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https://www.readbyqxmd.com/read/28823086/an-efficient-fluorescence-turn-on-chemosensor-comprising-of-coumarin-and-rhodamine-moieties-for-al-3-and-hg-2
#1
Samik Acharyya, Saswati Gharami, Lakshman Patra, Tapan Kumar Mondal
A potent fluorescence 'turn-on' receptor (HL) based on rhodamine and coumarin moieties for the detection of Hg(2+) and Al(3+) is synthesized by condensation of rhodamine 6G hydrazide and 4-hydroxy-3-acetylcoumarin. In presence of Al(3+) and/or Hg(2+) the receptor (HL) exhibits deep pink colouration and a sharp band at 528 nm is appeared in UV-vis titration. Upon gradual addition of Al(3+) and/or Hg(2+) to the solution of HL significant enhancement of fluorescence intensity is observed at 564 nm in MeCN:H2O (1:5, v/v) medium...
August 19, 2017: Journal of Fluorescence
https://www.readbyqxmd.com/read/28823068/stress-affects-surface-glycoconjugates-of-the-rat-endometrium-at-the-time-of-implantation
#2
Elham Aliabadi, Zohreh Makoolati, Tahereh Talaei-Khozani, Fakhreddin Mesbah Ardekani
One of the treatments to infertility is In Vitro Fertilization (IVF). In the course of IVF, fertilization rate can be improved through stress reduction. Probably one of the causes of low outcome of IVF is changes in uterine glycoconjugates that are first site of contact between blastocyst and uterus, due to stress, e.g., stress of injection. Thus, the study of the injectional stress effects on implantation period is very important to improve the outcome of IVF. Sixteen mature female rats were divided to experimental and control groups...
August 19, 2017: Glycoconjugate Journal
https://www.readbyqxmd.com/read/28823032/luminescent-benzothiazole-based-fluorophore-of-anisidine-scaffoldings-a-turn-on-fluorescent-probe-for-al-3-and-hg-2-ions
#3
Gargi Dhaka, Navneet Kaur, Jasvinder Singh
A new anisidine possessing benzothiaozle-based chemosensor (1) has been designed and synthesized. The chemosensor 1 was designed to provide hard base environment for ratiometric detection of comparatively less studied Al(3+) ions. In CH3CN, the fluorescence spectra of chemosensor 1 red shifted from 368 to 430 nm with addition of Al(3+) and Hg(2+) ions; while Cu(2+) ions caused quenching of emission intensity of 1. These differential changes observed with Al(3+) and Cu(2+) ions addition enabled chemosensor 1 to construct "NOR" and "TRANSFER" logic gates...
August 19, 2017: Journal of Fluorescence
https://www.readbyqxmd.com/read/28823018/prevalence-and-nature-of-potential-drug-drug-interactions-among-kidney-transplant-patients-in-a-german-intensive-care-unit
#4
Julia Amkreutz, Alexander Koch, Lukas Buendgens, Anja Muehlfeld, Christian Trautwein, Albrecht Eisert
Background Complex polypharmacotherapy makes kidney transplant patients vulnerable to drug-drug interactions (DDIs). Objective To study prevalence and nature of potential DDIs (pDDIs) in kidney transplant patients. Setting Internal medicine ICU, University Hospital RWTH Aachen. Method In this retrospective observational study, pDDIs were identified in the first week after transplant from 1999 to 2010. Patients aged at least 18 years with prescription of at least two drugs were included. Patients with incomplete data were excluded...
August 19, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28823014/assessment-of-the-quality-of-the-harran-plain-soils-under-long-term-cultivation
#5
Ali Volkan Bilgili, Çiğdem Küçük, Harold M Van Es
Soil quality refers to the ability of soils to perform their functions well. The soils of the Harran Plain, Turkey, have been put into intensive crop production with the introduction of an irrigation scheme and become increasingly degraded due to unsustainable management and cropping systems that resulted in the loss of production potential. The goal of this study was to quantify the quality of common soil series in the Plain using soil quality indexes (SQI) and to compare SQIs of two long-term crop rotations, cotton and wheat-corn cultivation, and different soil types...
August 19, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28823008/neuropathic-pain-s-biopsychosocial-effects
#6
Esra Dogru Huzmeli, Ismet Melek
The aim of our study is to understand neuropathic pain's social, psychological, and biological effects on the patients. All of the patients who were diagnosed with neuropathic pain (NP) by a neurologist were invited to participate in the study. The diagnoses were made based on the patients' history and symptoms and the results of their neurological examinations. Demographic characteristics (age and pain duration), diagnoses, and medical histories of the patients were recorded. Average daily pain intensity was measured using a 100-mm visual analogue scale (VAS)...
August 19, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28822935/assessing-urban-population-vulnerability-and-environmental-risks-across-an-urban-area-during-heatwaves-implications-for-health-protection
#7
H L Macintyre, C Heaviside, J Taylor, R Picetti, P Symonds, X-M Cai, S Vardoulakis
Heatwaves can lead to a range of adverse impacts including increased risk of illness and mortality; the heatwave in August 2003 has been associated with ~70,000 deaths across Europe. Due to climate change, heatwaves are likely to become more intense, more frequent and last longer in the future. A number of factors may influence risks associated with heat exposure, such as population age, housing type, and location within the Urban Heat Island, and such factors may not be evenly distributed spatially across a region...
August 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28822903/uterine-clinical-findings-fertility-rate-leucocyte-migration-and-cox-2-protein-levels-in-the-endometrial-tissue-of-susceptible-mares-treated-with-platelet-rich-plasma-before-and-after-ai
#8
Lorenzo G Segabinazzi, Aime M Friso, Sebastian B Correal, André M Crespilho, José Antonio Dell'Aqua, Jordi Miró, Frederico O Papa, Marco Antonio Alvarenga
Persistent mating-induced endometritis (PMIE) results in decreased fertility in horses, thereby causing a significant impact in the horse market. Platelet-rich plasma (PRP), a modulator of the inflammatory response, has been largely used in veterinary medicine. Here, we investigated the effects of PRP on uterine inflammation, conception rate, endometrial polymorphonuclear neutrophil (PMN) migration, and COX-2 protein levels in the endometrial tissue. Thirteen PMIE-susceptible mares were used for artificial insemination (AI)...
August 12, 2017: Theriogenology
https://www.readbyqxmd.com/read/28822891/comparative-toxicity-of-the-plasticizer-dibutyl-phthalate-to-two-freshwater-algae
#9
Shurui Gu, Hao Zheng, Qingqing Xu, Cuizhu Sun, Mei Shi, Zhenyu Wang, Fengmin Li
Phthalate esters (PAEs), a family of emerging environmental contaminants, have been frequently detected in soils and water. However, intensive studies on the toxicity of PAEs have focused on growth response of terrestrial and aquatic animals, while only limited attention has been paid to aquatic plants, especially phytoplankton, the primary producer in aquatic ecosystems. Therefore, the acute toxic effects and underlying mechanisms of dibutyl phthalate (DBP) at different concentrations (0-20mgL(-1)) on two typical freshwater algae (Scenedesmus obliquus and Chlorella pyrenoidosa) were investigated...
August 12, 2017: Aquatic Toxicology
https://www.readbyqxmd.com/read/28822886/concurrent-spectrometry-of-annihilation-radiation-and-characteristic-gamma-rays-for-activity-assessment-of-selected-positron-emitters
#10
S G Dolley, G F Steyn, T J van Rooyen, F Szelecsényi, Z Kovács, C Vermeulen, N P van der Meulen
A method is described to determine the activity of non-pure positron emitters in a radionuclide production environment by assessing the 511keV annihilation radiation concurrently with selected γ-lines, using a single High-Purity Germanium (HPGe) detector. Liquid sources of (22)Na, (52)Fe, (52m)Mn, (61)Cu, (64)Cu, (65)Zn, (66)Ga, (68)Ga, (82)Rb, (88)Y, (89)Zr and (132)Cs were prepared specifically for this study. Acrylic absorbers surrounding the sources ensured that the emitted β(+)-particles could not escape and annihilate away from the source region...
August 1, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28822854/involvement-of-cyclic-nucleotide-gated-channels-in-spontaneous-activity-generated-in-isolated-interstitial-cells-of-cajal-from-the-rabbit-urethra
#11
Maria Sancho, Eamonn Bradley, Angeles Garcia-Pascual, Domingo Triguero, Keith D Thornbury, Mark A Hollywood, Gerard P Sergeant
Cyclic nucleotide-gated (CNG) channels are non-selective cation channels that mediate influx of extracellular Na(+) and Ca(2+) in various cell types. L-cis-Diltiazem, a CNG channel blocker, inhibits contraction of urethral smooth muscle (USM), however the mechanisms underlying this effect are still unclear. We investigated the possibility that CNG channels contribute to spontaneous pacemaker activity in freshly isolated interstitial cells of Cajal (ICC) isolated from the rabbit urethra (RUICC). Using immunocytochemistry, we found intense CNG1-immunoreactivity in vimentin-immunoreactive RUICC, mainly within patches of the cellular body and processes...
August 16, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28822844/a-ph-sensitive-methenamine-mandelate-loaded-nanoparticle-induces-dna-damage-and-apoptosis-of-cancer-cells
#12
Linhua Zhang, Wenbo Hao, Lv Xu, Yongfeng Gao, Xusheng Wang, Dunwan Zhu, Zhuo Chen, Xudong Zhang, Hongbo Chen, Lin Mei
Methenamine mandelate is a urinary antibacterial agent, which can be converted to formaldehyde in urine that has a relatively low pH of average 5.5-6.8. Here, we prepare a pH-sensitive PLGA-based nanoparticle containing both methenamine mandelate and NaHCO3. Methenamine mandelate/NaHCO3-coloaded nanoparticle could enter cells via endosome/lysosome pathway. The pH in lysosomes and endo-lysosomes is approximately 5.0. In the acidic environment, NaHCO3 reacts with proton and produce CO2 bubbles, which burst nanoparticles and lead to the rapidly release of methenamine mandelate...
August 16, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28822815/enrichment-of-highly-settleable-microalgal-consortia-in-mixed-cultures-for-effluent-polishing-and-low-cost-biomass-production
#13
Yuansheng Hu, Xiaodi Hao, Mark van Loosdrecht, Huiqin Chen
Microalgae cultivation is a promising technology for integrated effluent polishing and biofuel production, but poor separability of microalgal cells hinders its industrial application. This study intended to selectively enrich settleable microalgal consortia in mixed culture by applying "wash-out" pressure, which was realized by controlling settling time (ST) and volume exchange ratio (VER) in photo-SBRs. The results demonstrated that highly settleable microalgal consortia (settling efficiency>97%; SVI = 17-50 mL/g) could be enriched from indigenous algal cultures developed in WWTP's effluent...
August 15, 2017: Water Research
https://www.readbyqxmd.com/read/28822814/assessment-of-drinking-water-quality-at-the-tap-using-fluorescence-spectroscopy
#14
Masoumeh Heibati, Colin A Stedmon, Karolina Stenroth, Sebastien Rauch, Jonas Toljander, Melle Säve-Söderbergh, Kathleen R Murphy
Treated drinking water may become contaminated while travelling in the distribution system on the way to consumers. Elevated dissolved organic matter (DOM) at the tap relative to the water leaving the treatment plant is a potential indicator of contamination, and can be measured sensitively, inexpensively and potentially on-line via fluorescence and absorbance spectroscopy. Detecting elevated DOM requires potential contamination events to be distinguished from natural fluctuations in the system, but how much natural variation to expect in a stable distribution system is unknown...
August 8, 2017: Water Research
https://www.readbyqxmd.com/read/28822777/managing-the-course-of-diabetic-kidney-disease-from-the-old-to-the-new
#15
REVIEW
Ronald M Goldenberg, Murray Berall, Christopher T M Chan, David Z I Cherney, Julie A Lovshin, Philip A McFarlane, Peter A Senior, Subodh Verma, Jordan J Weinstein
Diabetic kidney disease (DKD) is a group of chronic kidney diseases that is associated with significant cardiovascular as well as all-cause morbidity and mortality. Although DKD is often progressive in nature, its evolution can be modified by intensive management of glycemia and blood pressure and inhibition of the renin-angiotensin-aldosterone system. This review provides an overview of how multifactorial interventions can provide renal protection and includes a discussion of the nonglycemic effects of incretin-based diabetes therapies (glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase 4 inhibitors) and sodium-glucose cotransporter-2 inhibitors within the kidney in patients with type 2 diabetes...
August 16, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28822735/-the-care-of-skin-lesions-caused-by-extravasation-of-intravenous-fluids-in-peripheral-venous-perfusion
#16
C Ly
INTRODUCTION: Infiltration and extravasation account for 23-78 % of the complications stemming from peripheral venous perfusions in neonatal intensive care units. Their consequences, sometimes dramatic, can be pain, infections, or even loss of skin, which can lead to nerve and/or muscle damage, particularly severe for preterm neonates. Today there are no recommendations on the care of these lesions, which can lead to an erroneous choice or to a delay in the possible treatments. OBJECTIVE: This review of the literature aims to explore and propose elements of therapeutic care collected in the scientific literature...
August 16, 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28822719/thalidomide-is-associated-with-increased-t-cell-activation-and-inflammation-in-antiretroviral-naive-hiv-infected-individuals-in-a-randomised-clinical-trial-of-efficacy-and-safety
#17
Tânia R C Vergara, Sadia Samer, Joanna R Santos-Oliveira, Leila B Giron, Muhammad Shoaib Arif, Maria Luciana Silva-Freitas, Lia A Cherman, Mauro S Treitsman, Alberto Chebabo, Maria Cecilia A Sucupira, Alda M Da-Cruz, Ricardo Sobhie Diaz
TRIAL DESIGN: Open-label, randomised, controlled, pilot proof-of-concept clinical trial. METHODS: Participants: Antiretroviral naïve adult males with CD4 count ≥350cells/mm(3). INTERVENTIONS: Patients were randomised to receive thalidomide 200mg QD for 3weeks (Thalidomide group) or not (Control group) and followed for 48weeks. OBJECTIVE: We hypothesized that short-term Thalidomide use would reduce HIV related inflammation and HIV replication among antiretroviral naïve HIV infected individuals...
August 12, 2017: EBioMedicine
https://www.readbyqxmd.com/read/28822705/anti-dermatophyte-activity-of-leguminosae-plants-from-southern-brazil-with-emphasis-on-mimosa-pigra-leguminosae
#18
C B de Morais, M Scopel, G P R Pedrazza, F K da Silva, D F Dalla Lana, M L Tonello, S T S Miotto, M M Machado, L F S De Oliveira, A M Fuentefria, J A S Zuanazzi
BACKGROUND: Intensive prophylactic use of antifungals leads to the increase of drug resistance and the need for new and more effective treatments are real. Plants from Leguminosae family are rich in flavonoids, for which numerous biological activities have been described, including antifungal effects. PURPOSE: To screen methanolic extracts from Leguminosae species looking for alternative sources for antifungal agents (anti-dermatophyte and anti-Candida) and their innocuity...
August 16, 2017: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/28822608/predictors-of-mortality-in-adults-with-sickle-cell-disease-admitted-to-intensive-care-unit-in-bahrain
#19
Sana Abdulaziz Al Khawaja, Zainab Mahdi Ateya, Ridha Abdulla Al Hammam
No abstract text is available yet for this article.
August 15, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28822530/application-of-exercise-ecg-stress-test-in-the-current-high-cost-modern-era-healthcare-system
#20
REVIEW
Gaurang Nandkishor Vaidya
Exercise electrocardiogram (ECG) tests boasts of being more widely available, less resource intensive, lower cost and absence of radiation. In the presence of a normal baseline ECG, an exercise ECG test is able to generate a reliable and reproducible result almost comparable to Technitium-99m sestamibi perfusion imaging. Exercise ECG changes when combined with other clinical parameters obtained during the test has the potential to allow effective redistribution of scarce resources by excluding low risk patients with significant accuracy...
July 2017: Indian Heart Journal
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