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https://www.readbyqxmd.com/read/28547835/application-of-omentum-as-an-in-vivo-bioreactor-for-regeneration-of-decellularized-human-internal-mammary-artery
#1
Reza Khorramirouz, Maryam Kameli, Sahar Eftekharzadeh, Abdol-Mohammad Kajbafzadeh
This study investigates the extent of cell seeding as well as lumen patency in acellular Internal mammary artery (IMA) scaffolds that have been re-cellularized by omentum as a natural bioreactor. Sixteen Virgin female Wistar rats were selected for implantation of acellular scaffold in omentum. Following laparotomy omentum was retracted to the outside of the abdomen and the more vascularized portion of it was selected for the experiment. The scaffold was wrapped by omentum and placed between two layers of rectus muscles that have been previously dissected...
May 25, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28544610/phenol-enriched-olive-oils-modify-paraoxonase-related-variables-a-randomized-crossover-controlled-trial
#2
Sara Fernández-Castillejo, Ana-Isabel García-Heredia, Rosa Solà, Jordi Camps, Maria-Carmen López de la Hazas, Marta Farràs, Anna Pedret, Úrsula Catalan, Laura Rubió, Maria-José Motilva, Olga Castañer, María-Isabel Covas, Rosa-Maria Valls
SCOPE: Low paraoxonase (PON)1 activities, and high PON1 and low PON3 protein levels are characteristic of cardiovascular disease. Our aim was to assess short and long-term effects of virgin olive oils (VOO), enriched with their own phenolic compounds (PC; FVOO) or with them plus complementary PC from thyme (FVOOT), on PON-related variables and the mechanisms involved. METHODS AND RESULTS: Two randomized, controlled, double-blind, and crossover interventions were conducted...
May 25, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28542189/mir-277-4989-regulate-transcriptional-landscape-during-juvenile-to-adult-transition-in-the-parasitic-helminth-schistosoma-mansoni
#3
Anna V Protasio, Stijn van Dongen, Julie Collins, Leonor Quintais, Diogo M Ribeiro, Florian Sessler, Martin Hunt, Gabriel Rinaldi, James J Collins, Anton J Enright, Matthew Berriman
Schistosomes are parasitic helminths that cause schistosomiasis, a disease affecting circa 200 million people, primarily in underprivileged regions of the world. Schistosoma mansoni is the most experimentally tractable schistosome species due to its ease of propagation in the laboratory and the high quality of its genome assembly and annotation. Although there is growing interest in microRNAs (miRNAs) in trematodes, little is known about the role these molecules play in the context of developmental processes...
May 23, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28540463/investigating-the-organic-and-conventional-production-type-of-olive-oil-with-target-and-suspect-screening-by-lc-qtof-ms-a-novel-semi-quantification-method-using-chemical-similarity-and-advanced-chemometrics
#4
Natasa P Kalogiouri, Reza Aalizadeh, Nikolaos S Thomaidis
The discrimination of organic and conventional production has been a critical topic of public discussion and constitutes a scientific issue. It remains a challenge to establish a correlation between the agronomical practices and their effects on the composition of olive oils, especially the phenolic composition, since it defines their organoleptic and nutritional value. Thus, a liquid chromatography-electrospray ionization-quadrupole time of flight tandem mass spectrometric method was developed, using target and suspect screening workflows, coupled with advanced chemometrics for the identification of phenolic compounds and the discrimination between organic and conventional extra virgin olive oils...
May 25, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28538813/mechanisms-of-endothelial-protection-by-natural-bioactive-compounds-from-fruit-and-vegetables
#5
Bernardita Monsalve, Anibal Concha-Meyer, Iván Palomo, Eduardo Fuentes
The endothelium is fundamental for the regulation of vascular tone and structure. Under disease conditions, including the presence of cardiovascular disease risk factors, the endothelium loses its protective role and becomes a proatherosclerotic structure. In this article we searched for strategies from PUBMED and Science Direct databases using the following key words: endothelium, natural bioactive compounds, polyphenols and cardiovascular diseases. The search was restricted to english language papers. Studies have identified the contribution of diet to the risk of developing cardiovascular diseases...
May 22, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28536987/sexual-deception-in-the-eucera-pollinated-ophrys-leochroma-a-chemical-intermediate-between-wasp-and-andrena-pollinated-species
#6
Monica Cuervo, Demetra Rakosy, Carlos Martel, Stefan Schulz, Manfred Ayasse
Ophrys flowers mimic sex pheromones of attractive females of their pollinators and attract males, which attempt to copulate with the flower and thereby pollinate it. Virgin females and orchid flowers are known to use the same chemical compounds in order to attract males. The composition of the sex pheromone and its floral analogue, however, vary between pollinator genera. Wasp-pollinated Ophrys species attract their pollinators by using polar hydroxy acids, whereas Andrena-pollinated species use a mixture of non-polar hydrocarbons...
May 23, 2017: Journal of Chemical Ecology
https://www.readbyqxmd.com/read/28536589/the-role-of-polyphenoloxidase-peroxidase-and-%C3%AE-glucosidase-in-phenolics-accumulation-in-olea-europaea-l-fruits-under-different-water-regimes
#7
Marco Cirilli, Giovanni Caruso, Clizia Gennai, Stefania Urbani, Eleonora Frioni, Maurizio Ruzzi, Maurizio Servili, Riccardo Gucci, Elia Poerio, Rosario Muleo
Olive fruits and oils contain an array of compounds that contribute to their sensory and nutritional properties. Phenolic compounds in virgin oil and olive-derived products have been proven to be highly beneficial for human health, eliciting increasing attention from the food industry and consumers. Although phenolic compounds in olive fruit and oil have been extensively investigated, allowing the identification of the main classes of metabolites and their accumulation patterns, knowledge of the molecular and biochemical mechanisms regulating phenolic metabolism remains scarce...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28536360/coconut-cocos-nucifera-ethanolic-leaf-extract-reduces-amyloid-%C3%AE-1-42-aggregation-and-paralysis-prevalence-in-transgenic-caenorhabditis-elegans-independently-of-free-radical-scavenging-and-acetylcholinesterase-inhibition
#8
Rafael Vincent Manalo, Maries Ann Silvestre, Aza Lea Anne Barbosa, Paul Mark Medina
Virgin coconut oil (VCO) has been the subject of several studies which have aimed to alleviate Alzheimer's disease (AD) pathology, focusing on in vitro antioxidant and acetylcholinesterase (AChE) inhibitory activities. Here, we studied an underutilized and lesser-valued part of the coconut tree, specifically the leaves, using in vitro and in vivo approaches. Coconut leaf extract (CLE) was screened for antioxidant and AChE inhibitory properties in vitro and therapeutic effects in two strains of transgenic Caenorhabditis elegans expressing amyloid-β1-42 (Aβ1-42) in muscle cells...
April 21, 2017: Biomedicines
https://www.readbyqxmd.com/read/28532621/an-experimental-study-on-thermo-catalytic-pyrolysis-of-plastic-waste-using-a-continuous-pyrolyser
#9
Anthony R Auxilio, Wei-Lit Choo, Isha Kohli, Srikanth Chakravartula Srivatsa, Sankar Bhattacharya
A bench scale, two-stage, thermo-catalytic reactor equipped with a continuous feeding system was used to pyrolyse pure and waste plastics. Experiments using five zeolitic and clay-based catalysts of different forms (pellet and powders) and different plastic feedstocks - virgin HDPE, HDPE w1aste and mixed plastic waste (MPW) were compared to the control experiments - pyrolysis without catalyst. Results indicated that the two pelletized catalysts were the most promising for the conditions employed. Of these two, one with higher acidity and surface area was highly selective for the gasoline fraction (C5-C11) giving 80% from the total medium distillate conversion using virgin HDPE as feedstock...
May 19, 2017: Waste Management
https://www.readbyqxmd.com/read/28528136/the-management-of-the-acute-ischemic-priapism-a-state-of-the-art-review
#10
M Falcone, A Gillo, M Capece, A Raheem, D Ralph, G Garaffa
OBJECTIVE: To review the current literature on early penile prosthesis implantation in patients with refractory ischemic priapism (IP). ACQUISITION OF EVIDENCE: A systematic search for the terms "penile prosthesis", "priapism", "impotence", "fibrosis", "downsized prosthesis cylinders", and "patient satisfaction" has been carried out in PubMed, EMBASE, Cochrane, SCOPUS and Science Citation Index databases. SYNTHESIS OF EVIDENCE: Cavernosal tissue damage in IP is time related...
May 17, 2017: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/28526925/polyphenolic-extract-attenuates-fatty-acid-induced-steatosis-and-oxidative-stress-in-hepatic-and-endothelial-cells
#11
Laura Vergani, Giulia Vecchione, Francesca Baldini, Elena Grasselli, Adriana Voci, Piero Portincasa, Pier Francesco Ferrari, Bahar Aliakbarian, Alessandro A Casazza, Patrizia Perego
PURPOSE: Phenolic compounds (PC) of virgin olive oil exert several biochemical and pharmacological beneficial effects. Some dietary PC seem to prevent/improve obesity and metabolic-related disorders such as non-alcoholic fatty liver disease (NAFLD). We investigated the possible effects of PC extracted from olive pomace (PEOP) and of the main single molecules present in the extract (tyrosol, apigenin, oleuropein, p-coumaric and caffeic acid) in protecting hepatocytes and endothelial cells against triglyceride accumulation and oxidative stress...
May 19, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28525510/zika-virus-obstetric-and-pediatric-anesthesia-considerations
#12
Jacqueline L Tutiven, Benjamin T Pruden, James S Banks, Mario Stevenson, David J Birnbach
As of November 2016, the Florida Department of Health (FDH) and the Centers for Disease Control and Prevention have confirmed more than 4000 travel-related Zika virus (ZIKV) infections in the United States with >700 of those in Florida. There have been 139 cases of locally acquired infection, all occurring in Miami, Florida. Within the US territories (eg, Puerto Rico, US Virgin Islands), >30,000 cases of ZIKV infection have been reported. The projected number of individuals at risk for ZIKV infection in the Caribbean and Latin America approximates 5 million...
June 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28522404/tubo-ovarian-abscess-in-a-virginal-adolescent-with-labial-agglutination-due-to-lichen-sclerosus
#13
Bianca Stortini, Ozlem Dural, Maria Kielly, Nathalie Fleming
BACKGROUND: We describe an unusual presentation of lichen sclerosus in a postmenarchal, virginal girl. CASE: A 14 year-old girl first presented with acute urinary retention due to labial agglutination and developed bilateral tubo-ovarian abscesses in 10 days of the conservative management period. Abscesses were treated with antibiotherapy and percutaneous drainage; simple division of the labial agglutination and vulvar biopsies were performed with a preliminary diagnosis of lichen sclerosus...
May 15, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/28521813/virginity-testing-a-systematic-review
#14
REVIEW
Rose McKeon Olson, Claudia García-Moreno
BACKGROUND: So-called virginity testing, also referred to as hymen, two-finger, or per vaginal examination, is the inspection of the female genitalia to assess if the examinee has had or has been habituated to sexual intercourse. This paper is the first systematic review of available evidence on the medical utility of virginity testing by hymen examination and its potential impacts on the examinee. METHODS: Ten electronic databases and other sources for articles published in English were systematically searched from database inception until January 2017...
May 18, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28516946/ccl2-ccr2-signalling-recruits-a-distinct-fetal-microchimeric-population-that-rescues-delayed-maternal-wound-healing
#15
Mathieu Castela, Dany Nassar, Maria Sbeih, Marie Jachiet, Zhe Wang, Selim Aractingi
Foetal microchimeric cells (FMCs) traffic into maternal circulation during pregnancy and persist for decades after delivery. Upon maternal injury, FMCs migrate to affected sites where they participate in tissue healing. However, the specific signals regulating the trafficking of FMCs to injury sites had to be identified. Here we report that, in mice, a subset of FMCs implicated in tissue repair displays CD11b(+) CD34(+) CD31(+) phenotype and highly express C-C chemokine receptor 2 (Ccr2). The Ccr2 ligand chemokine ligand 2 (Ccl2) enhances the recruitment of FMCs to maternal wounds where these cells transdifferentiate into endothelial cells and stimulate angiogenesis through Cxcl1 secretion...
May 18, 2017: Nature Communications
https://www.readbyqxmd.com/read/28515877/sex-specific-repeatabilities-and-effects-of-relatedness-and-mating-status-on-copulation-duration-in-an-acridid-grasshopper
#16
Michael Haneke-Reinders, Klaus Reinhold, Tim Schmoll
In species with direct sperm transfer, copulation duration is a crucial trait that may affect male and female reproductive success and that may vary with the quality of the mating partner. Furthermore, traits such as copulation duration represent the outcome of behavioral interactions between the sexes, for which it is important-but often difficult-to determine which sex is in phenotypic control. Using a double-mating protocol, we compared copulation durations between (1) virgin and nonvirgin and (2) sibling and nonsibling mating pairs in rufous grasshoppers Gomphocerippus rufus...
May 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28511862/effect-of-different-concentrations-of-egg-yolk-and-virgin-coconut-oil-in-tris-based-extenders-on-chilled-and-frozen-thawed-bull-semen
#17
A A Tarig, H Wahid, Y Rosnina, N Yimer, Y M Goh, F H Baiee, A M Khumran, H Salman, M Ebrahimi
The aim of this study was to evaluate the effects of 8% virgin coconut oil (VCO) combined with different percentages of egg yolk in Tris extender on the quality of chilled and frozen-thawed bull semen. A total of 24 ejaculates from four bulls were collected using an electroejaculator. Semen samples were diluted with 8% VCO in Tris extender which contained different concentrations 0% (control), 4%, 8%, 12%, 16% and 20% egg yolk. The diluted semen samples were divided into two fractions: one was chilled and stored at 4°C until evaluation after 24, 72, and 144h; the second fraction was processed by chilling for 3h at 4°C to equilibrate, then packaged in 0...
April 10, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/28506669/recycling-and-characterization-of-carbon-fibers-from-carbon-fiber-reinforced-epoxy-matrix-composites-by-a-novel-super-heated-steam-method
#18
Kwan-Woo Kim, Hye-Min Lee, Jeong-Hun An, Dong-Chul Chung, Kay-Hyeok An, Byung-Joo Kim
In order to manufacture high quality recycled carbon fibers (R-CFs), carbon fiber-reinforced composite wastes were pyrolysed with super-heated steam at 550 °C in a fixed bed reactor for varying reaction times. The mechanical and surface properties of the R-CFs were characterized with a single fiber tensile test, interface shear strength (IFSS), scanning electron microscopy (SEM), and X-ray photoelectron spectroscopy (XPS). The surface analysis showed that there was no matrix char residue on the fiber surfaces...
May 12, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28502868/no-pain-no-gain-male-plasticity-in-burrow-digging-according-to-female-rejection-in-a-sand-dwelling-wolf-spider
#19
Matilde Carballo, Fabiana Baldenegro, Fedra Bollatti, Alfredo V Peretti, Anita Aisenberg
Behavioral plasticity allows individuals to reversibly respond to short-term variations in their ecological and social environment in order to maximize their fitness. Allocosa senex is a burrow-digging spider that inhabits the sandy coasts of South America. This species shows a reversal in typical sex roles expected in spiders: females are wanderers that visit males at their burrows and initiate courtship. They prefer males with long burrows for mating, and males prefer virgin over mated females. We tested whether female sexual rejection induced males to enlarge their burrows and if female reproductive status affected males' responses...
May 11, 2017: Behavioural Processes
https://www.readbyqxmd.com/read/28499884/inhibition-of-ubiquitin-specific-protease-34-usp34-induces-epithelial-mesenchymal-transition-and-promotes-stemness-in-mammary-epithelial-cells
#20
Eunhye Oh, Ji Young Kim, Daeil Sung, Youngkwan Cho, Nahyun Lee, Hyunsook An, Yoon-Jae Kim, Tae-Min Cho, Jae Hong Seo
Ubiquitin-specific protease 34 (USP34) is a deubiquitinating enzyme that regulates Axin stability and plays a critical role in Wnt/β-catenin signaling. We sought to investigate the role of USP34 on epithelial-mesenchymal (EMT) induction and its effects on mammary epithelial stem cells. USP34 expression levels were relatively lower in MDA-MB-231 and 4T1 mesenchymal-like cells when compared to epithelial-like cells. Inhibition of USP34 in NMuMG cells induced EMT, as evidenced by the upregulation of EMT markers including N-cadherin, phospho-Smad3, Snail and active-β-catenin, as well as the downregulation of Axin 1 and E-cadherin...
May 10, 2017: Cellular Signalling
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