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https://www.readbyqxmd.com/read/28929437/toxicities-of-monoterpenes-against-housefly-musca-domestica-l-diptera-muscidae
#1
Zhilin Zhang, Yongjian Xie, Yong Wang, Zhufeng Lin, Lihua Wang, Guoyuan Li
The development of natural plant extracts and essential oils will assist to decrease the negative effects of synthetic chemicals. Many plant extracts and essential oils contain monoterpenes, sesquiterpenes, and aliphatic compounds. In the present study, the fumigation activity of 42 pure monoterpenes against housefly, Musca domestica, was evaluated. Results from fumigation tests revealed that ρ-cymene, terpinolene, (±)-menthol, thymol, carvacrol, (-)-carvone, (+)-camphor, (+)-pulegone, (-)-menthone, citral, (±)-citronellal, cuminaldehyde, and citronellyl acetate exhibited strong fumigation activity against M...
September 19, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28915875/plectranthus-amboinicus-essential-oil-and-carvacrol-bioactive-against-planktonic-and-biofilm-of-oxacillin-and-vancomycin-resistant-staphylococcus-aureus
#2
Sara Edwirgens Costa Benício Vasconcelos, Hider Machado Melo, Theodora Thays Arruda Cavalcante, Francisco Eduardo Aragão Catunda Júnior, Mário Geraldo de Carvalho, Francisca Gleire Rodrigues Menezes, Oscarina Viana de Sousa, Renata Albuquerque Costa
BACKGROUND: The emergence of multidrug-resistant bacteria is a worldwide concern and in order to find an alternative to this problem, the occurrence of antimicrobial compounds in Plectranthus amboinicus essential oil was investigated. Thus, this study aims to determine susceptibility of Staphylococcus aureus isolated from food to antibiotics, P. amboinicus essential oil (PAEO) and carvacrol. METHODS: Leaves and stem of P. amboinicus were used for extraction of essential oil (PAEO) by hydrodistillation technique and EO chemical analysis was performed by gas chromatography coupled to a mass spectrometer...
September 16, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28902458/the-impact-of-some-natural-phenolic-compounds-on-carbonic-anhydrase-acetylcholinesterase-butyrylcholinesterase-and-%C3%AE-glycosidase-enzymes-an-antidiabetic-anticholinergic-and-antiepileptic-study
#3
Parham Taslimi, Cuneyt Caglayan, İlhami Gulcin
Natural products from food and plant sources have been used for medicinal usage for ages. Also, natural products with therapeutic significance are compounds derived from animals, plants, or any microorganism. In this study, chrysin, carvacrol, hesperidin, zingerone, and naringin as natural phenols showed excellent inhibitory effects against human (h) carbonic anhydrase (CA) isoforms I and II (hCA I and II), α-glucosidase (α-Gly), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE). These phenolic compounds were tested for the inhibition of α-glycosidase, hCA I, hCA II, AChE, and BChE enzymes and demonstrated efficient inhibition profiles with Ki values in the range of 3...
September 13, 2017: Journal of Biochemical and Molecular Toxicology
https://www.readbyqxmd.com/read/28893105/essential-oil-composition-of-aerial-parts-of-micromeria-persica-boiss-from-western-of-shiraz-iran
#4
Efat Jafari, Gholamabbas Ghanbarian, Atefeh Bahmanzadegan
Micromeria persica Boiss. is medicinal and aromatic plant, belonging to the Lamiaceae family. The chemical composition of the essential oils (EOs) from aerial parts of M. persica were extracted using hydro-distillation method and analysed using GC and GC-MS. Fifty-two compounds were identified in the EOs of aerial parts of M. persica. The main chemical compositions were n-hexadecanoic acid (14.9%), thymol (9.5%), linoleic acid (8.0%), carvacrol (5.6%), (E)-nerolidol (5.5%), linolenic acid (5.5%), α-cadinol (2...
September 11, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28889001/decontamination-of-fresh-cut-cucumber-slices-by-a-combination-of-a-modified-chitosan-coating-containing-carvacrol-nanoemulsions-and-pulsed-light
#5
Özge Taştan, Gianpiero Pataro, Francesco Donsì, Giovanna Ferrari, Taner Baysal
In this study, the impact of the combination of pulsed light (PL) treatments with antimicrobial coatings, consisting of modified chitosan suspensions incorporating carvacrol nanoemulsions, was investigated on the decontamination of fresh-cut cucumber slices. The upper surface of the cucumber slices, with or without the coating deposition, was inoculated with Escherichia coli ATCC 26 to reach a final concentration of 10(7)CFU/g of the vegetable. PL treatments were conducted at different fluence (4, 8, and 12J/cm(2)) on the inoculated surface of cucumber slices...
August 16, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28888732/are-all-phytochemicals-useful-in-the-preventing-of-dna-damage
#6
REVIEW
Merve Bacanlı, Sevtap Aydın, A Ahmet Başaran, Nurşen Başaran
Phytochemicals derived from natural plants have been used commonly for the prevention and/or treatment of different diseases due to the belief of their safety. Many plant species synthesize toxic chemicals. New natural chemicals are being discovered but their toxic effects are unknown. Phytochemicals have been regarded as possible antioxidants. But on the other hand it is suggested that various phenolic antioxidants can display pro-oxidant properties at high doses. In this review, the role of some phytochemicals (epigallocathecin gallate, carvacrol, galangin, limonene, lycopene, naringin, puerarin, terpinene, thymol and ursolic acid) on the prevention of DNA damage will be discussed...
September 6, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28886313/susceptibility-of-herpes-simplex-virus-type-1-to-monoterpenes-thymol-carvacrol-p-cymene-and-essential-oils-of-sinapis-arvensis-l-lallemantia-royleana-benth-and-pulicaria-vulgaris-gaertn
#7
J Sharifi-Rad, B Salehi, P Schnitzler, S A Ayatollahi, F Kobarfard, M Fathi, M Eisazadeh, M Sharifi-Rad
In recent years, with increased the prevalence of viral infections and having no specific for  their treatment  and also the continuous appearance of resistant viral strains, the finding of novel antiviral agents is necessary. In this study, monoterpenes of thymol, carvacrol, p-cymene and essential oils from Sinapis arvensis L., Lallemantia royleana Benth. and Pulicaria vulgaris Gaertn. were screened for their inhibitory effect against herpes simplex virus type 1 (HSV-1) in vitro on Vero cell line CCL-81-ATCC using a plaque reduction assay...
August 30, 2017: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/28872904/carvacrol-induces-reactive-oxygen-species-ros-mediated-apoptosis-along-with-cell-cycle-arrest-at-g0-g1-in-human-prostate-cancer-cells
#8
Fahad Khan, Imran Khan, Arshi Farooqui, Irfan A Ansari
Carvacrol, a major monoterpenoid phenol from Origanum and Thymus species, has been shown to exhibit antiproliferative and anticancer properties in a few recent studies. Nevertheless, detailed mechanism of the action of this compound in prostate cancer has not been elucidated yet. Therefore, in the current study, we examined the anticancer activity and mechanism of the action of carvacrol against human prostate cancer cells. It was found that the treatment of DU145 cells with carvacrol decreased cell viability in a concentration and time-dependent manner...
September 5, 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28869828/is-the-biocompatibility-of-copper-with-polymerized-natural-coating-dependent-on-the-potential-selected-for-the-electropolymerization-process
#9
M Bertuola, C A Grillo, D E Pissinis, E D Prieto, M Fernández Lorenzo de Mele
With the intention of taking care of the environment and human health, the development of alternative eco-friendly methods to inhibit metal corrosion is intensively encouraged. In previous works we showed that some phytocompounds components of essential oils such as carvacrol (Carv) and thymol (TOH) are able to be electropolymerized on metals and they seem to be promissory for this purpose. The aim this paper is to investigate if the biocompatibility of copper covered by coatings formed by electropolymerization of Carv and TOH (polyCarv and polyTOH) is related with the potential selected for the electropolymerization process...
August 24, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28867805/cytotoxic-activity-of-origanum-vulgare-l-on-hepatocellular-carcinoma-cell-line-hepg2-and-evaluation-of-its-biological-activity
#10
Hazem S Elshafie, Maria F Armentano, Monica Carmosino, Sabino A Bufo, Vincenzo De Feo, Ippolito Camele
The potential of plant essential oils (EOs) in anticancer treatment has recently received many research efforts to overcome the development of multidrug resistance and their negative side effects. The aims of the current research are to study (i) the cytotoxic effect of the crude EO extracted from Origanum vulgare subsp hirtum and its main constituents (carvacrol, thymol, citral and limonene) on hepatocarcinoma HepG2 and healthy human renal cells HEK293; (ii) the antibacterial and phytotoxic activities of the above EO and its main constituents...
August 30, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28843125/combination-of-essential-oil-compounds-and-phenolic-acids-against-escherichia-coli-o157-h7-in-vitro-and-in-dry-fermented-sausage-production
#11
Natan V B Meira, Richard A Holley, Keliani Bordin, Renata E F de Macedo, Fernando B Luciano
Escherichia coli O157:H7 is a foodborne pathogen that causes hemorrhagic colitis and hemolytic uremic syndrome. The low dose of infection and severity of the disease represent a concern to public health. Natural compounds have been widely applied as food additives to replace synthetic preservatives. The aim of this study was to determine the efficiency of essential oil compounds (EOCs) in combination with phenolic acids (PA) in vitro and in dry-fermented sausage production. Minimum Inhibitory Concentration (MIC) and Fractional Inhibitory Concentration index (FICindex) were determined for a 5-strain mixture of E...
August 16, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28837070/mechanisms-of-antimicrobial-action-of-cinnamon-and-oregano-oils-cinnamaldehyde-carvacrol-2-5-dihydroxybenzaldehyde-and-2-hydroxy-5-methoxybenzaldehyde-against-mycobacterium-avium-subsp-paratuberculosis-map
#12
Stella W Nowotarska, Krzysztof Nowotarski, Irene R Grant, Christopher T Elliott, Mendel Friedman, Chen Situ
The antimicrobial modes of action of six naturally occurring compounds, cinnamon oil, cinnamaldehyde, oregano oil, carvacrol, 2,5-dihydroxybenzaldehyde, and 2-hydroxy-5-methoxybenzaldehyde, previously found to inhibit the growth of Mycobacterium avium subsp. paratuberculosis (Map) reported to infect food animals and humans and to be present in milk, cheese, and meat, were investigated. The incubation of Map cultures in the presence of all six compounds caused phosphate ions to leak into the extracellular environment in a time- and concentration-dependent manner...
August 24, 2017: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28830763/carvacrol-promotes-angiogenic-paracrine-potential-and-endothelial-differentiation-of-human-mesenchymal-stem-cells-at-low-concentrations
#13
Danial Matluobi, Atefeh Araghi, Behnaz Faramarzian Azimi Maragheh, Aysa Rezabakhsh, Sina Soltani, Majid Khaksar, Vahid Siavashi, Adel Feyzi, Hesam Saghaei Bagheri, Reza Rahbarghazi, Soheila Montazersaheb
OBJECTIVES: Phenolic monoterpene compound, named Carvacrol, has been found to exert different biological outcomes. It has been accepted that the angiogenic activity of human mesenchymal stem cells was crucial in the pursuit of appropriate regeneration. In the current experiment, we investigated the contribution of Carvacrol on the angiogenic behavior of primary human mesenchymal stem cells. METHODS: Mesenchymal stem cells were exposed to Carvacrol in a dose ranging from 25 to 200μM for 48h...
August 19, 2017: Microvascular Research
https://www.readbyqxmd.com/read/28807309/synergistic-interaction-of-ten-essential-oils-against-haemonchus-contortus-in-vitro
#14
L M Katiki, A M E Barbieri, R C Araujo, C J Veríssimo, H Louvandini, J F S Ferreira
Anthelmintic resistance in sheep gastrointestinal nematodes is a worldwide problem. Multi-drug resistant haemonchosis is the most serious impediment for small ruminant systems, and there are no new drug candidates currently under development. Molecules from natural sources have demonstrated anthelmintic activity against parasites. In this work, the monoterpenoids carvacrol, carvone, cineole, linalool, limonene, and thymol and the phenylpropanoids cinnamaldehyde, anethole, vanillin, and eugenol were assessed individually or in mixtures of ten binary, three ternary, and three quaternary combinations using the in vitro egg hatch assay with eggs of a multi-drug resistant strain of Haemonchus contortus...
August 30, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28805907/evaluation-of-essential-oils-and-prebiotics-for-newborn-dairy-calves
#15
K A Froehlich, K W Abdelsalam, C Chase, J Koppien-Fox, D P Casper
A blend of essential oils (EO; carvacrol, caryophyllene, -cymene, cineole, terpinene, and thymol) and prebiotics (arabinogalactans; Stay Strong; Ralco, Inc., Marshall, MN) was designed to promote immunity and stimulate appetite to diminish health challenges and stresses experienced by newborn calves. It was hypothesized that calves supplemented with the medium dose (2.5 g/feeding) of the commercial EO would demonstrate the optimal response. The study objective was to determine the optimal feeding rate of EO when added to a milk replacer (MR) compared with feeding a control or a yeast cell wall additive (YCW)...
August 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28795522/assessment-of-carvacrol-for-control-of-avian-aspergillosis-in-intratracheally-challenged-chickens-in-comparison-to-voriconazole-with-a-reference-on-economic-impact
#16
Y H Tartor, F A M Hassan
AIM: This study was designed to investigate the efficacy of essential oils (EOs) as an alternative prophylaxis and treatment for avian aspergillosis. METHODS AND RESULTS: The in vitro susceptibility of A. fumigatus strains to antifungal drugs and carvacrol, thymol, eugenol, thymoquinone and cinnamon was determined using the macro-diffusion and microdilution methods. Carvacrol has antifungal activity in comparison to voriconazole (VCZ) (MIC 0.5, 0.25μg/ml, respectively)...
August 9, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28762217/acute-toxicity-and-sublethal-effects-of-terpenoids-and-essential-oils-on-the-predator-chrysoperla-externa-neuroptera-chrysopidae
#17
R V Castilhos, A D Grützmacher, J R Coats
The search for new safer insecticides has increased in recent agriculture. Botanical compounds such as terpenoids and plant essential oils with insecticidal activity could represent important tools in pest management, and their risk assessment against non-target organisms is necessary since they may serve as a precursor for the synthesis of new insecticide active ingredients. For this study, the acute toxicity and sublethal effects of seven terpenoids and three essential oils with recognized insecticidal activity were evaluated on the predator Chrysoperla externa (Hagen) (Neuroptera: Chrysopidae) in laboratory bioassays...
July 31, 2017: Neotropical Entomology
https://www.readbyqxmd.com/read/28759796/inhibition-of-salmonella-by-thyme-essential-oil-and-its-effect-on-microbiological-and-sensory-properties-of-minced-pork-meat-packaged-under-vacuum-and-modified-atmosphere
#18
Marija Boskovic, Jasna Djordjevic, Jelena Ivanovic, Jelena Janjic, Nemanja Zdravkovic, Milica Glisic, Natasa Glamoclija, Branislav Baltic, Vesna Djordjevic, Milan Baltic
The antibacterial activity of thyme essential oil (TEO) was evaluated against four serovars of Salmonella (S. Enteritidis, S. Typhimurium, S. Montevideo and S. Infantis), experimentally inoculated (10(6)CFU/g) in minced pork, which was treated with different concentrations of the TEO (0.3%, 0.6% and 0.9%) packaged under vacuum or MAP (30%O2/50%CO2/20% N2) and stored at 3±1°C for 15days. GC-MS analysis of the TEO was performed in order to determine composition, and the predominant constituent was thymol (50...
July 20, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28745768/the-sos-chromotest-applied-for-screening-plant-antigenotoxic-agents-against-ultraviolet-radiation
#19
J L Fuentes, A García Forero, N Quintero Ruiz, C A Prada Medina, N Rey Castellanos, D A Franco Niño, D A Contreras García, Y Córdoba Campo, E E Stashenko
In this work, we investigated the usefulness of the SOS Chromotest for screening plant antigenotoxic agents against ultraviolet radiation (UV). Fifty Colombian plant extracts obtained by supercritical fluid (CO2) extraction, twelve plant extract constituents (apigenin, carvacrol, β-caryophyllene, 1,8-cineole, citral, p-cymene, geraniol, naringenin, pinocembrin, quercetin, squalene, and thymol) and five standard antioxidant and/or photoprotective agents (curcumin, epigallocatechin gallate, resveratrol, α-tocopherol, and Trolox®) were evaluated for their genotoxicity and antigenotoxicity against UV using the SOS Chromotest...
September 13, 2017: Photochemical & Photobiological Sciences
https://www.readbyqxmd.com/read/28738439/terpenoids-from-the-oleo-gum-resin-of-boswellia-serrata-and-their-antiplasmodial-effects-in-vitro
#20
Hippolyt L Greve, Marcel Kaiser, Reto Brun, Thomas J Schmidt
In the course of our ongoing search for new natural products as leads against protozoal diseases, the dichloromethane extract of Indian frankincense, the oleo-gum-resin obtained from Boswellia serrata, showed in vitro activity against Plasmodium falciparum. Bioactivity-guided fractionation led to the isolation of eight diterpenes: (1S,3E,7E,11R)-verticilla-3,7,12(18)-triene (1), cembrene A (2), serratol (3), 1S,3E,7R,8R,11E-7,8-epoxy-cembra-3,11-dien-1-ol (4), incensole oxide (5), rel (1S,3R,7E,11S,12R)-1,12-epoxy-4-methylenecembr-7-ene-3, 11-diol (6), isoincensole oxide (7), and isodecaryiol (8)...
July 24, 2017: Planta Medica
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