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Cardio-vascular

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https://www.readbyqxmd.com/read/29226654/evaluation-of-hepcidin-and-atherosclerosis-in-dialysis-patients
#1
Victor Manolov, Julia Petrova, Boris Bogov, Savina Hadjidekova, Vasil Vasilev, Dyana Yonova, Maria Petrova, Todor Kunchev, Yavor Jelev, Petar Jeliazkov, Borislav Marinov, Ivo Bogov, Zlatina Gramatikova, Silviya Voleva, Kamen Tzatchev, Latchezar Traykov
BACKGROUND: Chronic kidney disease (CKD) is a condition that involves 10% - 15% of population worldwide, which increases the risk of cardio-vascular diseases (CVD). Chronic kidney disease is one of the main reasons for illness and mortality in the world. Chronic kidney disease is a serious health problem caused by involvement of a large number of patients with kidney injury, especially in industrial countries. Among the main reasons for this are population living longer and the number of diseases in elderly persons, such as diabetes mellitus type 2, hypertension, and cardio-vascular diseases...
November 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/29217959/periodontal-therapy-with-0-25-lemongrass-oil-mouthwash-in-reducing-risk-of-cardiovascular-diseases-a-3-arm-prospective-parallel-experimental-study
#2
Dany S Subha, Tangde Pradeep
Background: Periodontal disease is associated with cardiovascular diseases because of its role in host immune-inflammatory response. Serum lipids are the commonest risk factors between periodontal disease and cardiovascular diseases. Materials and Method: A double blinded randomised clinical trial was carried out among 45 subjects with generalised severe periodontitis. They were divided into 3-groups of 15 subjects each. Group A: 0.25% lemongrass oil mouthwash, Group B: 0...
September 2017: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/29203043/-blood-pressure-target-in-2017
#3
A Yannoutsos, A Bura-Rivière, P Priollet, J Blacher
OBJECTIVE: The issue of how far blood pressure (BP) should be lowered under antihypertensive treatment is still an important matter of scientific debate. The aim of the present review is to consider the clinical relevance of individualized BP goal under treatment in hypertensive patients according to their age, comorbidities or established cardio-vascular (CV) disease. DATA FROM THE LITERATURE: The French and European recommendations propose a systolic BP target between 130 and 139mmHg (<150mmHg after 80 years) and diastolic BP target <90mmHg in hypertensive patients whatever their level of risk...
December 2017: Journal de Médecine Vasculaire
https://www.readbyqxmd.com/read/29201112/association-of-warfarin-therapy-with-apoe-and-vkorc1-genes-polymorphism-in-iranian-population
#4
Sajad Rafiee, Masoumeh Rajabibazl, Reza Meshkani, Azam Daraei, Mehryar Zargari, Fahimeh Sharafeddin, Zahra Fazeli, Attabak Toffani Milani, Maryam Taherkhani
Warfarin is a vitamin K antagonist that genetic and non-genetic factors affected on its dose requirement in the patients with cardio vascular disease. The aim of this study was whether the APOE and VKORC1 polymorphisms influence on warfarin dose requirements in the part of Iranian patients. Blood samples were collected from 86 warfarin-treated patients. After extraction of genomic DNA, the VKORC1 (rs9923231) and the APOE (rs429358 and rs7412) polymorphisms were genotyped by PCR-RFLP technique. We found that the Iranian patients carrying genotypes GA or AA of VKORC1 polymorphism tended to receive lower dose of warfarin (p = 0...
2017: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/29197746/proton-therapy-for-locally-advanced-breast-cancer-a-systematic-review-of-the-literature
#5
REVIEW
Emmanuel Kammerer, Jennifer Le Guevelou, Abdulhamid Chaikh, Serge Danhier, Julien Geffrelot, Christelle Levy, Eric Saloux, Jean-Louis Habrand, Juliette Thariat
BACKGROUND: Radiation therapy plays a major role in the management of adjuvant breast cancer with nodal involvement, with an iatrogenic increase of cardio-vascular risk. Photon therapy, even with intensity modulation, has the downsides of high mean heart dose and heterogeneous target coverage, particularly in the case of internal mammary irradiation. This systematic review of the literature aims to evaluate proton therapy in locally advanced breast cancer. MATERIAL AND METHODS: PubMed was searched for original full-text articles with the following search terms: «Proton Therapy» and «Breast Cancer»...
November 24, 2017: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/29142443/oral-health-and-erectile-dysfunction
#6
REVIEW
Vijendra P Singh, Sunil K Nettemu, Sowmya Nettem, Rajesh Hosadurga, Sangeeta U Nayak
Ample evidence strongly supports the fact that periodontal disease is a major risk factor for various systemic diseases namely cardio-vascular disease, diabetes mellitus, etc. Recently, investigators focussed on exploring the link between chronic periodontitis (CP) and erectile dysfunction (ED) by contributing to the endothelial dysfunction. Both the diseases share common risk factors. Various studies conducted in different parts of the world in recent years reported the evidence linking this relationship as well as improvement in ED with periodontal treatment...
July 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29141542/cocoa-polyphenols-evidence-from-epidemiological-studies
#7
Chisa Matsumoto
BACKGROUND: Accumulating evidence suggests potential preventive effects of chocolate/cocoa on the risk of cardio vascular disease (CVD). However, cocoa products also contain high levels of sugar and fat, which increase CVD risk factors. Even, the identity of the substance in chocolate/cocoa that has a favorable effect on CVD and CVD risk factors remains unclear, growing evidence from experimental studies suggests that cocoa polyphenols might be a major contributor to cardiovascular-protective effects...
November 14, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29096858/management-of-patients-with-statin-intolerance
#8
Sabine Fischer, Ulrich Julius
In recent years statins have become an established option in lipid-lowering pharmacotherapy despite the fact that statin intolerance is fairly common. When muscle pains and/or an elevation of the creatine kinase appear, the dose must be lowered in patients with slight symptoms or stopped altogether if the symptoms are more severe. When the symptoms are alleviated and creatine kinase is normalized, re-exposition can be considered. If symptoms recur, treatment with another statin should be attempted - in these cases pravastatin or fluvastatin are recommended, although they are less effective in reducing LDL cholesterol...
November 2017: Atherosclerosis. Supplements
https://www.readbyqxmd.com/read/29072174/blood-lipid-tests-in-2017
#9
Rémy Couderc, Marianne Antar, Dominique Bonnefont-Rousselot, Jean-Louis Paul, Patrice Therond
Strong epidemiological evidence supports a causal relationship between dyslipidemia and atherosclerotic cardio-vascular disease, which remains the leading cause of death and morbidity worldwide. A lipid profile (total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides) is recommended at the initial evaluation for the assessment of the cardio-vascular risk. A commentary of the lipid profile for the clinician and mostly for the patient should be stated on the lab report. Quantifying the cardio-vascular risk using the SCORE (systematic coronary risk estimation) system, as recommended by the Haute autorité de santé (HAS), is the starting point to establish therapeutic goals and treatment strategies...
October 26, 2017: Annales de Biologie Clinique
https://www.readbyqxmd.com/read/29064812/-the-influence-of-drugs-used-in-the-treatment-of-diabetes-type-2-on-the-cardio-vascular-risk
#10
Adam Kern, Martyna Zaleska, Olga Możeńska, Jacek Bil
With the obesity epidemic, we observe increase in the number of people suffering from diabetes mellitus type 2. This illness is considered cardiovascular disease equivalent, so influence of drugs used to manage diabetes on cardiovascular outcomes is important. Below we present review of main class of drugs used in diabetes treatment and summingup of trials conducted with their use to evaluate cardiovascular risk during treatment.
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29064196/-a-palliative-care-approach-of-patients-with-chronic-obstructive-pulmonary-disease
#11
Lisa Hentsch, Sebastian Carballo, Jean-Paul Janssens, Layla Ossmann, Sophie Pautex
Chronic obstructive pulmonary disease (COPD) is a frequent, progressive and lethal disease. As opposed to other chronic illnesses, such as cardio-vascular diseases, the prevalence of COPD is still on the rise. It is now well documented that these patients can present many invalidating symptoms towards the end of their life. The aim of a palliative approach for patients living with advanced COPD is to decrease the impact of symptoms and offer a pluridisciplinary approach so as to maintain the best possible quality of life...
October 18, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29037887/depression-and-related-risk-factors-among-patients-with-type-2-diabetes-mellitus-jazan-area-ksa-a-cross-sectional-study
#12
Osama B Albasheer, Mohammed S Mahfouz, Yahia Solan, Duaa A Khan, Mohammed A Muqri, Haneen A Almutairi, Ali M Alelyani, Hussain A Alahmed
PURPOSE: To determine the prevalence of depression and related risk factors among type 2 diabetes mellitus patients (T2DM) in Jazan area, Saudi Arabia. METHOD: A cross sectional, self-administered questionnaire study was conducted among T2DM patients in Jazan area, Saudi Arabia. A total of 385 patients were selected at randomly. The Patient Health Questionnaire (PHQ-9) was utilized to measure symptoms and signs of depression. RESULTS: The overall prevalence of depression among T2DM patients was 37...
September 28, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29026289/can-we-predict-postoperative-complications-in-elderly-chinese-patients-with-hip-fractures-using-the-surgical-risk-calculator
#13
Xiao Wang, Bin Jiang Zhao, Yue Su
PURPOSE: Hip fractures are associated with poor prognosis in elderly patients partly due to the high rate of postoperative complications. This study was aimed to investigate whether the surgical risk calculator is suitable for predicting postoperative complications in elderly Chinese patients with hip fractures. METHODS: The incidence of postoperative complications among 410 elderly patients with hip fractures was predicted by the surgical risk calculator and then compared with the actual value...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29017680/carotid-intima-media-thickness-percentiles-for-pakistani-population
#14
Waseem Mirza, Mubashir Aslam Arain, Arif Ali, Vaqar Bari, Mirza Kazim Ali, Kainat Fatima
Carotid artery intima media thickness estimation is a well-established way of cardio vascular disease evaluation. The purpose of this cross-sectional study was to develop normal carotid intima media thickness percentile values for a Pakistani cohort. Data was collected at the Departments of Radiology and Family Medicine, The Aga Khan University Hospital, Karachi, from April 2014 to August 2015. High frequency ultrasound of carotid was done in 257 patients [97 male (38%), 160 female (62%)] without any known carotid artery disease...
September 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29017156/the-missing-link-in-the-pathophysiology-of-vascular-cognitive-impairment-design-of-the-heart-brain-study
#15
Astrid M Hooghiemstra, Anne Suzanne Bertens, Anna E Leeuwis, Esther E Bron, Michiel L Bots, Hans-Peter Brunner-La Rocca, Anton J M de Craen, Rob J van der Geest, Jacoba P Greving, L Jaap Kappelle, Wiro J Niessen, Robert J van Oostenbrugge, Matthias J P van Osch, Albert de Roos, Albert C van Rossum, Geert Jan Biessels, Mark A van Buchem, Mat J A P Daemen, Wiesje M van der Flier
BACKGROUND: Hemodynamic balance in the heart-brain axis is increasingly recognized as a crucial factor in maintaining functional and structural integrity of the brain and thereby cognitive functioning. Patients with heart failure (HF), carotid occlusive disease (COD), and vascular cognitive impairment (VCI) present themselves with complaints attributed to specific parts of the heart-brain axis, but hemodynamic changes often go beyond the part of the axis for which they primarily seek medical advice...
October 10, 2017: Cerebrovascular Diseases Extra
https://www.readbyqxmd.com/read/28981241/-lipid-lowering-therapy-in-the-elderly
#16
E Schils
During the last decade, life expectancy increased in western countries. Among the elderly, cardiovascular diseases are still the leading cause of death. In both genders, cardiovascular risk increases with age. The statistical correlation between total cholesterol level and mortality is less substantial with age, yet it still exists. Clinical studies have shown the clinical benefit of statin therapy, both in terms of cardio-vascular events and survival in the elderly population. The use of statins in elderly patients can currently be recommended for secondary prevention...
2017: Revue Médicale de Bruxelles
https://www.readbyqxmd.com/read/28963830/-uremic-toxins-how-can-we-improve-the-removal-today
#17
REVIEW
Ugo Teatini, Giorgio Romei Longhena
Uremic status results from a malfunctioning of kidneys due to the accumulation of compounds which, under normal conditions, are excreted or metabolized by the kidneys. If these compounds are biologically active, they are called uremic toxins. Such compounds have toxic effects on the cardio-vascular system. An useful classification, published by the European Uremic Toxin Work Group (EUTox) is: 1) small water-soluble compounds; 2) protein-bound compounds; 3) the larger "middle molecules". High-flux membranes and more efficient treatment techniques, like HDF, improve the removal of uremic toxins in the middle molecular-weight range, and recent studies suggest that these strategies have better results on the morbidity and mortality...
September 28, 2017: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/28923026/dementia-and-cognitive-disorder-identified-at-a-forensic-psychiatric-examination-a-study-from-sweden
#18
Anette Ekström, Marianne Kristiansson, Karin Sparring Björkstén
BACKGROUND: Few studies have addressed the relationship between dementia and crime. We conducted a study of persons who got a primary or secondary diagnosis of dementia or cognitive disorder in a forensic psychiatric examination. METHODS: In Sweden, annually about 500 forensic psychiatric examinations are carried out. All cases from 2008 to 2010 with the diagnoses dementia or cognitive disorder were selected from the database of the Swedish National Board of Forensic Medicine...
September 18, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28919930/effects-of-12-weeks-of-nordic-walking-and-xco-walking-training-on-the-endurance-capacity-of-older-adults
#19
Tobias Morat, Jenny Krueger, Angus Gaedtke, Manuela Preuss, Joachim Latsch, Hans-Georg Predel
BACKGROUND: Several studies have already examined the positive effects of various forms of endurance training in patient groups and in healthy adults up to 60 years old. The aim of this study was to analyse the effects of Nordic Walking (NW) and XCO Walking (XCO) training on endurance capacity in healthy older adults, aged 60 years and older. METHODS: Twenty-three older participants (mean age: 69.9 ± 5.4 years) were randomly assigned to either the NW group or the XCO group...
2017: European Review of Aging and Physical Activity
https://www.readbyqxmd.com/read/28894045/neopterin-as-a-marker-of-cellular-immunological-response
#20
Łukasz Michalak, Magdalena Bulska, Karolina Strząbała, Piotr Szcześniak
Neopterin is a pyrazino-pyrimidine compound that belongs to the pteridine group. It is known to be a biochemical marker associated with cell-mediated immunity. It is produced by human monocytes/macrophages and dendritic cells from guanosine triphosphate (GTP) upon stimulation with interferon gamma (IFNγ), which is released by activated limphocytes Th. Neopterin is a very important clinic parameter, though the physiological role has not been exactly definited thus far. The level of neopterin reflects the stage of activation of the cellular immune system, which is important in the pathogenesis and progression of various diseases...
August 24, 2017: Postȩpy Higieny i Medycyny Doświadczalnej
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