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https://www.readbyqxmd.com/read/29723632/phenotypic-markers-of-oral-keratinocytes-seeded-on-two-distinct-3d-oral-mucosa-models
#1
Fernanda G Basso, Taisa N Pansani, Cyntia L Marcelo, Carlos Alberto de Souza Costa, Josimeri Hebling, Stephen E Feinberg
This study validates the use of a full-thickness oral mucosa model for in vitro studies with a collagen type I matrix, by comparison of this model with two other 3D oral mucosa models: human-sourced and porcine acellular dermal matrices (AlloDerm®/Strattice®, respectively). For the collagen matrix model, gingival fibroblasts were seeded either onto the dermal side of the AlloDerm® and Strattice® matrices or within the collagen matrices in complete culture medium (DMEM). For all scaffolds, DMEM was replaced every 24 h up to 72 h...
April 30, 2018: Toxicology in Vitro: An International Journal Published in Association with BIBRA
https://www.readbyqxmd.com/read/29707460/comparing-the-outcome-of-different-biologically-derived-acellular-dermal-matrices-in-implant-based-immediate-breast-reconstruction-a-meta-analysis-of-the-literatures
#2
Yew L Loo, Pragash Kamalathevan, Peng S Ooi, Afshin Mosahebi
Background: Acellular dermal matrices (ADMs) have been used extensively in implant-based breast reconstruction. It was reported that due to the different sources and processing methods, the outcomes of ADMs in implant-based breast reconstructions are expected to differ. We designed this study to statistically analyze and discuss the outcome of 3 commonly used ADMs, Alloderm, Strattice, and Surgimend in implant-based breast reconstruction. Methods: Comprehensive review of the literatures searched on electronic databases was done to identify studies published between 2006 and 2017 comparing the outcome of ADMs...
March 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29697602/a-prospective-comparison-of-short-term-outcomes-of-subpectoral-and-prepectoral-strattice-based-immediate-breast-reconstruction
#3
Benjamin G Baker, Renu Irri, Vivienne MacCallum, Rahul Chattopadhyay, John Murphy, James R Harvey
BACKGROUND: Prepectoral acellular dermal matrix-assisted immediate implant-based breast reconstruction is gaining popularity, involving complete implant coverage with acellular dermal matrix. The authors aimed to compare pain, patient-reported outcome measures (including implant rippling), and safety of prepectoral and subpectoral Strattice-assisted implant-based breast reconstruction. METHODS: Consecutive patients were recruited prospectively, having either therapeutic or risk-reducing mastectomy...
May 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29501796/biological-meshes-for-abdominal-hernia-lack-of-evidence-based-recommendations-for-clinical-use
#4
REVIEW
Sabrina Trippoli, Erminia Caccese, Giorgio Tulli, Pierluigi Ipponi, Claudio Marinai, Andrea Messori
BACKGROUND: In the clinical literature on abdominal hernia repair, no sound criteria have been established to support the use of biological meshes as opposed to synthetic ones. Furthermore, the information on biological meshes is quite scarce, and so their place in therapy has not yet been defined. METHODS: The treatment of primary and incisional ventral hernia was the target intervention evaluated in our analysis. Our study consisted of the following phases: a) Identification of the biologic meshes available on the market; b) Literature search focused on efficacy and safety of these meshes; c) Analysis of the findings derived from the literature search...
April 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29417284/biologic-meshes-and-synthetic-meshes-in-cancer-patients-a-double-edged-sword-differences-in-production-of-il-6-and-il-12-caused-by-acellular-dermal-matrices-in-human-immune-cells
#5
Maria Margarete Karsten, Sabine Enders, Julia Knabl, Verena Kirn, Peter Düwell, Brigitte Rack, Jens-Uwe Blohmer, Doris Mayr, Darius Dian
PURPOSE: In 2005, Breuing et al. first described the use of acellular dermal matrices (ADMs) in breast cancer patients. ADMs are assumed to be safe to use in an oncologic setting, but data from controlled studies are still needed. Here, we investigate the effects of ADMs on the production of interleukin (IL)-6 and IL-12, key regulators of immune suppression and activation. METHODS: Strattice (ST), CollaMend (CM), and Biodesign (BD) biologic meshes and TiLoop, a synthetic mesh (TL), were used in this study...
May 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29369979/the-comparison-of-strattice-and-surgimend-in-acellular-dermal-matrix-assisted-implant-based-immediate-breast-reconstruction
#6
Fayyaz A K Mazari, Ghulam M Wattoo, Nazar H Kazzazi, Kadappa M Kolar, Olumuyiwa O Olubowale, Clare E Rogers, Iman A Azmy
BACKGROUND: Strattice (porcine derivative) and SurgiMend (bovine derivative) are the two most common acellular dermal matrices used in breast reconstruction in the United Kingdom. This retrospective study compared clinical outcomes in immediate implant-based breast reconstruction patients. METHODS: The study, conducted across three hospitals, included all patients who underwent immediate implant-based breast reconstruction using Strattice and SurgiMend. The primary outcome measure was implant loss rate...
February 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28901533/characteristics-of-different-mesh-types-for-abdominal-wall-repair-in-an-experimental-model-of-peritonitis
#7
R Kaufmann, A P Jairam, I M Mulder, Z Wu, J Verhelst, S Vennix, L J X Giesen, M C Clahsen-van Groningen, J Jeekel, J F Lange
BACKGROUND: The use of synthetic mesh to repair a potentially contaminated incisional hernia may lead to higher failure rates. A biological mesh might be considered, but little is known about long-term results. Both biological and synthetic meshes were investigated in an experimental model of peritonitis to assess their characteristics in vivo. METHODS: Male Wistar rats were randomized into five groups and peritonitis was induced. A mesh was implanted after 24 h...
December 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28894654/evaluation-of-a-novel-hybrid-viable-bioprosthetic-mesh-in-a-model-of-mesh-infection
#8
Ally Ha, Erik T Criman, Wendy E Kurata, Karen W Matsumoto, Lisa M Pierce
BACKGROUND: The reported incidence of mesh infection in contaminated operative fields is as high as 30% regardless of material used. Our laboratory previously showed that augmenting acellular bioprosthetic mesh with allogeneic mesenchymal stem cells (MSC) enhances resistance to bacterial colonization in vivo and preserves mesh integrity. This study's aim was to determine whether augmentation of non-crosslinked porcine dermis (Strattice) with commercially available, cryopreserved, viable MSC-containing human placental tissue (Stravix) similarly improves infection resistance after inoculation with Escherichia coli (E...
August 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28633126/emergency-incarcerated-obturator-hernia-repair-with-biologic-mesh-in-a-male-patient-after-ipsilateral-hip-disarticulation-a-case-report
#9
Rodolfo J Oviedo, Alexander H W Molinari
INTRODUCTION: An obturator hernia is an uncommon form of abdominal hernia that is difficult to diagnose due to its non-distinct presentation. This case investigates an emergency treatment of an obturator hernia presenting in a patient with an ipsilateral hip disarticulation in a 266-bed community hospital. PRESENTATION OF CASE: A 53-year old man with a history of a left hip disarticulation 3-weeks prior presented to the emergency department with fever, nausea, vomiting, and diarrhea for the past 5-days...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28624524/a-direct-comparison-of-porcine-strattice%C3%A2-and-bovine-surgimend%C3%A2-acellular-dermal-matrices-in-implant-based-immediate-breast-reconstruction
#10
COMPARATIVE STUDY
Jessica F Ball, Yezen Sheena, Dina M Tarek Saleh, Parto Forouhi, Sarah L Benyon, Michael S Irwin, Charles M Malata
INTRODUCTION: Acellular dermal matrix (ADM) assisted implant-based breast reconstruction (IBBR) has grown in popularity over traditional submuscular techniques. Numerous human, bovine or porcine derived ADMs are available with the type used varying considerably worldwide. Yet, comparative evidence for the efficacy of different ADMs particularly xenogenic is limited. This study directly compares early outcomes of porcine (Strattice™) and bovine (Surgimend™) ADMs in IBBR. METHOD: Retrospective study of sequential experience of immediate IBBR using Strattice or Surgimend ADM...
August 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28492357/long-term-effectiveness-of-strattice-in-the-laparoscopic-closure-of-paraesophageal-hernias
#11
Daniel Lomelin, Alicia Smith, Nathan Bills, Amareshewar Chiruvella, Christopher Crawford, Crystal Krause, Robert Bayer, Dmitry Oleynikov
Prosthetic reinforcement reduces the recurrence rate of large paraesophageal hernias (PEH), but the use of synthetic or biosynthetic mesh in the repair remains controversial. PEH repair has reported recurrence rates of 12% to 42%, and primary repair of PEH by suture closure under tension is at high risk of disruption. Synthetic mesh use in large PEH repair has shown to reduce recurrence but can lead to problems including mesh erosion, ulceration, stricture, and dysphagia. The objective of this study was to examine the long-term safety and efficacy of Strattice biologic mesh, a porcine acellular dermal matrix, in crural reinforcement of laparoscopic large PEH repair...
June 2017: Surgical Innovation
https://www.readbyqxmd.com/read/28457335/characterization-of-ventral-incisional-hernia-and-repair-using-shear-wave-elastography
#12
Anuj Chaudhry, Joseph S Fernandez-Moure, Peer Shafeeq Shajudeen, Jeffrey L Van Eps, Fernando J Cabrera, Bradley K Weiner, Brian J Dunkin, Ennio Tasciotti, Raffaella Righetti
BACKGROUND: To assess the integrity of hernia repair, imaging modalities such as computed tomography or ultrasound (US) are commonly used. Neither modality has currently the capacity to simultaneously image the mesh and quantify a prosthetic and surrounding tissue stiffness. In this pilot study, we hypothesize that US shear wave elastography (SWE) can be used to identify a polyester mesh and a biologic graft and to assess their stiffness noninvasively in a rat model of bridging hernia repair...
April 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28318504/-economic-evaluation-of-medical-devices-not-included-in-the-french-list-of-products-and-services-qualifying-for-reimbursement-example-of-biologic-meshes
#13
A Sainfort, I Denis-Hallouard, G Aulagner, O Nuiry, X Armoiry
OBJECTIVES: To present a method aimed to evaluate the economic impact associated with the use of medical devices (DM) not reimbursed in addition to diagnosis related groups (DRGs) tariffs using the example of biological meshes for parietal reinforcement. METHODS: In this multicenter retrospective cohort study, we included all patients who received a biological mesh between January 2010-April 2014 (University hospitals of Saint-Étienne, France) or between January 2010-March 2015 (Lyon University hospitals, France)...
March 16, 2017: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/28282003/complex-ventral-hernia-repair-with-acellular-dermal-matrices-clinical-and-quality-of-life-outcomes
#14
John Scott Roth, Amanda Zachem, Margaret A Plymale, Daniel L Davenport
Acellular dermal matrices (ADMs) are used in conjunction with complex hernia repair, but their efficacy is often debated. This study assesses clinical and quality of life (QOL) outcomes in multiply comorbid patients undergoing complex ventral hernia repair using ADMs. After obtaining institutional review board approval, a prospective study was conducted evaluating patients undergoing complex ventral incisional hernia repair with abdominal wall reconstruction (AWR) using either human (Flex HD) or porcine ADM (Strattice)...
February 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28265733/major-complex-abdominal-wall-repair-in-contaminated-fields-with-use-of-a-non-cross-linked-biologic-mesh-a-dual-institutional-experience
#15
J J Atema, E J Furnée, Y Maeda, J Warusavitarne, P J Tanis, W A Bemelman, C J Vaizey, M A Boermeester
BACKGROUND: Data on the use of biologic mesh in abdominal wall repair in complex cases remain sparse. Aim of this study was to evaluate a non-cross-linked porcine acellular dermal matrix for repair of complex contaminated abdominal wall defects. METHODS: Retrospective observational cohort study of consecutive patients undergoing abdominal wall repair with use of Strattice™ Reconstructive Tissue Matrix (LifeCell Corporation, Oxford, UK) between January 2011 and February 2015 at two National Intestinal Failure Units...
August 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28228200/complex-ventral-hernia-repair-with-acellular-dermal-matrices-clinical-and-quality-of-life-outcomes
#16
John Scott Roth, Amanda Zachem, Margaret A Plymale, Daniel L Davenport
Acellular dermal matrices (ADMs) are used in conjunction with complex hernia repair, but their efficacy is often debated. This study assesses clinical and quality of life (QOL) outcomes in multiply comorbid patients undergoing complex ventral hernia repair using ADMs. After obtaining institutional review board approval, a prospective study was conducted evaluating patients undergoing complex ventral incisional hernia repair with abdominal wall reconstruction (AWR) using either human (Flex HD) or porcine ADM (Strattice)...
February 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28214477/hospital-wide-porcine-mesh-conversion-results-in-cost-savings-with-equivalent-clinical-outcomes
#17
Nickolas Byrge, Mary C Mone, Daniel Vargo
BACKGROUND: A variety of biologic mesh is available for ventral hernia repair. Despite widely variable costs, there is no data comparing cost of material to clinical outcome. METHODS: Biologic mesh product change was examined. A prospective survey was done to determine appropriate biologic mesh utilization, followed by a retrospective chart review of those treated from Sept. 2012 to Aug. 2013 with Strattice™ and from Sept. 2013 to Aug. 2014 with Permacol™. Outcome variables included complications associated with each material, repair success, and cost difference over the two periods...
June 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28164146/dural-repair-using-porcine-adm-two-cases-and-a-literature-review
#18
Simon Skovsted Yde, Mette Eline Brunbjerg, Gudrun Gudmundsdottir, Mindaugas Bazys, Martin Heje, Tine Engberg Damsgaard
The use of acellular dermal matrices (ADM) for dural repair is very scantily described in the literature. We report two cases of dural repair using porcine ADM and a literature review. ADM and especially Strattice(TM) pliable may be a useful alternative to other dural substitutes. Further evaluation would be favorable.
2017: Case Reports in Plastic Surgery & Hand Surgery
https://www.readbyqxmd.com/read/28093117/the-biological-prosthesis-is-a-viable-option-for-abdominal-wall-reconstruction-in-pediatric-high-risk-defects
#19
COMPARATIVE STUDY
Osnat Zmora, Shannon L Castle, Stephanie Papillon, James E Stein
BACKGROUND: Our aim was to explore the indications for and outcome of biological prostheses to repair high risk abdominal wall defects in children. METHODS: A retrospective chart review was performed of all cases of abdominal wall reconstruction in a single institution between 2007 and 2015. Demographic and clinical variables, technique and complications were described and compared between prosthesis types. RESULTS: A total of 23 patients underwent abdominal wall reconstruction using a biological prosthesis including 17 neonates...
September 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28012977/two-stage-implant-based-breast-reconstruction-compared-with-immediate-one-stage-implant-based-breast-reconstruction-augmented-with-an-acellular-dermal-matrix-an-open-label-phase-4-multicentre-randomised-controlled-trial
#20
RANDOMIZED CONTROLLED TRIAL
Rieky E G Dikmans, Vera L Negenborn, Mark-Bram Bouman, Hay A H Winters, Jos W R Twisk, P Quinten Ruhé, Marc A M Mureau, Jan Maerten Smit, Stefania Tuinder, Yassir Eltahir, Nicole A Posch, Josephina M van Steveninck-Barends, Marleen A Meesters-Caberg, René R W J van der Hulst, Marco J P F Ritt, Margriet G Mullender
BACKGROUND: The evidence justifying the use of acellular dermal matrices (ADMs) in implant-based breast reconstruction (IBBR) is limited. We did a prospective randomised trial to compare the safety of IBBR with an ADM immediately after mastectomy with that of two-stage IBBR. METHODS: We did an open-label, randomised, controlled trial in eight hospitals in the Netherlands. Eligible women were older than 18 years with breast carcinoma or a gene mutation linked with breast cancer who intended to undergo skin-sparing mastectomy and immediate IBBR...
February 2017: Lancet Oncology
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