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Betty-Shannon Prevatt, Evan M Lowder, Sarah L Desmarais
OBJECTIVE: Postpartum mood disorders represent a serious problem affecting 10-20% of women and support groups offer a promising intervention modality. The current study examined participant satisfaction with and effectiveness of a peer-facilitated postpartum support group. INTERVENTION: The program consists of a free, peer-support group, developed to increase social support and destigmatise postpartum mood symptoms. The weekly group is co-facilitated by former group attendees and maternal health professionals...
May 31, 2018: Midwifery
Shanshan Li, Weiqiang Zhong, Wen Peng, Gaofeng Jiang
OBJECTIVE: To assess the clinical effectiveness of acupuncture in the treatment of postpartum depression (PPD). METHODS: The following electronic databases were systematically searched: PubMed, Cochrane Library, SCI, Elsevier SDOL, China National Knowledge, Wan Fang database and Chinese Science and Technology Periodical Database. Only randomised controlled trials (RCTs) of acupuncture for PPD were considered. Primary outcomes were the Hamilton Rating Scale for Depression (HAMD) or the Edinburgh Postnatal Depression Scale (EPDS) scores and effective rate...
June 15, 2018: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
Zifeng Guo, Dijun Chen, Marion Roeder, Martin Ganal, Thorsten Schnurbusch
Flowering time is an important factor affecting grain yield in wheat. In this study, we divided reproductive spike development into eight sub-phases. These sub-phases have the potential to be delicately manipulated to increase grain yield. We measured 36 traits with regard to sub-phase durations, determined three grain yield-related traits in eight field environments and mapped 15,696 single nucleotide polymorphism (SNP, based on 90k Infinium chip and 35k Affymetrix chip) markers in 210 wheat genotypes. Phenotypic and genetic associations between grain yield traits and sub-phase durations show significant consistency (Mantel test r = 0...
June 15, 2018: Plant Journal: for Cell and Molecular Biology
Hashima E Nasreen, Jamalludin Ab Rahman, Razman Mohd Rus, Mira Kartiwi, Rosnah Sutan, Maigun Edhborg
BACKGROUND: Research on antepartum psychiatric morbidities investigating depressive and anxiety symptoms in expectant mothers and fathers is lacking in low- and middle-income countries. This study aimed to estimate the prevalence of antepartum depressive, anxiety and co-occurring significant symptoms and explore the associated factors in a cross-section of Malaysian expectant mothers and fathers. METHODS: We used cross-sectional data from a prospective cohort study of 911 expectant mothers and 587 expectant fathers during their third trimester of pregnancy, from health clinics of two states in the east and west coasts of Malaysia...
June 15, 2018: BMC Psychiatry
Marion I van den Heuvel, Marcel A L M van Assen, Vivette Glover, Stephan Claes, Bea R H Van den Bergh
BACKGROUND: Maternal psychological distress during pregnancy is related to adverse child behavioral and emotional outcomes later in life, such as ADHD and anxiety/depression. The underlying mechanisms for this, however, are still largely unknown. The hypothalamic-pituitary-adrenal (HPA)-axis, with its most important effector hormone cortisol, has been proposed as a mechanism, but results have been inconsistent. The current study investigated the association between maternal psychological distress (i...
June 5, 2018: Psychoneuroendocrinology
Shikha Tewari, Geetanjali Sharma, Sanjay Tewari, Shweta Mittal, Shweta Bansal
Background and objective: Management of combined endodontic-periodontal lesions needs more clinical investigations. The aim of this prospective randomized clinical trial was to evaluate the effect oftime interval between the non-surgical endodontic treatment (ET) and open flap debridement (OFD) on periodontal healing in combined endodontic periodontal lesions with apical communication. Methods: Forty patients were randomly allocated to two treatment protocols. Group 1(immediate periodontal surgery): OFD was performed at 21 days of initiation of ET and SRP, and Group 2(delayed periodontal surgery): OFD was performed after 3 months of initiation of ET and SRP...
May 2018: Journal of Oral Biology and Craniofacial Research
Dan-Qing Liu, Zhi-Qiang Cheng, Qing-Jie Feng, He-Jie Li, Shu-Feng Ye, Bo Teng
In this work, 20( S )-protopanaxadiol (PPD)-loaded polycaprolactone (PCL) nanofibres were successfully fabricated by the electrospinning technique using Tween 80 as a solubilizer. Firstly, smooth and continuous nanofibres were collected using suitable solvents and appropriate spinning conditions. Secondly, nanofibre mats were characterized by scanning electron microscopy, thermogravimetric (TG) analysis, Fourier transform infrared spectroscopy and mechanical testing. Finally, nanofibrous membranes were evaluated using water contact angle, in vitro drug release, biodegradation test, in vitro and in vivo anti-tumour activity and cell apoptosis assay...
May 2018: Royal Society Open Science
Ernesto González-Mesa, Kamile Kabukcuoglu, Oznur Körükcü, Marta Blasco, Nadia Ibrahim, Türker Kavas
BACKGROUND: Depression is the most frequent mental disorder during pregnancy, and its prevalence is at least as high as that of postnatal depression. Differences between Western and Eastern countries may exist according to cultural and educational factors. OBJECTIVE: to determine the influence of social and cultural factors on the mood state of a multicultural sample of 514 Turkish and Spanish pregnant women at the beginning of the pregnancy. METHODS: Between October and December 2017 250 Turkish and 264 Spanish pregnant women attending their first pregnancy medical check-up between 10 and 12 weeks of pregnancy were recruited (264 in Málaga, 102 in Istanbul and 148 in Antalya)...
June 2, 2018: Journal of Affective Disorders
Jennifer L Heck
This review examined validation studies of the Edinburgh Postnatal Depression Scale (EPDS) and the Patient Health Questionnaire-9 (PHQ-9) to identify an appropriate postpartum depression (PPD) screening tool for American Indian and Alaska Native (AI/AN) women in the U.S. Databases were searched using: EPDS paired with psychometric properties or validation and PHQ-9 paired with PPD and psychometric properties or validation, yielding a final sample of 58 articles. Both tools have good internal consistency, but discriminative validity for detecting PPD in women from non-Western cultures is low...
2018: American Indian and Alaska Native Mental Health Research: the Journal of the National Center
Jeneen Panezai, Ambereen Ghaffar, Mohammad Altamash, Per-Erik Engström, Anders Larsson
BACKGROUND: Periodontal disease (PD) and rheumatoid arthritis (RA) are bone pathologies mediated through immuno-inflammatory mechanisms. The aim of this study was to investigate the serum markers osteopontin (OPN), tumor necrosis factor receptors 1 (TNFR1) and 2 (TNFR2) receptor activator of nuclear factor-kappa B ligand (RANKL) and RANKL/ osteoprotegerin (OPG) ratio and compare them in PD and RA groups. MATERIALS & METHODS: RA (with PD = 19 and without PD = 19), PD (n = 38) and 14 healthy subjects underwent bleeding on probing (BOP) and probing pocket depth (PPD) measurement...
2018: PloS One
Wenli Pan, Binli Xue, Chulei Yang, Linlin Miao, Lingli Zhou, Queyue Chen, Qing Cai, Yi Liu, Dongchun Liu, Haibing He, Yu Zhang, Tian Yin, Xing Tang
Deglycosylation is the most important gastrointestinal metabolism which ginsenosides are split off from glycosyl moieties by the enzymes secreted from intestinal microflora, and two possible metabolic pathways of protopanaxdiol-type and protopanaxtriol-type ginsenosides have been concluded. The former is deglycosylated at C-3 and/or C-20, and transformed to protopanaxdiol (PPD). By comparison, the latter is deglycosylated at C-6 and/or C-20, and eventually transformed to protopanaxtriol (PPT) instead. The pharmacokinetic behavior of protopanaxdiol-type ginsenosides (PPD-type ginsenosides) and protopanaxtriol-type ginsenosides (PPT-type ginsenosides) is different, mainly in a faster absorption and elimination rate of PPD-type ginsenosides, but almost all of ginsenosides have a low oral bioavailability, which is relevant to the properties, the stability in the gastrointestinal tract, membrane permeability and the intestinal and hepatic first-pass effect of ginsenosides...
June 5, 2018: Fitoterapia
Mimi Tang, Yiping Liu, Lu Wang, Huande Li, Hualin Cai, Min Zhang, Ruili Dang, Ying Xue, Yanqin Wu
Low intake of omega-3 (Ω-3) polyunsaturated fatty acids (PUFAs) especially docosahexaenoic acid (DHA) is associated with postpartum depression. DHA deficiency is accompanied by impaired attention and cognition, and will precipitate psychiatric symptoms. However, the effects of dietary DHA on postpartum depression remain unclear. We established a normal pregnancy model to evaluate whether an Ω-3 PUFA-deficient diet during gestation could induce depressive-like behavior and aggravate dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis in rats...
June 8, 2018: Food & Function
Tim Carter, Anastasios Bastounis, Boliang Guo, C Jane Morrell
Postpartum depression can have detrimental effects on both a mother's physical and mental health and on her child's growth and emotional development. The aim of this study is to assess the effectiveness of exercise/physical activity-based interventions in preventing and treating postpartum depressive symptoms in primiparous and multiparous women to the end of the postnatal period at 52 weeks postpartum. Electronic databases were searched for published and unpublished randomised controlled trials of exercise/physical activity-based interventions in preventing and treating depressive symptoms and increasing health-related quality of life in women from 4 to 52 weeks postpartum...
June 7, 2018: Archives of Women's Mental Health
Elena Ali
Purpose: Postpartum anxiety disorders are common and may have significant consequences for mothers and their children. This review examines the literature on women's experiences with postpartum generalized anxiety disorder (GAD), postpartum panic disorder (PD), obsessive compulsive disorder (OCD), and posttraumatic stress disorder (PTSD). Methods: MEDLINE (Ovid), CINAHL, PsycINFO, and reference lists were searched. Qualitative and quantitative studies assessing women's experiences with GAD, postpartum PD, OCD, and PTSD were included...
2018: International Journal of Women's Health
Julie D Flom, Yueh-Hsiu Mathilda Chiu, Marcela Tamayo-Ortiz, Lourdes Schnaas, Paul C Curtin, Rosalind J Wright, Robert O Wright, Martha M Téllez-Rojo, Maria José Rosa
BACKGROUND: Postpartum depression is an important cause of morbidity in mothers and children. The Edinburgh Postpartum Depression Scale (EPDS), the most widely used self-reported measure of postpartum depression, was conceived as a one-dimensional measure. However, evidence that depressive symptoms may be experienced differentially across cultural and racial groups highlights the need to examine structural equivalence using factor analysis across populations. Variation in factor structure for the EPDS remains understudied in middle/low income countries...
May 29, 2018: Journal of Affective Disorders
Ana Fonseca, Fabiana Monteiro, Maria Cristina Canavarro
OBJECTIVE: This study aimed to examine the relationship between dysfunctional motherhood-related beliefs and postpartum anxiety and depression symptoms, and whether experiential avoidance may be a potential mechanism in explaining these relationships. METHOD: A sample of 262 postpartum women participated in a cross-sectional online survey. RESULTS: The model presented a good fit (CFI = 0.96, RMSEA = 0.077) suggesting that more dysfunctional motherhood-related beliefs related with maternal responsibility and with others' judgments were associated with higher postpartum anxiety and depressive symptoms...
June 6, 2018: Journal of Clinical Psychology
Josephus Fm van den Heuvel, T Katrien Groenhof, Jan Hw Veerbeek, Wouter W van Solinge, A Titia Lely, Arie Franx, Mireille N Bekker
BACKGROUND: Unrestricted by time and place, electronic health (eHealth) provides solutions for patient empowerment and value-based health care. Women in the reproductive age are particularly frequent users of internet, social media, and smartphone apps. Therefore, the pregnant patient seems to be a prime candidate for eHealth-supported health care with telemedicine for fetal and maternal conditions. OBJECTIVE: This study aims to review the current literature on eHealth developments in pregnancy to assess this new generation of perinatal care...
June 5, 2018: Journal of Medical Internet Research
Gokul Raj Kathamuthu, Nathella Pavan Kumar, Kadar Moideen, Dhanaraj Baskaran, Syed Hissar, Basavegowdanadoddi M Shrinivasa, Rathinam Sridhar, Subash Babu
BACKGROUND: IL-10 family cytokines are associated with the host immune response to pulmonary tuberculosis (PTB), but their association with host response in tuberculous lymphadenitis (TBL) is not known. METHODS: Hence, we examined the circulating levels of the whole panel of IL-10 family cytokines in TBL (n = 44) and compared them to the levels in PTB (n = 44) and healthy control (HC, n = 44) individuals. We also assessed the pre and post-treatment cytokine levels in TBL individuals following the completion of anti-tuberculosis treatment (ATT)...
June 2, 2018: Cytokine
Vanessa Wall, Shahirose Sadrudin Premji, Nicole Letourneau, Graham McCaffrey, Elias Charles Nyanza
OBJECTIVE: To identify factors predictive of pregnancy-related anxiety (PRA) among women in Mwanza, Tanzania. DESIGN: A cross-sectional study was used to explore the relationship between psychosocial health and preterm birth. SETTING: Antenatal clinics in the Ilemela and Nyamagana districts of Mwanza, Tanzania. PARTICIPANTS: Pregnant women less than or equal to 32 weeks' gestational age (n=212) attending the two antenatal clinics...
June 4, 2018: BMJ Open
Tu-Chen Chung, Chi-Hsiang Chung, Hsuan-Ju Peng, Chang-Huei Tsao, Wu-Chien Chien, Huey-Fang Sun
Postpartum depression has become an important topic of concern in recent years. However, very few studies on the causes of postpartum depression exist, and the effects of prenatal sleep disorders on the development of postpartum depression among pregnant women have not been elucidated. This study aimed to understand the association between prenatal sleep disorders and postpartum depression. The National Health Insurance Research Database of Taiwan (between 2000 and 2010) was used to assess the effects of prenatal sleep disorder on the risk of postpartum depression using Cox regression analyses...
May 18, 2018: Oncotarget
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