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https://www.readbyqxmd.com/read/28212439/correction-type-i-interferon-receptor-deficiency-in-dendritic-cells-facilitates-systemic-murine-norovirus-persistence-despite-enhanced-adaptive-immunity
#1
Timothy J Nice, Lisa C Osborne, Vesselin T Tomov, David Artis, E John Wherry, Herbert W Virgin
[This corrects the article DOI: 10.1371/journal.ppat.1005684.].
February 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28211122/prolactin-regulation-of-oxytocin-neurone-activity-in-pregnancy-and-lactation
#2
Rachael A Augustine, Sharon R Ladyman, Gregory T Bouwer, Yousif Alyousif, Tony J Sapsford, Victoria Scott, Ilona C Kokay, David R Grattan, Colin H Brown
Secretion of prolactin for milk synthesis and oxytocin for milk secretion is required for successful lactation. In virgin rats, prolactin inhibits oxytocin neurones but this effect would be counterproductive during lactation when secretion of both hormones is required for synthesis and delivery of milk to the new-born. Hence, we determined the effects of intracerebroventricular (ICV) prolactin on oxytocin neurones in urethane-anaesthetised virgin, pregnant and lactating rats. Prolactin (2 μg) consistently inhibited oxytocin neurones in virgin and pregnant rats (by 1...
February 17, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28198144/the-phenolic-fraction-of-extra-virgin-olive-oil-modulates-the-activation-and-the-inflammatory-response-of-t-cells-from-patients-with-systemic-lupus-erythematosus-and-healthy-donors
#3
Marina Aparicio-Soto, Marina Sanchez-Hidalgo, Ana Cárdeno Galván, Jose Manuel Lucena, Francisca Gonzalez-Escribano, Maria Jesus Castillo Palma, Catalina Alarcón-de-la-Lastra
SCOPE: Systemic lupus erythematosus (SLE) is a chronic multiorgan autoimmune disease characterized by immune deregulation, which involves altered T-cell response and imbalance of cytokine production. The phenolic fraction (PE) of extra virgin olive oil (EVOO) possesses anti-inflammatory and immunomodulatory properties and exerts preventive effects in murine models of immune-inflammatory diseases, such as SLE. The present study was designed to determine the in vitro effects of the PE from EVOO on peripheral blood mononuclear cells (PBMC) from inactive patients with SLE and healthy donors...
February 15, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28194619/how-herbivore-browsing-strategy-affects-whole-plant-photosynthetic-capacity
#4
E Penelope Holland, Julie Mugford, Rachelle N Binny, Alex James
If a browse damage index indicates that a tree has been 50% browsed by herbivores, does this mean half the leaves are entirely eaten or are all the leaves half eaten? Were the affected leaves old or young? Large or small? In sunshine or shade? Understanding what effect browsing will have on the photosynthetic capacity and the plant's survival ability clearly requires a greater understanding of browsing strategy across the canopy than can be given by a single index value. We developed stochastic models of leaf production, growth and consumption using data from kamahi (Weinmannia racemosa) trees in New Zealand which have been browsed by possums (Trichosurus vulpecula), to ascertain which of six feasible browsing strategies possums are most likely to be employing...
February 13, 2017: Bulletin of Mathematical Biology
https://www.readbyqxmd.com/read/28193797/mediterranean-diet-improves-high-density-lipoprotein-function-in-high-cardiovascular-risk-individuals-a-randomized-controlled-trial
#5
Álvaro Hernáez, Olga Castañer, Roberto Elosua, Xavier Pintó, Ramón Estruch, Jordi Salas-Salvadó, Dolores Corella, Fernando Arós, Lluis Serra-Majem, Miquel Fiol, Manuel Ortega-Calvo, Emilio Ros, Miguel Ángel Martínez-González, Rafael de la Torre, M Carmen López-Sabater, Montserrat Fitó
BACKGROUND: The biological functions of high-density lipoproteins (HDLs) contribute to explaining the cardioprotective role of the lipoprotein beyond quantitative HDL cholesterol levels. A few small-scale interventions with a single antioxidant have improved some HDL functions. However, to date, no long-term, large-scale, randomized controlled trial has been conducted to assess the effects of an antioxidant-rich dietary pattern (such as a traditional Mediterranean diet [TMD]) on HDL function in humans...
February 14, 2017: Circulation
https://www.readbyqxmd.com/read/28190357/microdialysis-as-new-technique-for-extracting-phenolic-compounds-from-extra-virgin-olive-oil
#6
Gianfranco Bazzu, Maria Giovanna Molinu, Antonio Dore, Pier Andrea Serra
A time-consuming sample preparation is needed for obtaining the "phenolic profile" of extra virgin olive oil (EVOO). In this study, a microdialysis extraction (MDE) of polyphenols from EVOO is presented. Microdialysis probe construction and dialysis procedures were developed to maximize MDE performance and minimize the differences of polyphenol content in comparison to liquid/liquid extraction (LLE) method. "Dynamic-oil" microdialysis were performed using an extracting solution (MetOH:H2O 80:20) flow rate of 2 μl/min and a constant EVOO stream of 4 μl/min...
February 13, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28181227/independent-cytoplasmic-incompatibility-induced-by-cardinium-and-wolbachia-maintains-endosymbiont-co-infections-in-haplodiploid-thrips-populations
#7
Duong T Nguyen, Jennifer L Morrow, Robert N Spooner-Hart, Markus Riegler
Cardinium and Wolbachia are common maternally inherited reproductive parasites that can co-infect arthropods, yet interactions between both bacterial endosymbionts are rarely studied. For the first time, we report their independent expression of complete cytoplasmic incompatibility (CI) in a co-infected host, and CI in a species of the haplodiploid insect order Thysanoptera. In Pezothrips kellyanus, Cardinium-induced CI resulted in a combination of male development (MD) and embryonic female mortality (FM) of fertilised eggs...
February 9, 2017: Evolution; International Journal of Organic Evolution
https://www.readbyqxmd.com/read/28179491/increases-in-plasma-tryptophan-are-inversely-associated-with-incident-cardiovascular-disease-in-the-prevenci%C3%A3-n-con-dieta-mediterr%C3%A3-nea-predimed-study
#8
Edward Yu, Miguel Ruiz-Canela, Marta Guasch-Ferré, Yan Zheng, Estefania Toledo, Clary B Clish, Jordi Salas-Salvadó, Liming Liang, Dong D Wang, Dolores Corella, Montse Fitó, Enrique Gómez-Gracia, José Lapetra, Ramón Estruch, Emilio Ros, Montserrat Cofán, Fernando Arós, Dora Romaguera, Lluis Serra-Majem, Jose V Sorlí, Frank B Hu, Miguel A Martinez-Gonzalez
Background: During development of cardiovascular disease (CVD), interferon-γ-mediated inflammation accelerates degradation of tryptophan into downstream metabolites. A Mediterranean diet (MedDiet) consisting of a high intake of extra-virgin olive oil (EVOO), nuts, fruits, vegetables, and cereals has been demonstrated to lower the risk of CVD. The longitudinal relation between tryptophan and its downstream metabolites and CVD in the context of a MedDiet is unstudied.Objective: We sought to investigate the relation between metabolites in the tryptophan-kynurenine pathway and CVD in the context of a MedDiet pattern...
February 8, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28178203/male-psyllids-differentially-learn-in-the-context-of-copulation
#9
Dara G Stockton, Xavier Martini, Lukasz L Stelinski
In the Asian citrus psyllid, Diaphorina citri Kuwayama, stimulatory cuticular hydrocarbons act as sex pheromone attractants. Male psyllids locate aggregations of females using those olfactory cues, as well as vibrational communication on the plant surface. Although previous research has indicated that learning plays a role in modulating female reproductive behaviors in psyllids, it is unknown whether males similarly use learning to increase the likelihood of copulatory success. We used an olfactometer-based bio-assay to study the effects of experience on male response to female odor...
February 7, 2017: Insects
https://www.readbyqxmd.com/read/28168411/potential-therapeutic-role-of-punicalagin-against-mechanical-trauma-induced-stress-urinary-incontinence-via-upregulation-of-nrf2-and-tgf-%C3%AE-1-signaling-effect-of-punicalagin-on-mechanical-trauma-induced-sui
#10
Jianming Tang, Cheng Liu, Jie Min, Ming Hu, Yang Li, Li Hong
INTRODUCTION AND HYPOTHESIS: We investigated the effect of punicalagin (PUN; 2,3-hexahydroxydiphenoyl-gallagyl-D-glucose), on mechanical-trauma-induced stress urinary incontinence (SUI) in mouse and the mechanisms underlying any effects. METHODS: Ninety virgin female C57BL/6 mice were randomized into six groups: five groups underwent vaginal distention (VD) for 1 h and leak-point pressure (LPP) was measured on the 1st, 3rd, 7th, 14th, and 28th day following (VD groups 1 d, 3 d, 7 d, 14 d, and 28 d)...
February 6, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28168252/antiscaling-efficacy-of-caco3-and-caso4-on-polyethylene-glycol-peg-modified-reverse-osmosis-membranes-in-the-presence-of-humic-acid-interplay-of-membrane-surface-properties-and-water-chemistry
#11
Jessica R Ray, Whitney Wong, Young-Shin Jun
Mineral scaling persists in many water treatment processes. More specifically, it can significantly reduce the efficacy of aromatic polyamide (PA) membranes during reverse osmosis (RO) water treatment. Previous studies have integrated hydrophilic materials, such as polyethylene glycol (PEG), onto RO membranes to combat scaling from generally hydrophobic feed water constituents; however, there are still outstanding knowledge gaps regarding the interplay of the modified membrane surface chemistry and the water chemistry in complex RO feed waters...
February 7, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28161002/-quiz-ready-study-score
#12
Hélène Roussel, Laure Gibault, Virgine Verkarre, Sylvie Lantuejoul, Cécile Badoual
No abstract text is available yet for this article.
February 1, 2017: Annales de Pathologie
https://www.readbyqxmd.com/read/28159296/autochthonous-cultivars-of-emilia-romagna-region-and-their-clones-comparison-of-the-chemical-and-sensory-properties-of-olive-oils
#13
Annalisa Rotondi, Chiara Lapucci, Lucia Morrone, Luisa Neri
The olive species (Olea europaea L.) is characterized by significant phenotypic and genetic variability the genetic matrix has a strong influence on several important extra virgin olive oil (EVOO) chemical components. Four clones from cultivars autochthonous of the Emilia Romagna region were selected for their notable performance in terms of agronomical characteristics, and the quality of the olive oil produced was studied in detail. In particular, we analyzed the fatty acid composition, the phenolic profile and the sensory analysis of the oils from these clones and compared them with the oils from the respective cultivars...
June 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28153311/multiple-internal-standard-normalization-for-improving-hs-spme-gc-ms-quantitation-in-virgin-olive-oil-volatile-organic-compounds-voo-vocs-profile
#14
Martina Fortini, Marzia Migliorini, Chiara Cherubini, Lorenzo Cecchi, Luca Calamai
The commercial value of virgin olive oils (VOOs) strongly depends on their classification, also based on the aroma of the oils, usually evaluated by a panel test. Nowadays, a reliable analytical method is still needed to evaluate the volatile organic compounds (VOCs) and support the standard panel test method. To date, the use of HS-SPME sampling coupled to GC-MS is generally accepted for the analysis of VOCs in VOOs. However, VOO is a challenging matrix due to the simultaneous presence of: i) compounds at ppm and ppb concentrations; ii) molecules belonging to different chemical classes and iii) analytes with a wide range of molecular mass...
April 1, 2017: Talanta
https://www.readbyqxmd.com/read/28153304/in-pipette-solid-phase-extraction-prior-to-flow-modulation-comprehensive-two-dimensional-gas-chromatography-with-dual-detection-for-the-determination-of-minor-components-in-vegetable-oils
#15
Laura Barp, Flavio A Franchina, Giorgia Purcaro, Peter Q Tranchida, Luigi Mondello
The present research is based on the development of an effective, environmentally-friendly and low-cost method for investigation of minor components in vegetable oils, exploiting the advantages of a miniaturized solid-phase extraction (SPE) and the potential of flow modulation (FM) comprehensive two-dimensional gas chromatography (GC×GC), coupled to a mass spectrometer (MS) and a flame ionization detector (FID). The initial sample preparation step was carried out using a miniaturized approach characterized by a SPE process in a Pasteur pipette...
April 1, 2017: Talanta
https://www.readbyqxmd.com/read/28149499/bariatric-surgery-emphasizes-biological-sex-differences-in-rodent-hepatic-lipid-handling
#16
Bernadette E Grayson, Ruth Gutierrez-Aguilar, Joyce E Sorrell, Emily K Matter, Michelle R Adams, Philip Howles, Rebekah Karns, Randy J Seeley, Darleen A Sandoval
BACKGROUND: Eighty percent of patients who receive bariatric surgery are women, yet the majority of preclinical studies are in male rodents. Because sex differences drive hepatic gene expression and overall lipid metabolism, we sought to determine whether sex differences were also apparent in these endpoints in response to bariatric surgery. METHODS: Two cohorts of age-matched virgin male and female Long-Evans rats were placed on a high fat diet for 3 weeks and then received either Sham or vertical sleeve gastrectomy (VSG), a surgery which resects 80% of the stomach with no intestinal rearrangement...
2017: Biology of Sex Differences
https://www.readbyqxmd.com/read/28148219/upregulation-of-juvenile-hormone-titers-in-female-drosophila-melanogaster-through-mating-experiences-and-host-food-occupied-by-eggs-and-larvae
#17
Yasuhiro Sugime, Dai Watanabe, Yoko Yasuno, Tetsuro Shinada, Toru Miura, Nobuaki K Tanaka
Juvenile hormone (JH) plays a crucial role in the determination of developmental timing in insects. In Drosophila melanogaster, reports indicate that JH titers are the highest immediately following eclosion and that the mating experience increases the titers in females. However, the titers have not been successively measured for an extended period of time after eclosion. This study reveals that JH titers are increased after eclosion in virgin females when supplied with food that is occupied by eggs and larvae as well as in mated females...
February 2017: Zoological Science
https://www.readbyqxmd.com/read/28145404/ethological-principles-predict-the-neuropeptides-co-opted-to-influence-parenting
#18
Christopher B Cunningham, Majors J Badgett, Richard B Meagher, Ron Orlando, Allen J Moore
Ethologists predicted that parental care evolves by modifying behavioural precursors in the asocial ancestor. As a corollary, we predict that the evolved mechanistic changes reside in genetic pathways underlying these traits. Here we test our hypothesis in female burying beetles, Nicrophorus vespilloides, an insect where caring adults regurgitate food to begging, dependent offspring. We quantify neuropeptide abundance in brains collected from three behavioural states: solitary virgins, individuals actively parenting or post-parenting solitary adults and quantify 133 peptides belonging to 18 neuropeptides...
February 1, 2017: Nature Communications
https://www.readbyqxmd.com/read/28143667/extra-virgin-olive-oil-consumption-reduces-the-risk-of-osteoporotic-fractures-in-the-predimed-trial
#19
J F García-Gavilán, M Bulló, S Canudas, M A Martínez-González, R Estruch, S Giardina, M Fitó, D Corella, E Ros, J Salas-Salvadó
BACKGROUND & AIMS: The incidence of osteoporotic fractures is lower in countries in the Mediterranean basin. Virgin olive oil, a key component of the Mediterranean Diet (MDiet), with recognised beneficial effects on metabolism and cardiovascular health, may decrease the risk of osteoporotic fractures. The aim to this study was to explore the effect of chronic consumption of total olive oil and its varieties on the risk of osteoporosis-related fractures in a middle-aged and elderly Mediterranean population...
January 13, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28143632/extracellular-like-matrices-and-leukaemia-inhibitory-factor-for-in-vitro-culture-of-human-primordial-follicles
#20
Assiel J Younis, Galit Lerer-Serfaty, Dana Stav, Bethsabee Sabbah, Tzippy Shochat, Gania Kessler-Icekson, Muayad A Zahalka, Michal Shachar-Goldenberg, Avi Ben-Haroush, Benjamin Fisch, Ronit Abir
The possibility of maturing human primordial follicles in vitro would assist fertility restoration without the danger of reseeding malignancies. Leukaemia inhibitory factor (LIF) and certain culture matrices may promote human follicular growth. The present study compared human primordial follicular growth on novel culture matrices, namely human recombinant vitronectin (hrVit), small intestine submucosa (SIS), alginate scaffolds and human recombinant virgin collagen bioengineered in tobacco plant lines (CollPlant)...
February 1, 2017: Reproduction, Fertility, and Development
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