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https://www.readbyqxmd.com/read/29668080/control-of-the-ethylene-signaling-pathway-prevents-plant-defenses-during-intracellular-accommodation-of-the-rhizobia
#1
Fathi Berrabah, Thierry Balliau, El Hosseyn Aït-Salem, Jeoffrey George, Michel Zivy, Pascal Ratet, Benjamin Gourion
Massive intracellular populations of symbiotic bacteria, referred to as rhizobia, are housed in legume root nodules. Little is known about the mechanisms preventing the development of defense in these organs although genes such as symCRK and DNF2 of the model legume Medicago truncatula are required for this control after rhizobial internalization in host nodule cells. Here we investigated the molecular basis of the symbiotic control of immunity. Proteomic analysis was performed to compare functional (wild-type) and defending nodules (symCRK)...
April 18, 2018: New Phytologist
https://www.readbyqxmd.com/read/29667834/phase-transformation-of-geo2-glass-to-nanocrystals-under-ambient-condition
#2
Zhuohao Xiao, Xin-Yuan Sun, Xiuying Li, Yongqing Wang, Zhiqiang Wang, Bowei Zhang, Xianglin Li, Ze Xiang Shen, Lingbing Kong, Yizhong Huang
Theoretically, the accomplishment of phase transformation requires sufficient energy to overcome the barriers of structure rearrangements. Transition of an amorphous to crystalline structure is implemented traditionally by heating at high temperatures. However, phase transformation under ambient condition without involving external energy has not been reported. Here, we demonstrate that phase transformation of GeO2 glass to nanocrystals can be triggered at ambient condition when subjected to aqueous environments...
April 18, 2018: Nano Letters
https://www.readbyqxmd.com/read/29667812/turning-on-off-the-anti-tumor-effect-of-au-cluster-via-atomically-controlling-its-molecular-size
#3
Jiao Zhai, Yanwei Jia, Lina Zhao, Qing Yuan, Fuping Gao, Xiangchun Zhang, Pengju Cai, Liang Gao, Juanjuan Guo, Shuhong Yi, Zhifang Chai, Yuliang Zhao, Xueyun Gao
We reported two Au clusters with precisely controlled molecular size (Au5Peptide3 and Au22Peptide10) showing different anti-tumor effects. In vitro, both Au5Peptide3 and Au22Peptide10 were well taken up by human nasopharyngeal cancer cells (CNE1 cells). However, only Au5Peptide3 significantly induced CNE1 cell apoptosis. Further studies showed that CNE1 cells took up Au5Peptide3 (1.98*10-15 mol/cell) and 9% of them entered mitochondria (0.186*10-15 mol/cell). As a comparison, the uptake of Au22Peptide10 was only half the amount of Au5Peptide3 (1...
April 18, 2018: ACS Nano
https://www.readbyqxmd.com/read/29667749/effect-of-lysm-macrophage-depletion-on-lung-pathology-in-mice-with-chronic-bronchitis
#4
Yogesh Saini, Brandon W Lewis, Dongfang Yu, Hong Dang, Alessandra Livraghi-Butrico, Fabio Del Piero, Wanda K O'Neal, Richard C Boucher
Macrophages (MΦ) are key sentinels of respiratory exposure to inhaled environmental stimuli. In normal "healthy" tissues, MΦ are believed to be a dormant cell type that, upon exposure to stress-causing stimuli, may get activated to exhibit pro- or anti-inflammatory roles. To test whether stress present in chronic bronchitic (CB) airways triggers MΦ to manifest protective or detrimental responses, the DTA+ (LysM-regulated Diphtheria Toxin A expressing) strain with partial MΦ-deficiency was crossed with the Scnn1b-Tg mouse model of CB and the progenies were studied at 4-5 weeks of age...
April 2018: Physiological Reports
https://www.readbyqxmd.com/read/29667711/the-impact-of-the-legalisation-of-abortion-on-birth-outcomes-in-uruguay
#5
José-Ignacio Antón, Zuleika Ferre, Patricia Triunfo
This study investigates the short-term impact on the quantity and quality of births of an abortion reform in Uruguay that legalised termination of pregnancy until the 12th week of pregnancy in the short run. We employ a differences-in-differences approach, comprehensive administrative records of births, and a novel identification strategy based on the planned or unplanned nature of pregnancies that came to term. Our results suggest that this policy change has led to an 8% decline in the number of births from unplanned pregnancies, driven by the group of mothers aged between 20 and 34 years old who have secondary education...
April 18, 2018: Health Economics
https://www.readbyqxmd.com/read/29667696/degree-of-anger-during-anger-generating-situations-among-psychiatric-staff-nurses-association-between-nurses-attitudes-toward-service-users-aggression-and-confidence-in-intervening-in-aggressive-situations
#6
Seiji Shimosato, Aimi Kinoshita
Some situations require psychiatric staff nurses to respond to service users' negativity or aggression. As a result, psychiatric staff nurses may experience anger. The current study examined how anger levels of psychiatric staff nurses triggered by anger-generating situations by service users affected nurses' confidence and attitudes. A questionnaire survey was administered among 386 psychiatric staff nurses. The questionnaire surveyed anger levels in anger-generating situations, aggressiveness, nurses' attitudes toward aggression, and self-efficacy of intervening in aggressive situations...
April 17, 2018: Journal of Psychosocial Nursing and Mental Health Services
https://www.readbyqxmd.com/read/29667662/camel-milk-attenuates-methotrexate-induced-kidney-injury-via-activation-of-pi3k-akt-enos-signaling-and-intervention-with-oxidative-aberrations
#7
Hany H Arab, Samir A Salama, Ibrahim A Maghrabi
Methotrexate (MTX) is a classical chemotherapeutic agent with nephrotoxicity as the most disturbing adverse effect. So far, its underlying molecular mechanisms, particularly PI3K/Akt/eNOS transduction, are inadequately explored. Several antioxidant modalities have been characterized to ameliorate MTX-induced renal injury. In this regard, Camel milk (CM) is a natural product with recognized antioxidant and anti-inflammatory features. Thus, the current study aimed to investigate the potential ameliorating effects of CM in MTX-induced kidney injury in rats...
April 18, 2018: Food & Function
https://www.readbyqxmd.com/read/29667408/a-redox-active-cobalt-ii-iii-metal-organic-framework-for-selective-oxidation-of-cyclohexene
#8
Tao Zhang, Yue-Qiao Hu, Tian Han, Yuan-Qi Zhai, Yan-Zhen Zheng
We report herein a new cobalt(II/III) mixed-valance metal-organic framework (MOF) fomulated as [CoIICo2III(μ3-O)(bdc)3(tpt)]•Guest 1, where bdc = benzene-1,4-dicarboxylate and tpt = 2,4,6-tri(4-pyridinyl)-1,3,5-triazine, can be used as a redox-active heterogeneous catalyst for selective oxidation of cyclohexene on the allylic position without destroying the adjacent double bond. Two oxidants were chosen to demonstrate this result. For using tert-butyl hydroperoxide, the conversion rate is 63 % and only allylic oxidation products (tert-butyl-2-cyclohexenyl-1-peroxide, 86 %; 2-cyclohexen-1-one, 14 %) are found...
April 18, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29667404/silver-ion-as-a-novel-coreaction-accelerator-for-remarkably-enhanced-electrochemiluminescence-of-ptca-s2o82-system-and-its-application-in-ultrasensitive-assay-of-mercury-ion
#9
Yan-Mei Lei, Rui-Xin Wen, Jia Zhou, Ya-Qin Chai, Ruo Yuan, Ying Zhuo
In this work, with the use of Ag (I) ion as a robust coreaction accelerator toward enhancement of 3,4,9,10-perylenetetracarboxylic acid/peroxydisulfate (PTCA/S2O82-) system, a highly sensitive solid-state electrochemiluminescence (ECL) biosensing platform was successfully designed for mercury ion (Hg2+) detection. Specifically, a long guanine-rich (C-rich) double-stranded DNA (dsDNA) was generated by the target Hg2+-controlled DNA machine, which could embed the Ag (I) ion for ECL signal amplification of PTCA/S2O82- system...
April 18, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29667254/adjustable-electrochemiluminescence-from-highly-passivated-cdte-cds-nanocrystals-via-simple-surface-decoration-with-counterions
#10
Yupeng He, Shifeng Hou, Liqiong Yang, Fang Zhang, Guizheng Zou
Tunable optics and electronics of II-VI nanocrystals (NCs) is mainly achieved in the traditional size-dependent strategy. Herein, adjustable triggering energy, intensity, and even spectrum for reductive-oxidation electrochemiluminescence (ECL) from highly-passivated CdTe/CdS NCs of the same size are achieved via decorating NCs with counterions, which proves surface chemistry can bring out varied electrostatic interaction between surface vacancies and electrochemically injected carriers for adjustable electrochemical redox induced radiative charge-transfer...
April 17, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29667081/the-schultz-midi-benchmarking-toolbox-for-midi-interfaces-percussion-pads-and-sound-cards
#11
Benjamin G Schultz
The Musical Instrument Digital Interface (MIDI) was readily adopted for auditory sensorimotor synchronization experiments. These experiments typically use MIDI percussion pads to collect responses, a MIDI-USB converter (or MIDI-PCI interface) to record responses on a PC and manipulate feedback, and an external MIDI sound module to generate auditory feedback. Previous studies have suggested that auditory feedback latencies can be introduced by these devices. The Schultz MIDI Benchmarking Toolbox (SMIDIBT) is an open-source, Arduino-based package designed to measure the point-to-point latencies incurred by several devices used in the generation of response-triggered auditory feedback...
April 17, 2018: Behavior Research Methods
https://www.readbyqxmd.com/read/29667032/contrast-opacification-difference-of-mural-artery-and-the-transluminal-attenuation-gradient-on-coronary-computed-tomography-angiography-for-detection-of-systolic-compression-of-myocardial-bridge
#12
Yuanliang Xie, Xiang Wang, Wei Xie, Faxiang Chen, Shubo Gao, Yikai Xu
PURPOSE: Myocardial bridges (MB) have traditionally been considered a benign condition, but recent studies have demonstrated that the clinical complications can be dangerous. The transluminal attenuation gradient (TAG) obtained from coronary computed tomography angiography (CCTA) data (Retrospective ECG-triggered method) has been used in detecting significant stenosis in coronary artery caused by atherosclerosis. Contrast opacification difference (COD) was the parameters calculated as the change between attenuation of mural artery and the median attenuation of presumptive vessel segment; it was evaluated along with TAGstandardized (TAGs) and MB length for predicting MB with systolic compression (MB-SC) in patients diagnosed as MB in left anterior descending coronary artery (LAD) by CCTA or invasive coronary angiograph (ICA)...
April 17, 2018: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/29667027/neonatal-overfeeding-impairs-differentiation-potential-of-mice-subcutaneous-adipose-mesenchymal-stem-cells
#13
Isabelle Dias, Ísis Salviano, André Mencalha, Simone Nunes de Carvalho, Alessandra Alves Thole, Laís Carvalho, Erika Cortez, Ana Carolina Stumbo
Nutritional changes in the development (intrauterine life and postnatal period) may trigger long-term pathophysiological complications such as obesity and cardiovascular disease. Metabolic programming leads to organs and tissues modifications, including adipose tissue, with increased lipogenesis, production of inflammatory cytokines, and decreased glucose uptake. However, stem cells participation in adipose tissue dysfunctions triggered by overfeeding during lactation has not been elucidated. Therefore, this study was the first to evaluate the effect of metabolic programming on adipose mesenchymal stem cells (ASC) from mice submitted to overfeeding during lactation, using the litter reduction model...
April 17, 2018: Stem Cell Reviews
https://www.readbyqxmd.com/read/29666955/charge-ordering-in-the-metal-insulator-transition-of-v-doped-cro-2-in-the-rutile-structure
#14
Sarajit Biswas
Electronic, magnetic, and structural properties of pure and V-doped CrO2 were extensively investigated utilizing density functional theory. Usually, pure CrO2 is a half-metallic ferromagnet with conductive spin majority species and insulating spin minority species. This system remains in its half-metallic ferromagnetic phase even at 50% V-substitution for Cr within the crystal. The V-substituted compound Cr0.5 V0.5 O2 encounters metal-insulator transition upon the application of on-site Coulomb repulsion U = 7 eV preserving its ferromagnetism in the insulating phase...
April 17, 2018: Journal of Molecular Modeling
https://www.readbyqxmd.com/read/29666912/magnetic-bead-capture-dna-glucose-loaded-nanoliposomes-for-amplifying-the-glucometer-signal-in-the-rapid-screening-of-hepatitis-c-virus-rna
#15
Haijian Tu, Kun Lin, Yongzhi Lun, Liuming Yu
A digital detection strategy based on a portable personal glucometer (PGM) was developed for the simple, rapid, and sensitive detection of hepatitis C virus (HCV) RNA, involving the release of glucose-loaded nanoliposomes due to coupling-site-specific cleavage by the endonuclease BamHI. The glucose-loaded nanoliposomes were synthesized using a reversed-phase evaporation method and provided an amplified signal at the PGM in the presence of HCV RNA. Initially, a 21-mer oligonucleotide complementary to HCV RNA was covalently conjugated to a magnetic bead through the amino group at the 5' end of the oligonucleotide, and then bound to a glucose-loaded liposome by typical carbodiimide coupling at its 3' end...
April 17, 2018: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29666887/reversible-lesions-of-the-corpus-callosum-with-initially-restricted-diffusion-in-a-series-of-caucasian-children
#16
Anthony Le Bras, Maia Proisy, Mathieu Kuchenbuch, Constantin Gomes, Catherine Tréguier, Sylvia Napuri, Emmanuel Quehen, Bertrand Bruneau
BACKGROUND: Reversible lesions of the corpus callosum with initial restricted diffusion on diffusion-weighted imaging (DWI) are rare and mainly described in the south Asiatic population. OBJECTIVE: The purpose of this study was to describe the clinical presentation, imaging findings, prognosis and etiology of transient restricted diffusion lesions of the corpus callosum in a series of Caucasian children. MATERIALS AND METHODS: Seven children presenting with a transient restricted DWI lesion of the corpus callosum were included...
April 17, 2018: Pediatric Radiology
https://www.readbyqxmd.com/read/29666865/preparation-of-lactic-acid-and-glucose-responsive-poly-%C3%AE%C2%B5-caprolactone-b-poly-ethylene-oxide-block-copolymer-micelles-using-phenylboronic-ester-as-a-sensitive-block-linkage
#17
David Vrbata, Mariusz Uchman
The present study describes the synthesis, self-assembly and responsiveness to glucose and lactic acid of biocompatible and biodegradable block copolymer micelles using phenylboronic ester as the linkage between hydrophobic poly(ε-caprolactone) (PCL) and hydrophilic poly(ethylene oxide) (PEO). The PCL block with pendant phenylboronic acid (PCLBA) was synthesized by combining ε-caprolactone (ε-CL) ring-opening polymerisation (ROP), using 4-hydroxymethyl(phenylboronic) acid pinacolate as the initiator, and pinacol deprotection...
April 18, 2018: Nanoscale
https://www.readbyqxmd.com/read/29666845/investigating-contextual-cues-as-indicators-for-ema-delivery
#18
Varun Mishra, Kelly Caine, Byron Lowens, David Kotz, Sarah Lord
In this work, we attempt to determine whether the contextual information of a participant can be used to predict whether the participant will respond to a particular Ecological Momentary Assessment (EMA) trigger. We use a publicly available dataset for our work, and find that by using basic contextual features about the participant's activity, conversation status, audio, and location, we can predict if an EMA triggered at a particular time will be answered with a precision of 0.647, which is significantly higher than a baseline precision of 0...
September 2017: Proceedings of the ACM International Conference on Ubiquitous Computing
https://www.readbyqxmd.com/read/29666725/elevated-serum-igg4-levels-in-a-young-patient-with-polyserositis-and-necator-americanus-infection
#19
Giuseppe D Sanna, Roberto Manetti, Valentina de Filippo, Sergio Babudieri
IgG4-related disease is a fibroinflammatory systemic condition characterized by tumefactive lesions, lymphoplasmacytic infiltrate rich in IgG4-positive plasma cells, storiform fibrosis, and elevated serum IgG4 concentrations. It has been described in virtually every organ system. Autoimmunity and infectious agents are potential immunologic triggers in IgG4-related disease. Herein, we describe a peculiar case of effusive-constrictive pericarditis in an 18-year-old boy with polyserositis and concomitant Necator americanus infection...
2018: Case Reports in Immunology
https://www.readbyqxmd.com/read/29666637/recovery-of-chronic-stress-triggered-changes-of-hippocampal-glutamatergic-transmission
#20
Min Lin, Gonglin Hou, Ying Zhao, Ti-Fei Yuan
Chronic stress results in neurochemical, physiological, immune, molecular, cellular, and structural changes in the brain and often dampens the cognition. The hippocampus has been one major focus in studying the stress responsivity and neural mechanisms underlying depression. Both acute and chronic stress stimuli lead to dynamic changes in excitatory transmission in the hippocampus. The present study examined the potential effects of spontaneous recovery after chronic stress on spatial memory function and glutamatergic transmission in the hippocampus...
2018: Neural Plasticity
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