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Allergic rhinitis infant

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https://www.readbyqxmd.com/read/27880031/increased-levels-of-plasma-soluble-human-leukocyte-antigen-g-in-persistent-wheezy-infants
#1
Fulya Tahan, Hatice Eke Gungor, Himmet Haluk Akar, Berkay Saraymen
BACKGROUND: Human leukocyte antigen (HLA)-G is a non-classical major histocompatibility complex (MHC) class I antigen characterized by limited polymorphism in its coding region, unique tissue expression pattern in physiologic conditions and immunomodulatory properties. Recently, many studies suggest that the levels of sHLA-G were higher in atopic asthma and allergic rhinitis (AR). However, this remains to be uncertain in wheezy infants. In the present study, it was aimed to determine sHLA-G levels in wheezy infants...
November 23, 2016: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/27802847/a-multistrain-probiotic-formulation-attenuates-skin-symptoms-of-atopic-dermatitis-in-a-mouse-model-through-the-generation-of-cd4-foxp3-t-cells
#2
Joo-Hyun Shin, Myung-Jun Chung, Jae-Gu Seo
BACKGROUND: Atopic dermatitis (AD) is characterized by chronic inflammation of the skin. AD develops mainly in infants and young children. It induces skin disorders and signals the initiation of the allergic march including allergic asthma and rhinitis. Probiotics modify intestinal microbial populations in a beneficial way for human and animal hosts by reducing inflammatory cytokines. OBJECTIVE: As a result of their immunomodulatory properties, probiotics have been considered a promising therapeutic option for the prevention and treatment of AD...
2016: Food & Nutrition Research
https://www.readbyqxmd.com/read/27788565/polyunsaturated-fatty-acid-supplementation-in-infancy-for-the-prevention-of-allergy
#3
REVIEW
Tim Schindler, John Kh Sinn, David A Osborn
BACKGROUND: Early dietary intakes may influence the development of allergic disease. It is important to determine if dietary polyunsaturated fatty acids (PUFAs) given as supplements or added to infant formula prevent the development of allergy. OBJECTIVES: To determine the effect of higher PUFA intake during infancy to prevent allergic disease. SEARCH METHODS: We used the standard search strategy of the Cochrane Neonatal Review group to search the Cochrane Central Register of Controlled Trials (CENTRAL 2015, Issue 9), MEDLINE (1966 to 14 September 2015), EMBASE (1980 to 14 September 2015) and CINAHL (1982 to 14 September 2015)...
October 28, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27756492/repercussions-of-preterm-birth-on-symptoms-of-asthma-allergic-diseases-and-pulmonary-function-6-14-years-later
#4
C Gonçalves, G Wandalsen, F Lanza, A L Goulart, D Solé, A Dos Santos
BACKGROUND: Prevalence of allergic diseases and impaired pulmonary function may be high in children born prematurely. This study aimed to assess pulmonary function and prevalence of asthma, atopic diseases and allergic sensitisation in these patients. METHODS: A cross-sectional study was conducted with children aged 6-14 years who were born prematurely with birth weight <2000g from January 2008 to May 2011. Exclusion criteria were: major malformations, or acute respiratory disorders...
October 15, 2016: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/27698737/pediatric-rhinitis-risk-factors
#5
Yaofeng Ji, Yin Liu, Na Yang
Rhinitis is a common global disorder that impacts on the quality of life of the sufferer and caregivers. Treatment for pediatric rhinitis is empirical and does not include a detailed history of the allergy triggers or allergy testing. Thus, allergen avoidance advice is not tailored to the child's sensitivities, which may result in adenoid hypertrophy. However, infant onset rhinitis, especially its relationship with respiratory viruses, remains to be further clarified. Rhinitis basically involves inflammation of the upper nasal lining, presenting typically with symptoms of runny nose (rhinorrhea), nasal blockage, and/or sneezing...
October 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27608716/humidifier-disinfectant-lung-injury-how-do-we-approach-the-issues
#6
Jihyun Emma Choi PhD, Sang-Bum Hong Md PhD, Kyung-Hyun Do Md PhD, Hwa Jung Kim Md PhD, Seockhoon Chung Md PhD, Eun Lee Md PhD, Jihyun Choi, Soo-Jong Hong
A large portion of the Korean population has been exposed to toxic humidifier disinfectants, and considering that the majority of the victims are infants, the magnitude of the damage is expected to be considerably larger than what has currently been revealed. The current victims are voicing problems caused by various diseases, including but not limited to lung, upper respiratory tract, cardiovascular, kidney, musculoskeletal, eye, and skin diseases, etc. However, there has been difficulty in gaining validation for these health problems and identifying causal relationships due to lack of evidence proving that toxic humidifier disinfectant is the specific causes of extrapulmonary diseases such as allergic rhinitis...
August 29, 2016: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/27501330/early-polysensitisation-is-associated-to-allergic-multimorbidity-in-paris-birth-cohort-infants
#7
Stephan Gabet, Jocelyne Just, Rémy Couderc, Jean Bousquet, Nathalie Seta, Isabelle Momas
BACKGROUND: Profiles of allergic sensitisation are poorly documented in infancy. Relations between early sensitisation and allergic morbidity need to be clarified. METHODS: This study dealt with children involved in the Pollution and Asthma Risk: an Infant Study (PARIS), a population-based prospective birth cohort. Allergic sensitisation to 12 food and 4 inhalant allergens was assessed at 18 months and defined by a specific IgE level ≥ 0.35 kUA /L. Health data were collected by standardised questionnaires at 2 and 6 years...
August 8, 2016: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/27472490/following-up-infant-bronchiolitis-patients-provided-new-evidence-for-and-against-the-united-airway-disease-hypothesis
#8
Eero Lauhkonen, Petri Koponen, Kirsi Nuolivirta, Merja Helminen, Marita Paassilta, Jyri Toikka, Matti Korppi
AIM: The united airway disease (UAD) hypothesis suggests that allergic rhinitis and asthma develop together. We evaluated the evidence for and against the UAD hypothesis at five to seven years of age after hospitalisation for bronchiolitis at less than six months. METHODS: This study used prospective follow-up data for 102 children hospitalised for bronchiolitis under the age of six months. We included the presence of previous and current asthma, prolonged rhinitis and skin prick tests (SPT) to common inhaled allergens and lung function by impulse oscillometry (IOS) at five to seven years of age...
November 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27380601/probiotics-and-prebiotics-for-prevention-of-food-allergy-indications-and-recommendations-by-societies-and-institutions
#9
Sibylle Koletzko
Probiotics are defined as "live microorganisms that, when administered in adequate amounts, confer a health benefit on the host". Unfortunately, misuse of the term probiotic is very common. According to the regulation of the European food safety authority (EFSA) health claims on pre- and probiotics are not judged as favorable. Scientific societies should give guidance to the consumers and health care professionals on the use of probiotics and prebiotics for prevention and disease management. There is currently no positive recommendation from international scientific medical societies to use prebiotics or probiotics for treatment of food allergy or other allergic manifestations and for prevention of food allergy, allergic rhinitis, and asthma...
July 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27273433/study-of-the-atopic-march-development-of-atopic-comorbidities
#10
Lynda Schneider, Jon Hanifin, Mark Boguniewicz, Lawrence F Eichenfield, Jonathan M Spergel, Rada Dakovic, Amy S Paller
BACKGROUND: Atopic dermatitis (AD) is often the first step in the atopic march leading to the development of asthma or allergic rhinitis. The goal of this study was to determine whether early intervention with pimecrolimus limits the atopic march in infants with AD and to evaluate its efficacy and safety. METHODS: This was a 3-year double-blind study in which patients were randomized to pimecrolimus or vehicle and then open-label pimecrolimus for a planned further 3 years...
July 2016: Pediatric Dermatology
https://www.readbyqxmd.com/read/27225316/prenatal-fish-oil-supplementation-and-allergy-6-year-follow-up-of-a-randomized-controlled-trial
#11
Karen P Best, Thomas Sullivan, Debra Palmer, Michael Gold, Declan John Kennedy, James Martin, Maria Makrides
BACKGROUND AND OBJECTIVE: Evidence from randomized controlled trials in early infancy suggest that prenatal supplementation with Ω-3 (n-3) long-chain polyunsaturated fatty acids (LCPUFA) reduces the incidence of allergic disease characterized by an immunoglobulin E (IgE) response. We aimed to determine whether protective effects were evident in the 6-year-old offspring of women supplemented with n-3 rich fish oil during pregnancy. METHODS: Six-year follow-up of children (n = 706) with a family history of allergic disease from the Docosahexaenoic Acid to Optimize Mother Infant Outcome (DOMInO) trial...
June 2016: Pediatrics
https://www.readbyqxmd.com/read/27022267/allergic-diseases-among-children-nutritional-prevention-and-intervention
#12
REVIEW
Mohamed A Hendaus, Fatima A Jomha, Mohammad Ehlayel
Allergic diseases comprise a genetically heterogeneous group of chronic, immunomediated diseases. It has been clearly reported that the prevalence of these diseases has been on the rise for the last few decades, but at different rates, in various areas of the world. This paper discusses the epidemiology of allergic diseases among children and their negative impact on affected patients, their families, and societies. These effects include the adverse effects on quality of life and economic costs. Medical interest has shifted from tertiary or secondary prevention to primary prevention of these chronic diseases among high-risk infants in early life...
2016: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/26986820/-risk-factors-and-allergic-manifestations-associated-with-atopic-dermatitis-in-lom%C3%A3-togo-a-multicenter-study-of-476-children-aged-0-15-years
#13
J N Técléssou, A Mouhari-Toure, S Akakpo, S Bayaki, O B T Boukari, Y M Elégbédé, W Gnassingbé, K Kombaté, H Yédomon, P Pitché
OBJECTIVE: The aim of this study was to determine the prevalence and document the risk factors and allergic reactions associated with atopic dermatitis (AD) in children in Lomé. METHOD: This cross-sectional multicenter study took place from March to June 2013 in four health facilities in Lomé. It applied the criteria of the United Kingdom Working Party (UKWP). RESULTS: We included 476 children aged 0-15 years who came for a vaccination or pediatric consultation; 31...
January 2016: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/26954777/the-adapar-birth-cohort-study-food-allergy-results-at-five-years-and-new-insights
#14
Dilek Doğruel, Gülbin Bingöl, Mustafa Yılmaz, Derya Ufuk Altıntaş
BACKGROUND: Although food allergy (FA) is often a transient condition during childhood, when and in whom FA will resolve can be affected by many factors. In this study, we analyzed the data at 5 years on 33 children diagnosed with FA in the ADAPAR (Adana Pediatric Allergy Research) birth cohort study in southern Turkey. METHODS: Thirty-three infants detected as having FA at the end of their first year in the ADAPAR study were assessed every 6 months until the age of 5 years...
2016: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/26757832/maternal-diet-during-pregnancy-and-lactation-and-cow-s-milk-allergy-in-offspring
#15
J Tuokkola, P Luukkainen, H Tapanainen, M Kaila, O Vaarala, M G Kenward, L J Virta, R Veijola, O Simell, J Ilonen, M Knip, S M Virtanen
BACKGROUND/OBJECTIVES: Diet during pregnancy and lactation may have a role in the development of allergic diseases. There are few human studies on the topic, especially focusing on food allergies. We sought to study the associations between maternal diet during pregnancy and lactation and cow's milk allergy (CMA) in offspring. SUBJECTS/METHODS: A population-based birth cohort with human leukocyte antigen-conferred susceptibility to type 1 diabetes was recruited in Finland between 1997 and 2004 (n=6288)...
May 2016: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/26689229/probiotics-for-allergy-prevention
#16
C E West
Probiotics, given either as a supplement or in infant foods, have been evaluated in randomised controlled trials for allergy prevention. Here, the aim is to give an overview of the results from these primary prevention studies and to discuss current strategies. In most studies, single strains or a mixture of strains of lactic acid bacteria and bifidobacteria have been used--prenatally, postnatally or perinatally. Several meta-analyses have reported a moderate benefit of probiotics for eczema prevention, and the most consistent effect has been observed with a combined perinatal intervention in infants at high risk of allergic disease due to familial predisposition...
2016: Beneficial Microbes
https://www.readbyqxmd.com/read/26664574/clinical-phenotype-and-allergen-sensitization-in-the-first-2%C3%A2-years-as-predictors-of-atopic-disorders-at-age-5%C3%A2-years
#17
Phaik Ling Quah, Evelyn Xiu Ling Loo, Gabriella Nadine Li Yuan Lee, I-Chun Kuo, Irvin Gerez, Genevieve Villablanca Llanora, Yiong Huak Chan, Marion Aw, Lynette Pei-Chi Shek, Bee Wah Lee
INTRODUCTION: From a birth cohort of at-risk Asian infants, we prospectively investigated the role of early onset allergen sensitization and clinical phenotypes as risk factors for atopic disorders at the age of 5 years. METHODS AND MATERIALS: The study recruited 253 families with a history of allergic disease in a first degree relative from an antenatal clinic in Singapore. The children were followed prospectively to assess clinical outcomes and skin prick test was performed at 2 and 5 years of age...
2015: World Allergy Organization Journal
https://www.readbyqxmd.com/read/26657170/recurrent-wheezing-and-asthma-after-bocavirus-bronchiolitis
#18
T Del Rosal, M L García-García, C Calvo, F Gozalo, F Pozo, I Casas
BACKGROUND: Human bocavirus (HBoV) was recently discovered and identified as an important cause of respiratory infection in young children. However, the relationship between HBoV-bronchiolitis and the development of recurrent wheezing has not yet been established. OBJECTIVE: We designed this study in order to describe the mid-term outcome, regarding the development of recurrent wheezing and asthma of HBoV-bronchiolitis patients and to compare it with RSV-bronchiolitis infants...
September 2016: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/26552773/clinical-features-of-eosinophilic-esophagitis-in-children-and-adults
#19
REVIEW
Stephan Miehlke
Eosinophilic esophagitis (EoE) may affect humans at any age with a predominance for Caucasian males. The clinical manifestation of EoE varies depending on the patient's age. Infants and young children may primarily present with unspecific symptoms such as feeding problems, vomiting and abdominal pain. In adolescents and adults, dysphagia and food impactation become the predominant symptoms. EoE should also be considered in cases of refractory heartburn in both children and adults. Concomitant allergic diseases such as asthma, rhinitis and eczema, as well as peripheral eosinophilia and elevated total serum IgE values are common in pediatric and adult EoE patients...
October 2015: Best Practice & Research. Clinical Gastroenterology
https://www.readbyqxmd.com/read/26244900/the-additional-cost-burden-of-preexisting-medical-conditions-during-pregnancy-and-childbirth
#20
COMPARATIVE STUDY
Amy Law, Mark McCoy, Richard Lynen, Suellen M Curkendall, Justin Gatwood, Paul L Juneau, Pamela Landsman-Blumberg
OBJECTIVES: To identify the prevalence of comorbidities in pregnant women and examine the incremental costs of these conditions on the care for mothers and their newborns. METHODS: This was a retrospective comparative cohort study of women ages 15-49 years with a documented live-birth delivery using de-identified claims from the MarketScan Research Commercial Claims and Encounters database incurred between January 1, 2007, and December 31, 2011. Total health care costs from date of first pregnancy-related claim through 3 months postdelivery were reported; pregnancy-related comorbidities prior to the pregnancy diagnosis were identified and categorized in the 12 months prior to the pregnancy diagnosis, and costs associated with each condition were compiled...
November 2015: Journal of Women's Health
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