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https://www.readbyqxmd.com/read/28822256/addressing-harmful-algal-blooms-habs-impacts-with-ferrate-vi-simultaneous-removal-of-algal-cells-and-toxins-for-drinking-water-treatment
#1
Yang Deng, Meiyin Wu, Huiqin Zhang, Lei Zheng, Yaritza Acosta, Tsung-Ta D Hsu
Although ferrate(VI) has long been recognized as a multi-purpose treatment agent, previous investigations regarding ferrate(VI) for addressing harmful algal blooms (HABs) impacts in drinking water treatment only focused on a single HAB pollutant (e.g. algal cells or algal toxins). Moreover, the performance of ferrate(VI)-driven coagulation was poorly investigated in comparison with ferrate(VI) oxidation, though it has been widely acknowledged as a major ferrate(VI) treatment mechanism. We herein reported ferrate(VI) as an emerging agent for simultaneous and effective removal of algal cells and toxins in a simulated HAB-impacted water...
August 11, 2017: Chemosphere
https://www.readbyqxmd.com/read/28822247/mobile-phones-an-asset-or-a-liability-a-study-based-on-characterization-and-assessment-of-metals-in-waste-mobile-phone-components-using-leaching-tests
#2
Meenakshi Hira, Sudesh Yadav, P Morthekai, Anurag Linda, Sushil Kumar, Anupam Sharma
The prolonged use of old fashioned gadgets, especially mobile phones, is declining readily with the advancement in technology which ultimately lead to generation of e-waste. The present study investigates the concentrations of nine metals (Ba, Cd, Cr, Cu, Fe, Ni, Pb, Sn, and Zn) in various components of the mobile phones using Toxicity Characteristic Leaching Procedure (TCLP), Waste Extraction Test (WET) and Synthetic Precipitation Leaching Procedure (SPLP). The results were compared with the threshold limits for hazardous waste defined by the California Department of Toxic Substances Control (CDTSC) and United States Environmental Protection Agency (USEPA)...
August 5, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28822046/body-mass-index-and-clinical-response-to-intravenous-or-subcutaneous-abatacept-in-patients-with-rheumatoid-arthritis
#3
Maria-Antonietta D'Agostino, Rieke Alten, Eduardo Mysler, Manuela Le Bars, June Ye, Bindu Murthy, Julia Heitzmann, Radu Vadanici, Gianfranco Ferraccioli
This post hoc analysis of ACQUIRE (NCT00559585) explored the effect of baseline body mass index (BMI) on the pharmacokinetics of and clinical response to subcutaneous (SC) or intravenous (IV) abatacept in patients with rheumatoid arthritis (RA). ACQUIRE was a phase 3b, 6-month, double-blind, double-dummy study in which patients with RA were randomized (1:1) to SC (fixed - dose; 125 mg/week) or IV (weight-tiered; ~ 10 mg/kg/month) abatacept plus methotrexate. In this analysis, minimum abatacept plasma concentration (Cmin) was measured at 3 and 6 months, and clinical remission over 6 months was assessed by Disease Activity Score 28 (C-reactive protein; DAS28 [CRP], < 2...
August 18, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28822015/experimental-periodontitis-in-the-potentialization-of-the-effects-of-immobilism-in-the-skeletal-striated-muscle
#4
Marcela Aparecida Leite, Tatiane Morgenstern de Mattia, Camila Mayumi Martin Kakihata, Bruna Martinazzo Bortolini, Pedro Henrique de Carli Rodrigues, Gladson Ricardo Flor Bertolini, Rose Meire Costa Brancalhão, Lucinéia de Fátima Chasko Ribeiro, Carlos Augusto Nassar, Patrícia Oehlmeyer Nassar
This study aims to evaluate if ligature-induced periodontitis can potentiates the deleterious effects of immobilization in the skeletal striated muscle, contributing to the development of muscle atrophy due to disuse. Forty Wistar rats were divided into four groups: (1) Control Group (CG), (2) Periodontal Disease (PDG), (3) Immobilized (IG), and (4) Immobilized with Periodontal Disease (IPDG). Periodontal disease was induced for 30 days, with ligature method, and the immobilization was performed with cast bandage for 15 days...
August 18, 2017: Inflammation
https://www.readbyqxmd.com/read/28821945/the-effect-of-thyroid-autoantibody-positivity-on-the-functions-of-internal-ear
#5
Akif Gunes, Mehmet Fatih Karakus, Tugba Akin Telli, Nurcan Akbas Gunes, Murad Mutlu
The objective of the study is to investigate if any significant difference exists in hearing thresholds and tympanometric examination results among patients whose thyroid antibody positivity was detected approximately 1 year or at least 5 years ago. Study population aged less than 40 years consisted of 17 patients who had thyroid antibody positivities for an average of 1 year (first group), 15 patients who were followed up for at least 5 years for thyroid antibody positivity (second group), and 18 volunteers (third group)...
August 18, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28821920/tspo-pet-for-glioma-imaging-using-the-novel-ligand-18-f-ge-180-first-results-in-patients-with-glioblastoma
#6
Nathalie L Albert, M Unterrainer, D F Fleischmann, S Lindner, F Vettermann, A Brunegraf, L Vomacka, M Brendel, V Wenter, C Wetzel, R Rupprecht, J-C Tonn, C Belka, P Bartenstein, M Niyazi
OBJECTIVE: The 18-kDa mitochondrial translocator protein (TSPO) was reported to be upregulated in gliomas. (18)F-GE-180 is a novel 3rd generation TSPO receptor ligand with improved target-to-background contrast compared to previous tracers. In this pilot study, we compared PET imaging with (18)F-GE-180 and MRI of patients with untreated and recurrent pretreated glioblastoma. METHODS: Eleven patients with histologically confirmed IDH wildtype gliomas (10 glioblastomas, 1 anaplastic astrocytoma) underwent (18)F-GE-180 PET at initial diagnosis or recurrence...
August 19, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28821739/ultrafast-photonic-reinforcement-learning-based-on-laser-chaos
#7
Makoto Naruse, Yuta Terashima, Atsushi Uchida, Song-Ju Kim
Reinforcement learning involves decision making in dynamic and uncertain environments and constitutes an important element of artificial intelligence (AI). In this work, we experimentally demonstrate that the ultrafast chaotic oscillatory dynamics of lasers efficiently solve the multi-armed bandit problem (MAB), which requires decision making concerning a class of difficult trade-offs called the exploration-exploitation dilemma. To solve the MAB, a certain degree of randomness is required for exploration purposes...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821553/epidemiology-of-discordance-between-symptoms-and-signs-of-dry-eye
#8
Erin S Ong, Elizabeth R Felix, Roy C Levitt, William J Feuer, Constantine D Sarantopoulos, Anat Galor
BACKGROUND/AIMS: The frequent lack of association between dry eye (DE) symptoms and signs leads to challenges in diagnosing and assessing the disease. METHODS: Participants underwent ocular surface examinations to evaluate signs of disease and completed questionnaires to assess ocular symptoms, psychological status and medication use. To assess nociceptive system integrity, quantitative sensory testing (QST), including vibratory and thermal threshold measures and temporal summation of pain were obtained at the forearm and forehead...
August 18, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28821524/the-association-between-intensive-care-unit-acquired-hypernatraemia-and-mortality-in-critically-ill-patients-with-cerebrovascular-diseases-a-single-centre-cohort-study-in-japan
#9
Takahiro Imaizumi, Masahiro Nakatochi, Yoshiro Fujita, Rie Nomura, Kenshi Watanabe, Michitaka Maekawa, Taishi Yamakawa, Takayuki Katsuno, Shoichi Maruyama
OBJECTIVES: Hypernatraemia is one of the major electrolyte disorders associated with mortality among critically ill patients in intensive care units (ICUs). It is unclear whether this applies to patients with cerebrovascular diseases in whom high sodium concentrations may be allowed in order to prevent cerebral oedema. This study aimed to examine the association between ICU-acquired hypernatraemia and the prognosis of patients with cerebrovascular diseases. DESIGN: A retrospective cohort study...
August 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28821492/use-of-the-low-frequency-high-frequency-ratio-of-heart-rate-variability-to-predict-short-term-deterioration-in-emergency-department-patients-with-sepsis
#10
Douglas P Barnaby, Shannon M Fernando, Kevin J Ferrick, Christophe L Herry, Andrew J E Seely, Polly E Bijur, E John Gallagher
OBJECTIVE: To examine the ability of the low-frequency/high-frequency (LF/HF) ratio of heart rate variability (HRV) analysis to identify patients with sepsis at risk of early deterioration. METHODS: This is a prospective observational cohort study of patients with sepsis presenting to the Montefiore Medical Center ED from December 2014 through September 2015. On presentation, a single ECG Holter recording was obtained and analysed to obtain the LF/HF ratio of HRV...
August 18, 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/28821485/simple-evaluation-method-for-cyp3a4-induction-from-human-hepatocytes-the-relative-factor-approach-with-an-induction-detection-limit-concentration-based-on-the-emax-model
#11
Shino Kuramoto, Motohiro Kato, Hidetoshi Shindoh, Akihisa Kaneko, Masaki Ishigai, Seiji Miyauchi
We investigated the robustness and utility of the relative factor (RF) approach based on the Emax model, which was reported by Kaneko, using mRNA induction data of 10 typical CYP3A4 inducers in cryopreserved human hepatocytes. The RF value is designated as the ratio of the induction detection limit concentration (IDLC) for a standard inducer, such as rifampicin (RIF) or phenobarbital (PB), to that for the compound (RFRIF is IDLCRIF/IDLCcpd; RFPB is IDLCPB/IDLCcpd). An important feature of the RF approach is that the profiles of the induction response curves on the logarithmic scale remain unchanged irrespective of inducers but are shifted parallel depending on the EC50 values...
August 18, 2017: Drug Metabolism and Disposition: the Biological Fate of Chemicals
https://www.readbyqxmd.com/read/28821205/cerebrospinal-fluid-circulating-tumor-cells-a-novel-tool-to-diagnose-leptomeningeal-metastases-from-epithelial-tumors
#12
Xuling Lin, Martin Fleisher, Marc Rosenblum, Oscar Lin, Adrienne Boire, Samuel Briggs, Yevgeniya Bensman, Brenda Hurtado, Larisa Shagabayeva, Lisa M DeAngelis, Katherine S Panageas, Antonio Omuro, Elena I Pentsova
Background: Diagnosis of leptomeningeal metastasis (LM) remains challenging due to low sensitivity of CSF cytology and infrequent unequivocal MRI findings. In a previous pilot study, we showed that rare cell capture technology (RCCT) could be used to detect circulating tumor cells (CTC) in the CSF of patients with LM from epithelial tumors. To establish the diagnostic accuracy of CSF-CTC in the diagnosis of LM, we applied this technique in a distinct, larger cohort of patients. Methods: In this institutional review board-approved prospective study, patients with epithelial tumors and clinical suspicion of LM underwent CSF-CTC evaluation and standard MRI and CSF cytology examination...
September 1, 2017: Neuro-oncology
https://www.readbyqxmd.com/read/28821191/impact-of-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-features-on-adequacy-criteria-and-risk-of-malignancy-of-thyroid-fine-needle-aspiration
#13
Andrew A Renshaw, Edwin W Gould
Objectives: The impact of noninvasive follicular thyroid neoplasm with papillary-like features (NIFTP) on nondiagnostic and benign diagnoses is not well characterized. Methods: The results of all thyroid fine-needle aspirates (FNAs) performed from 1997 to June 2016 with corresponding resections were reviewed. Results: From 12,764 aspirates, there were 8,106 (64%) benign diagnoses with 412 (5%) resections and 1,888 (14.8%) nondiagnostic diagnoses with 329 (17%) resections...
September 1, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28821179/pungency-evaluation-of-hydroxyl-sanshool-compounds-after-dissolution-in-taste-carriers-per-time-related-characteristics
#14
Lulu Zhang, Bolin Shi, Houyin Wang, Lei Zhao, Zhongxiu Chen
This study was conducted to investigate the sensory characteristics and temporal migration of hydroxyl-sanshool compounds at slight and moderate concentrations after dissolution in ethanol-water, saccharose, NaCl, and MSG via 2-AFC, time intensity (TI) and temporal dominance of sensations (TDS) methods. The pungency detection threshold (DT) was suppressed in saccharose while NaCl and MSG solutions showed no effect on pungency DT. The area under the curve (AUC) of pungency increased in NaCl and MSG solutions and decreased significantly in saccharose solution...
September 1, 2017: Chemical Senses
https://www.readbyqxmd.com/read/28821178/oil-perception-detection-thresholds-for-varying-fatty-stimuli-and-inter-individual-differences
#15
Jaana M Heinze, Andrew Costanzo, Inga Baselier, Andreas Fritsche, Melanie Lidolt, Jörg Hinrichs, Sabine Frank-Podlech, Russell Keast
Multiple lines of research have demonstrated that humans can perceive fat in the form of free fatty acids (FFAs). However, the dietary concentration of FFAs is generally very low and fat is mainly consumed as triacylglycerol (TAG). The aim of this study was to examine the perception of different fatty stimuli and possible associations between them. Therefore, detection thresholds for 4 fatty stimuli (oleic acid [FFA], paraffin oil [mixture of hydrocarbon molecules], canola oil [TAG-rich], and canola oil spiked with oleic acid [rich in TAGs and FFAs]) were determined in 30 healthy participants...
September 1, 2017: Chemical Senses
https://www.readbyqxmd.com/read/28821041/regulation-of-structure-rheological-and-surface-properties-of-chitin-nanocrystal-dispersions
#16
M A Torlopov, I S Martakov, V I Mikhaylov, N V Tsvetkov, P V Krivoshapkin
The hydrosols of chitin nanocrystals (ChN) are promising as modifiers of properties, drug delivery systems, and media. The purpose of this work is to clarify the mechanisms for regulating processes of stability and structure formation occurring in the ChN hydrosols under the influence of varying ionic strength. ChN were isolated from the crab shell; ChN hydrosols are obtained with different concentrations of the dispersed phase. The structure and morphology of the particles was studied by atomic force microscopy and X-ray diffraction...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28820905/estimating-the-evidential-value-of-significant-results-in-psychological-science
#17
Balazs Aczel, Bence Palfi, Barnabas Szaszi
Quantifying evidence is an inherent aim of empirical science, yet the customary statistical methods in psychology do not communicate the degree to which the collected data serve as evidence for the tested hypothesis. In order to estimate the distribution of the strength of evidence that individual significant results offer in psychology, we calculated Bayes factors (BF) for 287,424 findings of 35,515 articles published in 293 psychological journals between 1985 and 2016. Overall, 55% of all analyzed results were found to provide BF > 10 (often labeled as strong evidence) for the alternative hypothesis, while more than half of the remaining results do not pass the level of BF = 3 (labeled as anecdotal evidence)...
2017: PloS One
https://www.readbyqxmd.com/read/28820891/scene-text-detection-via-extremal-region-based-double-threshold-convolutional-network-classification
#18
Wei Zhu, Jing Lou, Longtao Chen, Qingyuan Xia, Mingwu Ren
In this paper, we present a robust text detection approach in natural images which is based on region proposal mechanism. A powerful low-level detector named saliency enhanced-MSER extended from the widely-used MSER is proposed by incorporating saliency detection methods, which ensures a high recall rate. Given a natural image, character candidates are extracted from three channels in a perception-based illumination invariant color space by saliency-enhanced MSER algorithm. A discriminative convolutional neural network (CNN) is jointly trained with multi-level information including pixel-level and character-level information as character candidate classifier...
2017: PloS One
https://www.readbyqxmd.com/read/28820651/starting-and-stopping-kinetics-of-a-rear-mounted-power-assist-for-manual-wheelchairs
#19
Stephanie Wong, Ben Mortenson, Bonita Sawatzky
A rear mounted, powered, drive wheel has been developed to assist with mobility for manual wheelchairs in indoor and outdoor modes. To start the wheel, users must initiate handrim propulsion with sufficient force to trigger the motor. To stop the indoor mode, users must apply a braking force through the handrims exceeding the device's deceleration threshold. The objectives of this study were to compare 1) the minimum force required to start a wheelchair with and without the wheel, and 2) the distances and forces needed to stop a wheelchair at different treadmill speeds (3...
August 18, 2017: Assistive Technology: the Official Journal of RESNA
https://www.readbyqxmd.com/read/28820302/letter-to-the-editor-an-extent-of-resection-threshold-for-recurrent-glioblastoma-why-wait-until-recurrence
#20
Gentian Kaloshi, Mentor Petrela
No abstract text is available yet for this article.
August 18, 2017: Journal of Neurosurgery
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