, C Allard, A Crawford, S M Ring, M Melbye, P Magnus, F Rivadeneira, L Skotte, T Hansen, J Marsh, M Guxens, J W Holloway, H Grallert, V W V Jaddoe, W L Lowe, T Roumeliotaki, A T Hattersley, V Lindi, K Pahkala, K Panoutsopoulou, M Standl, C Flexeder, L Bouchard, E A Nohr, L S Marina, M Kogevinas, H Niinikoski, G Dedoussis, J Heinrich, R M Reynolds, T Lakka, E Zeggini, O T Raitakari, L Chatzi, H M Inskip, M Bustamante, M-F Hivert, M-R Jarvelin, T I A Sørensen, C Pennell, J F Felix, B Jacobsson, F Geller, D M Evans, D A Lawlor
BACKGROUND: Clinical recommendations to limit gestational weight gain (GWG) imply high GWG is causally related to adverse outcomes in mother or offspring, but GWG is the sum of several inter-related complex phenotypes (maternal fat deposition and vascular expansion, placenta, amniotic fluid and fetal growth). Understanding the genetic contribution to GWG could help clarify the potential effect of its different components on maternal and offspring health. Here we explore the genetic contribution to total, early and late GWG...
October 9, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28988880/gender-proteomics-ii-which-proteins-in-sexual-organs
#8
Elisabetta Gianazza, Ingrid Miller, Uliano Guerrini, Luca Palazzolo, Chiara Parravicini, Ivano Eberini
In continuity with the review dealing with differences by gender in non-sexual organs [1], this review collects data on the proteomes of the sexual organs as involved in human reproduction, under both physiological and pathological conditions. It also collects data on the tissue structures and biological fluids typical of pregnancy, such as placenta and amniotic fluid, as well as what may be tested on preimplantation embryos during medically assisted reproduction. The review includes as well mention to all fluids and secretions connected with sex organs and/or reproduction, including sperm and milk, to exemplify two distinctive items in male and female physiology...
October 5, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/28983905/right-heart-masses-demonstrated-by-echocardiography-in-a-patient-with-amniotic-fluid-embolism-during-labour
#9
K H Maack, K Munk, K Dahl, H H Jørgensen, A Christiansen, R B Helmig
No abstract text is available yet for this article.
October 5, 2017: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/28982681/early-neonatal-loss-of-inhibitory-synaptic-input-to-the-spinal-motor-neurons-confers-spina-bifida-like-leg-dysfunction-in-a-chicken-model
#10
Md Sakirul Islam Khan, Hiroaki Nabeka, Farzana Islam, Tetsuya Shimokawa, Shouichiro Saito, Xuan Li, Soichiro Kawabe, Fumihiko Hamada, Tetsuya Tachibana, Seiji Matsuda
Spina bifida aperta (SBA), one of the most common congenital malformations, causes lifelong neurological complications particularly in terms of motor dysfunction. Fetuses with SBA exhibit voluntary leg movements in utero and during early neonatal life but these disappear within the first few weeks after birth. However, the pathophysiological sequence underlying such motor dysfunction remains unclear. Additionally, because important insights have yet to be obtained from human cases, an appropriate animal model is essential...
October 5, 2017: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/28982475/secretome-derived-from-different-cell-lines-in-bovine-embryo-production-in-vitro
#11
C Perrini, P Esposti, F Cremonesi, A Lange Consiglio
The present study investigated the effects of conditioned medium (CM), composed of microvesicles (MVs) and soluble factors present in the supernatant (SN), of bovine endometrial and amniotic cells on embryo quality and rate of blastocyst production. Presumptive zygotes were randomly assigned on Days 1, 3 and 5 after fertilisation to synthetic oviducal fluid with amino acids (SOFaa; control) or to SOFaa supplemented with either 20% endometrial or amniotic CM, 20% SN or 100×106MVsmL-1. Embryos were evaluated on Day 7...
October 6, 2017: Reproduction, Fertility, and Development
https://www.readbyqxmd.com/read/28981921/-mutational-analysis-and-prenatal-diagnosis-in-a-family-affected-with-hypophosphatemic-rickets
#12
Zhaotang Luan, Huanzheng Li, Lin Hu, Chong Chen, Xueqin Xu, Yanbao Xiang, Shaohua Tang
OBJECTIVE: To explore the clinical characteristics and genetic mutation in a family affected with hypophosphatemic rickets. METHODS: Whole exome sequencing (WES) was used to screen potential mutations in genomic DNA extracted from peripheral venous blood sample from the proband. Suspected mutation was confirmed with Sanger sequencing. Amniotic fluid was sampled from the proband for prenatal diagnosis. Potential maternal contamination was excluded by analysis of short tandem repeat (STR) markers...
October 10, 2017: Zhonghua Yi Xue Yi Chuan Xue za Zhi, Zhonghua Yixue Yichuanxue Zazhi, Chinese Journal of Medical Genetics
https://www.readbyqxmd.com/read/28978246/prevention-and-treatment-of-fetal-cytomegalovirus-infection-with-cytomegalovirus-hyperimmune-globulin-a-multicenter-study-in-madrid
#13
Daniel Blázquez-Gamero, A Galindo Izquierdo, T Del Rosal, F Baquero-Artigao, N Izquierdo Méndez, M Soriano-Ramos, P Rojo Conejo, M I González-Tomé, A García-Burguillo, N Pérez Pérez, V Sánchez, J T Ramos-Amador, M De la Calle
INTRODUCTION: Cytomegalovirus (CMV) is the leading cause of congenital infection worldwide. Data about the management of CMV infection in pregnant women are scarce, and treatment options are very limited. The aim of the study is to investigate the effectiveness of cytomegalovirus hyperimmune globulin (CMV-HIG) for the prevention and treatment of congenital CMV (cCMV) infection. MATERIALS AND METHODS: A retrospective observational study was conducted in three tertiary hospitals in Madrid...
October 4, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28973897/mapping-allele-with-resolved-carrier-status-of-robertsonian-and-reciprocal-translocation-in-human-preimplantation-embryos
#14
Jiawei Xu, Zhen Zhang, Wenbin Niu, Qingling Yang, Guidong Yao, Senlin Shi, Haixia Jin, Wenyan Song, Lei Chen, Xiangyang Zhang, Yihong Guo, Yingchun Su, Linli Hu, Jun Zhai, Yile Zhang, Fangli Dong, Yumei Gao, Wenhui Li, Shiping Bo, Mintao Hu, Jun Ren, Lei Huang, Sijia Lu, X Sunney Xie, Yingpu Sun
Reciprocal translocations (RecT) and Robertsonian translocations (RobT) are among the most common chromosomal abnormalities that cause infertility and birth defects. Preimplantation genetic testing for aneuploidy using comprehensive chromosome screening for in vitro fertilization enables embryo selection with balanced chromosomal ploidy; however, it is normally unable to determine whether an embryo is a translocation carrier. Here we report a method named "Mapping Allele with Resolved Carrier Status" (MaReCs), which enables chromosomal ploidy screening and resolution of the translocation carrier status of the same embryo...
September 27, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28971718/evaluation-of-the-relation-between-placental-weight-and-placental-weight-to-foetal-weight-ratio-and-the-causes-of-stillbirth-a-retrospective-comparative-study
#15
Norbert Pásztor, János Sikovanyecz, Attila Keresztúri, Zoltan Kozinszky, Gábor Németh
The aim of the present study was to evaluate the clinical importance of placental weight (PW) and placental weight to foetal weight (PW/FW) ratio according to maternal characteristics, pathological conditions in obstetrics and the causes of foetal death by category in stillbirths. The results of autopsies and placental histopathological examinations for 145 singleton stillbirths were reviewed retrospectively. Pathological features of the placenta were significantly associated with lower PW compared to the group with no pathological placental parameters (230 grams versus 295 grams, p = ...
October 3, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28968427/evolution-in-fecal-bacterial-viral-composition-in-infants-of-two-central-african-countries-gabon-and-republic-of-the-congo-during-their-first-month-of-life
#16
Lionel Brazier, Eric Elguero, Claudine Kombila Koumavor, Nicolas Renaud, Franck Prugnolle, Frédéric Thomas, Simon Ategbo, Moyen Engoba, Obengui, Eric M Leroy, Patrick Durand, François Renaud, Pierre Becquart
Few studies have analyzed the gut microbiota of child in unindustrialized countries, but none during the first month of life. Stool samples were collected from healthy newborns in hospitals of Gabon (n = 6) and Republic of the Congo (n = 9) at different time points during the first month of life: meconium, day 2 (D02), day 7 (D07) and day 28 (D28). In addition, one fecal sample was collected from each mother after delivery. Metagenomic sequencing was performed to determine the bacterial communities, and multiplex real-time PCR was used to detect the presence of seven enteric viruses (rotavirus a, adenovirus, norovirus I and II, sapovirus, astrovirus, enterovirus) in these samples...
2017: PloS One
https://www.readbyqxmd.com/read/28965779/pregnancy-exposure-to-quetiapine-therapeutic-drug-monitoring-in-maternal-blood-amniotic-fluid-and-cord-blood-and-obstetrical-outcomes
#17
Michael Paulzen, Tamme W Goecke, Maxim Kuzin, Marc Augustin, Gerhard Gründer, Georgios Schoretsanitis
RATIONALE: This prospective study is the first to measure and correlate quetiapine concentrations in maternal blood, amniotic fluid and umbilical cord blood to account for the distribution of quetiapine. METHODS: Concentrations of quetiapine are quantified in seven mother infant pairs at the time of delivery. Data are provided as median values, first (Q1) and third (Q3) quartiles and ranges. To account for the penetration ratio, the concentration of quetiapine in amniotic fluid and cord blood was divided by maternal concentrations...
September 28, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28965437/midtrimester-isolated-oligohydramnios-in-monochorionic-diamniotic-multiple-gestations
#18
Andrew H Chon, Lisa M Korst, Ryan D Assaf, Arlyn Llanes, Joseph G Ouzounian, Ramen H Chmait
OBJECTIVE: To describe the natural history and perinatal outcomes of monochorionic diamniotic twins with midtrimester isolated oligohydramnios (iOligo). MATERIALS AND METHODS: We performed a retrospective study of iOligo patients who were initially referred for the management of evolving twin-twin transfusion syndrome (TTTS) or selective intrauterine growth restriction (sIUGR). iOligo was defined as a maximum vertical pocket of amniotic fluid of ≤ 2 cm in the iOligo twin's sac and normal fluid level (> 2 and < 8 cm) in the co-twin's sac...
October 1, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28964823/are-amniotic-fluid-neutrophils-in-women-with-intraamniotic-infection-and-or-inflammation-of-fetal-or-maternal-origin
#19
Nardhy Gomez-Lopez, Roberto Romero, Yi Xu, Yaozhu Leng, Valeria Garcia-Flores, Derek Miller, Suzanne M Jacques, Sonia S Hassan, Jonathan Faro, Adham Alsamsam, Ali Alhousseini, Hunter Gomez-Roberts, Bogdan Panaitescu, Lami Yeo, Eli Maymon
BACKGROUND: Neutrophils are the most abundant white blood cells found in the amniotic cavity of women with intraamniotic infection and/or inflammation. The current belief is that these neutrophils are of fetal origin. However, abundant neutrophils have been found in the amniotic fluid of women with a severe acute maternal inflammatory response but without a fetal inflammatory response in the placenta, suggesting that these innate immune cells can also be of maternal origin or a mixture of both fetal and maternal neutrophils...
September 28, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28961562/maternal-death-due-to-amniotic-fluid-embolism-a-national-study-in-france
#20
Marie-Pierre Bonnet, Diane Zlotnik, Monica Saucedo, Dominique Chassard, Marie-Hélène Bouvier-Colle, Catherine Deneux-Tharaux
BACKGROUND: A structured definition of amniotic fluid embolism (AFE) based on 4 criteria was recently proposed for use in research by the Society for Maternal-Fetal Medicine (SMFM) and the Amniotic Fluid Embolism Foundation. The main objective of this study was to review all AFE-related maternal deaths in France during 2007-2011 according to the presence or not of all these 4 diagnostic criteria. METHODS: Maternal deaths due to AFE were identified by the national experts committee of the French Confidential Enquiry into Maternal Deaths during 2007-2011 (n = 39)...
September 28, 2017: Anesthesia and Analgesia
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