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https://www.readbyqxmd.com/read/29241094/adhesion-of-human-monocytes-to-oxygen-and-nitrogen-containing-plasma-polymers-effect-of-surface-chemistry-and-protein-adsorption
#1
Sara Babaei, Natalie Fekete, Corinne A Hoesli, Pierre-Luc Girard-Lauriault
The interactions between monocytes and biomaterials can potentially be modulated by controlling the chemical and structural surface properties of biomaterials. The objective of this study was to determine the effect of plasma-deposited functional organic coatings on monocyte adhesion and differentiation into macrophages. Organic coatings with varying oxygen and nitrogen concentration were prepared by low-pressure plasma co-polymerization of binary gas mixtures combining a hydrocarbon (butadiene/ethylene) and a heteroatom-containing gas (carbon dioxide/ammonia) to deposit either oxygen or nitrogen-containing coatings...
December 6, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29241033/the-elimination-of-positive-priming-with-increasing-prime-duration-reflects-a-transition-from-perceptual-fluency-to-disfluency-rather-than-bias-against-primed-words
#2
Kevin W Potter, Chris Donkin, David E Huber
With immediate repetition priming of forced choice perceptual identification, short prime durations produce positive priming (i.e., priming the target leads to higher accuracy, while priming the foil leads to lower accuracy). Many theories explain positive priming following short duration primes as reflecting increased perceptual fluency for the primed target (i.e., decreased identification latency). However, most studies only examine either accuracy or response times, rather than considering the joint constraints of response times and accuracy to properly address the role of decision biases and response caution...
December 11, 2017: Cognitive Psychology
https://www.readbyqxmd.com/read/29241019/quantitative-analysis-of-a-multiplexed-immunofluorescence-panel-in-t-cell-lymphoma
#3
Siok-Bian Ng, Shuangyi Fan, Shoa-Nian Choo, Michal Hoppe, Hoang Mai Phuong, Sanjay De Mel, Anand D Jeyasekharan
Immunohistochemistry (IHC) provides clinically useful information on protein expression in cancer cells. However, quantification of colocalizing signals using conventional IHC and visual scores is challenging. Here we describe the application of quantitative immunofluorescence in angioimmunoblastic T-cell lymphoma (AITL), a peripheral T-cell lymphoma characterized by cellular heterogeneity that impedes IHC interpretation and quantification. A multiplexed immunofluorescence (IF) panel comprising T- and B-lymphocyte markers along with T-follicular helper (TFH) markers was validated for appropriate cellular localization in sections of benign tonsillar tissue and tested in two samples of AITL, using a Vectra microscope for spectral imaging and InForm software for analysis...
December 1, 2017: SLAS Technology
https://www.readbyqxmd.com/read/29241008/efficient-step-like-carrier-multiplication-in-percolative-networks-of-epitaxially-connected-pbse-nanocrystals
#4
Aditya Kulkarni, Wiel H Evers, Stanko Tomic, Matthew C Beard, Daniël Vanmaekelbergh, Laurens D A Siebbeles
Carrier multiplication (CM) is a process in which a single photon excites two or more electrons. CM is of interest to enhance the efficiency of a solar cell. Until now, CM in thin films and solar cells of semiconductor nanocrystals (NCs) has been found at photon energies well above the minimum required energy of twice the band gap. The high threshold of CM strongly limits the benefits for solar cell applications. We show that CM is more efficient in a percolative network of directly connected PbSe NCs. The CM threshold is at twice the band gap and increases in a step-like fashion with photon energy...
December 14, 2017: ACS Nano
https://www.readbyqxmd.com/read/29240842/analysis-of-ecological-thresholds-in-a-temperate-forest-undergoing-dieback
#5
Philip Martin, Adrian C Newton, Elena Cantarello, Paul M Evans
Positive feedbacks in drivers of degradation can cause threshold responses in natural ecosystems. Though threshold responses have received much attention in studies of aquatic ecosystems, they have been neglected in terrestrial systems, such as forests, where the long time-scales required for monitoring have impeded research. In this study we explored the role of positive feedbacks in a temperate forest that has been monitored for 50 years and is undergoing dieback, largely as a result of death of the canopy dominant species (Fagus sylvatica, beech)...
2017: PloS One
https://www.readbyqxmd.com/read/29240758/increased-gamma-band-activity-for-lateral-interactions-in-humans
#6
Alon Shapira, Anna Sterkin, Moshe Fried, Oren Yehezkel, Zeev Zalevsky, Uri Polat
Collinear facilitation of contrast sensitivity supported by lateral interactions within primary visual cortex is implicated in contour and object perception, with neural correlates in several frequency bands. Although higher component of the ERP power spectrum, the gamma-band, is postulated to reflect object representation, attention and memory, its neuronal source has been questioned, suggesting it is an artifact reflecting saccadic eye movements. Here we explored the gamma-band activity during collinear facilitation with no saccade-related confounds...
2017: PloS One
https://www.readbyqxmd.com/read/29240247/do-we-still-need-oral-food-challenges-for-the-diagnosis-of-food-allergy
#7
REVIEW
Philippe A Eigenmann
Food challenges are standard in the diagnosis in patients suspected of being allergic to food. However, their role is regularly questioned due to the time required to perform them, and to their cost and the inherent risk of severe reactions. Food challenges have been challenged by recent advances defining threshold values for food-specific IgE helping to predict the probability of having symptoms to the suspected food. Also, identification of major allergens to various highly allergenic foods such as peanuts or tree nuts have contributed to an increased accuracy of IgE testing...
December 14, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/29240208/effect-of-different-intraradicular-posts-on-the-color-of-the-buccal-gingiva-at-teeth-restored-with-zirconia-crowns
#8
Karin Wolleb Torrisi, Goran I Benic, Irena Sailer, Christoph Hf Hämmerle
The purpose of this study was to test whether prosthetic treatment with different intraradicular posts influences the color of the buccal gingiva at teeth restored with zirconia crowns. A total of 31 patients in need of a full-coverage single crown at an endodontically treated premolar, canine, or incisor in the maxilla or the mandible were included. The patients were randomly assigned to receive composite build-ups using titanium (Ti), zirconia (Zi), or glass-fiber (Gf) posts or a build-up using no post at all (NP)...
January 2018: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29240195/sub-rayleigh-resolution-ghost-imaging-by-spatial-low-pass-filtering
#9
Xi-Hao Chen, Fan-Hui Kong, Qiang Fu, Shao-Ying Meng, Ling-An Wu
A sub-Rayleigh resolution ghost imaging experiment is performed via post-detection spatial low-pass filtering of the instantaneous intensity. A super-resolution reconstructed image has been achieved, in which the spatial resolution can exceed the Rayleigh diffraction limit by more than a factor of two. The resolution depends on the filter threshold, and the Rayleigh limit can be exceeded for a wide choice of threshold values. The setup is simple and easy to implement, which is an advantage for practical applications...
December 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/29240180/experimental-study-of-the-mode-instability-onset-threshold-in-high-power-fa-lpf-lasers
#10
Marie-Alicia Malleville, Romain Dauliat, Aurélien Benoît, Baptiste Leconte, Dia Darwich, Rémi du Jeu, Raphaël Jamier, Kay Schuster, Philippe Roy
We report here on an experimental investigation of the temporal behavior of transverse mode instabilities into "fully aperiodic large-pitch fibers" (FA-LPFs) operated in high-power continuous-wave laser configuration. To ensure an effective transverse single-mode emission into FA-LPFs, a perfect index matching between the active core and the background cladding materials (Δn=0) is required. The original design of such fibers enables an effective transverse single-mode emission by strengthening the higher-order mode delocalization out of the gain region, even for high heat load levels, consequently leading to the improvement of the beam spatial quality...
December 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/29240160/single-shot-real-time-carrier-envelope-phase-measurement-and-tagging-based-on-stereographic-above-threshold-ionization-at-short-wave-infrared-wavelengths
#11
Yinyu Zhang, Philipp Kellner, Daniel Adolph, Danilo Zille, Philipp Wustelt, Daniel Würzler, Slawomir Skruszewicz, Max Möller, A Max Sayler, Gerhard G Paulus
A high-precision, single-shot, and real-time carrier-envelope phase (CEP) measurement at 1.8 μm laser wavelength based on stereographic photoelectron spectroscopy is presented. A precision of the CEP measurement of 120 mrad for each and every individual laser shot for a 1 kHz pulse train with randomly varying CEP is demonstrated. Simultaneous to the CEP measurement, the pulse lengths are characterized by evaluating the spatial asymmetry of the measured above-threshold ionization (ATI) spectra of xenon and referenced to a standard pulse-duration measurement based on frequency-resolved optical gating...
December 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/29240132/improvement-of-high-power-laser-performance-for-super-smooth-optical-surfaces-using-electrorheological-finishing-technology
#12
Hao Yang, Haobo Cheng, Yunpeng Feng
Laser-induced damage threshold (LIDT) is a key parameter for optical components heavily influenced by the surface roughness in high-power laser uses. Present polishing technologies often bring about directional micro waviness to the optical surfaces due to path effect. Roughness features of a K9 glass surface were studied in this paper. A new evaluating restriction for power spectral density specification was established, and the off-specification frequency contents were found out. Then the electromagnetic simulation of light field modulation was carried out, and the field enhancement factor reached 12...
December 10, 2017: Applied Optics
https://www.readbyqxmd.com/read/29240107/designing-a-low-threshold-quantum-dot-laser-based-on-a-slow-light-photonic-crystal-waveguide
#13
Hussein Taleb, Mohammad Kazem Moravvej-Farshi
We numerically investigate and design a compact electrically pumped edge-emitting photonic crystal waveguide (PCW) quantum dot (QD) laser operating at room temperature. Use of a narrowband folded directional coupler as the output mirror has made the proposed structure an edge-emitting single-mode laser. Moreover, we propose a set of rate equations to model the performance of the PCW-QD laser. In the proposed model, we take the effects of the homogeneous and inhomogeneous broadenings and the slow-light effects on the modal gain and loss coefficient into account...
December 10, 2017: Applied Optics
https://www.readbyqxmd.com/read/29240020/association-study-of-fgf18-with-developmental-dyslexia-in-chinese-population
#14
Huan Chen, Yuxi Zhou, Zeng Ge, Qian Li, Qinsheng Sun, Liyuan Zheng, Hong Lv, Li-Hai Tan, Yimin Sun
Developmental dyslexia (DD) is a neurobiological disorder featured by reading disabilities. In recent years, genome-wide approaches provided new perspectives to discover novel candidate genes of DD. In a previous study, rs9313548 located downstream of FGF18 showed borderline genome-wide significant association with DD. Herein, we selected rs9313548 and 11 independent tag single nucleotide polymorphisms covering gene region of FGF18 to perform association analysis with DD among 978 Chinese dyslexic cases and 998 controls recruited from elementary schools...
December 12, 2017: Psychiatric Genetics
https://www.readbyqxmd.com/read/29239986/practical-model-of-low-volume-paddling-based-sprint-interval-training-improves-aerobic-and-anaerobic-performances-in-professional-female-canoe-polo-athletes
#15
Mohsen Sheykhlouvand, Erfan Khalili, Mohammadali Gharaat, Hamid Arazi, Mousa Khalafi, Bahman Tarverdizadeh
Brief, intense exercise training employing running and cycling as exercise interventions may induce aerobic and anaerobic adaptations in athletes from wide range of sports. However, this has not been studied extensively for those sports in which the upper-body is predominantly involved. Our purpose was to examine the effects of kayak paddling-based sprint interval training (SIT) on cardiorespiratory fitness and anaerobic performance. 16 professional female canoe polo athletes (age = 27.6 ± 1.9 years; height = 165...
December 11, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29239983/effects-of-2-dehydration-on-lactate-concentration-during-constant-load-cycling
#16
J M Green, Miller Bl, J D Simpson, Dubroc Dr, Keyes Aa, Neal Kk, Gann Jj, Andre Tl
The lactate [La] threshold can predict endurance performance potential. Dehydration may alter [La] threshold. This study examined effects of dehydration on [La] response during constant load cycling. Recreationally fit (VO2 peak = 48.7 ± 5.2 ml•kg•min) male participants (n=9) completed 2 x 40 min constant-load cycling trials; euhydrated (HYD) and following previous evening passive (water bath) dehydration (2% body weight, DEH) (HYD and DEH counterbalanced). [La], heart rate (HR), 10 point Omni Ratings of Perceived Exertion (RPE) and rectal temperature (Trec) were measured following warm-up and at 10, 20, 30, and 40 min...
December 11, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29239979/monitoring-haloperidol-plasma-concentration-and-associated-adverse-events-in-critically-ill-children-with-delirium-first-results-of-a-clinical-protocol-aimed-to-monitor-efficacy-and-safety
#17
Valerie D Slooff, Desley K van den Dungen, Babette S van Beusekom, Naomi Jessurun, Erwin Ista, Dick Tibboel, Saskia N de Wildt
OBJECTIVES: As delirium in critically ill children is increasingly recognized, more children are treated with the antipsychotic drug haloperidol, while current dosing guidelines are lacking solid evidence and appear to be associated with a high risk of adverse events. We aim to report on the safety and efficacy of a recently implemented clinical dose-titration protocol with active monitoring of adverse events. DESIGN: From July 2014 until June 2015, when a potential delirium was identified by regular delirium scores and confirmed by a child psychiatrist, haloperidol was prescribed according to the Dutch Pediatric Formulary...
December 12, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29239901/prevention-of-hiv-1-transmission-through-breastfeeding-efficacy-and-safety-of-maternal-antiretroviral-therapy-versus-infant-nevirapine-prophylaxis-for-duration-of-breastfeeding-in-hiv-1-infected-women-with-high-cd4-cell-count-impaact-promise-a-randomized-open
#18
Patricia M Flynn, Taha E Taha, Mae Cababasay, Mary Glenn Fowler, Lynne M Mofenson, Maxensia Owor, Susan Fiscus, Lynda Stranix-Chibanda, Anna Coutsoudis, Devasena Gnanashanmugam, Nahida Chakhtoura, Katie McCarthy, Cornelius Mukuzunga, Bonus Makanani, Dhayendre Moodley, Teacler Nematadzira, Bangini Kusakara, Sandesh Patil, Tichaona Vhembo, Raziya Bobat, Blandina T Mmbaga, Maysseb Masenya, Mandisa Nyati, Gerhard Theron, Helen Mulenga, Kevin Butler, David E Shapiro
BACKGROUND: No randomized trial has directly compared the efficacy of prolonged infant antiretroviral prophylaxis versus maternal antiretroviral therapy (mART) for prevention of mother-to-child transmission throughout the breastfeeding period. SETTING: Fourteen sites in sub-Saharan Africa and India. METHODS: A randomized, open label strategy trial was conducted in HIV-1-infected women with CD4 counts >350 cells/mm (or >country-specific ART threshold if higher) and their breastfeeding HIV-1-uninfected newborns...
December 11, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29239900/isoniazid-preventive-therapy-for-people-with-hiv-who-are-heavy-alcohol-drinkers-in-high-tb-hiv-burden-countries-a-risk-benefit-analysis
#19
J Morgan Freiman, Karen R Jacobson, Winnie R Muyindike, C Robert Horsburgh, Jerrold J Ellner, Judith A Hahn, Benjamin P Linas
BACKGROUND: Isoniazid preventive therapy (IPT) reduces mortality among people living with HIV (PLHIV), and is recommended for those without active tuberculosis (TB) symptoms. Heavy alcohol use, however, is contraindicated for liver toxicity concerns. We evaluated the risks and benefits of IPT at antiretroviral therapy (ART) initiation to ART alone for PLHIV who are heavy drinkers in three high TB/HIV burden countries. METHODS: We developed a Markov simulation model to compare ART alone to ART with either 6 or 36 months of IPT for heavy drinking PLHIV enrolling in care in Brazil, India, and Uganda...
December 6, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29239861/capacitance-voltage-analysis-of-electrical-properties-for-wse2-field-effect-transistors-with-high-k-encapsulation-layer
#20
Seung-Pil Ko, Jong Mok Shin, Ho-Kyun Jang, Min Youl You, Jun-Eon Jin, Miri Choi, Jiung Cho, Gyu-Tae Kim
Doping effects in devices based on two-dimensional materials have been widely studied. However, detailed analysis and mechanism of the doping effect caused by encapsulation layers has not been sufficiently explored. In this work, we present experimental studies on the n-doping effect in WSe2 field effect transistors (FETs) with high-k encapsulation layer (Al2O3) grown by atomic layer deposition (ALD). In addition, we demonstrate the mechanism and origin of the doping effect. After encapsulation of the Al2O3 layer, the threshold voltage of the WSe2 FET negatively shifted with the increase of the on-current...
December 14, 2017: Nanotechnology
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