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penile enhancement

J F Topsøe, D Dencker
No abstract text is available yet for this article.
November 2015: Ultrasound Int Open
Maria Gurevich, Usra Leedham, Amy Brown-Bowers, Nicole Cormier, Zara Mercer
Contemporary social theorists emphasise the cultural quest for authenticity under conditions of increasing artificiality. Within this context, the body is commonly treated as an 'unfinished' surface requiring ongoing transformation to fulfil identity obligations. In this paper, we examine one such identity authentication project in the form of marketing of men's sexuopharmaceuticals. We use online pharmaceutical advertising for four approved sexuopharmaceuticals (Viagra, Cialis, STAXYN and Stendra) to describe the ideal neoliberal consumer...
September 21, 2016: Culture, Health & Sexuality
Petros V Vlastarakos, Thomas P Nikolopoulos
BACKGROUND: Phosphodiesterase-5 (PDE-5) inhibitors enhance penile erection and have gained popularity not only for erectile dysfunction, but also in recreational settings. Nevertheless, adverse effects have been associated with their use, with nasal bleeding among them. PDE-5 inhibitor action is materialized through the inhibition of the cyclic guanosine monophosphate (cGMP) enzyme. cGMP is present at several sites of the human body in addition to the corpus cavernosum, leading to the adverse effects associated with its nonselective inhibition...
September 10, 2016: Journal of Emergency Medicine
Pankaj Mishra, Simon Rajendran, Maria Asimakidou, Imran Mushtaq
INTRODUCTION: Primary epispadias is a rare congenital malformation involving the urogenital system. In patients with epispadias, bladder closure enhances bladder growth and continence. METHODS: Several steps were carried out to bring the bladder neck to the midline and allow tension-free bladder neck reconstruction and recreation of the natural angulation of urethra. The urethral plate and penile shaft were dissected and the corpora cavernosa separated, and then the bladder neck repair was performed...
August 2016: Journal of Pediatric Urology
F N Facio, M F Facio, L F Spessoto, D Pessutti, L O Reis, S G Campos, S Taboga
The aim of this study was to investigate the effect of the anti-inflammatory and anti-fibrotic actions of ANX1 on erectile function (EF). Forty-eight male Wistar rats were randomly distributed into four equal groups: one group (sham operation-control) and three groups (bilateral cavernous nerve (CN) crush injury). Crush injury groups were treated prior to injury with an intravascular injection of either ANX1 (50 or 100 μg kg(-1)) or vehicle. EF was assessed by CN electrical stimulation at 2 and 7 days after CN injury with histomorphometric and immunohistochemical analysis...
August 25, 2016: International Journal of Impotence Research
Luis Casavantes, Gottfried Lemperle, Palmira Morales
No abstract text is available yet for this article.
September 2016: Journal of Sexual Medicine
Gary J Alter
No abstract text is available yet for this article.
September 2016: Journal of Sexual Medicine
Günay Yetik-Anacak, Aycan Dikmen, Ciro Coletta, Emma Mitidieri, Mehmet Dereli, Erminia Donnarumma, Roberta d'Emmanuele di Villa Bianca, Raffaella Sorrentino
Erectile dysfunction (ED) is considered as a marker for cardiovascular diseases. Nitric oxide (NO) deficiency is the major cause of erectile dysfunction (ED). The role of hydrogen sulfide (H2S) in erection has recently been recognized and is receiving attention as a pharmacological target. Several studies have focused on the effect of H2S on NO-dependent relaxation, but the role of NO on H2S in penile tissue has not been studied yet. Unlike NO, H2S is mainly synthesized from smooth muscle cells rather than endothelial cells...
August 10, 2016: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
Virginia Senkomago, Danielle M Backes, Michael G Hudgens, Charles Poole, Steven R Meshnick, Kawango Agot, Stephen Moses, Peter Jf Snijders, Chris Jlm Meijer, Albertus T Hesselink, Nicolas F Schlecht, Robert C Bailey, Jennifer S Smith
BACKGROUND: Whether higher penile human papillomavirus (HPV) viral load is associated with a lower rate of HPV clearance remains unknown. OBJECTIVES: We examined the association between penile HPV16 and HPV18 viral load and subsequent HPV clearance in uncircumcised Kenyan men. STUDY DESIGN: Participants were human immunodeficiency virus (HIV)-seronegative, sexually active, 18- to 24-year-old men randomized to the control arm of a male circumcision trial in Kisumu, Kenya...
September 2016: Sexually Transmitted Diseases
P Vicini, S Di Nicola, G Antonini, E De Berardinis, V Gentile, F De Marco
We present the use of a modified corporoplasty, based on geometrical principles, to determine the exact site for the incision in the tunica or plaque and the exact amount of albuginea for overlaying to correct with extreme precision the different types of congenital or acquired penile curvature due to Peyronie's disease. To describe our experience with a new surgical procedure for the enhancement of penile curvature avoiding any overcorrection or undercorrection. Between March 2004 and April 2013, a total of 74 patients underwent the geometrical modified corporoplasty...
August 11, 2016: International Journal of Impotence Research
Ulf Lützen, Carsten Maik Naumann, Jens Dischinger, Marlies Marx, René Baumann, Yi Zhao, Michael Jüptner, Daniar Osmonov, Katrin Bothe, Klaus-Peter Jünemann, Maaz Zuhayra
BACKGROUND: The guidelines of the European Association of Urologists (EAU), of the German Society of Nuclear Medicine (DGN), and the European Society for Medical Oncology (ESMO) recommend sentinel lymph node biopsy (SLNB) for lymph node staging in penile cancer with non-palpable inguinal lymph nodes as one diagnostic method. Despite this, the method is neither widely nor regularly applied in Germany - the same applies to many other countries, which may be due to insecurity in dealing with open radioactive tracers...
2016: BMC Urology
Luis Casavantes, Gottfried Lemperle, Palmira Morales
INTRODUCTION: An unknown percentage of men will take every risk to develop a larger penis. Thus far, most injectables have caused serious problems. Polymethylmethacrylate (PMMA) microspheres have been injected as a wrinkle filler and volumizer with increasing safety since 1989. AIM: To report on a safe and permanently effective method to enhance penile girth and length with an approved dermal filler (ie, PMMA). METHODS: Since 2007, the senior author has performed penile augmentation in 752 men mainly with Metacrill, a suspension of PMMA microspheres in carboxymethyl-cellulose...
September 2016: Journal of Sexual Medicine
Hai-Tao Shan, Hai-Bo Zhang, Wen-Tao Chen, Feng-Zhi Chen, Tao Wang, Jin-Tai Luo, Min Yue, Ji-Hong Lin, An-Yang Wei
Stem cell transplantation and low-energy shock-wave therapy (LESWT) have emerged as potential and effective treatment protocols for diabetic erectile dysfunction. During the tracking of transplanted stem cells in diabetic erectile dysfunction models, the number of visible stem cells was rather low and decreased quickly. LESWT could recruit endogenous stem cells to the cavernous body and improve the microenvironment in diabetic cavernous tissue. Thus, we deduced that LESWT might benefit transplanted stem cell survival and improve the effects of stem cell transplantation...
July 12, 2016: Asian Journal of Andrology
Charles W Concodora, Max Maizels, Gregory E Dean, Dana A Weiss, Seth A Alpert, John D Edmondson, Jack S Elder, Anthony Herndon, James M Elmore, Karen Rychlik
BACKGROUND: The American Academy of Pediatrics (AAP) Task Force on Circumcision has called for the development of standards of trainee proficiency in regards to evaluation and technique for neonatal clamp circumcision (NCC). At the present time, there is no standardized or general consensus on patient selection for NCC. An improved method to evaluate newborns for NCC is an important first step in this process. Therefore, the authors collaborated to identify criteria useful in the evaluation of newborns for suitability for NCC, and for assessment of success after NCC and have named it "Checklist Assessment for Neonatal Clamp Circumcision Suitability...
August 2016: Journal of Pediatric Urology
Yan Zhang, Zhi Chen, Tao Wang, Jun Yang, Rui Li, Shaogang Wang, Jihong Liu, Zhangqun Ye
The efficacy of treatments for diabetes mellitus-induced erectile dysfunction (DMED) is quite poor, and stem cell therapy is emerging as a useful method. In this study, we used endothelial progenitor cells (EPCs) overexpressing human telomerase reverse transcriptase (hTERT) for the treatment of DMED. Rat EPCs were transfected with hTERT (EPCs-hTERT). EPCs-hTERT secreted more growth factors and demonstrated enhanced proliferation and resistance to oxidative stress. Twenty-four male DMED rats were subjected to four treatments: DMED (DMED group), EPCs (EPCs group), EPCs transduced with control lentivirus (EPC-control group) and EPCs-hTERT (EPCs-hTERT group)...
June 7, 2016: Oncotarget
Cristina J Palmer, Matthew Houlihan, Sarah P Psutka, K Alexandria Ellis, Patricia Vidal, Courtney M P Hollowell
OBJECTIVE: To review a single institution's 15-year experience with urethral foreign bodies, including evaluation, clinical findings, and treatment. MATERIALS AND METHODS: In total, 27 patients comprising 35 episodes of inserted urethral foreign bodies were reviewed at Cook County Hospital between 2000 and 2015. Retrospective chart review was performed to describe the clinical presentation, rationale for insertion, management, recidivism, and sequelae. RESULTS: Median patient age was 26 (range 12-60)...
May 31, 2016: Urology
Sheng Zhang, Wenfeng Li, Fei Liang
PurposeThis study investigated the value of Fluorine-18 2-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET)/computed tomography (CT) imaging in the management of patients with advanced penile cancer.Patients and MethodsBetween January 2009 and August 2012, 48 patients with penile cancer at our center underwent FDG-PET/CT after CT (n=39) or magnetic resonance imaging (MRI; n=9). The accuracy of FDG-PET/CT was assessed with both organ-based and patient-based analyses. FDG-PET/CT findings were validated by either biopsy or serial CT/MRI...
May 14, 2016: Oncotarget
Yuji Hotta, Naoya Ieda, Ayako Fukamoto, Tomoya Kataoka, Yoshihiro Kawade, Yasuhiro Maeda, Hidehiko Nakagawa, Kazunori Kimura
PURPOSE: To investigate whether relaxation of the rat penile corpus cavernosum could be controlled with NOBL-1, a novel, light-controllable nitric oxide (NO) releaser. MATERIALS AND METHODS: Fifteen-week-old male Wistar-ST rats were used. The penile corpus cavernosum was prepared and used in an isometric tension study. After noradrenaline (10(-5) M) achieved precontraction, the penile corpus cavernosum was irradiated by light (470-500 nm) with and without NOBL-1 (10(-6) M)...
May 2016: Investigative and Clinical Urology
Yunhan Ma, Jiayu Li, Ge Wang, Qiong Ke, Sien Qiu, Liang Gao, Haifeng Wan, Yang Zhou, Andy Peng Xiang, Qunshan Huang, Guoping Feng, Qi Zhou, Shihua Yang
The efficiency of assisted reproductive technologies (ARTs) in nonhuman primates is low due to no screening criterions for selecting sperm, oocyte, and embryo as well as its surrogate mothers. Here we analyzed 15 pairs of pregnant and non-pregnant cynomolgus monkeys, each pair of which received embryos from one batch of fertilized oocytes, and found ratio of endometrial to myometrial thicknesses in abdominal ultrasonic transverse section of uterus is a reliable indicator for selection of recipients for embryo transfer...
2016: Scientific Reports
Serap Gur, Taylor Peak, Faysal A Yafi, Philip J Kadowitz, Suresh C Sikka, Wayne J G Hellstrom
OBJECTIVE: To examine the effects of mirabegron, a selective β3 -adrenoceptor agonist that has recently been approved for the treatment of overactive bladder (OAB), on erectile function. Stimulation of β3 -adrenoceptors localised in cavernosal smooth muscle cells may play a physiological role in mediating penile erection, and offer a beneficial pharmacological action for patients who have OAB and erectile dysfunction (ED). MATERIALS AND METHODS: Corpus cavernosal (CC) specimens were obtained from patients with ED and Peyronie's disease undergoing penile prosthesis implantation...
September 2016: BJU International
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