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https://www.readbyqxmd.com/read/27879305/partial-segmental-thrombosis-of-the-corpus-cavernosum-presenting-with-perineal-pain
#1
Michelle Christodoulidou, Arie Parnham, Navin Ramachandran, Asif Muneer
We describe the case of a man aged 43 years who presented with a 2-week history of a palpable lump in the right proximal penile shaft. This was preceded by a 6-month history of perineal pain, accompanied by erectile dysfunction. An urgent MRI scan of his penis identified a thrombus within the right crus and corpus of the penis. His thrombophilia screen was normal. The patient was started on oral anticoagulation and a phosphodiesterase inhibitor (PDE-5i) to prevent thrombus progression and maintain erectile function...
November 22, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27871962/penile-implant-review-of-a-no-touch-technique
#2
REVIEW
J Francois Eid
INTRODUCTION: Over 25% of the more than 725,000 cases of nosocomial infection in the United States are related to an implantable device. Despite the standard typical strategies available, infection rates for breast implants, cerebrospinal shunts, and penile implants remain unacceptably high. This paper will review use of a "no-touch" technique in varied surgical procedures from orthopedic fracture repair, cerebrospinal fluid shunt placement, and breast reconstruction/augmentation to penile prosthesis implantation...
July 2016: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/27855594/when-chems-meet-sex-a-rising-phenomenon-called-chemsex
#3
Raffaele Giorgetti, Adriano Tagliabracci, Fabrizio Schifano, Simona Zaami, Enrico Marinelli, Francesco Paolo Busardò
BACKGROUND: The term "chemsex" was coined to indicate the voluntary intake of psychoactive and non psychoactive drugs in the context of recreational settings to facilitate and/or to enhance sexual intercourses mostly among men who have sex with other men (MSM). OBJECTIVE: The authors aimed to review the mechanisms of action, the toxicity and the pattern of use and abuse of substances involved in "chemsex" practice together with the sociocultural background underlying it and the health-related consequences that they may have...
November 17, 2016: Current Neuropharmacology
https://www.readbyqxmd.com/read/27822104/the-danish-national-penile-cancer-quality-database
#4
REVIEW
Jakob Kristian Jakobsen, Buket Öztürk, Mette Søgaard
AIM OF DATABASE: The Danish National Penile Cancer Quality database (DaPeCa-data) aims to improve the quality of cancer care and monitor the diagnosis, staging, and treatment of all incident penile cancer cases in Denmark. The aim is to assure referral practice, guideline adherence, and treatment and development of the database in order to enhance research opportunities and increase knowledge and survival outcomes of penile cancer. STUDY POPULATION: The DaPeCa-data registers all patients with newly diagnosed invasive squamous cell carcinoma of the penis in Denmark since June 2011...
2016: Clinical Epidemiology
https://www.readbyqxmd.com/read/27689159/investigation-of-penile-conditions-by-ultrasound-and-contrast-enhanced-ultrasound-presentation-of-three-clinical-cases
#5
J F Topsøe, D Dencker
No abstract text is available yet for this article.
November 2015: Ultrasound International Open
https://www.readbyqxmd.com/read/27650039/propping-up-pharma-s-natural-neoliberal-phallic-man-pharmaceutical-representations-of-the-ideal-sexuopharmaceutical-user
#6
Maria Gurevich, Usra Leedham, Amy Brown-Bowers, Nicole Cormier, Zara Mercer
Contemporary social theorists emphasise the cultural quest for authenticity under conditions of increasing artificiality. Within this context, the body is commonly treated as an 'unfinished' surface requiring ongoing transformation to fulfil identity obligations. In this paper, we examine one such identity authentication project in the form of marketing of men's sexuopharmaceuticals. We use online pharmaceutical advertising for four approved sexuopharmaceuticals (Viagra, Cialis, STAXYN and Stendra) to describe the ideal neoliberal consumer...
September 21, 2016: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/27624510/phosphodiesterase-5-inhibitor-use-an-under-reported-cause-of%C3%A2-profuse-nasal-bleeding
#7
Petros V Vlastarakos, Thomas P Nikolopoulos
BACKGROUND: Phosphodiesterase-5 (PDE-5) inhibitors enhance penile erection and have gained popularity not only for erectile dysfunction, but also in recreational settings. Nevertheless, adverse effects have been associated with their use, with nasal bleeding among them. PDE-5 inhibitor action is materialized through the inhibition of the cyclic guanosine monophosphate (cGMP) enzyme. cGMP is present at several sites of the human body in addition to the corpus cavernosum, leading to the adverse effects associated with its nonselective inhibition...
November 2016: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27593920/kelly-procedure-for-male-primary-epispadias
#8
Pankaj Mishra, Simon Rajendran, Maria Asimakidou, Imran Mushtaq
INTRODUCTION: Primary epispadias is a rare congenital malformation involving the urogenital system. In patients with epispadias, bladder closure enhances bladder growth and continence. METHODS: Several steps were carried out to bring the bladder neck to the midline and allow tension-free bladder neck reconstruction and recreation of the natural angulation of urethra. The urethral plate and penile shaft were dissected and the corpora cavernosa separated, and then the bladder neck repair was performed...
August 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/27557611/anti-inflammatory-and-anti-fibrotic-effects-of-annexin1-on-erectile-function-after-cavernous-nerve-injury-in-rats
#9
F N Facio, M F Facio, L F Spessoto, D Pessutti, L O Reis, S G Campos, S Taboga
The aim of this study was to investigate the effect of the anti-inflammatory and anti-fibrotic actions of ANX1 on erectile function (EF). Forty-eight male Wistar rats were randomly distributed into four equal groups: one group (sham operation-control) and three groups (bilateral cavernous nerve (CN) crush injury). Crush injury groups were treated prior to injury with an intravascular injection of either ANX1 (50 or 100 μg kg(-1)) or vehicle. EF was assessed by CN electrical stimulation at 2 and 7 days after CN injury with histomorphometric and immunohistochemical analysis...
August 25, 2016: International Journal of Impotence Research
https://www.readbyqxmd.com/read/27555512/response-and-rebuttal-to-editorial-comment-regarding-penile-girth-enhancement-with-pmma-based-soft-tissue-fillers
#10
Luis Casavantes, Gottfried Lemperle, Palmira Morales
No abstract text is available yet for this article.
September 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27555511/editorial-comment-on-penile-girth-enhancement-with-pmma-based-soft-tissue-fillers
#11
Gary J Alter
No abstract text is available yet for this article.
September 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27521839/hydrogen-sulfide-compensates-nitric-oxide-deficiency-in-murine-corpus-cavernosum
#12
Günay Yetik-Anacak, Aycan Dikmen, Ciro Coletta, Emma Mitidieri, Mehmet Dereli, Erminia Donnarumma, Roberta d'Emmanuele di Villa Bianca, Raffaella Sorrentino
Erectile dysfunction (ED) is considered as a marker for cardiovascular diseases. Nitric oxide (NO) deficiency is the major cause of erectile dysfunction (ED). The role of hydrogen sulfide (H2S) in erection has recently been recognized and is receiving attention as a pharmacological target. Several studies have focused on the effect of H2S on NO-dependent relaxation, but the role of NO on H2S in penile tissue has not been studied yet. Unlike NO, H2S is mainly synthesized from smooth muscle cells rather than endothelial cells...
August 10, 2016: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/27513384/higher-hpv16-and-hpv18-penile-viral-loads-are-associated-with-decreased-human-papillomavirus-clearance-in-uncircumcised-kenyan-men
#13
Virginia Senkomago, Danielle M Backes, Michael G Hudgens, Charles Poole, Steven R Meshnick, Kawango Agot, Stephen Moses, Peter Jf Snijders, Chris Jlm Meijer, Albertus T Hesselink, Nicolas F Schlecht, Robert C Bailey, Jennifer S Smith
BACKGROUND: Whether higher penile human papillomavirus (HPV) viral load is associated with a lower rate of HPV clearance remains unknown. OBJECTIVES: We examined the association between penile HPV16 and HPV18 viral load and subsequent HPV clearance in uncircumcised Kenyan men. STUDY DESIGN: Participants were human immunodeficiency virus (HIV)-seronegative, sexually active, 18- to 24-year-old men randomized to the control arm of a male circumcision trial in Kisumu, Kenya...
September 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27511302/geometrical-modified-nesbit-corporoplasty-to-correct-different-types-of-penile-curvature-description-of-the-surgical-procedure-based-on-geometrical-principles-and-long-term-results
#14
P Vicini, S Di Nicola, G Antonini, E De Berardinis, V Gentile, F De Marco
We present the use of a modified corporoplasty, based on geometrical principles, to determine the exact site for the incision in the tunica or plaque and the exact amount of albuginea for overlaying to correct with extreme precision the different types of congenital or acquired penile curvature due to Peyronie's disease. To describe our experience with a new surgical procedure for the enhancement of penile curvature avoiding any overcorrection or undercorrection. Between March 2004 and April 2013, a total of 74 patients underwent the geometrical modified corporoplasty...
August 11, 2016: International Journal of Impotence Research
https://www.readbyqxmd.com/read/27485215/10-year-experience-regarding-the-reliability-and-morbidity-of-radio-guided-lymph-node-biopsy-in-penile-cancer-patients-and-the-associated-radiation-exposure-of-medical-staff-in-this-procedure
#15
Ulf Lützen, Carsten Maik Naumann, Jens Dischinger, Marlies Marx, René Baumann, Yi Zhao, Michael Jüptner, Daniar Osmonov, Katrin Bothe, Klaus-Peter Jünemann, Maaz Zuhayra
BACKGROUND: The guidelines of the European Association of Urologists (EAU), of the German Society of Nuclear Medicine (DGN), and the European Society for Medical Oncology (ESMO) recommend sentinel lymph node biopsy (SLNB) for lymph node staging in penile cancer with non-palpable inguinal lymph nodes as one diagnostic method. Despite this, the method is neither widely nor regularly applied in Germany - the same applies to many other countries, which may be due to insecurity in dealing with open radioactive tracers...
2016: BMC Urology
https://www.readbyqxmd.com/read/27461963/penile-girth-enhancement-with-polymethylmethacrylate-based-soft-tissue-fillers
#16
Luis Casavantes, Gottfried Lemperle, Palmira Morales
INTRODUCTION: An unknown percentage of men will take every risk to develop a larger penis. Thus far, most injectables have caused serious problems. Polymethylmethacrylate (PMMA) microspheres have been injected as a wrinkle filler and volumizer with increasing safety since 1989. AIM: To report on a safe and permanently effective method to enhance penile girth and length with an approved dermal filler (ie, PMMA). METHODS: Since 2007, the senior author has performed penile augmentation in 752 men mainly with Metacrill, a suspension of PMMA microspheres in carboxymethyl-cellulose...
September 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27427555/combination-of-low-energy-shock-wave-therapy-and-bone-marrow-mesenchymal-stem-cell-transplantation-to-improve-the-erectile-function-of-diabetic-rats
#17
Hai-Tao Shan, Hai-Bo Zhang, Wen-Tao Chen, Feng-Zhi Chen, Tao Wang, Jin-Tai Luo, Min Yue, Ji-Hong Lin, An-Yang Wei
Stem cell transplantation and low-energy shock-wave therapy (LESWT) have emerged as potential and effective treatment protocols for diabetic erectile dysfunction. During the tracking of transplanted stem cells in diabetic erectile dysfunction models, the number of visible stem cells was rather low and decreased quickly. LESWT could recruit endogenous stem cells to the cavernous body and improve the microenvironment in diabetic cavernous tissue. Thus, we deduced that LESWT might benefit transplanted stem cell survival and improve the effects of stem cell transplantation...
July 12, 2016: Asian Journal of Andrology
https://www.readbyqxmd.com/read/27363331/checklist-assessment-tool-to-evaluate-suitability-and-success-of-neonatal-clamp-circumcision-a-prospective-study
#18
Charles W Concodora, Max Maizels, Gregory E Dean, Dana A Weiss, Seth A Alpert, John D Edmondson, Jack S Elder, Anthony Herndon, James M Elmore, Karen Rychlik
BACKGROUND: The American Academy of Pediatrics (AAP) Task Force on Circumcision has called for the development of standards of trainee proficiency in regards to evaluation and technique for neonatal clamp circumcision (NCC). At the present time, there is no standardized or general consensus on patient selection for NCC. An improved method to evaluate newborns for NCC is an important first step in this process. Therefore, the authors collaborated to identify criteria useful in the evaluation of newborns for suitability for NCC, and for assessment of success after NCC and have named it "Checklist Assessment for Neonatal Clamp Circumcision Suitability...
August 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/27283992/treatment-of-diabetes-mellitus-induced-erectile-dysfunction-using-endothelial-progenitor-cells-genetically-modified-with-human-telomerase-reverse-transcriptase
#19
Yan Zhang, Zhi Chen, Tao Wang, Jun Yang, Rui Li, Shaogang Wang, Jihong Liu, Zhangqun Ye
The efficacy of treatments for diabetes mellitus-induced erectile dysfunction (DMED) is quite poor, and stem cell therapy is emerging as a useful method. In this study, we used endothelial progenitor cells (EPCs) overexpressing human telomerase reverse transcriptase (hTERT) for the treatment of DMED. Rat EPCs were transfected with hTERT (EPCs-hTERT). EPCs-hTERT secreted more growth factors and demonstrated enhanced proliferation and resistance to oxidative stress. Twenty-four male DMED rats were subjected to four treatments: DMED (DMED group), EPCs (EPCs group), EPCs transduced with control lentivirus (EPC-control group) and EPCs-hTERT (EPCs-hTERT group)...
June 7, 2016: Oncotarget
https://www.readbyqxmd.com/read/27261182/urethral-foreign-bodies-clinical-presentation-and-management
#20
Cristina J Palmer, Matthew Houlihan, Sarah P Psutka, K Alexandria Ellis, Patricia Vidal, Courtney M P Hollowell
OBJECTIVE: To review a single institution's 15-year experience with urethral foreign bodies, including evaluation, clinical findings, and treatment. MATERIALS AND METHODS: In total, 27 patients comprising 35 episodes of inserted urethral foreign bodies were reviewed at Cook County Hospital between 2000 and 2015. Retrospective chart review was performed to describe the clinical presentation, rationale for insertion, management, recidivism, and sequelae. RESULTS: Median patient age was 26 (range 12-60)...
May 31, 2016: Urology
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