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Plasma light

Michelle Hershman, Raymond Carmody, Unni K Udayasankar
History A 19-year-old woman with no pertinent medical history was brought to the emergency department after being found unconscious on her bathroom floor by her roommate. In the preceding weeks, she had reported intractable nausea and vomiting, for which she had been taking ondansetron. No other medications had been prescribed. The day prior to presentation, she had contacted her mother and described increasing confusion. Glasgow coma scale score on arrival in the emergency department was 4. Intravenous naloxone was administered, without immediate response...
April 2018: Radiology
Zbyszko Chowaniec, Anna Skoczyńska
Cardiovascular diseases are still the main cause of death in Poland and throughout the world. Independent risk factors of cardiovascular disease, in addition to elevated LDL cholesterol, are both low HDL levels and high levels of non-HDL cholesterol. Plasma phospholipid-transfer protein (PLTP) and cholesteryl ester transfer protein (CETP) both play a major role in the metabolism of those lipoproteins. A lack of these proteins increases HDL and lowers LDL levels. In the light of current knowledge, it seems reasonable to search for compounds that may decrease the activity of CETP, and thus reduce the incidence of cardiovascular disease...
March 16, 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
Divyen K Shah, Vennila Ponnusamy, Jane Evanson, Olga Kapellou, Georgia Ekitzidou, Neelam Gupta, Paul Clarke, Adina T Michael-Titus, Ping K Yip
Aims and hypothesis: Hypoxic-ischemic encephalopathy (HIE) remains an important cause of death and disability in newborns. Mild therapeutic hypothermia (TH) is safe and effective; however, there are no tissue biomarkers available at the bedside to select babies for treatment. The aim of this study was to show that it is feasible to study plasma neurofilament light (NfL) levels from newborns and to evaluate their temporal course. Hypothesis: Raised plasma NFL protein levels from newborns who undergo TH after HIE are associated with abnormal MRI outcomes...
2018: Frontiers in Neurology
Vladimir S Shavva, Alexandra M Bogomolova, Alexander M Efremov, Alexander N Trofimov, Artemy A Nikitin, Anna V Babina, Ekaterina V Nekrasova, Ella B Dizhe, Galina N Oleinikova, Boris V Missyul, Sergey V Orlov
C3 is an acute phase protein, and thus its plasma concentration increases quickly and drastically during the onset of inflammation. Insulin plays a complex role in inflammation. Elevated level of plasma C3 was shown to correlate with heightened fasting insulin levels and insulin resistance and appears to be a risk factor for the cardiovascular disease and atherosclerosis. The main source of plasma C3 is liver. Nothing is known about effects of insulin on C3 gene expression and protein secretion by hepatocytes...
March 9, 2018: European Journal of Cell Biology
Kazuhiro Yanagi, Ryotaro Okada, Yota Ichinose, Yohei Yomogida, Fumiya Katsutani, Weilu Gao, Junichiro Kono
Confined electrons collectively oscillate in response to light, resulting in a plasmon resonance whose frequency is determined by the electron density and the size and shape of the confinement structure. Plasmons in metallic particles typically occur in the classical regime where the characteristic quantum level spacing is negligibly small compared to the plasma frequency. In doped semiconductor quantum wells, quantum plasmon excitations can be observed, where the quantization energy exceeds the plasma frequency...
March 16, 2018: Nature Communications
Lesley W Chan, Daniel E Morse, Michael J Gordon
Near- and sub-wavelength photonic structures are used by numerous organisms (e.g., insects, cephalopods, fish, birds) to create vivid and often dynamically-tunable colors, as well as create, manipulate, or capture light for vision, communication, crypsis, photosynthesis, and defense. This review introduces the physics of moth eye (ME)-like, biomimetic nanostructures and discusses their application to reduce optical losses and improve efficiency of various optoelectronic devices, including photodetectors, photovoltaics, imagers, and light emitting diodes...
March 16, 2018: Bioinspiration & Biomimetics
Ji Yong Choi, Cheol Young Choi
This study was conducted to identify the possible effect of recombinant vertebrate ancient long (VAL) opsin as a non-visual "photoreceptor" in the deep brain of goldfish, Carassius auratus. In addition, we investigated the effects of green-wavelength light on the predictable reproductive function of VAL-opsin as a green-sensitive pigment in the deep brain. To determine this, we quantified changes in gonadotropin hormone (GTH) [GTHα, follicle stimulating hormone (FSH) and luteinizing hormone (LH)] and estrogen receptor (ER; ERα and ERβ) mRNA expression levels associated with goldfish reproduction as well as changes in plasma FSH, LH, and 17β-estradiol (E2 ) activities after injection of recombinant VAL-opsin protein in two concentrations (0...
March 14, 2018: Fish Physiology and Biochemistry
Xiangmin Zhang, Xiangfu Zeng, Lianbin Liu, Xiaolin Lan, Jing Huang, Hongxue Zeng, Rong Li, Keqing Luo, Wei Wu, Maohua Zhou, Shaojin Li
The concentration and distribution of rare earth elements (REE) in nasopharyngeal carcinoma (NPC) were measured to investigate connections with tumor size, lymph node metastasis, clinical stages, and Epstein-Barr virus (EBV) infection. There were 30 patients with NPC who met the criteria for inclusion in the present study. The EBV copy number, as well as the concentration and distribution of REE, was analyzed. EBV was detected using reverse transcription-polymerase chain reaction, with the concentrations of REE in NPC tissues measured using inductively coupled plasma-tandem mass spectrometry...
April 2018: Oncology Letters
Cristina Di Poto, Shisi He, Rency S Varghese, Yi Zhao, Alessia Ferrarini, Shan Su, Abdullah Karabala, Mesfin Redi, Hassen Mamo, Amol S Rangnekar, Thomas M Fishbein, Alexander H Kroemer, Mahlet G Tadesse, Rabindra Roy, Zaki A Sherif, Deepak Kumar, Habtom W Ressom
Disparities in hepatocellular carcinoma (HCC) incidence and survival have been observed between ethnic groups including African-Americans (AA) and European-Americans (EA). The evaluation of the changes in the levels of metabolites in samples stratified by race could provide a snapshot of ethnically diverse disease related pathways and identify reliable biomarkers. In this study, we considered AA and EA to investigate metabolites that may be associated with HCC in a race-specific manner. The levels of 46 metabolites in plasma samples, collected from patients recruited at MedStar Georgetown University Hospital, were analyzed by Agilent GC-qMS in selected ion monitoring (SIM) mode...
2018: PloS One
Yue Yang, Long Chen, Yuan Jia, Yang Liu, Lei Wen, Yaoxian Liang, Yuan An, Shi Chen, Yin Su, Zhanguo Li
To analyze the clinical spectrum, laboratory characteristics, and outcomes of monoclonal gammopathy (MG) in patients with rheumatic diseases. Screening for the presence of MG was performed in 872 inpatients with rheumatic diseases from January 2010 to July 2017. A total of 41 patients were enrolled. Their clinical and biological features in addition to outcomes were described. For each patient with primary Sjögren syndrome (pSS), 2 age- and sex-matched pSS patients without MG were selected as controls. Risk factors for the presence of MG and malignant hematological neoplasias were assessed...
March 13, 2018: Clinical Rheumatology
Haruko Tashiro, Ryosuke Shirasaki, Masato Watanabe, Kazuo Kawasugi, Yoshihisa Takahashi, Naoki Shirafuji
We present a lymphoplasmacytic lymphoma patient with Factor X (FX) deficiency. Despite the absence of FX inhibitor, the administration of fresh frozen plasma and anti-inhibitor coagulant complex did not increase the FX level. The autopsy showed that massive amyloid depositions to multiple organs and FX existed in union with amyloidosis.
March 2018: Clinical Case Reports
Paolo Milani, Giampaolo Merlini, Giovanni Palladini
Light chain (AL) amyloidosis is caused by a usually small plasma-cell clone that is able to produce the amyloidogenic light chains. They are able to misfold and aggregate, deposit in tissues in the form of amyloid fibrils and lead to irreversible organ dysfunction and eventually death if treatment is late or ineffective. Cardiac damage is the most important prognostic determinant. The risk of dialysis is predicted by the severity of renal involvement, defined by the baseline proteinuria and glomerular filtration rate, and by the response to therapy...
2018: Mediterranean Journal of Hematology and Infectious Diseases
Jean Amiral, Maxime Laroche, Jerard Seghatchian
For many years, the importance of fibrinolysis has been recognized, first for its intravascular antithrombotic action, and more recently for its many extravascular activities, associated with matrix degradation and tissue remodeling. In the blood circulation system, fibrinolysis prevents thrombosis, and is associated with various biological and clinical situations: risk factors for cardio-vascular diseases in high risk clinical situations (type II diabetes, hypertension, triglycerides, high BMI, elevated glucose, etc...
February 20, 2018: Transfusion and Apheresis Science
Bérénice Jahn, Arjan Pol, Henning Lumpe, Thomas Barends, Andreas Dietl, Carmen Hogendoorn, Huub Op den Camp, Lena Daumann
Since the discovery of the biological relevance of rare earth elements (REE) for numerous different bacteria, the questions of the advantage of REE in the active site of methanol dehydrogenase (MDH) over calcium(II) and why bacteria prefer light REE have been a subject of debate. Here we report the cultivation and purification of the strictly REE-dependent methanotrophic bacterium Methyl-acidiphilum fumariolicum SolV with europium(III) as well as structural and kinetic analyses of the first Eu-substituted methanol dehydrogenase...
March 10, 2018: Chembiochem: a European Journal of Chemical Biology
Miriam Steinberg, Joseph P Gaut, Stanley Paul Hmiel, Aadil Kakajiwala
Monoclonal gammopathies are a rare diagnosis in pediatric patients. A 19-year-old female patient with past medical history of hypogammaglobulinemia and natural killer cell deficiency and stage III follicular lymphoma, in remission, presented with a right-sided pneumonia, noted to have acute kidney injury and proteinuria. Complement C3 and C4 levels were normal. Anti-double-stranded DNA antibodies, antinuclear antibodies, anti-extractable nuclear antigen antibodies, and antineutrophil cytoplasmic antibodies were negative...
March 9, 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
Roseli Soncini, Joseana Vieira, Ana Carolina Ramos Lopes, Silvia Graciela Ruginsk, Erika K Incerpi, Angel Roberto Barchuk
Glucocorticoids (GCs) are used for acute respiratory distress syndrome (ARDS) to improve or prevent lung injury. The mechanisms underlying the effects of GCs involve inadequate GC-receptor (GR)-mediated downregulation of pro-inflammatory factors despite elevated levels of cortisol. Within this context, knowledge of the transcriptional pattern of the GR gene in response to variations in physiological parameters may shed light on this issue. We addressed this problem by measuring plasmatic corticosterone (CCT) levels and assessing GR expression at transcript and protein levels in rats with caecal ligation and puncture (CLP)-induced ARDS-like syndrome treated with dexamethasone and metyrapone...
March 6, 2018: Molecular and Cellular Endocrinology
Francesco Martelli, Jessica Mencarini, Arianna Rocca, Nunzia Della Malva, Dario Bartolozzi, Simone Giannecchini
Current evidence suggests that Polyomavirus (PyV) microRNAs (miRNAs) circulating in biological fluids may be relevant to understanding viral persistence. Here, the expression of polyomavirus BKPyV, JCPyV, MCPyV and SV40 miRNAs in saliva was investigated to evaluate PyV prevalence/persistence in the oral cavity. PyV-DNA status and PyV-miRNA expression was examined in paired saliva and plasma samples of 100 HIV-infected patients and of 50 healthy subjects using digital droplet PCR and PyV-miRNA-5p stem-loop RT-PCR...
March 5, 2018: Virus Research
Sung Hyun Kim, Mac Kim, Jae Heung Lee, Sang-Jin Lee
This paper proposes a novel self-cleaning transparent heat mirror (SC-THM) produced by depositing a plasma polymer fluorocarbon thin film on a silver-and-SiNx multilayer structure fabricated by continuous roll-to-roll sputtering. The optimal structure and thickness of each thin film of three-layer and five-layer SC-THM were derived from optical simulation. In the five-layer SC-THM, the visible light transmittance was 60.67% at a wavelength of 406 nm, and the infrared (IR) transmittance was 6.86% at a 1,000-nm wavelength and 2...
March 8, 2018: ACS Applied Materials & Interfaces
Xue-Na Zheng, Jun Yang, Tao Xie, Bin Guo, Zhi-Qiang Xie, Li-Na Xie, Xue-Fen Wu, Gang-Zhu Hu, Mai-Lan Liu, Zeng-Hui Yue
OBJECTIVE: To observe the effect of herbal cake-separated moxibustion on blood lipid-apoprotein levels and the expression of Toll-like receptor 2 (TLR 2), TLR 4 and nuclear factor kappa B(NF-κB) mRNAs in atherosclerotic (AS) vulnerable plaques of hyperglycemia rabbits, so as to explore its mechanism underlying improvement of atherosclerosis. METHODS: Sixty New Zealand rabbits were randomly divided into 5 groups: control, model, direct moxibustion, herbal-cake-separated moxibustion and medication groups( n =12 rabbits in each group)...
February 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
Haihua Zhang, Qing Liao, Yishi Wu, Zhaoyi Zhang, Qinggang Gao, Peng Liu, Meili Li, Jiannian Yao, Hongbing Fu
3D organic-inorganic hybrid perovskites have featured high gain coefficients through the electron-hole plasma stimulated emission mechanism, while their 2D counterparts of Ruddlesden-Popper perovskites (RPPs) exhibit strongly bound electron-hole pairs (excitons) at room temperature. High-performance solar cells and light-emitting diodes (LEDs) are reported based on 2D RPPs, whereas light-amplification devices remain largely unexplored. Here, it is demonstrated that ultrafast energy transfer along cascade quantum well (QW) structures in 2D RPPs concentrates photogenerated carriers on the lowest-bandgap QW state, at which population inversion can be readily established enabling room-temperature amplified spontaneous emission and lasing...
March 8, 2018: Advanced Materials
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