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Phosphate food additive

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https://www.readbyqxmd.com/read/28722443/quantum-dot-nanotoxicity-investigations-using-human-lung-cells-and-toxor-electrochemical-enzyme-assay-methodology
#1
Tony O'Hara, Brian Seddon, Andrew O'Connor, Siobhán McClean, Baljit Singh, Emmanuel Iwuoha, Xolile Fuku, Eithne Dempsey
Recent studies have suggested that certain nanomaterials can interfere with optically based cytotoxicity assays resulting in underestimations of nanomaterial toxicity. As a result there has been growing interest in the use of whole cell electrochemical biosensors for nanotoxicity applications. Herein we report application of an electrochemical cytotoxicity assay developed in house (TOXOR) in the evaluation of toxic effects of mercaptosuccinic acid capped cadmium telluride quantum dots (MSA capped CdTe QDs), toward mammalian cells...
January 27, 2017: ACS Sensors
https://www.readbyqxmd.com/read/28704952/the-inhibitory-effect-of-tartary-buckwheat-extracts-on-adipogenesis-and-inflammatory-response
#2
Mak-Soon Lee, Yoonjin Shin, Sunyoon Jung, Seog-Young Kim, Young-Hee Jo, Chong-Tai Kim, Min-Kyu Yun, Sung-Jin Lee, Johann Sohn, Heui-Jong Yu, Yangha Kim
Tartary buckwheat (Fagopyrum tataricum) has been established globally as a nutritionally important food item, particularly owing to high levels of bioactive compounds such as rutin. This study investigated the effect of tartary buckwheat extracts (TBEs) on adipogenesis and inflammatory response in 3T3-L1 cells. TBEs inhibited lipid accumulation, triglyceride content, and glycerol-3-phosphate dehydrogenase (GPDH) activity during adipocyte differentiation of 3T3 L1 cells. The mRNA levels of genes involved in fatty acid synthesis, such as peroxisome proliferator-activated receptor-γ (PPAR-γ), CCAAT/enhancer binding protein-α (CEBP-α), adipocyte protein 2 (aP2), acetyl-CoA carboxylase (ACC), fatty acid synthase (FAS), and stearoylcoenzyme A desaturase-1 (SCD-1), were suppressed by TBEs...
July 12, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28690304/determination-of-residues-of-phenicol-drugs-in-ayu-plecoglossus-altivelis-by-lc-ms-ms
#3
Tomiaki Minatani, Yuka Sakamoto, Hiroyuki Nagai, Kotaro Goto
An analytical method for the determination of residues of 3 phenicol drugs (chloramphenicol, thiamphenicol and florfenicol) in Ayu (Plecoglossus altivelis) by LC-MS/MS was developed. We used the whole body of Ayu, including the bones and internal organs, in addition to muscle. Phenicols were extracted with 90% acetonitrile and an aliquot of the crude extract was cleaned up on a Florisil column (2 g), followed by defatting with n-hexane. The acetonitrile extract was evaporated and the solvent was replaced with phosphate buffer, then the extract was purified on a hydroxylated styrene-divinylbenzene copolymer column (200 mg)...
2017: Shokuhin Eiseigaku Zasshi. Journal of the Food Hygienic Society of Japan
https://www.readbyqxmd.com/read/28667635/genetically-modified-phytase-crops-role-in-sustainable-plant-and-animal-nutrition-and-ecological-development-a-review
#4
REVIEW
Chinreddy Subramanyam Reddy, Seong-Cheol Kim, Tanushri Kaul
Globally, plant-derivatives especially cereals and legumes are the major staple food sources for animals. The seeds of these crops comprise of phytic acid, the major repository form of the phosphorus, which is not digestible by simple-stomached animals. However, it is the most important factor responsible for impeding the absorption of minerals by plants that eventually results in less use of fertilizers that ultimately cause eutrophication in water bodies. Although abundant phosphorus (P) exists in the soils, plants cannot absorb most of the P due to its conversion to unavailable forms...
July 2017: 3 Biotech
https://www.readbyqxmd.com/read/28661431/colonization-and-maize-growth-promotion-induced-by-phosphate-solubilizing-bacterial-isolates
#5
Yongbin Li, Xiaomeng Liu, Tianyi Hao, Sanfeng Chen
Phosphorus (P) limits the production of maize, one of the major food crops in China. Phosphate-solubilizing bacteria (PSB) have the capacity to solubilize phosphate complexes into plant absorbable and utilizable forms by the process of acidification, chelation, and exchange reactions. In this study, six bacteria, including one Paenibacillus sp. B1 strain, four Pseudomonas sp. strains (B10, B14, SX1, and SX2) and one Sphingobium sp. SX14 strain, were those isolated from the maize rhizosphere and identified based on their 16S rRNA sequences...
June 29, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28660192/global-phosphorus-fertilizer-market-and-national-policies-a-case-study-revisiting-the-2008-price-peak
#6
Nikolay Khabarov, Michael Obersteiner
The commodity market super-cycle and food price crisis have been associated with rampant food insecurity and the Arab spring. A multitude of factors were identified as culprits for excessive volatility on the commodity markets. However, as it regards fertilizers, a clear attribution of market drivers explaining the emergence of extreme price events is still missing. In this paper, we provide a quantitative assessment of the price spike of the global phosphorus fertilizer market in 2008 focusing on diammonium phosphate (DAP)...
2017: Frontiers in Nutrition
https://www.readbyqxmd.com/read/28659517/a-novel-growth-method-for-diatom-algae-in-aquaculture-waste-water-for-natural-food-development-and-nutrient-removal
#7
Xiao-Li Li, Thomas Kiran Marella, Ling Tao, Liang Peng, Chao-Feng Song, Li-Li Dai, Archana Tiwari, Gu Li
Diatom algae are known to play an important role as primary producers in many diverse ecosystems, including artificial aquaculture ponds where they also aid in maintaining water quality by consuming excess nutrients. But factors influencing their growth are still poorly understood. In the present study the effect of micronutrients, N:P ratio and silica concentration on benthic diatom Synedra sp. grown in fish pond waste water was studied along with nutrient removal efficiency. We have studied nine different treatments, of which addition of micronutrient mixture Nualgi along with adjusted N:P to 6:1 resulted in highest cell density, followed by silicate enrichment, whereas only N:P adjustment and Nualgi addition had no significant effect on diatom growth...
June 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28640802/peroxisomal-biogenesis-is-genetically-and-biochemically-linked-to-carbohydrate-metabolism-in-drosophila-and-mouse
#8
Michael F Wangler, Yu-Hsin Chao, Vafa Bayat, Nikolaos Giagtzoglou, Abhijit Babaji Shinde, Nagireddy Putluri, Cristian Coarfa, Taraka Donti, Brett H Graham, Joseph E Faust, James A McNew, Ann Moser, Marco Sardiello, Myriam Baes, Hugo J Bellen
Peroxisome biogenesis disorders (PBD) are a group of multi-system human diseases due to mutations in the PEX genes that are responsible for peroxisome assembly and function. These disorders lead to global defects in peroxisomal function and result in severe brain, liver, bone and kidney disease. In order to study their pathogenesis we undertook a systematic genetic and biochemical study of Drosophila pex16 and pex2 mutants. These mutants are short-lived with defects in locomotion and activity. Moreover these mutants exhibit severe morphologic and functional peroxisomal defects...
June 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28611491/phytases-of-probiotic-bacteria-characteristics-and-beneficial-aspects
#9
REVIEW
P Priyodip, P Y Prakash, S Balaji
Probiotics play a vital role in clinical applications for the treatment of diarrhea, obesity and urinary tract infections. Phytate, an anti-nutrient, chelates essential minerals that are vital for human health. In the past few decades, research reports emphasize extensively on phytate degradation in animals. There is a growing need for finding alternate strategies of phytate utilization in human, as they are unable to produce phytase. At this juncture, probiotics can be utilized for phytase production to combat mineral deficiency in humans...
June 2017: Indian Journal of Microbiology
https://www.readbyqxmd.com/read/28604598/influence-of-food-characteristics-and-food-additives-on-the-antimicrobial-effect-of-garlic-and-oregano-essential-oils
#10
Juan García-Díez, Joana Alheiro, Ana Luisa Pinto, Luciana Soares, Virgilio Falco, Maria João Fraqueza, Luis Patarata
Utilization of essential oils (EOs) as antimicrobial agents against foodborne disease has gained importance, for their use as natural preservatives. Since potential interactions between EOs and food characteristics may affect their antimicrobial properties, the present work studies the influence of fat, protein, pH, aw and food additives on the antimicrobial effect of oregano and garlic EOs against Salmonella spp. and Listeria monocytogenes. Results showed that protein, pH, aw, presence of beef extract, sodium lactate and nitrates did not influence their antimicrobial effect...
June 10, 2017: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28588376/phosphate-additive-avoidance-in-chronic-kidney-disease
#11
David E St-Jules, David S Goldfarb, Mary Lou Pompeii, Mary Ann Sevick
IN BRIEF Dietary guidelines for patients with diabetes extend beyond glycemic management to include recommendations for mitigating chronic disease risk. This review summarizes the literature suggesting that excess dietary phosphorus intake may increase the risk of skeletal and cardiovascular disease in patients who are in the early stages of chronic kidney disease (CKD) despite having normal serum phosphorus concentrations. It explores strategies for limiting dietary phosphorus, emphasizing that food additives, as a major source of highly bioavailable dietary phosphorus, may be a suitable target...
May 2017: Diabetes Spectrum: a Publication of the American Diabetes Association
https://www.readbyqxmd.com/read/28585197/human-protein-kinases-and-obesity
#12
Atilla Engin
The action of protein kinases and protein phosphatases is essential for multiple physiological responses. Each protein kinase displays its own unique substrate specificity, and a regulatory mechanism that may be modulated by association with other proteins. Protein kinases are classified by the target amino acid in their substrates. Some protein kinases can phosphorylate both serine/threonine, as well as tyrosine residues. This group of kinases has been known as dual specificity kinases. Unlike the dual specificity kinases, a heterogeneous group of protein phosphatases are known as dual-specificity phosphatases...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28559627/physico-chemical-functional-and-rheological-properties-of-milk-protein-concentrate-60-as-affected-by-disodium-phosphate-addition-diafiltration-and-homogenization
#13
Ganga Sahay Meena, Ashish Kumar Singh, Sumit Arora, Sanket Borad, Rajan Sharma, Vijay Kumar Gupta
Ultrafiltration and diafiltration of skim milk altered delicate salt equilibrium and composition of 5× UF retentate (5× UFR), and thus adversely affected the reconstitutional and functional properties of milk protein concentrate (MPC) powders. It might be due to interaction and aggregation of proteins during spray drying. Therefore, this study was envisaged to investigate the effect of disodium phosphate (DSP) addition, diafiltration and homogenization of retentates on physico-chemical, functional and rheological properties of MPC60 powders...
May 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28533178/mucin-and-carbohydrate-stimulated-adhesion-and-subproteome-changes-of-the-probiotic-bacterium-lactobacillus-acidophilus-ncfm
#14
Hasan Ufuk Celebioglu, Sita Vaag Olesen, Kennie Prehn, Sampo J Lahtinen, Susanne Brix, Maher Abou Hachem, Birte Svensson
Adhesion to intestinal mucosa is a crucial property for probiotic bacteria. Adhesion is thought to increase host-bacterial interactions, thus potentially enabling health benefits to the host. Molecular events connected with adhesion and surface proteome changes were investigated for the probiotic Lactobacillus acidophilus NCFM cultured with established or emerging prebiotic carbohydrates as carbon source and in the presence of mucin, the glycoprotein of the epithelial mucus layer. Variation in adhesion to HT29-cells and mucin was associated with carbon source and mucin-induced subproteome abundancy differences...
May 19, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/28531397/most-consumed-processed-foods-by-patients-on-hemodialysis-alert-for-phosphate-containing-additives-and-the-phosphate-to-protein-ratio
#15
Marcela T Watanabe, Raphael M Araujo, Barbara P Vogt, Pasqual Barretti, Jacqueline C T Caramori
BACKGROUND AND AIMS: Hyperphosphatemia is common in patients with chronic kidney disease (CKD) stages IV and V because of decreased phosphorus excretion. Phosphatemia is closely related to dietary intake. Thus, a better understanding of sources of dietary phosphate consumption, absorption and restriction, particularly inorganic phosphate found in food additives, is key to prevent consequences of this complication. Our aims were to investigate the most commonly consumed processed foods by patients with CKD on hemodialysis, to analyze phosphate and protein content of these foods using chemical analysis and to compare these processed foods with fresh foods...
August 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28530588/capillary-electrophoresis-coupled-to-mass-spectrometry-employing-hexafluoro-2-propanol-for-the-determination-of-nucleosides-and-nucleotide-mono-di-and-tri-phosphates-in-baby-foods
#16
María Mateos-Vivas, Javier Domínguez-Álvarez, Encarnación Rodríguez-Gonzalo, Rita Carabias-Martínez
The present work describes a method for the simultaneous determination of unmodified nucleosides and nucleotide mono-, di- and tri-phosphates by capillary electrophoresis coupled to mass spectrometry (CE-MS). The use of hexafluoro-2-propanol (HFIP) in the separation medium, and as an additive to the sheath liquid of the electrospray interface (ESI), generated a highly efficient and sensitive method. Instrumental limits of detection in the range of 14-53ngmL(-1) for nucleosides and 7-23, 20-49 and 64-124ngmL(-1) for nucleotide mono-, di-, and tri-phosphates, respectively, were found...
October 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28508978/acute-tumoral-calcinosis-due-to-severe-hyperphosphatemia-in-a-maintenance-hemodialysis-patient
#17
Keizo Nishime, Hiroki Takahashi
We report the case of a maintenance hemodialysis patient with severe hyperphosphatemia (26.6 mg/dL) who developed acute tumoral calcinosis. The patient started receiving maintenance hemodialysis after being diagnosed with type 2 diabetes mellitus. The patient's phosphate levels suddenly increased. He had not taken the prescribed phosphate binders for the past 5 years. He noticed swelling of the palmar aspects of his right thumb, which was diagnosed as tumoral calcinosis. His serum phosphate level reached 26...
November 2016: CEN Case Reports
https://www.readbyqxmd.com/read/28501185/simultaneous-voltammetric-determination-of-vanillin-and-caffeine-in-food-products-using-an-anodically-pretreated-boron-doped-diamond-electrode-its-comparison-with-hplc-dad
#18
Hoshyar Saadi Ali, Abdullah A Abdullah, Pınar Talay Pınar, Yavuz Yardım, Zühre Şentürk
This paper describes an electroanalytical method for the simultaneous determination of vanillin (VAN) and caffeine (CAF) using an anodically pretreated boron-doped diamond electrode. Selective determination of one compound in the presence of other one was also realized. Both compounds yielded a single irreversible oxidation peak using cyclic voltammetry. The nature of the electrode reaction was found to be diffusion controlled with contribution of adsorption. By using square-wave adsorptive stripping voltammetry after 60s accumulation under open-circuit voltage, method allowed simultaneous determination of VAN and CAF in phosphate buffer, pH 2...
August 1, 2017: Talanta
https://www.readbyqxmd.com/read/28448011/turbidimetry-on-human-washed-platelets-the-effect-of-the-pannexin1-inhibitor-brilliant-blue-fcf-on-collagen-induced-aggregation
#19
Filippo Molica, Séverine Nolli, Pierre Fontana, Brenda Renata Kwak
Turbidimetry is a laboratory technique that is applied to measure the aggregation of platelets suspended in either plasma (platelet-rich plasma, PRP) or in buffer (washed platelets), by the use of one or a combination of agonists. The use of washed platelets separated from their plasma environment and in the absence of anticoagulants allows for studying intrinsic platelet properties. Among the large panel of agonists, arachidonic acid (AA), adenosine di-phosphate (ADP), thrombin and collagen are the most frequently used...
April 6, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28429548/is-serum-phosphate-a-useful-target-in-patients-with-chronic-kidney-disease-and-what-is-the-role-for-dietary-phosphate-restriction
#20
Nigel D Toussaint, Stephen G Holt
A complex system of endocrine and paracrine signals exists to control phosphate balance. Dysregulation of these systems in patients with chronic kidney disease has serious clinical consequences. Whilst observational studies have shown associations between higher serum phosphate levels and poor clinical outcomes, the direction of causality has not been demonstrated. Whether there is a target level of serum phosphate remains controversial and no randomized trials to date have proved that strategies to lower extracellular phosphate actually improve clinical outcomes...
March 2017: Nephrology
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