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https://www.readbyqxmd.com/read/28092935/alloying-strategy-in-cu-in-ga-se-quantum-dots-for-high-efficiency-quantum-dot-sensitized-solar-cells
#1
Wenxiang Peng, Jun Du, Zhenxiao Pan, Naoki Nakazawa, Jiankun Sun, Zhonglin Du, Gencai Shen, Juan Yu, Jin-Song Hu, Qing Shen, Xinhua Zhong
I-III-VI2 group "green" quantum dots (QDs) are attracting increasing attentions in photoelectronic conversion applications. Herein, based on the "simultaneous nucleation and growth" approach, Cu-In-Ga-Se (CIGSe) QDs with light harvesting range about 1000 nm were synthetized and used as sensitizer to construct quantum dot sensitized solar cells (QDSCs). Inductively coupled plasma-atomic emission spectrometry (ICP-AES), wild-angle X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS) analyses demonstrate that the Ga element was alloyed in the Cu-In-Se (CISe) host...
January 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28092076/determination-of-trace-elements-in-cow-placenta-by-tungsten-coil-atomic-emission-spectrometry
#2
Daniel A Gonçalves, Ana C Soncin, George L Donati, Mirian C Dos Santos
Tungsten coil atomic emission spectrometry (WCAES) is used to determine trace levels of Mn (403.1 nm) and Cr (425.5 nm) in cow placenta. All samples were collected in Ilha Solteira, SP, Brazil. The instrumental setup is based on a tungsten filament extracted from 150 W, 15 V microscope light bulbs, a solid state power supply, fused silica lens, crossed Czerny-Turner spectrograph, and a thermoelectrically cooled charge-coupled device detector. The limits of detection (LOD) and quantification (LOQ) for Cr are 2 and 8 μg L(-1), and 20 and 60 μg L(-1) for Mn, respectively...
January 16, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28087006/new-insights-into-the-pathogenesis-and-treatment-of-heavy-chain-deposition-disease
#3
Jonathan J Hogan, Glen S Markowitz
Heavy chain deposition disease is defined by the presence of tissue deposits of truncated monoclonal Ig heavy chains, usually associated with an underlying plasma cell clone. In this issue of Kidney International, Bridoux et al. described the clinical, histologic, and molecular characterization of 15 patients with heavy chain deposition disease, which is the largest case series to date. Notable findings included the frequent presence of C3 deposits and hypocomplementemia, the uniform finding of truncated heavy chains with the deletion in the heavy chain constant region 1, and the common occurrence of an abnormal serum-free κ:λ ratio, despite the absence of light-chain tissue deposition...
February 2017: Kidney International
https://www.readbyqxmd.com/read/28076415/structure-and-recognition-of-a-novel-hiv-1-gp120-gp41-interface-antibody-that-caused-mper-exposure-through-viral-escape
#4
Constantinos Kurt Wibmer, Jason Gorman, Gabriel Ozorowski, Jinal N Bhiman, Daniel J Sheward, Debra H Elliott, Julie Rouelle, Ashley Smira, M Gordon Joyce, Nonkululeko Ndabambi, Aliaksandr Druz, Mangai Asokan, Dennis R Burton, Mark Connors, Salim S Abdool Karim, John R Mascola, James E Robinson, Andrew B Ward, Carolyn Williamson, Peter D Kwong, Lynn Morris, Penny L Moore
A comprehensive understanding of the regions on HIV-1 envelope trimers targeted by broadly neutralizing antibodies may contribute to rational design of an HIV-1 vaccine. We previously identified a participant in the CAPRISA cohort, CAP248, who developed trimer-specific antibodies capable of neutralizing 60% of heterologous viruses at three years post-infection. Here, we report the isolation by B cell culture of monoclonal antibody CAP248-2B, which targets a novel membrane proximal epitope including elements of gp120 and gp41...
January 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28075553/double-layer-graphene-outperforming-monolayer-as-catalyst-on-silicon-photocathode-for-hydrogen-production
#5
Uk Sim, Joonhee Moon, Joohee Lee, JungHyun An, Hyo-Yong Ahn, Dong Jin Kim, Insu Jo, Cheolho Jeon, Seungwu Han, Byung Hee Hong, Ki Tae Nam
Photoelectrochemical cells are used to split hydrogen and oxygen from water molecules to generate chemical fuels to satisfy our ever-increasing energy demands. However, it is a major challenge to design efficient catalysts to use in the photoelectochemical process. Recently, research has focused on carbon-based catalysts, as they are non-precious and environmentally benign. Interesting advances have also been made in controlling nanostructure interfaces and in introducing new materials as catalysts in the photoelectrochemical cell...
January 11, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28074961/tunable-electrical-properties-of-multilayer-hfse2-field-effect-transistors-by-oxygen-plasma-treatment
#6
Moonshik Kang, Servin Rathi, Inyeal Lee, Lijun Li, Muhammad Atif Khan, Dongsuk Lim, Yoontae Lee, Jinwoo Park, Sun Jin Yun, Doo-Hyeb Youn, Chungsam Jun, Gil-Ho Kim
HfSe2 field effect transistors are systematically studied in order to selectively tune their electrical properties by optimizing layer thickness and oxygen plasma treatment. The optimized plasma-treated HfSe2 field effect transistors showed a high on/off ratio improvement of four orders of magnitude, from 27 to 10(5), a field effect mobility increase from 2.16 to 3.04 cm(2) V(-1) s(-1), a subthreshold swing improvement from 30.6 to 4.8 V dec(-1), and a positive threshold voltage shift between depletion mode and enhancement mode, from -7...
January 11, 2017: Nanoscale
https://www.readbyqxmd.com/read/28074918/regulation-of-plasma-histamine-levels-by-the-mast-cell-clock-and-its-modulation-by-stress
#7
Yuki Nakamura, Kayoko Ishimaru, Shigenobu Shibata, Atsuhito Nakao
At steady state, plasma histamine levels exhibit circadian variations with nocturnal peaks, which is implicated in the nighttime exacerbation of allergic symptoms. However, the regulatory mechanisms are largely unexplored. This study determined how steady-state plasma histamine levels are regulated and affected by environmental factors. We found that plasma histamine levels decreased in mast cell-deficient mice and their circadian variations were lost in mast cell-deficient mice reconstituted with bone marrow-derived mast cells (BMMCs) harboring a mutation in the circadian gene Clock...
January 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28071681/increased-impedance-near-cut-off-in-plasma-like-media-leading-to-emission-of-high-power-narrow-bandwidth-radiation
#8
M S Hur, B Ersfeld, A Noble, H Suk, D A Jaroszynski
Ultra-intense, narrow-bandwidth, electromagnetic pulses have become important tools for exploring the characteristics of matter. Modern tuneable high-power light sources, such as free-electron lasers and vacuum tubes, rely on bunching of relativistic or near-relativistic electrons in vacuum. Here we present a fundamentally different method for producing narrow-bandwidth radiation from a broad spectral bandwidth current source, which takes advantage of the inflated radiation impedance close to cut-off in a medium with a plasma-like permittivity...
January 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28068904/long-term-kinetics-of-zika-virus-rna-and-antibodies-in-body-fluids-of-a-vasectomized-traveller-returning-from-martinique-a-case-report
#9
Guenter Froeschl, Kristina Huber, Frank von Sonnenburg, Hans-Dieter Nothdurft, Gisela Bretzel, Michael Hoelscher, Lothar Zoeller, Matthias Trottmann, Francisco Pan-Montojo, Gerhard Dobler, Silke Woelfel
BACKGROUND: The magnitude of the current Zika virus (ZIKV) epidemic has led to a declaration of a Public Health Emergency of International Concern by the WHO. Findings of viable viral particles in semen for several weeks are corroborating reports of sexual transmission of ZIKV. Serious consequences of a positive diagnostic result particularly in the pregnant patient are calling for precise diagnostic tools also at later time points after infection. Currently, recommendations suggest a diagnostic period of direct viral detection of 5 to 7 days after onset of symptoms in serum or plasma, and up to 3 weeks in urine samples...
January 10, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28068607/micro-electromechanical-film-bulk-acoustic-sensor-for-plasma-and-whole-blood-coagulation-monitoring
#10
Da Chen, Shuren Song, Jilong Ma, Zhen Zhang, Peng Wang, Weihui Liu, Qiuquan Guo
Monitoring blood coagulation is an important issue in the surgeries and the treatment of cardiovascular diseases. In this work, we reported a novel strategy for the blood coagulation monitoring based on a micro-electromechanical film bulk acoustic resonator. The resonator was excited by a lateral electric field and operated under the shear mode with a frequency of 1.9GHz. According to the apparent step-ladder curves of the frequency response to the change of blood viscoelasticity, the coagulation time (prothrombin time) and the coagulation kinetics were measured with the sample consumption of only 1μl...
December 30, 2016: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28067508/coherent-brightfield-microscopy-provides-the-spatiotemporal-resolution-to-study-early-stage-viral-infection-in-live-cells
#11
Yi-Fan Huang, Guan-Yu Zhuo, Chun-Yu Chou, Cheng-Hao Lin, Wen Chang, Chia-Lung Hsieh
Viral infection starts with a virus particle landing on a cell surface followed by penetration of the plasma membrane. Due to the difficulty of measuring the rapid motion of small-sized virus particles on the membrane, little is known about how a virus particle reaches an endocytic site after landing at a random location. Here, we use coherent brightfield (COBRI) microscopy to investigate early stage viral infection with ultrahigh spatiotemporal resolution. By detecting intrinsic scattered light via imaging-based interferometry, COBRI microscopy allows us to track the motion of a single vaccinia virus particle with nanometer spatial precision (<3 nm) in 3D and microsecond temporal resolution (up to 100,000 frames per second)...
January 13, 2017: ACS Nano
https://www.readbyqxmd.com/read/28066942/antioxidant-status-and-expression-of-inflammatory-genes-in-gut-and-liver-of-piglets-fed-different-dietary-methionine-concentrations
#12
J O Zeitz, S Kaltenböck, E Most, K Eder
This study investigated the hypothesis that dietary concentrations of methionine (Met), as a precursor of cysteine which is a constituent of glutathione (GSH), affect tissue antioxidant concentrations and the antioxidant defence system in pigs. Forty-five piglets (DanZucht × Pietrain) were allotted to three groups of similar mean body weight (11.0 ± 0.9 kg). The basal diet was composed of barley, wheat, corn starch, soybean oil, sucrose, cellulose and a mineral supplement with suboptimal concentrations of Met and was supplemented with dl-Met to reach 0...
January 8, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28066146/high-fat-diet-confers-vascular-hyper-contractility-against-angiotensin-ii-through-upregulation-of-mlck-and-cpi-17
#13
Jee In Kim
Obesity is a critical risk factor for the hypertension. Although angiotensin II (Ang II) in obese individuals is known to be upregulated in obesity-induced hypertension, direct evidence that explains the underlying mechanism for increased vascular tone and consequent increase in blood pressure (BP) is largely unknown. The purpose of this study is to investigate the novel mechanism underlying Ang II-induced hyper-contractility and hypertension in obese rats. Eight-week old male Sprague-Dawley rats were fed with 60% fat diet or normal diet for 4 months...
January 2017: Korean Journal of Physiology & Pharmacology
https://www.readbyqxmd.com/read/28066135/ameliorative-effects-of-atractylodin-on-intestinal-inflammation-and-co-occurring-dysmotility-in-both-constipation-and-diarrhea-prominent-rats
#14
Changchun Yu, Yongjian Xiong, Dapeng Chen, Yanli Li, Bin Xu, Yuan Lin, Zeyao Tang, Chunling Jiang, Li Wang
Intestinal disorders often co-occur with inflammation and dysmotility. However, drugs which simultaneously improve intestinal inflammation and co-occurring dysmotility are rarely reported. Atractylodin, a widely used herbal medicine, is used to treat digestive disorders. The present study was designed to characterize the effects of atractylodin on amelioration of both jejunal inflammation and the co-occurring dysmotility in both constipation-prominent (CP) and diarrhea-prominent (DP) rats. The results indicated that atractylodin reduced proinflammatory cytokines TNF-α, IL-1β, and IL-6 in the plasma and inhibited the expression of inflammatory mediators iNOS and NF-kappa B in jejunal segments in both CP and DP rats...
January 2017: Korean Journal of Physiology & Pharmacology
https://www.readbyqxmd.com/read/28065308/studying-cytokinesis-and-midbody-remnants-using-correlative-light-scanning-em
#15
S Frémont, A Echard
Cytokinesis is an essential step of cell proliferation leading to the physical separation of the dividing cells. Cytokinesis relies on both large scale and local scale cell shape changes, and terminates with the final abscission cut that requires close apposition of the plasma membrane. While furrow ingression is a prominent feature of the early phase of cytokinesis and is easy to visualize in all models, from dividing eggs to culture cells, the later steps of cytokinesis until abscission can be much more difficult to visualize...
2017: Methods in Cell Biology
https://www.readbyqxmd.com/read/28063031/pharmacokinetics-and-pharmacodynamics-of-afamelanotide-and-its-clinical-use-in-treating-dermatologic-disorders
#16
REVIEW
Elisabeth I Minder, Jasmin Barman-Aksoezen, Xiaoye Schneider-Yin
Afamelanotide, the first α-melanocyte-stimulating hormone (MSH) analogue, synthesized in 1980, was broadly investigated in all aspects of pigmentation because its activity and stability were higher than the natural hormone. Afamelanotide binds to the melanocortin-1 receptor (MC1R), and MC1R signaling increases melanin synthesis, induces antioxidant activities, enhances DNA repair processes and modulates inflammation. The loss-of-function variants of the MC1R present in fair-skinned Caucasians are less effectively activated by the natural hormone...
January 6, 2017: Clinical Pharmacokinetics
https://www.readbyqxmd.com/read/28061989/high-risk-smoldering-myeloma-perspective-on-watchful-monitoring
#17
REVIEW
Siyang Leng, Suzanne Lentzsch
In a 2008 paper, Dispenzieri and colleagues at the Mayo Clinic proposed a risk stratification system for patients with smoldering multiple myeloma (SMM) based on the presence of three risk factors: serum M-protein ≥3 g/dL, bone marrow plasma cell percentage ≥10%, and a free light chain (FLC) ratio (κ to λ) of either ≤0.125 or ≥8. The patient in this vignette has all three risk factors, classifying him as high-risk, with an associated median time to progression (TTP) of 1.9 years. This is significantly worse than a patient with intermediate-risk (median TTP 5...
December 2016: Seminars in Oncology
https://www.readbyqxmd.com/read/28060224/granulocytic-myeloid-derived-suppressor-cells-increased-in-early-phases-of-primary-hiv-infection-depending-on-trail-plasma-level
#18
N Tumino, M T Bilotta, C Pinnetti, A Ammassari, A Antinori, F Turchi, C Agrati, R Casetti, V Bordoni, E Cimini, I Abbate, M R Capobianchi, F Martini, A Sacchi
BACKGROUND: It has been demonstrated that Myeloid Derived Suppressor Cells (MDSC) are expanded in HIV-1 infected individuals and correlated with disease progression. The phase of HIV infection during which MDSC expansion occurs, and the mechanisms that regulate this expansion remain to be established. In this study we evaluated the frequency of MDSC in patients during primary HIV infection, and factors involved in MDSC control. METHODS: Patients with primary (PHI) and chronic (CHI) HIV infection were enrolled...
January 2, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28060076/epibulbar-plasmacytoma-masquerading-as-subconjunctival-hemorrhage-in-a-patient-with-multiple-myeloma
#19
Amanda Bradley, Amy Estes, Lane Ulrich, Dilip Thomas, David Gay
PURPOSE: We report a 75-year-old woman with a history of multiple myeloma immunoglobulin D (IgD) variant, who presented with an epibulbar plasmacytoma masquerading as a subconjunctival hemorrhage. METHODS: Magnetic resonance imaging of the brain and orbits with and without contrast was obtained and surgical biopsy of the subconjunctival lesion was performed; histopathology confirmed the diagnosis of plasmacytoma. RESULTS: Subconjunctival biopsy revealed a plasma cell neoplasm infiltrate in the episcleral layer...
February 2017: Cornea
https://www.readbyqxmd.com/read/28059160/low-temperature-remote-plasma-enhanced-atomic-layer-deposition-of-zro2-zircone-nanolaminate-film-for-efficient-encapsulation-of-flexible-organic-light-emitting-diodes
#20
Zheng Chen, Haoran Wang, Xiao Wang, Ping Chen, Yunfei Liu, Hongyu Zhao, Yi Zhao, Yu Duan
Encapsulation is essential to protect the air-sensitive components of organic light-emitting diodes (OLEDs) such as active layers and cathode electrodes. In this study, hybrid zirconium inorganic/organic nanolaminates were fabricated using remote plasma enhanced atomic layer deposition (PEALD) and molecular layer deposition at a low temperature. The nanolaminate serves as a thin-film encapsulation layer for OLEDs. The reaction mechanism of PEALD process was investigated using an in-situ quartz crystal microbalance (QCM) and in-situ quadrupole mass spectrometer (QMS)...
January 6, 2017: Scientific Reports
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