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https://www.readbyqxmd.com/read/28231672/-analysis-on-cancer-deaths-and-cause-eliminated-life-expectancy-among-residents-of-tianjin-2015
#1
Z L Xu, H Zhang, D Z Wang, G D Song, C F Shen, S Zhang, Y Zhang, G H Jiang
Objective: To explore the causes of cancer deaths and cause-eliminated-life-expectancy among residents of Tianjin. Methods: Data from the death registry system of Tianjin residents in 2015 were collected and cancers were grouped according to the classification of Global Burden of Disease. Specific cancer crude death rate and cause eliminated life expectancy (CELE) were calculated. Results: In 2015, 17 641 Tianjin residents died of cancer, with the crude death rate as 171.79 per 100 thousand and the standardized rate according to the Chinese population in 2000 as 86...
February 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28231663/-factors-associated-with-lost-of-follow-up-of-men-who-have-sex-with-men-in-a-gay-bathhouse-cohort-study-in-tianjin-2012-2015
#2
Y Guo, N Zhou, J Yang, P Xu, H Gong, M H Yu
Objective: To understand the rate of follow-up lost in men who have sex with men (MSM) in a gay bathhouse cohort study in Tianjin and the associated factors. Methods: The open cohort study in gay bathhouse was launched in 2012 in Tianjin, and the MSM for baseline survey were recruited from January to June 2012, while the follow up was carried out every six months. A questionnaire survey and HIV test were conducted in the study. The MSM who were HIV negative in the baseline survey in 2012 were used for follow up lost analysis...
February 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28231549/assessing-allergenicity-in-urban-parks-a-nature-based-solution-to-reduce-the-impact-on-public-health
#3
Paloma Cariñanos, Manuel Casares-Porcel, Consuelo Díaz de la Guardia, María Jesús Aira, Jordina Belmonte, Marzia Boi, Belén Elvira-Rendueles, Concepción De Linares, Santiago Fernández-Rodriguez, José María Maya-Manzano, Rosa Pérez-Badía, David Rodriguez-de la Cruz, Francisco Javier Rodríguez-Rajo, Jesús Rojo-Úbeda, Carlos Romero-Zarco, Estefanía Sánchez-Reyes, José Sánchez-Sánchez, Rafael Tormo-Molina, Ana Mª Vega Maray
Urban parks play a key role in the provision of ecosystem services, actively participating in improving the quality of life and welfare of local residents. This paper reports on the application of an index designed to quantify the allergenicity of urban parks in a number of Spanish cities. The index, which records biological and biometric parameters for the tree species growing there, classifies parks in terms of the risk they pose for allergy sufferers, graded as null, low, moderate or high. In this initial phase, the index was applied to 26 green areas in 24 Spanish cities; green areas varied in type (urban park, historical or modern garden, boulevard, square or urban forest), size 1-100 ha), geographical location, species richness, number of trees and tree density (number of trees / ha...
February 20, 2017: Environmental Research
https://www.readbyqxmd.com/read/28231508/regulating-dynamic-signaling-between-hematopoietic-stem-cells-and-niche-cells-via-a-hydrogel-matrix
#4
Bhushan P Mahadik, Narayanan A K Bharadwaj, Randy H Ewoldt, Brendan A C Harley
Hematopoietic stem cells (HSC) reside in unique bone marrow niches and are influenced by signals from surrounding cells, the extracellular matrix (ECM), ECM-bound or diffusible biomolecules. Here we describe the use of a three-dimensional hydrogel to alter the balance of HSC-generated autocrine feedback and paracrine signals generated by co-cultured niche-associated cells. We report shifts in HSC proliferation rate and fate specification in the presence of lineage positive (Lin(+)) niche cells. Hydrogels promoting autocrine feedback enhanced expansion of early hematopoietic progenitors while paracrine signals from Lin(+) cells increased myeloid differentiation...
February 14, 2017: Biomaterials
https://www.readbyqxmd.com/read/28231341/identification-of-the-er-resident-e3-ubiquitin-ligase-rnf145-as-a-novel-lxr-regulated-gene
#5
Emma C L Cook, Jessica K Nelson, Vincenzo Sorrentino, Duco Koenis, Martina Moeton, Saskia Scheij, Roelof Ottenhoff, Boris Bleijlevens, Anke Loregger, Noam Zelcer
Cellular cholesterol metabolism is subject to tight regulation to maintain adequate levels of this central lipid molecule. Herein, the sterol-responsive Liver X Receptors (LXRs) play an important role owing to their ability to reduce cellular cholesterol load. In this context, identifying the full set of LXR-regulated genes will contribute to our understanding of their role in cholesterol metabolism. Using global transcriptional analysis we report here the identification of RNF145 as an LXR-regulated target gene...
2017: PloS One
https://www.readbyqxmd.com/read/28231307/differential-regulation-of-c5a-receptor-1-in-innate-immune-cells-during-the-allergic-asthma-effector-phase
#6
Fanny Ender, Anna V Wiese, Inken Schmudde, Jing Sun, Tillman Vollbrandt, Peter König, Yves Laumonnier, Jörg Köhl
C5a drives airway constriction and inflammation during the effector phase of allergic asthma, mainly through the activation of C5a receptor 1 (C5aR1). Yet, C5aR1 expression on myeloid and lymphoid cells during the allergic effector phase is ill-defined. Recently, we generated and characterized a floxed green fluorescent protein (GFP)-C5aR1 knock-in mouse. Here, we used this reporter strain to monitor C5aR1 expression in airway, pulmonary and lymph node cells during the effector phase of OVA-driven allergic asthma...
2017: PloS One
https://www.readbyqxmd.com/read/28231239/surveillance-for-health-care-access-and-health-services-use-adults-aged-18-64-years-behavioral-risk-factor-surveillance-system-united-states-2014
#7
Catherine A Okoro, Guixiang Zhao, Jared B Fox, Paul I Eke, Kurt J Greenlund, Machell Town
PROBLEM/CONDITION: As a result of the 2010 Patient Protection and Affordable Care Act, millions of U.S. adults attained health insurance coverage. However, millions of adults remain uninsured or underinsured. Compared with adults without barriers to health care, adults who lack health insurance coverage, have coverage gaps, or skip or delay care because of limited personal finances might face increased risk for poor physical and mental health and premature mortality. PERIOD COVERED: 2014...
February 24, 2017: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/28231010/generation-of-anisotropic-massless-dirac-fermions-and-asymmetric-klein-tunneling-in-few-layer-black-phosphorus-superlattices
#8
Zhenglu Li, Ting Cao, Meng Wu, Steven G Louie
Artificial lattices have been employed in a broad range of two-dimensional systems, including those with electrons, atoms and photons, in the quest for massless Dirac fermions with high flexibility and controllability. Establishing triangular or hexagonal symmetry, from periodically patterned molecule assembly or electrostatic gating as well as from moiré pattern induced by substrate, has produced electronic states with linear dispersions from two-dimensional electron gas (2DEG) residing in semiconductors, metals and graphene...
February 23, 2017: Nano Letters
https://www.readbyqxmd.com/read/28230967/live-cell-pyrophosphate-imaging-by-in-situ-hot-spot-generation
#9
Mingmin Li, Jin Li, Huixia Di, Huiqiao Liu, Dingbin Liu
Controlling the electromagnetic hot-spot generation is essential for surface-enhanced Raman scattering (SERS) assays. Current hot spot-based SERS assays have been extensively studied in solutions or on substrates. However, probing biospecies by controlling the hot-spot assembly in living systems has not been demonstrated thus far. Herein, we report a background-free SERS probe for imag-ing pyrophosphate (PPi), a biochemically significant anion, in living cells. Intracellular PPi is able to induce the nanoparticle dimeri-zation, thus creating an intense electromagnetic hot spot and dramatically enhancing the signal of the Raman reporters residing in the hot spot...
February 23, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28230831/incidence-of-multiple-myeloma-among-cleanup-workers-of-the-chornobyl-accident-and-their-survival
#10
D Bazyka, N Gudzenko, I Dyagil, N Trotsiuk, E Gorokh, Z Fedorenko, V Chumak, E Bakhanova, I Ilienko, A Romanenko
: The study presents the updated data on the multiple myeloma (MM) incidence in Ukrainian cleanup workers after the Chornobyl accident and their survival. The epidemiological analysis is based on the extended follow-up period to identify new MM cases for higher statistical power and to collect additional data on the disease course and outcome for the survival analysis. The objective of the study was to analyze the MM incidence and survival in Chornobyl cleanup workers in 1996-2013 in comparison with the national MM statistical data...
December 2016: Experimental Oncology
https://www.readbyqxmd.com/read/28230823/polymorphism-of-dna-repair-gene-xpd-lys751gln-and-chromosome-aberrations-in-lymphocytes-of-thyroid-cancer-patients-exposed-to-ionizing-radiation-due-to-the-chornobyl-accident
#11
V M Shkarupa, O Y Mishcheniuk, S O Henyk-Berezovska, V O Palamarchuk, S V Klymenko
: The aim of this work was to analyze the relationship between polymorphisms of DNA repair gene XPD Lys751Gln and frequency and spectrum of chromosome aberrations in the culture of peripheral blood lymphocytes of thyroid cancer (TC) patients having been exposed to ionizing radiation due to the Chornobyl accident. MATERIALS AND METHODS: XPD Lys751Gln polymorphisms were detected by polymerase chain reaction in 102 TC patients including 38 patients exposed to ionizing radiation due to Chornobyl disaster (Chornobyl recovery workers, evacuees, and the residents of contaminated areas), 64 patients without history of ionizing radiation exposure and 45 healthy residents of Ukraine as control group...
December 2016: Experimental Oncology
https://www.readbyqxmd.com/read/28230818/post-chornobyl-remote-radiation-effects-on-human-sperm-and-seminal-plasma-characteristics
#12
S V Andreychenko, A V Klepko, L V Gorban, O A Motryna, L V Grubska, O V Trofimenko
AIM: The research was aimed on analysis of the remote consequences of Chornobyl accident on the reproductive function of men adult residing in Ukraine. MATERIALS AND METHODS: 232 male volunteers with mean age of 34 years (range 20-47) from 5 different regions of Ukraine (Zhytomyr, Ivano-Frankivsk, Kyiv, Poltava, and Kyiv city) were enrolled in cross-sectional studies of long term radiation effects on seminal plasma and sperm. All manipulations, analysis and classification of ejaculates were done accordingly to WHO recommendations...
December 2016: Experimental Oncology
https://www.readbyqxmd.com/read/28230746/oxidation-of-5-chloromethylfurfural-cmf-to-2-5-diformylfuran-dff
#13
Ana I Vicente, Jaime A S Coelho, Svilen P Simeonov, Hristina I Lazarova, Margarita D Popova, Carlos A M Afonso
2,5-Diformylfuran (DFF) is an important biorenewable building block, namely for the manufacture of new polymers that may replace existing materials derived from limited fossil fuel resources. The current reported methods for the preparation of DFF are mainly derived from the oxidation of 5-hydroxymethylfurfural (HMF) and, to a lesser extent, directly from fructose. 5-Chloromethylfurfural (CMF) has been considered an alternative to HMF as an intermediate building block due to its advantages regarding stability, polarity, and availability from glucose and cellulose...
February 20, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28230698/no-difference-in-patient-mortality-in-medical-icus-staffed-by-nps-vs-residents
#14
Karen Rosenberg, Joan Zolot
No abstract text is available yet for this article.
March 2017: American Journal of Nursing
https://www.readbyqxmd.com/read/28230682/do-nps-need-postgraduate-residencies
#15
Roxanne Nelson
Experts cast doubt on the value of additional training.
March 2017: American Journal of Nursing
https://www.readbyqxmd.com/read/28230275/the-development-and-correlates-of-gender-role-attitudes-in-african-american-youth
#16
Chun Bun Lam, Christine Stanik, Susan M McHale
This research examined the longitudinal trajectories and family correlates of gender role attitudes in African American youth in a sample of 166 sibling pairs residing with their mothers and fathers. Multilevel modelling revealed that (1) girls and boys exhibited significant declines in gender attitude traditionality from ages 9 to 15 that levelled off through age 18, (2) mothers' (but not fathers') gender role attitude traditionality was positively related to youth's attitude traditionality, and (3) within-person variation in mothers' (but not fathers') racial discrimination experiences was negatively related to within-person variation in youth's gender role attitude traditionality...
February 23, 2017: British Journal of Developmental Psychology
https://www.readbyqxmd.com/read/28230272/sizing-up-a-superstorm-exploring-the-role-of-recalled-experience-and-attribution-of-responsibility-in-judgments-of-future-hurricane-risk
#17
Laura N Rickard, Z Janet Yang, Jonathon P Schuldt, Gina M Eosco, Clifford W Scherer, Ricardo A Daziano
Research suggests that hurricane-related risk perception is a critical predictor of behavioral response, such as evacuation. Less is known, however, about the precursors of these subjective risk judgments, especially when time has elapsed from a focal event. Drawing broadly from the risk communication, social psychology, and natural hazards literature, and specifically from concepts adapted from the risk information seeking and processing model and the protective action decision model, we examine how individuals' distant recollections, including attribution of responsibility for the effects of a storm, attitude toward relevant information, and past hurricane experience, relate to risk judgment for a future, similar event...
February 23, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28230209/direct-observation-of-the-dynamics-of-single-metal-ions-at-the-interface-with-solids-in-aqueous-solutions
#18
Maria Ricci, William Trewby, Clodomiro Cafolla, Kislon Voïtchovsky
The dynamics of ions adsorbed at the surface of immersed charged solids plays a central role in countless natural and industrial processes such as crystal growth, heterogeneous catalysis, electrochemistry, or biological function. Electrokinetic measurements typically distinguish between a so-called Stern layer of ions and water molecules directly adsorbed on to the solid's surface, and a diffuse layer of ions further away from the surface. Dynamics within the Stern layer remain poorly understood, largely owing to a lack of in-situ atomic-level insights...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28230065/in-vivo-evaluation-of-a-novel-format-of-a-bivalent-her3-targeting-and-albumin-binding-therapeutic-affibody-construct
#19
Tarek Z Bass, Maria Rosestedt, Bogdan Mitran, Fredrik Y Frejd, John Löfblom, Vladimir Tolmachev, Stefan Ståhl, Anna Orlova
Overexpression of human epidermal growth factor receptor 3 (HER3) is involved in resistance to several therapies for malignant tumours. Currently, several anti-HER3 monoclonal antibodies are under clinical development. We introduce an alternative approach to HER3-targeted therapy based on engineered scaffold proteins, i.e. affibody molecules. We designed a small construct (22.5 kDa, denoted 3A3), consisting of two high-affinity anti-HER3 affibody molecules flanking an albumin-binding domain ABD, which was introduced for prolonged residence in circulation...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28229970/molecular-analysis-of-the-human-faecal-archaea-in-a-southern-indian-population
#20
Sandya B Rani, Ramadass Balamurugan, Balakrishnan S Ramakrishna
Archaea are an important constituent of the human gut microbiota, but there is no information on human gut archaea in an Indian population. In this study, faecal samples were obtained from different age groups (neonatal babies, preschool children, school-going children, adolescents, adults and elderly) of a southern Indian population, and from a tribal population also resident in southern India). 16S rRNA gene sequences specific to Archaea were amplified from pooled faecal DNA in each group, sequenced, and aligned against the NCBI database...
March 2017: Journal of Biosciences
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