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Acellular dermal matrix

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https://www.readbyqxmd.com/read/28210552/capsular-contracture-in-implant-based-breast-reconstruction-the-effect-of-porcine-acellular-dermal-matrix
#1
Alessia M Lardi, Mark Ho-Asjoe, Klaus Junge, Jian Farhadi
BACKGROUND: Irradiation of implant-based breast reconstructions (BR) is known to increase capsular contracture (CC) rates on average by 4-fold over non-irradiated reconstructions. The use of acellular dermal matrix (ADM) has been associated with lower CC rates in non-irradiated reconstructions (0-3%). Experimental and clinical studies suggest that ADM may also reduce CC rates in irradiated breasts. The aim of this study was to evaluate CC rates in non-irradiated and irradiated one- and two-stage BRs performed with the assistance of porcine ADM (PADM)...
February 2017: Gland Surgery
https://www.readbyqxmd.com/read/28204936/impact-of-acellular-dermal-matrix-adm-use-under-mastectomy-flap-necrosis-on-perioperative-outcomes-of-prosthetic-breast-reconstruction
#2
So Young Kim, Sa Ik Bang
BACKGROUND: There is conflicting data on the potential necrotic complications of acellular dermal matrix (ADM) use in breast reconstruction, and most studies focus on mastectomy flap necrosis as an outcome measure associated with ADM use. The aim of this study was to examine cases with necrotic complications with and without the use of ADM and to investigate whether ADM affected perioperative outcomes in cases with necrotic complications. METHODS: Patients who experienced mastectomy flap necrosis following mastectomy with tissue expander placement between January 2009 and March 2015 were retrospectively reviewed...
February 15, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28203509/the-breastrial-stage-ii-adm-breast-reconstruction-outcomes-from-definitive-reconstruction-to-3-months-postoperative
#3
Shaun D Mendenhall, Layla A Anderson, Jian Ying, Kenneth M Boucher, Leigh A Neumayer, Jayant P Agarwal
BACKGROUND: The Breast Reconstruction Evaluation of Acellular Dermal Matrix as a Sling Trial is a prospective randomized trial comparing outcomes of tissue expander breast reconstruction using either AlloDerm or DermaMatrix. The trial was divided into 3 outcome stages; this study reports stage II outcomes, which are those from the time of definitive reconstruction to 3 months postoperative. METHODS: A randomized trial was conducted to compare complication rates between AlloDerm and DermaMatrix groups...
January 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28194290/latissimus-dorsi-tendon-transfer-with-graftjacket%C3%A2-augmentation-to-increase-tendon-length-for-an-irreparable-rotator-cuff-tear
#4
John G Skedros, Tanner R Henrie
Massive irreparable rotator cuff tears can be reconstructed with latissimus dorsi tendon transfers (LDTT). Although uncommon, the natural length of the latissimus dorsi tendon (LDT) could be insufficient for transfer even after adequate soft tissue releases. Descriptions of cases where grafts were needed to lengthen the LDT are therefore rare. We located only two reports of the use of an acellular dermal matrix to increase effective tendon length in tendon transfers about the shoulder: (1) GraftJacket patch for a pectoralis major tendon reconstruction and (2) ArthroFlex® patch for LDTT...
2017: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/28190760/a-guide-to-prepectoral-breast-reconstruction-a%C3%A2-new-dimension-to-implant-based-breast-reconstruction
#5
REVIEW
Raghavan Vidya, Fahad Mujtaba Iqbal
Acellular dermal matrix has revolutionized implant-based breast reconstruction. Breast reconstruction has evolved from the traditional submuscular to the new prepectoral implant based (also known as muscle-sparing) reconstruction. The new technique is emerging as a highly popular surgery owing to its more minimal approach. We conducted a narrative review to guide prepectoral breast reconstruction, highlighting the technique, the need for appropriate patient selection, and areas for further research. We show that prepectoral breast reconstruction is safe, feasible, and has excellent short-term outcomes (cosmesis and patient satisfaction)...
January 9, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28141953/interposition-dermal-matrix-xenografts
#6
Julie A Neumann, Miltiadis H Zgonis, Kathleen D Rickert, Kendall E Bradley, Thomas J Kremen, Blake R Boggess, Alison P Toth
BACKGROUND: Management of massive rotator cuff tears in shoulders without glenohumeral arthritis remains problematic for surgeons. Repairs of massive rotator cuff tears have failure rates of 20% to 94% at 1 to 2 years postoperatively as demonstrated with arthrography, ultrasound, and magnetic resonance imaging. Additionally, inconsistent outcomes have been reported with debridement alone of massive rotator cuff tears, and limitations have been seen with other current methods of operative intervention, including arthroplasty and tendon transfers...
January 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28129211/a-new-form-of-artificial-skin-to-promote-permanent-wound-coverage-a-preliminary-report
#7
Hsian-Jenn Wang, Lin-Gwei Wei, Chi-Hsien Wang, Ya-Chen Cheng, Junn-Liang Chang, Tai-Li Tsou, Chih-Hung Ku, Chun-Chang Li, Wen-Kuan Chiu, Chieh-Feng Chen
BACKGROUND: Although tendon-exposed or bone-exposed wounds can be resurfaced with flaps, such surgeries may not be feasible in patients with poor general or local conditions. Biosynthetic artificial skin is an alternative for critical wound coverage. We designed a new artificial skin bilayer to close difficult wounds permanently. AIM AND OBJECTIVES: This study compares incorporation and wound contraction between silicone acellular porcine dermis (SAPD) and the Integra graft (Integra Life Sciences Corp...
January 27, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28121875/advanced-imaging-techniques-for-investigation-of-acellular-dermal-matrix-biointegration
#8
Brent R DeGeorge, Bo Ning, Lisa S Salopek, Angela Pineros-Fernandez, George T Rodeheaver, Shayn Peirce-Cottler, Song Hu, Patrick S Cottler, Christopher A Campbell
BACKGROUND: Biointegration, a concept involving a dynamic interplay among three processes-inflammation, cellular infiltration, and angiogenesis-is key to understanding the interaction between acellular dermal matrices and the host. The current standard for evaluating acellular dermal matrix biointegration involves histologic analysis at fixed time points; however, the authors' approach uses advanced imaging techniques to serially assess biointegration in real time. METHODS: The authors have adapted two advanced imaging techniques-two-photon microscopy and photoacoustic microscopy-to investigate biointegration in a murine deepithelialized dorsal skin-fold window chamber model, specifically engineered to recapitulate the host microenvironment of acellular dermal matrix-assisted breast reconstruction...
February 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28119764/relevant-in-vitro-predictors-of-human-acellular-dermal-matrix-associated-inflammation-and-capsule-formation-in-a-nonhuman-primate-subcutaneous-tissue-expander-model
#9
Maryellen Sandor, Patrick Leamy, Pearl Assan, Amardeep Hoonjan, Li-Ting Huang, Marianne Edwards, Wenqi Zuo, Hui Li, Hui Xu
Objective: Benchtop methods were evaluated for preclinical inflammation/capsule formation correlation following implantation of human acellular dermal matrices. Methods: Dermal matrices were compared with native dermis for structure (histology, scanning electron microscopy), collagen solubility (hydroxyproline), enzymatic susceptibility (collagenase), and thermal stability (differential scanning calorimetry). Results were compared with implantation outcomes in a primate tissue expander model. Results: Native dermis, electron beam-sterilized, and freeze-dried human acellular dermal matrices had equivalent morphology, acid-soluble collagen (60...
2017: Eplasty
https://www.readbyqxmd.com/read/28106696/use-of-acellular-dermal-matrix-in-treatment-of-congenital-muscular-torticollis-in-patients-over-eight-years-of-age
#10
Hyung Min Hahn, Kyung Hoon Cook, Il Jae Lee, Dong Ha Park, Myong Chul Park
BACKGROUND: Treatment for neglected or recurred congenital muscular torticollis should be differentiated from primary patients due to the long-standing adjacent tissue contracture. The aim of this study was to evaluate the effect of acellular dermal matrix (ADM) on surgery of recurred and neglected patients of congenital muscular torticollis. METHODS: Forty-nine patients were included in the study. All patients underwent resection at the distal end of the sternocleidomastoid muscle...
January 18, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28068842/tibialis-anterior-tendon-reconstruction-using-augmented-half-thickness-tendon-segment-transposition
#11
Christopher W Reb, James F Stenson, Joseph N Daniel
: Tibialis anterior tendon rupture causes substantial morbidity. The present study describes the outcomes of augmented, half-thickness tibialis anterior tendon segment transposition, a novel reconstruction technique. This was an institutional review board-approved retrospective review of 3 patients with surgically treated attritional distal rupture with 1-year follow-up. The postdebridement tendon defect prohibited primary repair and was managed by distal transposition of a half-thickness healthy segment...
January 1, 2017: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/28052837/nail-bed-reconstruction-using-single-layer-bovine-acellular-dermal-matrix
#12
REVIEW
David K Fiedler, Justin E Barrett, Gary M Lourie
Traumatic nail bed injuries to the hand are a common problem for hand surgeons. Whereas the majority of those are treated with primary repair, the remainder present significant surgical challenges to address residual soft tissue defects. In this article, we present our approach to treating injuries to the fingertips utilizing single-layer bovine acellular dermal matrix grafts.
January 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28051266/one-stage-breast-reconstruction-techniques-in-elderly-patients-to-preserve-quality-of-life
#13
M Maruccia, M Mazzocchi, L A Dessy, M G Onesti
OBJECTIVE: The aim of this study was to review one-stage breast reconstruction techniques performed in elderly patients at our institution to identify the criteria of selection of each in terms of outcomes and quality of life. PATIENTS AND METHODS: Patients older than 65 years who underwent one-stage breast reconstruction between January 2004 and July 2014 at our hospital were included. Patients and procedure-related data were collected from the medical records...
December 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28043296/-meta-analysis-on-the-clinical-effects-of-allogenic-acellular-dermal-matrix-treatment-for-diabetic-foot-ulcer
#14
C L Xue, Z C Hu, Z X Yang, X J Li
Objective: To analyze the clinical effects of allogenic acellular dermal matrix (ADM) treatment for diabetic foot ulcer (DFU) with meta-analysis. Methods: Databases including PubMed, Cochrance Library, Embase, and OVID EBM Reviews were searched using key words " diabetic foot, diabetic ulcer, diabetic wound, acellular dermal matrix, acellular dermal regenerative tissue matrix, acellular regenerative tissue matrix, AlloDerm, SureDerm, KaroDerm, Graftjacket, Hyalomatrix PA, and Hyalograft 3D" , and Chinese Biological Abstracts, Chinese Journals Full-text Database, VIP Database, and Wanfang Database were searched using key words in Chinese version ",,," to obtain the published trials of allogenic ADM treatment for DFU from January 1990 to July 2015, and then meta-analysis was used to analyze the trials...
December 20, 2016: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28032164/innovative-management-of-implant-exposure-in-adm-implant-based-breast-reconstruction-with-negative-pressure-wound-therapy
#15
Antonello Accurso, Nicola Rocco, Giuseppe Accardo, Paola Reale, Carmela Salerno, Edi Mattera, Francesco D'Andrea
INTRODUCTION: One-stage implant-based breast reconstruction has been recently improved by the introduction of biological [acellular dermal matrix (ADM)] and synthetic meshes. Advantages of ADMs in implant-based breast reconstruction derive from the expansion of the space available for the direct positioning of an implant, but their use could be associated with several complications. Although the majority of complications can be easily managed, mistakes in dealing with the first clinical signs of a potential adverse event can lead to implant loss...
December 28, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28032163/transition-from-round-to-shaped-implants-in-immediate-breast-reconstruction-our-preferred-approach-and-clinical-outcomes
#16
Thomas A Imahiyerobo, Kevin H Small, Robyn Sackeyfio, Hannah Hoffman, Mia Talmor
BACKGROUND: Smooth, round, silicone implants predominate device-based breast reconstruction in the USA; despite their prevalence, complications can include bottoming out, superior contour deformity, rippling, and/or lateral malposition. This complication profile increases the need for revision surgery and subsequent patient dissatisfaction. With the resurgence of shaped, textured, silicone implants in the USA, we report the senior author's success with these devices and outline a strategy to optimize outcomes in breast reconstruction surgery...
December 28, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28027223/staged-suprapectoral-expander-implant-reconstruction-without-acellular-dermal-matrix-following-nipple-sparing-mastectomy
#17
Arthur H Salibian, Jay K Harness, Donald S Mowlds
BACKGROUND: Since the introduction of nipple-sparing mastectomy as an oncologically safe procedure for the treatment of breast cancer, reconstructive efforts for immediate staged expander/implant reconstruction have focused on submuscular implantation with or without acellular dermal matrix. Suprapectoral reconstruction without acellular dermal matrix has received little attention in the reconstructive literature of nipple-sparing mastectomy. METHODS: Between 2005 and 2015, 155 patients (250 breasts) underwent nipple-sparing mastectomy with prepectoral staged expander/implant reconstruction using thick mastectomy skin flaps without acellular dermal matrix...
January 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28012977/two-stage-implant-based-breast-reconstruction-compared-with-immediate-one-stage-implant-based-breast-reconstruction-augmented-with-an-acellular-dermal-matrix-an-open-label-phase-4-multicentre-randomised-controlled-trial
#18
Rieky E G Dikmans, Vera L Negenborn, Mark-Bram Bouman, Hay A H Winters, Jos W R Twisk, P Quinten Ruhé, Marc A M Mureau, Jan Maerten Smit, Stefania Tuinder, Yassir Eltahir, Nicole A Posch, Josephina M van Steveninck-Barends, Marleen A Meesters-Caberg, René R W J van der Hulst, Marco J P F Ritt, Margriet G Mullender
BACKGROUND: The evidence justifying the use of acellular dermal matrices (ADMs) in implant-based breast reconstruction (IBBR) is limited. We did a prospective randomised trial to compare the safety of IBBR with an ADM immediately after mastectomy with that of two-stage IBBR. METHODS: We did an open-label, randomised, controlled trial in eight hospitals in the Netherlands. Eligible women were older than 18 years with breast carcinoma or a gene mutation linked with breast cancer who intended to undergo skin-sparing mastectomy and immediate IBBR...
December 21, 2016: Lancet Oncology
https://www.readbyqxmd.com/read/27997450/acellular-dermal-matrix-as-an-adjunct-material-in-cleft-le-fort-i-osteotomies
#19
Srinivas M Susarla, Zoe M MacIsaac, Edward Swanson, Edward Davidson, Anand Kumar
PURPOSE: To evaluate the use of acellular dermal matrix in the management of nasal lining deficiency at the time of Le Fort I osteotomy. METHODS: This was a retrospective cohort study of patients with residual/recurrent oronasal fistulae who underwent Le Fort I osteotomy. In instances where there was an inadequate volume of nasal mucosa for tension-free closure or for defects >1 cm in width, the acellular dermal matrix was used for augmentation. Demographic and cleft-related factors were recorded...
January 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27993696/long-term-outcomes-after-abdominal-wall-reconstruction-with-acellular-dermal-matrix
#20
Patrick B Garvey, Salvatore A Giordano, Donald P Baumann, Jun Liu, Charles E Butler
BACKGROUND: Long-term outcomes data for hernia recurrence rates after abdominal wall reconstruction (AWR) with acellular dermal matrix (ADM) are lacking. The aim of this study was to assess the long-term durability of AWR using ADM. STUDY DESIGN: We studied patients who underwent AWR with ADM at a single center in 2005 to 2015 with a minimum follow-up of 36 months. Hernia recurrence was the primary end point and surgical site occurrence (SSO) was a secondary end point...
December 18, 2016: Journal of the American College of Surgeons
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