keyword
MENU ▼
Read by QxMD icon Read
search

Colon cancer epidemiology

keyword
https://www.readbyqxmd.com/read/29115542/imp3-overexpression-occurs-in-various-important-cancer-types-and-is-linked-to-aggressive-tumor-features-a-tissue-microarray-study-on-8-877-human-cancers-and-normal-tissues
#1
Christoph Burdelski, Nilofar Jakani-Karimi, Frank Jacobsen, Christina Möller-Koop, Sarah Minner, Ronald Simon, Guido Sauter, Stefan Steurer, Till S Clauditz, Waldemar Wilczak
IMP3 is an RNA binding protein required for ribosomal RNA processing, which has been suggested to be a prognostic marker in a large variety of human types of cancer. However, available data on the prevalence of IMP3 expression are largely discrepant. To systematically investigate the epidemiology and clinical relevance of IMP3 expression in human cancers we employed a two-step tissue microarrays (TMAs) approach. First, a normal tissue TMA and a multi-tumor TMA were analyzed for immunohistochemically detectable expression of IMP3 in 76 different normal tissue types and 3889 cancer samples from 95 different tumor categories...
November 2, 2017: Oncology Reports
https://www.readbyqxmd.com/read/29055286/in-defense-of-progesterone-a-review-of-the-literature
#2
Allan Lieberman, Luke Curtis
Context • The medical literature on the use of progesterone in postmenopausal women is often confusing and contradictory. Some physicians implicate natural progesterone in an increase in the risk of breast cancer. The chemical structure of natural progesterone (P4) is quite different from chemically altered, synthetic chemicals called progestins, which results in different actions at the cell level. Objective • The research team intended to review the literature to examine the benefits and safety of natural progesterone and determine whether it can cause an increase or decrease in breast cancer risk...
October 21, 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/29049220/the-association-between-ccnd1-g870a-polymorphism-and-colorectal-cancer-risk-a-meta-analysis
#3
REVIEW
Mei Xie, Fen Zhao, Xiaoling Zou, Shuai Jin, Shaoquan Xiong
BACKGROUND: CyclinD1 (CCND1) is a key cell cycle regulatory protein. A large number of epidemiological studies have assessed the potential correlation between the CCND1 G870A polymorphism and the risk of colorectal cancer (CRC), but their findings have been inconsistent. To obtain a more precise understanding of the association between the G870A polymorphism in the CCND1 gene and the CRC risk, we conducted a more comprehensive meta-analysis. METHODOLOGY: We searched PubMed, Ovid, Springer, Weipu, China National Knowledge Infrastructure (CNKI), and Wanfang databases, covering all publications (the last search was updated on January 10, 2017)...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29039305/changing-epidemiology-of-pneumocystis-pneumonia-northern-ireland-uk-and-implications-for-prevention-1-july-2011-31-july-2012
#4
Lynsey Patterson, Peter Coyle, Tanya Curran, Neville Q Verlander, Jillian Johnston
PURPOSE: There is a lack of consensus about which non-human immunodeficiency virus (HIV) patient groups would benefit from prophylaxis. Here, we analysed an enhanced Pneumocystis jirovecii database to describe the epidemiology of Pneumocystis pneumonia (PCP) and P. jirovecii colonizations in Northern Ireland (NI) with a view to identifying risk groups who may benefit from prophylaxis. METHODOLOGY: We prospectively collected information on demographics, clinical severity and clinical features for all hospital inpatients in NI aged ≥18 years with P...
October 17, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29038151/obesity-and-cancer-evidence-impact-and-future-directions
#5
REVIEW
Graham A Colditz, Lindsay L Peterson
BACKGROUND: Mounting evidence, particularly from prospective epidemiologic studies but with additional support from animal models and mechanistic studies, supported conclusions in 2016 by the International Agency for Research on Cancer (IARC)(3) in their review of the preventive effects of weight control on cancer risk. CONTENT: The workgroup concluded that obesity is causally related to cancer at 13 anatomic sites (esophagus: adenocarcinoma; gastric cardia; colon and rectum; liver; gallbladder; pancreas; breast: postmenopausal; uterine endometrial; ovary; kidney: renal cell; meningioma; thyroid; and multiple myeloma)...
October 16, 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/29033760/colonic-ganglioneuroma-a-rare-finding-during-colorectal-cancer-screening
#6
Emmanuel Ofori, Mel Ona, Daryl Ramai, Tiangui Huang, Philip Xiao, Madhavi Reddy
Ganglioneuromas are very rare clinical entities, and their occurrence in the large bowel lays further emphasis on their rarity. Ganglioneuromas are benign tumors of undifferentiated neural crest cells. Their clinical presentation is mostly asymptomatic, and if any symptoms are present at all, they are usually nonspecific, with excellent prognosis. We report an asymptomatic, 65-year-old male with a solitary ascending colonic polyp found on screening colonoscopy. Histology revealed benign polypoid spindle-cell proliferation as well as S100 reactivity, consistent with ganglioneuroma...
May 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/29033218/early-onset-colorectal-cancer-is-distinct-from-traditional-colorectal-cancer
#7
Heather Yeo, Doron Betel, Jonathan S Abelson, Xi E Zheng, Rhonda Yantiss, Manish A Shah
BACKGROUND: Early-onset colorectal cancer (E-CRC) is increasing in incidence, unlike traditional CRC (T-CRC). We sought to characterize differences between E-CRC and T-CRC. MATERIALS AND METHODS: Data sources included the Surveillance, Epidemiology, and End Results database, the Behavioral Risk Factor Surveillance Survey, and The Cancer Genome Atlas (TCGA). We compared demographics, tumor characteristics, and incidence of CRC in subjects aged 20 to 49 years (E-CRC) with those aged ≥ 50 years (T-CRC)...
June 23, 2017: Clinical Colorectal Cancer
https://www.readbyqxmd.com/read/29025130/domain-specific-physical-activity-and-sedentary-behaviour-in-relation-to-colon-and-rectal-cancer-risk-a-systematic-review-and-meta-analysis
#8
Shahid Mahmood, Robert J MacInnis, Dallas R English, Amalia Karahalios, Brigid M Lynch
Background: Physical activity is associated with reduced risk of colorectal cancer, but most epidemiological studies have focused on occupational and recreational physical activity. The evidence for other domains of activity, and for sedentary behaviour, is limited. Methods: Medline, Embase and Web of Science were searched from inception to December 2015 for studies examining domain-specific physical activity or sedentary behaviour and the risk of colon and/or rectal cancer...
August 25, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29025095/the-mediterranean-diet-and-risk-of-colorectal-cancer-in-the-uk-women-s-cohort-study
#9
Petra Jones, Janet E Cade, Charlotte E L Evans, Neil Hancock, Darren C Greenwood
Background: Evidence from epidemiological studies investigating associations between adherence to the Mediterranean diet and colorectal cancer is inconsistent. The aim of this study is to assess in the UK Women's Cohort Study whether adherence to the Mediterranean dietary pattern is associated with reduced incidence of cancers of the colon and rectum. Method: A total of 35 372 women were followed for a median of 17.4 years. A 10-component score indicating adherence to the Mediterranean diet was generated for each cohort participant, using a 217-item food frequency questionnaire...
August 19, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29019575/colon-cancer-surgery-in-patients-operated-on-an-emergency-basis
#10
Rodrigo Felippe Ramos, Lucas Carvalho Santos Dos-Reis, Beatriz Esteves Borgeth Teixeira, Igor Maroso Andrade, Jaqueline Suelen Sulzbach, Ricardo Ary Leal
OBJECTIVE: to study the epidemiological profile of patients with colorectal cancer operated on an emergency basis at the Bonsucesso Federal Hospital. METHODS: this is a retrospective study of patients operated between January 1999 and December 2012. We analyzed the following variables: age, gender, clinical data, TMN staging, tumor location, survival and types of surgery. RESULTS: we evaluated 130 patients in the study period. The most frequent clinical picture was intestinal obstruction, in 78% of cases...
September 2017: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/29019328/second-primary-tumors-associated-with-breast-cancer-kuwait-cancer-control-center-experience
#11
Salah Fayaz, Gerges Attia Demian, Heba El-Sayed Eissa, Sadeq Abuzalouf
OBJECTIVES: To review the clinico-epidemiologic characteristics of patients who presented with two or more primary cancers, one of which was breast cancer (BC) and to develop a follow-up program for the high risk patients. PATIENTS AND METHODS: Patients who were diagnosed with BC and one or more non breast cancer (NBC) were retrospectively reviewed. Medical files were retrieved and epidemiological as well as clinical data were analyzed. RESULTS: Sixty-two patients were retrieved...
September 2017: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/28987338/increasing-colorectal-cancer-incidence-trends-among-younger-adults-in-canada
#12
Darren R Brenner, Yibing Ruan, Eileen Shaw, Prithwish De, Steven J Heitman, Robert J Hilsden
Recent analyses in the United States have shown an overall decrease in the incidence of colorectal cancer despite contrasting increases in younger age groups. We examined whether these cohort trends are occurring in Canada. Age-specific trends in colon and rectal cancer incidence in Canada from the National Cancer Incidence Reporting System (1969-1992) and the Canadian Cancer Registry (1992-2012) were analyzed. We estimated annual percent changes (APC) with the Joinpoint Regression Program from the Surveillance Epidemiology, and End Results Program...
December 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28978563/potential-medication-related-problems-in-older-breast-colon-and-lung-cancer-patients-in-the-united-states
#13
Jennifer L Lund, Hanna K Sanoff, Sharon Peacock-Hinton, Hyman Muss, Virginia Pate, Til Stürmer
BACKGROUND: Older adults are often exposed to multiple medications, some of which could be inappropriate or have the potential to interact with each other. Older cancer patients may be at increased risk for medication-related problems due to exposure to cancer-directed treatment. METHODS: We described patterns of potentially inappropriate medication (PIM) use and potential drug-chemotherapy interactions among adults age 66+ years diagnosed with stage I-III breast, stage II-III colon, and stage I-II lung cancer...
October 4, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28971436/long-term-survival-of-women-with-breast-cancer-overview-supportive-care-needs-assessment-instruments
#14
Parthenopi Ktistaki, Nephely Alevra, Maria Voulgari
INTRODUCTION: Worldwide, breast cancer is the fifth leading cause of cancer death (after lung, stomach, liver and colon cancer), while among women it is first on the list. The incidence of breast cancer has made a dramatic increase since 1970 which is partly interpreted by the modern western life standards. The expected risk of breast cancer throughout a lifespan of an average is 1 in 11 women. The five-year survival rates for breast cancer are at 80% if it has not spread, and only at 40% for the metastatic type of cancer...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28969691/pregnancy-associated-cancer-in-the-french-west-indies-martinique-maternal-and-neonatal-outcomes
#15
Kathleen Melan, Jean-Luc Volumenie, Gaël Wan-Ajouhu, Stephen Ulric-Gervaise, Jacqueline Veronique-Baudin, Clarisse Joachim
BACKGROUND: The management of pregnancy-associated-cancer (PAC) requires epidemiological evaluation of the pathways of care. The aim of this study was to describe maternal and neonatal outcomes of PAC in Martinique. METHODS: A retrospective study was conducted using data from medical records and the Martinique Cancer Registry for all PAC diagnosed between 1st January 2000 and 31st December 2014. RESULTS: Eighteen women were diagnosed with PAC: 17 during pregnancy and one during the postpartum period...
October 2, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28957966/management-of-colorectal-cancer-patients-undergoing-a-colonic-stenting-a-multidisciplinary-team-approach
#16
Bejo Utomo, Carmen Alvarez, Ricardo F Baldonedo
Colonic stent procedure is one of the best therapeutic medical interventions for managing a colorectal cancer patient with large bowel obstruction. This is a retrospective study that evaluated data from the past 10 years; it examined the epidemiological and clinical data of patients with colorectal cancer undergoing a colonic stent procedure. In addition, this study prospectively evaluated the nurse's roles during a colonic stent procedure, and at the same time, it explored the patient's satisfaction with the procedure at the Hospital Universitario Central de Asturias (Spain)...
September 2017: Gastroenterology Nursing: the Official Journal of the Society of Gastroenterology Nurses and Associates
https://www.readbyqxmd.com/read/28939585/mediating-effect-of-postsurgical-chemotherapy-on-presence-of-dementia-and-survival-among-patients-65-and-older-with-stage-iii-colon-cancer
#17
Yingjia Chen, Rosemary D Cress, Susan L Stewart, Thomas J Semrad, Danielle Harvey, Daniel J Tencredi, Laurel Beckett
Introduction: Both colon cancer and dementia are prevalent among the elderly and have a high risk of cooccurrence. Previous studies found that patients with dementia were treated less aggressively. In this study, we hypothesized that presence of preexisting dementia was associated with worse survival for stage III colon cancer patients, and that postoperative chemotherapy was on the causal pathway.Methods: We defined preexisting dementia in Surveillance Epidemiology and End Results Medicare data through either a formal diagnosis or a prescription for dementia drugs or both before the diagnosis of cancer...
September 22, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28927314/survivability-prediction-of-colon-cancer-patients-using-neural-networks
#18
Reda Al-Bahrani, Ankit Agrawal, Alok Choudhary
We utilize deep neural networks to develop prediction models for patient survival and conditional survival of colon cancer. Our models are trained and validated on data obtained from the Surveillance, Epidemiology, and End Results Program. We provide an online outcome calculator for 1, 2, and 5 years survival periods. We experimented with multiple neural network structures and found that a network with five hidden layers produces the best results for these data. Moreover, the online outcome calculator provides conditional survival of 1, 2, and 5 years after surviving the mentioned survival periods...
September 1, 2017: Health Informatics Journal
https://www.readbyqxmd.com/read/28927103/lack-of-chemopreventive-efficacy-of-metformin-in-rodent-models-of-urinary-bladder-head-and-neck-and-colon-intestine-cancer
#19
Matthew D Thompson, Ronald A Lubet, David L Mccormick, Margie L Clapper, Ann M Bode, M Margaret Juliana, Fariba Moeinpour, Clinton J Grubbs
Metformin is a biguanide employed in treating type II diabetes. Its potential efficacy for treating cancer has been demonstrated epidemiologically (lower cancer incidence in metformin users compared with users of sulfonylureas or insulin) and mechanistically, primarily in cell culture. Metformin decreases the levels of insulin-like growth factor 1 and secondarily inhibits the mammalian target of rapamycin pathway to exhibit anticancer effects. The current study examined its cancer preventive efficacy in multiple standard in situ arising cancer models...
September 2017: Oncology Letters
https://www.readbyqxmd.com/read/28881631/comparison-of-long-term-outcome-between-hemicolectomy-and-partial-colectomy-in-the-elderly-a-large-population-based-study
#20
Xu Guan, Hanqing Hu, Wei Chen, Zheng Jiang, Zheng Liu, Zhixun Zhao, Yinggang Chen, Guiyu Wang, Xishan Wang
Due to large progress has been achieved in surgical techniques, anesthesia and perioperative care, it is accepted that the very elderly colon cancer (CC) patient is not contraindication for surgery. However, it is a controversy that an extended or a less aggressive surgical approach should be performed for this population. Here, we identified 28110 CC patients aged ≥80 from Surveillance, Epidemiology, and End-Results (SEER) database. The surgical approaches included extended hemicolectomy (HC) and partial colectomy (PC)...
August 1, 2017: Oncotarget
keyword
keyword
57141
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"