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https://www.readbyqxmd.com/read/28224159/rice-bran-constituents-immunomodulatory-and-therapeutic-activities
#1
REVIEW
Ho-Young Park, Kwang-Won Lee, Hee-Don Choi
Rice bran, one of the most abundant and valuable byproducts produced during the rice milling process, is of steadily growing interest in recent years due to its potential health benefits. Evidence is rapidly accumulating for the beneficial effects of nutraceuticals. However, the potential benefits of rice bran are found in several of its bioactive ingredients including oils, polysaccharides, proteins, and micronutrients. In addition, a significant advantage of rice bran is that it contains more than 100 antioxidants and several categories of bioactive phytonutrients, such as polyphenols, phytosterols, tocotrienols, γ-oryzanol, B vitamins, minerals, and trace minerals...
February 22, 2017: Food & Function
https://www.readbyqxmd.com/read/28202018/de-novo-biosynthesis-of-pterostilbene-in-an-escherichia-coli-strain-using-a-new-resveratrol-o-methyltransferase-from-arabidopsis
#2
Kyung Taek Heo, Sun-Young Kang, Young-Soo Hong
BACKGROUND: Pterostilbene, a structural analog of resveratrol, has higher oral bioavailability and bioactivity than that of the parent compound; but is far less abundant in natural sources. Thus, to efficiently obtain this bioactive resveratrol analog, it is necessary to develop new bioproduction systems. RESULTS: We identified a resveratrol O-methyltransferase (ROMT) function from a multifunctional caffeic acid O-methyltransferase (COMT) originating from Arabidopsis, which catalyzes the transfer of a methyl group to resveratrol resulting in pterostilbene production...
February 15, 2017: Microbial Cell Factories
https://www.readbyqxmd.com/read/28091970/comparison-of-two-adsorbent-based-de-bittering-procedures-for-neem-azadirachta-indica-a-juss-tea-effect-on-polyphenols-anti-oxidant-capacity-color-and-volatile-profile
#3
Abhinandya Datta, Ingolf U Grün, Misha T Kwasniewski, Lakdas N Fernando
Bitterness reduction, especially of foods and beverages containing phytonutrients, is one of the biggest challenges in the food industry because bitterness has a deleterious effect on the taste profile of foods and beverages. Neem (Azadirachta indica A. Juss) is a medicinal tree, indigenous to the Indian-subcontinent, whose medicinal properties have led to it being heralded as the tree which is the "panacea for all diseases". However, neem leaf is extremely bitter, in large part due to its limonoid content, making it unpalatable...
January 14, 2017: Plant Foods for Human Nutrition
https://www.readbyqxmd.com/read/28074411/biomass-and-terpenoids-produced-by-mutant-strains-of-arthrospira-under-low-temperature-and-light-conditions
#4
Jian Guan, Songdong Shen, Hao Wu, Xin Liu, Weijie Shen, Yuan He, R Duan
The filamentous Cyanobacterium Arthrospira is commercially produced and is a functional, high-value, health food. We identified 5 low temperature and low light intensity tolerant strains of Arthrospira sp. (GMPA1, GMPA7, GMPB1, GMPC1, and GMPC3) using ethyl methanesulfonate mutagenesis and low temperature screening. The 5 Arthrospira strains grew rapidly below 14 °C, 43.75 μmol photons m(-2) s(-1) and performed breed conservation at 2.5 °C, 8.75 μmol photons m(-2) s(-1). We used morphological identification and molecular genetic analysis to identify GMPA1, GMPA7, GMPB1 and GMPC1 as Arthrospira platensis, while GMPC3 was identified as Arthrospira maxima...
February 2017: World Journal of Microbiology & Biotechnology
https://www.readbyqxmd.com/read/28040679/morphological-observation-rna-seq-quantification-and-expression-profiling-novel-insight-into-grafting-responsive-carotenoid-biosynthesis-in-watermelon-grafted-onto-pumpkin-rootstock
#5
Guang Liu, Xingping Yang, Jinhua Xu, Man Zhang, Qian Hou, Lingli Zhu, Ying Huang, Aisheng Xiong
Watermelon is an important and economical horticultural crop in China, where ~20% of the plants are grafted. The development of grafted watermelon fruit involves a diverse range of gene interactions that results in dynamic changes in fruit. However, the molecular mechanisms underlying grafting-induced fruit quality change are unclear. In the present study, we measured the lycopene content by high-performance liquid chromatography and used RNA-Seq (quantification) to perform a genome-wide transcript analysis of fruits from watermelon grafted onto pumpkin rootstock (pumpkin-grafted watermelon, PGW), self-grafted watermelon (SGW), and non-grafted watermelon (NGW)...
December 30, 2016: Acta Biochimica et Biophysica Sinica
https://www.readbyqxmd.com/read/28005447/gynostemma-pentaphyllum-ethanolic-extract-protects-against-memory-deficits-in-an-mptp-lesioned-mouse-model-of-parkinson-s-disease-treated-with-l-dopa
#6
Kyung Sook Kim, Ting Ting Zhao, Keon Sung Shin, Hyun Jin Park, Yoon Jeong Cho, Kyung Eun Lee, Seung Hwan Kim, Myung Koo Lee
This study investigated the effects of ethanol extract from Gynostemma pentaphyllum (GP-EX) on memory deficits in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned mouse model of Parkinson's disease (PD) (MPTP-lesioned mice). MPTP (30 mg/kg/day, 5 days)-lesioned mice showed deficits of habit learning memory and spatial memory, which were further aggravated by treatment with L-3,4-dihydroxyphenylalanine (L-DOPA) (25 mg/kg, 21 days). However, treatment with GP-EX (50 mg/kg, 21 days) ameliorated memory deficits in MPTP-lesioned mice treated with L-DOPA (25 mg/kg): GP-EX prevented the decreases in retention latency time in the passive avoidance test and tyrosine hydroxylase-immunopositive cells and dopamine levels in the nigrostriatum...
January 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/27975625/phytonutrients-and-bioactive-compounds-in-the-leaves-of-solenostemon-monostachyus
#7
I S Afolabi, A F Jolaoluwa, V O Awogbindin, P T Amosun
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27894779/chrysin-cocrystals-characterization-and-evaluation
#8
Renu Chadha, Yashika Bhalla, Avdesh Nandan, Kunal Chadha, Maninder Karan
Solvent free mechanochemical approach is utilized to synthesise new cocrystals of chrysin using supramolecular chemistry based upon reliable synthons. Chrysin, a flavone nutraceutical with wide range of beneficial effects has critically low bioavailability on account of its poor aqueous solubility and consequently poor absorption from the gastrointestinal tract. The present study focuses on this critical aspect and has exploited non covalent interactions to prepare its cocrystals with cytosine and thiamine hydrochloride...
February 5, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/27885783/protective-effects-of-a-novel-nutritional-and-phytonutrient-blend-on-ultraviolet-radiation-induced-skin-damage-and-inflammatory-response-through-aging-defense-mechanisms
#9
Steven M Wood, Angela F Mastaloudis, Shelly N Hester, Russell Gray, Dale Kern, Jin Namkoong, Zoe D Draelos
BACKGROUND: The human body relies on several aging defense mechanisms (ADMs) to limit damage induced from pro-aging stressors (aging aggressors). However, such protective mechanisms can be compromised, leading to accelerated aging. The skin provides a model to probe the effects of an oral nutritional intervention on ADMs in response to ultraviolet radiation (UVR)-induced damage. OBJECTIVE: To determine whether supplementation with a novel nutritional and phytonutrient blend could protect against UVR-induced skin damage and positively influence facial skin attributes and characteristics by bolstering ADMs...
November 24, 2016: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/27789382/effects-of-sesamin-on-motor-and-memory-deficits-in-an-mptp-lesioned-mouse-model-of-parkinson-s-disease-treated-with-l-dopa
#10
T T Zhao, K S Shin, K S Kim, H J Park, H J Kim, K E Lee, M K Lee
The present study investigated the effects of (-)-sesamin on motor and memory deficits in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned mouse model of Parkinson's disease (PD) with l-3,4-dihydroxyphenylalanine (l-DOPA). MPTP-lesioned (30mg/kg/day, 5days) mice showed deficits in memory including habit learning memory and spatial memory, which were further aggravated by daily treatment with 25mg/kg l-DOPA for 21days. However, daily treatment with (-)-sesamin (25 and 50mg/kg) for 21days ameliorated memory deficits in an MPTP-lesioned mouse model of PD treated with l-DOPA (25mg/kg)...
December 17, 2016: Neuroscience
https://www.readbyqxmd.com/read/27784912/implication-of-processing-and-differential-blending-on-quality-characteristics-in-nutritionally-enriched-ketchup-nutri-ketchup-from-acerola-and-tomato
#11
Anand Prakash, S H Prabhudev, M R Vijayalakshmi, Maya Prakash, Revathy Baskaran
The present study was focused on the development of nutritionally enriched ketchup (Nutri-ketchup) from acerola and tomato and evaluation of the effect of blending and processing on physicochemical characteristics, phytonutrients retention, antioxidant activity and sensorial quality. Acerola and tomato pulps blended in various ratios viz. 100:0, 75:25, 50:50, 25:75 and 0:100 were used for the preparation of five formulations of ketchup and compared with commercially available tomato ketchup. The retention of phytonutrients varied among formulations viz...
August 2016: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/27765977/physicochemical-characteristics-of-phytonutrient-retained-red-palm-olein-and-butter-fat-blends-and-its-utilization-for-formulating-chocolate-spread
#12
P K Prasanth Kumar, T Jeyarani, A G Gopala Krishna
Phytonutrients retained palm olein (PRPOL) was prepared and blended into butterfat at different ratios. The physicochemical characteristics and the phytonutrient composition of blends, as well as its utilization in the preparation of functional chocolate spread were evaluated. The results showed that the redness, yellowness, slip melting point, free fatty acids, peroxide value, iodine value, unsaponifiable matter, diacylglycerol and monoacylglycerol increased while lightness, saponification value, and triacylglycerol significantly decreased upon incorporation of increased quantities of PRPOL into butterfat...
July 2016: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/27735854/effects-of-food-components-that-activate-trpa1-receptors-on-mucosal-ion-transport-in-the-mouse-intestine
#13
Linda J Fothergill, Brid Callaghan, Leni R Rivera, TinaMarie Lieu, Daniel P Poole, Hyun-Jung Cho, David M Bravo, John B Furness
TRPA1 is a ligand-activated cation channel found in the intestine and other tissues. Components of food that stimulate TRPA1 receptors (phytonutrients) include allyl isothiocyanate, cinnamaldehyde and linalool, but these may also act at other receptors. Cells lining the intestinal mucosa are immunoreactive for TRPA1 and Trpa1 mRNA occurs in mucosal extracts, suggesting that the TRPA1 receptor is the target for these agonists. However, in situ hybridisation reveals Trpa1 expression in 5-HT containing enteroendocrine cells, not enterocytes...
October 10, 2016: Nutrients
https://www.readbyqxmd.com/read/27721818/genome-wide-identification-of-bahd-acyltransferases-and-in-vivo-characterization-of-hqt-like-enzymes-involved-in-caffeoylquinic-acid-synthesis-in-globe-artichoke
#14
Andrea Moglia, Alberto Acquadro, Kaouthar Eljounaidi, Anna M Milani, Cecilia Cagliero, Patrizia Rubiolo, Andrea Genre, Katarina Cankar, Jules Beekwilder, Cinzia Comino
Globe artichoke (Cynara cardunculus L. var. scolymus) is a rich source of compounds promoting human health (phytonutrients), among them caffeoylquinic acids (CQAs), mainly represented by chlorogenic acid (CGA), and dicaffeoylquinic acids (diCQAs). The enzymes involved in their biosynthesis belong to the large family of BAHD acyltransferases. Following a survey of the globe artichoke genome, we identified 69 BAHD proteins carrying the catalytic site (HXXXD). Their phylogenetic analysis together with another 43 proteins, from 21 species, representative of the BAHD family, highlighted their grouping in seven major clades...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27707453/proprietary-tomato-extract-improves-metabolic-response-to-high-fat-meal-in-healthy-normal-weight-subjects
#15
Xavier Deplanque, Delphine Muscente-Paque, Eric Chappuis
BACKGROUND: Low-density lipoprotein (LDL) oxidation is a risk factor for atherosclerosis. Lycopene and tomato-based products have been described as potent inhibitors of LDL oxidation. OBJECTIVES: To evaluate the effect of a 2-week supplementation with a carotenoid-rich tomato extract (CRTE) standardized for a 1:1 ratio of lycopene and phytosterols, on post-prandial LDL oxidation after a high-fat meal. DESIGN: In a randomized, double-blind, parallel-groups, placebo-controlled study, 146 healthy normal weight individuals were randomly assigned to a daily dose of CRTE standardized for tomato phytonutrients or placebo during 2 weeks...
2016: Food & Nutrition Research
https://www.readbyqxmd.com/read/27668121/ripening-dependent-changes-in-antioxidants-color-attributes-and-antioxidant-activity-of-seven-tomato-solanum-lycopersicum-l-cultivars
#16
Shiva Ram Bhandari, Jun Gu Lee
To evaluate the ripening-dependent changes in phytonutrients, seven commercial cultivars (two general and five cherry) of tomatoes were cultivated under greenhouse conditions. Fruits were harvested at breaker, turning, pink, light red, and red stages of each cultivar, and antioxidant contents, color attributes, and antioxidant activities were measured. During ripening process, lycopene content increased from the breaker to red stage, while lutein displayed the reverse accumulation pattern, with higher values during the breaker stage...
2016: Journal of Analytical Methods in Chemistry
https://www.readbyqxmd.com/read/27651255/carotenoids-and-neurobiological-health
#17
J Guest, R Grant
The consumption of carotenoid phytonutrients, largely as part of plant tissue, has been associated with a number of health benefits. Epidemiological and other studies support a link between higher dietary intake and tissue concentrations of carotenoids and lower risk of chronic diseases such as heart disease, diabetes, and some cancers. Evidence also suggests that increased levels of carotenoids can help maintain healthy cognitive function, especially into older age. Carotenoids mediate their beneficial effects via several mechanisms including cell growth regulation and modulation of gene expression and immune activity...
2016: Advances in Neurobiology
https://www.readbyqxmd.com/read/27646451/response-of-wine-grape-growth-development-and-the-transfer-of-copper-lead-and-cadmium-in-soil-fruit-system-to-sludge-compost-amendment
#18
Hong-Tao Liu, Yan-Wen Wang, Wei-Dong Huang, Mei Lei
Sludge is an organic waste after domestic sewage being treated and contains phytonutrients and organic matter. In this study, recycling of sludge compost (SC) and its compound fertilizer (SCF) to wine grape resulted in improvement in vegetative growth, reproductive development of wine grape, and potential wine quality of grape fruit. The amounts of Cu, Pb, and Cd in grape fruit were significantly higher in response to sludge amendment than in the control, but were all below the permissible limits for agricultural product...
December 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27625779/antioxidant-properties-in-some-selected-cyanobacteria-isolated-from-fresh-water-bodies-of-sri-lanka
#19
Md Fuad Hossain, R R Ratnayake, Kirisnashamy Meerajini, K L Wasantha Kumara
Phytonutrients and pigments present in cyanobacteria act as antioxidants, which facilitate the formation of body's defense mechanism against free radical damage to cells. The aim of this investigation was to study the total phenolic content (TPC), total flavonoid content (TFC), antioxidant activity, phycobiliproteins (PBPs), and active compounds in four cyanobacterial species, that is, Oscillatoria sp., Lyngbya sp., Microcystis sp., and Spirulina sp. isolated from fresh water bodies of Sri Lanka. In this study, Lyngbya sp...
September 2016: Food Science & Nutrition
https://www.readbyqxmd.com/read/27475678/promising-therapeutic-potential-of-pterostilbene-and-its-mechanistic-insight-based-on-preclinical-evidence
#20
REVIEW
Ramoji Kosuru, Uddipak Rai, Swati Prakash, Abhishank Singh, Sanjay Singh
Pterostilbene (PS) is a well-recognized antioxidant that primarily exists in blueberries, grapevines and heartwood of red sandalwood. Interest in this compound has been renewed in recent years, and studies have found that PS possesses an array of pharmacological properties, including chemopreventive, antiinflammatory, antidiabetic, antidyslipidemic, antiatherosclerotic and neuroprotective effects. However, the greater in vivo bioavailability of PS, as compared to resveratrol, is an added advantage for its efficacy...
October 15, 2016: European Journal of Pharmacology
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