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https://www.readbyqxmd.com/read/29792222/longevity-and-pleural-mesothelioma-age-period-cohort-analysis-of-incidence-data-from-the-surveillance-epidemiology-and-end-results-seer-program-1973-2013
#1
Brent D Kerger
OBJECTIVE: This study investigates the hypothesis that an increasing fraction of incident pleural mesothelioma (PM) in the US population may be related to longevity, i.e., to expansion of the population over age 75 years with an age-related elevation in risk. An age-period-cohort analysis of the SEER 9 cancer registries (1973-2013) was conducted using 5-year intervals of age, calendar period, and birth cohort after stratification into four gender-age groups (male and female; 0-74 and 75+ years)...
May 23, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29792037/the-effect-of-iodopovidone-versus-bleomycin-in-chemical-pleurodesis
#2
Reza Bagheri, Marzieh Noori, Maryam Rajayi, Davood Attaran, Amir Mohammad Hashem Asna Ashari, Shahrzad Mohammadzadeh Lari, Reza Basiri, Fariba Rezaeetalab, Reza Afghani, Maryam Salehi
Background Malignant pleural effusion continues to be a common problem in patients with metastatic disease. This study was conducted to compare the efficacy and safety of bleomycin pleurodesis with povidone-iodine pleurodesis through a chest drain as palliative treatment for recurrent malignant pleural effusion. Methods Sixty cancer patients (36 males and 24 females) with recurrent malignant pleural effusion were enrolled in a prospective randomized trial. Thirty patients received povidone-iodine pleurodesis and 30 received bleomycin pleurodesis...
January 1, 2018: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/29791897/cutis-marmorata-telangiectatica-congenita-presenting-as-a-fetal-hemothorax
#3
Rodrigo A Mon, Ellen Mozurkewich, Marjorie C Treadwell, Deborah R Berman
We report a case of a fetus diagnosed at 28 weeks' gestation with a spontaneous prenatal hemothorax. Fetal intervention consisted of 2 thoracenteses with analysis of the pleural effusion. The pregnancy was further complicated by recurrence of the hemothorax, with subsequent mediastinal shift, hydrops, and nonreassuring antenatal testing requiring delivery at 31 weeks' gestation. Postnatal workup established the diagnoses of cutis marmorata telangiectatica congenita (CMTC) and pulmonary lymphangiectasia. The child is currently 4 years old and without any active medical issues or sequelae from the CMTC, pulmonary lymphangiectasia, or prenatal interventions...
May 23, 2018: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/29791072/massive-hemothorax-after-computed-tomography-guided-lung-tumor-biopsy-an-unusual-but-disastrous-complication
#4
Wei-Ming Huang, Hui-Chen Lin, Chia-Hung Chen, Chien-Wen Chen, Chih-Hsin Wang, Chung-Yao Huang, Ching-Che Wang, Chun-Chao Huang
Intercostal artery injury during transthoracic puncture is rare but is accompanied by high rates of morbidity and mortality. We report a case with metachronous double primary esophageal cancers and development of multiple lung nodules. Tissue proof for the lung nodules is required to guide the following treatment protocol. Our patient died soon after computed tomography-guided lung tumor biopsy was performed, as a result of procedure-related massive and uncontrolled hemothorax. The cause is likely intercostal artery injury related to the transthoracic puncture...
May 23, 2018: Thoracic Cancer
https://www.readbyqxmd.com/read/29790830/empyema-necessitans-in-a-six-month-old-girl
#5
P Goussard, Robert Gie, Jacques Janson, Savvas Andronikou
Empyema necessitans is a rare complication of acute bacterial pneumonia, especially in children. It is a complication of empyema characterised by the extension of pus from the pleural cavity into the thoracic wall to form a mass of purulent fluid in the adjacent soft tissue. An inflammatory chest wall mass following pneumonia caused by Streptococcus pneumonia in a six-month-old infant is reported. The case emphasises that children presenting with persistent fever and a painful chest wall mass following pneumonia should be investigated immediately as there might be an urgent need for surgery...
May 23, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/29790099/the-changes-underwent-by-free-fat-pads-used-for-pulmonary-air-leakage-repair
#6
Isao Matsumoto, Makoto Oda, Hiroko Ikeda, Keiichi Kimura, Masaya Tamura, Hirofumi Takemura
The use of free fat pads is effective for repairing pulmonary air leakage clinically. It has been reported that the free pericardial fat pad (FPFP) used to repair the lung remained at the transplanted site in many cases according to images. However, no information is available regarding what type of actual changes these free fat pads with no blood supply undergo. We examined changes in an FPFP that was used to repair pulmonary air leakage in a patient who underwent a surgery for lung cancer 1 year ago. Although the FPFP transplanted to the pleural defect remained without deforming morphologically in this patient 1 year after the first surgery, pathological findings suggested fat necrosis surrounded by fibrous tissue...
May 22, 2018: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29789808/the-value-of-18-f-fdg-pet-ct-mathematical-prediction-model-in-diagnosis-of-solitary-pulmonary-nodules
#7
Ling Wang, Yao Chen, Kun Tang, Jie Lin, Hong Zhang
Purpose: To establish an 18 F-fluorodeoxyglucose (18 F-FDG) positron emission tomography/computed tomography (PET/CT) mathematical prediction model to improve the diagnosis of solitary pulmonary nodules (SPNs). Materials and Methods: We retrospectively reviewed 177 consecutive patients who underwent 18 F-FDG PET/CT for evaluation of SPNs. The mathematical model was established by logistic regression analysis. The diagnostic capabilities of the model were calculated, and the areas under the receiver operating characteristic curve (AUC) were compared with Mayo and VA model...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29788037/mycoplasma-pneumoniae-among-children-hospitalized-with-community-acquired-pneumonia
#8
Preeta K Kutty, Seema Jain, Thomas H Taylor, Anna M Bramley, Maureen H Diaz, Krow Ampofo, Sandra R Arnold, Derek J Williams, Kathryn M Edwards, Jonathan A McCullers, Andrew T Pavia, Jonas M Winchell, Stephanie J Schrag, Lauri A Hicks
Background: The burden and epidemiology of Mycoplasma pneumoniae (Mp) among U.S. children (<18 years) hospitalized with community-acquired pneumonia (CAP) are poorly understood. Methods: In the Etiology of Pneumonia in the Community (EPIC) study, we prospectively enrolled 2254 children hospitalized with radiographically-confirmed pneumonia from January 2010-June 2012 and tested nasopharyngeal/oropharyngeal swabs for Mp using real-time polymerase chain reaction (PCR)...
May 17, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29786579/operative-treatment-of-corrosive-esophageal-strictures
#9
Volodymyr O Shaprynskyi, Yevhen V Shaprynskyi, Yaroslav V Karyi, Serhii A Lysenko, Oleg O Vorovskyi, Andrii I Semenenko
OBJECTIVE: Introduction: Nowadays operative treatment of corrosive esophageal strictures remains one of the difficult and unsolved problems in surgery. The level of postoperative complications such as anastomotic leak (develops in 7-30% of cases), infections, pneumonia, pleural empyema, mediastinitis, peritonitis, postoperative corrosive strictures is still rather high. The aim of our work was to improve the results of surgical treatment of patients with corrosive esophageal strictures by analyzing and refining on conservative therapy options as well as differentiated approach to each operative treatment method...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29785404/enhanced-suppressive-activity-of-regulatory-t-cells-in-the-microenvironment-of-malignant-pleural-effusions
#10
Joanna Budna, Mariusz Kaczmarek, Agata Kolecka-Bednarczyk, Łukasz Spychalski, Piotr Zawierucha, Joanna Goździk-Spychalska, Michał Nowicki, Halina Batura-Gabryel, Jan Sikora
Cancer metastatic spread to serous cavity causes malignant pleural effusions (MPEs), indicating dismal prognosis. Tumor microenvironment can implement suppressive activity on host immune responses. Thus, we investigated the prevalence of Tregs and the relationship between them and TGF- β and IL-10 concentrations and measured expression of FOXP3 , CTLA-4 , CD28 , and GITR genes, as well as protein expression of selected genes in benign effusions and MPEs. The percentage of Tregs was determined by means of multicolor flow cytometry system...
2018: Journal of Immunology Research
https://www.readbyqxmd.com/read/29785296/division-of-the-intersegmental-plane-using-electrocautery-for-segmentectomy-in-clinical-stage-i-non-small-cell-lung-cancer
#11
Mitsuyoshi Matsumoto, Koyo Shirahashi, Hirotaka Yamamoto, Yusaku Miyamaoto, Hiroyasu Komuro, Kiyoshi Doi, Hisashi Iwata
Background: Division of intersegmental planes is one of the important practical issues for segmentectomy to obtain feasible outcomes without relapse for clinical stage I non-small cell lung cancer. Almost all surgeons perform this procedure using a stapler. However, division of intersegmental planes for segmentectomy can also be performed by electrocautery. In this article, we demonstrate the merits and drawbacks of division of the intersegmental plane by electrocautery for segmentectomy...
April 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29785294/development-of-a-precision-multimodal-surgical-navigation-system-for-lung-robotic-segmentectomy
#12
Jean Marc Baste, Valentin Soldea, Samy Lachkar, Philippe Rinieri, Mathieu Sarsam, Benjamin Bottet, Christophe Peillon
Minimally invasive sublobar anatomical resection is becoming more and more popular to manage early lung lesions. Robotic-assisted thoracic surgery (RATS) is unique in comparison with other minimally invasive techniques. Indeed, RATS is able to better integrate multiple streams of information including advanced imaging techniques, in an immersive experience at the level of the robotic console. Our aim was to describe three-dimensional (3D) imaging throughout the surgical procedure from preoperative planning to intraoperative assistance and complementary investigations such as radial endobronchial ultrasound (R-EBUS) and virtual bronchoscopy for pleural dye marking...
April 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29785214/etiological-trends-and-patterns-of-antimicrobial-resistance-in-respiratory-infections
#13
Salma M Al-Zain Ahmed, Sara S Abdelrahman, Doua M Saad, Isra S Osman, Modasir G Osman, Eltahir A G Khalil
Background: Respiratory infections are one of the commonest causes of morbidity and mortality related to infectious diseases worldwide. The emergence of antimicrobial resistance is a major global health problem which is well established in developing countries. Good clinical suspicion and correct laboratory identification of respiratory infection causing organisms followed by the appropriate management are needed to compact both community-acquired and nosocomial infection respiratory infections...
2018: Open Microbiology Journal
https://www.readbyqxmd.com/read/29785165/thymic-carcinoma-a-rare-case-report
#14
Nidhi Bansal, Arnav Kr Roychoudhury, Harshi Dhingra
Introduction: Thymic carcinoma is a rare, invasive mediastinal neoplasm with a tendency to metastasize. They constitute a heterogeneous group of tumors that present differently in terms of both behavior and prognosis. Case report: We present a case of thymic carcinoma in a 55-year-old male patient known to suffer from Myasthenia gravis, whose chief complaints were fatigability, ptosis and coughing. All electromyography studies were done along with excision biopsy to reach the definitive diagnosis...
2018: Clujul Medical (1957)
https://www.readbyqxmd.com/read/29785020/glypican-1-immunohistochemistry-does-not-separate-mesothelioma-from-pulmonary-adenocarcinoma
#15
Kenrry Chiu, Lawrence Lee, Simon Cheung, Andrew M Churg
Immunohistochemistry (IHC) is used to help differentiate pleural mesothelioma from pulmonary adenocarcinoma in pleural biopsies and cytology specimens of pleural effusions due to overlapping morphologic features between these two malignancies. The aim of this study is to evaluate IHC glypican-1, a recently proposed marker for epithelioid mesothelioma, in our cohort of mesotheliomas and pulmonary adenocarcinoma. Tissue microarrays with duplicate cores from 33 cases of mesotheliomas (28 epithelioid type and five sarcomatoid type) and 21 cases of pulmonary adenocarcinoma were stained with glypican-1 antibody...
May 21, 2018: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/29783820/-efficacy-of-bronchoalveolar-lavage-and-its-influence-factors-in-the-treatment-of-mycoplasma-pneumoniae-pneumonia-with-atelectasis
#16
M Yang, D H Yang, X Yang, Y S Wang, L Wu, Z M Chen
Objective: To investigate the efficacy of bronchoalveolar lavage (BAL) and its influence factors in the treatment of Mycoplasma pneumoniae pneumonia (MPP) with atelectasis. Methods: A retrospective case control study was performed on hospitalized MPP patients with atelectasis and received BAL in the Department of Pulmonology, Children's Hospital Zhejiang University School of Medicine from January 1, 2015 to July 31, 2017. Fever relieved in 48 hours and chest imaging improved in one week after BAL were considered effective...
May 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29782063/intrapleural-streptokinase-was-effective-and-safe-for-children-with-multi-loculated-empyema-regardless-of-the-time-from-disease-onset
#17
Joseph L Mathew, Vimlesh Soni, Meenu Singh, Piyush Mittal, Sunit Singhi, Vikas Gautam, Kushaljit S Sodhi, Jayashree Muralidharan, Pankaj Vaidya
AIM: This study compared the efficacy of administering intrapleural streptokinase to children with multi-loculated empyema within 14 days or at any time after disease onset. METHODS: We studied children under 12 years who were admitted to a teaching hospital in Chandigarh, India, from July 2013 to June 2017 with multi-loculated empyema and received antibiotics, pleural drainage and intrapleural streptokinase. The first group only received three doses within 14 days of disease onset, the second received three doses any time after onset and the third group received 4-6 doses any time after onset...
May 21, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29781330/management-of-pleural-infections
#18
Lucía Ferreiro, José M Porcel, Silvia Bielsa, María Elena Toubes, José Manuel Álvarez-Dobaño, Luis Valdés
The management of infected pleural effusion is complex. Therapeutic resolution requires determining the following: appropriate antibiotic regimen, the need for pleural drainage, the optimal drainage tube size, and the need for intrapleural therapy or surgery. Areas covered: An updating of the latest advances in the management of parapneumonic pleural effusion based on the best evidence available is provided. Expert commentary: The correct management of parapneumonic pleural effusion is based on selecting an antibiotic regimen according to the origin of the pleural infection (community-acquired or nosocomial)...
May 20, 2018: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/29780625/is-a-5-mm-diameter-an-appropriate-cut-off-value-for-the-diagnosis-of-atypical-adenomatous-hyperplasia-and-adenocarcinoma-in-situ-on-chest-computed-tomography-and-pathological-examination
#19
Xiaohuan Pan, Xinguan Yang, Jingxu Li, Xiao Dong, Jianxing He, Yubao Guan
Background: Preinvasive lesions, such as atypical adenomatous hyperplasia (AAH) and adenocarcinoma in situ (AIS), usually appear as pure ground-glass nodules (pGGNs) on thin-section computed tomography (TSCT). AAH is usually less than 5 mm wide on imaging and pathological examinations. We aimed to determine whether a 5-mm cut-off value was appropriate for the diagnosis of AAH and AIS. Methods: We retrospectively analyzed the performance of TSCT in evaluating 80 pathologically confirmed preinvasive lesions (33 AAH lesions in 31 patients and 47 AIS lesions in 45 patients)...
April 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29780196/light-fluence-dosimetry-in-lung-simulating-cavities
#20
Timothy C Zhu, Michele M Kim, Jonah Padawer, Andreea Dimofte, Mary Potasek, Karl Beeson, Evgueni Parilov
Accurate light dosimery is critical to ensure consistent outcome for pleural photodynamic therapy (pPDT). Ellipsoid shaped cavities with different sizes surrounded by turbid medium are used to simulate the intracavity lung geometry. An isotropic light source is introduced and surrounded by turbid media. Direct measurements of light fluence rate were compared to Monte Carlo simulated values on the surface of the cavities for various optical properties. The primary component of the light was determined by measurements performed in air in the same geometry...
January 2018: Proceedings of SPIE
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