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Cardio-vascular

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https://www.readbyqxmd.com/read/29914383/the-predictive-role-of-aortic-propagation-velocity-for-coronary-artery-disease
#1
Fereshteh Ghaderi, Hossein Samim, Faeze Keihanian, Seyed Ali Danesh Sani
BACKGROUND: It is well recognized that cardio- vascular risk factors lead to histological and functional changes in aorta, and aortic stiffness is the best predictor of cardiovascular morbidity and mortality. In this study we evaluated the relation of a less evaluated echocardiographic parameter of aortic stiffness, aortic propagation velocity (APV) with the presence and severity of CAD. METHODS: This cross sectional study was conducted from May 2015 to March 2016 in Imam Reza hospital, Mashhad, Iran...
June 19, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29913892/mortality-rate-and-causes-of-death-in-women-with-self-reported-musculoskeletal-pain-results-from-a-17-year-follow-up-study
#2
Anne K Nitter, Karin Ø Forseth
Aabstract Introduction Chronic musculoskeletal pain represents a significant health problem among adults in Norway. The prevalence of chronic pain is reported to be 35-53% in cross sectional studies of both genders. For many years, it has been a common opinion among medical doctors that chronic pain may indeed reduce a person's quality of life, but not affect life expectancy. However, over the previous two decades, reports about mortality and cause of death in individuals with chronic pain have been published...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29897460/pharmacokinetic-and-metabolic-studies-of-ginsenoside-rb3-in-rats-using-rrlc-q-tof-ms
#3
Lefeng Zhao, Yue Ma, Changbao Chen, Shuying Liu, Wei Wu
Ginsenoside Rb3 is one of major ginsenosides in Panax ginseng with effect on cardio-vascular and central nervous system. The aim of this study is to develop a rapid resolution liquid chromatography coupled with quadrupole-time-of-flight mass spectrometry (RRLC-Q-TOF-MS) method for pharmacokinetic study of ginsenoside Rb3 and simultaneous determination of metabolites in rats. The results showed that the concentration-time profile of ginsenoside Rb3 conformed to a two-compartment pharmacokinetic model after intravenous administration at the dosage of 2...
July 1, 2018: Journal of Chromatographic Science
https://www.readbyqxmd.com/read/29895722/deleting-death-and-dialysis-conservative-care-of-cardio-vascular-risk-and-kidney-function-loss-in-chronic-kidney-disease-ckd
#4
REVIEW
Raymond Vanholder, Steven Van Laecke, Griet Glorieux, Francis Verbeke, Esmeralda Castillo-Rodriguez, Alberto Ortiz
The uremic syndrome, which is the clinical expression of chronic kidney disease (CKD), is a complex amalgam of accelerated aging and organ dysfunctions, whereby cardio-vascular disease plays a capital role. In this narrative review, we offer a summary of the current conservative (medical) treatment options for cardio-vascular and overall morbidity and mortality risk in CKD. Since the progression of CKD is also associated with a higher cardio-vascular risk, we summarize the interventions that may prevent the progression of CKD as well...
June 12, 2018: Toxins
https://www.readbyqxmd.com/read/29878290/acute-coronary-syndrome-without-persistent-st-segment-elevation-in-the-emergency-department-epidemiology-clinical-features-and-prognosis
#5
Hanen Ghazali, Mouna Gammoudi, Anware Yahmadi, Aymen Zoubli, Ahlem Azouzi, Sami Souissi
BACKGROUND: Acute coronary syndrome without persistent ST segment elevation (NSTE-ACS) is a major public health problem. It has been the subject of numerous studies but little has been published from the emergency department (ED). OBJECTIVE: Describe the epidemiology, clinical features, management and prognosis of patients with NSTE-ACS presenting to ED. METHODS: Prospective, observational, over four years study (2011-2015). INCLUSION CRITERIA: patients (> 18 years of age) presenting consecutively to ED with the diagnosis of NSTE-ACS...
December 2017: La Tunisie Médicale
https://www.readbyqxmd.com/read/29870326/-long-term-statin-adherence-in-patients-with-stable-angina-after-coronary-stenting
#6
D I Tomilova, Y A Karpov, V V Lopukhova
PURPOSE: To study adherence to therapy with statins and its relation to development of cardio-vascular complications (CVC) in patients with stable angina after elective percutaneous coronary intervention (PCI) at five-year observation. MATERIALS AND METHODS: This study comprised 574 patients with stable angina (81 % men, mean age 60.3 years) hospitalized for elective PCI. All patients were prescribed therapy in accordance with recommendations on management of stable angina including statins...
May 2018: Kardiologiia
https://www.readbyqxmd.com/read/29793015/right-atrial-anomalous-muscle-bundle-presenting-with-acute-superior-vena-cava-syndrome-and-pulmonary-embolism-surgical-management
#7
Jeko M Madjarov, Michael G Katz, Sophia Madjarova, Svetozar Madzharov, Frank R Arko, David W Miller, Francis Robicsek
BACKGROUND: An anomalous muscle bundle crossing the right atrial cavity represents a pathological finding with unproved clinical significance. This congenital anomaly may be difficult to recognize via echocardiography and could be confused with other intra-cavitary lesions. METHODS: We report a case of a 53-year-old female presented to the cardio-vascular service with acute superior vena cava syndrome and sub-massive pulmonary embolism. RESULTS: The patient underwent venography confirming superior vena cava stenosis...
May 21, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29783249/prognosis-of-ischaemic-heart-disease-in-patients-with-newly-diagnosed-dm-type-2-by-logistic-regression
#8
Alina Urbanovych, Halyna Suslyk
OBJECTIVE: Introduction: Diabetes Mellitus (DM) type 2 is an important medical and social problem all around the world. One of the most serious and widespread complications of DM type 2 is a damage to the cardiovascular system. The aim was to study the way of how to predict the IHD development in patients with the newly diagnosed DM type 2 by building a mathematical model with the help of statistical method, in particular, a logistic regression, which allows predicting the occurrence of IHD by the levels of proven biochemical and anthropometric indices...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783221/hygienic-assessment-of-different-forms-of-physical-education-lessons-organization-in-primary-school
#9
Oleksandra S Kondratiuk, Maria M Korshun, Sergii I Garkavyi, Sergii S Garkavyi, Liudmyla A Stasiuk, Olena V Dema, Olga O Sokolovska
OBJECTIVE: Introduction: Different forms of physical education lessons organization, including swimming classes were introduced in education process without studying of its healthsaving effectiveness. The aim of this study was hygienic assessment of different forms of physical education lessons organization in primary school. PATIENTS AND METHODS: Materials and methods: Cross-sectional study was conducted in two schools with different organization of physical education lessons...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29782517/importance-of-software-version-for-measurement-of-arterial-stiffness-arteriograph-as-an-example
#10
Margareta Ring, Maria J Eriksson, Gunnar Nyberg, Kenneth Caidahl
BACKGROUND: Current guidelines recommend the measurement of arterial stiffness in terms of aortic pulse wave velocity (PWV) as an important cardio-vascular risk marker. Both aortic PWV and the aortic augmentation index (AIxao) can be measured using different techniques, e.g., the Arteriograph and SphygmoCor. A new version of the software for the Arteriograph (v. 3.0.0.1, TensioMed, Budapest, Hungary; Arteriograph II) is now available. We wanted to determine whether this improved software differs from the previous version (Arteriograph v...
2018: PloS One
https://www.readbyqxmd.com/read/29782289/-the-effect-of-changing-of-conventional-antihypertensive-therapy-to-a-triple-fixed-combination-therapy-with-rosuvastatin-in-high-cardiovascular-risk-patients
#11
F T Ageev, Z N Blankova, N S Samsonova
BACKGROUND: The low efficiency of recommended therapy for reducing cardiovascular risk (CV) in patients with arterial hypertension even with an effective blood pressure decrease is often due to the persistence of high blood cholesterol and arterial stiffness. Among the effective ways to achieve the goal of therapy is considered the changing to a single-pill combinations (SPCs) of two antihypertensive drugs and statin. AIM: To assess influence of fixed combination consisted of amlodipine, lisinopril and rosuvastatin to the dynamic of lipid spectrum, blood pressure level and elastic properties of arteries in patients with arterial hypertension and high risk of cardio-vascular complications being transferred from their preceding antihypertensive therapy...
2018: Kardiologiia
https://www.readbyqxmd.com/read/29748035/direct-correlation-between-serum-homocysteine-level-and-insulin-resistance-index-in-patients-with-subclinical-hypothyroidism-does-subclinical-hypothyroidism-increase-the-risk-of-diabetes-and-cardio-vascular-disease-together
#12
Anahita Ebrahimpour, Mostafa Vaghari-Tabari, Durdi Qujeq, Soheila Moein, Zoleikha Moazezi
BACKGROUND: Subclinical hypothyroidism known as mild thyroid disorder without significant sign and symptoms. The correlation between subclinical hypothyroidism and some of cardiovascular disease risk factors such as serum lipids, homocysteine levels and also insulin resistance index is not well established and the current study was conducted to clarify this issue. METHODS AND MATERIALS: Seventy four patients with mild elevation in levels of thyroid stimulating hormone (TSH) along with normal levels of T3 and T4 were selected as patients group and 74 age and sex matched individuals were selected as healthy control group...
May 5, 2018: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29730298/exploring-the-biophysical-properties-of-phytosterols-in-the-plasma-membrane-for-novel-cancer-prevention-strategies
#13
REVIEW
Omar Fakih, Didem Sanver, David Kane, James L Thorne
Cancer is a global problem with no sign that incidences are reducing. The great costs associated with curing cancer, through developing novel treatments and applying patented therapies, is an increasing burden to developed and developing nations alike. These financial and societal problems will be alleviated by research efforts into prevention, or treatments that utilise off-patent or repurposed agents. Phytosterols are natural components of the diet found in an array of seeds, nuts and vegetables and have been added to several consumer food products for the management of cardio-vascular disease through their ability to lower LDL-cholesterol levels...
May 3, 2018: Biochimie
https://www.readbyqxmd.com/read/29729156/correlations-between-lipid-metabolism-indices-in-patients-with-hypertension-and-hypothyroidism
#14
Lyubov V Olenych, Lesya I Pylypiv, Nataliya S Bek, Olena M Radchenko
OBJECTIVE: Introduction: Hypertension is a major reason behind morbidity, disability and mortality. Elevated blood pressure is a huge risk factor for cardio-vascular diseases. Almost 90% of hypertension patients have internal comorbidities, in particular hypothyroidism. For now, however, the specificities of the clinical course of hypertension in hypothyroid patients are understudied and the data on lipid metabolism in patients with primary hypothyroidism and hypertension are inconclusive...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29723920/association-between-hepatitis-c-infection-and-cerebro-cardiovascular-disease-analysis-of-a-national-population-based-survey-in-egypt
#15
Mohsen Gadallah, Sahar Kandil, Amira Mohsen
OBJECTIVES: To examine the association between Hepatitis C virus (HCV) infection, cardiovascular risk factors and cerebro-cardiovascular (CCV) disease. METHODS: The source of data was the Egypt Health Issues Survey conducted in 2015. Participants were 11,256 individuals with complete HCV testing, age 25-59 years. Data on demographics, cardio-vascular risk factors, CCV disease (myocardial infarction and/or cerebral stroke) and HCV infection were retrieved. Descriptive, bivariate, multivariable logistic regression and sensitivity analyses were performed to determine the independent association of past HCV exposure or chronic infection with diabetes, hypertension, and CCV disease...
May 3, 2018: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29715313/circulating-pentraxin-3-is-positively-associated-with-chronic-hyperglycemia-but-negatively-associated-with-plasma-aldosterone-concentration
#16
Yuichi Takashi, Minae Koga, Yoko Matsuzawa, Jun Saito, Masao Omura, Tetsuo Nishikawa
Pentraxin 3 (PTX3) is reported to be a vascular inflammation marker providing prognostic information of vasculopathy. Until today, however, the effect of aldosterone or oxidative stress on the regulation of PTX3 is unknown. In present study, we investigated to find regulative factors, especially aldosterone and oxidative stress, on PTX3. Serum PTX3 levels were measured in 75 patients (45 male and 30 women, aged 55.1±13.4 year-old (mean±SD)) with various endocrine disorders including 47 with diabetes, 24 with primary aldosteronism (PA)...
2018: PloS One
https://www.readbyqxmd.com/read/29695256/metabolic-distress-in-lipid-one-carbon-metabolic-pathway-through-low-vitamin-b-12-a-population-based-study-from-north-india
#17
Kallur Nava Saraswathy, Shipra Joshi, Suniti Yadav, Priyanka Rani Garg
BACKGROUND: Dyslipidemia and hyper-homocysteinemia are the major independent risk factors of cardio vascular disease. Deficiency of folate and vitamin B-12 are associated with both hyper-homocysteinemia and dyslipidemia. The aim of the study is to evaluate the relationship of homocysteine and its associated dietary determinant levels (Folate and Vitamin B-12) with lipids and obesity parameters (WC, BMI, WHR) in North Indian population. METHODS: The participants were recruited under a major government funded project through household survey covering 15 villages of Haryana, India...
April 25, 2018: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29672186/atherosclerosis-of-the-carotid-bulb-is-associated-with-the-severity-of-orthostatic-hypotension-in-non-diabetic-adult-patients-a-cross-sectional-study
#18
Yusuke Kobayashi, Hiroaki Ishiguro, Tetsuya Fujikawa, Hideo Kobayashi, Koichiro Sumida, Minako Kagimoto, Yuki Okuyama, Yosuke Ehara, Mari Katsumata, Megumi Fujita, Akira Fujiwara, Sanae Saka, Keisuke Yatsu, Nobuhito Hirawa, Yoshiyuki Toya, Gen Yasuda, Satoshi Umemura, Kouichi Tamura
BACKGROUND: The carotid bulb has a high density of baroreceptors that play an important role in maintaining blood pressure. We hypothesized that atherosclerosis of the carotid bulb would reflect the severity of orthostatic hypotension more accurately than would atherosclerosis of other carotid artery segments. METHODS: This cross-sectional study included 198 non-diabetic adults. We measured the cardio-vascular ankle index as an index of arterial stiffness, intima-media thickness in each carotid artery segment (internal carotid artery, carotid bulb, distal and proximal portions, respectively, of the common carotid artery) as a measure of atherosclerosis, and heart rate variability as a measure of cardiac autonomic function...
April 19, 2018: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/29661162/the-cold-pressor-test-in-interictal-migraine-patients-different-parasympathetic-pupillary-response-indicates-dysbalance-of-the-cranial-autonomic-nervous-system
#19
Ozan E Eren, Ruth Ruscheweyh, Christoph Schankin, Florian Schöberl, Andreas Straube
BACKGROUND: Data on autonomic nervous system (ANS) activations in migraine patients are quite controversial, with previous studies reporting over- and underactivation of the sympathetic as well as parasympathetic nervous system. In the present study, we explicitly aimed to assess the cranial ANS in migraine patients compared to healthy controls by applying the cold pressor test to a cohort of migraine patients in the interictal phase and measuring the pupillary response. METHODS: In this prospective observational study, a strong sympathetic stimulus was applied to 20 patients with episodic migraine in the interictal phase and 20 matched controls without migraine, whereby each participant dipped the left hand into ice-cold (4 °C) water for a maximum of 5 min (cold pressor test)...
April 16, 2018: BMC Neurology
https://www.readbyqxmd.com/read/29659479/oral-dysbiotic-communities-and-their-implications-in-systemic-diseases
#20
REVIEW
Preethi Sudhakara, Abishek Gupta, Anshumouli Bhardwaj, Aruni Wilson
The human body supports the growth of a wide array of microbial communities in various niches such as the oral cavity, gastro-intestinal and urogenital tracts, and on the surface of the skin. These host associated microbial communities include yet-un-cultivable bacteria and are influenced by various factors. Together, these communities of bacteria are referred to as the human microbiome. Human oral microbiome consists of both symbionts and pathobionts. Deviation from symbiosis among the bacterial community leads to “dysbiosis”, a state of community disturbance...
April 16, 2018: Dentistry journal
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