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https://www.readbyqxmd.com/read/27905610/dendritic-polyglycerol-and-n-isopropylacrylamide-based-thermoresponsive-nanogels-as-smart-carriers-for-controlled-delivery-of-drugs-through-the-hair-follicle
#1
Fitsum Feleke Sahle, Michael Giulbudagian, Julian Bergueiro, Jürgen Lademann, Marcelo Calderón
Nanoparticles with a size of several hundred nanometers can effectively penetrate into the hair follicles and may serve as depots for controlled drug delivery. However, they can neither overcome the hair follicle barrier to reach the viable cells nor release the loaded drug adequately. On the other hand, small drug molecules cannot penetrate deep into the hair follicles. Thus, the most efficient way for drug delivery through the follicular route is to employ nanoparticles that can release the drug close to the target structure upon exposure to some external or internal stimuli...
December 1, 2016: Nanoscale
https://www.readbyqxmd.com/read/27896487/natural-compounds-as-occult-ototoxins-ginkgo-biloba-flavonoids-moderately-damage-lateral-line-hair-cells
#2
Sarah Neveux, Nicole K Smith, Anna Roche, Bruce E Blough, Wimal Pathmasiri, Allison B Coffin
Several drugs, including aminoglycosides and platinum-based chemotherapy agents, are well known for their ototoxic properties. However, FDA-approved drugs are not routinely tested for ototoxicity, so their potential to affect hearing often goes unrecognized. This issue is further compounded for natural products, where there is a lack of FDA oversight and the manufacturer is solely responsible for ensuring the safety of their products. Natural products such as herbal supplements are easily accessible and commonly used in the practice of traditional eastern and alternative medicine...
November 28, 2016: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/27872999/laccase-catalysis-for-the-synthesis-of-bioactive-compounds
#3
REVIEW
Tukayi Kudanga, Blessing Nemadziva, Marilize Le Roes-Hill
The demand for compounds of therapeutic value is increasing mainly because of new applications of bioactive compounds in medicine, pharmaceutical, agricultural, and food industries. This has necessitated the search for cost-effective methods for producing bioactive compounds and therefore the intensification of the search for enzymatic approaches in organic synthesis. Laccase is one of the enzymes that have shown encouraging potential as biocatalysts in the synthesis of bioactive compounds. Laccases are multicopper oxidases with a diverse range of catalytic activities revolving around synthesis and degradative reactions...
November 21, 2016: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/27826822/an-updated-systematic-review-on-the-possible-effect-of-nonylphenol-on-male-fertility
#4
Zahra Noorimotlagh, Neemat Jaafarzadeh Haghighi, Mehdi Ahmadimoghadam, Fakher Rahim
Diverse industries like detergents, resins and polymers, hair dyes, intravaginal spermicides, and pesticides produce endocrine disruptor (ED)-containing wastewaters that have hazardous effects on the environment and public health. Nonylphenol (NP) is a chemical substance that consists of a phenolic group and an attached lipophilic linear nonyl chain. NP has weak estrogenic activity and affects estrogen receptor (ER), as well as induces male infertility via a negative impact on spermatogenesis and sperm quality...
November 8, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27792983/feather-keratin-hydrogel-for-wound-repair-preparation-healing-effect-and-biocompatibility-evaluation
#5
Ju Wang, Shilei Hao, Tiantian Luo, Zhongjun Cheng, Wenfeng Li, Feiyan Gao, Tingwang Guo, Yuhua Gong, Bochu Wang
Keratins are highly attractive for wound healing due to their inherent bioactivity, biocompatibility and physical properties. However, nearly all wound healing studies have focused on human hair keratins, and the wound-repair effects and in vivo biocompatibilities of feather keratins are not clear. Feather keratins are derived from chicken feathers, which are considered to be the major waste in the poultry industry, and the quality of feather keratin is easier to control than that of human hair keratin due to human hair perming and colouring-dyeing...
October 22, 2016: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/27775972/tolerance-to-a-hair-dye-product-containing-2-methoxymethyl-p-phenylenediamine-in-an-ethnically-diverse-population-of-p-phenylenediamine-allergic-individuals
#6
Amir Zahir, Chesahna Kindred, Brunhilde Blömeke, Carsten Goebel, Anthony A Gaspari
BACKGROUND: Allergic contact dermatitis after exposure to p-phenylenediamine (PPD)-containing hair dye products is a common and important clinical problem. Because there is a high rate of cross-elicitation of allergic contact dermatitis to other important hair dye products (such as p-toluene diamine and other aminophenol hair dyes) in PPD-allergic patients, safer alternative dyes with excellent hair coloring options are needed. OBJECTIVE: This study aimed to study tolerance to Me-PPD in a PPD-allergic cohort...
October 21, 2016: Dermatitis
https://www.readbyqxmd.com/read/27762642/efficacy-and-safety-of-mascara-dyeing-as-an-adjunct-to-alexandrite-and-nd-yag-laser-applications-for-removing-thin-and-white-colored-facial-and-axillary-hair
#7
Pelin Üstüner, Ali Balevi, Mustafa Özdemir
INTRODUCTION: There is no satisfactory and efficient method for long-term removal of white-colored and thin hair. METHODS: We conducted a randomised clinical trial of hirsute patients with excessive white and/or thin hair on the face and/or axilla. In Group I (n: 16), the facial hair on one side of the face was painted with a black eyelash mascara immediately before Nd:YAG laser and the other half was only treated by Nd:YAG. In Group II (n: 20), the axillary hair on one side was painted with the mascara before the Alexandrite laser with the other side being only treated by Alexandrite...
October 20, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27749802/severe-neck-and-face-edema-in-an-adolescent-delayed-hypersensitivity-reaction-to-hair-dye
#8
Sakine Işik, Sule Caglayan-Sözmen, Özden Anal, Özkan Karaman, Nevin Uzuner
Allergic contact reactions to hair dyes arise mostly due to sensitization to para-phenylenediamine (PPD). Para-phenylenediamine, a derivative of p-nitroanaline, is widely used as an oxydizable hair dye and is also found in black henna tattoo. Subsequent exposure to PPD may lead to delayed type IV hypersensitivity reaction manifesting as acute contact dermatitis. Here, a 15-year-old girl is presented, who developed a hypersensitivity reaction after first exposure to hair dye. She was found to have been sensitized to PPD before, through application of black henna tatto...
October 4, 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27728598/myocarditis-in-hair-dye-poisoning
#9
K Sivarama Krishna
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27693856/gradient-dependent-release-of-the-model-drug-tritc-dextran-from-fitc-labeled-bsa-hydrogel-nanocarriers-in-the-hair-follicles-of-porcine-ear-skin
#10
Ngo Bich Nga Nathalie Tran, Fanny Knorr, Wing Cheung Mak, Kwan Yee Cheung, Heike Richter, Martina Meinke, Jürgen Lademann, Alexa Patzelt
Hair follicle research is currently focused on the development of drug-loaded nanocarriers for the targeting of follicular structures in the treatment of skin and hair follicle-related disorders. In the present study, a dual-label nanocarrier system was implemented in which FITC-labeled BSA hydrogel nanocarriers loaded with the model drug and dye TRITC-dextran were applied topically to porcine ear skin. Follicular penetration and the distribution of both dyes corresponding to the nanocarriers and the model drug in the follicular ducts subsequent to administration to the skin were investigated using confocal laser scanning microscopy...
September 29, 2016: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/27688442/dermatoses-among-children-from-celebration-of-holi-the-spring-festival-in-india-a-cross-sectional-observational-study
#11
Sudip Kumar Ghosh, Debabrata Bandyopadhyay, Megha Agarwal, Olympia Rudra
BACKGROUND: "Holi" is a spring festival celebrated primarily in the Indian subcontinent and also abroad by expatriate Indians. It is a festival of colors, traditionally celebrated by mutual application of colors in different forms on a particular day of the year. These colors frequently comprise a range of synthetic dyes which have harmful effects on the skin and mucosae. Children take part in this colorful festival with much enthusiasm and vigor, making them prone to develop different "Holi"-related dermatoses...
September 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/27633650/comparative-sensitizing-potencies-of-fragrances-preservatives-and-hair-dyes
#12
Carola Lidén, Kerem Yazar, Jeanne D Johansen, Ann-Therese Karlberg, Wolfgang Uter, Ian R White
The local lymph node assay (LLNA) is used for assessing sensitizing potential in hazard identification and risk assessment for regulatory purposes. Sensitizing potency on the basis of the LLNA is categorized into extreme (EC3 value of ≤0.2%), strong (>0.2% to ≤2%), and moderate (>2%). To compare the sensitizing potencies of fragrance substances, preservatives, and hair dye substances, which are skin sensitizers that frequently come into contact with the skin of consumers and workers, LLNA results and EC3 values for 72 fragrance substances, 25 preservatives and 107 hair dye substances were obtained from two published compilations of LLNA data and opinions by the Scientific Committee on Consumer Safety and its predecessors...
November 2016: Contact Dermatitis
https://www.readbyqxmd.com/read/27620129/a-case-of-chronic-contact-dermatitis-resulting-from-the-use-of-blue-hair-dye
#13
Gary K Soffer, Jennifer Toh, Stacy Clements, Sunit Jariwala
No abstract text is available yet for this article.
October 2016: Contact Dermatitis
https://www.readbyqxmd.com/read/27608065/para-phenylenediamine-hypersensitivity-a-report-from-budapest-hungary-2007-2014
#14
Györgyi Pónyai, Brigitte Mária Diczig, Ilona Németh, Erzsébet Temesvári
BACKGROUND: para-Phenylenediamine (PPD) is a potent allergen with frequent exposure through use of hair dyes or henna tattoos. OBJECTIVES: We wished to determine if prevalence of PPD sensitivity is changing through time as trends in its use change. PATIENTS: A total of 3631 patients were patch tested consecutively with the environmental standard series between 2007 and 2014 to map the prevalence of PPD sensitivity and its distribution according to age, sex, and diagnosis...
September 2016: Dermatitis
https://www.readbyqxmd.com/read/27606555/herpes-zoster-masquerading-as-a-chemical-burn-secondary-to-hair-dye
#15
Timothy P Crowley, Susan Stevenson
Chemical burns secondary to hair dye are very rare but have been reported. Here, we present a case of herpes zoster, which was initially mistaken for a chemical burn. Herpes zoster reactivation (shingles) is common and can give rise to skin loss clinically similar to that of a burn. It is important that clinicians consider this alternative diagnosis to ensure that timely antiviral therapy is initiated so as to reduce further skin loss and future scarring.
August 18, 2016: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/27601867/scanning-electron-microscopy-study-of-hair-shaft-damage-secondary-to-cosmetic-treatments-of-the-hair
#16
Feroze Kaliyadan, B B Gosai, Walid Naief Al Melhim, Kaberi Feroze, Habib Ahmad Qureshi, Sayed Ibrahim, Joel Kuruvilla
INTRODUCTION AND BACKGROUND: Cosmetic procedures for hair, such as bleaching, dyeing, and straightening, are commonly used around the world. It has been suggested that excessive use of such procedures can cause damage to the hair shaft. We aimed to assess hair shaft changes using scanning electron microscopy (SEM) in female volunteers who frequently use hair treatment procedures such as bleaching, dyeing, or straightening. METHODS: A cross-sectional, controlled study in a sample of 25 female volunteers (19 study group and 6 controls) in the age group of 18-45 years...
April 2016: International Journal of Trichology
https://www.readbyqxmd.com/read/27593503/cosmetic-components-causing-contact-urticaria-a-review-and-update
#17
REVIEW
Lien Verhulst, An Goossens
Immediate skin reactions are common in dermatological practice, but may often be overlooked. The main objective of this article is to provide an update of the literature concerning immediate-type reactions or contact urticaria/contact urticaria syndrome caused by cosmetic ingredients in terms of immediate clinical symptoms, positive reactions following open, scratch or, most often, prick testing, and sometimes the detection of specific IgE antibodies. To this end, a selective search in different medical literature databases was performed...
December 2016: Contact Dermatitis
https://www.readbyqxmd.com/read/27591371/rapid-monitoring-of-residual-uv-stabilizers-in-seawater-samples-from-beaches-using-fabric-phase-sorptive-extraction-and-uhplc-ms-ms
#18
Romualdo B García-Guerra, Sarah Montesdeoca-Esponda, Zoraida Sosa-Ferrera, Abuzar Kabir, Kenneth G Furton, José Juan Santana-Rodríguez
Benzotriazole UV stabilizers (BUVSs) are a group of compounds added to personal care products such as sunscreens, hair dyes, make up formulations, soaps or shampoos, among others. Direct input from beaches or another aquatic recreational areas is the main source of BUVSs incorporation to the environment, where they can be mutagenic, toxic, pseudo-persistent and bioaccumulative. Due to the low levels of concentration of these compounds found in environmental samples, an extraction process is required prior to their determination...
December 2016: Chemosphere
https://www.readbyqxmd.com/read/27590880/hair-product-artifact-in-magnetic-resonance-imaging
#19
Sneha Chenji, Alan H Wilman, Dennell Mah, Peter Seres, Angela Genge, Sanjay Kalra
The presence of metallic compounds in facial cosmetics and permanent tattoos may affect the quality of magnetic resonance imaging. We report a case study describing a signal artifact due to the use of a leave-on powdered hair dye. On reviewing the ingredients of the product, it was found to contain several metallic compounds. In lieu of this observation, we suggest that MRI centers include the use of metal- or mineral-based facial cosmetics or hair products in their screening protocols.
August 30, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27552174/lack-of-information-received-by-a-french-female-cohort-regarding-prevention-against-exposure-to-reprotoxic-agents-during-pregnancy
#20
REVIEW
Marie-Charlotte Chabert, Jeanne Perrin, Julie Berbis, Florence Bretelle, Sébastien Adnot, Blandine Courbiere
OBJECTIVE: The aim of this study was to evaluate the information pregnant women received regarding possible exposures to five recognized reprotoxic agents during their pregnancy. STUDY DESIGN: A cohort study was conducted using two postnatal units in France. Women hospitalized in postnatal units were requested to complete a self-administered two part questionnaire. The first part gathered information about the patient's socio-professional level and the type of pregnancy follow-up...
October 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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