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Swallowing disorders

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https://www.readbyqxmd.com/read/29774515/eating-disorder-or-oesophageal-achalasia-during-adolescence-diagnostic-difficulties
#1
REVIEW
Aurélie Letranchant, Bénédicte Pigneur, Martine Flament, Nathalie Godart
Marine was a fourteen and a half-year-old adolescent female hospitalized for an eating disorder (ED) of the anorexic type with purging behaviors. She has had a complicated life course, made up of disruptions and discontinuities, both family and school. Since the age of five, Marine had been intermittently treated in psychiatry for a diagnosis of oppositional defiant disorder. The current illness started with spontaneous and induced vomiting associated with major weight loss (body mass index, 15.27 kg m-2 )...
May 17, 2018: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/29769252/frequency-of-non-motor-symptoms-in-parkinson-s-disease-presenting-to-tertiary-care-centre-in-pakistan-an-observational-cross-sectional-study
#2
Shahid Mukhtar, Rashid Imran, Mohsin Zaheer, Huma Tariq
OBJECTIVE: To determine the frequency of non-motor symptoms (NMS) in patients of Parkinson's disease (PD) presenting to a movement disorder clinic at a tertiary care centre in Pakistan, and how frequency of NMS is different in male and female patients. STUDY DESIGN: Observational, cross-sectional study. SETTING: Tertiary care centre. PARTICIPANTS: Out of 102 patients, 85 were included. Inclusion criteria were patients with PD diagnosed according to the UK Parkinson's Disease Society Brain Bank Clinical Diagnostic Criteria, age ≥18 years, able to give consent and have no difficulty in answering questions...
May 16, 2018: BMJ Open
https://www.readbyqxmd.com/read/29769121/anxiety-and-depression-in-primary-sj%C3%A3-gren-s-syndrome-a-cross-sectional-study
#3
Yafei Cui, Ling Xia, Lin Li, Qian Zhao, Shengnan Chen, Zhifeng Gu
BACKGROUND: Prevalence of anxiety and depression is high in people with Primary Sjögren's syndrome (pSS). However, there are currently no known reported studies about anxiety/depression in pSS patients from China. Our aim was to compare anxiety/depression in pSS patients and healthy controls; to investigate the prevalence of anxiety and/or depression among pSS patients in China; to evaluate its relationship with the disease activity, fatigue, pain, education, ocular surface disease, oral health, swallowing disorders, employment status, European League Against Rheumatism Sjögren's Syndrome Patient Reported Index(ESSPRI) as well as to analyze potential determinants of anxiety and depression...
May 16, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29765891/botulinum-toxin-injection-in-the-treatment-of-postextubation-dysphagia-a-case-report
#4
Byung Wook Kim, Hee-Ju Kim, Jung Keun Hyun, Seo Young Kim, Tae Uk Kim
Prolonged intubation is known to bring on postextubation dysphagia (PED) in some patients. We have noted that there were some studies to investigate specific type and pattern of PED, which showed large variety of different swallowing abnormalities as mechanisms of PED that are multifactorial. There are several options of treatment in accordance with the management of these abnormalities. A botulinum toxin (BoT) injection into the upper esophageal sphincter (UES) can improve swallowing functions for patients with this disorder, by working to help the muscle relax...
April 2018: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29753584/a-novel-fluoroscopic-method-for-multidimensional-evaluation-of-swallowing-function
#5
Nobuyuki Arai, Kozo Hanayama, Takaharu Yamazaki, Tetsuya Tomita, Akio Tsubahara, Kazuomi Sugamoto
OBJECTIVE: Dynamic videofluoroscopic swallow study (VFSS) is used to investigate swallowing movements. However, it requires prolonged radiation exposure and mainly provides qualitative information. Herein, we present a multi-dimensional method for analyzing swallowing based on a pulsed, low-dose fluoroscopy technique that uses serial-shot images and evaluates the size, position, and temporal profile of the bolus to obtain a more comprehensive and realistic analysis of swallowing movements...
May 9, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29746402/update-in-therapeutic-strategies-for-parkinson-s-disease
#6
Jaime Kulisevsky, Lais Oliveira, Susan H Fox
PURPOSE OF REVIEW: To review recent advances in therapeutics for motor and nonmotor symptoms of Parkinson's disease. RECENT FINDINGS: Neuroprotection remains a large area of investigation with preliminary safety data on alpha synuclein immunotherapy and glucagon-like peptide-1 agonists. Novel Monoamine Oxidase B and Caetchol-O-methyltransferase-inhibitors for motor fluctuations have shown benefit and are recently approved for clinical use. Long-acting amantadine has also been approved to reduce dyskinesia...
May 8, 2018: Current Opinion in Neurology
https://www.readbyqxmd.com/read/29737732/-clinical-analysis-of-arytenoid-cartilage-reposition-with-snake-mouth-forceps-for-the-arytenoid-cartilage-dislocation
#7
Qing Xiang Zhang, Shuang Ba He, Zi Gang Che, Hui Ying Hu, Ya Qun Liu, Yuan Yuan Lu, Zhen Kun Yu
OBJECTIVES: To investigate the clinical effect of the arytenoid cartilage reposition using snake mouth reduction forceps under general anesthesia. METHODS: Data of twenty-six cases accepted arytenoid cartilage reposition under intravenous general anesthesia were analyzed, nineteen cases accepted laryngeal CT scan and cricoarytenoid joint reconstruction, all patients underwent endolaryngeal muscle electromyography examination. According to the position of cartilage dislocation prompted by laryngoscope and CT, the arytenoid cartilage was repositoned under the visual laryngoscope using special snake mouth reduction forceps...
March 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29736223/the-effect-of-swallowing-rehabilitation-on-quality-of-life-of-the-dysphagic-patients-with-cortical-ischemic-stroke
#8
Kadir Bahcecı, Ebru Umay, Ibrahim Gundogdu, Eda Gurcay, Erhan Ozturk, Sibel Alıcura
Background: Swallowing and swallowing-related quality of life studies following stroke were almost always performed by including both patients with brainstem and cortical involvement. It was aimed in this study to show the presence of dysphagia in patients with only cortical ischemic stroke and to investigate the interaction between dysphagia and quality of life as well as to evaluate the effect of a rehabilitation program in the acute phase. Methods: Seventy-two patients with cortical stroke (between 0 and 30 days) and dysphagia were included...
October 7, 2017: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/29731889/swallowing-disorder-following-salvage-total-pharyngo-laryngo-esophagectomy-with-free-jejunum-reconstruction
#9
Takashi Maruo, Minoru Sakuraba, Takeshi Shinozaki, Toshifumi Tomioka, Wataru Okano, Satoko Arahira, Yoshie Iino, Ryuichi Hayashi
For recurrent cases or residual cases following concomitant chemo-radiation therapy (CCRT), salvage surgery is a frequently used treatment options. A swallowing disorder is one of the major complications of CCRT. The purpose of the present study was to evaluate the effect of CCRT on swallowing function in patients who underwent salvage total pharyngo-laryngo-esophagectomy (TPLE), and to evaluate the importance of pharyngeal constriction in patients who underwent TPLE. Between 2008 January and 2014 May, 54 patients were treated with salvage TPLE following CCRT or TPLE at the National Cancer Center Hospital East, Chiba, Japan and were included in the present study...
May 2018: Oncology Letters
https://www.readbyqxmd.com/read/29727486/reliability-and-validity-of-the-karaduman-chewing-performance-scale-in-pediatric-neuromuscular-diseases-a-system-for-classification-of-chewing-disorders
#10
Selen Serel Arslan, Güllü Aydın, İpek Alemdaroğlu, Öznur Tunca Yılmaz, Aynur Ayşe Karaduman
BACKGROUND: Chewing disorders can be seen in children with Neuromuscular Diseases (NMDs), which may cause swallowing difficulties like choking, retching, food stuck feeling in the throat. Due to these effects, it is important to determine chewing disorders early with appropriate assessment methods to plan appropriate therapies in NMDs. OBJECTIVE(S: The aim of this study was to investigate reliability and validity of the Karaduman Chewing Performance Scale (KCPS) in children with NMDs...
May 4, 2018: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/29726748/efficacy-of-neuromuscular-electrical-stimulation-in-improving-the-negative-psychological-state-in-patients-with-cerebral-infarction-and-dysphagia
#11
Yanfang Zeng, James Yip, Hongli Cui, Longfei Guan, Haomeng Zhu, Weidong Zhang, Huishan Du, Xiaokun Geng
Objective To observe the improvement of negative affect disorders in patients with cerebral infarction and dysphagia by neuromuscular electrical stimulation. Methods One hundred and twelve patients with cerebral infarction and dysphagia were selected and randomized into treatment (n = 59) and control (n = 53) groups. Similar swallowing function was found in both groups before treatment: (1) Water-drinking test in the treatment group proved swallowing function Level III in 24 cases, Level IV in 22 cases and Level V in 13 cases; (2) in the control group, swallowing function was Level III in 21 cases, Level IV in 20 cases and Level V in 12 cases...
May 4, 2018: Neurological Research
https://www.readbyqxmd.com/read/29724130/elucidating-inconsistencies-in-dysphagia-diagnostics-redefining-normal
#12
Emily K Plowman, Ianessa A Humbert
Speech-language pathologists (SLPs) are the primary healthcare providers responsible for the evaluation and treatment of dysphagia. Fundamental to this role is the ability to make accurate clinical judgements to distinguish between normal versus disordered swallowing for subsequent treatment planning. In this review, we highlight recent data collected from practising clinicians in the USA that reveal low levels of agreement across clinicians and poor to moderate levels of accuracy for making binary diagnostic ratings (normal vs...
May 3, 2018: International Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/29720801/spinocerebellar-ataxia-21-in-a-turkish-child
#13
Faruk Incecik, Ozlem M Herguner, Patrick Willems, Neslihan O Mungan
Hereditary cerebellar ataxias are genetically heterogeneous disorders. Autosomal recessive spinocerebellar ataxia-21 (SCAR21) is a neurologic disorder characterized by the onset of cerebellar ataxia, recurrent episodes of liver failure, peripheral neuropathy, and learning disabilities. Herein, we reported a case presented with gait and balance problems, swallowing difficulties, mild delayed motor development, and mild learning disability with SCAR21 that confirmed by mutation analysis in a Turkish child. To the best of our knowledge, this is the first case of SCAR21 from Turkey...
January 2018: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/29720344/-the-sense-of-taste-in-a-clinical-setting
#14
Alexander Fjaeldstad, Henrique Fernandes, Jens Randel Nyengaard, Therese Ovesen
As a gatekeeper, taste buds forage chemicals to identify both nutrition and toxins. This can be the decisive difference between initiating the swallow reflex or spitting out the oral contents. In addition to this simple function the sense of taste takes part in more complex relations such as reflexes vs learning, perception vs expectation, and pleasure vs disgust. All relations, which can be perturbed into unbalance, create great discomfort in patients suffering from a dysfunctional sense of taste. This review discusses the most important mechanisms of taste function and dysfunction as well as the possible avenues for treatment of the disorders...
April 30, 2018: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/29716267/magnetic-resonance-imaging-based-anatomical-assessment-of-tongue-impairment-due-to-amyotrophic-lateral-sclerosis-a-preliminary-study
#15
Euna Lee, Fangxu Xing, Sung Ahn, Timothy G Reese, Ruopeng Wang, Jordan R Green, Nazem Atassi, Van J Wedeen, Georges El Fakhri, Jonghye Woo
Amyotrophic Lateral Sclerosis (ALS) is a neurological disorder, which impairs tongue function for speech and swallowing. A widely used Diffusion Tensor Imaging (DTI) analysis pipeline is employed for quantifying differences in tongue fiber myoarchitecture between controls and ALS patients. This pipeline uses both high-resolution magnetic resonance imaging (hMRI) and DTI. hMRI is used to delineate tongue muscles, while DTI provides indices to reveal fiber connectivity within and between muscles. The preliminary results using five controls and two patients show quantitative differences between the groups...
April 2018: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/29713446/evidence-of-oropharyngeal-dysfunction-in-feeding-in-the-rat-rotenone-model-of-parkinson-s-disease
#16
François D H Gould, Andrew Gross, Rebecca Z German, Jason R Richardson
Swallowing disorders in Parkinson's disease are not responsive to dopamine depletion therapy and contribute to morbidity. They are poorly understood owing to a lack of adequate models. We present the first evidence of oropharyngeal changes in a rotenone toxicity model of Parkinson's disease. Rats were recorded while feeding before and after daily rotenone injections at two different doses (2.75 mg/kg and 3 mg/kg). The higher dose had a much more severe parkinsonian phenotype than the low dose. Timing and amplitude of chewing changed, as did the coordination of chewing and swallowing...
2018: Parkinson's Disease
https://www.readbyqxmd.com/read/29712595/laparoscopic-heller-myotomy-versus-per-oral-endoscopic-myotomy-evidence-based-approach-to-the-treatment-of-esophageal-achalasia
#17
Francisco Schlottmann, Marco G Patti
Esophageal achalasia is a rare disorder characterized by a failure of the lower esophageal sphincter to relax during swallowing, combined with aperistalsis of the esophageal body. Treatment is not curative, but aims to eliminate the outflow resistance caused by the nonrelaxing lower esophageal sphincter. Current evidence suggests that both laparoscopic Heller myotomy and per oral endoscopic myotomy (POEM) are very effective in the relief of symptoms in patients with achalasia. Specifically, for type III achalasia, POEM may achieve higher success rates...
April 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/29712592/laparoscopic-heller-myotomy-for-achalasia-technical-aspects
#18
Francisco Schlottmann, Marco E Allaix, Marco G Patti
Esophageal achalasia is a primary esophageal motility disorder defined by the lack of esophageal peristalsis, and by a lower esophageal sphincter that fails to relax in response to swallowing. Patients' symptoms include dysphagia, regurgitation, aspiration, heartburn, and chest pain. Achalasia is a chronic condition without cure, and treatment options are aimed at providing symptomatic relief, improving esophageal emptying, and preventing the development of megaesophagus. Presently, a laparoscopic Heller myotomy with a partial fundoplication is considered the best treatment modality...
April 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/29712590/esophageal-achalasia-pathophysiology-clinical-presentation-and-diagnostic-evaluation
#19
Francisco Schlottmann, Rafael M L Neto, Fernando A M Herbella, Marco G Patti
Esophageal achalasia is a primary esophageal motility disorder characterized by the absence of esophageal peristalsis and failure of the lower esophageal sphincter to relax in response to swallowing. These abnormalities lead to impaired emptying of food from the esophagus into the stomach with resulting food stasis. Most patients experience severe dysphagia, and regurgitation can lead to aspiration and respiratory problems. Consequently, the quality of life of patients affected by achalasia is severely impacted...
April 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/29703430/relative-bioavailability-of-methylphenidate-extended-release-chewable-tablets-chewed-versus-swallowed-whole
#20
Richat Abbas, Ann C Childress, Praneeta Nagraj, Richard Rolke, Sally A Berry, Donna R Palumbo
PURPOSE: Methylphenidate hydrochloride extended-release chewable tablet (MPH ERCT) is approved for treatment of attention deficit hyperactivity disorder in patients aged 6 years and older. This article evaluates the pharmacokinetic parameters and relative bioavailability of MPH ERCT when chewed versus swallowed whole. METHODS: In this open-label, single-dose, 3-period, 3-treatment crossover study, 12 healthy adult volunteers were randomly assigned to treatment sequence...
April 24, 2018: Clinical Therapeutics
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