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https://www.readbyqxmd.com/read/28231596/-impact-of-a-senso-motoric-intervention-in-copd-patients-participating-in-an-outpatient-pulmonary-rehabilitation-program-a-randomized-controlled-trial
#1
M Spielmanns, K Müller, N Schott, A Winkler, H Polanski, C Nell, T Boeselt, A R Koczulla, J H Storre, W Windisch, F S Magnet, K Baum
Objective: Exercise training provides a cornerstone of pulmonary rehabilitation (PR) in COPD-patients. However, the components of the training are not yet fully investigated. We conducted a randomized controlled trial to investigate the effectiveness of a sensory-motoric training (SMT) in comparison to a conventional strength training (KT) according to the physical performance. Patients and Methods: 43 COPD patients were randomized and participated either in the intervention group (SMT = 30 minutes SMT per day) or in the control group (KT = 30 minutes KT per day)...
February 23, 2017: Die Rehabilitation
https://www.readbyqxmd.com/read/28231336/comparison-of-neurological-health-outcomes-between-two-adolescent-cohorts-exposed-to-pesticides-in-egypt
#2
Ahmed A Ismail, Matthew R Bonner, Olfat Hendy, Gaafar Abdel Rasoul, Kai Wang, James R Olson, Diane S Rohlman
Pesticide-exposed adolescents may have a higher risk of neurotoxic effects because of their developing brains and bodies. However, only a limited number of studies have addressed this risk among adolescents. The aim of this study was to compare neurological outcomes from two cohorts of Egyptian adolescents working as pesticide applicators. In 2005 and 2009, two cohorts of male adolescents working as pesticide applicators for the cotton crop were recruited from Menoufia Governorate, Egypt. The same application schedule and pesticides were used at both times, including both organophosphorus, and pyrethroid compounds...
2017: PloS One
https://www.readbyqxmd.com/read/28231258/depressive-symptoms-in-hiv-infected-and-seronegative-control-subjects-in-cameroon-effect-of-age-education-and-gender
#3
Georgette D Kanmogne, Fang Qiu, Félicien E Ntone, Julius Y Fonsah, Dora M Njamnshi, Callixte T Kuate, Roland F Doh, Anne M Kengne, Claude T Tagny, Emilienne Nchindap, Léopoldine Kenmogne, Dora Mbanya, Mariana Cherner, Robert K Heaton, Alfred K Njamnshi
Depression is a leading cause of HIV/AIDS disease burden; it worsens health outcomes and quality of life. Addressing this problem requires accurate quantification of the extra burden of depression to HIV/AIDS in a given population, and knowledge of the baseline depression prevalence in the general population. There has been no previous study of depression in the general Cameroonian population. The current study attempts to address that important need. We used the Beck Depression Inventory-II to assess the prevalence and severity of depressive symptoms in 270 HIV-infected and seronegative Cameroonians...
2017: PloS One
https://www.readbyqxmd.com/read/28231069/the-potential-of-transcranial-photobiomodulation-therapy-for-treatment-of-major-depressive-disorder
#4
Farzad Salehpour, Seyed Hossein Rasta
Major depressive disorder is a common debilitating mood disorder that affects quality of life. Prefrontal cortex abnormalities, an imbalance in neurotransmitters, neuroinflammation, and mitochondrial dysfunction are the major factors in the etiology of major depressive disorder. Despite the efficacy of pharmacotherapy in the treatment of major depressive disorder, 30%-40% of patients do not respond to antidepressants. Given this, exploring the alternative therapies for treatment or prevention of major depressive disorder has aroused interest among scientists...
February 23, 2017: Reviews in the Neurosciences
https://www.readbyqxmd.com/read/28231027/insomnia-sleep-quality-and-quality-of-life-in-mild-to-moderate-parkinson-s-disease
#5
Shirin Shafazand, Douglas M Wallace, Kristopher L Arheart, Silvia Vargas, Corneliu C Luca, Henry Moore, Heather Katzen, Bonnie Levin, Carlos Singer
RATIONALE: Sleep disorders are prevalent in Parkinson's disease and yet under reported in clinical settings. The contribution of sleep disorders to health-related quality of life (HRQOL) for patients with this degenerative neurological disease are not well known. OBJECTIVES: To evaluate the impact of insomnia symptoms, obstructive sleep apnea (OSA), and poor sleep quality on HRQOL in a cohort of patients with idiopathic Parkinson's disease. METHODS: We enrolled a convenience sample of 66 adults seen in the University of Miami Movement Disorders Clinic between July 2011 and June 2013...
February 23, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28231005/synaptic-plasticity-selectively-activated-by-polarization-dependent-energy-efficient-ion-migration-in-an-ultrathin-ferroelectric-tunnel-junction
#6
Chansoo Yoon, Ji Hye Lee, Sangik Lee, Ji Hoon Jeon, Jun Tae Jang, Dae Hwan Kim, Young Heon Kim, Bae Ho Park
Selectively activated inorganic synaptic devices, showing a high on/off ratio, ultrasmall dimensions, low power consumption, and short programming time, are required to emulate the functions of high-capacity and energy-efficient reconfigurable human neural systems combining information storage and processing ( Li et al. Sci. Rep. 2014 , 4 , 4096 ). Here, we demonstrate that such a synaptic device is realized using a Ag/PbZr0.52Ti0.48O3 (PZT)/La0.8Sr0.2MnO3 (LSMO) ferroelectric tunnel junction (FTJ) with ultrathin PZT (thickness of ∼4 nm)...
February 24, 2017: Nano Letters
https://www.readbyqxmd.com/read/28230899/shared-care-across-the-interface-between-primary-and-specialty-care-in-management-of-long-term-conditions
#7
REVIEW
Susan M Smith, Gráinne Cousins, Barbara Clyne, Shane Allwright, Tom O'Dowd
BACKGROUND: Shared care has been used in the management of many chronic conditions with the assumption that it delivers better care than primary or specialty care alone; however, little is known about the effectiveness of shared care. OBJECTIVES: To determine the effectiveness of shared care health service interventions designed to improve the management of chronic disease across the primary/specialty care interface. This is an update of a previously published review...
February 23, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28230732/effects-of-acute-blueberry-flavonoids-on-mood-in-children-and-young-adults
#8
Sundus Khalid, Katie L Barfoot, Gabrielle May, Daniel J Lamport, Shirley A Reynolds, Claire M Williams
Epidemiological evidence suggests that consumption of flavonoids (usually via fruits and vegetables) is associated with decreased risk of developing depression. One plausible explanation for this association is the well-documented beneficial effects of flavonoids on executive function (EF). Impaired EF is linked to cognitive processes (e.g., rumination) that maintain depression and low mood; therefore, improved EF may reduce depressionogenic cognitive processes and improve mood. Study 1: 21 young adults (18-21 years old) consumed a flavonoid-rich blueberry drink and a matched placebo in a counterbalanced cross-over design...
February 20, 2017: Nutrients
https://www.readbyqxmd.com/read/28230602/subcutaneous-c-shape-muscular-flap-for-correcting-the-depression-of-alar-base-in-affected-side-in-patients-with-unilateral-complete-cleft-lip-palate-during-primary-surgery
#9
Dandan Wu, Guomin Wang, Ningjuan Ouyang, Yuhen Lin, Yang Chen, Jiewen Dai
PURPOSE: The depression of alar base in affected side in patients with unilateral complete cleft lip/palate (CL/P) is one of common clinical features. In this study, the authors try to explore the effect of subcutaneous C shape muscular flap for correcting the depression of alar base in affected side in patients with unilateral complete CL/P during primary surgery. METHODS: A total of 30 patients with unilateral complete CL/P who received primary correction of the lip nose deformity were included in this study...
February 22, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28230414/the-effect-of-cognitive-behavioral-therapy-as-an-antidepressive-treatment-is-falling-reply-to-lj%C3%A3-tsson-et-al-2017-and-cristea-et-al-2017
#10
Oddgeir Friborg, Tom J Johnsen
This article critically reassesses the nonlinear reanalysis by Ljótsson, Hedman, Mattsson, and Andersson (2017) and reviews Cristea et al.'s (2017) extension of our original meta-analysis (Johnsen & Friborg, 2015) reporting a decline in the effects of cognitive-behavioral therapy (CBT) for treating unipolar depression. Ljótsson et al. fitted a piecewise meta-regression model to the data, indicating a halt in the decline from the year 1995 onward, hence concluding that CBT is not gradually losing its efficacy...
March 2017: Psychological Bulletin
https://www.readbyqxmd.com/read/28230413/the-effects-of-cognitive-behavioral-therapy-are-not-systematically-falling-a-revision-of-johnsen-and-friborg-2015
#11
Ioana A Cristea, Simona Stefan, Eirini Karyotaki, Daniel David, Steven D Hollon, Pim Cuijpers
In a meta-analysis, Johnsen and Friborg (2015) reported a significant negative relationship between publication year and the effect sizes (ESs) of cognitive-behavioral therapy (CBT) for depressive disorders, suggesting its effectiveness was falling. We identified a series of methodological and conceptual caveats and consequently redid the meta-analysis. We used the same inclusion criteria, but only included randomized controlled trials and searched for additional eligible trials. We computed both within-group and between-group ESs for the CBT arm for the Beck Depression Inventory (BDI) and the Hamilton Rating Scale for Depression (HRSD)...
March 2017: Psychological Bulletin
https://www.readbyqxmd.com/read/28230412/the-effects-of-cognitive-behavioral-therapy-for-depression-are-not-falling-a-re-analysis-of-johnsen-and-friborg-2015
#12
Brjánn Ljótsson, Erik Hedman, Simon Mattsson, Erik Andersson
Cognitive-behavioral therapy (CBT) has a solid evidence base as an effective treatment for depression. However, a recent meta-analysis (Johnsen & Friborg, 2015) including 70 studies, showed that the effect sizes of CBT for depression have been falling between 1977 and 2014. A possible important limitation in the Johnsen and Friborg (2015) study was that they did not investigate a leveling off in the decline over time of the effectiveness of CBT for depression. We therefore reanalyzed the data reported by Johnsen and Friborg (2015) using meta-analytic regression models that allowed for a curvilinear effect of publication year and also modeled separate estimates of the decline of treatment effect before and after 1995...
March 2017: Psychological Bulletin
https://www.readbyqxmd.com/read/28230409/using-the-center-for-epidemiologic-studies-depression-scale-to-assess-depression-in-women-with-hiv-and-women-at-risk-for-hiv-are-somatic-items-invariant
#13
Leah M Adams, Tracey E Wilson, Daniel Merenstein, Joel Milam, Jennifer Cohen, Elizabeth T Golub, Adebola Adedimeji, Judith A Cook
The prevalence of depression among women living with HIV/AIDS is elevated, compared with women in the general population and men diagnosed with HIV/AIDS. Although symptoms of HIV may overlap with somatic symptoms of depression, little research has explored how well screening tools accurately assess depression rather than symptoms of HIV/AIDS among women. The present study examined the utility of a widely used tool for assessing depression symptoms among women living with HIV/AIDS. Data are from the Women's Interagency HIV Study (WIHS), a multisite, longitudinal cohort study of women living with HIV/AIDS (n = 1,329) and seronegative women (n = 541) matched on key risk factors for HIV/AIDS...
February 23, 2017: Psychological Assessment
https://www.readbyqxmd.com/read/28230401/maternal-depression-and-parenting-in-early-childhood-contextual-influence-of-marital-quality-and-social-support-in-two-samples
#14
Lindsay Taraban, Daniel S Shaw, Leslie D Leve, Melvin N Wilson, Thomas J Dishion, Misaki N Natsuaki, Jenae M Neiderhiser, David Reiss
Marital quality and social support satisfaction were tested as moderators of the association between maternal depressive symptoms and parenting during early childhood (18-36 months) among 2 large, divergent, longitudinal samples (n = 526; n = 570). Unexpectedly, in both samples the association between maternal depressive symptoms and reduced parenting quality was strongest in the context of high marital quality and high social support, and largely nonsignificant in the context of low marital quality and low social support...
March 2017: Developmental Psychology
https://www.readbyqxmd.com/read/28230391/improvements-in-emotion-regulation-following-mindfulness-meditation-effects-on-depressive-symptoms-and-perceived-stress-in-younger-breast-cancer-survivors
#15
Chloe C Boyle, Annette L Stanton, Patricia A Ganz, Catherine M Crespi, Julienne E Bower
OBJECTIVE: Mindfulness meditation reduces psychological distress among individuals with cancer. However, mechanisms for intervention effects have not been fully determined. This study tested emotion regulation strategies as mediators of intervention effects in a sample of younger women treated for breast cancer, a group at risk for psychological distress. We focused on two distinct strategies targeted by the intervention-rumination and self-kindness-and further examined the broader construct of mindfulness as a potential mediator...
February 23, 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28230390/effectiveness-of-an-internet-intervention-deprexis-for-depression-in-a-united-states-adult-sample-a-parallel-group-pragmatic-randomized-controlled-trial
#16
Christopher G Beevers, Rahel Pearson, James S Hoffman, A Alban Foulser, Jason Shumake, Björn Meyer
OBJECTIVE: To examine the effectiveness of an Internet intervention for depression with a randomized, controlled trial in a large sample of adults recruited from the United States. METHOD: The current study examines the effectiveness of Deprexis, an Internet treatment for depression that was provided with relatively minimal support. There were 376 treatment-seeking adults (mean age = 32 years; 74% female; 77% Caucasian, 7% Asian, 7% multiple races, 4% African American, and 11% Hispanic/Latino) with elevated depression (Quick Inventory of Depressive Symptoms-Self-Report [QIDS-SR] > = 10) who were randomized to receive an 8-week course of treatment immediately (n = 285) or after an 8-week delay (n = 91; i...
February 23, 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28230331/the-development-and-assessment-of-the-worry-about-pain-questionnaire
#17
J C Lefebvre, M P Jensen, S J Waters, I R Molton, F J Keefe, D S Caldwell
BACKGROUND: Worry can be conceptualized as a cognitive-affective automatic process initiated in order to address uncertainty and potential personal inadequacies that could result in negative outcomes. The purpose of the current study was to develop a measure of pain-specific worry - the Worry About Pain Questionnaire (WAPQ). METHOD: In study 1, responses of 335 pain-free participants were used to complete an item analysis and exploratory factors analysis to develop and assess the internal structure of the WAPQ...
February 23, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28230263/recent-advances-in-%C3%AE-aminobutyric-acid-gaba-properties-in-pulses-an-overview
#18
REVIEW
Nooshin Nikmaram, B N Dar, Shahin Roohinejad, Mohamed Koubaa, Francisco J Barba, Greiner Ralf, Stuart K Johnson
Beans, peas, and lentils are all types of pulses that are extensively used as foods around the world due to their beneficial effects on human health including their low glycemic index, cholesterol lowering effects, ability to decrease the risk of heart diseases and their protective effects against some cancers. These health benefits are a result of their components such as bioactive proteins, dietary fibers, slowly digested starches, minerals and vitamins, and bioactive compounds. Among these bioactive compounds, γ-aminobutyric acid (GABA), a non-proteinogenic amino acid with numerous reported health benefits (e...
February 23, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28230173/a-novel-physiological-role-for-cardiac-myoglobin-in-lipid-metabolism
#19
Ulrike B Hendgen-Cotta, Sonja Esfeld, Cristina Coman, Robert Ahrends, Ludger Klein-Hitpass, Ulrich Flögel, Tienush Rassaf, Matthias Totzeck
Continuous contractile activity of the heart is essential and the required energy is mostly provided by fatty acid (FA) oxidation. Myocardial lipid accumulation can lead to pathological responses, however the underlying mechanisms remain elusive. The role of myoglobin in dioxygen binding in cardiomyocytes and oxidative skeletal muscle has widely been appreciated. Our recent work established myoglobin as a protector of cardiac function in hypoxia and disease states. We here unravel a novel role of cardiac myoglobin in governing FA metabolism to ensure the physiological energy production through β-oxidation, preventing myocardial lipid accumulation and preserving cardiac functions...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28230172/evidence-for-critical-role-of-lymphocyte-cytosolic-protein-1-in-oral-cancer
#20
Nao Koide, Atsushi Kasamatsu, Yosuke Endo-Sakamoto, Sho Ishida, Toshihiro Shimizu, Yasushi Kimura, Isao Miyamoto, Shusaku Yoshimura, Masashi Shiiba, Hideki Tanzawa, Katsuhiro Uzawa
Lymphocyte cytosolic protein 1 (LCP1), a member of actin-binding protein of the plastin family, has been identified in several malignant tumors of non-hematopoietic sites, such as the colon, prostate, and breast. However, little is known about the roles of LCP1 in oral squamous cell carcinomas (OSCCs). This present study sought to clarify the clinical relevance of LCP1 in OSCCs and investigate possible clinical applications for treating OSCCs by regulating LCP1 expression. We found up-regulation of LCP1in OSCCs compared with normal counterparts using real-time quantitative reverse transcription polymerase chain reaction (qRT-PCR), immunoblotting, and immunohistochemistry (P < 0...
February 23, 2017: Scientific Reports
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