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https://www.readbyqxmd.com/read/28219389/valuation-of-the-eq-5d-5l-with-composite-time-trade-off-for-the-german-population-an-exploratory-study
#1
Kristina Ludwig, J-Matthias Graf von der Schulenburg, Wolfgang Greiner
BACKGROUND: The EuroQol Group has extended the severity levels of the EQ-5D from three to five (EQ-5D-5L). There are valuation studies worldwide planned in order to convert the EQ-5D-5L health states into a single preference-based summary score based on country-specific value sets of social health status preference valuations. The EuroQol Group developed an internationally standardised EQ-5D-5L valuation protocol. Based on the experiences of the first wave of valuation studies applying the protocol, a number of modifications to the implementation of composite time trade-off (cTTO) were proposed and tested in an exploratory study in Germany...
February 20, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28214449/-they-treated-me-like-crap-and-i-know-it-was-because-i-was-native-the-healthcare-experiences-of-aboriginal-peoples-living-in-vancouver-s-inner-city
#2
Ashley Goodman, Kim Fleming, Nicole Markwick, Tracey Morrison, Louise Lagimodiere, Thomas Kerr
There is growing evidence that Aboriginal peoples often experience healthcare inequalities due to racism. However, research exploring the healthcare experiences of Aboriginal peoples who use illicit substances is limited, and research rarely accounts for how multiple accounts of stigma intersect and contribute to the experiences of marginalized populations. Our research aimed to explore the healthcare experiences of Aboriginal peoples who use illicit drugs and or illicit alcohol (APWUID/A) living in Vancouver's inner city...
January 26, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28212966/estimating-preferences-for-complex-health-technologies-lessons-learned-and-implications-for-personalized-medicine
#3
Deborah A Marshall, Juan Marcos Gonzalez, Karen V MacDonald, F Reed Johnson
We examine key study design challenges of using stated-preference methods to estimate the value of whole-genome sequencing (WGS) as a specific example of genomic testing. Assessing the value of WGS is complex because WGS provides multiple findings, some of which can be incidental in nature and unrelated to the specific health concerns that motivated the test. In addition, WGS results can include actionable findings (variants considered to be clinically useful and can be acted on), findings for which evidence for best clinical action is not available (variants considered clinically valid but do not meet as high of a standard for clinical usefulness), and findings of unknown significance...
January 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/28208811/does-the-valuation-of-nutritional-claims-differ-among-consumers-insights-from-spain
#4
Francesc Jurado, Azucena Gracia
The presence in the market of food products with nutritional claims is increasing. The objective of this paper is to assess consumers' valuation of some nutritional claims ('high in fiber' and 'reduced saturated fat') in a European country and to test for differences among consumers. An artefactual non-hypothetical experiment was carried out in a realistic setting (mock/real brick-and-mortar supermarket) with a sample of 121 Spanish consumers stratified by gender, age, and body mass index. A latent class model was specified and estimated with the data from the experiment...
February 13, 2017: Nutrients
https://www.readbyqxmd.com/read/28205149/making-implicit-assumptions-explicit-in-the-costing-of-informal-care-the-case-of-head-and-neck-cancer-in-ireland
#5
Paul Hanly, Rebecca Maguire, Myles Balfe, Eleanor O'Sullivan, Linda Sharp
BACKGROUND: From a health service perspective, informal care is often viewed as a potentially cost-effective way of transferring costs out of the formal healthcare sector. However, informal care is not a free resource. OBJECTIVE: Our objective was to assess the impact of alternative valuation methods and key assumptions on the cost of informal care. METHODS: Informal carers who assisted in the care of a head and neck cancer survivor for at least 1 year were sent a postal questionnaire during January-June 2014 requesting information on time spent on caring tasks in the month prior to the survey...
February 15, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/28199405/co-financing-for-viral-load-monitoring-during-the-course-of-antiretroviral-therapy-among-patients-with-hiv-aids-in-vietnam-a-contingent-valuation-survey
#6
Quyen Le Thi Nguyen, Long Hoang Nguyen, Bach Xuan Tran, Huong Thi Thu Phan, Huong Thi Le, Hinh Duc Nguyen, Tho Dinh Tran, Cuong Duy Do, Cuong Manh Nguyen, Vu Thi Minh Thuc, Carl Latkin, Melvyn W B Zhang, Roger C M Ho
BACKGROUND: Viral load testing is considered the gold standard for monitoring HIV treatment; however, given its high cost, some patients cannot afford viral load testing if this testing is not subsidized. Since foreign aid for HIV/AIDS in Vietnam is rapidly decreasing, we sought to assess willingness to pay (WTP) for viral load and CD4 cell count tests among HIV-positive patients, and identified factors that might inform future co-payment schemes. METHODS: A multi-site cross-sectional survey was conducted with 1133 HIV-positive patients on antiretroviral therapy (ART) in Hanoi and Nam Dinh...
2017: PloS One
https://www.readbyqxmd.com/read/28199176/handling-protest-responses-in-contingent-valuation-surveys
#7
Mark Pennington, Manuel Gomes, Cam Donaldson
OBJECTIVES: Protest responses, whereby respondents refuse to state the value they place on the health gain, are commonly encountered in contingent valuation (CV) studies, and they tend to be excluded from analyses. Such an approach will be biased if protesters differ from non-protesters on characteristics that predict their responses. The Heckman selection model has been commonly used to adjust for protesters, but its underlying assumptions may be implausible in this context. We present a multiple imputation (MI) approach to appropriately address protest responses in CV studies, and compare it with the Heckman selection model...
February 1, 2017: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/28196489/what-is-a-hospital-bed-day-worth-a-contingent-valuation-study-of-hospital-chief-executive-officers
#8
Katie Page, Adrain G Barnett, Nicholas Graves
BACKGROUND: Decreasing hospital length of stay, and so freeing up hospital beds, represents an important cost saving which is often used in economic evaluations. The savings need to be accurately quantified in order to make optimal health care resource allocation decisions. Traditionally the accounting cost of a bed is used. We argue instead that the economic cost of a bed day is the better value for making resource decisions, and we describe our valuation method and estimations for costing this important resource...
February 14, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28194657/eq-5d-and-the-euroqol-group-past-present-and-future
#9
REVIEW
Nancy J Devlin, Richard Brooks
Over the period 1987-1991 an inter-disciplinary five-country group developed the EuroQol instrument, a five-dimensional three-level generic measure subsequently termed the 'EQ-5D'. It was designed to measure and value health status. The salient features of its development and its consolidation and expansion are discussed. Initial expansion came, in particular, in the form of new language versions. Their development raised translation and semantic issues, experience with which helped feed into the design of two further instruments, the EQ-5D-5L and the youth version EQ-5D-Y...
February 13, 2017: Applied Health Economics and Health Policy
https://www.readbyqxmd.com/read/28186941/preference-based-disease-specific-health-related-quality-of-life-instrument-for-glaucoma-a-mixed-methods-study-protocol
#10
Sergei Muratov, Dominik W Podbielski, Susan M Jack, Iqbal Ike K Ahmed, Levine A H Mitchell, Monika Baltaziak, Feng Xie
INTRODUCTION: A primary objective of healthcare services is to improve patients' health and health-related quality of life (HRQoL). Glaucoma, which affects a substantial proportion of the world population, has a significant detrimental impact on HRQoL. Although there are a number of glaucoma-specific questionnaires to measure HRQoL, none is preference-based which prevent them from being used in health economic evaluation. The proposed study is aimed to develop a preference-based instrument that is capable of capturing important effects specific to glaucoma and treatments on HRQoL and is scored based on the patients' preferences...
November 8, 2016: BMJ Open
https://www.readbyqxmd.com/read/28155048/patient-versus-general-population-health-state-valuations-a-case-study-of-non-specific-low-back-pain
#11
J M van Dongen, B van denBerg, G E Bekkering, M W van Tulder, R W J G Ostelo
PURPOSE: The purpose of this study was twofold: (1) to compare non-specific low back pain (LBP) patients' health state valuations with those of the general population, and (2) to explore how aspects of health-related quality of life as measured by the EQ-5D-3L impact non-specific LBP patient valuations. METHODS: Data were used of a randomized controlled trial, including 483 non-specific LBP patients. Outcomes included the EQ-VAS and the EQ-5D-3L. Patient valuations were derived from the EQ-VAS...
February 2, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28152821/do-survivors-of-adolescent-and-young-adult-cancer-value-follow-up-cancer-care
#12
Eduardo Zamora, Rochelle Smits-Seemann, Kevin Boyle, Holly Perlman, Anne C Kirchhoff
: 8 Background: Survivors of adolescent and young adult (AYA) cancer, diagnosed between the ages of 15-39, require life-long medical care. Cost is a known barrier. However, survivors' valuation of follow-up care has not been investigated. We used willingness to pay (WTP), an economic tool for evaluating monetary values associated with medical services, to examine how survivors value follow-up care. METHODS: AYA cancer survivors ≥18 years of age who had completed their primary therapy were identified by the Utah Cancer Registry...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28148725/the-role-of-orbitofrontal-amygdala-interactions-in-updating-action-outcome-valuations-in-macaques
#13
Emily C Fiuzat, Sarah E V Rhodes, Elisabeth A Murray
: A previous study revealed that although monkeys with bilateral lesions of either the orbitofrontal cortex (OFC) or the amygdala could learn an action-outcome task, they could not adapt their choices in response to devalued outcomes. Specifically, they could not adjust their choice between two actions after the value of the outcome associated with one of the actions had decreased. Here we examined whether OFC needs to functionally interact with the amygdala inmediating such choices. Rhesus monkeys were trained to make two mutually exclusive actions on a touch-sensitive screen: 'tap' and 'hold'...
February 1, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28133977/health-state-utility-estimates-for-health-technology-assessment-a-review-of-the-manufacturers-submissions-to-the-french-national-authority-for-health
#14
Francoise F Hamers, Salah Ghabri, Catherine Le Gales
OBJECTIVES: To review the selection and methods used for deriving health state utility (HSU) estimates included in the cost-utility analyses (CUA) submitted by manufacturers to the National Authority for Health (HAS) during the first 2 years after the introduction of the economic evaluation for price setting in France. METHODS: We reviewed all manufacturers' submissions that included a CUA and were assessed by HAS by the end of October 2015 (N=34). We reviewed the identification, selection, and methods used to estimate HSU and compared them with those recommended by HAS...
January 29, 2017: Expert Review of Pharmacoeconomics & Outcomes Research
https://www.readbyqxmd.com/read/28124280/health-literacy-and-logical-inconsistencies-in-valuations-of-hypothetical-health-states-results-from-the-canadian-eq-5d-5l-valuation-study
#15
Fatima Al Sayah, Jeffrey A Johnson, Arto Ohinmaa, Feng Xie, Nick Bansback
OBJECTIVES: To examine the association of health literacy with logical inconsistencies in time trade-off valuations of hypothetical health states described by the EQ-5D-5L classification system. METHODS: Data from the EQ-5D-5L Canadian Valuation study were used. Health literacy was assessed using the Brief Health Literacy Screen. A health state valuation was considered logically inconsistent if a respondent gave the same or lower value for a very mild health state compared to the value given to 55555, or gave the same or lower value for a very mild health state compared to value assigned to the majority of the health states that are dominated by the very mild health state...
January 25, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28122626/developing-a-dementia-specific-health-state-classification-system-for-a-new-preference-based-instrument-ad-5d
#16
Kim-Huong Nguyen, Brendan Mulhern, Sanjeewa Kularatna, Joshua Byrnes, Wendy Moyle, Tracy Comans
BACKGROUND: With an ageing population, the number of people with dementia is rising. The economic impact on the health care system is considerable and new treatment methods and approaches to dementia care must be cost effective. Economic evaluation requires valid patient reported outcome measures, and this study aims to develop a dementia-specific health state classification system based on the Quality of Life for Alzheimer's disease (QOL-AD) instrument (nursing home version). This classification system will subsequently be valued to generate a preference-based measure for use in the economic evaluation of interventions for people with dementia...
January 25, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28118847/the-humanistic-and-economic-burden-of-chronic-wounds-a-protocol-for-a-systematic-review
#17
Krister Järbrink, Gao Ni, Henrik Sönnergren, Artur Schmidtchen, Caroline Pang, Ram Bajpai, Josip Car
BACKGROUND: Chronic non-healing wounds present a substantial economic burden to healthcare system; significant reductions in quality of life for those affected, and precede often serious events such as limp amputations or even premature deaths. This burden is also likely to increase with a larger proportion of elderly and increasing prevalence of life-style diseases such as obesity and diabetes. Reviews of the evidence on the burden of illness associated with chronic wounds have not been comprehensive in scope and have not provided an assessment of the distribution of the health care costs across categories of resource use...
January 24, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28112585/pharmacogenomics-testing-in-a-community-pharmacy-patient-perceptions-and-willingness-to-pay
#18
Mara L Gibson, Kenneth C Hohmeier, Cindy T Smith
AIM: To determine patient knowledge, interest and willingness-to-pay for pharmacogenomics testing in a community pharmacy. PATIENTS & METHODS: The link to a cross-sectional, anonymous online survey was distributed to a convenience sample of patients. The contingent valuation method was used to assess willingness-to-pay. RESULTS: Twenty seven surveys were completed. Eighty one percent of patients were interested in the service, but patients felt that they would be more likely to use the service if insurance covered the cost...
February 2017: Pharmacogenomics
https://www.readbyqxmd.com/read/28077722/higher-heart-rate-variability-is-associated-with-ventromedial-prefrontal-cortex-activity-and-increased-resistance-to-temptation-in-dietary-self-control-challenges
#19
Silvia U Maier, Todd A Hare
: Higher levels of self-control in decision making have been linked to better psychosocial and physical health. A similar link to health outcomes has been reported for heart-rate variability (HRV), a marker of physiological flexibility. Here, we sought to link these two, largely separate, research domains by testing the hypothesis that greater HRV would be associated with better dietary self-control in humans. Specifically, we examined whether total HRV at sedentary rest (measured as the SD of normal-to-normal intervals) can serve as a biomarker for the neurophysiological adaptability that putatively underlies self-controlled behavior...
January 11, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28075579/human-health-and-economic-impacts-of-ozone-reductions-by-income-group
#20
Rebecca K Saari, Tammy M Thompson, Noelle E Selin
Low-income households may be disproportionately affected by ozone pollution and ozone policy. We quantify how three factors affect the relative benefits of ozone policies with household income: (1) unequal ozone reductions; (2) policy delay; and (3) economic valuation methods. We model ozone concentrations under baseline and policy conditions across the full continental United States to estimate the distribution of ozone-related health impacts across nine income groups. We enhance an economic model to include these impacts across household income categories, and present its first application to evaluate the benefits of ozone reductions for low-income households...
February 8, 2017: Environmental Science & Technology
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