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https://www.readbyqxmd.com/read/28538287/cost-utility-analysis-of-reconstruction-compared-with-primary-amputation-for-patients-with-severe-lower-limb-trauma-in-colombia
#1
Mateo Ceballos, Carlos Oliver Valderrama, Luis Esteban Orozco, Laura Sánchez, Juan Pablo Valderrama, Luz Helena Lugo
BACKGROUND: To establish, from the health system perspective, the cost-utility relationship of limb reconstruction compared with primary amputation for patients over 32 years with grade IIIB and IIIC severe lower limb trauma in Colombia, S.A. METHODS: A Markov model was built including different short-term and long-term states that represent the main events that a patient could experience after a lower limb amputation or a reconstruction. A 42-year time horizon was considered for the base case...
May 17, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28535105/the-importance-of-economic-perspective-and-quantitative-approaches-in-oncology-value-frameworks-of-drug-selection-and-shared-decision-making
#2
A Reginald Waldeck, Marc F Botteman, Richard E White, Ben A van Hout
The debate around value in oncology drug selection has been prominent in recent years, and several professional bodies have furthered this debate by advocating for so-called value frameworks. Herein, we provide a viewpoint on these value frameworks, emphasizing the need to consider 4 key aspects: (1) the economic underpinnings of value; (2) the importance of the perspective adopted in the valuation; (3) the importance of the difference between absolute and relative measures of risk and measuring patient preferences; and (4) the recognition of multiple quality-of-life (QoL) domains, and the aggregation and valuation of those domains, through utilities within a multicriteria decision analysis, may allow prioritization of QoL above the tallying of safety events, particularly in a value framework focusing on the individual patient...
June 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28529098/differences-in-the-economic-valuation-and-determining-factors-of-informal-care-over-time-the-case-of-blood-cancer
#3
Marta Ortega-Ortega, Roberto Montero-Granados, Juan de Dios Jiménez-Aguilera
OBJECTIVE: To estimate differences in the economic valuation and sociodemographic and clinical factors associated with informal care between phases of the treatment in the case of blood cancer patients. METHODS: 139 haematological cancer patients who underwent a stem cell transplantation completed a longitudinal questionnaire according to 3 phases of the treatment: short-term (pre-transplant), medium-term (1st year post-transplant) and long-term (2nd-6th year post-transplant)...
May 19, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28528557/-naming-and-framing-the-impact-of-labeling-on-health-state-values-for-multiple-sclerosis
#4
Colin Green, Elizabeth Goodwin, Annie Hawton
INTRODUCTION: Health state valuation is a key input in many economic evaluations that inform resource allocation across competing healthcare interventions. Empirical evidence has shown that, in preference elicitation surveys, respondents may value a health state differently if they are aware of the condition causing it ('labeling effects'). This study investigates the impact of including a multiple sclerosis (MS) label for valuation of MS health states. METHODS: Health state values for MS were elicited using two internet-based surveys in representative samples of the UK population ( n = 1702; n = 1788)...
May 1, 2017: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/28521377/-checklist-for-the-development-and-assessment-of-cost-of-illness-studies
#5
Dirk Müller, Stephanie Stock, Charalabos-Markos Dintsios, Nadja Chernyak, Andreas Gerber-Grote, Tristan Daniel Gloede, Benita Hermann, Eduard Huppertz, Fabian Jülich, Sarah Mostardt, Juliane Köberlein-Neu, Anne Prenzler, Hans-Joachim Salize, Sara Santos, Benjamin Scheckel, Astrid Seidl, Katharina Wahlers, Andrea Icks
Background Cost-of-illness (CoI) studies are important instruments for estimating the socioeconomic burden of specified diseases. CoI studies provide important information about the cost structure of a disease, the resulting research need, approaches to improve aspects of care and, monetary consequences from different perspectives. This information can be useful for healthcare research and health policy. Due to heterogeneity of available Cost-of-Illness studies, the working group 'Health Economics' of the German Network for Healthcare Research (DNVF) in accordance with the German Society for Health Economics (DGGÖ) developed an instrument for the planning, conduct and assessment of CoI studies...
May 18, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/28487850/willingness-to-pay-for-social-health-insurance-in-central-vietnam
#6
Lan Hoang Nguyen, Anh Thuan Duc Hoang
BACKGROUND: A social health insurance (SHI) program was implemented in Vietnam in 1992. Participation is compulsory for some groups, such as formal-sector workers and voluntary for other groups. In 2013, 68% of the total population was covered by SHI, with most enrollees from compulsory groups. Enrollment has remained low among persons whose enrollment is voluntary. As a result, households face financial risk due to high out-of-pocket payments for health care. The goal of this study is to identify willingness to pay (WTP) for the SHI scheme among persons whose enrollment is voluntary and to examine factors that influence their choice...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28486711/momentary-associations-between-reported-craving-and-valuing-health-in-daily-smokers
#7
Robert Ross MacLean, Steve Martino, Kathleen M Carroll, Joshua M Smyth, Aaron L Pincus, Stephen J Wilson
Introduction: Research suggests that a blunted response to nondrug rewards, especially under conditions associated with strong cigarette cravings, is associated with reduced abstinence motivation in daily smokers. One limitation of previous studies is that they have largely focused on monetary rewards as broad representative of nondrug rewards. It remains unclear whether craving dampens responses to more abstract nondrug rewards, such as personal values. Personal values often have a positive valence and are frequently assumed to remain stable across time and situations...
June 1, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28471985/the-clinical-significance-of-scd14-st-for-blood-biomarker-in-neonatal-hematosepsis-a-diagnostic-accuracy-study
#8
Ting Xiao, Li-Ping Chen, Li-Hua Zhang, Fu-Huang Lai, Li Zhang, Qun-Feng Qiu, Rong-Liang Que, SiSi Xie, Ding-Chang Wu
Hematosepsis is a systemic inflammatory response syndrome (SIRS) with suspected or confirmed infection, which is the most common infectious disease in clinical neonatal intensive care unit. As the rapid development of neonatal hematosepsis caused by various basic diseases, the mortality rate is high, and there are some sequelae.We report the lasted study to date with 96 cases from Fujian Longyan First Hospital between 2013 and 2015. The aim of our study is to explore the value of soluble cluster of differentiation 14 subtype (sCD14-ST) in whole blood for differential diagnosis of neonatal hematosepsis at an early stage, and used in evaluation of the severity about sepsis combined with acute physiology and chronic health evaluation II (APACHE-II) score, procalcitonin (PCT), C reactive protein (CRP), and leukocyte (WBC)...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28453945/an-approach-to-reconciling-competing-ethical-principles-in-aggregating-heterogeneous-health-preferences
#9
Barry Dewitt, Alexander Davis, Baruch Fischhoff, Janel Hanmer
BACKGROUND: Health-related quality of life (HRQL) scores are used extensively to quantify the effectiveness of medical interventions. Societal preference-based HRQL scores aim to produce societal valuations of health by aggregating valuations from individuals in the general population, where each aggregation procedure embodies different ethical principles, as explained in social choice theory. METHODS: Using the Health Utilities Index as an exemplar, we evaluate societal preference-based HRQL measures in the social choice theory framework...
April 1, 2017: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/28453065/-identification-of-capacities-in-environmental-health-from-environmental-authorities-in-colombia
#10
Carlos A Agudelo-Calderón, Juan C García-Ubaque, Rocío Robledo-Martínez, Cesar A García-Ubaque, Martha L Vaca-Bohórquez
Objectives To diagnose the capabilities that environmental authorities and the Ministry of Environment and Sustainable Development have to assume their role in environmental health, based on the capacity model of the United Nations Program for Development UNDP. Method Document review, interviews on key issues and a commented survey were conducted. 84 entities were selected for a tailored survey; complete information was obtained from 76 institutions. Results The valuation of environment favorability was within the acceptable and unfavorable categories; knowledge management capabilities were found to be precarious and assessment of functional capabilities ranged between appropriate and acceptable...
August 2016: Revista de Salud Pública
https://www.readbyqxmd.com/read/28438919/ecosystem-change-and-human-health-implementation-economics-and-policy
#11
REVIEW
S K Pattanayak, R A Kramer, J R Vincent
Several recent initiatives such as Planetary Health, EcoHealth and One Health claim that human health depends on flourishing natural ecosystems. However, little has been said about the operational and implementation challenges of health-oriented conservation actions on the ground. We contend that ecological-epidemiological research must be complemented by a form of implementation science that examines: (i) the links between specific conservation actions and the resulting ecological changes, and (ii) how this ecological change impacts human health and well-being, when human behaviours are considered...
June 5, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28436139/improving-scope-sensitivity-in-contingent-valuation-joint-and-separate-evaluation-of-health-states
#12
José Luis Pinto-Prades, José Antonio Robles-Zurita, Fernando-Ignacio Sánchez-Martínez, José María Abellán-Perpiñán, Jorge Martínez-Pérez
We present data of a contingent valuation survey, testing the effect of evaluation mode on the monetary valuation of preventing road accidents. Half of the interviewees was asked to state their willingness to pay (WTP) to reduce the risk of having only 1 type of injury (separate evaluation, SE), and the other half of the sample was asked to state their WTP for 4 types of injuries evaluated simultaneously (joint evaluation, JE). In the SE group, we observed lack of sensitivity to scope while in the JE group WTP increased with the severity of the injury prevented...
April 24, 2017: Health Economics
https://www.readbyqxmd.com/read/28425680/adaptation-to-health-states-sick-yet-better-off
#13
Patricia Cubí-Mollá, Mireia Jofre-Bonet, Victoria Serra-Sastre
Healthcare funding decisions in the UK rely on health state valuations of the general public. However, it has been shown that there is disparity between the valuation of the impact of hypothetical conditions on health and the reported health by those experiencing them. Patients' adaptation to health states is among the most common explanations for this discrepancy. Being diagnosed with a disease appears to affect individual perception of health over time so that better subjective health may be reported over a disease trajectory...
April 20, 2017: Health Economics
https://www.readbyqxmd.com/read/28420153/health-related-quality-of-life-of-the-general-german-population-in-2015-results-from-the-eq-5d-5l
#14
Manuel B Huber, Julia Felix, Martin Vogelmann, Reiner Leidl
The EQ-5D-5L is a widely used generic instrument to measure health-related quality of life. This study evaluates health perception in a representative sample of the general German population from 2015. To compare results over time, a component analysis technique was used that separates changes in the description and valuation of health states. The whole sample and also subgroups, stratified by sociodemographic parameters as well as disease affliction, were analyzed. In total, 2040 questionnaires (48.4% male, mean age 47...
April 16, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28418833/willingness-to-pay-in-caregivers-of-patients-affected-by-schizophrenia
#15
Claudiane Salles Daltio, Cecilia Attux, Marcos Bosi Ferraz
BACKGROUND: Schizophrenia is a debilitating disorder that often requires the affected individual to receive care from a caregiver. Willingness to Pay (WTP) technique allows a valuation of the health state preferences by assessing the impact of the disease and translating it into monetary terms. AIMS OF THE STUDY: The objective was to determine the WTP of schizophrenic patients' caregivers on a hypothetical recovery scenario and correlate it to socio-demographic and clinical characteristics, Knowledge of Disease, Quality of life and Burden of Disease...
March 1, 2017: Journal of Mental Health Policy and Economics
https://www.readbyqxmd.com/read/28411064/health-benefits-of-a-reduction-of-pm10-and-no2-exposure-after-implementing-a-clean-air-plan-in-the-agglomeration-lausanne-morges
#16
Alberto Castro, Nino Künzli, Thomas Götschi
Exposure to urban air pollution has been associated with adverse effects on cardio-vascular and respiratory health, both short and long term. Consequently, governments have applied policies to reduce air pollution. Quantitative health impact assessments of hypothetic changes in air pollution have been conducted at national and global level, but assessments of observed air pollution changes associated with specific clean air policies at a local or regional scale remain scarce. This study estimates health impacts attributable to a decrease in PM10 and NO2 exposure in the Agglomeration of Lausanne-Morges (ALM), Switzerland, between 2005 and 2015, corresponding to the implementation period of a supra-municipal plan of measures to reduce air pollution in different sectors such as transport, energy, and industry (called Plan OPair 05)...
April 5, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28410806/external-costs-of-pm2-5-pollution-in-beijing-china-uncertainty-analysis-of-multiple-health-impacts-and-costs
#17
Hao Yin, Massimo Pizzol, Linyu Xu
Some cities in China are facing serious air pollution problems including high concentrations of particles, SO2 and NOx. Exposure to PM2.5, one of the primary air pollutants in many cities in China, is highly correlated with various adverse health impacts and ultimately represents a cost for society. The aim of this study is to assess health impacts and external costs related to PM2.5 pollution in Beijing, China with different baseline concentrations and valuation methods. The idea is to provide a reasonable estimate of the total health impacts and external cost due to PM2...
April 11, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28408007/instrument-defined-estimates-of-the-minimally-important-difference-for-eq-5d-5l-index-scores
#18
COMPARATIVE STUDY
Nathan S McClure, Fatima Al Sayah, Feng Xie, Nan Luo, Jeffrey A Johnson
BACKGROUND: The five-level EuroQol five-dimensional questionnaire (EQ-5D-5L) is a preference-based measure of health-related quality of life (HRQOL), which yields an index score anchored at 0 (dead) and 1 (full health). We lack evidence on estimates for the minimally important difference (MID) of the EQ-5D-5L that will help in interpreting differences or changes in HRQOL measured by this scale score. OBJECTIVES: To estimate the MID of the EQ-5D-5L index score for available scoring algorithms including algorithms from Canada, China, Spain, Japan, England, and Uruguay...
April 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/28401587/valuation-of-life-as-outcome-and-mediator-of-a-depression-intervention-for-older-african-americans-the-get-busy-get-better-trial
#19
Laura N Gitlin, Jeanine M Parisi, Jin Huang, Laraine Winter, David L Roth
OBJECTIVE: Previously, we showed that Get Busy Get Better (GBGB), a 10-session multicomponent home-based, behavioral intervention, reduced depressive symptom severity in older African Americans. As appraising the value of life is associated with depressive symptoms, this study examined whether GBGB enhanced positive appraisals of life and if, in turn, this mediated treatment effects on depressive symptoms. METHODS: Data were from a single-blind parallel randomized trial involving 208 African Americans (≥55 years old) with depressive symptoms (Patient Health Questionnaire, PHQ-9 ≥5)...
April 12, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28395860/application-of-natural-resource-valuation-concepts-for-development-of-sustainable-remediation-plans-for-groundwater
#20
John A Connor, Shawn Paquette, Thomas McHugh, Elaine Gie, Mark Hemingway, Gino Bianchi
This paper explores the application of natural resource assessment and valuation procedures as a tool for developing groundwater remediation strategies that achieve the objectives for health and environmental protection, in balance with considerations of economic viability and conservation of natural resources. The natural resource assessment process, as applied under U.S. and international guidelines, entails characterization of groundwater contamination in terms of the pre-existing beneficial services of the impacted resource, the loss of these services caused by the contamination, and the measures and associated costs necessary to restore or replace the lost services...
April 7, 2017: Journal of Environmental Management
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