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https://www.readbyqxmd.com/read/28048638/tu-d-201-04-veracity-of-data-elements-in-radiation-oncology-incident-learning-systems
#1
A Kapur, S Evans, D Brown, G Ezzell, D Hoopes, S Dieterich, K Kapetanovic, C Tomlinson
PURPOSE: Incident learning systems encompass volumes, varieties, values, and velocities of underlying data elements consistent with the V's of big data. Veracity, the 5th V however exists only if there is high inter-rater reliability (IRR) within the data elements. The purpose of this work was to assess IRR in the nationally deployed RO-ILS: Radiation Oncology-Incident Learning System (R) sponsored by the American Society for Radiation Oncology (ASTRO) and the American Association of Physicists in Medicine (AAPM)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047975/su-f-t-223-radiotherapy-incident-reporting-and-analysis-system-riras-early-experience
#2
R Kapoor, D Burkett, E Leidholdt, J Palta, M Hagan
BACKGROUND & PURPOSE: RIRAS is a web-based information system deployed on the Veterans Health Administration intranet in early 2014 to collect adverse events and good catch data; analyze the causes and contributing factors; and find ways to prevent future occurrences. MATERIAL AND METHODS: Incident learning consists of a feedback loop which starts with reporting an event, followed by analysis of contributing factors, and culminates in the development of a patient safety work product (PSWP) to prevent recurrence...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047744/we-a-201-01-memorial-introduction
#3
C Marshall
: Chris Marshall: Memorial Introduction Donald Edmonds Herbert Jr., or Don to his colleagues and friends, exemplified the "big tent" vision of medical physics, specializing in Applied Statistics and Dynamical Systems theory. He saw, more clearly than most, that "Making models is the difference between doing science and just fooling around [ref Woodworth, 2004]". Don developed an interest in chemistry at school by "reading a book" - a recurring theme in his story. He was awarded a Westinghouse Science scholarship and attended the Carnegie Institute of Technology (later Carnegie Mellon University) where his interest turned to physics and led to a BS in Physics after transfer to Northwestern University...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047624/su-g-jep3-07-real-time-image-guided-radiation-therapy-for-heterotopic-ossification-in-patients-after-hip-replacement
#4
A Le, S Jiang, R Timmerman, H Choy, A Pompos
PURPOSE: To demonstrate the feasibility of using CBCT in a real-time image guided radiation therapy (IGRT) for single fraction heterotopic ossification (HO) in patients after hip replacement. In this real-time procedure, all steps, from simulation, imaging, planning to treatment delivery, are performed at the treatment unit in one appointment time slot. This work promotes real-time treatment to create a paradigm shift in the single fraction radiation therapy. METHODS: An integrated real-time IGRT for HO was developed and tested for radiation treatment of heterotopic ossification for patient after hip replacement...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047091/we-a-201-02-modern-statistical-modeling
#5
A Niemierko
: Chris Marshall: Memorial Introduction Donald Edmonds Herbert Jr., or Don to his colleagues and friends, exemplified the "big tent" vision of medical physics, specializing in Applied Statistics and Dynamical Systems theory. He saw, more clearly than most, that "Making models is the difference between doing science and just fooling around [ref Woodworth, 2004]". Don developed an interest in chemistry at school by "reading a book" - a recurring theme in his story. He was awarded a Westinghouse Science scholarship and attended the Carnegie Institute of Technology (later Carnegie Mellon University) where his interest turned to physics and led to a BS in Physics after transfer to Northwestern University...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047030/su-g-iep3-05-effects-of-image-receptor-technology-and-dose-reduction-software-on-radiation-dose-estimates-for-fluoroscopically-guided-interventional-fgi-procedures
#6
Z Merritt, J Dave, D Eschelman, C Gonsalves
PURPOSE: To investigate the effects of image receptor technology and dose reduction software on radiation dose estimates for most frequently performed fluoroscopically-guided interventional (FGI) procedures at a tertiary health care center. METHODS: IRB approval was obtained for retrospective analysis of FGI procedures performed in the interventional radiology suites between January-2011 and December-2015. This included procedures performed using image-intensifier (II) based systems which were subsequently replaced, flat-panel-detector (FPD) based systems which were later upgraded with ClarityIQ dose reduction software (Philips Healthcare) and relatively new FPD system already equipped with ClarityIQ...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046987/su-f-p-10-a-web-based-radiation-safety-relational-database-module-for-regulatory-compliance
#7
C Rosen, B Ramsay, S Konerth, D Roller, A Ramsay
PURPOSE: Maintaining compliance with Radioactive Materials Licenses is inherently a time-consuming task requiring focus and attention to detail. Staff tasked with these responsibilities, such as the Radiation Safety Officer and associated personnel must retain disparate records for eventual placement into one or more annual reports. Entering results and records in a relational database using a web browser as the interface, and storing that data in a cloud-based storage site, removes procedural barriers...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046765/su-f-t-49-dosimetry-parameters-and-tps-commissioning-for-the-civasheet-directional-pd-103-brachytherapy-source
#8
M J Rivard
PURPOSE: The CivaSheet is a new LDR Pd-103 brachytherapy device offering directional-radiation for preferentially irradiating malignancies with healthy-tissue sparing. Observations are presented on dosimetric characterization, TPS commissioning, and evaluation of the dosesuperposition- principle for summing individual elements comprising a planar CivaSheet METHODS: The CivaSheet comprises individual sources (CivaDots, 0.05cm thick and 0.25cm diam.) inside a flexible bioabsorbable substrate with a 0...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046561/we-a-201-00-anne-and-donald-herbert-distinguished-lectureship-on-modern-statistical-modeling
#9
Joseph Deasy
: Chris Marshall: Memorial Introduction Donald Edmonds Herbert Jr., or Don to his colleagues and friends, exemplified the "big tent" vision of medical physics, specializing in Applied Statistics and Dynamical Systems theory. He saw, more clearly than most, that "Making models is the difference between doing science and just fooling around [ref Woodworth, 2004]". Don developed an interest in chemistry at school by "reading a book" - a recurring theme in his story. He was awarded a Westinghouse Science scholarship and attended the Carnegie Institute of Technology (later Carnegie Mellon University) where his interest turned to physics and led to a BS in Physics after transfer to Northwestern University...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28043267/-investigation-of-emergency-capacities-for-occupational-hazard-accidents-in-silicon-solar-cell-producing-enterprises
#10
D D Yang, J N Xu, B L Zhu
Objective: To investigate and analyze the influential factors of occupational hazard acci-dents, emergency facilities and emergency management in Silicon solar cell producing enterprises, then to pro-vide scientific strategies. Methods: The methods of occupationally healthy field investigating, inspecting of ven-tilation effectiveness, setup of emergency program and wearing chemical suit were used. Results: The mainly occupational hazard accidents factors in the process of Silicon solar cell producing included poisoning chemi-cals, high temperature, onizing radiation and some workplaces...
November 20, 2016: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/28039011/a-directional-103-pd-brachytherapy-device-dosimetric-characterization-and-practical-aspects-for-clinical-use
#11
Mark J Rivard
PURPOSE: A brachytherapy (BT) device has been developed with shielding to provide directional BT for preferentially irradiating malignancies while sparing healthy tissues. The CivaSheet is a flexible low-dose-rate BT device containing CivaDots with (103)Pd shielded by a thin Au disk. This is the first report of a clinical dosimetric characterization of the CivaSheet device. METHODS AND MATERIALS: Radiation dose distributions near a CivaDot were estimated using the MCNP6 radiation transport code...
December 27, 2016: Brachytherapy
https://www.readbyqxmd.com/read/28024718/patterns-of-dysphagia-and-acute-toxicities-in-patients-with-head-and-neck-cancer-undergoing-helical-imrt%C3%A2-concurrent-chemotherapy
#12
Laura B Moroney, Jennifer Helios, Elizabeth C Ward, Jane Crombie, Leesa F Wockner, Clare L Burns, Ann-Louise Spurgin, Claire Blake, Lizbeth Kenny, Brett G M Hughes
BACKGROUND: There is limited prospective data reporting the extent of treatment related toxicities associated with helical Intensity Modulated Radiotherapy (H-IMRT) for head and neck cancer (HNC). The study aim was to investigate severity, peak incidence and recovery patterns of dysphagia and related toxicities in patients undergoing H-IMRT±chemotherapy to examine when patients are experiencing symptoms requiring supportive clinical care. METHODS: Prospective study of 212 patients undergoing H-IMRT...
January 2017: Oral Oncology
https://www.readbyqxmd.com/read/27993570/radiation-oncology-enters-the-era-of-individualised-medicine
#13
Philip Poortmans, Orit Kaidar-Person, Paul Span
No abstract text is available yet for this article.
December 16, 2016: Lancet Oncology
https://www.readbyqxmd.com/read/27993569/a-genome-based-model-for-adjusting-radiotherapy-dose-gard-a-retrospective-cohort-based-study
#14
Jacob G Scott, Anders Berglund, Michael J Schell, Ivaylo Mihaylov, William J Fulp, Binglin Yue, Eric Welsh, Jimmy J Caudell, Kamran Ahmed, Tobin S Strom, Eric Mellon, Puja Venkat, Peter Johnstone, John Foekens, Jae Lee, Eduardo Moros, William S Dalton, Steven A Eschrich, Howard McLeod, Louis B Harrison, Javier F Torres-Roca
BACKGROUND: Despite its common use in cancer treatment, radiotherapy has not yet entered the era of precision medicine, and there have been no approaches to adjust dose based on biological differences between or within tumours. We aimed to assess whether a patient-specific molecular signature of radiation sensitivity could be used to identify the optimum radiotherapy dose. METHODS: We used the gene-expression-based radiation-sensitivity index and the linear quadratic model to derive the genomic-adjusted radiation dose (GARD)...
December 18, 2016: Lancet Oncology
https://www.readbyqxmd.com/read/27986343/nation-scale-adoption-of-shorter-breast-radiation-therapy-schedules-can-increase-survival-in-resource-constrained-economies-results-from-a-markov-chain-analysis
#15
Atif J Khan, Raza Rafique, Waleed Zafar, Chirag Shah, Bruce G Haffty, Frank Vicini, Arif Jamshed, Yao Zhao
PURPOSE: Hypofractionated whole breast irradiation and accelerated partial breast irradiation (APBI) offer women options for shorter courses of breast radiation therapy. The impact of these shorter schedules on the breast cancer populations of emerging economies with limited radiation therapy resources is unknown. We hypothesized that adoption of these schedules would improve throughput in the system and, by allowing more women access to life-saving treatments, improve patient survival within the system...
February 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27973960/the-accuracy-and-the-safety-of-individualized-3d-printing-screws-insertion-templates-for-cervical-screw-insertion
#16
Ting Deng, Minghui Jiang, Qing Lei, Lihong Cai, Li Chen
STUDY DESIGN: Clinical trial for cervical screw insertion by using individualized 3-dimensional (3D) printing screw insertion templates device. OBJECTIVE: The objective of this study is to evaluate the safety and accuracy of the individualized 3D printing screw insertion template in the cervical spine. MATERIALS AND METHODS: Ten patients who underwent posterior cervical fusion surgery with cervical pedicle screws, laminar screws or lateral mass screws between December 2014 and December 2015 were involved in this study...
December 2016: Comput Assist Surg (Abingdon)
https://www.readbyqxmd.com/read/27960460/optical-torques-on-upconverting-particles-for-intracellular-microrheometry
#17
Paloma Rodríguez-Sevilla, Yuhai Zhang, Nuno de Sousa, Manuel I Marqués, Francisco Sanz-Rodríguez, Daniel Jaque, Xiaogang Liu, Patricia Haro-González
Precise knowledge and control over the orientation of individual upconverting particles is extremely important for full exploiting their capabilities as multifunctional bioprobes for interdisciplinary applications. In this work, we report on how time-resolved, single particle polarized spectroscopy can be used to determine the orientation dynamics of a single upconverting particle when entering into an optical trap. Experimental results have unequivocally evidenced the existence of a unique stable configuration...
December 14, 2016: Nano Letters
https://www.readbyqxmd.com/read/27906943/fluoroscopic-sacroiliac-joint-injection-is-oblique-angulation-really-necessary
#18
Sandeep Khuba, Anil Agarwal, Sujeet Gautam, Sanjay Kumar
BACKGROUND: The conventional technique for sacroiliac (SI) joint injection involves aligning the anterior and posterior aspects of the SI joint under fluoroscopic guidance and then entering the SI joint in the most caudal aspect. OBJECTIVE: We wish to highlight that there is no added advantage to aligning both the anterior and posterior joint lines of the SI joint as it is time consuming, associated with additional radiation exposure, and may make the entry into the posterior SI joint technically more difficult...
November 2016: Pain Physician
https://www.readbyqxmd.com/read/27892590/near-infrared-selective-dynamic-windows-controlled-by-charge-transfer-impedance-at-the-counter-electrode
#19
Praveen Pattathil, Riccardo Scarfiello, Roberto Giannuzzi, Giulia Veramonti, Teresa Sibillano, Antonio Qualtieri, Cinzia Giannini, P Davide Cozzoli, Michele Manca
Recent developments in the exploitation of transparent conductive oxide nanocrystals paved the way to the realization of a new class of electrochemical systems capable of selectively shielding the infrared heat loads carried by sunlight and prospected the blooming of a key enabling technology to be implemented in the next generation of "zero-energy" building envelopes. Here we report the fabrication of a set of electrochromic devices embodying an engineered nanostructured electrode made by high aspect-ratio tungsten oxide nanorods, which allow for selectively and dynamically controlling sunlight transmission over the near-infrared to visible range...
December 8, 2016: Nanoscale
https://www.readbyqxmd.com/read/27869214/irradiance-dependent-uvb-photocarcinogenesis
#20
Cheng-Che E Lan, Ching-Shuang Wu, Shu-Mei Huang, Chin-Han Wu, Hsiao-Chi Lai, Yu-Ting Peng, Pao-Sheng Hou, Hui-Jun Yang, Gwo-Shing Chen
Ultraviolet B (UVB) radiation from the sun may lead to photocarcinogenesis of the skin. Sunscreens were used to protect the skin by reducing UVB irradiance, but sunscreen use did not reduce sunburn episodes. It was shown that UVB-induced erythema depends on surface exposure but not irradiance of UVB. We previously showed that irradiance plays a critical role in UVB-induced cell differentiation. This study investigated the impact of irradiance on UVB-induced photocarcinogenesis. For hairless mice receiving equivalent exposure of UVB radiation, the low irradiance (LI) UVB treated mice showed more rapid tumor development, larger tumor burden, and more keratinocytes harboring mutant p53 in the epidermis as compared to their high irradiance (HI) UVB treated counterpart...
November 21, 2016: Scientific Reports
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