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Maria Papageorgiou, Daniel Martin, Hannah Colgan, Simon Cooper, Julie P Greeves, Jonathan C Y Tang, William D Fraser, Kirsty J Elliott-Sale, Craig Sale
PURPOSE: We aimed to explore the effects of low energy availability (EA)[15 kcal·kg lean body mass (LBM)-1 ·d-1 ] achieved by diet or exercise on bone turnover markers in active, eumenorrheic women. METHODS: By using a crossover design, ten eumenorrheic women (VO2 peak : 48.1 ± 3.3 ml·kg-1 ·min-1 ) completed all three, 3-day conditions in a randomised order: controlled EA (CON; 45 kcal·kgLBM-1 ·d-1 ), low EA through dietary energy restriction (D-RES; 15 kcal·kgLBM-1 ·d-1 ) and low EA through increasing exercise energy expenditure (E-RES; 15 kcal·kgLBM-1 ·d-1 ), during the follicular phase of three menstrual cycles...
June 19, 2018: Bone
Elham Rahmani, Samad Akbarzadeh, Ainaz Broomand, Fatemeh Torabi, Niloofar Motamed, Marzieh Zohrabi
BACKGROUND: Polycystic ovary syndrome (PCOS) is a common endocrine disease in women of reproduction age and a major cause of anovulatory infertility. Insulin resistance plays an important role in the development and durability of this disorder. ANGPTL2 is known as an inflammatory mediator derived from adipose tissue that links obesity to systemic insulin resistance, and obestatin has been identified as a hormone associated with insulin resistance that suppresses food reabsorption, inhibits gastric emptying and decreases weight gain...
June 22, 2018: Journal of Clinical Medicine
Sze Chuen Cesar Wong, Thomas Chi Chuen Au, Sammy Chung Sum Chan, Lawrence Po Wah Ng, Hin Fung Tsang
Background: Human papillomavirus (HPV) is a known causative factor in the etiology of cervical cancer. Methods: HPV DNA genotyping was performed in menstrual blood (MB) collected in napkins from patients with cervical intraepithelial neoplasia (CIN), HPV infection and sexually active apparently normal subjects. In the same patient cohort, MB TAP1 I333V and TAP1 D637G gene polymorphisms were examined. Results: The sensitivity, specificity, positive and negative predictive values of HPV DNA to detect CIN or HPV infection was 83% (223/268), 98% (131/134), 99% (223/226) and (74%) 131/176, respectively...
June 19, 2018: Journal of Infectious Diseases
Moona M Myllyaho, Johanna K Ihalainen, Anthony C Hackney, Maarit Valtonen, Ari Nummela, Elina Vaara, Keijo Häkkinen, Heikki Kyröläinen, Ritva S Taipale
Myllyaho, MM, Ihalainen, JK, Hackney, AC, Valtonen, M, Nummela, A, Vaara, E, Häkkinen, K, Kyröläinen, H, and Taipale, RS. Hormonal contraceptive use does not affect strength, endurance, or body composition adaptations to combined strength and endurance training in women. J Strength Cond Res XX(X): 000-000, 2018-This study examined the effects of a 10-week period of high-intensity combined strength and endurance training on strength, endurance, body composition, and serum hormone concentrations in physically active women using hormonal contraceptives (HCs, n = 9) compared with those who had never used hormonal contraceptives (NHCs, n = 9)...
June 20, 2018: Journal of Strength and Conditioning Research
N B Paramonova, E A Kogan, A V Kolotovkina, O V Burmenskaya
OBJECTIVE: To study endometrial receptivity in infertile women with external genital endometriosis (EGE). SUBJECTS AND METHODS: Clinical, morphological, immunohistochemical, and molecular genetic examinations of endometrial aspiration pipelle biopsy specimens obtained on days 22-24 of the menstrual cycle from 94 infertile women with endometriosis: 50 women with Stage I-II EGE and 44 women with ovarian endometrioid cysts (OEC). A control group consisted of 54 women with tubal peritoneal factor of infertility (TPFI) and a successful attempt at IVF...
2018: Arkhiv Patologii
Corrie J Alonzo, Vijay P Nagraj, Jenna V Zschaebitz, Douglas E Lake, J Randall Moorman, Michael C Spaeder
OBJECTIVE: There are limited evidence-based published heart rate ranges for premature neonates. We determined heart rate ranges in premature neonates based on gestational and post-menstrual age. STUDY DESIGN: Retrospective observational study of premature neonates admitted to the neonatal intensive care unit at the University of Virginia between January 2009 and October 2015. We included gestational ages between 23 0/7 weeks and 34 6/7 weeks. We stratified data by gestational and post-menstrual age groups...
June 21, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
Rabindra Nath Sinha, Bobby Paul
No abstract text is available yet for this article.
April 2018: Indian Journal of Public Health
Iwona Szydłowska, Aleksandra Marciniak, Agnieszka Brodowska, Marcin Lisak, Sylwia Przysiecka, Jacek Różański
The aim of the study was to evaluate whether ovarian reserve depends on chronic kidney disease. Twenty-four patients, 23-45 years with chronic kidney disease (CKD) stages 3-4 were included in the study. All the patients underwent transvaginal ultrasounds to assess antral follicle count (AFC) and ovarian volume. The serum samples were obtained on days 3-5 of the menstrual cycle from all participants for anti-Mullerian hormone (AMH), follicle stimulating hormone (FSH), and estradiol (E2) levels. On the base of the study, it was concluded that the most sensitive parameters of ovarian reserve are AMH and AFC...
June 19, 2018: Gynecological Endocrinology
Brenna E Swift, Eric Leung, Danielle Vicus, Allan Covens
This study evaluates a novel technique of laparoscopic ovarian transposition performed by Gynecologic Oncologists prior to pelvic radiation for gynecologic cancer. A retrospective review was completed of all patients that underwent laparoscopic ovarian transposition from February 2007 to June 2017 at one tertiary care cancer. The technique involves salpingectomy, followed by retroperitoneal dissection to move the ovaries lateral to the hepatic and splenic flexures of the colon. Normal ovarian function was defined by the absence of vasomotor symptoms, FSH and menstrual history (if menstruating)...
May 2018: Gynecologic Oncology Reports
Chan-Hee Jung, Ji-Oh Mok, Sung Woon Chang, Bora Lee, Ji Hyon Jang, Sukho Kang, Sang Hee Jung
It is suggested that vitamin D level and age at menarche are related to each other, and the prevalence of low vitamin D status and early menarche in women is increasing worldwide. Moreover, several studies revealed that both of them are associated with metabolic syndrome (MetS). Therefore, we hypothesized that there are significant associations among vitamin D status, age at menarche, and MetS and that the relationships differ according to menstrual state. We assessed whether the association among MetS, vitamin D, and menarche age is different between premenopausal and postmenopausal women and whether there is a change in risk of MetS according to vitamin D level in different age-at-menarche groups...
July 2018: Nutrition Research
Zehra Sema Özkan, Derya Deveci, Nusret Akpolat, Fulya İlhan, Mehmet Şimşek, Hüseyin Timurkan
Background/aim: To investigate the possible differences in endometrial leukocyte subtype distribution between women with unexplained infertility and normal fertile women and to determine whether there is a correlation between endometrial leukocyte counts and plasma cytokine levels in unexplained infertility. Materials and methods: This case-control study involved 79 infertile and 40 fertile women. Peripheral venous blood samples and endometrial samples were obtained on day 21 of the menstrual cycle. Plasma interleukin-4 (IL4), IL6, IL10, IL17, IL35, interferongamma (IFN-g), tumor necrosis factor-alpha (TNF-a), transforming growth factor-beta (TGF-b), and suppressor of cytokine signaling-3 (SOCS3) levels were determined by enzyme-linked immunosorbent assay...
June 14, 2018: Turkish Journal of Medical Sciences
Maria Gullander, Stein Knardahl, Dagfinn Matre
Aabstract Background and purpose Women exhibit higher prevalence of most painful disorders. Several explanations have been proposed for this discrepancy, one being that endogenous pain modulatory pathways, which affect incoming nociceptive signals, act differently in men and women. A less efficient pain inhibitory system has been proposed as a contributing factor to explain why women exhibit higher prevalence of most painful disorders. The present study determined whether muscle pain, induced experimentally by electrical stimulation, is inhibited by a painful heat stimulus...
December 29, 2017: Scandinavian Journal of Pain
Christine Mohn, Olav Vassend, Stein Knardahl
Background and purpose The psychophysiological responses to and modulation of pressure pain stimulation are relatively new areas of investigation. The aims of the present study were to characterize subjective and cardiovascular (CV) responses to pressure pain stimulation, and to examine the relationship between CV responding and pain pressure pain sensitivity. Methods Thirty-nine pain-free, normotensive women were included in the study and tested during the follicular phase of their menstrual cycles. Pain threshold and tolerance were recorded at the right masseter muscle and the sternum, and visual analogue scales (VAS) were used to rate both pain intensity (the sensory dimension) and discomfort (the affective dimension)...
December 29, 2017: Scandinavian Journal of Pain
Deanna L Kelly, Megan M Powell, Heidi J Wehring, MacKenzie A Sayer, Ann Marie Kearns, Ann L Hackman, Robert W Buchanan, Rebecca B Nichols, Heather A Adams, Charles M Richardson, Gopal Vyas, Robert P McMahon, Amber K Earl, Kelli M Sullivan, Fang Liu, Sarah E Luttrell, Faith B Dickerson, Stephanie M Feldman, Supriya Narang, Maju M Koola, Peter F Buckley, Jill A RachBeisel, Joseph P McEvoy
PURPOSE/BACKGROUND: Prolactin-related adverse effects contribute to nonadherence and adverse health consequences, particularly in women with severe mental illness. Treating these adverse effects may improve treatment acceptability, adherence, and long-term outcomes. METHODS/PROCEDURES: Premenopausal women with a Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision diagnosis of schizophrenia, schizoaffective disorder, or bipolar disorder were recruited for a randomized, double-blind, placebo-controlled 16-week trial of adjunct aripiprazole (5-15 mg/d)...
June 15, 2018: Journal of Clinical Psychopharmacology
Laura Freitas, Tânia Amorim, Ludovic Humbert, Roger Fonollá, Andreas D Flouris, George S Metsios, Athanasios Z Jamurtas, Yiannis Koutedakis
Given the lack of relevant data, the aim of this study was to examine femur cortical and trabecular bone in female and male professional ballet dancers. 40 professional ballet dancers and 40 sex- and age-matched non-exercising controls volunteered. Femoral bone density was scanned by dual-energy X-ray absorptiometry (DXA) scan. A 3D-DXA software was used to analyse trabecular and cortical bone. Anthropometry, maturation (Tanner staging), menstrual parameters (age at menarche and primary amenorrhea), energy availability and nutritional analysis (3-day record) were also assessed...
June 18, 2018: Journal of Sports Sciences
Viviana Mucci, Josephine M Canceri, Rachael Brown, Mingjia Dai, Sergei B Yakushin, Shaun Watson, Angelique Van Ombergen, Yves Jacquemyn, Paul Fahey, Paul H Van de Heyning, Floris Wuyts, Cherylea J Browne
Introduction: Mal de Debarquement Syndrome (MdDS) is a condition characterized by a persistent perception of self-motion, in most cases triggered from exposure to passive motion (e.g., boat travel, a car ride, flights). Patients whose onset was triggered in this way are categorized as Motion-Triggered (MT) subtype or onset group. However, the same syndrome can occur spontaneously or after non-motion events, such as childbirth, high stress, surgery, etc. Patients who were triggered in this way are categorized as being of the Spontaneous/Other (SO) subtype or onset group...
2018: Frontiers in Neurology
Madhuri S Kurdi, Ashwini H Ramaswamy
The menstrual cycle is a physiological phenomenon that is accompanied by several hormonal fluctuations involving oestrogen and progesterone. Oestrogen and progesterone exert several physiological effects. There are many questions pertaining to the influence of the physiology of menstruation on anaesthesia. We attempted to find out whether the phase of the menstrual cycle can alter the physiological functions during anaesthesia, the perioperative management and outcomes. We performed a literature search in Google Scholar, PubMed and Cochrane databases for original and reviewed articles on the phases of the menstrual cycle and their relation to anaesthesia-related physiological parameters to find an answer to these questions...
May 2018: Indian Journal of Anaesthesia
Sabina Zacharieva, Ralitsa Robeva, Silvia Andonova, Radoslava Vazharova, Lubomir Balabanski, Maya Atanasoska, Draga Toncheva, Atanaska Elenkova, Alexey Savov
11β-Hydroxylase deficiency is the second most common enzyme disorder after 21-hydroxylase deficiency causing congenital adrenal hyperplasia (CAH11β ). In females, the clinical phenotype of CAH11β classic forms is associated with ambiguous genitalia, virilization and hypertension, while most common complaints in milder non-classic forms include hirsutism, acne, menstrual disturbances, and infertility. Herein, we present clinical and genetic characteristics of an adult woman with 11β-hydroxylase deficiency, hypertension and infertility; she has been followed up from her first pregnancy to her early menopause...
June 17, 2018: Gynecological Endocrinology
Taeryoon Kim, Ga Eun Nam, Byoungduck Han, Sung Jung Cho, Junghun Kim, Do Hyun Eum, Sang Woo Lee, Soon Hong Min, Woohyun Lee, Kyungdo Han, Yong Gyu Park
This study aimed to examine whether the characteristics of mental health and sleep duration, alone or in combination, are associated with menstrual cycle irregularity. This population-based, cross-sectional study analyzed the data from 4445 women aged 19-49 years, who participated in the Korea National Health and Nutrition Examination Survey 2010-2012. A structured questionnaire was used to assess mental health characteristics, sleep duration, and menstrual cycle irregularity. A multivariable logistic regression analysis was performed...
June 16, 2018: Archives of Women's Mental Health
Hacer Sahin Aydınyurt, Yusuf Ziya Yuncu, Yasin Tekin, Abdullah Seckin Ertugrul
OBJECTIVES: Sex steroid hormones are thought to affect periodontal tissues. A clear understanding of the effect of the menstrual cycle on oral tissues would be an important milestone in the timing of dental interventions in the future. The aim of this longitudinal, prospective study was to evaluate clinical periodontal parameters and levels of interleukin-6 (IL-6) and tumour necrosis factor alpha (TNF-α) in gingival crevicular fluid (GCF) during the menstrual cycle. METHODS: Forty-five patients were included in this study...
June 16, 2018: Oral Diseases
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