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https://www.readbyqxmd.com/read/29161699/patterns-of-detection-of-fetal-posterior-fossa-anomalies-analysis-of-81-cases-in-the-second-half-of-gestation
#1
Stéphanie Friszer, Ferdinand Dhombres, Eléonore Blondiaux, Marie-Laure Moutard, Catherine Garel, Jean-Marie Jouannic
OBJECTIVE: To establish which characteristics of fetal ultrasound screening lead to the diagnosis of posterior fossa (PF) anomalies. METHODS: A total of 81 fetuses with PF anomalies diagnosed after dedicated neuroimaging between July 1, 2007, and January 1, 2013, were included. The ultrasound characteristics of the fetal cerebellum categorized according to an anatomical approach to the PF, associated fetal anomalies, gestational age at diagnosis, and the potential benefits from systematic measurement of the transverse cerebellar diameter (TCD) were analyzed...
November 21, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/29157167/%C3%AE-s-globin-gene-haplotype-and-the-stroke-risk-among-egyptian-children-with-sickle-cell-disease
#2
Heba H Abou-Elew, Ilham Youssry, Shireen Hefny, Rania H Hashem, Nevine Fouad, Rania A Zayed
BACKGROUND AND AIM OF WORK: Sickle cell disease (SCD) is an inherited disease of the beta globin gene. The β(S) globin gene haplotypes are Senegal, Benin, Bantu, Cameroon, Arab-Indian and atypical haplotypes. In SCD, stroke is a life-threatening event in both adults and children. In light of paucity of studies on β(S) globin gene haplotypes in Egypt, we aimed to determine β(S) globin gene haplotypes in children with SCD and study their impact on stroke risk. METHODS: Fifty-two SCD patients were included in the study, they were 26 males and 26 females with age range from 3 to 18 years old...
November 20, 2017: Hematology (Amsterdam, Netherlands)
https://www.readbyqxmd.com/read/29153664/microcirculatory-blood-flow-derangements-during-severe-preeclampsia-and-hellp-syndrome
#3
Gustavo Adolfo Ospina-Tascón, Albaro José Nieto Calvache, Edgardo Quiñones, Humberto José Madriñan, Juan David Valencia, William Fernando Bermúdez, Javier Carvajal, María Fernanda Escobar, Daniel de Backer
OBJECTIVE: To evaluate the microcirculatory blood flow in severe preeclampsia and compare it with healthy pregnant and non-pregnant women controls, using a portable intravital-microscopy technique. METHODS: Using a side-stream dark field (SDF) device, we prospectively evaluated the sublingual microcirculatory blood flow before placental delivery in 40 women with severe preeclampsia (PE-group) complicated (n=8) or not (n=32) with HELLP syndrome, 40 healthy pregnant women (HP-group) matched by gestational and chronological age, and 20 healthy non-pregnant women (NP-group)...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29137102/lateral-medullary-infarction-with-similar-features-of-brown-sequard-syndrome-caused-by-vertebrobasilar-dysplasia-and-klippel-feil-syndrome-a-case-report
#4
Jingzhe Han, Duanhua Cao, Guomei Ma, Tingting Wang, Ye Ji, Zhilei Kang
RATIONALE: Patients with Klippel-Feil syndrome (KFS) are always anomaly associated with vertebrobasilar dysplasia. That may present commonly as infarction of brainstem, medulla, and cerebellum. In this article, we reported a rare case of lateral medullary infarction (LMI) with similar features of Brown Sequard syndrome caused by vertebrobasilar dysplasia and KFS, and the 2 rare conditions that are causally related. The case is being reported because of its unusual and rare presentation...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29132821/determination-of-the-content-of-alkyl-ketene-dimer-in-its-latex-by-an-ionic-liquid-assisted-headspace-gas-chromatography
#5
Ning Yan, Xiao-Fang Wan, Xin-Sheng Chai, Run-Quan Chen, Chun-Xia Chen
This paper reports on an ionic-liquid assisted headspace gas chromatographic (HS-GC) for the determination of the content of alkyl ketene dimer (AKD) in its latex samples, in which the GC system was equipped with a thermal conductivity detector (TCD). The method was based on the AKD hydrolysis conducted in 1-butyl-3-methylimidazolium chloride (ionic-liquid) added medium at 100°C for 10min in a closed headspace sample vial, and the measured CO2 (the resulting product of the hydrolysis) by HS-GC. The results showed that the present method has a good measurement precision (RSD <2...
November 7, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29130477/transcranial-doppler-and-lower-extremity-function-in-older-adults-einstein-aging-study
#6
Ali Ezzati, Tatjana Rundek, Joe Verghese, Carol A Derby
OBJECTIVES: To determine whether transcranial Doppler ultrasound (TCD) measures of mean blood flow velocity (MBFV) in the major cerebral arteries are associated with measures of lower extremity function in community-dwelling older adults. DESIGN: Cross-sectional study. SETTING: Community sample. PARTICIPANTS: Individuals aged 70 and older (mean 79.5, 54% female) without dementia participating in the Einstein Aging Study (N = 200)...
November 11, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29120400/fibrin-enhanced-canonical-wnt-signaling-directs-plasminogen-expression-in-cementoblasts
#7
Saeed Ur Rahman, Chan Ho Park, Jeong-Hwa Baek, Hyun-Mo Ryoo, Kyung Mi Woo
Cementum is a mineralized layer on the tooth's root surface and facilitates the biomechanical anchoring of fibrous connective tissues as a part of tooth-supportive complexes. Previously, we observed that OCCM30 cementoblasts cultured on fibrin matrices underwent apoptosis due to fibrin degradation through the expression of proteases. Here, we demonstrated that OCCM30 on fibrin matrices (OCCM30-fibrin) enhanced canonical Wnt signaling, which directed to plasminogen expression. The OCCM30-fibrin showed higher levels of Wnt3a expression, nuclear translocation of β-catenin, and T-cell factor (TCF) optimal motif (TOP) reporter activity than the cells on tissue culture dishes (OCCM30-TCD), indicating that the OCCM30-fibrin enhanced canonical Wnt/β-catenin signaling...
November 9, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29117957/nocturnal-oxyhemoglobin-desaturation-and-arteriopathy-in-a-pediatric-sickle-cell-disease-cohort
#8
Nomazulu Dlamini, Dawn E Saunders, Michael Bynevelt, Sara Trompeter, Timothy C Cox, Romola S Bucks, Fenella J Kirkham
OBJECTIVE: The purpose of this study of sickle cell disease (SCD) was to determine whether arteriopathy, measurable as intracranial vessel signal loss on magnetic resonance angiography (MRA), was associated with low nocturnal hemoglobin oxygen saturation (SpO2) or hemolytic rate, measurable as reticulocytosis or unconjugated hyperbilirubinemia. METHODS: Ninety-five East London children with SCD without prior stroke had overnight pulse oximetry, of whom 47 (26 boys, 39 hemoglobin SS; mean age 9...
November 8, 2017: Neurology
https://www.readbyqxmd.com/read/29117040/tcd-and-cerebral-circulatory-arrest-in-va-ecmo-patients
#9
Marinella Marinoni, Giovanni Cianchi, Sara Trapani, Maria L Migliaccio, Manuela Bonizzoli, Letizia Gucci, Antonella Cramaro, Andrea Gallerini, Fabio Picciafuochi, Serafina Valente, Adriano Peris
No abstract text is available yet for this article.
November 7, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29071967/-efficacy-of-modified-acupuncture-method-at-renying-st-9-for-patients-with-cervical-spondylosis-of-vertebral-artery-type-and-its-impact-on-velocity-of-cervical-blood-flow
#10
Xing-Hua Gui, Chao-Yang Ma, Lei Tang, Wen-Jun Wan, Yan-Fu Wang, Fen Xu, Shun-Yu Zhao
OBJECTIVE: To observe the clinical efficacy of modified acupuncture at Renying point (ST 9) for patients with cervical spondylosis of vertebral artery type and its influence on velocity of cervical blood flow. METHODS: Fifty-nine cases of vertebral artery type cervical spondylosis were randomly divided into control group (n=30) and treatment group (n=29). Both groups were acupunctured at ST 9, with routine acupuncture technique used in the control group and modified technique in the treatment group, respectively...
April 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29060618/automated-embolic-signal-detection-using-deep-convolutional-neural-network
#11
Praotasna Sombune, Phongphan Phienphanich, Sutanya Phuechpanpaisal, Sombat Muengtaweepongsa, Anuchit Ruamthanthong, Charturong Tantibundhit
This work investigated the potential of Deep Neural Network in detection of cerebral embolic signal (ES) from transcranial Doppler ultrasound (TCD). The resulting system is aimed to couple with TCD devices in diagnosing a risk of stroke in real-time with high accuracy. The Adaptive Gain Control (AGC) approach developed in our previous study is employed to capture suspected ESs in real-time. By using spectrograms of the same TCD signal dataset as that of our previous work as inputs and the same experimental setup, Deep Convolutional Neural Network (CNN), which can learn features while training, was investigated for its ability to bypass the traditional handcrafted feature extraction and selection process...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29057262/relationship-between-interferon-beta-1a-administration-and-intracranial-vascular-tone-regulation-in-patients-with-relapsing-remitting-multiple-sclerosis-a-pilot-study
#12
Vincenzo Dattola, Lilla Bonanno, Antonino Naro, Antonino Chillura, Anna Lisa Logiudice, Edoardo Sessa, Fausto Famà, Angelo Quartarone, Rocco Salvatore Calabrò, Silvia Marino, Margherita Russo
Interferon beta (IFN-β) therapy is one of the most commonly prescribed immunomodulatory therapies in relapsing-remitting multiple sclerosis (RRMS). A reversible cerebral vasoconstriction syndrome (RCVS), associated with IFN-β use, has been recently described. For this reason, we tested the effect of once a week intramuscular administration of IFN-β-1A on the function of cerebral vessels in a cohort of RRMS patients. Using transcranial Doppler (TCD) ultrasound, we measured the mean blood flow velocity (MFV) in intracranial vessels 10 h after IFN-β administration...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29056995/magnetic-resonance-imaging-and-clinical-outcome-in-patients-with-symptomatic-carotid-artery-stenosis-after-carotid-artery-revascularization
#13
Rafał Badacz, Anna Kabłak-Ziembicka, Małgorzata Urbańczyk-Zawadzka, Robert P Banyś, Piotr Musiałek, Piotr Odrowąż-Pieniążek, Mariusz Trystuła, Jan Ścigalski, Krzysztof Żmudka, Tadeusz Przewłocki
INTRODUCTION: About 30% of patients with carotid artery stenosis (CAS) develop dementia after a cerebral ischemic event (CIE), and 20-50% suffer from CIE recurrence during 6 months. Carotid artery revascularization (CAR) may prevent CIE recurrence, at the cost of new microembolic lesions (MES). The impact of CAR on cognitive function is debatable. AIM: To assess functional and cognitive outcome, cerebral flow on transcranial Doppler (TCD) and brain magnetic resonance imaging (MRI) in patients with symptomatic CAS referred for CAR...
2017: Postępy W Kardiologii Interwencyjnej, Advances in Interventional Cardiology
https://www.readbyqxmd.com/read/29056404/changes-in-transcranial-doppler-flow-velocities-in-children-with-sickle-cell-disease-the-impact-of-hydroxyurea-therapy
#14
Samuel Ademola Adegoke, Rejane de Souza Macedo-Campos, Josefina Aparecida Pellegrini Braga, Maria Stella Figueiredo, Gisele Sampaio Silva
BACKGROUND AND OBJECTIVES: Hydroxyurea (HU) was recently described as a substitute for chronic transfusion for children with sickle cell disease (SCD) and abnormal transcranial Doppler (TCD) velocities who have received at least 1 year of transfusions. However, the role of HU in reverting elevated TCD velocities in patients not treated with transfusion is still debatable. The objective of the study was to examine whether HU influences the progression of TCD velocities in children with SCD...
October 19, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29050524/transcranial-doppler-systolic-flow-index-and-icp-derived-cerebrovascular-reactivity-indices-in-tbi
#15
Frederick Adam Zeiler, Danilo Cardim, Joseph Donnelly, David Menon, Marek Czosnyka, Peter Smieleweski
To explore relationships between transcranial Doppler (TCD) indices of cerebrovascular reactivity and those derived from intracranial pressure (ICP). GOALS: A. Confirm previously described co-variance patterns of TCD/ICP indices, and B. Describe thresholds for Sx (correlation between systolic flow velocity (FVs) and cerebral perfusion pressure (CPP)) associated with outcome. Retrospective cohort of traumatic brain injury (TBI) patients: with TCD and ICP monitoring, we calculated various continuous indices of cerebrovascular reactivity: A...
October 19, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29048843/-analysis-of-hydrogen-isotopes-by-gas-chromatography-using-a-mncl2-coated-%C3%AE-al2o3-capillary-packed-column
#16
Ping Chen, Xiaolong Fu, Peng Hu, Chengjian Xiao, Xingbi Ren, Xiulong Xia, Heyi Wang
The conventional packed column gas chromatographic analysis of hydrogen isotopes has low column efficiency, broad peak and long retention time. In this work, a γ-Al2O3 with MnCl2 coated capillary packed column was tested at cryogenic temperature. The systematic column efficiency analysis and the hydrogen isotopes analytical technique research had been carried out. The results showed that, the γ-Al2O3 with MnCl2 coating could greatly improve the surface degree of order, pore structure and adsorption properties...
July 8, 2017: Se Pu, Chinese Journal of Chromatography
https://www.readbyqxmd.com/read/29043544/icp-versus-laser-doppler-cerebrovascular-reactivity-indices-to-assess-brain-autoregulatory-capacity
#17
F A Zeiler, J Donnelly, D Cardim, D K Menon, P Smielewski, M Czosnyka
BACKGROUND: To explore the relationship between various autoregulatory indices in order to determine which approximate small vessel/microvascular (MV) autoregulatory capacity most accurately. METHODS: Utilizing a retrospective cohort of traumatic brain injury patients (N = 41) with: transcranial Doppler (TCD), intracranial pressure (ICP) and cortical laser Doppler flowmetry (LDF), we calculated various continuous indices of autoregulation and cerebrovascular responsiveness: A...
October 17, 2017: Neurocritical Care
https://www.readbyqxmd.com/read/29034765/assessment-of-maternal-cerebral-blood-flow-velocity-by-transcranial-doppler-ultrasound-before-delivery-and-in-the-early-postpartum-period
#18
Hale Z Batur Caglayan, Bijen Nazliel, Mehmet Cinar, Esra Ataoglu, Ozlem Moraloglu, Ceyla Irkec
OBJECTIVE: This prospective observational study aimed to identify the effects of labor on cerebral hemodynamics by measuring the middle cerebral artery (MCA) blood flow velocity by transcranial Doppler ultrasound (TCD), and the related factors just before delivery and within the 24 h after delivery. METHODS: The study included 35 healthy pregnant women with a gestational age of >37 weeks who were in labor and a control group including healthy, age-matched, nonpregnant women (n = 24)...
October 16, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29030181/use-of-gelatin-and-gum-arabic-for-encapsulation-of-black-raspberry-anthocyanins-by-complex-coacervation
#19
Rezvan Shaddel, Javad Hesari, Sodeif Azadmard-Damirchi, Hamed Hamishehkar, Bahram Fathi-Achachlouei, Qingrong Huang
Protein-polysaccharide interactions offer opportunities for designing the new functional foods with applications in the food and pharmaceutical industries. In this work, we microencapsulated black raspberry water extracts by double emulsion technique prior to complex coacervation using gelatin and gum Arabic to diminish the instability of their anthocyanins (ANCs) as water soluble compounds, particularly under harsh processing and storage conditions. Subsequently, optical microscopy, moisture, hygroscopicity, solubility, particle size, loading capacity, zeta potential, color parameters (L*, a*, b*, C, H° and TCD), stability, Fourier transform infrared spectroscopy (FTIR), and thermal behavior were evaluated...
October 10, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29022123/assessment-of-a-closed-wash-system-developed-for-processing-living-donor-femoral-heads
#20
M J Eagle, J Man, P Rooney, T A McQuillan, G Galea, J N Kearney
NHS Blood and Transplant Tissue and Eye Services (TES) and Scottish National Blood Transfusion Services Tissues and Cells Directorate (TCD) currently bank whole, frozen femoral head bone from living donors who are undergoing primary hip replacement surgery. When required, the bone is issued to a surgeon still frozen on dry ice (- 79 °C). Consequently, the femoral head bone is not processed, is not sterilised and at the time of issue, it contains donor blood, bone marrow and associated cells. We have previously shown that, cut, shaped and washed bone from deceased donors can be processed to remove up to 99...
October 11, 2017: Cell and Tissue Banking
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