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Cardio-vascular

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https://www.readbyqxmd.com/read/29037887/depression-and-related-risk-factors-among-patients-with-type-2-diabetes-mellitus-jazan-area-ksa-a-cross-sectional-study
#1
Osama B Albasheer, Mohammed S Mahfouz, Yahia Solan, Duaa A Khan, Mohammed A Muqri, Haneen A Almutairi, Ali M Alelyani, Hussain A Alahmed
PURPOSE: To determine the prevalence of depression and related risk factors among type 2 diabetes mellitus patients (T2DM) in Jazan area, Saudi Arabia. METHOD: A cross sectional, self-administered questionnaire study was conducted among T2DM patients in Jazan area, Saudi Arabia. A total of 385 patients were selected at randomly. The Patient Health Questionnaire (PHQ-9) was utilized to measure symptoms and signs of depression. RESULTS: The overall prevalence of depression among T2DM patients was 37...
September 28, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29026289/can-we-predict-postoperative-complications-in-elderly-chinese-patients-with-hip-fractures-using-the-surgical-risk-calculator
#2
Xiao Wang, Bin Jiang Zhao, Yue Su
PURPOSE: Hip fractures are associated with poor prognosis in elderly patients partly due to the high rate of postoperative complications. This study was aimed to investigate whether the surgical risk calculator is suitable for predicting postoperative complications in elderly Chinese patients with hip fractures. METHODS: The incidence of postoperative complications among 410 elderly patients with hip fractures was predicted by the surgical risk calculator and then compared with the actual value...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29017680/carotid-intima-media-thickness-percentiles-for-pakistani-population
#3
Waseem Mirza, Mubashir Aslam Arain, Arif Ali, Vaqar Bari, Mirza Kazim Ali, Kainat Fatima
Carotid artery intima media thickness estimation is a well-established way of cardio vascular disease evaluation. The purpose of this cross-sectional study was to develop normal carotid intima media thickness percentile values for a Pakistani cohort. Data was collected at the Departments of Radiology and Family Medicine, The Aga Khan University Hospital, Karachi, from April 2014 to August 2015. High frequency ultrasound of carotid was done in 257 patients [97 male (38%), 160 female (62%)] without any known carotid artery disease...
September 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29017156/the-missing-link-in-the-pathophysiology-of-vascular-cognitive-impairment-design-of-the-heart-brain-study
#4
Astrid M Hooghiemstra, Anne Suzanne Bertens, Anna E Leeuwis, Esther E Bron, Michiel L Bots, Hans-Peter Brunner-La Rocca, Anton J M de Craen, Rob J van der Geest, Jacoba P Greving, L Jaap Kappelle, Wiro J Niessen, Robert J van Oostenbrugge, Matthias J P van Osch, Albert de Roos, Albert C van Rossum, Geert Jan Biessels, Mark A van Buchem, Mat J A P Daemen, Wiesje M van der Flier
BACKGROUND: Hemodynamic balance in the heart-brain axis is increasingly recognized as a crucial factor in maintaining functional and structural integrity of the brain and thereby cognitive functioning. Patients with heart failure (HF), carotid occlusive disease (COD), and vascular cognitive impairment (VCI) present themselves with complaints attributed to specific parts of the heart-brain axis, but hemodynamic changes often go beyond the part of the axis for which they primarily seek medical advice...
October 10, 2017: Cerebrovascular Diseases Extra
https://www.readbyqxmd.com/read/28981241/-lipid-lowering-therapy-in-the-elderly
#5
E Schils
During the last decade, life expectancy increased in western countries. Among the elderly, cardiovascular diseases are still the leading cause of death. In both genders, cardiovascular risk increases with age. The statistical correlation between total cholesterol level and mortality is less substantial with age, yet it still exists. Clinical studies have shown the clinical benefit of statin therapy, both in terms of cardio-vascular events and survival in the elderly population. The use of statins in elderly patients can currently be recommended for secondary prevention...
2017: Revue Médicale de Bruxelles
https://www.readbyqxmd.com/read/28963830/-uremic-toxins-how-can-we-improve-the-removal-today
#6
REVIEW
Ugo Teatini, Giorgio Romei Longhena
Uremic status results from a malfunctioning of kidneys due to the accumulation of compounds which, under normal conditions, are excreted or metabolized by the kidneys. If these compounds are biologically active, they are called uremic toxins. Such compounds have toxic effects on the cardio-vascular system. An useful classification, published by the European Uremic Toxin Work Group (EUTox) is: 1) small water-soluble compounds; 2) protein-bound compounds; 3) the larger "middle molecules". High-flux membranes and more efficient treatment techniques, like HDF, improve the removal of uremic toxins in the middle molecular-weight range, and recent studies suggest that these strategies have better results on the morbidity and mortality...
September 28, 2017: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/28923026/dementia-and-cognitive-disorder-identified-at-a-forensic-psychiatric-examination-a-study-from-sweden
#7
Anette Ekström, Marianne Kristiansson, Karin Sparring Björkstén
BACKGROUND: Few studies have addressed the relationship between dementia and crime. We conducted a study of persons who got a primary or secondary diagnosis of dementia or cognitive disorder in a forensic psychiatric examination. METHODS: In Sweden, annually about 500 forensic psychiatric examinations are carried out. All cases from 2008 to 2010 with the diagnoses dementia or cognitive disorder were selected from the database of the Swedish National Board of Forensic Medicine...
September 18, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28919930/effects-of-12-weeks-of-nordic-walking-and-xco-walking-training-on-the-endurance-capacity-of-older-adults
#8
Tobias Morat, Jenny Krueger, Angus Gaedtke, Manuela Preuss, Joachim Latsch, Hans-Georg Predel
BACKGROUND: Several studies have already examined the positive effects of various forms of endurance training in patient groups and in healthy adults up to 60 years old. The aim of this study was to analyse the effects of Nordic Walking (NW) and XCO Walking (XCO) training on endurance capacity in healthy older adults, aged 60 years and older. METHODS: Twenty-three older participants (mean age: 69.9 ± 5.4 years) were randomly assigned to either the NW group or the XCO group...
2017: European Review of Aging and Physical Activity
https://www.readbyqxmd.com/read/28894045/neopterin-as-a-marker-of-cellular-immunological-response
#9
Łukasz Michalak, Magdalena Bulska, Karolina Strząbała, Piotr Szcześniak
Neopterin is a pyrazino-pyrimidine compound that belongs to the pteridine group. It is known to be a biochemical marker associated with cell-mediated immunity. It is produced by human monocytes/macrophages and dendritic cells from guanosine triphosphate (GTP) upon stimulation with interferon gamma (IFNγ), which is released by activated limphocytes Th. Neopterin is a very important clinic parameter, though the physiological role has not been exactly definited thus far. The level of neopterin reflects the stage of activation of the cellular immune system, which is important in the pathogenesis and progression of various diseases...
August 24, 2017: Postȩpy Higieny i Medycyny Doświadczalnej
https://www.readbyqxmd.com/read/28893184/the-canadian-hiv-and-aging-cohort-study-determinants-of-increased-risk-of-cardio-vascular-diseases-in-hiv-infected-individuals-rationale-and-study-protocol
#10
Madeleine Durand, Carl Chartrand-Lefebvre, Jean-Guy Baril, Sylvie Trottier, Benoit Trottier, Marianne Harris, Sharon Walmsley, Brian Conway, Alexander Wong, Jean-Pierre Routy, Colin Kovacs, Paul A MacPherson, Kenneth Marc Monteith, Samer Mansour, George Thanassoulis, Michal Abrahamowicz, Zhitong Zhu, Christos Tsoukas, Petronela Ancuta, Nicole Bernard, Cécile L Tremblay
BACKGROUND: With potent antiretroviral drugs, HIV infection is becoming a chronic disease. Emergence of comorbidities, particularly cardiovascular disease (CVD) has become a leading concern for patients living with the infection. We hypothesized that the chronic and persistent inflammation and immune activation associated with HIV disease leads to accelerated aging, characterized by CVD. This will translate into higher incidence rates of CVD in HIV infected participants, when compared to HIV negative participants, after adjustment for traditional CVD risk factors...
September 11, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28882918/prevalence-and-clinical-characteristics-of-apparent-therapy-resistant-hypertension-in-patients-with-cardiovascular-disease-a-cross-sectional-cohort-study-in-secondary-care
#11
Esther de Beus, Nicolette G C van der Sande, Michiel L Bots, Wilko Spiering, Michiel Voskuil, Frank L J Visseren, Peter J Blankestijn
OBJECTIVES: Our aim was to investigate the prevalence of apparent therapy-resistant hypertension (aTRH) in patients with clinical manifest cardiovascular disease (CVD), and to study clinical characteristics related to aTRH in this population. SETTING: The SMART (Second Manifestations of ARTerial disease) study is a large, single-centre cohort study in secondary care. PARTICIPANTS: Office blood pressure (BP) at inclusion was used to evaluate BP control in 6191 hypertensive patients with clinical manifest (cardio)vascular disease...
September 6, 2017: BMJ Open
https://www.readbyqxmd.com/read/28875833/phytocompounds-as-potential-agents-to-treat-obesity-cardiovascular-ailments
#12
Balaji Meriga, Muni Swamy Ganjayi, Brahma Naidu Parim
Obesity is no longer considered as a cosmetic issue as it is a potential risk factor to develop hypertension, type-2 diabetes, cardio vascular diseases (CVDs), infertility, arthritis etc. Apart from genetic factors, changes in life styles, food and work habits have lead to alarming raise in obesity ailments in both developed and developing countries. The excess and unutilized food takenin is converted into lipid components, primarily triglycerides and is stored in the liver, adipose and other tissues; if the positive energy balance extends a longer period it will lead to overweight, obesity and CVDs...
August 30, 2017: Cardiovascular & Hematological Agents in Medicinal Chemistry
https://www.readbyqxmd.com/read/28867036/-biological-monitoring-and-other-explorations-in-the-acute-phase-of-a-neonatal-arterial-ischemic-stroke-excluding-hemostasis
#13
G Favrais, S Nguyen The Tich
Neonatal monitoring and other explorations required just after neonatal arterial ischemic stroke (NAIS) diagnosis remain elusive. This review attempts to propose guidelines on this topic. During neonatal period, three major contexts related to NAIS emerge: 1) Metabolic disorders including hypoglycemia; 2) Early post-natal infections; 3) Cardio-vascular anomalies. Different patient profiles have been defined (typical, atypical and at risk profiles). According to these profiles, a final decisional tree including biological monitoring and complementary explorations has been suggested to caregivers...
September 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28856537/the-treatment-effect-of-an-ace-inhibitor-based-regimen-with-perindopril-in-relation-to-beta-blocker-use-in-29-463-patients-with-vascular-disease-a-combined-analysis-of-individual-data-of-advance-europa-and-progress-trials
#14
J J Brugts, M Bertrand, W Remme, R Ferrari, K Fox, S MacMahon, J Chalmers, M L Simoons, E Boersma
INTRODUCTION: In everyday practice, angiotensin converting enzyme inhibitors and beta-blockers are cornerstone treatments in patients with (cardio-)vascular disease. Clear data that evaluate the effects of the combination of these agents on morbidity and mortality are lacking. METHODS: In this retrospective pooled analysis of three large perindopril outcome trials (ADVANCE, EUROPA, PROGRESS), clinical outcomes were evaluated in 29,463 patients with vascular disease...
August 31, 2017: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/28837121/diagnostic-approach-to-pulmonary-hypertension-in-premature-neonates
#15
REVIEW
Vasantha H S Kumar
Bronchopulmonary dysplasia (BPD) is a form of chronic lung disease in premature infants following respiratory distress at birth. With increasing survival of extremely low birth weight infants, alveolar simplification is the defining lung characteristic of infants with BPD, and along with pulmonary hypertension, increasingly contributes to both respiratory morbidity and mortality in these infants. Growth restricted infants, infants born to mothers with oligohydramnios or following prolonged preterm rupture of membranes are at particular risk for early onset pulmonary hypertension...
August 24, 2017: Children
https://www.readbyqxmd.com/read/28804248/effect-of-chronic-hepatitis-c-virus-treatment-by-combination-therapy-on-cardiovascular-system
#16
Reda Biomy, Mohamed Abdelshafy, Ahmed Abdelmonem, Hesham Abu-Elenin, George Ghaly
BACKGROUND: The prevalence of hepatitis C virus (HCV) in Egypt is quite high, and the combined oral direct-acting antiviral agents (DAAs) may have impressive results. OBJECTIVE: To assess the cardiovascular effects of DAAs in patients with HCV. METHODS: A total of 170 patients with HCV were divided into 2 groups: first group (100 patients) received triple combination therapy (pegylated interferon alfa, sofosbuvir, and ribavirin, whereas the second group (70 patients) received dual combination therapy (sofosbuvir and simeprevir)...
2017: Clinical Medicine Insights. Cardiology
https://www.readbyqxmd.com/read/28793930/emerging-trends-and-patterns-of-self-reported-morbidity-in-india-evidence-from-three-rounds-of-national-sample-survey
#17
Kalosona Paul, Jayakant Singh
BACKGROUND: India is rapidly undergoing an epidemiological transition with a sudden change in the disease profile of its population. It is important to understand the changing nature of the burden of disease across the states of India for adequate policy intervention. METHODS: We analyzed the trend and pattern of self-reported morbidity across states of India using three rounds of (52nd, 60th and 71st) National Sample Survey Organization (NSSO) data. Descriptive analysis was carried out to understand the prevalence of self-reported morbidity variation over a period of two decades (1995-2014) and multivariate analysis was performed to identify the significant determinants of various types of self-reported morbidities...
August 9, 2017: Journal of Health, Population, and Nutrition
https://www.readbyqxmd.com/read/28769070/il6r-haplotype-rs4845625-t-rs4537545-c-is-a-risk-factor-for-simultaneously-high-crp-ldl-and-apob-levels
#18
A A Arguinano, E Naderi, N C Ndiaye, M Stathopoulou, S Dadé, B Alizadeh, S Visvikis-Siest
Interleukin 6 receptor (IL-6R), mediating IL-6's biological functions, plays an important role in different diseases such as diabetes, obesity and cardio-vascular diseases. In this study, we investigated the effects of two single nucleotide polymorphisms (SNPs), within the IL-6R loci, previously associated with C-reactive protein (CRP) and coronary heart diseases risk, and with controversial effects on lipids traits: SNP rs4845625 and SNP rs4537545. The results showed that both investigated SNPs were antagonistically related with CRP levels; the minor rs4845625*T allele was associated with increased CRP levels (P-value=0...
September 2017: Genes and Immunity
https://www.readbyqxmd.com/read/28763180/-improving-operating-room-efficiency-an-observational-and-multidimensional-approach-in-the-san-camillo-forlanini-hospital-rome
#19
Lucia Mitello, Fabrizio D'Alba, Francesca Milito, Cinzia Monaco, Daniela Orazi, Daniela Battilana, Anna Rita Marucci, Angelo Longo, Roberto Latina
AIM: The management of operating rooms (ORs) is a complex process which requires an effective organizational scheme. In order to amore convinient allocation of resources a rigorous monitoring plan is needed to ensure operating rooms performances. All the necessary actions should be taken to improve the quality of the planning and scheduling procedure. METHODS: Between April-December, 2016 an organizational analysis has been carried out on the performances of the A...
April 2017: Professioni Infermieristiche
https://www.readbyqxmd.com/read/28727855/association-of-apoe-gene-polymorphism-with-lipid-profile-and-coronary-artery-disease-in-afro-caribbeans
#20
Laurent Larifla, Christophe Armand, Jacqueline Bangou, Anne Blanchet-Deverly, Patrick Numeric, Christiane Fonteau, Carl-Thony Michel, Séverine Ferdinand, Véronique Bourrhis, Fritz-Line Vélayoudom-Céphise
OBJECTIVES: Apolipoprotein E gene (APOE) polymorphism is associated with the lipid profile and cardio-vascular disease. However, these relationships vary between ethnic groups. We evaluated, for the first time in an Afro-Caribbean population, the distribution of APOE polymorphisms and their associations with coronary artery disease (CAD), the lipid profile and other cardio-metabolic risk factors. METHODS: We studied 712 Afro-Caribbean subjects including 220 with documented CAD and 492 healthy subjects...
2017: PloS One
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