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https://www.readbyqxmd.com/read/29146760/blepharitis-as-an-early-sign-of-metabolic-syndrome-a-nationwide-population-based-study
#1
Chia-Yi Lee, Hung-Chi Chen, Hui-Wen Lin, Jing-Yang Huang, Shih-Chun Chao, Chao-Bin Yeh, Hung-Yu Lin, Shun-Fa Yang
BACKGROUND: To investigate the relationship between blepharitis and metabolic syndrome (MetS) by using the Longitudinal Health Insurance Database (LHID) of Taiwan. METHODS: This retrospective cohort study was conducted using data collected from the LHID for the period from 2009 to 2013. This study enrolled patients who received a diagnosis of blepharitis according to the International Classification of Diseases, Ninth Revision, diagnostic code. The exclusion criteria were legal blindness, eyeball removal, ocular tumours prior to the diagnosis of blepharitis, and patients diagnosed with blepharitis and initiated antibiotic treatment concurrently...
November 16, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29138069/traumatic-fractures-of-the-cervical-spine-analysis-of-changes-in-incidence-etiology-concurrent-injuries-and-complications-among-488-262-patients-from-2005-2013
#2
Peter G Passias, Gregory W Poorman, Frank A Segreto, Cyrus M Jalai, Samantha R Horn, Cole A Bortz, Dennis Vasquez-Montes, Bassel G Diebo, Shaleen Vira, Olivia J Bono, Rafael De La Garza-Ramos, John Y Moon, Charles Wang, Brandon P Hirsch, Peter L Zhou, Michael Gerling, Heiko Koller, Virginie Lafage
OBJECTIVE: The etiologies and epidemiology of traumatic cervical spine fracture have not been described with sufficient power or recency. Our goal is to describe demographics, incidence, etiology, spinal cord injuries (SCIs), concurrent injuries, treatments, and complications of traumatic cervical spine fractures. METHODS: Retrospective review of the Nationwide Inpatient Sample. ICD-9 E-Codes identified trauma cases from 2005-2013. Patients with cervical fracture were isolated...
November 11, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29135667/nationwide-analysis-of-femoral-neck-fractures-in-elderly-patients-a-receding-tide
#3
Derek G Ju, Sean S Rajaee, James Mirocha, Carol A Lin, Charles N Moon
BACKGROUND: Geriatric femoral neck fractures are associated with substantial morbidity and medical cost. We evaluated the incidence and management trends of femoral neck fractures in recent years in the U.S. METHODS: Patient data from 2003 through 2013 were obtained from the Nationwide Inpatient Sample database. Femoral neck fractures in patients ≥65 years old were identified and grouped using the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) procedure codes for internal fixation, hemiarthroplasty, or total hip arthroplasty (THA)...
November 15, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29124851/lower-risk-of-pelvic-metalware-infection-with-operative-repair-of-concurrent-bladder-rupture
#4
Henry H-I Yao, Max Esser, Jeremy Grummet, Chris Atkins, Peter Royce, Uri Hanegbi
BACKGROUND: Patients with traumatic bladder rupture frequently have associated pelvic fracture. With increasing numbers of pelvic fractures fixed internally, there are concerns that conservative management of bladder rupture may increase the risk of pelvic metalware infection. This study aims to determine if operative repair of bladder rupture in comparison to conservative management with catheter drainage alone is associated with a lower rate of infection of internal fixation device for concurrent pelvic fracture...
November 9, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29108478/evaluation-of-a-computer-based-prompting-intervention-to-improve-essay-writing-in-undergraduates-with-cognitive-impairment-after-acquired-brain-injury
#5
Alexander K Ledbetter, McKay Moore Sohlberg, Stephen F Fickas, Mark A Horney, Kent McIntosh
This study evaluated a computer-based prompting intervention for improving expository essay writing after acquired brain injury (ABI). Four undergraduate participants aged 18-21 with mild-moderate ABI and impaired fluid cognition at least 6 months post-injury reported difficulty with the writing process after injury. The study employed a non-concurrent multiple probe across participants, in a single-case design. Outcome measures included essay quality scores and number of revisions to writing counted then coded by type using a revision taxonomy...
November 6, 2017: Neuropsychological Rehabilitation
https://www.readbyqxmd.com/read/29105982/trends-in-the-diffusion-of-robotic-surgery-a-retrospective-observational-study
#6
Hani J Marcus, Archie Hughes-Hallett, Christopher J Payne, Thomas P Cundy, Dipankar Nandi, Guang-Zhong Yang, Ara Darzi
BACKGROUND: Recent studies have suggested that the use of robotic surgery for prostatectomy has been increasing, but characterization of the diffusion of robotic surgery in other procedures has not been available. METHODS: Data were analysed for the years 2006-2014 using hospital episode statistics (HES), a database of all admissions to National Health Service (NHS) hospitals in England. OPCS codes were used to determine the annual number of prostatectomy, partial nephrectomy, and total abdominal hysterectomy procedures...
November 6, 2017: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://www.readbyqxmd.com/read/29083303/deep-transcriptome-annotation%C3%A2-enables-the-discovery-and-functional-characterization-of-cryptic-small-proteins
#7
Sondos Samandi, Annie V Roy, Vivian Delcourt, Jean-François Lucier, Jules Gagnon, Maxime C Beaudoin, Benoît Vanderperre, Marc-André Breton, Julie Motard, Jean-François Jacques, Mylène Brunelle, Isabelle Gagnon-Arsenault, Isabelle Fournier, Aïda Ouangraoua, Darel J Hunting, Alan A Cohen, Christian R Landry, Michelle S Scott, Xavier Roucou
Recent functional, proteomic and ribosome profiling studies in eukaryotes have concurrently demonstrated the translation of alternative open reading frames (altORFs) in addition to annotated protein coding sequences (CDSs). We show that a large number of small proteins could in fact be coded by these altORFs. The putative alternative proteins translated from altORFs have orthologs in many species and contain functional domains. Evolutionary analyses indicate that altORFs often show more extreme conservation patterns than their CDSs...
October 30, 2017: ELife
https://www.readbyqxmd.com/read/29083254/interprofessional-practice-in-different-patient-care-settings-a-qualitative-exploration
#8
Deborah DiazGranados, Alan W Dow, Nital Appelbaum, Paul E Mazmanian, Sheldon M Retchin
Increasing interprofessional practice is seen as a path to improved quality, decreased cost, and enhanced patient experience. However, little is known about how context shapes interprofessional work and how interventions should be crafted to account for a specific setting of interprofessional practice. To better understand, how the work of interprofessional practice differs across patient care settings we sought to understand the social processes found in varying work contexts to better understand how care is provided...
October 30, 2017: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/29082797/adaptive-equipment-use-by-people-with-motor-neuron-disease-in-australia-a-prospective-observational-consecutive-cohort-study
#9
Karol A Connors, Lisa M Mahony, Prue Morgan
PURPOSE: People with motor neuron sisease require adaptive equipment to enhance life quality. This study aimed to examine total and concurrent equipment items prescribed with phenotype consideration. METHODS: A prospective, observational consecutive cohort study was undertaken. Data regarding Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised, phenotype, symptom onset and Functional Independence Measure (inpatients only) was recorded. Equipment utilized was coded by therapist as: speech devices; transfer devices; mobility devices (including power wheelchairs); orthoses; activities of daily living equipment; assisted technology and home modification equipment...
October 28, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29079609/investigation-of-the-international-comparability-of-population-based-routine-hospital-data-set-derived-comorbidity-scores-for-patients-with-lung-cancer
#10
Margreet Lüchtenborg, Eva J A Morris, Daniela Tataru, Victoria H Coupland, Andrew Smith, Roger L Milne, Luc Te Marvelde, Deborah Baker, Jane Young, Donna Turner, Diane Nishri, Craig Earle, Lorraine Shack, Anna Gavin, Deirdre Fitzpatrick, Conan Donnelly, Yulan Lin, Bjorn Moller, David H Brewster, Andrew Deas, Dyfed W Huws, Ceri White, Janet Warlow, Jem Rashbass, Michael D Peake
INTRODUCTION: The International Cancer Benchmarking Partnership (ICBP) identified significant international differences in lung cancer survival. Differing levels of comorbid disease across ICBP countries has been suggested as a potential explanation of this variation but, to date, no studies have quantified its impact. This study investigated whether comparable, robust comorbidity scores can be derived from the different routine population-based cancer data sets available in the ICBP jurisdictions and, if so, use them to quantify international variation in comorbidity and determine its influence on outcome...
October 27, 2017: Thorax
https://www.readbyqxmd.com/read/29076928/therapeutic-mastoidectomy-does-not-increase-postoperative-complications-in-the-management-of-the-chronic-ear
#11
Matthew A Shew, Thomas Muelleman, Mark Villwock, Robert J Muelleman, Kevin Sykes, Hinrich Staecker, James L Lin
OBJECTIVE: Tympanoplasty with or without concurrent therapeutic mastoidectomy is a controversial topic in the management of chronic ear disease. We sought to describe whether there is a significant difference in postoperative complications. STUDY DESIGN: Retrospective cohort study. SETTING: American College of Surgeons National Surgical Quality Improvement Program public files. PATIENTS: Current procedural terminology codes were used to identify patients with chronic ear disease undergoing tympanoplasty ± concurrent mastoidectomy in the 2011 to 14 American College of Surgeons National Surgical Quality Improvement Program files...
October 26, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29070961/the-trajectory-of-concurrent-motor-and-vocal-behaviors-over-the-transition-to-crawling-in-infancy
#12
Sarah E Berger, Marian Cunsolo, Mariam Ali, Jana M Iverson
To document the trajectory of motor and vocal behaviors in real and developmental time, researchers observed infants at each of 4 biweekly naturalistic play sessions over the transition to crawling. An exhaustive and mutually exclusive coding scheme documented every vocalization and posture. Odds ratios of the likelihood of a given posture-vocalization dyad revealed that vocalization and crawling were significantly unlikely to co-occur at the session marking the onset of crawling. Infants' allocation of attention over the transition to crawling prompted behavioral trade-offs...
September 2017: Infancy: the Official Journal of the International Society on Infant Studies
https://www.readbyqxmd.com/read/29067134/attention-is-shaped-by-semantic-level-of-event-structure-during-speech-comprehension-an-electroencephalogram-study
#13
Xiaoqing Li, Yuping Zhang, Lin Li, Haiyan Zhao, Xiufang Du
The present electroencephalogram study used an attention probe paradigm to investigate how semantic and acoustic structures constrain temporal attention during speech comprehension. Spoken sentences were used as stimuli, with each one containing a four-character critical phrase, of which the third character was the target character. We manipulated not only the semantic relationship between the target character and the immediately preceding two characters, but also the presence/absence of a pitch accent on the first character...
October 2017: Cognitive Neurodynamics
https://www.readbyqxmd.com/read/29058936/mothers-dispositional-distress-reactivity-as-a-predictor-of-maternal-support-following-momentary-fluctuations-in-children-s-aversive-behavior
#14
Niyantri Ravindran, Nancy L McElwain, Daniel Berry, Laurie Kramer
Given that maternal support promotes healthy social and emotional development in early childhood, it is important to understand the predictors of such support, especially during emotional challenges. In this study, mothers' dispositional distress reactivity (i.e., the tendency toward experiencing distress in response to children's negative emotions and behavior) was assessed as a predictor of maternal support in a given moment when children showed within-person fluctuations in aversive behavior (i.e., negative affect and disruptive behaviors) in concurrent and prior moments...
October 23, 2017: Developmental Psychology
https://www.readbyqxmd.com/read/29054293/corticostriatal-plasticity-neuronal-ensembles-and-regulation-of-drug-seeking-behavior
#15
Ana-Clara Bobadilla, Jasper A Heinsbroek, Cassandra D Gipson, William C Griffin, Christie D Fowler, Paul J Kenny, Peter W Kalivas
The idea that interconnected neuronal ensembles code for specific behaviors has been around for decades; however, recent technical improvements allow studying these networks and their causal role in initiating and maintaining behavior. In particular, the role of ensembles in drug-seeking behaviors in the context of addiction is being actively investigated. Concurrent with breakthroughs in quantifying ensembles, research has identified a role for synaptic glutamate spillover during relapse. In particular, the transient relapse-associated changes in glutamatergic synapses on accumbens neurons, as well as in adjacent astroglia and extracellular matrix, are key elements of the synaptic plasticity encoded by drug use and the metaplasticity induced by drug-associated cues that precipitate drug-seeking behaviors...
2017: Progress in Brain Research
https://www.readbyqxmd.com/read/29052036/rapidly-increasing-incidence-in-scoliosis-surgery-over-14%C3%A2-years-in-a-nationwide-sample
#16
Johan von Heideken, Maura D Iversen, Paul Gerdhem
PURPOSE: Severe scoliosis is primarily managed with surgery. This cohort study describes the incidence of surgically treated scoliosis among Swedish youth and young adults, stratified by age, sex, scoliosis type, and surgical approach and identifies changes in incidence rate and hospital length of stay (LOS), infections requiring re-surgery and mortality within 90 days. METHODS: Swedish youth, 0-21 years, (n = 3062) with a diagnostic code for scoliosis and spine surgery between 2000 and 2013 were selected from the National Patient Register...
October 19, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29046423/the-intrinsic-physiology-of-inhibitory-neurons-changes-over-auditory-development
#17
Briana J Carroll, Richard Bertram, Richard L Hyson
During auditory development, changes in membrane properties promote the ability of excitatory neurons in the brainstem to code aspects of sound, including the level and timing of a stimulus. Some of these changes coincide with hearing onset, suggesting that sound-driven neural activity produces developmental plasticity of ion channel expression. While it is known that the coding properties of excitatory neurons are modulated by inhibition in the mature system, it is unknown whether there are also developmental changes in the membrane properties of brainstem inhibitory neurons...
October 18, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29016431/incidence-of-congenital-spinal-abnormalities-among-pediatric-patients-and-their-association-with-scoliosis-and-systemic-anomalies
#18
Peter G Passias, Gregory W Poorman, Cyrus M Jalai, Bassel G Diebo, Shaleen Vira, Samantha R Horn, Joseph F Baker, Kartik Shenoy, Saqib Hasan, John Buza, Wesley Bronson, Justin C Paul, Ian Kaye, Norah A Foster, Ryan T Cassilly, Jonathan H Oren, Ronald Moskovich, Breton Line, Cheongeun Oh, Shay Bess, Virginie LaFage, Thomas J Errico
BACKGROUND: Congenital abnormalities when present, according to VACTERL theory, occur nonrandomly with other congenital anomalies. This study estimates the prevalence of congenital spinal anomalies, and their concurrence with other systemic anomalies. METHODS: A retrospective cohort analysis on Health care Cost and Utilization Project's Kids Inpatient Database (KID), years 2000, 2003, 2006, 2009 was performed. ICD-9 coding identified congenital anomalies of the spine and other body systems...
October 9, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28985880/trends-in-parastomal-hernia-repair-in-the-united-states-a-14-y-review
#19
Thomas Gavigan, Nigel Rozario, Brent Matthews, Caroline Reinke
BACKGROUND: Parastomal hernia is the most common complication after stoma creation. Parastomal hernias can create significant morbidity, including patient discomfort, small bowel obstruction, and need for emergency surgery. We examined national trends in parastomal hernia repair (PHR) including annual frequency of procedure, patient characteristics, and same-admission complications. MATERIALS AND METHODS: The 1998-2011 Nationwide Inpatient Sample was used to identify patients who underwent a PHR (International Classification of Disease, Ninth Edition, Procedure Code [ICD-9 PR] 46...
October 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28977945/genetic-polymorphisms-of-long-non-coding-rna-gas5-predict-platinum-based-concurrent-chemoradiotherapy-response-in-nasopharyngeal-carcinoma-patients
#20
Zhen Guo, Youhong Wang, Yu Zhao, Yi Jin, Liang An, Bin Wu, Zhaoqian Liu, Xiaoping Chen, Honghao Zhou, Hui Wang, Wei Zhang
LncRNA GAS5 plays a tumor suppressive role in a variety of human cancers and promises to be a novel diagnostic biomarker, therapy target, as well as prognostic biomarker. However, the role of GAS5 in nasopharyngeal carcinoma (NPC) remains elusive. The objective of the present study was to evaluate the effect of single nucleotide polymorphisms (SNPs) in GAS5 on treatment efficacy and toxicity in NPC patients receiving chemoradiotherapy. Three potentially functional SNPs of GAS5 were genotyped in 267 NPC patients and validated in another 238 NPC patients treated with chemoradiotherapy from southern China...
September 22, 2017: Oncotarget
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