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Relational priming

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https://www.readbyqxmd.com/read/28231395/functional-connectivity-in-amygdalar-sensory-pre-motor-networks-at-rest-new-evidence-from-the-human-connectome-project
#1
Nicola Toschi, Andrea Duggento, Luca Passamonti
The word "e-motion" derives from the Latin word "ex-moveo" which literally means "moving away from something / somebody". Emotions are thus fundamental to prime action and goal-directed behavior with obvious implications for individual's survival. However, the brain mechanisms underlying the interactions between emotional and motor cortical systems remain poorly understood. A recent diffusion tensor imaging study in humans has reported the existence of direct anatomical connections between the amygdala and sensory/(pre)motor cortices, corroborating an initial observation in animal research...
February 23, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28231331/mesenchymal-stromal-cells-mscs-induce-ex-vivo-proliferation-and-erythroid-commitment-of-cord-blood-haematopoietic-stem-cells-cb-cd34-cells
#2
Simone Perucca, Andrea Di Palma, Pier Paolo Piccaluga, Claudia Gemelli, Elisa Zoratti, Giulio Bassi, Edoardo Giacopuzzi, Andrea Lojacono, Giuseppe Borsani, Enrico Tagliafico, Maria Teresa Scupoli, Simona Bernardi, Camilla Zanaglio, Federica Cattina, Valeria Cancelli, Michele Malagola, Mauro Krampera, Mirella Marini, Camillo Almici, Sergio Ferrari, Domenico Russo
A human bone marrow-derived mesenchymal stromal cell (MSCs) and cord blood-derived CD34+ stem cell co-culture system was set up in order to evaluate the proliferative and differentiative effects induced by MSCs on CD34+ stem cells, and the reciprocal influences on gene expression profiles. After 10 days of co-culture, non-adherent (SN-fraction) and adherent (AD-fraction) CD34+ stem cells were collected and analysed separately. In the presence of MSCs, a significant increase in CD34+ cell number was observed (fold increase = 14...
2017: PloS One
https://www.readbyqxmd.com/read/28229117/dna-methylation-data-for-identification-of-epigenetic-targets-of-resveratrol-in-triple-negative-breast-cancer-cells
#3
Rubiceli Medina-Aguilar, Carlos Pérez-Plasencia, Patricio Gariglio, Laurence A Marchat, Ali Flores-Pérez, César López-Camarillo, Jaime García Mena
Previous studies revealed that some bioactive food components have anti-cancer effects. However epigenetic effects of dietary compound resveratrol are largely unknown in breast cancer cells (M.A. Dawson, T. Kouzarides, 2012) [1]. Here we provide novel data and comparisons of DNA methylation status of promoter gene regions in response to resveratrol treatment at 24 h and 48 h versus untreated MDA-MB-231 breast cancer cells. DNA methylation changes were measured using Array-PRIMES method (aPRIMES) followed by whole-genome hybridization using human DNA methylation promoter microarray NimbleGen HG18 Refseq Promoter 3×720 K array...
April 2017: Data in Brief
https://www.readbyqxmd.com/read/28229068/the-characteristics-of-emotional-response-of-post-traumatic-stress-disorder-and-post-traumatic-growth-among-chinese-adults-exposed-to-an-explosion-incident
#4
Chuguang Wei, Jin Han, Yuqing Zhang, Walter Hannak, Zhengkui Liu
PURPOSE: Post-traumatic stress disorder (PTSD) and post-traumatic growth (PTG) are two different outcomes that may occur after experiencing traumatic events. Meanwhile, the traumatic exposure level and emotion response played an important role in the process. The present study first evaluated the relationship between PTSD, PTG, and traumatic exposure level and then compared the characteristics of emotional response through response time of the affective priming paradigm. METHODS: For the purpose of evaluating the relationship between PTSD, PTG, and trauma exposure level, a sample of 2,395 participants completed measures of posttraumatic stress disorder Checklist-Civilian Version (PCL-C), Post-traumatic Growth Inventory (PTGI) and a trauma exposure-related survey, and Pearson's correlation analysis for the scales were conducted...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28228053/hiv-related-pneumococcal-disease-prevention-in-adults
#5
Charles Feldman, Ronald Anderson, Theresa Rossouw
HIV-infected persons are particularly susceptible to the development of severe pneumococcal disease, even in the setting of combination antiretroviral therapy (cART), due to slow, incomplete recovery of anti-pneumococcal host defenses. This risk is increased by avoidable aspects of lifestyle, particularly smoking, which intensify immunosuppression. Clearly, more effective preventive measures are needed to counter this threat. Areas covered: This is a detailed review of the published literature focusing on currently available strategies for prevention of pneumococcal infection in HIV-infected patients, including cotrimoxazole prophylaxis, cART, pneumococcal vaccination, and smoking cessation strategies...
March 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/28227788/lessons-learnt-from-a-mooc-about-social-media-for-digital-health-literacy
#6
Suleman Atique, Mowafa Hosueh, Luis Fernandez-Luque, Elia Gabarron, Marian Wan, Onkar Singh, Vicente Traver Salcedo, Yu-Chuan Jack Li, Syed-Abdul Shabbir, Suleman Atique, Mowafa Hosueh, Luis Fernandez-Luque, Elia Gabarron, Marian Wan, Onkar Singh, Vicente Traver Salcedo, Yu-Chuan Jack Li, Syed-Abdul Shabbir, Elia Gabarron, Marian Wan, Mowafa Hosueh, Luis Fernandez-Luque, Onkar Singh, Syed-Abdul Shabbir, Yu-Chuan Jack Li, Vicente Traver Salcedo, Suleman Atique
Nowadays, the Internet and social media represent prime channels for health information seeking and peer support. However, benefits of health social media can be reduced by low digital health literacy. We designed a massive open online course (MOOC) course about health social media to increase the students' digital health literacy. In this course, we wanted to explore the difficulties confronted by the MOOC users in relation to accessing quality online health information and to propose methods to overcome the issues...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226194/melatonin-systemically-ameliorates-drought-stress-induced-damage-in-medicago-sativa-plants-by-modulating-nitro-oxidative-homeostasis-and-proline-metabolism
#7
Chrystalla Antoniou, Giannis Chatzimichail, Rafaella Xenofontos, Giannis Pavlou, Evangelia Panagiotou, Anastasis Christou, Vasileios Fotopoulos
Recent reports have uncovered the multifunctional role of melatonin in plant physiological responses under optimal and sub-optimal environmental conditions. In this study, we explored whether melatonin pretreatment could provoke priming effects in alfalfa (Medicago sativa L.) plants subsequently exposed to prolonged drought stress (7 days), by withholding watering. Results revealed that the rhizospheric application of melatonin (10 μM) remarkably enhanced the drought tolerance of alfalfa plants, as evidenced by the observed plant tolerant phenotype, as well as by the higher levels of chlorophyll fluorescence and stomatal conductance, compared with non-treated drought-stressed plants...
February 22, 2017: Journal of Pineal Research
https://www.readbyqxmd.com/read/28224704/advanced-glycation-end-products-regulate-anabolic-and-catabolic-activities-via-nlrp3-inflammasome-activation-in-human-nucleus-pulposus-cells
#8
Yu Song, Yan Wang, Yukun Zhang, Wen Geng, Wei Liu, Yong Gao, Shuai Li, Kun Wang, Xinghuo Wu, Liang Kang, Cao Yang
Intervertebral disc degeneration is widely recognized as a cause of lower back pain, neurological dysfunction and other musculoskeletal disorders. The major inflammatory cytokine IL-1β is associated with intervertebral disc degeneration; however, the molecular mechanisms that drive IL-1β production in the intervertebral disc, especially in nucleus pulposus (NP) cells, are unknown. In some tissues, advanced glycation end products (AGEs), which accumulate in NP tissues and promote its degeneration, increase oxidative stress and IL-1β secretion, resulting in disorders, such as obesity, diabetes mellitus and ageing...
February 22, 2017: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/28224480/print-exposure-modulates-the-effects-of-repetition-priming-during-sentence-reading
#9
Matthew W Lowder, Peter C Gordon
Individual readers vary greatly in the quality of their lexical representations, and consequently in how quickly and efficiently they can access orthographic and lexical knowledge. This variability may be explained, at least in part, by individual differences in exposure to printed language, because practice at reading promotes the development of stronger reading skills. In the present eyetracking experiment, we tested the hypothesis that the efficiency of word recognition during reading improves with increases in print exposure, by determining whether the magnitude of the repetition-priming effect is modulated by individual differences in scores on the author recognition test (ART)...
February 21, 2017: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/28219257/gestalt-effects-in-visual-working-memory
#10
Patrycja Kałamała, Aleksandra Sadowska, Wawrzyniec Ordziniak, Adam Chuderski
Four experiments investigated whether conforming to Gestalt principles, well known to drive visual perception, also facilitates the active maintenance of information in visual working memory (VWM). We used the change detection task, which required the memorization of visual patterns composed of several shapes. We observed no effects of symmetry of visual patterns on VWM performance. However, there was a moderate positive effect when a particular shape that was probed matched the shape of the whole pattern (the whole-part similarity effect)...
January 2017: Experimental Psychology
https://www.readbyqxmd.com/read/28218529/antibacterial-paramagnetic-quinones-from-actinoallomurus
#11
Marianna Iorio, João Cruz, Matteo Simone, Alice Bernasconi, Cristina Brunati, Margherita Sosio, Stefano Donadio, Sonia I Maffioli
Four metabolites, designated paramagnetoquinone A, B, C, and D (1-4), were isolated from three strains belonging to the actinomycete genus Actinoallomurus. Compounds 1 and 2 showed potent antibacterial activity with MIC values lower than 0.015 μg/mL against Gram-positive pathogens, including antibiotic-resistant strains. Since compounds 1 and 2 were NMR-silent due to the presence of an oxygen radical, structure elucidation was achieved through a combination of derivatizations, oxidations, and analysis of (13)C-labeled compounds...
February 20, 2017: Journal of Natural Products
https://www.readbyqxmd.com/read/28218439/the-effects-of-exogenous-fatty-acids-and-niacin-on-human-monocyte-macrophage-plasticity
#12
Sergio Montserrat-de la Paz, Dolores Rodriguez, Magdalena P Cardelo, Maria C Naranjo, Beatriz Bermudez, Rocio Abia, Francisco J G Muriana, Sergio Lopez
SCOPE: Macrophage plasticity allows adapting to different environments, having a dual activity in inflammatory-related diseases. Our hypothesis is that the type of dietary fatty acids into human postprandial triglyceride-rich lipoproteins (TRLs), alone or in combination with niacin (vitamin B3), could modulate the plasticity of monocytes-macrophages. METHODS AND RESULTS: We isolated TRLs at the postprandial peak from blood samples of healthy volunteers after the ingestion of a meal rich in saturated fatty acids (SFAs), monounsaturated fatty acids (MUFAs) or MUFAs plus omega-3 long-chain polyunsaturated fatty acids (LCPUFAs)...
February 20, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28217529/study-of-awareness-of-adrenal-disorders-among-interns-and-postgraduate-students-of-hamidia-hospital-bhopal
#13
Sachin Chittawar, T N Dubey, Jitendra Sharma, Sagar Khandare
INTRODUCTION: Adrenal disorders could be a life-threatening emergency, hence requires immediate therapeutic management. For this awareness regarding its diagnosis, management, and treatment is prime important. AIMS AND OBJECTIVE: To study the awareness of adrenal disorders among interns and postgraduates students of Hamidia Hospital, Bhopal. MATERIALS AND METHODS: A cross-sectional questionnaire-based study was performed. Fifty-six participants, i...
January 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28216948/averrhoa-bilimbi-linn-a-review-of-its-ethnomedicinal-uses-phytochemistry-and-pharmacology
#14
REVIEW
Alhassan Muhammad Alhassan, Qamar Uddin Ahmed
Averrhoa bilimbi Linn. is principally cultivated for medicinal purposes in many tropical and subtropical countries of the world. Literature survey about this plant shows that A. bilimbi is mainly used as a folk medicine in the treatment of diabetes mellitus, hypertension, and as an antimicrobial agent. The prime objective of this review is to accumulate and organize literature based on traditional claims and correlate those with current findings on the use of A. bilimbi in the management of different ailments...
October 2016: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28216902/feeble-antipyretic-analgesic-and-anti-inflammatory-activities-were-found-with-regular-dose-4-o-%C3%AE-d-glucosyl-5-o-methylvisamminol-one-of-the-conventional-marker-compounds-for-quality-evaluation-of-radix-saposhnikoviae
#15
Jing-Ming Yang, Hua Jiang, Hong-Liang Dai, Zi-Wei Wang, Gui-Zhi Jia, Xiang-Cai Meng
INTRODUCTION: 4'-O-β-D-glucosyl-5-O-methylvisamminol (GML) is a conventional marker compound for quality control of Radix Saposhnikoviae. Despite that, neither pharmacodynamic or pharmacokinetic information is available with regard to GML. As such, the aim of thisstudy was to assess the conventional evaluation indices for the quality of Radix Saposhnikoviae. MATERIALS AND METHODS: Pyretic animal model, hot plate test, and ear edema model were established to evaluate and compare the antipyretic, analgesic, and anti-inflammatory effect of the chromone derivativescimifugin, prime-O-glucosylcimifugin (PGCN), and GML in Radix Saposhnikoviae...
January 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28216234/optimal-modified-tracking-performance-for-mimo-networked-control-systems-with-communication-constraints
#16
Jie Wu, Zhu-Jun Zhou, Xi-Sheng Zhan, Huai-Cheng Yan, Ming-Feng Ge
This paper investigates the optimal modified tracking performance of multi-input multi-output (MIMO) networked control systems (NCSs) with packet dropouts and bandwidth constraints. Some explicit expressions are obtained by using co-prime factorization and the spectral decomposition technique. The obtained results show that the optimal modified tracking performance is related to the intrinsic properties of a given plant such as non-minimum phase (NMP) zeros, unstable poles, and their directions. Furthermore, the modified factor, packet dropouts probability and bandwidth also impact the optimal modified tracking performance of the NCSs...
February 16, 2017: ISA Transactions
https://www.readbyqxmd.com/read/28215227/elucidating-the-mutational-landscape-in-hepatocyte-nuclear-factor-1%C3%AE-hnf1b-by-computational-approach
#17
P Sneha, C G P Doss
Transcription factors are the major gene-regulatory proteins that recognize specific nucleotide sequences and bind to them. Missense mutations in transcription factors play a significant role in misregulation of gene expression contributing to various diseases and disorders. Understanding their structural and functional impact of the disease-causing mutations becomes prime importance in treating a disease. Commonly associated defect with the mutations of hepatocyte nuclear factor 1 beta (HNF1B) protein, a transcription factor results in maturity-onset diabetes of the young-5 (MODY-5) leading to loss of function...
2017: Advances in Protein Chemistry and Structural Biology
https://www.readbyqxmd.com/read/28213090/glycyrrhetinic-acid-attenuates-lipopolysaccharide-induced-fulminant-hepatic-failure-in-d-galactosamine-sensitized-mice-by-up-regulating-expression-of-interleukin-1-receptor-associated-kinase-m
#18
Xinru Yin, Xia Gong, Li Zhang, Rong Jiang, Ge Kuang, Bin Wang, Xinyu Chen, Jingyuan Wan
Glycyrrhetinic acid (GA), the main active ingredient of licorice, reportedly has anti-inflammatory and hepatoprotective properties, but its molecular mechanisms remain be elusive. In the present study, Balb/c mice were pretreated with GA (10, 30, or 100mg/kg) 1h before lipopolysaccharide (LPS)/d-galactosamine (D-GalN) administration. In other in vitro experiment, RAW264.7 macrophages were pretreated with GA before LPS exposure. The mortality, hepatic tissue histology, serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were analyzed...
February 14, 2017: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/28212614/transcriptomic-profiling-provides-molecular-insights-into-hydrogen-peroxide-induced-adventitious-rooting-in-mung-bean-seedlings
#19
Shi-Weng Li, Yan Leng, Rui-Fang Shi
BACKGROUND: Hydrogen peroxide (H2O2) has been known to function as a signalling molecule involved in the modulation of various physiological processes in plants. H2O2 has been shown to act as a promoter during adventitious root formation in hypocotyl cuttings. In this study, RNA-Seq was performed to reveal the molecular mechanisms underlying H2O2-induced adventitious rooting. RESULTS: RNA-Seq data revealed that H2O2 treatment greatly increased the numbers of clean reads and expressed genes and abundance of gene expression relative to the water treatment...
February 17, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28212428/a-novel-hemagglutinin-protein-produced-in-bacteria-protects-chickens-against-h5n1-highly-pathogenic-avian-influenza-viruses-by-inducing-h5-subtype-specific-neutralizing-antibodies
#20
Violetta Sączyńska, Agnieszka Romanik, Katarzyna Florys, Violetta Cecuda-Adamczewska, Małgorzata Kęsik-Brodacka, Krzysztof Śmietanka, Monika Olszewska, Katarzyna Domańska-Blicharz, Zenon Minta, Bogusław Szewczyk, Grażyna Płucienniczak, Andrzej Płucienniczak
The highly pathogenic (HP) H5N1 avian influenza viruses (AIVs) cause a mortality rate of up to 100% in infected chickens and pose a permanent pandemic threat. Attempts to obtain effective vaccines against H5N1 HPAIVs have focused on hemagglutinin (HA), an immunodominant viral antigen capable of eliciting neutralizing antibodies. The vast majority of vaccine projects have been performed using eukaryotic expression systems. In contrast, we used a bacterial expression system to produce vaccine HA protein (bacterial HA) according to our own design...
2017: PloS One
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