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https://www.readbyqxmd.com/read/28814791/molecular-dynamics-simulations-of-heterogeneous-cell-membranes-in-response-to-uniaxial-membrane-stretches-at-high-loading-rates
#1
Lili Zhang, Zesheng Zhang, John Jasa, Dongli Li, Robin O Cleveland, Mehrdad Negahban, Antoine Jérusalem
The chemobiomechanical signatures of diseased cells are often distinctively different from that of healthy cells. This mainly arises from cellular structural/compositional alterations induced by disease development or therapeutic molecules. Therapeutic shock waves have the potential to mechanically destroy diseased cells and/or increase cell membrane permeability for drug delivery. However, the biomolecular mechanisms by which shock waves interact with diseased and healthy cellular components remain largely unknown...
August 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28813416/large-turbulent-reservoirs-of-cold-molecular-gas-around-high-redshift-starburst-galaxies
#2
E Falgarone, M A Zwaan, B Godard, E Bergin, R J Ivison, P M Andreani, F Bournaud, R S Bussmann, D Elbaz, A Omont, I Oteo, F Walter
Starburst galaxies at the peak of cosmic star formation are among the most extreme star-forming engines in the Universe, producing stars over about 100 million years (ref. 2). The star-formation rates of these galaxies, which exceed 100 solar masses per year, require large reservoirs of cold molecular gas to be delivered to their cores, despite strong feedback from stars or active galactic nuclei. Consequently, starburst galaxies are ideal for studying the interplay between this feedback and the growth of a galaxy...
August 14, 2017: Nature
https://www.readbyqxmd.com/read/28809681/a-prototype-therapy-system-for-transcutaneous-application-of-boiling-histotripsy
#3
Adam D Maxwell, Petr V Yuldashev, Wayne Kreider, Tatiana D Khokhlova, George R Schade, Timothy L Hall, Oleg A Sapozhnikov, Michael R Bailey, Vera A Khokhlova
Boiling histotripsy is a method of focused ultrasound surgery that noninvasively applies millisecond-length pulses with high-amplitude shock fronts to generate liquefied lesions in tissue. Such a technique requires unique outputs compared to a focused ultrasound thermal therapy apparatus, particularly to achieve high in situ pressure levels through intervening tissue. This article describes the design and characterization of a system capable of producing the necessary pressure to transcutaneously administer boiling histotripsy therapy through clinically relevant overlying tissue paths using pulses with duration up to 10 ms...
August 14, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28804874/high-frequency-jet-ventilation-for-motion-management-during-ablation-procedures-a-narrative-review
#4
REVIEW
K Galmén, P Harbut, J Freedman, J G Jakobsson
BACKGROUND: High frequency jet ventilation (HFJV) is a method of ventilation that has gained renewed interest over the recent years as it can reduce organ movement to near static conditions, thus enhancing surgical precision in minimal invasive procedures, for example, ablation procedures for atrial fibrillation and solid organ tumours. The aim of this review was to create a summary of the current evidence concerning the clinical use of HFJV for ablative procedures. METHOD: PubMed was searched for the key words high frequency ventilation and ablation January 1990-December 2016...
August 13, 2017: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/28802985/clinical-analysis-of-48-h-emergency-department-visit-post-outpatient-extracorporeal-shock-wave-lithotripsy-for-urolithiasis
#5
Chin-Heng Lu, Junne-Yih Kuo, Tzu-Ping Lin, Yi-Hsiu Huang, Hsiao-Jen Chung, William J S Huang, Howard H H Wu, Yen-Hwa Chang, Alex T L Lin, Kuang-Kuo Chen
BACKGROUND: Patients suffering from renal or ureteral stones can undergo significant discomfort, even when timely diagnosed and treated. The aim of this study was to assess the risk factors and safety of outpatient Extracorporeal Shock Wave Lithotripsy (ESWL) in the management of patients with renal or ureteral stones. METHODS: In this study, our cohort consisted of 844 outpatients who underwent outpatient ESWL treated between February 2012 and November 2014 at Taipei Veterans General Hospital...
August 9, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/28794595/prevalence-of-diabetes-mellitus-after-extra-corporeal-shock-wave-lithotripsy-in-15-years-follow-up
#6
Fahimeh Kazemi Rashed, Nader Rash Ahmadi, Ali Zolfaghari, Alireza Farshi, Mohsen Amjadi, Mahboobeh Gholipour
OBJECTIVE: To investigate the hypothesis that extracorporeal shock wave lithotripsy (ESWL) increases the risk of new onset diabetes mellitus (DM) or significant changes in fasting blood sugar (FBS). MATERIALS AND METHODS: A total number of 307 patients enrolled in this study. All of them had undergone ESWL for kidney stone from 1991 to 1994. In 2009, after 15-19 years, we invited patients to check their blood sugar. RESULTS: There were 307 patients, 19...
July 2017: Urology Annals
https://www.readbyqxmd.com/read/28793039/low-energy-shock-wave-preconditioning-reduces-renal-ischemic-reperfusion-injury-caused-by-renal-artery-occlusion
#7
Yuquan Xue, Zhibin Xu, Haiwen Chen, Weimin Gan, Tie Chong
Purpose: To evaluate whether low energy shock wave preconditioning could reduce renal ischemic reperfusion injury caused by renal artery occlusion. Methods: The right kidneys of 64 male Sprague Dawley rats were removed to establish an isolated kidney model. The rats were then divided into four treatment groups: Group 1 was the sham treatment group; Group 2, received only low-energy (12 kv, 1 Hz, 200 times) shock wave preconditioning; Group 3 received the same low-energy shock wave preconditioning as Group 2, and then the left renal artery was occluded for 45 minutes; and Group 4 had the left renal artery occluded for 45 minutes...
July 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/28792145/impact-of-pretreatment-hydronephrosis-on-the-success-rate-of-shock-wave-lithotripsy-in-patients-with-ureteral-stone
#8
Ki Don Chang, Joo Yong Lee, Sung Yoon Park, Dong Hyuk Kang, Hyung Ho Lee, Kang Su Cho
PURPOSE: To evaluate predictors of the success rate for one session of shock wave lithotripsy (SWL), focusing on the relationships between pretreatment hydronephrosis grade and one-session SWL success rates. MATERIALS AND METHODS: The medical records of 1824 consecutive patients who underwent an initial session of SWL for treatment of urinary stones between 2005 and 2013 were reviewed. After exclusion, 700 patients with a single, 4-20 mm diameter radiopaque calculus were included in the study...
September 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/28775080/nephrolithisis-in-a-newborn-a-rare-case-and-review-of-literature
#9
Kawaljit Singh, Ashok Kumar Sokhal, Satyanarayan Sankhwar, Bimalesh Purkait
Nephrolithiasis, although a common entity in adults, is less common in children and rare in newborns. The evaluation and management strategies of renal stones in neonates are unclear. We report a rare scenario of renal calculus in a newborn aged 3 days presenting with decreased urine output, fever and crying during micturition. Patient was thoroughly investigated and managed conservatively. Further follow-up showed increase in stone size with recurrent urinary tract infections, hence shock wave lithotripsy was performed to successfully break and clear the stone fragments...
August 3, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28772739/discrete-particle-method-for-simulating-hypervelocity-impact-phenomena
#10
Erkai Watson, Martin O Steinhauser
In this paper, we introduce a computational model for the simulation of hypervelocity impact (HVI) phenomena which is based on the Discrete Element Method (DEM). Our paper constitutes the first application of DEM to the modeling and simulating of impact events for velocities beyond 5 kms(-1). We present here the results of a systematic numerical study on HVI of solids. For modeling the solids, we use discrete spherical particles that interact with each other via potentials. In our numerical investigations we are particularly interested in the dynamics of material fragmentation upon impact...
April 2, 2017: Materials
https://www.readbyqxmd.com/read/28772620/a-study-of-polycrystalline-silicon-damage-features-based-on-nanosecond-pulse-laser-irradiation-with-different-wavelength-effects
#11
Jiangmin Xu, Chao Chen, Tengfei Zhang, Zhenchun Han
Based on PVDF (piezoelectric sensing techniques), this paper attempts to study the propagation law of shock waves in brittle materials during the process of three-wavelength laser irradiation of polysilicon, and discusses the formation mechanism of thermal shock failure. The experimental results show that the vapor pressure effect and the plasma pressure effect in the process of pulsed laser irradiation lead to the splashing of high temperature and high density melt. With the decrease of the laser wavelength, the laser breakdown threshold decreases and the shock wave is weakened...
March 3, 2017: Materials
https://www.readbyqxmd.com/read/28772433/properties-of-a-laser-shock-wave-in-al-cu-alloy-under-elevated-temperatures-a-molecular-dynamics-simulation-study
#12
Xiankai Meng, Jianzhong Zhou, Shu Huang, Chun Su, Jie Sheng
The laser shock wave (LSW) generated by the interaction between a laser and a material has been widely used in laser manufacturing, such as laser shock peening and laser shock forming. However, due to the high strain rate, the propagation of LSW in materials, especially LSW at elevated temperatures, is difficult to study through experimental methods. A molecular dynamics simulation was used in this study to investigate the propagation of LSW in an Al-Cu alloy. The Hugoniot relations of LSW were obtained at different temperatures and the effects of elevated temperatures on shock velocity and shock pressure were analyzed...
January 18, 2017: Materials
https://www.readbyqxmd.com/read/28767169/urodynamic-and-molecular-characteristics-of-detrusor-underactivity-in-a-rat-cryoinjury-model-and-effects-of-low-energy-shock-wave-therapy
#13
Yao-Chi Chuang, Pradeep Tyagi, Hung-Jen Wang, Chao-Cheng Huang, Chih-Chieh Lin, Michael B Chancellor
AIMS: Low energy shock wave (LESW) has been shown to facilitate tissue regeneration and reduce inflammation. We investigated the effects of LESW in an underactive (DU) model induced by cryoinjury of rat detrusor. METHODS: Forty-six female Sprague-Dawley rats were divided into sham, cryoinjury with or without LESW (0.12 mJ/mm(2) ; 200 pulses). Under halothane anesthesia, a low midline incision was made and a cryoinjury of detrusor was induced by placing an aluminum rod (chilled with dry ice) for 30 s on the serosal side of the bladder filled with 1 mL sterile saline bilaterally...
August 2, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28766005/-what-is-the-current-status-of-shock-wave-lithotripsy
#14
REVIEW
A Neisius
BACKGROUND: Shock wave lithotripsy (SWL) became the therapy of choice for the majority of patients with urolithiasis early after its introduction in the early 1980s. Since then, SWL remains the only noninvasive therapy modality for the treatment of urinary stones. Although lithotripters became more versatile and affordable-making them available worldwide-indications for SWL have shifted as well. In most western countries, endoscopic techniques took the lead in stone therapy due to high (early) stone-free and better reimbursement rates...
August 1, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28764270/feasibility-and-complications-of-spinal-anaesthesia-in-percutaneous-nephrolithotomy-our-experience
#15
Manoj Kamal, Pradeep Sharma, Geeta Singariya, Rajesh Jain
INTRODUCTION: Percutaneous Nephrolithotomy (PCNL) is the treatment modality used for the extraction of large renal stones, or multiple calculi or stones resistant to shock wave lithotripsy. The General Anaesthesia (GA) is the standard modality for PCNL. However, few studies conclude that Spinal Anaesthesia (SA) can be an alternative method of anaesthesia with similar incidence of complications. AIM: In our study we evaluated the feasibility of spinal anaesthesia in terms of intraoperative and postoperative results in patients undergoing PCNL...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28764245/bilateral-staghorn-calculus-with-forgotten-double-j-stent-in-ileal-conduit-patient-a-rare-urological-challenge
#16
Rupesh Gupta, Ranjan Kumar Dey, Rakesh Sharma, Sweta Gupta
Forgotten DJ stent associated stone formation is not an uncommon entity. Here we are reporting the uncommon case of bilateral staghorn calculus due to forgotten DJ stent who had undergone radical cystectomy with ileal conduit diversion six years back. Management of these cases is a challenging urological situation due to inaccessible ureteric orifices. Patient was successfully treated with minimally invasive therapy in the form of combined bilateral PCNL (Percutaneous Nephrolithotomy) and ESWL (Extracorporeal Shock Wave Lithotripsy) therapy...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28763567/low-intensity-extracorporeal-shock-wave-therapy-promotes-myogenesis-through-perk-atf4-pathway
#17
Bohan Wang, Jun Zhou, Lia Banie, Amanda B Reed-Maldonado, Hongxiu Ning, Zhihua Lu, Yajun Ruan, Tie Zhou, Hsun Shuan Wang, Byung Seok Oh, Guifang Wang, Stanley Lei Qi, Guiting Lin, Tom F Lue
AIM: Stress urinary incontinence (SUI) is a significant health problem for women. Treatments employing muscle derived stem cells (MDSCs) may be a promising approach to this prevalent, bothersome condition, but these treatments are invasive and require collection of cells from one site for injection into another. It is also unknown whether or not these cells establish themselves and function as muscle cells in the target tissues. Alternatively, low-intensity extracorporeal shock wave therapy (Li-ESWT) is non-invasive and has shown positive outcomes in the treatment of multiple musculoskeletal disorders, but the biological effects responsible for clinical success are not yet well understood...
August 1, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28762588/an-investigation-of-shock-wave-therapy-and-low-intensity-pulsed-ultrasound-on-fracture-healing-under-reduced-loading-conditions-in-an-ovine-model
#18
Benjamin C Gadomski, Kirk C McGilvray, Jeremiah T Easley, Ross H Palmer, Jian Jiao, Xiaofei Li, Yi-Xian Qin, Christian M Puttlitz
The use of shock wave therapy (SWT) and low-intensity pulsed ultrasound (LIPUS) as countermeasures to the inhibited fracture healing experienced during mechanical unloading was investigated by administering treatment to the fracture sites of mature, female, Rambouillet Columbian ewes exposed to partial mechanical unloading or full gravitational loading. The amount of fracture healing experienced by the treatment groups was compared to controls in which identical surgical and testing protocols were administered except for SWT or LIPUS treatment...
August 1, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28759703/extracorporeal-shock-wave-treatment-can-selectively-destroy-endplates-in-neuromuscular-junctions
#19
Tomonori Kenmoku, Noriko Nemoto, Nahoko Iwakura, Nobuyasu Ochiai, Kentaro Uchida, Takashi Saisu, Seiji Ohtori, Koichi Nakagawa, Takahisa Sasho, Masashi Takaso
INTRODUCTION: This study assessed the effect of radial extracorporeal shock wave (rESW) exposure on neuromuscular transmission and neuromuscular junction (NMJ) morphology. METHODS: We applied 2,000 rESWs at 0.18 mJ/mm(2) and a frequency of 15 Hz to the right calf of male rats, measured the compound muscle action potential (CMAP) and examined NMJ morphology using electron microscopy. Left calf muscles were used as controls. RESULTS: rESW exposure significantly reduced CMAP amplitude without delayed latency in exposed muscles compared to controls...
July 31, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28759136/extracorporeal-shock-wave-therapy-for-chronic-wounds-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#20
Li Zhang, Changshui Weng, Zhanbo Zhao, Xiaobing Fu
A growing number of clinical studies demonstrate that extracorporeal shock wave therapy is a feasible noninvasive method for improving chronic wound healing. This systematic review and meta-analysis aimed to assess the effectiveness of extracorporeal shock wave therapy compared with that of the standard care treatment for the healing of chronic wounds, irrespective of etiology, in clinical practice. Randomized controlled trials that investigated the effect of extracorporeal shock wave therapy on chronic wounds with different etiologies from 2000 to 2017 were included in this review...
July 31, 2017: Wound Repair and Regeneration
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