keyword
MENU ▼
Read by QxMD icon Read
search

nBI

keyword
https://www.readbyqxmd.com/read/28732392/systematic-assessment-with-i-scan-magnification-endoscopy-and-acetic-acid-improves-dysplasia-detection-in-patients-with-barrett-s-esophagus
#1
Gideon Lipman, Raf Bisschops, Vinay Sehgal, Jacobo Ortiz-Fernández-Sordo, Rami Sweis, Jose M Esteban, Rifat Hamoudi, Matthew R Banks, Krish Ragunath, Laurence B Lovat, Rehan J Haidry
Background and study aims Enhanced endoscopic imaging with chromoendoscopy may improve dysplasia recognition in patients undergoing assessment of Barrett's esophagus (BE). This may reduce the need for random biopsies to detect more dysplasia. The aim of this study was to assess the effect of magnification endoscopy with I-SCAN (Pentax, Tokyo, Japan) and acetic acid (ACA) on dysplasia detection in BE using a novel mucosal and vascular classification system. Methods BE segments and suspicious lesions were recorded with high definition white-light and magnification endoscopy enhanced using all I-SCAN modes in combination...
July 21, 2017: Endoscopy
https://www.readbyqxmd.com/read/28731617/in-vivo-diagnosis-of-early-stage-gastric-cancer-found-after-helicobacter-pylori-eradication-using-probe-based-confocal-laser-endomicroscopy
#2
Noriyuki Horiguchi, Tomomitsu Tahara, T Hyuga Yamada, Dai Yoshida, Masaaki Okubo, Mitsuo Nagasaka, Yoshihito Nakagawa, Tomoyuki Shibata, Tetsuya Tsukamoto, Makoto Kuroda, Naoki Ohmiya
BACKGROUND AND AIM: Early-stage gastric cancer (EGC) found after Helicobacter pylori (Hp) eradication often displays non-tumorous regenerative epithelium and/or maturated tumorous epithelium overlying the cancerous tissue, which may confuse endoscopic and histologic diagnosis. Probe-based confocal laser endomicroscopy (pCLE) enables in vivo real-time optical biopsy. We compared the diagnostic yields for these EGC cases using conventional white light endoscopy (WL), magnifying endoscopy with narrow-band imaging (ME-NBI), pCLE, and endoscopic biopsy; we also compared the accuracy of the horizontal extent diagnosis between ME-NBI and pCLE...
July 21, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28713060/a-standardized-imaging-protocol-for-the-endoscopic-prediction-of-dysplasia-within-sessile-serrated-polyps-with-video
#3
David J Tate, Mahesh Jayanna, Halim Awadie, Lobke Desomer, Ralph Lee, Stephen J Heitman, Mayenaaz Sidhu, Kathleen Goodrick, Nicholas G Burgess, Hema Mehajan, Duncan McLeod, Michael J Bourke
BACKGROUND AND AIMS: Dysplasia within sessile serrated polyps (SSPs) is difficult to detect, may be mistaken for an adenoma risking incomplete resection of the background serrated tissue, and is strongly implicated in interval cancer after colonoscopy. The use of endoscopic imaging to detect dysplasia within SSP has not been systematically studied. METHODS: Consecutively detected SSP ≥8 mm in size were evaluated using a standardized imaging protocol at a tertiary endoscopy center over 3 years...
July 13, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28706424/new-magnifying-endoscopic-classification-for-superficial-esophageal-squamous-cell-carcinoma
#4
Su Jin Kim, Gwang Ha Kim, Moon Won Lee, Hye Kyung Jeon, Dong Hoon Baek, Bong Eun Lee, Geun Am Song
AIM: To assess the accuracy of a new magnifying endoscopy (ME) classification for predicting depth of invasion of superficial esophageal squamous cell carcinoma (SESCC). METHODS: This study included a total of 70 lesions in 69 patients with SESCC who underwent ME with narrow-band imaging (ME-NBI) before resection from August 2010 to July 2016. Accuracy of ME-NBI for predicting depth of invasion of SESCC was analyzed by using a new ME classification proposed by the Japan Esophageal Society (JES), and interobserver agreement was assessed...
June 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28706415/role-of-new-endoscopic-techniques-in-inflammatory-bowel-disease-management-has-the-change-come
#5
EDITORIAL
Loredana Goran, Lucian Negreanu, Ana Maria Negreanu
Despite significant therapeutic progress in recent years, inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, remains a challenge regarding its pathogenesis and long-term complications. New concepts have emerged in the management of this disease, such as the "treat-to-target" concept, in which mucosal healing plays a key role in the evolution of IBD, the risk of recurrence and the need for surgery. Endoscopy is essential for the assessment of mucosal inflammation and plays a pivotal role in the analysis of mucosal healing in patients with IBD...
June 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28705636/a-review-of-bioinformatics-platforms-for-comparative-genomics-recent-developments-of-the-edgar-2-0-platform-and-its-utility-for-taxonomic-and-phylogenetic-studies
#6
J Yu, J Blom, S P Glaeser, S Jaenicke, T Juhre, O Rupp, O Schwengers, S Spänig, A Goesmann
The rapid development of next generation sequencing technology has greatly increased the amount of available microbial genomes. As a result of this development, there is a rising demand for fast and automated approaches in analyzing these genomes in a comparative way. Whole genome sequencing also bears a huge potential for obtaining a higher resolution in phylogenetic and taxonomic classification. During the last decade, several software tools and platforms have been developed in the field of comparative genomics...
July 10, 2017: Journal of Biotechnology
https://www.readbyqxmd.com/read/28702753/magnifying-nbi-patterns-of-gastric-mucosa-after-helicobacter-pylori-eradication-and-its-potential-link-to-the-gastric-cancer-risk
#7
Tomomitsu Tahara, Sayumi Tahara, Tetsuya Tuskamoto, Noriyuki Horiguchi, Dai Yoshida, Tomohiko Kawamura, Masaaki Okubo, Mitsuo Nagasaka, Yoshihito Nakagawa, Makoto Urano, Makoto Kuroda, Tomoyuki Shibata, Naoki Ohmiya
BACKGROUND: Gastric cancer develops after successful H. pylori eradication in patients with severe atrophic gastritis. We classified atrophic and non-atrophic mucosa of gastric body using magnifying NBI endoscopy in patients after successful H. pylori eradication. MATERIALS AND METHODS: One hundred and twenty-five patients after successful H. pylori eradication (median period after eradication: 36 months) were enrolled. Magnifying NBI patterns in the uninvolved gastric body were divided into the following: restored-small, round pits, accompanied with honeycomb-like subepithelial capillary networks; atrophic-well-demarcated oval or tubulovillous pits with clearly visible coiled or wavy vessels...
July 12, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28699598/role-of-toll-like-receptor-10-gene-polymorphism-and-gastric-mucosal-pattern-in-patients-with-chronic-gastritis
#8
Taweesak Tongtawee, Theeraya Bartpho, Wareeporn Wattanawongdon, Chavaboon Dechsukhum, Wilairat Leeanansaksiri, Likit Matrakool, Sukij Panpimanmas
BACKGROUND/AIMS: Helicobacter pylori stimulates the host's toll-like receptors (TLRs). Single-nucleotide polymorphism (SNP) of TLRs is related to the manipulation of regulatory cytokines and also implicated in the varied outcomes of the inflammatory response, including the development of precancerous lesions of gastric mucosa and disease progression. We hypothesized that TLR10 rs10004195 polymorphism is associated with gastric mucosal patterns. MATERIALS AND METHODS: TLR10 rs10004195 polymorphisms were identified in a total of 400 gastritis patients using the TagMan SNP genotyping assay...
July 2017: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/28698230/chromoendoscopy-versus-narrow-band-imaging-in-uc-a-prospective-randomised-controlled-trial
#9
Raf Bisschops, Talat Bessissow, Joseph A Joseph, Filip Baert, Marc Ferrante, Vera Ballet, Hilde Willekens, Ingrid Demedts, Karel Geboes, Gert De Hertogh, Séverine Vermeire, Paul Rutgeerts, Gert Van Assche
BACKGROUND: Patients with long-standing UC have an increased risk for the development of colonic neoplastic lesions. Chromoendoscopy (CE) has been proven to enhance neoplasia detection while the role of virtual chromoendoscopy (VC) is still to be defined. OBJECTIVE: To compare the performance of CE to VC for the detection of neoplastic lesions in patients with long-standing UC. DESIGN: A multicentre prospective randomised controlled trial...
July 11, 2017: Gut
https://www.readbyqxmd.com/read/28698099/bioinformatics-in-the-plant-genomic-and-phenomic-domain-the-german-contribution-to-resources-services-and-perspectives
#10
Thomas Schmutzer, Marie E Bolger, Stephen Rudd, Jinbo Chen, Heidrun Gundlach, Daniel Arend, Markus Oppermann, Stephan Weise, Matthias Lange, Manuel Spannagl, Björn Usadel, Klaus F X Mayer, Uwe Scholz
Plant genetic resources are a substantial opportunity for plant breeding, preservation and maintenance of biological diversity. As part of the German Network for Bioinformatics Infrastructure (de.NBI) the German Crop BioGreenformatics Network (GCBN) focuses mainly on crop plants and provides both data and software infrastructure which are tailored to the needs of the plant research community. Our mission and key objectives include: (1) provision of transparent access to germplasm seeds, (2) the delivery of improved workflows for plant gene annotation, and (3) implementation of bioinformatics services that link genotypes and phenotypes...
July 8, 2017: Journal of Biotechnology
https://www.readbyqxmd.com/read/28693176/flexible-magnifying-endoscopy-with-narrow-band-imaging-for-the-diagnosis-of-uterine-cervical-tumors-a-cooperative-study-among-gastrointestinal-endoscopists-and-gynecologists-to-explore-a-novel-microvascular-classification-system
#11
Noriko Nishiyama, Kenji Kanenishi, Hirohito Mori, Hideki Kobara, Shintaro Fujihara, Taiga Chiyo, Nobuya Kobayashi, Tae Matsunaga, Maki Ayaki, Tatsuo Yachida, Ayako Fujimori, Makoto Oryu, Chiaki Tenkumo, Megumi Ishibashi, Uiko Hanaoka, Toshiyuki Hata, Yumi Miyai, Kyuichi Kadota, Reiji Haba, Tsutomu Masaki
Narrow band imaging with magnifying endoscopy (NBI-ME), which is useful for the assessment of micro-vessels, has excellent diagnostic potential for early gastrointestinal epithelial neoplasia. Conventional diagnostic tools for uterine cervical epithelial tumors are still unsatisfactory. An accurate diagnostic tool for uterine cervical epithelial tumors is required to preserve the reproductive ability of young women with uterine cervical tumors. Flexible NBI-ME was performed in patients with cervical squamous cell lesions that required further examinations based on their Pap smear results (cytology ≥ low-grade squamous intraepithelial lesion) at Kagawa University Hospital between April 2014 and April 2015...
July 2017: Oncology Letters
https://www.readbyqxmd.com/read/28687028/adjunctive-use-of-chromoendoscopy-may-improve-the-diagnostic-performance-of-narrow-band-imaging-for-small-sessile-serrated-adenoma-polyp
#12
Li-Chun Chang, Chia-Hung Tu, Been-Ren Lin, Chia-Tung Shun, Weng-Feng Hsu, Jin-Tung Liang, Hsiu-Po Wang, Ming-Shiang Wu, Han-Mo Chiu
BACKGROUND AND AIMS: Endoscopic diagnosis of sessile serrated adenomas/polyps (SSA/P) is challenging because of their subtle appearance. Narrow-band imaging (NBI) is useful for diagnosis, but its utility with concurrent chromoendoscopy (CE), especially to detect small SSA/P, is unproven. PATIENTS AND METHODS: This prospective study enrolled 367 consecutive patients who underwent screening colonoscopy with the finding of serrated polyps. Patients were divided into derivation and validation cohorts: Diagnostic criteria using different endoscopic modalities were generated by regression analysis in the derivation cohort and were validated in the validation cohort for sensitivity, specificity, and accuracy...
July 7, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28676234/computational-proteomics-tools-for-identification-and-quality-control
#13
Dominik Kopczynski, Albert Sickmann, Robert Ahrends
Computational proteomics is a constantly growing field to support end users with powerful and reliable tools for performing several computational steps within an analytics workflow for proteomics experiments. Typically, after capturing with a mass spectrometer, the proteins have to be identified and quantified. After certain follow-up analyses, an optional targeted approach is suitable for validating the results. The de.NBI (German network for bioinformatics infrastructure) service center in Dortmund provides several software applications and platforms as services to meet these demands...
July 1, 2017: Journal of Biotechnology
https://www.readbyqxmd.com/read/28662209/narrow-band-imaging-nbi-for-improving-the-assessment-of-vocal-fold-leukoplakia-and-overcoming-the-umbrella-effect
#14
H Klimza, J Jackowska, M Tokarski, K Piersiala, M Wierzbicka
BACKGROUND: It is crucial to find a balance between functional and oncological outcome when choosing an adequate method for the management of vocal fold leukoplakia. Therefore, a detailed examination is a milestone in the decision-making process. AIM: To examine whether narrow-band imaging (NBI) can be helpful in vocal fold assessment in the case of leukoplakia and how to overcome the "umbrella effect"- understood as the submucosal vascular pattern hidden under the plaque...
2017: PloS One
https://www.readbyqxmd.com/read/28640478/usefulness-of-office-examination-with-narrow-band-imaging-for-the-diagnosis-of-head-and-neck-squamous-cell-carcinoma-and-follow-up-of-premalignant-lesions
#15
Isabel Vilaseca, Meritxell Valls-Mateus, Anna Nogués, Eduardo Lehrer, Mauricio López-Chacón, Francesc Xavier Avilés-Jurado, José Luis Blanch, Manuel Bernal-Sprekelsen
BACKGROUND: The purpose of this study was to evaluate the value of narrow band imaging (NBI) examination in the office for the diagnosis and follow-up of upper airway premalignant and malignant lesions. METHODS: Four hundred eighty lesions were evaluated with white light endoscopy (WLE) and NBI before a biopsy/excision. Additionally, 151 premalignant lesions were followed up without proven biopsy. Carcinoma-free survival was calculated. The learning curve was analyzed...
June 22, 2017: Head & Neck
https://www.readbyqxmd.com/read/28639135/histological-verification-of-the-usefulness-of-magnifying-endoscopy-with-narrow-band-imaging-for-horizontal-margin-diagnosis-of-differentiated-type-early-gastric-cancers
#16
Makomo Makazu, Kingo Hirasawa, Chiko Sato, Ryosuke Ikeda, Takehide Fukuchi, Yasuaki Ishii, Ryosuke Kobayashi, Hiroaki Kaneko, Masataka Taguri, Yoko Tateishi, Yoshiaki Inayama, Shin Maeda
BACKGROUND: Although magnifying endoscopy with narrow-band imaging (ME-NBI) can help identify the horizontal margin (HM) of early gastric cancer (EGC), little is known about the factors that can clarify the HM by using ME-NBI. We aimed to characterize the pathological features of lesions in which the HM was identified using ME-NBI. METHODS: The HMs of 639 differentiated-type EGCs treated with endoscopic submucosal dissection or surgery were analyzed using conventional endoscopy and ME-NBI...
June 21, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/28637065/evaluation-of-an-e-learning-system-for-diagnosis-of-gastric-lesions-using-magnifying-narrow-band-imaging-a-multicenter-randomized-controlled-study
#17
Hiroyoshi Nakanishi, Hisashi Doyama, Hideki Ishikawa, Noriya Uedo, Takuji Gotoda, Mototsugu Kato, Shigeaki Nagao, Yasuaki Nagami, Hiroyuki Aoyagi, Atsushi Imagawa, Junichi Kodaira, Shinya Mitsui, Nozomu Kobayashi, Manabu Muto, Hajime Takatori, Takashi Abe, Masahiko Tsujii, Jiro Watari, Shuhei Ishiyama, Ichiro Oda, Hiroyuki Ono, Kazuhiro Kaneko, Chizu Yokoi, Tetsuya Ueo, Kunihisa Uchita, Kenshi Matsumoto, Takashi Kanesaka, Yoshinori Morita, Shinichi Katsuki, Jun Nishikawa, Katsuhisa Inamura, Tetsu Kinjo, Katsumi Yamamoto, Daisuke Yoshimura, Hiroshi Araki, Hiroshi Kashida, Ayumu Hosokawa, Hirohito Mori, Haruhiro Yamashita, Osamu Motohashi, Kazuhiko Kobayashi, Michiaki Hirayama, Hiroyuki Kobayashi, Masaki Endo, Hiroo Yamano, Kazunari Murakami, Tomoyuki Koike, Kingo Hirasawa, Youichi Miyaoka, Hidetaka Hamamoto, Takuto Hikichi, Norihiro Hanabata, Ryo Shimoda, Shinichiro Hori, Tadashi Sato, Shinya Kodashima, Hiroyuki Okada, Tomohiko Mannami, Shojiro Yamamoto, Yasumasa Niwa, Kazuo Yashima, Satoshi Tanabe, Hiro Satoh, Fumisato Sasaki, Tetsuro Yamazato, Yoshiou Ikeda, Hogara Nishisaki, Masahiro Nakagawa, Akio Matsuda, Fumio Tamura, Hitoshi Nishiyama, Keiko Arita, Keisuke Kawasaki, Kazushige Hoppo, Masashi Oka, Shinichi Ishihara, Michita Mukasa, Hiroaki Minamino, Kenshi Yao
Background and study aim Magnifying narrow-band imaging (M-NBI) is useful for the accurate diagnosis of early gastric cancer (EGC). However, acquiring skill at M-NBI diagnosis takes substantial effort. An Internet-based e-learning system to teach endoscopic diagnosis of EGC using M-NBI has been developed. This study evaluated its effectiveness. Participants and methods This study was designed as a multicenter randomized controlled trial. We recruited endoscopists as participants from all over Japan. After completing Test 1, which consisted of M-NBI images of 40 gastric lesions, participants were randomly assigned to the e-learning or non-e-learning groups...
June 21, 2017: Endoscopy
https://www.readbyqxmd.com/read/28625679/phenotype-databases-for-genetic-screens-in-human-cells
#18
Benedikt Rauscher, Erica Valentini, Ulrike Hardeland, Michael Boutros
Genetic screens are powerful tools to identify components that make up biological systems. Perturbations introduced by methods such as RNA interference (RNAi) or CRISPR/Cas9-mediated genome editing lead to biological phenotypes that can be examined to understand the molecular function of genes in the cell. Over the years, many of such experiments have been conducted providing a wealth of knowledge about genotype-to-phenotype relationships. These data are a rich source of information and it is in a common interest to make them available in a simplified and integrated format...
June 15, 2017: Journal of Biotechnology
https://www.readbyqxmd.com/read/28611665/toll-like-receptor-4-in-paraventricular-nucleus-mediates-visceral-hypersensitivity-induced-by-maternal-separation
#19
Hui-Li Tang, Gongliang Zhang, Ning-Ning Ji, Lei Du, Bin-Bin Chen, Rong Hua, Yong-Mei Zhang
Neonatal maternal separation (MS) is a major early life stress that increases the risk of emotional disorders, visceral pain perception and other brain dysfunction. Elevation of toll-like receptor 4 (TLR4) signaling in the paraventricular nucleus (PVN) precipitates early life colorectal distension (CRD)-induced visceral hypersensitivity and pain in adulthood. The present study aimed to investigate the role of TLR4 signaling in the pathogenesis of postnatal MS-induced visceral hypersensitivity and pain during adulthood...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28611445/insulin-like-growth-factor-i-and-its-binding-protein-3-are-regulators-of-lactation-and-maternal-responsiveness
#20
András H Lékó, Melinda Cservenák, Éva Rebeka Szabó, János Hanics, Alán Alpár, Árpád Dobolyi
Adaptation to motherhood includes maternal behaviour and lactation during the postpartum period. The major organizing centres of maternal behaviour and lactation are located in the hypothalamic medial preoptic area (MPOA) and the arcuate nucleus, respectively. Insulin-like growth factor I (IGF-I) is an effector of the growth hormone axis; however, its function in the brain is largely unexplored. We identified increased maternal IGF binding protein-3 (IGFBP-3) expression in preoptic rat microarray data and confirmed it by RT-PCR...
June 13, 2017: Scientific Reports
keyword
keyword
57353
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"