keyword
https://read.qxmd.com/read/38633762/the-epidemiology-of-cryptorchidism-and-potential-risk-factors-including-endocrine-disrupting-chemicals
#1
REVIEW
Stine A Holmboe, Astrid L Beck, Anna-Maria Andersson, Katharina M Main, Niels Jørgensen, Niels E Skakkebæk, Lærke Priskorn
Congenital cryptorchidism, also known as undescended testis, is the condition where one or both testes are not in place in the scrotum at birth and is one of the most common birth defects in boys. Temporal trends and geographic variation in the prevalence of cryptorchidism from 1% to 9% have been reported in prospective cohort studies. The testes develop in the abdominal cavity and descend to the scrotum in two phases, which should be completed by gestational week 35. Thus, the risk of cryptorchidism is higher in preterm boys...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38626639/encysted-spermatic-cord-hydrocele-a-case-series
#2
JOURNAL ARTICLE
Shankar Adhikari, Om Prakash Bhatta, Prashant Bhetwal, Sachin Awasthi
INTRODUCTION AND IMPORTANCE: Encysted spermatic cord hydrocele is a rare anomaly characterized by obstruction of processus vaginalis closure. Clinically, it presents as a swelling in the inguinal region extending to the upper scrotum and does not communicate with the peritoneal cavity. It is often mistaken for indirect inguinal hernias, inguinal lymphadenopathy, undescended testis, and primary tumors of the cord in infants and children, making the diagnosis challenging. CASE PRESENTATION: We report the cases of five male patients aged nine months to 12 years who presented with painless swelling on the right side of the scrotal region...
April 6, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38532895/cryptorchidism-and-puberty
#3
REVIEW
Wiwat Rodprasert, Helena E Virtanen, Jorma Toppari
Cryptorchidism is the condition in which one or both testes have not descended adequately into the scrotum. The congenital form of cryptorchidism is one of the most prevalent urogenital anomalies in male newborns. In the acquired form of cryptorchidism, the testis that was previously descended normally is no longer located in the scrotum. Cryptorchidism is associated with an increased risk of infertility and testicular germ cell tumors. However, data on pubertal progression are less well-established because of the limited number of studies...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38532380/does-the-contralateral-testicular-volume-decide-the-need-for-diagnostic-laparoscopy-in-cases-of-unilateral-impalpable-undescended-testis
#4
JOURNAL ARTICLE
Ahmed Elrouby, Mahmoud Ghalab, Mostafa Kotb
BACKGROUND: This study aimed the evaluation of the value of the calculated volume of a normal testis to predict the status of its contralateral impalpable side and hence decide the importance of laparoscopic exploration. METHODS: Patients with unilateral impalpable undescended testis - as confirmed by clinical and sonographic examination- were enrolled in our prospective interventional study between November 2018 and August 2022 at Elshatby University Hospital, Faculty of Medicine, Alexandria University...
March 26, 2024: BMC Urology
https://read.qxmd.com/read/38451346/comparison-of-scrotal-and-inguinal-orchiopexy-for-palpable-undescended-testis-a-meta-analysis-of-randomized-controlled-trials
#5
REVIEW
Irfan Wahyudi, Putu Angga Risky Raharja, Gerhard Reinaldi Situmorang, Arry Rodjani
INTRODUCTION: Scrotal and inguinal orchiopexy are two commonly used surgical approaches for palpable undescended testis (UDT), each with distinct advantages. However, the optimal approach remains a matter of debate, warranting a comprehensive meta-analysis of randomized controlled trials (RCTs) to guide clinical decision-making. MATERIALS AND METHODS: A comprehensive literature search was conducted, adhering to PRISMA guidelines, to select RCTs comparing scrotal and inguinal orchiopexy for palpable UDT...
March 7, 2024: Pediatric Surgery International
https://read.qxmd.com/read/38436980/mini-puberty-physiological-and-disordered-consequences-and-potential-for-therapeutic-replacement
#6
JOURNAL ARTICLE
Julia Rohayem, Emma C Alexander, Sabine Heger, Anna Nordenström, Sasha R Howard
There are 3 physiological waves of central hypothalamic-pituitary-gonadal (HPG) axis activity over the lifetime. The first occurs during fetal life, the second-termed "mini-puberty"-in the first months after birth, and the third at puberty. After adolescence, the axis remains active all through adulthood. Congenital hypogonadotropic hypogonadism (CHH) is a rare genetic disorder characterized by a deficiency in hypothalamic gonadotropin-releasing hormone (GnRH) secretion or action. In cases of severe CHH, all 3 waves of GnRH pulsatility are absent...
March 4, 2024: Endocrine Reviews
https://read.qxmd.com/read/38415237/techniques-of-staged-laparoscopic-orchidopexy-for-high-intra-abdominal-testes-in-children-a-systematic-review-and-meta-analysis
#7
JOURNAL ARTICLE
Nitinkumar Bhajandas Borkar, Charu Tiwari, Debajyoti Mohanty, Deepti Vepakomma, Nilesh Nagdeve
BACKGROUND: Laparoscopic exploration is currently considered the gold standard for managing nonpalpable intraabdominal testes. The problem of short vascular pedicle is addressed in Fowler-Stephen (FS) technique by the division of testicular vessels and in Shehata technique (ST) by traction on testicular vessels. There is a lack of the consensus among pediatric surgeons on the choice of one technique over other. This analysis compares the reported outcomes of staged laparoscopic orchidopexy by ST with the time tested FS technique in managing high intraabdominal undescended testis...
2024: Urology Annals
https://read.qxmd.com/read/38410527/an-adult-right-inguinal-hernia-and-cryptorchidism-treated-simultaneously-with-laparoscopic-transabdominal-preperitoneal-repair-and-laparoscopic-orchiectomy-a-case-report
#8
Dai Kimura, Yusuke Miyagawa, Masafumi Miyao, Hideyasu Matumura, Shoichiro Koike
Pediatric health checkups have been mandatory for all citizens since 1966 based on the Maternal and Child Health Law in Japan, and cryptorchidism or undescended testis in adult males are rare. We report a case of an adult right inguinal hernia and cryptorchidism treated simultaneously with laparoscopic transabdominal preperitoneal repair and laparoscopic orchiectomy. A 35-year-old man came to our department with a chief complaint of bulging in the right inguinal region for several months. He was diagnosed with a right inguinal hernia and was scheduled for transabdominal preperitoneal repair...
February 2024: Journal of Surgical Case Reports
https://read.qxmd.com/read/38405236/long-term-outcome-of-laparoscopic-surgery-for-nonpalpable-undescended-testis
#9
JOURNAL ARTICLE
Nachiket Milind Joshi, Rasik Shamji Shah
AIMS AND OBJECTIVES: The aim of this study was to objectively assess the long-term results of laparoscopic orchidopexy in patients who were diagnosed clinically to have nonpalpable undescended testis (UDT). MATERIALS AND METHODS: All operated cases of nonpalpable UDT from January, 2000, to January, 2014, were reviewed. After informed consent, all patients were subjected to a color Doppler ultrasound examination to assess the location of the testis, its size, blood supply, and consistency...
2024: Journal of Indian Association of Pediatric Surgeons
https://read.qxmd.com/read/38391373/angiolipoma-of-testis-in-a-case-of-undescended-testis-a-rare-occurrence
#10
JOURNAL ARTICLE
Sudha Sharma, Puneet Jain
No abstract text is available yet for this article.
July 26, 2023: Indian Journal of Pathology & Microbiology
https://read.qxmd.com/read/38373213/anogenital-distance-in-a-cohort-of-169-infant-boys-with-uni-or-bilateral-cryptorchidism-including-18-boys-with-vanishing-testes
#11
JOURNAL ARTICLE
Dina Cortes, Margit Bistrup Fischer, Andrea E Hildorf, Erik Clasen-Linde, Simone Hildorf, Anders Juul, Katharina M Main, Jorgen Thorup
STUDY QUESTION: Do different boys with different types of cryptorchidism exhibit different anogenital distances (AGDs)? SUMMARY ANSWER: Length of AGD seemed to differ in different groups of patients with cryptorchidism. WHAT IS KNOWN ALREADY: AGD, which is used as an indicator of prenatal androgen action, tends to be shorter in boys with cryptorchidism compared to unaffected boys. Shorter AGDs have also been reported in boys with hypospadias, in men with poor semen quality, and in men with testicular cancer...
February 19, 2024: Human Reproduction
https://read.qxmd.com/read/38349599/risk-for-testicular-germ-cell-tumors-and-spermatogenesis-failure-in-post-pubertal-undescended-testes
#12
JOURNAL ARTICLE
Rifat Burak Ergül, Zeynep Bayramoğlu, Avni Merter Keçeli, M İrfan Dönmez
PURPOSE: Cryptorchidism is a well-defined risk factor for testicular germ cell tumors, whereas the underlying mechanisms have not been fully elucidated. Surgical procedures to reposition undescended testicles into the scrotum (orchidopexy) in early childhood are recommended both to increase fertility potential and to reduce the risk of developing testicular tumors. However, treatment in the post-pubertal period is controversial. The aim of this study is to review the histopathology of orchiectomy specimens and determination of spermatogenesis in post-pubertal patients with non-treated cryptorchidism...
February 13, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38346721/evaluation-of-testicular-stiffness-in-boys-with-unilateral-cryptorchidism-after-orchiopexy-by-ultrasound-strain-elastography
#13
JOURNAL ARTICLE
Yuichi Sato, Yusuke Kirihana, Satoru Meguro, Ryo Tanji, Akifumi Onagi, Ruriko Honda-Takinami, Kanako Matsuoka, Seiji Hoshi, Junya Hata, Hidenori Akaihata, Soichiro Ogawa, Motohide Uemura, Yoshiyuki Kojima
PURPOSE: We assessed the stiffness of unilateral undescended testes after orchiopexy, examining its value in tracking histopathological changes and fertility potential during postoperative follow-up. Additionally, we explored the optimal timing for surgery based on testicular stiffness. PATIENTS AND METHODS: Thirty-six boys who had been diagnosed with unilateral undescended testis and treated with orchiopexy were included in the study. Testicular stiffness was evaluated several times over respective follow-up periods by ultrasound strain elastography after orchiopexy...
February 9, 2024: Fukushima Journal of Medical Science
https://read.qxmd.com/read/38321746/-a-case-of-testicular-torsion-of-retractile-testis-requiring-orchidectomy
#14
JOURNAL ARTICLE
Yasuhiro Numata, Hiroki Ito, Mitsuteru Matsuoka, Taku Sasaki, Yutaro Hayashi, Takahiko Watanabe, Masahiro Inoue, Daiki Ueno, Kazuki Kobayashi
We report a case of testicular torsion in an 8-year-old who was referred to our hospital for right groin pain. He was diagnosed with right retractile testis during a 12-month check-up. However, instead of performing orchiopexy, he was placed under observation until the age of 5, after which he did not seek medical attention. Physical examination revealed swelling and tenderness in the right inguinal region and no palpable testis in the right scrotum. Ultrasound and computed tomography revealed right testicular torsion, and emergency surgery was performed...
January 2024: Hinyokika Kiyo. Acta Urologica Japonica
https://read.qxmd.com/read/38313930/testicular-torsion-in-the-undescended-testis-of-a-four-year-old-a-delayed-diagnosis
#15
Leena K Alshaibani, Sara K Alshaibani
In this report, we discuss the case of a four-year-old boy known to have global developmental delay (GDD) and infantile spasm. The child was brought to the emergency department (ER) with a tender inguinal swelling and fever. Notably, there was no previous indication of an undescended testicle (UDT), and the scrotum was not examined in the ER initially. The abdominal radiograph was unremarkable, and an ultrasound of the groin was requested to investigate the nature of the swelling. The ultrasound yielded a differential diagnosis of direct or indirect inguinal hernia containing intestinal loops or a necrotic lymph node...
January 2024: Curēus
https://read.qxmd.com/read/38281149/-current-management-of-undescended-testes-in-hungary-where-are-we-now
#16
JOURNAL ARTICLE
Alexandra Varga, Réka Tardi, Tamás Kovács
No abstract text is available yet for this article.
January 28, 2024: Orvosi Hetilap
https://read.qxmd.com/read/38273375/a-renal-aplasia-case-mimicking-radiologically-as-unilateral-renal-agenesis-in-a-child-with-spina-bifida-atresia-ani-and-unilateral-undescended-testis-a%C3%A2-case-report
#17
JOURNAL ARTICLE
Prahara Yuri, Muhammad Anwar Irzan, Tanaya Ghinorawa, Muchamad Ridotu Solichin, Ery Kus Dwianingsih
BACKGROUND: As a result of the failure of embryogenic kidney formation, a condition can occur where not a single kidney appears and this phenomenon is known as unilateral renal agenesis (URA). Both aplastic and dysplastic kidney are different from renal agenesis, atrophy and renal hypoplasia. However, from this case report it can be seen that there are similarities, both radiologically and macroscopically, between cases of unilateral renal aplasia and renal agenesis. CASE PRESENTATION: A 2 year old Javanese boy came to the health facility with complaints of recurrent fever and urinary tract symptoms such as dysuria and straining...
January 26, 2024: Journal of Medical Case Reports
https://read.qxmd.com/read/38270180/the-hidden-burden-of-pediatric-urology-in-sub-saharan-africa-an-analysis-of-hospital-admission-data-from-three-east-african-health-centres
#18
JOURNAL ARTICLE
Alessandro Calisti, Diaaeldinn Yaseen Salman, Kibreab Belay, Andrea Mombo, Boniphace Tresphory, Giovanni Giuliani, Martina Sertori, Gian Battista Parigi
Specialist facilities for children are still unavailable in some Sub-Saharan African contexts. It is the case of pediatric urology, whose recent advances are still largely unshared. Prenatal diagnosis of urinary abnormalities (CAKUT) is largely unknown. Early recognition and referral of Undescended testis (UDT), Hypospadia, bladder exstrophy epispadias complex, ambiguous genitalia, stone disease, and tumours are uncommon in rural areas. Missed diagnosis is not uncommon and delayed management is associated with poor outcomes...
January 23, 2024: La Pediatria Medica e Chirurgica: Medical and Surgical Pediatrics
https://read.qxmd.com/read/38270075/obliteration-of-the-processus-vaginalis-after-testicular-descent
#19
JOURNAL ARTICLE
Feridun Cahit Tanyel
The testis develops in the abdominal cavity and descends into the scrotum. Although numerous theories have been proposed, the mechanism of descent and the reason for its inhibition remain unknown. Furthermore, none of the explanations account for the other occurrences related to the descent, such as failed obliteration of the processus vaginalis, or the reasons for the decrease in fertility and increase in the risk of malignancy associated with an undescended testis. The gubernaculum is a primitive mesenchymal tissue that was first described in 1786...
January 25, 2024: Balkan Medical Journal
https://read.qxmd.com/read/38265486/wt1-exon-10-missense-variant-in-a-pediatric-patient-with-focal-segmental-glomerulosclerosis-with-embryonal-hyperplasia
#20
JOURNAL ARTICLE
Mari Kurokawa, Manao Nishimura, Kei Nishiyama, Kentaro Matsuoka, China Nagano, Yoshitsugu Kaku
A 6-year-old boy was diagnosed with chromosomal abnormalities (48,XYY, + 21[11]/46,XY[19]) at 4 months of age after a physical examination revealed an undescended testis and a dwarf penis. He also had mild renal dysfunction and severe proteinuria, and kidney biopsy at 2 years of age revealed focal segmental glomerulosclerosis. Genetic analysis to investigate suspected WT1 gene abnormalities revealed a novel variant in NM_024426.6:exon10:c.1506 T > A (p.(Asp502Glu))...
January 24, 2024: Pediatric Nephrology
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