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https://www.readbyqxmd.com/read/28737483/tissue-lesions-due-to-spirorchiid-eggs-in-a-loggerhead-turtle-caretta-caretta-linnaeus-1758-from-brazil-the-first-report-outside-of-the-usa
#1
Rachel Bittencourt Ribeiro, Hassan Jerdy, Raphael Mansur Medina, Mariah Bianchi, Max Werneck, Eulógio Carvalho
Spirorchiids (family Spirorchiidae Stunkard 1921) are a group of flukes that inhabit the circulatory system of turtles. Infection by members of the family Spirorchiidae involves egg deposition in the host blood stream, accumulation in tissues, which cause inflammatory reactions and embolisms, leading or contributing to the death of the host. Reports of Spirorchiids eggs lesions on loggerhead turtle (Caretta caretta Linnaeus, 1758) were observed only in the USA hosts. In the present report a female loggerhead sea turtle was found dead on the beach in north State of Rio de Janeiro, Brazil...
July 24, 2017: Journal of Parasitology
https://www.readbyqxmd.com/read/28736933/disruption-of-oxidative-balance-in-the-gut-of-the%C3%A2-western-honeybee-apis-mellifera-exposed-to-the-intracellular-parasite-nosema-ceranae-and-to-the-insecticide-fipronil
#2
Laurianne Paris, Michaël Roussel, Bruno Pereira, Frédéric Delbac, Marie Diogon
The causes underlying the increased mortality of honeybee colonies remain unclear and may involve multiple stressors acting together, including both pathogens and pesticides. Previous studies suggested that infection by the gut parasite Nosema ceranae combined with chronic exposure to sublethal doses of the insecticide fipronil generated an increase in oxidative stress in the midgut of honeybees. To explore the impact of these two stressors on oxidative balance, we experimentally infected bees with N. ceranae and/or chronically exposed to fipronil at low doses for 22 days, and we measured soluble reactive oxygen species (ROS) and ROS damage by quantifying both protein and lipid oxidation in the midgut...
July 24, 2017: Microbial Biotechnology
https://www.readbyqxmd.com/read/28732017/disease-severity-in-patients-with-visceral-leishmaniasis-is-not-altered-by-co-infection-with-intestinal-parasites
#3
Fitsumbrhan Tajebe, Mulusew Getahun, Emebet Adem, Asrat Hailu, Mulualem Lemma, Helina Fikre, John Raynes, Aschalew Tamiru, Zemenay Mulugeta, Ermias Diro, Frederic Toulza, Ziv Shkedy, Tadesse Ayele, Manuel Modolell, Markus Munder, Ingrid Müller, Yegnasew Takele, Pascale Kropf
Visceral leishmaniasis (VL) is a neglected tropical disease that affects the poorest communities and can cause substantial morbidity and mortality. Visceral leishmaniasis is characterized by the presence of Leishmania parasites in the spleen, liver and bone marrow, hepatosplenomegaly, pancytopenia, prolonged fever, systemic inflammation and low body mass index (BMI). The factors impacting on the severity of VL are poorly characterized. Here we performed a cross-sectional study to assess whether co-infection of VL patients with intestinal parasites influences disease severity, assessed with clinical and haematological data, inflammation, cytokine profiles and BMI...
July 21, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28730516/cryptosporidium-infection-in-children-with-cancer-undergoing-chemotherapy-how-important-is-the-prevention-of-opportunistic-parasitic-infections-in-patients-with-malignancies
#4
Reza Berahmat, Mahmoud Mahami-Oskouei, Azim Rezamand, Adel Spotin, Nayyereh Aminisani, Roghayeh Ghoyounchi, Solmaz Madadi
Cryptosporidiosis is a relatively uncommon disease in healthy individuals but could be potentially worrisome in immunocompromised patients. This study aimed to evaluate Cryptosporidium infection in children with cancer undergoing chemotherapy. A case-control study was conducted in 132 children with cancer undergoing chemotherapy and 132 non-cancer controls. The modified Ziehl-Neelsen (MZN) staining and polymerase chain reaction methods were used for the detection of Cryptosporidium parasite. All positive isolates were sequenced for phylogenetic analysis...
July 20, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28727765/defining-the-target-and-the-effect-of-imatinib-on-the-filarial-c-abl-homologue
#5
Elise M O'Connell, Olena Kamenyeva, Sara Lustigman, Aaron Bell, Thomas B Nutman
BACKGROUND: Previously we demonstrated the micro- and macrofilaricidal properties of imatinib in vitro. Here we use electron and multiphoton microscopy to define the target of imatinib in the adult and microfilarial stages of Brugia malayi, and assess the effects of pharmacologically relevant levels of imatinib on the adult parasites. METHODS: After fixation of adult B. malayi males and females, sections were stained with polyclonal rabbit anti-c-Abl antibody (or isotype control) and imaged with multiphoton fluorescent microscopy...
July 20, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28725553/behavioral-physiological-and-morphological-correlates-of-parasite-intensity-in-the-wild-cururu-toad-rhinella-icterica
#6
Eduardo Hermógenes Moretti, Braz Titon, Carla Bonetti Madelaire, Raquel de Arruda, Tatiana Alvarez, Fernando Ribeiro Gomes
Large numbers of parasites are found in various organs of anuran amphibians, with parasite intensities thought to modulate the host's Darwinian fitness traits. Interaction between the anuran hosts and their multiple parasites should modulate the host's phenotypic characteristic, such as those associated with high energetic demand (such as calling effort and locomotor performance), energy balance (standard metabolic rate), and morphological plasticity (as indicated by organ masses). The present study investigated the impact of parasite intensities on the behavioral, physiological, and morphological traits of wild adult male Rhinella icterica (Anura: Bufonidae)...
December 2017: International Journal for Parasitology. Parasites and Wildlife
https://www.readbyqxmd.com/read/28722585/school-children-s-intestinal-parasite-and-nutritional-status-1-year-after-complementary-school-garden-nutrition-water-sanitation-and-hygiene-interventions-in-burkina-faso
#7
Séverine Erismann, Serge Diagbouga, Christian Schindler, Peter Odermatt, Astrid M Knoblauch, Jana Gerold, Andrea Leuenberger, Akina Shrestha, Grissoum Tarnagda, Jürg Utzinger, Guéladio Cissé
The potential health benefits of combined agricultural, nutrition, water, sanitation, and hygiene (WASH) interventions are poorly understood. We aimed to determine whether complementary school garden, nutrition, and WASH interventions reduce intestinal parasites and improve school children's nutritional status in two regions of Burkina Faso. A cluster-randomized controlled trial was conducted in the Plateau Central and Center-Ouest regions of Burkina Faso. A total of 360 randomly selected children, aged 8-15 years, had complete baseline and end-line survey data...
July 10, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28722574/intestinal-parasitic-infections-in-human-immunodeficiency-virus-infected-and-noninfected-persons-in-a-high-human-immunodeficiency-virus-prevalence-region-of-cameroon
#8
Céline Nguefeu Nkenfou, Sandrine Mboula Tchameni, Carine Nguefeu Nkenfou, Patrice Djataou, Ulrich Florian Simo, Alexandre Benjamin Nkoum, William Estrin
The problem of intestinal parasitic infection in human immunodeficiency virus (HIV)-infected people requires careful consideration in the developing world where poor nutrition is associated with poor hygiene and several coinfecting diseases. Studies have addressed this issue in Cameroon, especially in the low HIV prevalence area. The current study was conducted to determine the prevalence of intestinal parasitosis in people living with HIV (PLHIV) in Adamaoua and to identify associated risk factors. Stool and blood specimens from study participants were screened for intestinal parasites and anti-HIV antibodies, respectively...
June 26, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28722573/killing-of-cryptosporidium-sporozoites-by-lactoferrin
#9
Jose Luis Paredes, Hayley Sparks, A Clinton White, Griselle Martinez-Traverso, Theresa Ochoa, Alejandro Castellanos-González
Intestinal infection caused by Cryptosporidium is a major contributor to diarrhea morbidity and mortality in young children around the world. Current treatments for children suffering from cryptosporidiosis are suboptimal. Lactoferrin is a glycoprotein found in breast milk. It has showed bacteriostatic and antimicrobial activity in the intestine. However, the effects of lactoferrin on the intestinal parasite Cryptosporidium have not been reported. In this study, we investigated the anticryptosporidial activity of human lactoferrin on different stages of Cryptosporidium...
July 3, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28722571/more-poop-more-precision-improving-epidemiologic-surveillance-of-soil-transmitted-helminths-with-multiple-fecal-sampling-using-the-kato-katz-technique
#10
Chengfang Liu, Louise Lu, Linxiu Zhang, Yu Bai, Alexis Medina, Scott Rozelle, Darvin Scott Smith, Changhai Zhou, Wei Zang
Soil-transmitted helminths, or parasitic intestinal worms, are among the most prevalent and geographically widespread parasitic infections in the world. Accurate diagnosis and quantification of helminth infection are critical for informing and assessing deworming interventions. The Kato-Katz thick smear technique, the most widely used laboratory method to quantitatively assess infection prevalence and infection intensity of helminths, has often been compared with other methods. Only a few small-scale studies, however, have considered ways to improve its diagnostic sensitivity...
July 3, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28719956/a-case-of-ectopic-peritoneal-paragonimiasis-mimicking-diverticulitis-or-abdominal-abscess
#11
Min Jae Kim, Sung-Han Kim, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Jun Hee Woo, Yong Sik Yoon, Kyung Won Kim, Jaeeun Cho, Jong-Yil Chai, Yong Pil Chong
Paragonimiasis is a parasitic disease caused by Paragnonimus species. The primary site of infection is the lung, and extrapulmonary involvement is also reported. When infected with Paragonimus westermani, which is the dominant species in Korea, the central nervous system is frequently involved along with the liver, intestine, peritoneal cavity, retroperitoneum, and abdominal wall. Ectopic paragonimiasis raises diagnostic challenge since it is uncommon and may be confused with malignancy or other inflammatory diseases...
June 2017: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/28719290/performance-of-real-time-polymerase-chain-reaction-assays-for-the-detection-of-20-gastrointestinal-parasites-in-clinical-samples-from-senegal
#12
Doudou Sow, Philippe Parola, Khadime Sylla, Magatte Ndiaye, Pascal Delaunay, Philippe Halfon, Sabine Camiade, Thérèse Dieng, Roger C K Tine, Babacar Faye, Jean Louis Ndiaye, Yémou Dieng, Oumar Gaye, Didier Raoult, Fadi Bittar
Gastrointestinal parasite infections represent one of the biggest public health problems in the world. Therefore, appropriate innovative tools are needed for assessing interventions to control these infections. This study aims to compare the performance of real-time polymerase chain reaction (PCR) assays to microscopic examination for detection of intestinal parasites. A direct microscopic examination and stool concentration was performed on 98 stool samples from patients attending Senegalese hospitals. Negative microscopic control samples were also collected in Nice and Marseille (France)...
July 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28719267/comparison-of-cytokine-responses-in-ecuadorian-children-infected-with-giardia-ascaris-or-both-parasites
#13
Jill Weatherhead, Andrea Arévalo Cortés, Carlos Sandoval, Maritza Vaca, Martha Chico, Sophia Loor, Philip J Cooper, Rojelio Mejia
AbstractMore than 2 billion people are infected with parasites globally, and the majority have coinfections. Intestinal protozoa and helminths induce polarizing CD4(+) T-helper cell 1 (Th1) mediated cytokine responses within the host. Such immune polarization may inhibit the ability of the host to mount an adequate immune response for pathogen clearance to concurrent pathogens. The current study evaluated the plasma cytokine profile in Ascaris and Giardia coinfected children compared with Giardia- and Ascaris-only infected children...
June 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28717211/epithelial-cell-specific-raptor-is-required-for-initiation-of-type-2-mucosal-immunity-in-small-intestine
#14
Bola Aladegbami, Lauren Barron, James Bao, Jason Colasanti, Christopher R Erwin, Brad W Warner, Jun Guo
Intestinal tuft cells are one of 4 secretory cell linages in the small intestine and the source of IL-25, a critical initiator of the type 2 immune response to parasite infection. When Raptor, a critical scaffold protein for mammalian target of rapamycin complex 1 (mTORC1), was acutely deleted in intestinal epithelium via Tamoxifen injection in Tritrichomonas muris (Tm) infected mice, tuft cells, IL-25 in epithelium and IL-13 in the mesenchyme were significantly reduced, but Tm burden was not affected. When Tm infected mice were treated with rapamycin, DCLK1 and IL-25 expression in enterocytes and IL-13 expression in mesenchyme were diminished...
July 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28715423/antibody-trapping-a-novel-mechanism-of-parasite-immune-evasion-by-the-trematode-echinostoma-caproni
#15
Alba Cortés, Javier Sotillo, Carla Muñoz-Antolí, Javier Molina-Durán, J Guillermo Esteban, Rafael Toledo
BACKGROUND: Helminth infections are among the most prevalent neglected tropical diseases, causing an enormous impact in global health and the socioeconomic growth of developing countries. In this context, the study of helminth biology, with emphasis on host-parasite interactions, appears as a promising approach for developing new tools to prevent and control these infections. METHODS/PRINCIPAL FINDINGS: The role that antibody responses have on helminth infections is still not well understood...
July 17, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28711437/intestinal-parasitic-infections-current-status-and-associated-risk-factors-among-school-aged-children-in-an-archetypal-african-urban-slum-in-nigeria
#16
Vincent P Gyang, Ting-Wu Chuang, Chien-Wei Liao, Yueh-Lun Lee, Olaoluwa P Akinwale, Akwaowo Orok, Olusola Ajibaye, Ajayi J Babasola, Po-Ching Cheng, Chia-Mei Chou, Ying-Chieh Huang, Pasaiko Sonko, Chia-Kwung Fan
BACKGROUND/PURPOSE: Intestinal parasitic infections (IPIs) among school aged children (SAC) in Nigeria remains endemic, hence the need for regular surveillance to attract the attention of policy makers. This cross-sectional study investigated the current prevalence and factors associated with intestinal parasitic infections among school aged children in an urban slum of Lagos City, Nigeria. METHODS: Single stool samples from 384 school aged children (188 boys and 196 girls) were examined by employing Merthiolate-iodine-formaldehyde concentration (MIFC) and Kato-Katz methods...
June 22, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28702802/morphological-ultrastructural-and-molecular-characterization-of-intestinal-tetratrichomonads-isolated-from-non-human-primates-in-southeastern-brazil
#17
Caroline Spitz Dos Santos, Vera Lúcia Teixeira de Jesus, Douglas McIntosh, Caroline Cunha Carreiro, Lilian Cristina Oliveira Batista, Bruno do Bomfim Lopes, Daniel Marchesi Neves, Carlos Wilson Gomes Lopes
Non-human primates are our closest relatives and represent an interesting model for comparative parasitological studies. However, research on this topic particularly in relation to intestinal parasites has been fragmentary and limited mainly to animals held in captivity. Thus, our knowledge of host-parasite relationships in this species-rich group of mammals could be considered rudimentary. The current study combined morphological, ultrastructural, and molecular analyses to characterize isolates of intestinal tetratrichomonads recovered from the feces of three species of South American, non-human primates...
July 13, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28702801/exposure-to-anisakis-extracts-can-induce-inflammation-on-in-vitro-cultured-human-colonic-cells
#18
Antonio Speciale, Domenico Trombetta, Antonella Saija, Antonio Panebianco, Filippo Giarratana, Graziella Ziino, Paola Lucia Minciullo, Francesco Cimino, Sebastiano Gangemi
Anisakis spp. is a parasitic nematode whose infective third-stage larvae may be found within the flesh of fish species commonly consumed by humans. Thorough cooking or freezing should render the fish safe for consumption; furthermore, marinating solutions containing biocidal agents might have a significant action against Anisakis larvae. Some studies suggest a relationship between some parasitic infections and development of inflammatory bowel disorders, and Anisakis infection might be a risk factor for stomach or colon cancer...
July 12, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28695829/does-the-intestinal-parasite-enterobius-vermicularis-cause-acute-appendicitis
#19
Yavuz Pirhan, Fatma Zeynep Özen, Çetin Kılınç, Rıdvan Güçkan
OBJECTIVE: Although intestinal parasitic infections rarely cause acute appendicitis, they are common public health problems in undeveloped and developing countries. Parasitic infections should be kept in mind in patients clinically suspected of having acute appendicitis, and treatment procedures should be adopted according to the etiology. METHODS: Herein we presented the cases of four patients with clinical findings of acute appendicitis. Patients were clinically suspected of having acute appendicitis, and Enterobius vermicularis was detected in the pathological examinations of specimens...
June 2017: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/28693649/morphological-and-molecular-characterization-of-tarantobelus-arachnicida-gen-n-sp-n-nematoda-rhabditida-brevibuccidae-a-parasitic-nematode-of-tarantulas
#20
J Abolafia, R Peña-Santiago
A new genus and new species, Tarantobelus arachnicida, was found in the oral opening of tarantula spiders bred in captivity in Poland. The new species is characterized by having a small body (0.77-0.95 mm long in females and 0.66-0.84 mm in males), cuticle poorly annulated by transverse incisures, lateral field inconspicuous, lips separated with small cuticular flaps topping each lip, stoma panagrolaimoid with gymnostom well developed with robust and refringent rhabdia, pharynx panagrolaimoid with isthmus slightly longer than the basal bulb, intestine with cardiac (anterior) and rectal (posterior) areas with narrower walls...
July 11, 2017: Journal of Helminthology
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