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sleep apnea in renal failure

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https://www.readbyqxmd.com/read/27886849/prevalence-and-burden-of-comorbidities-in-chronic-obstructive-pulmonary-disease
#1
REVIEW
Alexandru Corlateanu, Serghei Covantev, Alexander G Mathioudakis, Victor Botnaru, Nikolaos Siafakas
The classical definition of Chronic Obstructive Pulmonary Disease (COPD) as a lung condition characterized by irreversible airway obstruction is outdated. The systemic involvement in patients with COPD, as well as the interactions between COPD and its comorbidities, justify the description of chronic systemic inflammatory syndrome. The pathogenesis of COPD is closely linked with aging, as well as with cardiovascular, endocrine, musculoskeletal, renal, and gastrointestinal pathologies, decreasing the quality of life of patients with COPD and, furthermore, complicating the management of the disease...
November 2016: Respiratory Investigation
https://www.readbyqxmd.com/read/27766526/implementation-of-a-novel-postoperative-monitoring-system-using-automated-modified-early-warning-scores-mews-incorporating-end-tidal-capnography
#2
Joseph M Blankush, Robbie Freeman, Joy McIlvaine, Trung Tran, Stephen Nassani, I Michael Leitman
Modified Early Warning Scores (MEWS) provide real-time vital sign (VS) trending and reduce ICU admissions in post-operative patients. These early warning calculations classically incorporate oxygen saturation, heart rate, respiratory rate, systolic blood pressure, and temperature but have not previously included end-tidal CO2 (EtCO2), more recently identified as an independent predictor of critical illness. These systems may be subject to failure when physiologic data is incorrectly measured, leading to false alarms and increased workload...
October 20, 2016: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/27547150/right-ventricular-enlargement-within-months-of-arteriovenous-fistula-creation-in-2-hemodialysis-patients
#3
Loheetha Ragupathi, Drew Johnson, Gregary D Marhefka
Surgically created arteriovenous fistulae (AVF) for hemodialysis can contribute to hemodynamic changes. We describe the cases of 2 male patients in whom new right ventricular enlargement developed after an AVF was created for hemodialysis. Patient 1 sustained high-output heart failure solely attributable to the AVF. After AVF banding and subsequent ligation, his heart failure and right ventricular enlargement resolved. In Patient 2, the AVF contributed to new-onset right ventricular enlargement, heart failure, and ascites...
August 2016: Texas Heart Institute Journal
https://www.readbyqxmd.com/read/27508727/-op-4d-08-disordered-sleep-breathing-sdb-is-the-major-determinant-of-non-dipping-and-nocturnal-hypertension-in-kidney-transplant-patients
#4
F Mallamaci, R Tripepi, M C Versace, F Provenzano, A Mafrica, C Torino, G D'Arrigo, D Leonardis, G Tripepi, C Zoccali
OBJECTIVE: In renal transplant patients, the prevalence of nocturnal hypertension by far exceeds that of hypertension as assessed by clinic, daytime, and average 24-hour ABPM and night-time systolic BP (SBP) and the night-day ratio but no other BP metrics are independently associated with IMT in this population (Transplantation 2015 Dec 17). BP during nighttime may provide information for the assessment of CV risk attributable to BP burden in renal transplant patients but the determinants of this phenomenon are still undefined in these patients...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27191365/chronic-kidney-disease-in-european-patients-with-obstructive-sleep-apnea-the-esada-cohort-study
#5
Oreste Marrone, Salvatore Battaglia, Paschalis Steiropoulos, Ozen K Basoglu, John A Kvamme, Silke Ryan, Jean-Louis Pepin, Johan Verbraecken, Ludger Grote, Jan Hedner, Maria R Bonsignore
The cross-sectional relationship of obstructive sleep apnea with moderate to severe chronic kidney disease, defined as an estimated glomerular filtration rate <60 mL min(-1) ∙1.73 m(-2) , was investigated in a large cohort of patients with suspected obstructive sleep apnea studied by nocturnal polysomnography or cardiorespiratory polygraphy. Data were obtained from the European Sleep Apnea Database, where information from unselected adult patients with suspected obstructive sleep apnea afferent to 26 European sleep centres had been prospectively collected...
May 18, 2016: Journal of Sleep Research
https://www.readbyqxmd.com/read/26815045/a-systematic-review-of-central-sleep-apnea-in-adult-patients-with-chronic-kidney-disease
#6
Gaurav Nigam, Charu Pathak, Muhammad Riaz
BACKGROUND: Obstructive sleep apnea has been widely studied in patients with chronic renal insufficiency; however only a limited number of studies have reviewed the association between central sleep apnea (CSA) and chronic kidney disease (CKD). The objectives of this systematic review were to assess the prevalence of CSA in and its association with CKD in adult patients and to determine if inclusion of the central hypopnea index affected the reported rates for the prevalence of CSA in CKD...
September 2016: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/26781253/central-sympathetic-inhibition-a-neglected-approach-for-treatment-of-cardiac-arrhythmias
#7
REVIEW
Francesca Cagnoni, Maurizio Destro, Erika Bontempelli, Giovanni Locatelli, Dagmara Hering, Markus P Schlaich
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. Overactivation of the sympathetic nervous system (SNS) plays an important role in the pathogenesis of comorbidities related to AF such as hypertension, congestive heart failure, obesity, insulin resistance, and obstructive sleep apnea. Methods that reduce sympathetic drive, such as centrally acting sympatho-inhibitory agents, have been shown to reduce the incidence of spontaneous or induced atrial arrhythmias, suggesting that neuromodulation may be helpful in controlling AF...
February 2016: Current Hypertension Reports
https://www.readbyqxmd.com/read/26765143/intradialytic-hypoxemia-in-chronic-hemodialysis-patients
#8
Israel Campos, Lili Chan, Hanjie Zhang, Sheila Deziel, Cheryl Vaughn, Anna Meyring-Wösten, Peter Kotanko
When kidney failure occurs, patients are at risk for fluid overload states, which can cause pulmonary edema, pleural effusions, and upper airway obstruction. Kidney disease is also associated with impaired respiratory function, as in central sleep apnea or chronic obstructive pulmonary disease. Hence, respiratory and renal diseases are frequently coexisting. Hypoxemia is the terminal pathway of a multitude of respiratory pathologies. The measurement of oxygen saturation (SO2) is a basic and commonly used tool in clinical practice...
2016: Blood Purification
https://www.readbyqxmd.com/read/26737658/modeling-sleep-apnea-severity-using-bioimpedance-measurements
#9
Bojan Gavrilovic, Milos R Popovic, Azadeh Yadollahi
Obstructive sleep apnea (OSA) is a common disorder in adults characterized by repetitive collapse of the pharynx. OSA prevalence increases in fluid retaining patients such as those with heart or renal failure, and worsens with overnight fluid accumulation in the neck. The objective of this study was to develop a new method of measuring changes in intracellular water (ICW) in the neck, and investigate metrics that represent total neck impedance and their relationship to sleep apnea severity. In 18 non-obese men, neck fluid volume (NFV) was measured before and after sleep using bioelectrical impedance at 50 kHz...
2015: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/26664564/risk-of-obstructive-sleep-apnea-among-saudis-with-chronic-renal-failure-on-hemodialysis
#10
Siraj Omar Wali, Abeer Alkhouli, Mohannad Howladar, Ibrahim Ahmad, Saad Alshohaib, Saeed Al-Ghamdi, Ayman Krayem
AIM: The prevalence of obstructive sleep apnea (OSA) in end-stage renal disease (ESRD) patients was reported to be 10-fold that in the general population. OSA can worsen the clinical symptoms and cardiovascular complications of ESRD. We aimed to investigate the prevalence of symptoms and risk of OSA among Saudi patients with ESRD. SETTINGS AND DESIGN: This multi-center, cross-sectional study was conducted in Jeddah, Saudi Arabia, between June 2012 and September 2013...
October 2015: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/26491559/implications-of-renal-denervation-therapy-in-patients-with-sleep-apnea
#11
REVIEW
Fernando Jaén-Águila, José Antonio Vargas-Hitos, Juan Diego Mediavilla-García
Obstructive sleep apnea (OSA) syndrome is a prevalent condition characterized by repeated episodes of obstruction of the upper airway, leading to intermittent hypoxemia and important endothelial and anatomical dysfunctions that cause cardiovascular and cerebrovascular disease. The finding of the relationship between OSA and hypertension, especially resistant hypertension (RHT), has increased the interest in therapeutic strategies that affect renal sympathetic activity in these patients. The observational studies published until now demonstrated that renal denervation therapy can reduce the severity of OSA syndrome...
2015: International Journal of Hypertension
https://www.readbyqxmd.com/read/26355255/hypervolemia-and-sleep-apnea-in-kidney-disease
#12
REVIEW
Owen D Lyons, T Douglas Bradley, Christopher T Chan
In end-stage renal disease (ESRD) and heart failure, conditions characterized by fluid overload, both obstructive sleep apnea (OSA) and central sleep apnea (CSA) are highly prevalent. This observation suggests that fluid overload may be a unifying mechanism in the pathogenesis of both OSA and CSA in these conditions. An overnight rostral fluid shift from the legs to the neck and lungs has been shown to contribute to the pathogenesis of OSA and CSA, respectively, in various different patient populations. This article reviews the evidence that supports a role for fluid overload and overnight fluid shift in the pathogenesis of sleep apnea in ESRD...
July 2015: Seminars in Nephrology
https://www.readbyqxmd.com/read/26355252/central-sleep-apnea-in-kidney-disease
#13
REVIEW
Sushma M Dharia, Mark L Unruh, Lee K Brown
Sleep is an essential function of life and serves a crucial role in the promotion of health and performance. Poor sleep quality and sleep disorders have been a recurrent finding in patients with chronic kidney disease (CKD). Sleep disorders such as obstructive sleep apnea (OSA) can contribute to hypertension, diabetes, cardiovascular disease, and worsen obesity, all of which are implicated in the etiology of CKD, but CKD itself may lead to OSA. Relationships between CKD/end-stage renal disease (ESRD) and OSA have been the subject of numerous investigations, but central sleep apnea (CSA) also is highly prevalent in CKD/ESRD but remains poorly understood, underdiagnosed, and undertreated in these patients...
July 2015: Seminars in Nephrology
https://www.readbyqxmd.com/read/26235653/sleep-apnea-is-associated-with-new-onset-atrial-fibrillation-after-coronary-artery-bypass-grafting
#14
Liang-Ping Zhao, Theodoros Kofidis, Toon-Wei Lim, Siew-Pang Chan, Thun-How Ong, Huay-Cheem Tan, Chi-Hang Lee
PURPOSE: New-onset atrial fibrillation (AF) after coronary artery bypass grafting (CABG) remains a prevalent problem. We investigated the relationship between sleep apnea and new-onset post-CABG AF during inhospital stay. MATERIALS AND METHODS: We prospectively recruited 171 patients listed for an elective CABG for an overnight sleep study. Sleep apnea was defined as apnea-hypopnea index greater than or equal to 5. RESULTS: Among the 160 patients who completed the study, those in the sleep apnea group (n=128; 80%) had larger left atrial diameter (40...
December 2015: Journal of Critical Care
https://www.readbyqxmd.com/read/26117480/leptin-level-correlates-with-obesity-and-health-related-quality-of-life-in-obstructive-sleep-apnea-syndrome-patients
#15
Abhishek Dubey, Surya Kant, Sunita Tiwari, Sarita Agarwal, Abbas Ali Mahdi
BACKGROUND: Leptin takes part in regulation of energy balance, neuronal functions, pain and mood. It may act as intermediary marker for various components of HRQOL in patients of obstructive sleep apnea syndrome. AIMS: To document the correlation among leptin levels, obesity and HRQoL in OSAS patients. METHODS: A tertiary care hospital based cross-sectional study was done in 224 subjects aged 18-65 years, after taking informed consent. Subjects with previous history of smoking, Liver disease, COPD, CHD, T2 DM, asthma, cancer, end stage renal disease, heart failure, any endocrine disorder including Cushing syndrome, thyroid, on systemic steroid or any continuous medication for last 6 months, on dieting or suffering from any disability condition (other than obesity and OSAS) affecting their HRQoL were excluded from the study...
April 2015: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/25940851/the-relationship-between-volume-overload-in-end-stage-renal-disease-and-obstructive-sleep-apnea
#16
Maria-Eleni Roumelioti, Lee K Brown, Mark L Unruh
Obstructive sleep apnea (OSA) is common, underdiagnosed, and undertreated among patients with end-stage renal disease (ESRD). As in all cases, pathogenesis of OSA is related to repeated upper airway (UA) occlusion or narrowing, but in ESRD, additional contributory factors likely include uremic destabilization of central respiratory control and anatomic changes in the UA related to fluid status. Pulmonary congestion is common in acute and chronic kidney failure and is a consequence of cardiomyopathy and fluid overload, two potentially reversible risk factors...
September 2015: Seminars in Dialysis
https://www.readbyqxmd.com/read/25787734/drug-therapy-of-apparent-treatment-resistant-hypertension-focus-on-mineralocorticoid-receptor-antagonists
#17
REVIEW
Daniel Glicklich, William H Frishman
Apparent treatment-resistant hypertension (aTRH) is defined as blood pressure (BP) >140/90 mmHg despite three different antihypertensive drugs including a diuretic. aTRH is associated with an increased risk of cardiovascular events, including stroke, chronic renal failure, myocardial infarction, congestive heart failure, aortic aneurysm, atrial fibrillation, and sudden death. Preliminary studies of renal nerve ablation as a therapy to control aTRH were encouraging. However, these results were not confirmed by the Symplicity 3 trial...
April 2015: Drugs
https://www.readbyqxmd.com/read/25716960/saliva-and-oxidative-stress-in-oral-cavity-and-in-some-systemic-disorders
#18
REVIEW
P Buczko, A Zalewska, I Szarmach
Saliva is a liquid environment of the oral ecosystem that to some extent reflects the local state of oral cavity or the general state of health of the human body. Since saliva reflects general health status of the human organism and is easy to collect, it can be used as a non-invasive diagnostic tool. In the present review the authors discuss and highlight the role of oxidant-antioxidant balance in the blood and saliva in human pathology. Particularly, the evaluation of oxidative stress status was proposed as an important factor in diagnosing the development and progress of such general diseases as periodontal disease, oral cancer, diabetes, rheumatoid arthritis, chronic renal failure, obstructive sleep apnea syndrome, and HIV...
February 2015: Journal of Physiology and Pharmacology: An Official Journal of the Polish Physiological Society
https://www.readbyqxmd.com/read/25711520/the-first-polish-liver-transplantation-after-roux-en-y-gastric-bypass-surgery-for-morbid-obesity-a-case-report-and-literature-review
#19
REVIEW
Rafał Marszałek, Paweł Ziemiański, Beata Łągiewska, Marek Pacholczyk, Justyna Domienik-Karłowicz, Janusz Trzebicki, Zbigniew Wierzbicki, Krzysztof Jankowski, Maciej Kosieradzki, Dariusz Wasiak, Maurycy Jonas, Piotr Pruszczyk, Magdalena Durlik, Wojciech Lisik, Andrzej Chmura
BACKGROUND: Morbid obesity is associated with liver pathology, most commonly non-alcoholic steatohepatitis (NASH) leading to cirrhosis. However, the morbid obesity impedes qualification for organ transplantation. CASE REPORT: We present a case report of a 56-year-old woman who underwent bariatric procedure followed by liver transplantation (LTx). Her initial weight was 130.2 kg (BMI 50.9 kg/m2). The patient had a history of arterial hypertension, diabetes, gonarthrosis, and obstructive sleep apnea syndrome and no history of alcohol abuse...
2015: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/25700646/-rare-forms-of-hypertension-from-pheochromocytoma-to-vasculitis
#20
H Haller, F Limbourg, B M Schmidt, J Menne
Secondary hypertension affects only 5-10 % of hypertensive patients. Screening is expensive and time-consuming and should be performed only in patients for whom there is a high clinical suspicion of secondary hypertension. Clinical signs of secondary forms of hypertension are new-onset hypertension in patients without other risk factors (i.e., family history, obesity, etc.), sudden increase of blood pressure (BP) in a previously stable patient, increased BP in prepubertal children, resistant hypertension, and severe hypertension or hypertensive emergencies...
March 2015: Der Internist
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