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Prenatal probiotics

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https://www.readbyqxmd.com/read/28571654/is-nutrient-content-and-other-label-information-for-prescription-prenatal-supplements-different-from-nonprescription-products
#1
Leila G Saldanha, Johanna T Dwyer, Karen W Andrews, LaVerne L Brown, Rebecca B Costello, Abby G Ershow, Pavel A Gusev, Constance J Hardy, Pamela R Pehrsson
BACKGROUND: Prenatal supplements are often recommended to pregnant women to help meet their nutrient needs. Many products are available, making it difficult to choose a suitable supplement because little is known about their labeling and contents to evaluate their appropriateness. OBJECTIVE: To determine differences between prescription and nonprescription prenatal supplements available in the United States regarding declared nutrient and nonnutrient ingredients and the presence of dosing and safety-related information...
May 29, 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/28471478/probiotics-for-the-prevention-of-necrotizing-enterocolitis-in-very-low-birth-weight-infants-a-meta-analysis-and-systematic-review
#2
REVIEW
John P Thomas, Tim Raine, Sanath Reddy, Gusztav Belteki
We performed an updated meta-analysis incorporating the results of recent randomised controlled trials (RCTs) to measure the effectiveness of probiotic supplementation in preventing necrotizing enterocolitis (NEC) and death in very-low-birth-weight (VLBW) infants, and to investigate any differences in efficacy by probiotic agent. Using meta-regression analysis, we assessed the contribution of other measured variables on the overall effect size and between-study variability. CONCLUSION: Overall, probiotics lead to significant reductions in NEC incidence and mortality in VLBW infants...
May 4, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28346920/microbial-composition-of-the-initial-colonization-of-newborns
#3
Samuli Rautava
Early-life interaction with indigenous intestinal microbes is a prerequisite for healthy immune and metabolic maturation. Human infants acquire their gut microbiota predominantly from the mother. A considerable inoculum of microbes is received by the neonate during vaginal delivery. Recent observations suggest that human gut colonization may be initiated prenatally by microbes in amniotic fluid, but the significance of this phenomenon remains unknown. After birth, neonatal gut colonization is guided by human milk factors, which selectively promote the growth of specific microbes, as well as by live microbes present in human milk...
2017: Nestlé Nutrition Institute Workshop Series
https://www.readbyqxmd.com/read/27968929/nutrition-and-skin-kids-are-not-just-little-people
#4
REVIEW
Meagen McCusker, Robert Sidbury
There has been a surge of new data regarding the pathophysiology of skin diseases. We are appreciating the sophisticated interplay among the skin, the immune system, and the environment. More elegant and highly specific medicines have been designed to target certain immune mediators of the adaptive immune system. In parallel fashion, we are learning more about the elegance of the innate immune system and how nutrition as early as the prenatal period can affect the priming of other immune cells. Concerns about the long-term impact of new immune-modulating medicines-especially in the pediatric population-have patients asking their dermatologists for nutritional alternatives to medical therapies...
November 2016: Clinics in Dermatology
https://www.readbyqxmd.com/read/27940670/environmental-enteric-dysfunction-and-growth-failure-stunting-in-global-child-health
#5
REVIEW
Victor Owino, Tahmeed Ahmed, Michael Freemark, Paul Kelly, Alexander Loy, Mark Manary, Cornelia Loechl
Approximately 25% of the world's children aged <5 years have stunted growth, which is associated with increased mortality, cognitive dysfunction, and loss of productivity. Reducing by 40% the number of stunted children is a global target for 2030. The pathogenesis of stunting is poorly understood. Prenatal and postnatal nutritional deficits and enteric and systemic infections clearly contribute, but recent findings implicate a central role for environmental enteric dysfunction (EED), a generalized disturbance of small intestinal structure and function found at a high prevalence in children living under unsanitary conditions...
December 2016: Pediatrics
https://www.readbyqxmd.com/read/27868221/what-s-new-in-atopic-eczema-an-analysis-of-systematic-reviews-published-in-2014-part-2-treatment-and-prevention
#6
REVIEW
A Lloyd-Lavery, N K Rogers, S J Hatfield, D Grindlay, R Barnett, K S Thomas
This review forms part of a series of annual updates that summarize the evidence base for atopic eczema (AE). It provides a summary of key findings from 12 systematic reviews (SRs) that were published or indexed during 2014, and focuses on the treatment and prevention of AE. For an update of SRs on the epidemiology, mechanisms of disease and methodological issues, see Part 1 of this update. Although phototherapy and various systemic medications (including ciclosporin, azathioprine and methotrexate) are commonly used to treat AE, many of these have not been robustly assessed in head-to-head randomized controlled trials...
January 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27696418/impact-of-a-novel-synbiotic-supplementation-during-gestation-and-lactation-on-immune-responses-in-the-swiss-albino-mice-offspring
#7
Himaja Nallagatla, Rajkumar Hemalatha, Narendra Babu Kondapalli, Shujauddin Mohammed
BACKGROUND: Prebiotics from various regularly consumed cereals and novel substrates are currently being utilised as functional foods. The aim of this study was to determine the effect of synbiotic, formulated with prebiotic extracted from natural resources like green gram (Vigna radiata) along with probiotic Lactobacillus rhamnosus GG (LGG) in modulating immune responses in the offspring when supplemented during gestation and lactation. RESULTS: Synbiotic supplementation was effective in improving cell mediated immunity and humoral immunity among F0 dams...
October 3, 2016: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/27661618/community-pharmacists-views-and-practices-regarding-natural-health-products-sold-in-community-pharmacies
#8
Ubaka Ogbogu, Candace Necyk
BACKGROUND: Reports of regulatory and evidentiary gaps have raised concerns about the marketing and use of natural health products (NHPs). The majority of NHPs offered for sale are purchased at a community pharmacy and pharmacists are "front-line" health professionals involved in the marketing and provision of NHPs. To date, the involvement of pharmacists in pharmacy care involving NHPs and the degree to which concerns over the safety, efficacy, marketing and regulation of NHPs are addressed in pharmacy care in Canada have not been studied...
2016: PloS One
https://www.readbyqxmd.com/read/27417220/environmental-risk-factors-and-their-role-in-the-management-of-atopic-dermatitis
#9
REVIEW
Robert Kantor, Jonathan I Silverberg
The etiology of atopic dermatitis (AD) is multifactorial with interaction between genetics, immune and environmental factors. Areas covered: We review the role of prenatal exposures, irritants and pruritogens, pathogens, climate factors, including temperature, humidity, ultraviolet radiation, outdoor and indoor air pollutants, tobacco smoke exposure, water hardness, urban vs. rural living, diet, breastfeeding, probiotics and prebiotics on AD. Expert commentary: The increased global prevalence of AD cannot be attributed to genetics alone, suggesting that evolving environmental exposures may trigger and/or flare disease in predisposed individuals...
January 2017: Expert Review of Clinical Immunology
https://www.readbyqxmd.com/read/27416628/dietary-strategies-for-primary-prevention-of-atopic-diseases-what-do-we-know
#10
REVIEW
Anna Lis-Święty, Dorota Milewska-Wróbel, Irmina Janicka
The paper refers to the recently published empirical data and systematic reviews on the impact of diets, foods, nutrients and bioactive substance exposures in pregnancy and in early infancy, on the development of atopic disorders. The results of studies referring to a broad range on dietary factors are mostly conflicting. There are several limitations of these researches. Based on the existing information, it is not possible to establish the role of antioxidants and vitamin D supplementation in atopic disease development...
January 2016: Developmental Period Medicine
https://www.readbyqxmd.com/read/26937896/probiotics-for-prevention-of-atopy-and-food-hypersensitivity-in-early-childhood-a-prisma-compliant-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#11
REVIEW
Guo-Qiang Zhang, Hua-Jian Hu, Chuan-Yang Liu, Qiao Zhang, Shristi Shakya, Zhong-Yue Li
Most studies investigated probiotics on food hypersensitivity, not on oral food challenge confirmed food allergy in children. The authors systematically reviewed the literature to investigate whether probiotic supplementation prenatally and/or postnatally could reduce the risk of atopy and food hypersensitivity in young children.PubMed, Embase, the Cochrane Central Register of Controlled Trials, and 4 main Chinese literature databases (Wan Fang, VIP, China National Knowledge Infrastructure, and SinoMed) were searched for randomized controlled trials regarding the effect of probiotics on the prevention of allergy in children...
February 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/26909656/epigenome-microbiome-crosstalk-a-potential-new-paradigm-influencing-neonatal-susceptibility-to-disease
#12
Rene Cortese, Lei Lu, Yueyue Yu, Douglas Ruden, Erika C Claud
Preterm birth is the leading cause of infant morbidity and mortality. Necrotizing enterocolitis (NEC) is an inflammatory bowel disease affecting primarily premature infants, which can be lethal. Microbial intestinal colonization may alter epigenetic signatures of the immature gut establishing inflammatory and barrier properties predisposing to the development of NEC. We hypothesize that a crosstalk exists between the epigenome of the host and the initial intestinal colonizing microbiota at critical neonatal stages...
March 3, 2016: Epigenetics: Official Journal of the DNA Methylation Society
https://www.readbyqxmd.com/read/26725748/risk-factors-in-autism-thinking-outside-the-brain
#13
REVIEW
Lauren Matelski, Judy Van de Water
Autism spectrum disorders (ASD) are complex neurodevelopmental conditions that have been rising markedly in prevalence for the past 30 years, now thought to affect 1 in 68 in the United States. This has prompted the search for possible explanations, and has even resulted in some controversy regarding the "true" prevalence of autism. ASD are influenced by a variety of genetic, environmental, and possibly immunological factors that act during critical periods to alter key developmental processes. This can affect multiple systems and manifests as the social and behavioral deficits that define these disorders...
February 2016: Journal of Autoimmunity
https://www.readbyqxmd.com/read/26689229/probiotics-for-allergy-prevention
#14
REVIEW
C E West
Probiotics, given either as a supplement or in infant foods, have been evaluated in randomised controlled trials for allergy prevention. Here, the aim is to give an overview of the results from these primary prevention studies and to discuss current strategies. In most studies, single strains or a mixture of strains of lactic acid bacteria and bifidobacteria have been used--prenatally, postnatally or perinatally. Several meta-analyses have reported a moderate benefit of probiotics for eczema prevention, and the most consistent effect has been observed with a combined perinatal intervention in infants at high risk of allergic disease due to familial predisposition...
2016: Beneficial Microbes
https://www.readbyqxmd.com/read/26645351/lactobacillus-rhamnosus-gg-supplementation-during-critical-windows-of-gestation-influences-immune-phenotype-in-swiss-albino-mice-offspring
#15
N Himaja, R Hemalatha, K Narendra Babu, M Shujauddin
Probiotic supplementation during critical windows of gestation might have a significant influence on the infant's immune phenotype. Swiss albino mice (F0 generation) aged 31 days were supplemented orally with probiotic Lactobacillus rhamnosus GG (LGG); and the supplementation was continued throughout mating, gestation and lactation. The pups (F1 generation) born to them were separated post weaning and received either the same probiotic supplementation as their mothers or were denied supplementation postnatally...
2016: Beneficial Microbes
https://www.readbyqxmd.com/read/26472040/supplement-use-by-women-during-pregnancy-data-from-the-massachusetts-general-hospital-national-pregnancy-registry-for-atypical-antipsychotics
#16
Marlene P Freeman, Alexandra Z Sosinsky, Danna Moustafa, Adele C Viguera, Lee S Cohen
Women of reproductive age commonly use integrative treatments. However, the reproductive safety for most complementary products lacks systematic study. We aimed to study the use of supplements by women in a prospective pregnancy registry. The Massachusetts General Hospital National Pregnancy Registry for Atypical Antipsychotics was established to evaluate the reproductive safety of atypical antipsychotics. Exposed and control participants were systematically queried about the use of vitamins and supplements...
June 2016: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/26413489/early-probiotics-to-prevent-childhood-metabolic-syndrome-a-systematic-review
#17
Haribalakrishna Balasubramanian, Sanjay Patole
AIM: To conduct a systematic review of studies on early probiotic supplementation to prevent childhood metabolic syndrome (MS). METHODS: Using the Cochrane systematic review strategy we searched PubMed, EMBASE, CENTRAL, CINAHL, and the conference proceedings of the Pediatric American Society meetings and trial registries in December 2014. Randomised controlled trials (RCTs) and non RCTs of probiotic supplementation to the mother and/or infant for a minimum duration of 4 wk were selected...
September 26, 2015: World Journal of Methodology
https://www.readbyqxmd.com/read/26175488/potential-role-of-the-intestinal-microbiota-in-programming-health-and-disease
#18
REVIEW
Olivier Goulet
The composition of the microbiota varies according to prenatal events, delivery methods, infant feeding, infant care environment, and antibiotic use. Postnatal gut function and immune development are largely influenced by the intestinal microbiota. Emerging evidence has shown that early microbiota colonization may influence the occurrence of later diseases (microbial programming). The vast majority of microbial species (commensals) give rise to symbiotic host-bacterial interactions that are fundamental for human health...
August 2015: Nutrition Reviews
https://www.readbyqxmd.com/read/25391939/gut-brain-link-grabs-neuroscientists
#19
Sara Reardon
No abstract text is available yet for this article.
November 13, 2014: Nature
https://www.readbyqxmd.com/read/25264881/probiotics-preventive-effect-on-pediatric-food-allergy-a-meta-analysis-of-randomized-controlled-trials
#20
Xiang-yi Kong, Yi Yang, Jian Guan, Ren-zhi Wang
OBJECTIVE: To investigate the preventive effect of probiotics on pediatric food allergy. METHODS: From MEDLINE bibliographical database, we searched and reviewed all randomized controlled trials on the preventive effects of probiotics on pediatric food allergies up to September 2013 and excluded the studies that do not meet inclusion criteria and extracted the data. Meta-analysis for the results of homogenous studies was performed using RevMan 5.0 and the co-effect was pooled by using fixed-effects model of relative risk (RR) ratios...
September 2014: Chinese Medical Sciences Journal, Chung-kuo i Hsüeh K'o Hsüeh Tsa Chih
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