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https://www.readbyqxmd.com/read/29778832/glucocorticoid-metabolites-in-newborns-a-marker-for-traffic-noise-related-stress
#1
Manuella Lech Cantuaria, Jakob Usemann, Elena Proietti, Victoria Blanes-Vidal, Bernhard Dick, Christa E Flück, Simone Rüedi, Harris Héritier, Jean-Marc Wunderli, Philipp Latzin, Urs Frey, Martin Röösli, Danielle Vienneau
BACKGROUND: Traffic noise has been associated with an increased risk for several non-auditory health effects, which may be explained by a noise-induced release of stress hormones (e.g. glucocorticoids). Although several studies in children and adults have indicated an increased secretion of glucocorticoids after exposure to noise, information regarding newborns is scarce. OBJECTIVES: To investigate the association between residential exposure to road traffic noise and postnatal stress response, as assessed by the concentration of glucocorticoids at five weeks of age...
May 17, 2018: Environment International
https://www.readbyqxmd.com/read/29775873/psychosocial-stress-and-inflammation-driving-tryptophan-breakdown-in-children-and-adolescents-a-cross-sectional-analysis-of-two-cohorts
#2
Nathalie Michels, Gerard Clarke, Loreto Olavarria-Ramirez, Sonia Gómez-Martínez, Ligia Esperanza Díaz, Ascensión Marcos, Kurt Widhalm, Livia A Carvalho
BACKGROUND: Tryptophan breakdown is an important mechanism in several diseases e.g. inflammation and stress-induced inflammation have been associated with the development of depression via enhanced tryptophan breakdown. Depression is a major public health problem which commonly starts during adolescence, thus identifying underlying mechanisms during early life is crucial in prevention. The aim of this work was to verify whether independent and interacting associations of psychosocial stress and inflammation on tryptophan breakdown already exist in children and adolescents as a vulnerable age group...
May 15, 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29742755/family-socioeconomic-status-cortisol-and-physical-health-in-early-childhood-the-role-of-advantageous-neighborhood-characteristics
#3
Danielle S Roubinov, Melissa J Hagan, W Thomas Boyce, Nancy E Adler, Nicole R Bush
OBJECTIVE: Children from families with lower socioeconomic status (SES) evidence greater physiological dysregulation and poorer health. Despite recognition of environmental contributors, little is known about the influence of neighborhood characteristics. The present study examined the moderating role of community-level risks and resources on the relation of family SES to children's daily cortisol output and physical health during the kindergarten year. METHODS: In fall and spring of kindergarten, children's (n = 338) daily total cortisol was measured and parents and teachers rated children's global physical health...
May 7, 2018: Psychosomatic Medicine
https://www.readbyqxmd.com/read/29733496/children-s-stress-related-reports-and-stress-biomarkers-interact-in-their-association-with-metabolic-syndrome-risk
#4
Nathalie Michels, Dante Matthys, Barbara Thumann, Staffan Marild, Stefaan De Henauw
The purpose was to examine the cross-sectional associations of stress-related reports and stress biomarkers with metabolic syndrome (MetS) risk in children while also testing the interaction between stress biomarkers and stress reports. In 353 children (5-10 years old, 7.9% overweight/obese), MetS risk was measured by blood pressure, waist circumference, glucose homeostasis, triglycerides, and high-density cholesterol. Stress was measured by stress-related reports (events, emotions, and internalizing/externalizing problems) and two biomarkers: salivary cortisol (total-day and morning output) and heart rate variability (percentage of consecutive normal RR intervals differing more than 50 ms and low-to-high-frequency ratio)...
May 7, 2018: Stress and Health: Journal of the International Society for the Investigation of Stress
https://www.readbyqxmd.com/read/29731943/anxiety-stress-and-coping-patterns-in-children-in-dental-settings
#5
REVIEW
Nadica Pop-Jordanova, Olivera Sarakinova, Maja Pop-Stefanova-Trposka, Efka Zabokova-Bilbilova, Emilija Kostadinovska
BACKGROUND: Fear of the dentist and dental treatment is a common problem. It can cause treatment difficulties for the practitioner, as well as severe consequences for the patient. As is known, the level of stress can be evaluated thought electrodermal activity, cortisol measure in saliva, or indirectly by psychometric tests. AIM: The present study examined the psychological influence of dental interventions on the child as well as coping patterns used for stress diminution...
April 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29729024/enduring-association-between-parenting-and-cortisol-a-meta-analysis
#6
REVIEW
Daniel A Hackman, Jacqueline R O'Brien, Maureen Zalewski
Warm caregiving is associated with concurrent hypothalamic-pituitary-adrenocortical (HPA) axis function, although the persistence of this association over time is less established. Using longitudinal and intervention studies, this meta-analysis examined the enduring association of parental warmth (measured when children were ages < 1 through 15 years) with basal cortisol, reactivity and recovery (measured when children were ages < 1 through 25 years; k = 38; N = 6,608). These studies demonstrate no overall associations between parenting and children's HPA axis; instead there are small associations that vary based on moderators such as socioeconomic status, developmental stage, study design and stressor type, though many moderators are confounded...
May 5, 2018: Child Development
https://www.readbyqxmd.com/read/29727766/ameliorating-the-biological-impacts-of-childhood-adversity-a-review-of-intervention-programs
#7
REVIEW
Sukhdip K Purewal Boparai, Vanessa Au, Kadiatou Koita, Debora Lee Oh, Susan Briner, Nadine Burke Harris, Monica Bucci
Childhood adversity negatively impacts the biological development of children and has been linked to poor health outcomes across the life course. The purpose of this literature review is to explore and evaluate the effectiveness of interventions that have addressed an array of biological markers and physical health outcomes in children and adolescents affected by adversity. PubMed, CINAHL, PsychInfo, Sociological Abstracts databases and additional sources (Cochrane, WHO, NIH trial registries) were searched for English language studies published between January 2007 and September 2017...
May 1, 2018: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29723234/protecting-the-child-while-preserving-the-relationship-using-baby-s-relational-withdrawal-to-gauge-the-effect-of-parental-visitation
#8
Alexandra Deprez, Jaqueline Wendland, Line Brotnow, Arno C Gutleb, Servane Contal, Antoine Guédeney
The impact of children's interactions with parents in the context of out-of-home placements is receiving much-needed cross-disciplinary attention. However, the paucity of instruments that can reliably represent young children's experiences of such interactions precludes a nuanced evaluation of their impact on wellbeing and development. In response to this empirical gap, the present study investigates children's relational withdrawal as a clinically salient, easily observable and conceptually valid measure of infants' and toddlers' responses to parents...
2018: PloS One
https://www.readbyqxmd.com/read/29709497/reduced-cortical-excitability-neuroplasticity-and-salivary-cortisol-in-11-13-year-old-children-born-to-women-with-gestational-diabetes-mellitus
#9
Jago M Van Dam, Amy J Garrett, Luke A Schneider, Nicolette A Hodyl, Mitchell R Goldsworthy, Suzette Coat, Janet A Rowan, William M Hague, Julia B Pitcher
BACKGROUND: Children exposed to gestational diabetes mellitus (GDM) in utero are at increased risk of neurodevelopmental difficulties, including autism and impaired motor control. However, the underlying neurophysiology is unknown. METHODS: Using transcranial magnetic stimulation, we assessed cortical excitability, long-term depression (LTD)-like neuroplasticity in 45 GDM-exposed and 12 control children aged 11-13 years. Data were analysed against salivary cortisol and maternal diabetes severity and treatment (insulin [N = 22] or metformin [N = 23]) during pregnancy...
April 10, 2018: EBioMedicine
https://www.readbyqxmd.com/read/29705575/putting-a-finger-on-the-problem-finger-stick-blood-draw-and-immunization-at-the-well-child-exam-elicit-a-cortisol-response-to-stress-among-one-year-old-children
#10
Darlene A Kertes, Hayley S Kamin, Jingwen Liu, Samarth S Bhatt, Maria Kelly
Research examining stress reactivity of the hypothalamic-pituitary-adrenocortical (HPA) axis in young children has historically been hampered by a lack of reliable methods to invoke a cortisol stress response. This report details an effective method of eliciting a cortisol rise in one-year-old children (N = 83) by modifying and combining two naturalistic stressors previously used with infants and children. Salivary cortisol levels were collected from children before and after a finger stick blood draw and immunizations performed during their one year well-child checkup at their pediatrician's office...
April 22, 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29705502/social-group-dynamics-predict-stress-variability-among-children-in-a-new-zealand-classroom
#11
Julie Spray, Bruce Floyd, Judith Littleton, Susanna Trnka, Siobhan Mattison
Previous research proposes stress as a mechanism for linking social environments and biological bodies. In particular, non-human primate studies investigate relationships between cortisol as a measure of stress response and social hierarchies. Because human social structures often include hierarchies of dominance and social status, humans may exhibit similar patterns. Studies of non-human primates, however, have not reached consistent conclusions with respect to relationships between social position and levels of cortisol...
March 27, 2018: Homo: Internationale Zeitschrift Für die Vergleichende Forschung Am Menschen
https://www.readbyqxmd.com/read/29696788/delayed-peak-response-of-cortisol-to-insulin-tolerance-test-in-patients-with-prader-willi-syndrome
#12
Yuji Oto, Keiko Matsubara, Tadayuki Ayabe, Masahisa Shiraishi, Nobuyuki Murakami, Hiroshi Ihara, Tomoyo Matsubara, Toshiro Nagai
Deaths among children with Prader-Willi syndrome (PWS) are often related to only mild or moderate upper respiratory tract infections, and many causes of death remain unexplained. Several reports have hypothesized that patients with PWS may experience latent central adrenal insufficiency. However, whether PWS subjects suffer from alteration of the hypothalamus-pituitary-adrenal (HPA) axis remains unclear. This study aimed to explore the HPA axis on PWS. We evaluated the HPA axis in 36 PWS patients (24 males, 12 females; age range, 7 months to 12 years; median age 2...
April 25, 2018: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29694356/impact-of-confinement-housing-on-study-end-points-in-the-calf-model-of-cryptosporidiosis
#13
Geneva Graef, Natalie J Hurst, Lance Kidder, Tracy L Sy, Laura B Goodman, Whitney D Preston, Samuel L M Arnold, Jennifer A Zambriski
BACKGROUND: Diarrhea is the second leading cause of death in children < 5 years globally and the parasite genus Cryptosporidium is a leading cause of that diarrhea. The global disease burden attributable to cryptosporidiosis is substantial and the only approved chemotherapeutic, nitazoxanide, has poor efficacy in HIV positive children. Chemotherapeutic development is dependent on the calf model of cryptosporidiosis, which is the best approximation of human disease. However, the model is not consistently applied across research studies...
April 25, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29679879/polygenic-risk-score-of-serpina6-serpina1-associates-with-diurnal-and-stress-induced-hpa-axis-activity-in-children
#14
Siddheshwar Utge, Katri Räikkönen, Eero Kajantie, Jari Lipsanen, Sture Andersson, Timo Strandberg, Rebecca M Reynolds, Johan G Eriksson, Jari Lahti
PURPOSE: Corticosteroid-binding globulin (CBG) transports glucocorticoids in blood. Variation in genes SERPINA6 encoding for CBG, SERPINA2 and SERPINA1 (serpin family A member 6, 2, and 1) have been shown to influence morning plasma cortisol and CBG in adults. However, association of this genetic variation with diurnal and stress-induced salivary cortisol remain unknown. This study aims to investigate the effect of genetic variation in SERPINA6/2/1 loci on diurnal and stress-induced salivary cortisol in children...
April 13, 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29677033/characterization-of-the-glucocorticoid-receptor-in-children-undergoing-cardiac-surgery
#15
Saul Flores, David S Cooper, Amy M Opoka, Ilias Iliopoulos, Sarah Pluckebaum, Matthew N Alder, Kelli A Krallman, Rashmi D Sahay, Lin Fei, Hector R Wong
OBJECTIVES: Postoperative administration of corticosteroids is common practice for managing catecholamine refractory low cardiac output syndrome. Since corticosteroid activity is dependent on the glucocorticoid receptor, we sought to characterize glucocorticoid receptor levels in children undergoing cardiac surgery and examined the association between glucocorticoid receptor levels and cardiovascular dysfunction. DESIGN: Prospective observational cohort study. SETTING: Large, tertiary pediatric cardiac center...
April 19, 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29673814/assessment-of-hair-cortisol-as-a-potential-biomarker-for-possible-adrenal-suppression-due-to-inhaled-corticosteroid-use-in-children-with-asthma-a-retrospective-observational-study
#16
Laura Smy, Kaitlyn Shaw, Ursula Amstutz, Michelle Staub, Shahnaz Chaudhry, Anne Smith, Bruce Carleton, Gideon Koren
BACKGROUND: Inhaled corticosteroids (ICS) are the recommended long-term control therapy for asthma in children. However, concern exists regarding potential adrenal suppression with chronic ICS use. Our pilot study reported that hair cortisol in children was 50% lower during ICS therapy than prior to therapy, suggestive of adrenal suppression. OBJECTIVE: To evaluate hair cortisol concentration (HCC) as a potential biomarker for possible adrenal suppression from ICS use in children with asthma...
April 16, 2018: Clinical Biochemistry
https://www.readbyqxmd.com/read/29667488/testing-the-theory-of-resilience-and-relational-load-trrl-in-families-with-type-i-diabetes
#17
Tamara Afifi, Douglas Granger, Anne Ersig, Eva Tsalikian, Ariana Shahnazi, Sharde Davis, Kathryn Harrison, Michelle Acevedo Callejas, Audrey Scranton
The theory of resilience and relational load was tested with 60 couples and their adolescent children (ages 11-18) with type I diabetes (T1D). The couples participated in a stress-inducing conversation task in their home, followed by a random assignment to a two-week intervention designed to increase their relationship maintenance. Before the intervention, stronger communal orientation predicted greater maintenance for husbands and wives, but maintenance only reduced T1D stress for wives. The wives' and adolescents' T1D stress were also correlated, but the husbands' T1D stress was not significantly associated with either of them...
April 18, 2018: Health Communication
https://www.readbyqxmd.com/read/29656328/human-colostrum-action-against-giardia-lamblia-infection-influenced-by-hormones-and-advanced-maternal-age
#18
Queli Lisiane Castro Pereira, Cristiane de Castro Pernet Hara, Rubian Trindade Silva Fernandes, Danny Laura Gomes Fagundes, Aline do Carmo França-Botelho, Maria Aparecida Gomes, Eduardo Luzía França, Adenilda Cristina Honorio-França
Children are more susceptible to Giardia lamblia infection. Cells and hormones contained in human colostrum have an immunoprotective action against giardiasis, but the effects of advanced maternal age on these components are poorly understood. This study analyzed the colostrum of older women to determine melatonin and cortisol levels besides the participation of these hormones on the functional activity of phagocytes against G. lamblia. Colostrum samples were collected from younger (18 to 35 years old) and older (over 36 years old) lactating women...
April 14, 2018: Parasitology Research
https://www.readbyqxmd.com/read/29652216/psychophysiological-measures-of-stress-in-caregivers-of-individuals-with-autism-spectrum-disorder-a-systematic-review
#19
Ciara Padden, Carolina Concialdi-McGlynn, Sinead Lydon
PURPOSE: Parents of children with autism spectrum disorder (ASD) often self-report heightened levels of stress and physical health problems. This paper reviewed studies assessing physiological measures of stress among parents of children with ASD. METHODS: Systematic database searches identified 15 studies meeting inclusion criteria. Studies were reviewed to determine: (a) control group characteristics; (b) caregiver and care recipient characteristics; (c) setting; (d) physiological measures employed; (e) physiological outcomes; and (f) stressor type...
April 13, 2018: Developmental Neurorehabilitation
https://www.readbyqxmd.com/read/29626707/longitudinal-association-between-psychosocial-stress-and-retinal-microvasculature-in-children-and-adolescents
#20
Carola J C Van Aart, Tim S Nawrot, Isabelle Sioen, Patrick De Boever, Mahmoud Zaqout, Stefaan De Henauw, Nathalie Michels
BACKGROUND: Retinal microvessels provides a window to assess the microcirculation of heart and brain, and might reflect cardio- or cerebrovascular disease risk. Limited information exist on the relation between psychosocial stress and the microcirculation, even though psychosocial stress might trigger vascular diseases. This study investigates whether childhood psychosocial stress is a predictor of retinal microvasculature. METHODS: We followed-up 182 Belgian children, aged 5...
March 30, 2018: Psychoneuroendocrinology
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