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https://www.readbyqxmd.com/read/27921066/review-of-imaging-network-activities-in-developing-rodent-cerebral-cortex-in-vivo
#1
REVIEW
Heiko J Luhmann
The combination of voltage-sensitive dye imaging (VSDI) with multielectrode array (MEA) recordings in the rodent cerebral cortex in vivo allows the simultaneous analysis of large-scale network interactions and electrophysiological single-unit recordings. Using this approach, distinct patterns of spontaneous and sensory-evoked activity can be recorded in the primary somatosensory (S1) and motor cortex (M1) of newborn rats. Already at the day of birth, gamma oscillations and spindle bursts in the barrel cortex synchronize the activity of a local columnar ensemble, thereby generating an early topographic representation of the sensory periphery...
July 2017: Neurophotonics
https://www.readbyqxmd.com/read/27920665/multiple-single-unit-long-term-tracking-on-organotypic-hippocampal-slices-using-high-density-microelectrode-arrays
#2
Wei Gong, Jure Senčar, Douglas J Bakkum, David Jäckel, Marie Engelene J Obien, Milos Radivojevic, Andreas R Hierlemann
A novel system to cultivate and record from organotypic brain slices directly on high-density microelectrode arrays (HD-MEA) was developed. This system allows for continuous recording of electrical activity of specific individual neurons at high spatial resolution while monitoring at the same time, neuronal network activity. For the first time, the electrical activity patterns of single neurons and the corresponding neuronal network in an organotypic hippocampal slice culture were studied during several consecutive weeks at daily intervals...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27916876/coriandrum-sativum-and-lavandula-angustifolia-essential-oils-chemical-composition-and-activity-on-central-nervous-system
#3
Lucia Caputo, Lucéia Fátima Souza, Susanna Alloisio, Laura Cornara, Vincenzo De Feo
The aims of this study are to determine the chemical composition of Lavandula angustifolia Mill. and Coriandrum sativum L. essential oils, to evaluate their cytotoxic effects in SH-SY5Y human neuroblastoma cells, to investigate whether an alteration of adenylate cyclase 1 (ADCY1) and of extracellular signal-regulated kinase (ERK) expression can take part in the molecular mechanisms of the essential oils, and to study their possible neuronal electrophysiological effects. The essential oils were obtained by hydrodistillation, and studied by GC and GC-MS...
November 30, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27915209/development-of-neural-population-activity-towards-self-organized-criticality
#4
Yuichiro Yada, Takeshi Mita, Akihiro Sanada, Ryuichi Yano, Ryohei Kanzaki, Douglas J Bakkum, Andreas Hierlemann, Hirokazu Takahashi
Self-organized criticality (SoC), a spontaneous dynamic state established and maintained in networks of moderate complexity, is a universal characteristic of neural systems. Such systems produce cascades of spontaneous activity that are typically characterized by power-law distributions and rich, stable spatiotemporal patterns (i.e., neuronal avalanches). Since the dynamics of the critical state confer advantages in information processing within neuronal networks, it is of great interest to determine how criticality emerges during development...
November 30, 2016: Neuroscience
https://www.readbyqxmd.com/read/27909417/defining-contemplative-science-the-metacognitive-self-regulatory-capacity-of-the-mind-context-of-meditation-practice-and-modes-of-existential-awareness
#5
Dusana Dorjee
The term 'contemplative' is now frequently used in the fast growing field of meditation research. Yet, there is no consensus regarding the definition of contemplative science. Meditation studies commonly imply that contemplative practices such as mindfulness or compassion are the subject of contemplative science. Such approach, arguably, contributes to terminological confusions in the field, is not conducive to the development of an overarching theory in contemplative science, and overshadows its unique methodological features...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27900618/3d-carbon-nanofiber-microelectrode-arrays-fabricated-by-plasma-assisted-pyrolysis-to-enhance-sensitivity-and-stability-of-real-time-dopamine-detection
#6
Wenwen Yi, Yuanyuan Yang, Parastoo Hashemi, Mark Ming-Cheng Cheng
In this paper, we have fabricated 3D carbon nanofiber microelectrode arrays (MEAs) with highly reproducible and rich chemical surface areas for fast scan cyclic voltammetry (FSCV). Carbon nanofibers are created from negative photoresist by a new process called dual O2 plasma-assisted pyrolysis. The proposed approach significantly improves film adhesion and increases surface reactivity. We showcase our sensor's compatibility with FSCV analysis by demonstrating highly sensitive and stable FSCV dopamine measurements on a prototype 4-channel array...
December 2016: Biomedical Microdevices
https://www.readbyqxmd.com/read/27900475/microclimatic-effects-of-planted-hydroponic-structures-in-urban-environment-measurements-and-simulations
#7
N Katsoulas, D Antoniadis, I L Tsirogiannis, E Labraki, T Bartzanas, C Kittas
The objectives of this effort was to study the effect of vertical (green wall) and horizontal (pergola) green structures on the microclimate conditions of the building surroundings and estimate the thermal perception and heat stress conditions near the two structures. The experimental data were used to validate the results simulated by the recent version (V4.0 preview III) of ENVI-met software which was used to simulate the effect of different design parameters of a pergola and a green façade on microclimate and heat stress conditions...
November 29, 2016: International Journal of Biometeorology
https://www.readbyqxmd.com/read/27862369/three-dimensional-interlocking-interface-mechanical-nanofastener-for-high-interfacial-robustness-of-polymer-electrolyte-membrane-fuel-cells
#8
Seongmin Yuk, Min-Ju Choo, Dongyoung Lee, Hwanuk Guim, Tae-Ho Kim, Dai Gil Lee, Sungyu Choi, Dong-Hyun Lee, Gisu Doo, Young Taik Hong, Hee-Tak Kim
A scalable nanofastener featuring a 3D interlocked interfacial structure between the hydrocarbon membrane and perfluorinated sulfonic acid based catalyst layer is presented to overcome the interfacial issue of hydrocarbon membrane based polymer electrolyte membrane fuel cells. The nanofastener-introduced membrane electrode assembly (MEA) withstands more than 3000 humidity cycles which is 20 times higher durability than that of MEA without nanofastener.
November 10, 2016: Advanced Materials
https://www.readbyqxmd.com/read/27836602/a-biomimetic-bioelectronic-tongue-a-switch-for-on-and-off-response-of-acid-sensations
#9
Wei Zhang, Peihua Chen, Lianqun Zhou, Zhen Qin, Keqiang Gao, Jia Yao, Chuanyu Li, Ping Wang
The perception of sour taste in mammals is important for its basic modality properties and avoiding toxic substances. We explore a biomimetic bioelectronic tongue, which integrate MEA (microelectrode array) and taste receptor cell for acid detection as a switch. However, the acid-sensing mechanism and coding of the taste receptor cells in the periphery is not well understood, with long-standing debate. Therefore, we firstly construct a Hodgkin-Huxley type mathematical model of whole-cell acid-sensing taste receptor cells based on the electrophysiologic patch clamp recordings with different acid sensitive receptor expressing and different acidic stimulations...
October 27, 2016: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27814869/neurodynamic-treatment-for-patients-with-nerve-related-leg-pain-protocol-for-a-randomized-controlled-trial
#10
Giovanni E Ferreira, Fábio F Stieven, Francisco X Araújo, Matheus Wiebusch, Carolina G Rosa, Rodrigo Della Méa Plentz, Marcelo F Silva
OBJECTIVES: To investigate if neurodynamic treatment is more effective than advice to remain active in patients with nerve-related leg pain. DESIGN: Parallel-group randomized controlled trial blinded to the outcome assessor conducted in Porto Alegre, Brazil. PARTICIPANTS: Sixty patients recruited from the community and private practices. INTERVENTION: Patients will be randomly assigned to receive four sessions of neurodynamic treatment over two weeks comprising passive lumbar foramen opening and neurodynamic sliders plus home exercises or advice to remain active...
October 2016: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/27812002/on-chip-multisite-extracellular-and-intracellular-recordings-from-primary-cultured-skeletal-myotubes
#11
Noha Rabieh, Silviya M Ojovan, Nava Shmoel, Hadas Erez, Eilon Maydan, Micha E Spira
In contrast to the extensive use of microelectrode array (MEA) technology in electrophysiological studies of cultured neurons and cardiac muscles, the vast field of skeletal muscle research has yet to adopt the technology. Here we demonstrate an empowering MEA technology for high quality, multisite, long-term electrophysiological recordings from cultured skeletal myotubes. Individual rat skeletal myotubes cultured on micrometer sized gold mushroom-shaped microelectrode (gMμE) based MEA tightly engulf the gMμEs, forming a high seal resistance between the myotubes and the gMμEs...
November 4, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27811971/high-performance-palladium-supported-on-nanoporous-carbon-under-anhydrous-condition
#12
Zehui Yang, Ying Ling, Yunfeng Zhang, Guodong Xu
Due to the high cost of polymer electrolyte fuel cells (PEFCs), replacing platinum (Pt) with some inexpensive metal was carried out. Here, we deposited palladium nanoparticles (Pd-NPs) on nanoporous carbon (NC) after wrapping by poly[2,2'-(2,6-pyridine)-5,5'-bibenzimidazole] (PyPBI) doped with phosphoric acid (PA) and the Pd-NPs size was successfully controlled by varying the weight ratio between Pd precursor and carbon support doped with PA. The membrane electrode assembly (MEA) fabricated from the optimized electrocatalyst with 0...
November 4, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27811080/fie-a-nuclear-prc2-protein-forms-cytoplasmic-complexes-in-arabidopsis-thaliana
#13
Moran Oliva, Yana Butenko, Tzung-Fu Hsieh, Ofir Hakim, Aviva Katz, Nechama I Smorodinsky, Daphna Michaeli, Robert L Fischer, Nir Ohad
Polycomb group (PcG) proteins are evolutionarily conserved chromatin modifiers that regulate developmental pathways in plants. PcGs form nuclear multi-subunit Polycomb Repressive Complexes (PRCs). The PRC2 complex mediates gene repression via methylation of lysine 27 on histone H3, which consequently leads to chromatin condensation. In Arabidopsis thaliana, several PRC2 complexes with different compositions were identified, each controlling a particular developmental program.The core subunit FIE is crucial for PRC2 function throughout the plant life cycle, yet accurate information on its spatial and temporal localization was absent...
November 2016: Journal of Experimental Botany
https://www.readbyqxmd.com/read/27809540/chemisorption-of-hydroxide-on-2d-materials-from-dft-calculations-graphene-versus-hexagonal-boron-nitride
#14
Benoit Grosjean, Clarisse Péan, Alessandro Siria, Lyderic Bocquet, Rodolphe Vuilleumier, Marie-Laure Bocquet
Recent nanofluidic measurements revealed strongly different surface charge mea- surements for boron-nitride and graphitic nanotubes when in contact with saline and alkaline water.1,2 These observations contrast with the similar reactivity of a graphene layer and its boron nitride counterpart, using Density Functional Theory (DFT) frame- work, for intact and dissociative adsorption of gaseous water molecules. Here, we in- vestigate by DFT in implicit water single and multiple adsorption of anionic hydroxide on single layers...
November 3, 2016: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/27805788/the-stability-challenges-of-oxygen-evolving-electrocatalysts-towards-a-common-fundamental-understanding-and-mitigation-of-catalyst-degradation
#15
Camillo Spoeri, Jason Tai Hong Kwan, Arman Bonakdarpour, David Wilkinson, Peter Strasser
The electrochemical oxygen evolution reaction (OER) is an important reaction in the industrial production of numerous inorganic chemicals. However, over the last decade it has also received growing attention as scalable proton- and electron-providing process for use in the production of solar fuels, such as hydrogen, hydrocarbons, or alcohols carried out in water- and CO2-electrolyzers. To operate these devices efficiently and economically , active and stable electrocatalysts are required. While advances have been made in understanding and tuning OER efficiency and activity, the stability of OER catalysts and the reduction of their degradation continue to be major challenges...
November 1, 2016: Angewandte Chemie
https://www.readbyqxmd.com/read/27805613/spiral-ganglion-neuron-explant-culture-and-electrophysiology-on-multi-electrode-arrays
#16
Stefan Hahnewald, Marta Roccio, Anne Tscherter, Jürg Streit, Ranjeeta Ambett, Pascal Senn
Spiral ganglion neurons (SGNs) participate in the physiological process of hearing by relaying signals from sensory hair cells to the cochlear nucleus in the brain stem. Loss of hair cells is a major cause of sensory hearing loss. Prosthetic devices such as cochlear implants function by bypassing lost hair cells and directly stimulating SGNs electrically, allowing for restoration of hearing in deaf patients. The performance of these devices depends on the functionality of SGNs, the implantation procedure and on the distance between the electrodes and the auditory neurons...
October 19, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27803660/spectral-entropy-based-neuronal-network-synchronization-analysis-based-on-microelectrode-array-measurements
#17
Fikret E Kapucu, Inkeri Välkki, Jarno E Mikkonen, Chiara Leone, Kerstin Lenk, Jarno M A Tanskanen, Jari A K Hyttinen
Synchrony and asynchrony are essential aspects of the functioning of interconnected neuronal cells and networks. New information on neuronal synchronization can be expected to aid in understanding these systems. Synchronization provides insight in the functional connectivity and the spatial distribution of the information processing in the networks. Synchronization is generally studied with time domain analysis of neuronal events, or using direct frequency spectrum analysis, e.g., in specific frequency bands...
2016: Frontiers in Computational Neuroscience
https://www.readbyqxmd.com/read/27802592/poss-containing-bioinspired-adhesives-with-enhanced-mechanical-and-optical-properties-for-biomedical-applications
#18
Irawan Pramudya, Catalina Gomez Rico, Choogon Lee, Hoyong Chung
A new terpolymer adhesive, poly(2-methoxyethyl acrylate-co-N-methacryloyl 3,4-dihydroxyl-L-phenylalanine-co-heptaisobutyl substituted polyhedral oligomeric silsesquioxane propylmethacrylate) (poly(MEA-co-MDOPA-co-MPOSS) was synthesized by thermally initiated radical polymerization. In this study, we investigated the effect of the POSS component on adhesion, mechanical, and optical properties of the catechol-group containing bioinspired adhesives. The terpolymer contains the catechol group which is known to improve the adhesion properties of polymers...
November 1, 2016: Biomacromolecules
https://www.readbyqxmd.com/read/27800146/antimicrobial-activity-of-biocompatible-microemulsions-against-aspergillus-niger-and-herpes-simplex-virus-type-2
#19
Mayson H Alkhatib, Magda M Aly, Rajaa A Rahbeni, Khadijah S Balamash
BACKGROUND: Microemulsions (MEs), which consist of oil, water, surfactants, and cosurfactants, have recently generated considerable interest as antimicrobial agents. OBJECTIVES: To determine the antifungal and antiviral activities of three ME formulations (MEa, MEb, and MEc) that differ in their hydrophilicity. METHODS: The ME formulas were produced by mixing different fractions of Tween 80, Span 20, ethanol, oil, isopropyl myristate, and distilled water...
September 2016: Jundishapur Journal of Microbiology
https://www.readbyqxmd.com/read/27793779/a-food-predictive-cue-attributed-with-incentive-salience-engages-subcortical-afferents-and-efferents-of-the-paraventricular-nucleus-of-the-thalamus
#20
Joshua L Haight, Zachary L Fuller, Kurt M Fraser, Shelly B Flagel
The paraventricular nucleus of the thalamus (PVT) has been implicated in behavioral responses to reward-associated cues. However, the precise role of the PVT in these behaviors has been difficult to ascertain since Pavlovian-conditioned cues can act as both predictive and incentive stimuli. The "sign-tracker/goal-tracker" rat model has allowed us to further elucidate the role of the PVT in cue-motivated behaviors, identifying this structure as a critical component of the neural circuitry underlying individual variation in the propensity to attribute incentive salience to reward cues...
October 25, 2016: Neuroscience
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