keyword
https://read.qxmd.com/read/38656161/impact-of-confinement-and-zwitterionic-ligand-chemistry-on-ion-ion-selectivity-of-functionalized-nanopores
#21
JOURNAL ARTICLE
Harnoor Singh Sachar, Everett S Zofchak, Nico Marioni, Zidan Zhang, Venkat Ganesan
Membranes incorporating zwitterionic chemistries have recently emerged as promising candidates for facilitating challenging ion-ion separations. Transport of ions in such membranes predominantly occurs in hydrated nanopores lined with zwitterionic monomers. To shed light on the physics of ion-ion selectivity underlying such materials, we conducted molecular dynamics simulations of sodium halide transport in model nanopores grafted with sulfobetaine methacrylate molecules. Our results reveal that in both functionalized and unfunctionalized nanopores smaller ions prefer to reside near the pore center, while the larger ions tend to reside near the pore walls...
April 24, 2024: Langmuir: the ACS Journal of Surfaces and Colloids
https://read.qxmd.com/read/38655970/the-overcoming-of-the-monogamous-family-is-through-the-community-non-monogamous-parenting-of-sex-gender-diverse-people
#22
JOURNAL ARTICLE
Alef Diogo da Silva Santana, Adriane Soares Galdino, Ednaldo Cavalcante de Araújo
Sex-gender-diverse and non-monogamous strain cisnormativity and mononormativity. In scientific terms, the parenting arrangements of these people are uncertain. Thus, this ethnography aims to understand the perception of non-monogamous sex-gender-diverse people about parenting. The theoretical framework adopted is derived from non-monogamous studies, love and sexuality from the Social and Human Sciences in Public Health and the digital ethnography methodological framework. Fieldwork occurred from 2021 to 2022 through an online WhatsApp group...
April 2024: Ciência & Saúde Coletiva
https://read.qxmd.com/read/38655963/who-are-the-sexual-and-gender-minorities-who-frequently-interact-with-children-and-their-association-with-healthcare
#23
JOURNAL ARTICLE
Claudia Rafaella Santos Oliveira, Carolina Campos Vieira de Sousa, Juliana Lustosa Torres
This study aimed to examine the sociodemographic profile of sexual and gender minorities who regularly interact with children and investigate whether such frequent interactions are associated with healthcare factors. This cross-sectional study utilized data from the LGBT+ Health Survey in Brazil, conducted online and anonymously from August to November 2020 with 958 participants. Regular interaction with children was defined as living with children or engaging in bi-weekly face-to-face meetings with children residing in different households...
April 2024: Ciência & Saúde Coletiva
https://read.qxmd.com/read/38655902/latching-medical-students-onto-a-virtual-breastfeeding-elective-during-the-covid-19-pandemic
#24
JOURNAL ARTICLE
Suet Kam Lam, Jessica MacWilliams, Lauren C Larkin-Baker, Heidi Szugye, Lydia Furman
Objectives: To describe the implementation of a successful two-week virtual breastfeeding elective for medical students during the COVID-19 pandemic and characterize student demographics, objective knowledge, and perspectives on breastfeeding before and after the elective. Study Design: We adapted the Santa Rosa Kaiser Permanente Family Medicine breastfeeding residency curriculum to create a two-week virtual medical student elective using Kern's six steps of curriculum development and a competency-based education framework...
April 24, 2024: Breastfeeding Medicine
https://read.qxmd.com/read/38655803/assisted-living-residents-with-dementia-disparities-in-mental-health-services-pre-and-during-covid-19
#25
JOURNAL ARTICLE
Helena Temkin-Greener, Yechu Hua, Shubing Cai
BACKGROUND: Little is known about mental health among Medicare beneficiaries with Alzheimer's disease or related dementias (ADRD) who reside in assisted living (AL) communities. The COVID-19 pandemic may have curtailed ambulatory care access for these residents, but telehealth may have expanded it. We examined in-person and telehealth use of ambulatory mental health visits among AL residents with ADRD, pre and during the COVID pandemic, focusing on race/ethnicity and Medicare/Medicaid dual status...
April 24, 2024: Journal of the American Geriatrics Society
https://read.qxmd.com/read/38655777/comparing-accuracy-of-night-radiology-interpretations-for-pediatric-trauma-radiology-residents-versus-attending-teleradiologists
#26
JOURNAL ARTICLE
Alice M Martino, Eric O Yeates, Areg Grigorian, Justine Chinn, Hayley Young, Jessica Colin Escobar, Justin Glavis-Bloom, Arash Anavim, Vahid Yaghmai, Ninh T Nguyen, Matthew Dolich, Sebastian D Schubl, Laura F Goodman, Yigit S Guner, Jeffry Nahmias
Background: Overnight radiology coverage for pediatric trauma patients (PTPs) is addressed with a combination of on-call radiology residents (RRs) and/or attending teleradiologists (ATs); however, the accuracy of these two groups has not been investigated for PTPs. We aimed to compare the accuracy of RRs vs AT interpretations of computed tomography (CT) scans for PTPs. Methods: Pediatric trauma patients (<18 years old) at a single level-I adult/level-II pediatric trauma center were studied in a retrospective analysis (3/2019-5/2020)...
April 24, 2024: American Surgeon
https://read.qxmd.com/read/38655614/graduate-medical-education-success-coaching-for-residents-and-fellows-a-single-institution-real-world-experience
#27
JOURNAL ARTICLE
Charles Redman, Catherine G Chung, Daniel McFarlane, Alexa Meara, Aslam Ejaz
While coaching has been employed as a success strategy in many areas such as athletics and business for decades, its use is relatively new in the medical field despite evidence of its benefits. Implementation and engagement regarding coaching in graduate medical education (GME) for residents and fellows is particularly scarce. We report our three-year experience of a GME success coaching program that aims to help trainees reach their full potential by addressing various areas of medical knowledge, clinical skills, efficiency, interpersonal skills and communication, professionalism, and mental health and well-being...
December 31, 2024: Medical Education Online
https://read.qxmd.com/read/38655566/magnitude-of-thrombocytopenia-and-associated-factors-among-pregnant-women-attending-the-antenatal-care-service-unit-of-wachemo-university-nigist-ellen-mohammed-comprehensive-specialized-hospital-hosanna-southern-ethiopia
#28
JOURNAL ARTICLE
Dembelo Tirago, Tilahun Yemane, Edosa Tadasa
BACKGROUND: Thrombocytopenia is the second most common hematological disorder in pregnancy after anemia worldwide and affects 7-8% of all pregnancies. Pregnant women with thrombocytopenia have complications of excessive bleeding during or after childbirth, exudation at the cesarean section, and neonatal thrombocytopenia. Therefore, the main aim of this study was to assess the magnitude of thrombocytopenia and its associated factors among pregnant women attending the Antenatal Care Service Unit of Wachemo University Nigist Ellen Mohammed Comprehensive Specialized Hospital Hosanna, Southern Ethiopia...
2024: Advances in Hematology
https://read.qxmd.com/read/38655520/an-assessment-of-the-perceptual-elements-of-urban-streets-based-on-the-context-of-urban-tourism-the-case-of-sheffield
#29
JOURNAL ARTICLE
Siqi Huang
BACKGROUND: After COVID-19, more and more travelers are more inclined to walk in cities, and the sensory elements of streets can have a significant impact on urban tourism. Local residents and travelers have different perceptions of the street and preferences for its use. The purpose of this study is to evaluate and analyse the streets from the perspective of locals and travelers. METHOD: In this study, a questionnaire was designed to obtain local residents' and travelers' evaluations of the sensory elements of the street and a quadrant analysis of the street's sensory elements was carried out using the IPA-Kano model...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38655503/persistent-microbial-communities-in-hyperarid-subsurface-habitats-of-the-atacama-desert-insights-from-intracellular-dna-analysis
#30
JOURNAL ARTICLE
Lucas Horstmann, Daniel Lipus, Alexander Bartholomäus, Felix Arens, Alessandro Airo, Lars Ganzert, Pedro Zamorano, Dirk Schulze-Makuch, Dirk Wagner
Desert environments constitute one of the largest and yet most fragile ecosystems on Earth. Under the absence of regular precipitation, microorganisms are the main ecological component mediating nutrient fluxes by using soil components, like minerals and salts, and atmospheric gases as a source for energy and water. While most of the previous studies on microbial ecology of desert environments have focused on surface environments, little is known about microbial life in deeper sediment layers. Our study is extending the limited knowledge about microbial communities within the deeper subsurface of the hyperarid core of the Atacama Desert...
April 2024: PNAS Nexus
https://read.qxmd.com/read/38655500/human-pluripotent-stem-cell-hpsc-derived-microglia-for-the-study-of-brain-disorders-a-comprehensive-review-of-existing-protocols
#31
REVIEW
Fionicca Teo, Catherine Yen Li Kok, Mao-Jia Tan, H Shawn Je
Microglia, resident immune cells of the brain that originate from the yolk sac, play a critical role in maintaining brain homeostasis by monitoring and phagocytosing pathogens and cellular debris in the central nervous system (CNS). While they share characteristics with myeloid cells, they are distinct from macrophages. In response to injury, microglia release pro-inflammatory factors and contribute to brain homeostasis through activities such as synapse pruning and neurogenesis. To better understand their role in neurological disorders, the generation of in vitro models of human microglia has become essential...
June 2024: IBRO neuroscience reports
https://read.qxmd.com/read/38655451/feasibility-of-regional-center-telehealth-visits-utilizing-a-rural-research-network-in-people-with-parkinson-s-disease
#32
JOURNAL ARTICLE
Tuhin Virmani, Lakshmi Pillai, Veronica Smith, Aliyah Glover, Derek Abrams, Phillip Farmer, Shorabuddin Syed, Horace J Spencer, Aaron Kemp, Kendall Barron, Tammaria Murray, Brenda Morris, Bendi Bowers, Angela Ward, Terri Imus, Linda J Larson-Prior, Mitesh Lotia, Fred Prior
BACKGROUND: Impaired motor and cognitive function can make travel cumbersome for People with Parkinson's disease (PwPD). Over 50% of PwPD cared for at the University of Arkansas for Medical Sciences (UAMS) Movement Disorders Clinic reside over 30 miles from Little Rock. Improving access to clinical care for PwPD is needed. OBJECTIVE: To explore the feasibility of remote clinic-to-clinic telehealth research visits for evaluation of multi-modal function in PwPD. METHODS: PwPD residing within 30 miles of a UAMS Regional health center were enrolled and clinic-to-clinic telehealth visits were performed...
2024: Journal of Clinical and Translational Science
https://read.qxmd.com/read/38655422/exploring-the-burden-of-postpartum-depression-in-urban-bangladesh-prevalence-and-its-associations-with-pregnancy-related-factors-from-a-cross-sectional-study
#33
JOURNAL ARTICLE
Firoj Al-Mamun, Most Sabiha Sultana, Marufa Akter Momo, Jyotie Malakar, Saad Bin Bahar, Imtiaz Uddin, Murshida Murshida, Mst Morsheda Akter, Mst Mohsina Begum, Tasmin Sayeed Nodi, Abdullah Al Habib, Mark M Kaggwa, Nitai Roy, Mohammed A Mamun
BACKGROUND AND AIMS: Postpartum depression (PPD) is a globally recognized public health concern, yet research focusing on women in urban areas of Bangladesh remains unexplored. This study aimed to address this research gap by investigating the prevalence and associated factors of PPD within the first 2 years after childbirth. METHODS: A cross-sectional study was conducted, enrolling 259 women (26.66 ± 4.57 years) residing in urban areas who were attending healthcare delivery centers...
April 2024: Health Science Reports
https://read.qxmd.com/read/38655384/atherosclerotic-cardiovascular-disease-risk-among-ghanaians-a-comparison-of-the-risk-assessment-tools
#34
JOURNAL ARTICLE
Francis Agyekum, Florence Koryo Akumiah, Samuel Blay Nguah, Lambert Tetteh Appiah, Khushali Ganatra, Yaw Adu-Boakye, Aba Ankomaba Folson, Harold Ayetey, Isaac Kofi Owusu
OBJECTIVES: Risk stratification is a cornerstone for preventing atherosclerotic cardiovascular disease (ASCVD). Ghana has yet to develop a locally derived and validated ASCVD risk model. A critical first step towards this goal is assessing how the commonly available risk models perform in the Ghanaian population. This study compares the agreement and correlation between four ASCVD risk assessment models commonly used in Ghana. METHODS: The Ghana Heart Study collected data from four regions in Ghana (Ashanti, Greater Accra, Northern, and Central regions) and excluded people with a self-declared history of ASCVD...
June 2024: American journal of preventive cardiology
https://read.qxmd.com/read/38655276/reliability-of-renal-point-of-care-ultrasound-pocus-performed-by-pediatric-postgraduates-to-diagnose-hydronephrosis-in-infants
#35
JOURNAL ARTICLE
Eun Jung Cheon, Jung Min Yoon
PURPOSE: Point-of-care ultrasound (POCUS) has gained prominence in a variety of medical specialties due to advances in ultrasound technology. POCUS has not been fully integrated into pediatric residency training programs despite its widespread use and proven benefits. At our institution, renal POCUS is performed by pediatric residents for the evaluation of hydronephrosis, which is the main pathology for which ultrasound is used in the clinical practice of pediatric nephrology. This study was conducted to evaluate the quality of renal POCUS performed by pediatric residents in infants...
2024: Frontiers in Pediatrics
https://read.qxmd.com/read/38655264/identification-of-a-distinct-cluster-of-gdf15-high-macrophages-induced-by-in-vitro-differentiation-exhibiting-anti-inflammatory-activities
#36
JOURNAL ARTICLE
Chaochao Dai, Hongyu Zhang, Zhijian Zheng, Chun Guang Li, Mingyuan Ma, Haiqing Gao, Qunye Zhang, Fan Jiang, Xiaopei Cui
INTRODUCTION: Macrophage-mediated inflammatory response may have crucial roles in the pathogenesis of a variety of human diseases. Growth differentiation factor 15 (GDF15) is a cytokine of the transforming growth factor-β superfamily, with potential anti-inflammatory activities. Previous studies observed in human lungs some macrophages which expressed a high level of GDF15. METHODS: In the present study, we employed multiple techniques, including immunofluorescence, flow cytometry, and single-cell RNA sequencing, in order to further clarify the identity of such GDF15high macrophages...
2024: Frontiers in Immunology
https://read.qxmd.com/read/38655254/impact-of-inflammatory-preconditioning-on-murine-microglial-proteome-response-induced-by-focal-ischemic-brain-injury
#37
JOURNAL ARTICLE
Dario Lucas Helbing, Fabienne Haas, Emilio Cirri, Norman Rahnis, Therese Thuy Dung Dau, Erika Kelmer Sacramento, Nova Oraha, Leopold Böhm, Trim Lajqi, Pascal Fehringer, Helen Morrison, Reinhard Bauer
Preconditioning with lipopolysaccharide (LPS) induces neuroprotection against subsequent cerebral ischemic injury, mainly involving innate immune pathways. Microglia are resident immune cells of the central nervous system (CNS) that respond early to danger signals through memory-like differential reprogramming. However, the cell-specific molecular mechanisms underlying preconditioning are not fully understood. To elucidate the distinct molecular mechanisms of preconditioning on microglia, we compared these cell-specific proteomic profiles in response to LPS preconditioning and without preconditioning and subsequent transient focal brain ischemia and reperfusion, - using an established mouse model of transient focal brain ischemia and reperfusion...
2024: Frontiers in Immunology
https://read.qxmd.com/read/38655245/disease-burden-attributable-to-respiratory-syncytial-virus-outbreaks-in-long-term-care
#38
JOURNAL ARTICLE
Christina Ferrante, Christina Bancej, Nicole Atchessi
BACKGROUND: Respiratory syncytial virus (RSV) disease burden is significant among children; however, RSV can also cause excess morbidity and mortality among older adults. Populations in long-term care homes (LTCHs) may be at greater risk of exposure and increased infection severity. The objectives of this article are to identify evidence regarding disease burden and outcome severity attributable to RSV outbreaks among residents and staff in LTCHs; and to highlight reported population and outbreak characteristics...
January 1, 2024: Canada Communicable Disease Report
https://read.qxmd.com/read/38655232/adolescents-views-on-oral-health-care-and-promotion-in-norway-everyday-practices-recommendations-and-future-visions
#39
JOURNAL ARTICLE
Marikken Høiseth, Arefe Jasbi
INTRODUCTION: In this study, we aimed to understand adolescents' perspectives on oral health care and promotion. Our research was conducted in the context of Norway's oral health care system, where societal factors like income and education influence health disparities. Despite free public dental care for all residents younger than 19 years, challenges persist in promoting oral health among adolescents, a group whose oral health behavior and literacy remain largely unexplored. MATERIALS AND METHODS: A thematic analysis of an anonymized dataset from 80 adolescents aged 12-20 years was conducted...
2024: Front Oral Health
https://read.qxmd.com/read/38655230/association-between-multimorbidity-and-utilization-of-medical-and-long-term-care-among-older-adults-in-a-rural-mountainous-area-in-japan
#40
JOURNAL ARTICLE
Yuki Kuwabara, Toshihiro Hamada, Tsubasa Nakai, Maya Fujii, Aya Kinjo, Yoneatsu Osaki
OBJECTIVE: With the accelerated population aging, multimorbidity has become an important healthcare issue. However, few studies have examined multimorbidity and its impact on the use of medical and long-term care services in Japan. Therefore, this study aimed to examine the association between multimorbidity and the use of medical and long-term care services among older adults living in the depopulated mountainous areas of Japan. PATIENTS AND METHODS: A cross-sectional study was conducted using insurance claims data from late-stage medical insurance and long-term care insurance (April 2017 to March 2018) for older adults ≥75 years residing in a mountainous area in the Tottori prefecture...
April 2024: Journal of Rural Medicine: JRM
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