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https://www.readbyqxmd.com/read/28723828/social-disparities-in-early-intervention-service-use-and-provider-reported-outcomes
#1
Mary A Khetani, Zachary Richardson, Beth M McManus
OBJECTIVE: To describe social disparities in early intervention (EI) service use and provider-reported outcomes. METHODS: Secondary data analysis of administrative data to ascertain EI service use of all EI and discipline-specific services and child and family characteristics. Adjusted logistic regression models estimated the odds of receiving each type of core EI service. Adjusted median regression models estimated differences in EI intensity for each type of core EI service...
July 17, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28723631/cbl-b-predicts-postoperative-survival-in-patients-with-resectable-pancreatic-ductal-adenocarcinoma
#2
Qian Dong, Yuteng Ma, Yao Zhang, Xiujuan Qu, Zhi Li, Yafei Qi, Yunpeng Liu, Ce Li, Kai Li, Xianghong Yang, Xiaofang Che
Casitas B-lineage lymphoma b (Cbl-b) is a ubiquitin-protein ligase and a signal transducing adaptor protein involved in immune regulation, and it may be involved in the development and progression of cancer. We investigated the association between Cbl-b expression and prognosis in patients with resectable pancreatic ductal adenocarcinoma (PDAC). The clinicopathological characteristics and survival data of 134 patients with surgery for PDAC between January 2009 and February 2012 were retrospectively evaluated, and Cbl-b expression was assayed by immunohistochemical staining...
June 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/28723117/versatile-barometer-biosensor-based-on-au-pt-core-shell-nanoparticle-probe
#3
Qiangqiang Fu, Ze Wu, Dan Du, Chengzhou Zhu, Yuehe Lin, Yong Tang
There is a high global demand for sensitive, portable, user-friendly, and cost-effective biosensors. In this work, we introduce a barometer-based biosensor for the detection of a broad range of targets. The device is operated by measuring the pressure change produced by oxygen (O2) generation in a limited chamber using a portable barometer. The design employs core-shell Au@Pt nanoparticles (Au@PtNPs) as the bioassay probe to catalyze the decomposition of H2O2 and the release of O2. As a proof of concept, we developed barometer-based immunosensors to detect carcinoembryonic antigen (CEA) and ractopamine (Rac)...
June 23, 2017: ACS Sensors
https://www.readbyqxmd.com/read/28723093/plasmonic-aerogels-as-a-3d-nanoscale-platform-for-solar-fuels-photocatalysis
#4
Paul A DeSario, Jeremy J Pietron, Adam Dunkelberger, Todd H Brintlinger, Olga Baturina, Rhonda M Stroud, Jeffrey C Owrutsky, Debra R Rolison
We use plasmonic Au-TiO2 aerogels as a platform in which to marry synthetically thickened particle-particle junctions in TiO2 aerogel networks and Au||TiO2 interfaces and then investigate their cooperative influence on photocatalytic hydrogen (H2) generation under both broadband (i.e., UV + visible light) and visible-only excitation. In doing so, we elucidate the dual functions that incorporated Au can play as a water reduction/H2 generation co-catalyst and as a plasmonic sensitizer. We also introduce non-plasmonic Pt co-catalyst nanoparticles into our composite aerogels in order to leverage the catalytic water-reducing abilities of Pt...
July 19, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28722733/a-polyacrylonitrile-copolymer-silica-template-for-three-dimensional-hierarchical-porous-carbon-as-a-pt-catalyst-support-for-the-oxygen-reduction-reaction
#5
Minmin Liu, Jian Li, Chao Cai, Ziwei Zhou, Yun Ling, Rui Liu
Herein, we report a novel route to construct a hierarchical three-dimensional porous carbon (3DC) through a copolymer-silica assembly. In the synthesis, silica acts as a hard template and leads to the formation of an interconnected 3D macropore, whereas styrene-co-acrylonitrile polymer has been used as both a carbon source and a soft template for micro- and meso-pores. The obtained 3DC materials possess a large surface area (∼550.5 m(2) g(-1)), which facilitates high dispersion of Pt nanoparticles on the carbon support...
July 19, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28722151/the-antithrombotic-and-haemostatic-effects-of-lassbio-752-a-synthetic-orally-active-compound-in-an-arterial-and-venous-thrombosis-model-in-rats
#6
Flávia S Frattani, Lidia M Lima, Eliezer J Barreiro, Russolina B Zingali
OBJECTIVES: In this work, we further investigated the effect of the compound LASSBio-752 in thrombosis models in rats. METHODS: Arterial and venous thrombosis model, ex-vivo recalcification time and aPTT and PT. KEY FINDINGS: In the venous thrombosis model, oral administration of LASSBio-752 [48.2 mg (100 μmol)/kg] one hour before the thrombus induction decreased thrombus weight by 37 ± 0.2%. Interestingly, the antithrombotic action of this compound [48...
July 19, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/28722046/temperature-and-composition-dependent-phase-transitions-of-lead-free-piezoelectric-bi0-5na0-5-tio3-batio3-thin-films
#7
Zhen Zhou, Jin Luo, Wei Sun, Jing-Feng Li
Extensive studies on (Bi0.5Na0.5)TiO3-BaTiO3 piezoceramics have aroused growing interest in developing high-performance piezoelectric films based on this promising lead-free piezoelectric system. High quality (1 - x%) (Bi0.5Na0.5)TiO3-x% BaTiO3 (x = 0-15) thin films were synthesized on Pt(111)/Ti/SiO2/Si(100) substrates via a sol-gel method. The phase transitions as functions of composition and temperature were investigated by X-ray diffraction (XRD) and temperature-dependent Raman spectra analysis. A morphotropic phase boundary (MPB) located at 5 ≤ x ≤ 10 was found in the films, being identical to that in bulk materials...
July 19, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28721117/experiential-learning-in-physical-therapy-education
#8
Susan N Smith, Amy F Crocker
BACKGROUND AND PURPOSE: Experiential learning can provide students in entry-level physical therapy (PT) education programs the opportunity to practice skills and techniques, learned in the classroom, in a real-world setting. Experiential learning is currently being utilized in all entry-level PT programs in the form of professional practice experiences but may be integrated throughout the curriculum to enhance student engagement and knowledge application and retention. The purpose of this paper is to express the need for increased integration of experiential learning into entry-level PT education curricula...
2017: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/28720804/the-lower-pt-limit-of-deep-hydrocarbon-synthesis-by-caco3-aqueous-reduction
#9
E Mukhina, A Kolesnikov, V Kutcherov
The deep abiogenic synthesis of hydrocarbons is possible under the conditions of the asthenosphere. We have found that this process can also occur under the mineral and thermobaric conditions of subducting slabs. We have investigated the abiogenic synthesis of hydrocarbon systems at pressures of 2.0-6.6 GPa and temperatures of 250-600 °C. The determined lower thermobaric limit of the reaction at 280-300 °C and 2-3 GPa corresponds to a depth of 70-80 km during cold subduction. The hydrocarbon fluid formed in the slab can migrate upwards through the network of faults and fractures to form petroleum deposits...
July 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28720662/proximal-tubule-apical-endocytosis-is-modulated-by-fluid-shear-stress-via-an-mtor-dependent-pathway
#10
Kimberly R Long, Katherine E Shipman, Youssef Rbaibi, Elizabeth V Menshikova, Vladimir B Ritov, Megan L Eshbach, Yu Jiang, Edwin K Jackson, Catherine J Baty, Ora A Weisz
Cells lining the proximal tubule (PT) have unique membrane specializations that are required to maintain the high capacity ion transport and endocytic functions of this nephron segment. PT cells in vivo acutely regulate ion transport in response to changes in glomerular filtration rate (GFR) to maintain glomerulotubular balance. PT cells in culture upregulate endocytic capacity in response to acute changes in fluid shear stress (FSS); however it is not known whether GFR modulates PT endocytosis to enable maximally efficient uptake of filtered proteins in vivo Here we show that cells cultured under continuous FSS develop an expanded apical endocytic pathway as well as increased endocytic capacity and lysosomal biogenesis...
July 18, 2017: Molecular Biology of the Cell
https://www.readbyqxmd.com/read/28719996/efficacy-of-short-term-robot-assisted-rehabilitation-in-patients-with-hand-paralysis-after-stroke-a-randomized-clinical-trial
#11
Jorge H Villafañe, Giovanni Taveggia, Silvia Galeri, Luciano Bissolotti, Chiara Mullè, Grace Imperio, Kristin Valdes, Alberto Borboni, Stefano Negrini
BACKGROUND: We evaluated the effectiveness of robot-assisted motion and activity in additional to physiotherapy (PT) and occupational therapy (OT) on stroke patients with hand paralysis. METHODS: A randomized controlled trial was conducted. Thirty-two patients, 34.4% female (mean ± SD age: 68.9 ± 11.6 years), with hand paralysis after stroke participated. The experimental group received 30 minutes of passive mobilization of the hand through the robotic device Gloreha (Brescia, Italy), and the control group received an additional 30 minutes of PT and OT for 3 consecutive weeks (3 d/wk) in addition to traditional rehabilitation...
February 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28719500/a-randomized-controlled-study-of-a-fully-liquid-dtap-ipv-hb-prp-t-hexavalent-vaccine-for-primary-and-booster-vaccinations-of-healthy-infants-and-toddlers-in-latin-america
#12
Pío López, Adriano Arguedas Mohs, Arturo Abdelnour Vásquez, Maria Consuelo-Miranda, Emmanuel Feroldi, Fernando Noriega, Emilia Jordanov, Siham B'Chir, Betzana Zambrano
BACKGROUND: Hexavalent diphtheria (D)-tetanus (T)-acellular pertussis (aP)-inactivated poliovirus (IPV)-hepatitis B (HB)-Haemophilus influenzae type b (PRP-T)-containing vaccines are increasingly the standard of care. This study evaluated the primary series (NCT01177722) and booster (NCT01444781) of a fully liquid DTaP-IPV-HB-PRP-T vaccine in Latin America. METHODS: Infants (N=1375) received HB vaccine at birth and were randomized to one of three batches of the investigational DTaP-IPV-HB-PRP-T or licensed control vaccine (DTaP-HB-IPV//PRP-T) at 2-4-6 months of age, co-administered with 7-valent pneumococcal conjugate vaccine (PCV7) (2-4-6 months) and rotavirus vaccine (2-4 months)...
July 14, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28719034/ultrathin-vein-like-iridium-tin-nanowires-with-abundant-oxidized-tin-as-high-performance-ethanol-oxidation-electrocatalysts
#13
Meiwu Zhu, Qi Shao, Yecan Pi, Jun Guo, Bin Huang, Yong Qian, Xiaoqing Huang
Iridium (Ir) holds great promise for ethanol oxidation reaction (EOR), while its practical applications suffer from the limited shape-controlled synthesis due to its low-energy barrier for nucleation. To overcome this limitation, the preparation of a new class of ultrathin vein-like Ir-tin nanowires (IrSn NWs) with abundant oxidized Sn is reported. By tuning the ratio of Ir to Sn, the optimized Ir67 Sn33 /C exhibits the highest mass density of 95.6 mA mg(-1) Ir for EOR at low potential (0.04 V), which is 4...
July 18, 2017: Small
https://www.readbyqxmd.com/read/28719031/desert-beetle-inspired-superwettable-patterned-surfaces-for-water-harvesting
#14
Zhenwei Yu, Frank F Yun, Yanqin Wang, Li Yao, Shixue Dou, Kesong Liu, Lei Jiang, Xiaolin Wang
With the impacts of climate change and impending crisis of clean drinking water, designing functional materials for water harvesting from fog with large water capacity has received much attention in recent years. Nature has evolved different strategies for surviving dry, arid, and xeric conditions. Nature is a school for human beings. In this contribution, inspired by the Stenocara beetle, superhydrophilic/superhydrophobic patterned surfaces are fabricated on the silica poly(dimethylsiloxane) (PDMS)-coated superhydrophobic surfaces using a pulsed laser deposition approach with masks...
July 18, 2017: Small
https://www.readbyqxmd.com/read/28719030/polygenic-risk-for-schizophrenia-and-neurocognitive-performance-in-patients-with-schizophrenia
#15
Shi-Heng Wang, Po-Chang Hsiao, Ling-Ling Yeh, Chih-Min Liu, Chen-Chung Liu, Tzung-Jeng Hwang, Ming H Hsieh, Yi-Ling Chien, Yi-Ting Lin, Sharon D Chandler, Stephen V Faraone, Nan Laird, Benjamin Neale, Steve A McCarroll, Stephen J Glatt, Ming T Tsuang, Hai-Gwo Hwu, Wei J Chen
Both neurocognitive deficits and schizophrenia are highly heritable. Genetic overlap between neurocognitive deficits and schizophrenia has been observed in both the general population and in clinical samples. This study aimed to examine if the polygenic architecture of susceptibility to schizophrenia modified neurocognitive performance in schizophrenia patients. Schizophrenia polygenic risk scores (PRS) were first derived from the Psychiatric Genomics Consortium (PGC) on schizophrenia, and then the scores were calculated in our independent sample of 1130 schizophrenia trios, who had PsychChip data and were part of the Schizophrenia Families from Taiwan project...
July 18, 2017: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/28718911/clear-cell-renal-cell-carcinoma-validation-of-who-isup-grading
#16
Julien Dagher, Brett Delahunt, Nathalie Rioux-Leclercq, Lars Egevad, John R Srigley, Geoffrey Coughlin, Nigel Dunglinson, Troy Gianduzzo, Boon Kua, Greg Malone, Ben Martin, John Preston, Morgan Pokorny, Simon Wood, John Yaxley, Hemamali Samaratunga
AIM: In 2012, the International Society of Urological Pathology (ISUP) introduced a novel grading system for clear cell and papillary renal cell carcinoma (RCC) based upon increasing nucleolar prominence in grades 1 to 3, with the presence of extreme nuclear pleomorphism and/or tumour giant cells and/or sarcomatoid and/or rhabdoid differentiation as criteria for grade 4. This system is now incorporated in the latest World Health Organization renal tumour classification, being designated WHO/ISUP grading...
July 18, 2017: Histopathology
https://www.readbyqxmd.com/read/28718471/two-dimensional-metal-organic-frameworks-with-high-thermoelectric-efficiency-through-metal-ion-selection
#17
Yuping He, Catalin D Spataru, Francois Léonard, Reese E Jones, Michael E Foster, Mark D Allendorf, A Alec Talin
Two-dimensional (2D) materials have attracted much attention due to their novel properties. An exciting new class of 2D materials based on metal-organic frameworks (MOFs) has recently emerged, displaying high electrical conductivity, a rarity among organic nanoporous materials. The emergence of these materials raises intriguing questions about their fundamental electronic, optical, and thermal properties, but few studies exist in this regard. Here we present an atomistic study of the thermoelectric properties of crystalline 2D MOFs X3(HITP)2 with X = Ni, Pd or Pt, and HITP = 2,3,6,7,10,11-hexaiminotriphenylene, using both ab initio transport models and classical molecular dynamics simulations...
July 18, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28718296/real-life-management-of-venous-thromboembolism-with-rivaroxaban-results-from-experience-vte-an-italian-epidemiological-survey
#18
Davide Imberti, Giovanni Barillari
Two large randomized controlled trials examined the efficacy and safety of rivaroxaban for the treatment of venous thromboembolism (VTE). The aim of this epidemiological study was to analyze a cohort of Italian patients affected by VTE who were treated with rivaroxaban in clinical practice. The data were collected by physicians using an online electronic questionnaire. The study was performed during a 6-month period from January to June 2014. We analyzed the clinical characteristics, risk factors for VTE, comorbidities, diagnostic techniques, and treatments in the whole population and in the subgroups with deep vein thrombosis (DVT) only, pulmonary embolism (PE) only, and DVT+PE...
January 1, 2017: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/28718280/contact-effect-of-res2-metal-interface
#19
Jae Young Park, Hang-Eun Joe, Hyong Seo Yoon, SangHyuk Yoo, Taekyeong Kim, Keonwook Kang, Byung-Kwon Min, Seong Chan Jun
Rhenium disulfide (ReS2) has attracted immense interest as a promising two-dimensional material for optoelectronic devices owing to its outstanding photonic response based on its energy band gap's insensitivity to the layer thickness. Here, we theoretically calculated the electrical band structure of mono-, bi-, and tri-layer ReS2 and experimentally found the work function to be 4.8 eV, which was shown to be independent of the layer thickness. We also evaluated the contact resistance of a ReS2 field-effect transistor (FET) using a Y-function method with various metal electrodes, including graphene...
July 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28717985/basic-echocardiography-for-undergraduate-students-a-comparison-of-different-peer-teaching-approaches
#20
G Gradl-Dietsch, A K Menon, A Gürsel, A Götzenich, N Hatam, A Aljalloud, S Schrading, F Hölzl, M Knobe
BACKGROUND: The aim of this study was to assess the impact of different teaching interventions in a peer-teaching environment on basic echocardiography skills and to examine the influence of gender on learning outcomes. METHODS: We randomly assigned 79 s year medical students (55 women, 24 men) to one of four groups: peer teaching (PT), peer teaching using Peyton's four-step approach (PPT), team based learning (TBL) and video-based learning (VBL). All groups received theoretical and practical hands-on training according to the different approaches...
July 17, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
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